Pub Date : 2021-06-01DOI: 10.1177/08987564211048659
Anderson
s From Other Journals Characterization of the Oral Microbiome in Canine Chronic Ulcerative Stomatitis Anderson JG, Paster BJ, Kokaras A, Chen T. J Immun Res. 2021;7(1):1037 Canine chronic ulcerative stomatitis is a debilitating, oral mucosal disorder of dogs. A commonly held hypothesis for pathogenesis is that bacterial plaque on tooth surfaces is responsible for the ulcerative mucosal lesions. As such, therapy has focused on fullmouth, tooth extraction. Recent studies revealed a unique leukocyte profile in canine ulcerative stomatitis that is amenable to immune modulating therapy. What remains unknown is the role bacteria may play in dysbiosis and immune-inflammatory mechanisms. The microbiota of canine ulcerative stomatitis has not been characterized. Aims of the present study include determination of themicrobiomeofmucosal lesions in canine ulcerative stomatitis and that of the supragingival plaque of the opposing tooth. Themicrobiota of these surfaceswas compared to healthymucosa in the canine ulcerative stomatitis patient, and three non-stomatitis control patients. Our hypothesis was that specific microbial species or complexes are associated with ulcerative stomatitis. DNA from 100 clinical samples was evaluated using Next Generation Sequencing methods and was analyzed using LDA Effect Size and the non-parametric factorial Kruskal-Wallis sum-rank test. Statistically significant differences in species were determined frommucosal ulcers versus normal sites in ulcerative stomatitis patients. Species that were more prevalent on the ulcer lesions included putative periodontal pathogens, such as a Tannerella forsythia-like phylotype and Porphyromonas gingivicanis, a species related to the human pathogen Porphyromonas gingivalis. The microbial profile of the supragingival plaque of the abutting tooth to the ulcer revealed similar pathogens. This study showed that in dogs with stomatitis, the mucosal ulcer is inhabited by a unique, species-specific bacterial community and suggests significant differences between the oral mucosa of healthy dogs, dogs with severe periodontal disease, or dogs with oral mucosal tumors. Based on our results, full-mouth, tooth extraction may not be the optimal treatment of the disease. Localization of the First Mandibular Molar Roots in Relationship to the Mandibular Canal in Small Breed Dogs—A Tomography Imaging Study Chia H, Taney K, Hoover D, Robertson JB, VillamizarMartinez LA. Front Vet Sci. 2021 May 12;8:684763 The intimate relationship between the mandibular canal (MC) and the first mandibular molar tooth presents challenges when performing dentoalveolar surgical procedures due to the probability of causing iatrogenic injury to the inferior alveolar neurovascular bundle. Superimposition between the MC and the first molar (M1) tooth roots is often observed on intraoral dental radiographs in small breed dogs. However, due to the radiograph’s bidimensional nature, it is impossible to determine the buccal or lingual l
{"title":"Abstracts from other journals","authors":"Anderson","doi":"10.1177/08987564211048659","DOIUrl":"https://doi.org/10.1177/08987564211048659","url":null,"abstract":"s From Other Journals Characterization of the Oral Microbiome in Canine Chronic Ulcerative Stomatitis Anderson JG, Paster BJ, Kokaras A, Chen T. J Immun Res. 2021;7(1):1037 Canine chronic ulcerative stomatitis is a debilitating, oral mucosal disorder of dogs. A commonly held hypothesis for pathogenesis is that bacterial plaque on tooth surfaces is responsible for the ulcerative mucosal lesions. As such, therapy has focused on fullmouth, tooth extraction. Recent studies revealed a unique leukocyte profile in canine ulcerative stomatitis that is amenable to immune modulating therapy. What remains unknown is the role bacteria may play in dysbiosis and immune-inflammatory mechanisms. The microbiota of canine ulcerative stomatitis has not been characterized. Aims of the present study include determination of themicrobiomeofmucosal lesions in canine ulcerative stomatitis and that of the supragingival plaque of the opposing tooth. Themicrobiota of these surfaceswas compared to healthymucosa in the canine ulcerative stomatitis patient, and three non-stomatitis control patients. Our hypothesis was that specific microbial species or complexes are associated with ulcerative stomatitis. DNA from 100 clinical samples was evaluated using Next Generation Sequencing methods and was analyzed using LDA Effect Size and the non-parametric factorial Kruskal-Wallis sum-rank test. Statistically significant differences in species were determined frommucosal ulcers versus normal sites in ulcerative stomatitis patients. Species that were more prevalent on the ulcer lesions included putative periodontal pathogens, such as a Tannerella forsythia-like phylotype and Porphyromonas gingivicanis, a species related to the human pathogen Porphyromonas gingivalis. The microbial profile of the supragingival plaque of the abutting tooth to the ulcer revealed similar pathogens. This study showed that in dogs with stomatitis, the mucosal ulcer is inhabited by a unique, species-specific bacterial community and suggests significant differences between the oral mucosa of healthy dogs, dogs with severe periodontal disease, or dogs with oral mucosal tumors. Based on our results, full-mouth, tooth extraction may not be the optimal treatment of the disease. Localization of the First Mandibular Molar Roots in Relationship to the Mandibular Canal in Small Breed Dogs—A Tomography Imaging Study Chia H, Taney K, Hoover D, Robertson JB, VillamizarMartinez LA. Front Vet Sci. 2021 May 12;8:684763 The intimate relationship between the mandibular canal (MC) and the first mandibular molar tooth presents challenges when performing dentoalveolar surgical procedures due to the probability of causing iatrogenic injury to the inferior alveolar neurovascular bundle. Superimposition between the MC and the first molar (M1) tooth roots is often observed on intraoral dental radiographs in small breed dogs. However, due to the radiograph’s bidimensional nature, it is impossible to determine the buccal or lingual l","PeriodicalId":19400,"journal":{"name":"Oil & Fat Industries","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81267122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. D. Brown, J. Boggs, R. Hilderbrandt, K. Lim, I. Mills, E. Niktin, M. Palmer
{"title":"Foe","authors":"R. D. Brown, J. Boggs, R. Hilderbrandt, K. Lim, I. Mills, E. Niktin, M. Palmer","doi":"10.1515/iupac.68.0928","DOIUrl":"https://doi.org/10.1515/iupac.68.0928","url":null,"abstract":"","PeriodicalId":19400,"journal":{"name":"Oil & Fat Industries","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76667781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
There is no single, neat statutory provision labeled the “right to explanation” in Europe’s new General Data Protection Regulation (GDPR). But nor is such a right illusory. Responding to two prominent papers that, in turn, conjure and critique the right to explanation in the context of automated decision-making, we advocate a return to the text of the GDPR. Articles 13-15 provide rights to “meaningful information about the logic involved” in automated decisions. This is a right to explanation, whether one uses the phrase or not. The right to explanation should be interpreted functionally, flexibly, and should, at a minimum, enable a data subject to exercise his or her rights under the GDPR and human rights law.
{"title":"\"Meaningful Information\" and the Right to Explanation","authors":"Andrew D. Selbst, Julia E. Powles","doi":"10.1093/IDPL/IPX022","DOIUrl":"https://doi.org/10.1093/IDPL/IPX022","url":null,"abstract":"There is no single, neat statutory provision labeled the “right to explanation” in Europe’s new General Data Protection Regulation (GDPR). But nor is such a right illusory. \u0000Responding to two prominent papers that, in turn, conjure and critique the right to explanation in the context of automated decision-making, we advocate a return to the text of the GDPR. \u0000Articles 13-15 provide rights to “meaningful information about the logic involved” in automated decisions. This is a right to explanation, whether one uses the phrase or not. \u0000The right to explanation should be interpreted functionally, flexibly, and should, at a minimum, enable a data subject to exercise his or her rights under the GDPR and human rights law.","PeriodicalId":19400,"journal":{"name":"Oil & Fat Industries","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90734327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"What is the cost?","authors":"D. Gaboriau","doi":"10.1007/BF02564101","DOIUrl":"https://doi.org/10.1007/BF02564101","url":null,"abstract":"","PeriodicalId":19400,"journal":{"name":"Oil & Fat Industries","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81983569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Avoiding the obvious","authors":"S. L. Murphy, K. D. Sibley","doi":"10.1038/BIOE.2008.12","DOIUrl":"https://doi.org/10.1038/BIOE.2008.12","url":null,"abstract":"","PeriodicalId":19400,"journal":{"name":"Oil & Fat Industries","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2002-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78919793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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