Pub Date : 2024-05-24DOI: 10.1097/01.aoa.0001015992.38242.30
C. Tan, H. Tan, R. Sultana, M. Meaney, M. Ling Kee, B. Sng
(J Clin Anesth. 2022;83:110978 | https://doi.org/10.1016/j.jclinane.2022.110978|) Persistent postpartum pain poses significant societal and health care challenges. It is defined by the International Association for the Study of Pain as pain lasting beyond 3 months after tissue injury, affecting up to 30% of postpartum women. Research primarily focuses on risk factors for persistent pain, including severe acute postpartum pain, psychological factors, and social deprivation. However, there is a lack of investigation into subacute pain after childbirth (lasting 4 wk to 3 mo). A previous study identified some risk factors for subacute pain, but the relationship between acute postpartum pain and subacute pain remains unexplored. This study aims to investigate these associations and explore potential interventions by anesthesiologists.
{"title":"Association of Pain, Analgesic, Psychological, and Socioeconomic Factors With Subacute Pain After Childbirth: A Prospective Cohort Study","authors":"C. Tan, H. Tan, R. Sultana, M. Meaney, M. Ling Kee, B. Sng","doi":"10.1097/01.aoa.0001015992.38242.30","DOIUrl":"https://doi.org/10.1097/01.aoa.0001015992.38242.30","url":null,"abstract":"(J Clin Anesth. 2022;83:110978 | https://doi.org/10.1016/j.jclinane.2022.110978|)\u0000 Persistent postpartum pain poses significant societal and health care challenges. It is defined by the International Association for the Study of Pain as pain lasting beyond 3 months after tissue injury, affecting up to 30% of postpartum women. Research primarily focuses on risk factors for persistent pain, including severe acute postpartum pain, psychological factors, and social deprivation. However, there is a lack of investigation into subacute pain after childbirth (lasting 4 wk to 3 mo). A previous study identified some risk factors for subacute pain, but the relationship between acute postpartum pain and subacute pain remains unexplored. This study aims to investigate these associations and explore potential interventions by anesthesiologists.","PeriodicalId":19432,"journal":{"name":"Obstetric Anesthesia Digest","volume":"5 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141100656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-24DOI: 10.1097/01.aoa.0001015956.32254.7b
D. Villela-Franyutti, K. Hackett, M. Lumbreras-Marquez
(Int J Obstet Anesth. 2023;55:103893/https://doi.org/10.1016/j.ijoa.2023.103893/) Postpartum hemorrhage (PPH) is a significant contributor to preventable maternal morbidity and mortality, necessitating a comprehensive, interdisciplinary approach. Recognizing the urgency, the American College of Obstetricians and Gynecologists advocates adopting PPH bundles to ensure prompt identification and intervention. Obstetric anesthesiologists, possessing expertise in critical care and transfusion, are integral to the resuscitation efforts in PPH. Nevertheless, their involvement in implementing PPH bundles is inconsistent, prompting the need for a more dedicated focus on predelivery risk assessment, early recognition, and institutional protocol development.
{"title":"Incorporating a Postpartum Hemorrhage Bundle on the Labor and Delivery Unit: A State-Wide Survey of Anesthesiologists in Massachusetts","authors":"D. Villela-Franyutti, K. Hackett, M. Lumbreras-Marquez","doi":"10.1097/01.aoa.0001015956.32254.7b","DOIUrl":"https://doi.org/10.1097/01.aoa.0001015956.32254.7b","url":null,"abstract":"(Int J Obstet Anesth. 2023;55:103893/https://doi.org/10.1016/j.ijoa.2023.103893/)\u0000 Postpartum hemorrhage (PPH) is a significant contributor to preventable maternal morbidity and mortality, necessitating a comprehensive, interdisciplinary approach. Recognizing the urgency, the American College of Obstetricians and Gynecologists advocates adopting PPH bundles to ensure prompt identification and intervention. Obstetric anesthesiologists, possessing expertise in critical care and transfusion, are integral to the resuscitation efforts in PPH. Nevertheless, their involvement in implementing PPH bundles is inconsistent, prompting the need for a more dedicated focus on predelivery risk assessment, early recognition, and institutional protocol development.","PeriodicalId":19432,"journal":{"name":"Obstetric Anesthesia Digest","volume":"5 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141101308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-24DOI: 10.1097/01.aoa.0001016100.13340.f5
A.J. Lee, A. Palanisamy
(Anaesthesia. 2023;78:799–802) The majority of studies on ethnic disparities in health care environments originate in the United States, where access to care and other factors make the health care experience different for every individual. It has been unclear whether these disparities exist in countries with a more consistently available health care system, such as the United Kingdom. This article comments on a recent study about ethnic disparities in the obstetric anesthesia population in the United Kingdom.
{"title":"Ethnic Disparities in Obstetric Anesthesia Care in England: Parallels and Paradoxes With Care in the United States","authors":"A.J. Lee, A. Palanisamy","doi":"10.1097/01.aoa.0001016100.13340.f5","DOIUrl":"https://doi.org/10.1097/01.aoa.0001016100.13340.f5","url":null,"abstract":"(Anaesthesia. 2023;78:799–802)\u0000 The majority of studies on ethnic disparities in health care environments originate in the United States, where access to care and other factors make the health care experience different for every individual. It has been unclear whether these disparities exist in countries with a more consistently available health care system, such as the United Kingdom. This article comments on a recent study about ethnic disparities in the obstetric anesthesia population in the United Kingdom.","PeriodicalId":19432,"journal":{"name":"Obstetric Anesthesia Digest","volume":"81 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141101710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-24DOI: 10.1097/01.aoa.0001016060.91416.b8
M.G. Gonzalez, M. Barske, K.B. Kjellsson, K. Saboda, H. Reed, M.G. Hill
(Aust N Z J Obstet Gynaecol. 2023;63:516–520) The prevalence of cesarean deliveries (CD) has surged in recent decades, paralleling an uptick in medical complications during pregnancy linked to delayed childbearing and rising obesity rates. Consequently, post-CD wound complications have become a significant health concern. Mitigating these complications is a priority, with various wound vacuum systems available. While concerns persist about their effectiveness compared to standard treatments, some evidence suggests modest benefits, particularly in nonobstetric settings. The PICO wound vacuum system has shown promise for clean, noninfected surgical wounds, including cesarean incisions, though data is mainly from small trials or retrospective cohorts. Our study explores the use of PICO in preventing wound infections and breakdown in women with risk factors for complications postcesarean delivery.
(Aust N Z J Obstet Gynaecol. 2023; 63:516-520)近几十年来，剖宫产（CD）的发病率激增，与此同时，与生育延迟和肥胖率上升有关的孕期医疗并发症也在增加。因此，剖腹产后伤口并发症已成为一个重要的健康问题。缓解这些并发症是当务之急，目前有多种伤口真空系统可供选择。虽然与标准治疗方法相比，这些系统的效果仍令人担忧，但一些证据表明，它们的效果并不明显，尤其是在非产科环境中。PICO 伤口真空系统在清洁、未感染的手术伤口（包括剖宫产切口）方面显示出了良好的前景，但数据主要来自小型试验或回顾性队列。我们的研究探讨了 PICO 在预防具有剖宫产后并发症风险因素的产妇伤口感染和破裂方面的应用。
{"title":"Topical Negative Pressure Wound Therapy to Prevent Wound Complications Following Cesarean Delivery in High-Risk Obstetric Patients: A Randomized Controlled Trial","authors":"M.G. Gonzalez, M. Barske, K.B. Kjellsson, K. Saboda, H. Reed, M.G. Hill","doi":"10.1097/01.aoa.0001016060.91416.b8","DOIUrl":"https://doi.org/10.1097/01.aoa.0001016060.91416.b8","url":null,"abstract":"(Aust N Z J Obstet Gynaecol. 2023;63:516–520)\u0000 The prevalence of cesarean deliveries (CD) has surged in recent decades, paralleling an uptick in medical complications during pregnancy linked to delayed childbearing and rising obesity rates. Consequently, post-CD wound complications have become a significant health concern. Mitigating these complications is a priority, with various wound vacuum systems available. While concerns persist about their effectiveness compared to standard treatments, some evidence suggests modest benefits, particularly in nonobstetric settings. The PICO wound vacuum system has shown promise for clean, noninfected surgical wounds, including cesarean incisions, though data is mainly from small trials or retrospective cohorts. Our study explores the use of PICO in preventing wound infections and breakdown in women with risk factors for complications postcesarean delivery.","PeriodicalId":19432,"journal":{"name":"Obstetric Anesthesia Digest","volume":"9 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141098919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-24DOI: 10.1097/01.aoa.0001016108.83972.5a
E. Roofthooft, N. Filetici, M. Van Houwe, P. Van Houwe, A. Barbe, S. Fieuws, S. Rex, C.A. Wong, M. Van de Velde
(Anaesthesia. 2023;78(9):1129–1138) Neuraxial labor analgesia is a well-established and effective method for managing pain during labor. The initiation of analgesia through epidural or combined spinal-epidural methods can be followed by various maintenance techniques, including continuous epidural infusion, manual intermittent boluses, patient-controlled epidural analgesia (PCEA), programmed intermittent epidural bolus (PIEB), or a combination of these approaches. Adding PCEA to a continuous infusion was long-favored, demonstrating benefits such as reduced breakthrough pain incidents, lower local anesthetic consumption without compromising efficacy, and heightened patient satisfaction compared with continuous epidural infusion.
{"title":"High-Volume Patient-Controlled Epidural Versus Programmed Intermittent Epidural Bolus for Labor Analgesia: A Randomized Controlled Study","authors":"E. Roofthooft, N. Filetici, M. Van Houwe, P. Van Houwe, A. Barbe, S. Fieuws, S. Rex, C.A. Wong, M. Van de Velde","doi":"10.1097/01.aoa.0001016108.83972.5a","DOIUrl":"https://doi.org/10.1097/01.aoa.0001016108.83972.5a","url":null,"abstract":"(Anaesthesia. 2023;78(9):1129–1138)\u0000 Neuraxial labor analgesia is a well-established and effective method for managing pain during labor. The initiation of analgesia through epidural or combined spinal-epidural methods can be followed by various maintenance techniques, including continuous epidural infusion, manual intermittent boluses, patient-controlled epidural analgesia (PCEA), programmed intermittent epidural bolus (PIEB), or a combination of these approaches. Adding PCEA to a continuous infusion was long-favored, demonstrating benefits such as reduced breakthrough pain incidents, lower local anesthetic consumption without compromising efficacy, and heightened patient satisfaction compared with continuous epidural infusion.","PeriodicalId":19432,"journal":{"name":"Obstetric Anesthesia Digest","volume":"3 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141100413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-24DOI: 10.1097/01.aoa.0001016116.81658.39
H.S. Tan, J.J.I. Chan, T.T. Oh, M.J. Lim, C.W. Tan, R. Sultana, B. Sng
(Eur J Anaesthesiol. 2023;40(9):710–714) Traditional neuraxial procedures, relying on palpation, face a notable 27% failure rate. The integration of preprocedure ultrasonography offers a potential solution, although challenges arise in obese parturients, resulting in a 76% procedural success rate compared to over 90% in nonobese counterparts.
{"title":"Automated Identification of Landmarks During Preprocedure Lumbar Ultrasound for Spinal Anesthesia in Obese Parturients: A Prospective Cohort Study","authors":"H.S. Tan, J.J.I. Chan, T.T. Oh, M.J. Lim, C.W. Tan, R. Sultana, B. Sng","doi":"10.1097/01.aoa.0001016116.81658.39","DOIUrl":"https://doi.org/10.1097/01.aoa.0001016116.81658.39","url":null,"abstract":"(Eur J Anaesthesiol. 2023;40(9):710–714)\u0000 Traditional neuraxial procedures, relying on palpation, face a notable 27% failure rate. The integration of preprocedure ultrasonography offers a potential solution, although challenges arise in obese parturients, resulting in a 76% procedural success rate compared to over 90% in nonobese counterparts.","PeriodicalId":19432,"journal":{"name":"Obstetric Anesthesia Digest","volume":"13 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141102748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-24DOI: 10.1097/01.aoa.0001016092.68961.48
T.T.M. Lee, C. Collett, S. Bergford, S. Hartnell, H. R. Murphy, E. Scott, R. S. Lindsay, K. F. Hunt, D. R. McCance, K. Barnard-Kelly, D. Rankin, J. Lawton, R. Reynolds, E. Flanagan, M. Hammond, L. Shepstone, M. Wilinska, J. Sibayan, C. Kollman, R. Beck, R. Hovorka
(N Engl J Med. 2023;389:1566–1578) Type 1 diabetes often causes significant complications both during pregnancy and immediately after delivery for both mother and infant. This makes glycemic control during pregnancy for these women of utmost importance for their health and that of their baby. Several therapies have been introduced for pregnancies complicated by type 1 diabetes, and one that is relatively new is hybrid closed loop therapy; because of its recent development, the efficacy of this treatment is still unclear. This study was designed to test if the initiation of hybrid closed loop therapy before 16 weeks of gestation would improve glucose levels during pregnancy. The primary outcome for this study was the percentage of time that glucose levels were within the pregnancy-specific target range of 63 to 140 mg per deciliter.
{"title":"Automated Insulin Delivery in Women With Pregnancy Complicated by Type 1 Diabetes","authors":"T.T.M. Lee, C. Collett, S. Bergford, S. Hartnell, H. R. Murphy, E. Scott, R. S. Lindsay, K. F. Hunt, D. R. McCance, K. Barnard-Kelly, D. Rankin, J. Lawton, R. Reynolds, E. Flanagan, M. Hammond, L. Shepstone, M. Wilinska, J. Sibayan, C. Kollman, R. Beck, R. Hovorka","doi":"10.1097/01.aoa.0001016092.68961.48","DOIUrl":"https://doi.org/10.1097/01.aoa.0001016092.68961.48","url":null,"abstract":"(N Engl J Med. 2023;389:1566–1578)\u0000 Type 1 diabetes often causes significant complications both during pregnancy and immediately after delivery for both mother and infant. This makes glycemic control during pregnancy for these women of utmost importance for their health and that of their baby. Several therapies have been introduced for pregnancies complicated by type 1 diabetes, and one that is relatively new is hybrid closed loop therapy; because of its recent development, the efficacy of this treatment is still unclear. This study was designed to test if the initiation of hybrid closed loop therapy before 16 weeks of gestation would improve glucose levels during pregnancy. The primary outcome for this study was the percentage of time that glucose levels were within the pregnancy-specific target range of 63 to 140 mg per deciliter.","PeriodicalId":19432,"journal":{"name":"Obstetric Anesthesia Digest","volume":"65 17","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141102139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-24DOI: 10.1097/01.aoa.0001016120.15111.ba
T. Hung, Y. Huang, Y. Lin
(J Clin Anesth. 2022;80:110786 | https://doi.org/10.1016/j.jclinane.2022.110786.) In 2015, global cesarean deliveries (CD) reached 29.7 million. While evidence indicates comparable outcomes between general and regional anesthesia, the latter is preferred for elective CD due to benefits like reduced fetal exposure to anesthetics. Intrathecal bupivacaine is effective but can cause adverse effects like hypotension. Low-dose bupivacaine minimizes risks but may require additional analgesics, potentially leading to general anesthesia. Various adjuvants, such as opioids and alpha-2-agonists, enhance spinal anesthesia quality, each with unique effects. Intrathecal midazolam, studied since the 1980s, has shown promise in reducing nausea and vomiting. However, its safety for neonates and effectiveness in cesarean delivery remained uncertain. This systematic review and meta-analysis aimed to fill this gap by comprehensively assessing the efficacy and safety of adding intrathecal midazolam to spinal anesthesia for CD in healthy pregnant patients, considering maternal and neonatal outcomes.
{"title":"Maternal and Neonatal Outcomes With the Addition of Intrathecal Midazolam as an Adjuvant to Spinal Anesthesia in Cesarean Delivery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials","authors":"T. Hung, Y. Huang, Y. Lin","doi":"10.1097/01.aoa.0001016120.15111.ba","DOIUrl":"https://doi.org/10.1097/01.aoa.0001016120.15111.ba","url":null,"abstract":"(J Clin Anesth. 2022;80:110786 | https://doi.org/10.1016/j.jclinane.2022.110786.)\u0000 In 2015, global cesarean deliveries (CD) reached 29.7 million. While evidence indicates comparable outcomes between general and regional anesthesia, the latter is preferred for elective CD due to benefits like reduced fetal exposure to anesthetics. Intrathecal bupivacaine is effective but can cause adverse effects like hypotension. Low-dose bupivacaine minimizes risks but may require additional analgesics, potentially leading to general anesthesia. Various adjuvants, such as opioids and alpha-2-agonists, enhance spinal anesthesia quality, each with unique effects. Intrathecal midazolam, studied since the 1980s, has shown promise in reducing nausea and vomiting. However, its safety for neonates and effectiveness in cesarean delivery remained uncertain. This systematic review and meta-analysis aimed to fill this gap by comprehensively assessing the efficacy and safety of adding intrathecal midazolam to spinal anesthesia for CD in healthy pregnant patients, considering maternal and neonatal outcomes.","PeriodicalId":19432,"journal":{"name":"Obstetric Anesthesia Digest","volume":"7 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141100871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-24DOI: 10.1097/01.aoa.0001016132.17694.bd
J. Bamber
(Anaesthesia. 2023;78(9):1058–1061) The National Institute for Health and Care Excellence (NICE) characterizes current UK postnatal care as a “Cinderella service,” marked by insufficient provisions and only 8.5% of the maternity care budget. Despite 97% of births occurring in hospitals, the average postnatal stay of 1.5 days is the shortest among high-income countries. While most women find their stay appropriate, empowering them to choose its duration enhances satisfaction without adverse effects.
{"title":"Why Anesthetists Should Care About Postnatal Care","authors":"J. Bamber","doi":"10.1097/01.aoa.0001016132.17694.bd","DOIUrl":"https://doi.org/10.1097/01.aoa.0001016132.17694.bd","url":null,"abstract":"(Anaesthesia. 2023;78(9):1058–1061)\u0000 The National Institute for Health and Care Excellence (NICE) characterizes current UK postnatal care as a “Cinderella service,” marked by insufficient provisions and only 8.5% of the maternity care budget. Despite 97% of births occurring in hospitals, the average postnatal stay of 1.5 days is the shortest among high-income countries. While most women find their stay appropriate, empowering them to choose its duration enhances satisfaction without adverse effects.","PeriodicalId":19432,"journal":{"name":"Obstetric Anesthesia Digest","volume":"8 36","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141098686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-24DOI: 10.1097/01.aoa.0001016048.40147.f4
C.A. Cluver, S.P. Walker
(Lancet. 2023;402(10399):350–352) It is well known in the field that pre-eclampsia is a large contributor to maternal and perinatal morbidity and mortality, with the burden disproportionately falling on lower income countries; much of the research surrounding pre-eclampsia and its management has been done in high-income countries, even though the disease burden in these countries is felt less severely. This article is a commentary arguing for more research in this area particularly for the settings in which people are most affected.
{"title":"Early Delivery for Pre-eclampsia Might Save Lives in Low-Income and Middle-Income Settings","authors":"C.A. Cluver, S.P. Walker","doi":"10.1097/01.aoa.0001016048.40147.f4","DOIUrl":"https://doi.org/10.1097/01.aoa.0001016048.40147.f4","url":null,"abstract":"(Lancet. 2023;402(10399):350–352)\u0000 It is well known in the field that pre-eclampsia is a large contributor to maternal and perinatal morbidity and mortality, with the burden disproportionately falling on lower income countries; much of the research surrounding pre-eclampsia and its management has been done in high-income countries, even though the disease burden in these countries is felt less severely. This article is a commentary arguing for more research in this area particularly for the settings in which people are most affected.","PeriodicalId":19432,"journal":{"name":"Obstetric Anesthesia Digest","volume":"84 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141101807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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