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Phase Transition of Aligned two Higgs Doublets Model in the Cornwall-Jackiw-Tomboulis Formalism 康沃尔-杰克维-通布里斯形式主义中对齐的双希格斯模型的相变
Pub Date : 2024-02-20 DOI: 10.53747/nst.v13i1.406
Tuan Anh Nguyen, Thanh Tam Dinh, Thi Minh Hue Dang
Using the Cornwall-Jackiw-Tomboulis formalism at finite temperature, we consider the phase transition of the aligned two Higgs doublet model in the two-loop double-bubble contribution. The results show that the system obeys a first-order phase transition.
我们利用有限温度下的康沃尔-杰克-汤布利斯(Cornwall-Jackiw-Tomboulis)形式主义,考虑了双环双泡贡献中对齐的双希格斯双特模型的相变。结果表明,该系统服从一阶相变。
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引用次数: 0
Application of internal mono standard neutron activation analysis method in elemental analysis of car glasses for forensic study 内部单标准中子活化分析法在法医研究汽车玻璃元素分析中的应用
Pub Date : 2024-02-20 DOI: 10.53747/nst.v12i4.384
Tuan Anh Tran, Q. Tran, M. Ho, V. Ho, Van Cuong Trinh, Thi Tho Nguyen
The use of nuclear techniques for elemental analysis has been successfully developed in many laboratories in the IAEA Member States, including Vietnam. Nuclear techniques have also been proven to be extremely powerful in provenancing samples relevant to forensics. In the framework of the CRP project on Enhancing Nuclear Analytical Techniques to Meet the Needs of Forensic Sciences (IAEA CRP F11021), a total of 19 elemental concentrations in 48 car glass samples has been determined by the internal monostandard neutron activation analysis (IM-NAA) method. In this work, obtained results from the statical analysis indicated that rare earth elements (La, Ce, Sm, Eu, Tb, Yb), transition (Sc, Mn, Fe, Co, Zn) and major (Al, Na, Fe, Ca) elements play a significant role in the group study of car glasses.
包括越南在内的国际原子能机构成员国的许多实验室已成功开发了使用核技术进行元素分析的方法。事实证明,核技术在验证与法医学有关的样本方面也极为强大。在 "加强核分析技术以满足法医学需求 "CRP 项目(IAEA CRP F11021)框架内,采用内部单标准中子活化分析(IM-NAA)方法测定了 48 个汽车玻璃样品中的 19 种元素浓度。在这项工作中,静态分析的结果表明,稀土元素(La、Ce、Sm、Eu、Tb、Yb)、过渡元素(Sc、Mn、Fe、Co、Zn)和主要元素(Al、Na、Fe、Ca)在汽车玻璃的组研究中发挥了重要作用。
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引用次数: 0
Development of Brain MRI Image Segmentation program using UNET++ network for radiosurgery planning 利用 UNET++ 网络开发脑磁共振成像图像分割程序,用于放射外科手术规划
Pub Date : 2024-02-20 DOI: 10.53747/nst.v13i1.398
Bui Ha, Tuấn Kiên Nguyễn, Dương Trần, Ngọc Toàn Trần, Quang Tuấn Hồ, Thu Trang Vũ
Image processing is one of the most important and widely used techniques in the medical field. Magnetic Resonance Imaging (MRI) can provide diagnostic images with high contrast and high resolution, especially for low-density tissue. Therefore, applications to support tumor prediction are researched and developed. In this paper, we use applied artificial intelligence to identify and detect tumors using the UNET ++ deep learning model, which achieved results with a recognition rate of about 80%. The results for a great deal of built-in functionality in the built-in physician support software system in practice.
图像处理是医学领域最重要、应用最广泛的技术之一。磁共振成像(MRI)可提供高对比度和高分辨率的诊断图像,特别是针对低密度组织。因此,支持肿瘤预测的应用得到了研究和开发。本文使用 UNET ++ 深度学习模型,利用应用人工智能识别和检测肿瘤,取得了识别率约为 80% 的成果。该结果为内置的医生支持软件系统在实践中提供了大量的内置功能。
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引用次数: 0
Irradiation-induced Maillard reaction with glucosamine: an advance strategy to modify chitosan 辐照诱导的葡萄糖胺马氏反应:改性壳聚糖的先进策略
Pub Date : 2024-02-20 DOI: 10.53747/nst.v12i4.385
Anh Quoc Le, Van Phu Dang, Ngoc Duy Nguyen, Chi Thuan Nguyen, Q. Nguyen, Dai Nghiep Ngo
In this study, Maillard reaction with glucosamine (GA) induced by gamma irradiation was applied for chitosan (CT) and oligochitosan (OC) to improve the solution stability and antibacterial activity under alkaline condition. The mixture solutions of CT and/or OC with GA were irradiated at the dose of 25 kGy to form the Maillard reaction products (MRPs) respectively. The formations of MRPs were determined by spectrophotometric analyses at the wavelength of 284 nm and 420 nm. The improvement effect caused by the Maillard reaction on the stability of CT and OC solutions in alkaline condition was evaluated through the increase of pH value at the precipitation point of the solutions before and after irradiation. The antibacterial activity of the solutions against Escherichia coli was also investigated. The results showed that the CT-GA MRPs and OC-GA MRPs solutions could be remain their stability at pH 7, and the pH values at the precipitation point were 7.4 and 11.5 respectively. Moreover, at pH 7, the MRPs solutions exhibited high antibacterial activity with the reduction of ~ 4 log CFU/ml over control sample. Furthermore, 5-hydroxymethylfurfural (5-HMF), a known cytotoxic product formed by heat-induced Maillard reaction was not detected in both irradiated CT-GA and OC-GA solution. These results prove that the irradiation-induced Maillard reaction is an effective strategy to modify chitosan, and the MPRs of CT/OS with GA had a great potential to replace synthesis additives as a natural preservative for food applications
本研究采用伽马辐照诱导壳聚糖(CT)和低聚壳聚糖(OC)与氨基葡萄糖(GA)发生马氏反应,以提高其在碱性条件下的溶液稳定性和抗菌活性。将壳聚糖和/或低聚壳聚糖与 GA 的混合溶液分别置于 25 kGy 的剂量下进行辐照,以形成麦拉德反应产物(MRPs)。MRPs 的形成是通过 284 纳米和 420 纳米波长的分光光度法测定的。马氏反应对 CT 和 OC 溶液在碱性条件下稳定性的改善作用是通过辐照前后溶液沉淀点 pH 值的增加来评估的。此外,还研究了溶液对大肠杆菌的抗菌活性。结果表明,CT-GA MRPs 和 OC-GA MRPs 溶液在 pH 值为 7 时仍能保持稳定,沉淀点的 pH 值分别为 7.4 和 11.5。此外,在 pH 值为 7 时,MRPs 溶液表现出较高的抗菌活性,与对照样品相比,可减少约 4 log CFU/ml。此外,在辐照 CT-GA 和 OC-GA 溶液中均未检测到 5-羟甲基糠醛(5-HMF),这是一种由热诱导的 Maillard 反应生成的已知细胞毒性产物。这些结果证明,辐照诱导的马氏反应是对壳聚糖进行改性的一种有效策略,CT/OS 与 GA 的 MPRs 有很大潜力取代合成添加剂,成为食品应用中的天然防腐剂。
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引用次数: 0
Characteristics of the reference X-ray narrow-spectrum series at SSDL of Institute for Nuclear Science and Technology 核科学与技术研究所 SSDL 参考 X 射线窄谱系列的特征
Pub Date : 2024-02-20 DOI: 10.53747/nst.v12i4.387
Thi My Linh Dang, Ngoc Quynh Nguyen, Duc-Ky Bui, Thi Nhung Duong, Quang Tuan Ho, Van Trieu Duong, Thanh Ha Tran, Thi Anh Duong Bui, Bao Ngoc Pham
This paper presents the characteristics of the reference X-ray narrow-spectrum series used in the Secondary Standard Dosimetry Laboratory (SSDL) at Institute for Nuclear Science and Technology (INST) with X-ray beam irradiator. In order to perform calibration works, it is highly important to verify the characteristics and qualities of reference X-ray beam recommended by the International Standardization Organization (ISO) 4037:2019. The characteristics of the X-ray beams in terms of the half-value layer, homogeneity coefficient and the air kerma rate are determined for the narrow-spectrum series in the 40 and 150 keV range. The related dosimetric quantities such as the ambient dose equivalent and personal dose equivalent also determined. The experimental values are well consistent with the recommended values of the ISO 4037 criteria. It implies that the reference X-ray narrow-spectrum series (N-series) can be applied in calibration works of X-ray measuring devices used in radiation safety assessment.
本文介绍了核科学与技术研究所二级标准剂量测定实验室(SSDL)使用的 X 射线束辐照装置的参考 X 射线窄谱系列的特性。为了进行校准工作,验证国际标准化组织(ISO)4037:2019 推荐的参考 X 射线束的特性和质量非常重要。针对 40 和 150 千伏范围内的窄光谱系列,确定了 X 射线束在半值层、均匀性系数和空气开玛率方面的特性。同时还测定了相关的剂量测定量,如环境剂量当量和个人剂量当量。实验值与 ISO 4037 标准的推荐值完全一致。这意味着参考 X 射线窄谱系列(N 系列)可用于辐射安全评估中 X 射线测量设备的校准工作。
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引用次数: 0
Study of image reconstruction method for 2D gamma scan technique by anti-aliasing line "Xiaolin Wu" algorithm combined with simultaneous algebraic reconstruction algorithms and testing on MCNP simulation data 抗锯齿线 "Xiaolin Wu "算法与同步代数重建算法相结合的二维伽马扫描技术图像重建方法研究及 MCNP 仿真数据测试
Pub Date : 2024-02-20 DOI: 10.53747/nst.v12i4.397
Chau Nguyen Thanh, Thao Huong Giang Le, Ngoc Nhat Anh Nguyen, Van Chuan Nguyen, Tien Thanh Pham
Gamma scanning technique is known to be an effective method for survey the condition of distillation columns in petrochemical refineries and has been widely applied. The result of the gamma scanning is a 1-dimensional graph showing the transmittance counts according to the height of the column. To illuminate the important phenomena occurring on the tray such as foaming; flooding; weeping due to valve failure on the tray needs experienced people and the interpretation results are still quite qualitative. The method of 2-D gamma scanning and reconstruction (2D Tomography), which has just appeared in the world in recent years, is considered as a potential method to help detect the above phenomena. This report presents the two-dimensional gamma scanning configuration, mathematical calculation and noise processing methods by using the combination of Xiaolin Wu’s line drawing algorithm with simultaneous algebraic reconstruction algorithm (SART) based on data from Monte Carlo simulation.
众所周知,伽马扫描技术是勘测石化炼油厂蒸馏塔状况的有效方法,并已得到广泛应用。伽马扫描的结果是根据塔的高度显示透射率计数的一维图形。要揭示塔盘上发生的重要现象,如起泡、溢流、因塔盘阀门故障而导致的流泪等,需要有经验的人员,而且解释结果仍相当定性。近年来在世界上刚刚出现的二维伽马扫描和重建(二维断层扫描)方法被认为是有助于检测上述现象的一种潜在方法。本报告以蒙特卡罗模拟数据为基础,介绍了吴小林的线描算法与同步代数重建算法(SART)相结合的二维伽马扫描配置、数学计算和噪声处理方法。
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引用次数: 0
Study on preparation of Fe₃O₄@lapatinib nanoparticles for application as a targeted drug delivery system in the treatment of breast cancer 关于制备Fe₃O₄@lapatinib纳米颗粒作为靶向给药系统应用于乳腺癌治疗的研究
Pub Date : 2024-02-20 DOI: 10.53747/nst.v13i1.410
Thanh Minh Pham, Phuoc Minh Thanh Mai, Thi Mai Huong Le, Van Phuc Phan
Systems for targeted drug delivery in the treatment of cancer using nanoparticles are currently of interest to many domestic and foreign scientists. In this work, for application as a target drug delivery system in the treatment of breast cancer Fe3O4@lapatinib nanoparticles were prepared by coprecipitation of solutions of Fe2+ and Fe3+ salts in alkaline, followed by purification in a magnetic separation system. Physicochemical properties of nanoparticles were studied and determined by XRD, TEM, DLS, HPLC, VSM, AAS and zeta potential methods. The results showed that the size of Fe3O4@lapatinib nanoparticles is in the range of 10 to 40 nm, hydrodynamic diameter is 27.4 ± 0.6 nm, saturation magnetization is 39.1 ± 3.1 emu/g,  Fe content is 16.35 ± 0.97 mg/ml, lapatinib content is 8.08 ± 0.06 mg/ml, and the zeta potential is -16.2 ± 1.3 mV. Thus, the obtained Fe3O4@lapatinib nanoparticles are fully suitable for targeted drug delivery in the breast cance treatment
目前,利用纳米粒子靶向给药治疗癌症的系统受到国内外众多科学家的关注。本研究以Fe2+和Fe3+盐溶液在碱性条件下共沉制备了Fe3O4@lapatinib纳米粒子,并在磁分离系统中进行了纯化,以作为治疗乳腺癌的靶向给药系统。通过 XRD、TEM、DLS、HPLC、VSM、AAS 和 zeta 电位法对纳米颗粒的理化性质进行了研究和测定。结果表明,Fe3O4@拉帕替尼纳米粒子的尺寸范围为10至40 nm,流体力学直径为27.4 ± 0.6 nm,饱和磁化率为39.1 ± 3.1 emu/g,铁含量为16.35 ± 0.97 mg/ml,拉帕替尼含量为8.08 ± 0.06 mg/ml,ZETA电位为-16.2 ± 1.3 mV。因此,所获得的Fe3O4@拉帕替尼纳米颗粒完全适用于乳腺癌治疗中的靶向给药。
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引用次数: 0
Effective dose evaluation for external exposure from surface soil by using resrad-onsite code 利用 resrad-onsite 代码评估表层土壤外照射的有效剂量
Pub Date : 2024-02-20 DOI: 10.53747/nst.v13i1.403
Thi Thanh Nga Nguyen, Nhu Sieu Le, Bich Thuy Nguyen
An annual effective dose evaluation from Dong Nai surface soil (45 samples) to humans was carried out in this work. ResRad-Onsite software has been applied to estimate the maximum exposure dose by considering different exposure levels across an area of ​​5905.7 km2 with a topsoil thickness of 20 cm. The calculation grid used in ResRad Onsite software is divided in the form of a circle of radius 3, 5, 10, 20, and 30 km, respectively, calculated from the circle center in terms of 16 wind directions. A high-purity germanium detector (HPGe) was used to determine 238U, 232Th, 226Ra, 137Cs, and 40K isotopes. The range activity concentrations of them were found to be 6.46 ÷ 48.11; 13.95 ÷ 58.75; 5.71 ÷ 35.27; 0.15 ÷ 1.23 and 6.7 ÷ 222; mBq/g, respectively. The isotope 239,240Pu was determined by the radiochemical separation method, measured on the alpha spectrometer system, and the calculated value range is 0.009 ÷ 0.073 mBq/g. The activity of 90Sr was determined by separation technique, measured on a low-background alpha/beta total counting system (MPC 9300) with a calculated value range of 0.10 ÷ 0.83 mBq/g. By ResRad-Onsite code, the external effective dose derived from the ground (excluding Radon’s contribution) is calculated to be 170 ÷ 658 µSv/year with an average value is 368.6 µSv/year. The external dose from the soil is 136.5 µSv/year (accounting for 37%). The results showed that the annual radiation dose distribution derived from the ground equivalent to the average of some different regions in the territory of Vietnam and the world. In addition, the external effective dose from the ResRad-Onsite code tended to be about 1.36 times smaller than the practical measured due to the library’s different dose conversion coefficients.
这项工作对东奈表层土壤(45 个样本)每年对人体的有效剂量进行了评估。在表土厚度为 20 厘米的 5905.7 平方公里区域内,应用 ResRad-Onsite 软件,通过考虑不同的暴露水平来估算最大暴露剂量。ResRad Onsite 软件使用的计算网格以圆圈形式划分,半径分别为 3、5、10、20 和 30 千米,从圆心开始按 16 个风向计算。使用高纯锗探测器(HPGe)测定 238U、232Th、226Ra、137Cs 和 40K 同位素。它们的放射性浓度范围分别为 6.46 ÷ 48.11;13.95 ÷ 58.75;5.71 ÷ 35.27;0.15 ÷ 1.23 和 6.7 ÷ 222;mBq/g。同位素 239、240Pu 的测定采用放射化学分离法,在阿尔法光谱仪系统上测量,计算值范围为 0.009 ÷ 0.073 mBq/g。90Sr 的放射性活度是利用分离技术,在低背景 α/β 总计数系统(MPC 9300)上测定的,计算值范围为 0.10 ÷ 0.83 mBq/g。根据 ResRad-Onsite 代码,计算得出地面的外部有效剂量(不包括氡的贡献)为 170 ÷ 658 µSv/年,平均值为 368.6 µSv/年。来自土壤的外部剂量为 136.5 µSv/年(占 37%)。结果表明,来自地面的年辐射剂量分布相当于越南和世界上一些不同地区的平均值。此外,ResRad-Onsite 代码得出的外部有效剂量往往比实际测量值小约 1.36 倍,原因是该库的剂量转换系数不同。
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引用次数: 0
Research and manufacture of the mini gamma camera using multi-anode photo multiplier tube (Ma-PMT) 利用多阳极光电倍增管(Ma-PMT)研究和制造微型伽马相机
Pub Date : 2024-02-20 DOI: 10.53747/nst.v12i4.375
Bui Ha, Duy Dang Nguyen The, Hoang Nguyen Tuan, Trang Vu Thu, Hai Lai Viet
Gamma camera is an imaging technique that captures gamma radiation emitting from the radiation sources. In this paper, the authors built a Mini-Gamma camera system using a micro photomultiplier tube (µPMT) H12700, signal processing circuit, and control software as self-designed products. The Gamma camera system includes four parts: collimator, scintillator NaI(Tl), µPMT, processing, and controller boards. The electronic system had preamplifiers used to convert negative signals from the µPMT to positive signals, integrators used to sharpen the signal from the preamplifier, and an amplifier circuit to amplify the signal from the preamplifier, a position detection circuit to detect the location of radiation interaction in the crystal. All circuits in the Mini-Gamma camera system are optimized to achieve the best projection image quality. In this paper, the lab-built Mini-Gamma Camera has an energy resolution of 45% at 60 keV gamma rays, the affected field of the camera is 42×48.5 mm2, and the spatial resolution of the image is around 1 mm.
伽马相机是一种捕捉辐射源发出的伽马射线的成像技术。在本文中,作者利用自主设计的微型光电倍增管(µPMT)H12700、信号处理电路和控制软件,构建了一个微型伽马相机系统。伽马相机系统包括四个部分:准直器、闪烁体 NaI(Tl)、µPMT、处理和控制板。电子系统包括用于将来自 µPMT 的负信号转换为正信号的前置放大器、用于锐化来自前置放大器的信号的积分器、放大来自前置放大器的信号的放大电路、用于检测晶体中辐射相互作用位置的位置检测电路。迷你伽马相机系统中的所有电路都经过优化,以获得最佳的投影图像质量。在本文中,实验室制造的微型伽马相机在 60 keV 伽马射线下的能量分辨率为 45%,相机的影响场为 42×48.5 平方毫米,图像的空间分辨率约为 1 毫米。
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引用次数: 0
Self-characterization of irradiation facility using synthetic multi-element standard for determination of k0-factors of seven radionuclides of interest 利用合成多元素标准测定七种相关放射性核素的 k0 因子,实现辐照设施的自我特征描述
Pub Date : 2024-02-20 DOI: 10.53747/nst.v13i1.402
Phonesavanh Lathdavong, Ho Manh Dung, Hồ Văn Doanh, T. Q. Thiện, Trương Trường Sơn
In this study, the k0 factors of 7 short and medium-lived radionuclides (i.e. 66Cu, 52V, 38Cl, 134mCs, 128I, 140La and 56Mn) were experimentally determined at the Dalat nuclear research reactor (DNRR). The synthetic multi-element standard (SMELS) samples were irradiated at Channel 7-1 installed at the DNRR. SMELS Type III contains Au and Zr, thus also allowing the self-characterization of the irradiation facility (i.e. the direct determination of f and a with only this material). The k0 factors of 7 short and medium-lived radionuclides obtained in this work are a good agreement with the reference k0 factors. The ratio values between the experimental and reference k0 values were 66Cu of 1.004, 52V of 1.004, 38Cl of 0.961 and 0.976 (1642.7 keV and 2167.4keV, respectively), 134mCs of 0.831, 128I of 1.022, 140La of 0.936, 0.955 and 0.955 (328.8 keV, 487.0 keV and 1596.2keV, respectively), 56Mn of 0.985 and 0.973 (846.8 keV and 1810.7keV, respectively). The radionuclides range of uncertainty values were lower than 7%. The present result indicates that the k0 factors can be determined by using synthetic multi-element standards (SMELS).
本研究在达叻核研究反应堆(DNRR)对 7 种中短寿命放射性核素(即 66Cu、52V、38Cl、134mCs、128I、140La 和 56Mn)的 k0 因子进行了实验测定。合成多元素标准(SMELS)样品在达叻核研究反应堆安装的 7-1 频道进行辐照。SMELS III 型含有金和锆,因此也允许对辐照设施进行自我表征(即只用这种材料直接测定 f 和 a)。这项工作获得的 7 种中短寿命放射性核素的 k0 因子与参考 k0 因子非常吻合。实验值与参考 k0 值的比值分别为:66Cu 为 1.004、52V 为 1.004、38Cl 为 0.961 和 0.976(分别为 1642.7 keV 和 2167.4 keV)、134mCs 为 0.831、128I 为 1.831(分别为 1642.7 keV 和 2167.4 keV)。831, 128I of 1.022, 140La of 0.936, 0.955 and 0.955 (分别为 328.8 keV, 487.0 keV and 1596.2 keV), 56Mn of 0.985 and 0.973 (分别为 846.8 keV and 1810.7 keV)。放射性核素的不确定值范围均低于 7%。本结果表明,使用合成多元素标准(SMELS)可以确定 k0 因子。
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引用次数: 0
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Nuclear Science and Technology
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