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Iridoschisis: The Shredded Iris 鸢尾花:切碎的鸢尾花
IF 2.8 Q1 OPHTHALMOLOGY Pub Date : 2024-11-01 DOI: 10.1016/j.ogla.2024.04.003
Harshal Sahare MS, FAICO , Darshika Nag MS , Kamala Subramaniam DNB
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引用次数: 0
Evaluation of Research Productivity among Academic Glaucoma Specialists Using the Relative Citation Ratio 利用相对引用比评估学术界青光眼专家的研究生产力。
IF 2.8 Q1 OPHTHALMOLOGY Pub Date : 2024-11-01 DOI: 10.1016/j.ogla.2024.06.004
Matthew N. Henderson MD , Hartej Singh BS , Lucy S. Guan MPH , Ang Li MD , Jonathan L. Prenner MD

Purpose

To provide relative citation ratio (RCR) benchmark data for the field of glaucoma.

Design

Cross-sectional bibliometric analysis.

Subjects

Fellowship-trained glaucoma faculty at Accreditation Council for Graduate Medical Education-accredited institutions.

Methods

Glaucoma faculty were individually indexed using the National Institutes of Health (NIH) iCite website. Publication count, mean RCR score, and weighted RCR score were collected for each author between May and August 2023 and included PubMed-listed articles from 1980 to 2023. Data were compared by sex, career duration, academic rank, and acquisition of a Doctor of Philosophy (PhD).

Main Outcome Measures

Total number of publications, mean RCR value, and weighted RCR value.

Results

Five hundred twenty-six academic glaucoma specialists from 113 institutions were indexed. These physicians produced highly impactful research with a median publication count of 13 (interquartile range [IQR] 4–38), median RCR of 1.41 (IQR 0.97–1.98), and median weighted RCR of 16.89 (4.80–63.39). Academic rank, career duration, and having a PhD were associated with increased publication count, mean RCR, and weighted RCR. Publication count and weighted RCR differed significantly by sex; however, no difference was observed with mean RCR.

Conclusions

Current academic glaucoma specialists have high mean RCR values relative to the NIH standard RCR value of 1. This benchmark data serve as a more accurate gauge of research impact within the glaucoma community and can be used to inform self, institutional, and departmental evaluations. Additionally, the mean RCR may provide an accurate metric for quantifying research productivity among historically underrepresented groups that are disadvantaged by time-dependent factors such as number of publications.

Financial Disclosure(s)

Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.
目的:提供青光眼领域的相对引用比(RCR)基准数据:设计:横断面文献计量分析:方法:在 ACGME 认证机构中接受过研究员培训的青光眼教师:方法:使用美国国立卫生研究院 iCite 网站对青光眼教师进行单独索引。收集了每位作者在2023年5月至8月期间的论文发表数量、平均RCR得分和加权RCR得分,包括1980年至2023年在PubMed上发表的文章。数据按性别、职业生涯持续时间、学术级别和是否获得哲学博士(PhD)进行比较:主要结果指标:论文总数、平均RCR值、加权RCR值:结果:113 个机构的 526 名青光眼学术专家被收录。这些医生的研究具有很高的影响力,发表论文数量中位数为 13 篇(IQR 4-38),RCR 中位数为 1.41(IQR 0.97-1.98),加权 RCR 中位数为 16.89(4.80-63.39)。学术排名、职业生涯持续时间和拥有博士学位与发表论文数量、平均 RCR 和加权 RCR 的增加有关。发表论文数量和加权 RCR 因性别而有显著差异,但平均 RCR 则无差异:与美国国立卫生研究院的标准 RCR 值 1 相比,目前学术界的青光眼专家具有较高的平均 RCR 值。这一基准数据可以更准确地衡量青光眼界的研究影响力,并可用于自我、机构和部门评估。此外,RCR 平均值还可以提供一个准确的指标,用于量化历史上代表性不足的群体的研究生产力,这些群体因发表论文数量等时间依赖性因素而处于不利地位。
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引用次数: 0
Reprint of: Transactional Care and the Looming Glaucoma Public Health Crisis 重印本:事务性护理与迫在眉睫的青光眼公共卫生危机。
IF 2.8 Q1 OPHTHALMOLOGY Pub Date : 2024-11-01 DOI: 10.1016/j.ogla.2024.08.002
Kuldev Singh MD, MPH
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引用次数: 0
Candy-Stripe Hyphema after Laser Peripheral Iridotomy 激光周边虹膜切开术后的糖果状条纹红斑。
IF 2.8 Q1 OPHTHALMOLOGY Pub Date : 2024-11-01 DOI: 10.1016/j.ogla.2024.04.004
Premanand Chandran MS, Rasna Bhanuman DNB, Ganesh V. Raman MS
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引用次数: 0
Outcomes and Baseline Predictors of Failure in Primary Standalone Xen45 Gel Stent versus Trabeculectomy for Glaucoma 初级独立 Xen45 凝胶支架与小梁切除术治疗青光眼失败的结果和基线预测因素。
IF 2.8 Q1 OPHTHALMOLOGY Pub Date : 2024-11-01 DOI: 10.1016/j.ogla.2024.07.002
Jeremy C.K. Tan MD, FRANZCO , Yohei Hashimoto MD, PhD , Pierre Henry Gabrielle PhD , Catherine Creuzot Garcher MD, PhD , Andrew White PhD, FRANZCO , Hamish Dunn MBBS, FRANZCO , Mark Walland FRANZCO, FRACS , David Wechsler MBBS, FRANZCO , Louis Arnould MD, PhD , Mitchell Lawlor PhD, FRANZCO
<div><h3>Purpose</h3><div>To compare safety, effectiveness, and baseline predictors of failure in standalone primary Xen45 gel stent (Xen) versus trabeculectomy (Trab) in glaucoma.</div></div><div><h3>Design</h3><div>Retrospective study.</div></div><div><h3>Subjects</h3><div>Subjects that underwent primary Xen or Trab augmented by mitomycin-C with at least 12 months follow-up.</div></div><div><h3>Methods</h3><div>Multinational observational study of eyes in the Fight Glaucoma Blindness international registry</div></div><div><h3>Main Outcome Measures</h3><div>The primary outcome was success at 12 months defined by intraocular pressure (IOP) reduction ≥ 20% from baseline and ≤ threshold IOPs of 15, 18, and 21 mmHg with (qualified) or without (complete) medications and without secondary glaucoma surgery. Multivariable mixed effects Cox regression models were used to identify risk factors for failure in each cohort.</div></div><div><h3>Results</h3><div>A total of 701 eyes (Xen, 308; Trab, 393) of 596 subjects were included with baseline IOP being significantly higher (22.4 vs. 19.9 mmHg, <em>P</em> < 0.001) and baseline medications significantly lower in the Xen versus the Trab group (2.9 vs. 3.4, <em>P</em> < 0.001). Baseline visual field mean deviation was less severe in the Xen group (–9.47 vs. –13.04 dB, <em>P</em> < 0.001). The proportion of complete surgical success was significantly lower in the Xen versus Trab group across the 3 upper IOP limits at 12 months; 32% versus 52% at 15 mmHg, 37% versus 54% at 18 mmHg, and 39% versus 55% at 21 mmHg (<em>P</em> < 0.001). The incidence of postoperative numerical and symptomatic hypotony was lower in the Xen versus Trab group. In the Xen cohort, a higher failure rate was associated with Asian ethnicity (hazard ratio [HR], 1.97; 95% confidence interval (CI), 1.03–3.79) and use of oral acetazolamide at baseline (HR, 1.74; 95% CI, 1.13–2.70), whereas a lower failure rate was associated with diagnosis of ocular hypertension/open-angle glaucoma suspect (HR, 0.40; 95% CI, 0.20–0.82) and secondary open-angle glaucoma (HR, 0.46; 95% CI, 0.26–0.82). Exposure to prostaglandin analog was associated with greater failure in the Trab group (HR, 2.66; 95% CI, 1.18–6.01).</div></div><div><h3>Conclusions</h3><div>There was significantly greater complete success at 12 months across all complete success definitions for Trab compared with Xen, whereas the rate of postoperative hypotony was significantly lower in the Xen group. Asian ethnicity and use of oral acetazolamide at baseline were associated with greater failure in Xen, whereas exposure to prostaglandin analog was associated with greater failure in Trab patients. Such baseline predictors of success and failure may help guide patient selection for subconjunctival minimally invasive glaucoma surgery in patients undergoing surgical intervention.</div></div><div><h3>Financial Disclosure(s)</h3><div>Proprietary or commercial disclosure may be found in the F
目的:比较独立初级Xen45凝胶支架(Xen)与小梁切除术(Trab)治疗青光眼的安全性、有效性和失败的基线预测因素:设计:回顾性研究:随访至少12个月并接受Xen或Trab术后丝裂霉素-C辅助治疗的受试者:主要结果测量:主要结果是 12 个月时的成功率,定义为眼压较基线降低≥ 20%,且眼压≤ 15mmHg、18mmHg 和 21mmHg 临界值,有(合格)或无(完全)药物治疗,且未进行二次青光眼手术。多变量混合效应考克斯回归模型用于确定每个队列中失败的风险因素:596名受试者中有701只眼睛(Xen组,308只;Trab组,393只)入选,Xen组与Trab组相比,基线眼压明显更高(22.4 mmHg vs 19.9 mmHg,p < 0.001),基线用药明显更少(2.9 mmHg vs 3.4 mmHg,p 结论:Xen组与Trab组相比,基线用药明显更少(2.9 mmHg vs 3.4 mmHg,p < 0.001):在所有完全成功定义中,Trab组在12个月时的完全成功率明显高于Xen组,而Xen组的术后低张力率明显低于Trab组。亚裔和基线使用口服乙酰唑胺与 Xen 的更大失败率相关,而前列腺素类似物与 Trab 患者的更大失败率相关。这些成功和失败的基线预测因素有助于指导接受手术干预的患者选择结膜下微创青光眼手术。
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引用次数: 0
Insight on the Optic Nerve and Ahmed Valve Tube through a Type II Keratoprosthesis 通过 II 型角膜塑形镜观察视神经和艾哈迈德阀管。
IF 2.8 Q1 OPHTHALMOLOGY Pub Date : 2024-11-01 DOI: 10.1016/j.ogla.2024.06.006
Irene Koc BS , Demetrios G. Vavvas MD, PhD , Teresa C. Chen MD
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引用次数: 0
Re: Chan et al.: Effect of preoperative trabecular meshwork pigmentation and other eye characteristics on outcomes of combined phacoemulsification/minimally invasive glaucoma surgery (Ophthalmol Glaucoma. 2024; 7:271-281) Re:Chan等人:术前小梁网色素沉着和其他眼部特征对联合超声乳化/微创青光眼手术疗效的影响》(Ophthalmol Glaucoma.)
IF 2.8 Q1 OPHTHALMOLOGY Pub Date : 2024-11-01 DOI: 10.1016/j.ogla.2024.08.006
Vitor Porto de Souza MD , Fábio Nishimura Kanadani MD, PhD , Augusto Paranhos Jr. MD, PhD , Tiago Santos Prata MD, PhD
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引用次数: 0
Brief Report on 12-Month Outcomes of the ab Interno Gel Stent Using the Intraoperative Posterior Sweep of Tenons (PoST) Technique 使用术中 PoST(腱鞘后扫)技术进行腹腔内凝胶支架 12 个月疗效的简要报告。
IF 2.8 Q1 OPHTHALMOLOGY Pub Date : 2024-11-01 DOI: 10.1016/j.ogla.2024.06.002
Angela Liu BS , Lauren Dhar MD , Sarah Hung BS , Ronald Fellman MD , Davinder S. Grover MD, MPH
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引用次数: 0
Associations between Statin Use and Glaucoma in the All of Us Research Program 我们所有人研究计划中他汀类药物的使用与青光眼之间的关系。
IF 2.8 Q1 OPHTHALMOLOGY Pub Date : 2024-11-01 DOI: 10.1016/j.ogla.2024.07.008
Samuel Y. Lee BA , Megan E. Paul BA , Anne L. Coleman MD, PhD , Ken Kitayama MD, PhD , Fei Yu PhD , Deyu Pan MS , Victoria L. Tseng MD, PhD

Purpose

To investigate associations between statin use and glaucoma in the 2017 to 2022 All of Us (AoU) Research Program.

Design

Cross-sectional, population-based.

Participants

79 742 adult participants aged ≥40 years with hyperlipidemia and with electronic health record (EHR) data in the AoU database.

Methods

Hyperlipidemia, glaucoma status, and statin use were defined by diagnoses and medication information in EHR data collected by AoU. Logistic regression analysis was performed to evaluate the association between statin use and glaucoma likelihood. Logistic regression modeling was used to examine associations between glaucoma and all covariates included in adjusted analysis. Serum low-density lipoprotein cholesterol (LDL-C) was used to assess hyperlipidemia severity. Analyses stratified by LDL-C level and age were performed.

Main Outcome Measures

Any glaucoma as defined by International Classification of Diseases codes found in EHR data.

Results

Of 79 742 individuals with hyperlipidemia in AoU, there were 6365 (8.0%) statin users. Statin use was associated with increased glaucoma prevalence when compared with statin nonuse (adjusted odds ratio [aOR]: 1.13, 95% confidence interval [CI]: 1.01–1.26). Higher serum levels of LDL-C were associated with increased odds of glaucoma (aOR: 1.003, 95% CI: 1.003, 1.004). Statin users had significantly higher LDL-C levels compared to nonusers (144.9 mg/dL versus 136.3 mg/dL, P value < 0.001). Analysis stratified by LDL-C identified positive associations between statin use and prevalence of glaucoma among those with optimal (aOR = 1.39, 95% CI = 1.05–1.82) and high (aOR = 1.37, 95% CI = 1.09–1.70) LDL-C levels. Age-stratified analysis showed a positive association between statin use and prevalence of glaucoma in individuals aged 60 to 69 years (aOR = 1.28, 95% CI = 1.05–1.56).

Conclusions

Statin use was associated with increased glaucoma likelihood in the overall adult AoU population with hyperlipidemia, in individuals with optimal or high LDL-C levels, and in individuals 60 to 69 years old. Findings suggest that statin use may be an independent risk factor for glaucoma, which may furthermore be affected by one’s lipid profile and age.

Financial Disclosures

Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.
目的:在2017-2022年 "我们所有人"(AoU)研究计划中调查他汀类药物的使用与青光眼之间的关联:横断面,基于人群:79,742名年龄≥40岁、患有高脂血症且在AoU数据库中有电子健康记录(EHR)数据的成年参与者。方法:根据AoU收集的EHR数据中的诊断和用药信息来定义高脂血症、青光眼状态和他汀类药物的使用。采用逻辑回归分析评估他汀类药物的使用与青光眼可能性之间的关联。逻辑回归模型用于检查青光眼与调整分析中包含的所有协变量之间的关系。血清低密度脂蛋白胆固醇(LDL-C)用于评估高脂血症的严重程度。根据低密度脂蛋白胆固醇水平和年龄进行分层分析:根据电子病历数据中的国际疾病分类(ICD)代码定义的任何青光眼:在澳大地区的79742名高脂血症患者中,有6365人(8.0%)使用他汀类药物。与不使用他汀类药物相比,使用他汀类药物与青光眼患病率增加有关(调整赔率比 [aOR]:1.13,95% 置信区间 [CI]:1.01-1.26)。血清低密度脂蛋白胆固醇水平越高,患青光眼的几率越大(aOR:1.003,95% CI:1.003,1.004)。他汀类药物使用者的低密度脂蛋白胆固醇水平明显高于非使用者(144.9 mg/dL 对 136.3 mg/dL,P 值 < 0.001)。通过对低密度脂蛋白胆固醇进行分层分析,发现在最佳(aOR = 1.39,95% CI = 1.05-1.82)和高(aOR = 1.37,95% CI = 1.09-1.70)低密度脂蛋白胆固醇水平人群中,他汀类药物的使用与青光眼患病率呈正相关。年龄分层分析显示,他汀类药物的使用与 60-69 岁人群的青光眼患病率呈正相关(aOR = 1.28,95% CI = 1.05-1.56):结论:他汀类药物的使用与患有高脂血症的澳大拉西亚成年人群、低密度脂蛋白胆固醇水平处于最佳或较高水平的人群以及 60-69 岁人群患青光眼的可能性增加有关。研究结果表明,他汀类药物的使用可能是青光眼的一个独立风险因素,而且还可能受到血脂状况和年龄的影响。
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引用次数: 0
Posterior Capsular Pigment Deposition in a Case of Pigmentary Glaucoma 色素性青光眼病例中的后囊色素沉积。
IF 2.8 Q1 OPHTHALMOLOGY Pub Date : 2024-11-01 DOI: 10.1016/j.ogla.2024.04.001
Madhuri Manapakkam MS, DNB, Deepa Ramamoorthy MS, Neethu Mohan MS
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引用次数: 0
期刊
Ophthalmology. Glaucoma
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