首页 > 最新文献

Oper. Res.最新文献

英文 中文
Surgical Case-Mix and Discharge Decisions: Does Within-Hospital Coordination Matter? 外科病例组合和出院决定:院内协调重要吗?
Pub Date : 2021-12-09 DOI: 10.1287/opre.2021.2177
Hessam Bavafa, E. L. Örmeci, Sergei V. Savin, Vanitha Virudachalam
How to Assess the Benefits of Coordination in Managing Hospital Resources In providing patient care, hospitals rely on multiple types of resources, such as operating rooms, recovery beds, labs, and diagnostic equipment, that are often controlled and managed as separate entities and by different decision makers. In “Surgical Case-Mix and Discharge Decisions: Does Within-Hospital Coordination Matter?” Hessam Bavafa, Lerzan Örmeci, Sergei Savin, and Vanitha Virudachalam focus on the interaction between “front-end’’ resources, such as operating rooms, and “backroom’’ resources, such as recovery beds, and compare hospital profitability under the fully coordinated, optimal approach to hospital resource management and under alternative decentralized approaches often encountered in practice. The paper identifies settings in which the benefits of coordination are likely to be high as well as settings in which those benefits are at best moderate. In a given hospital, only hospital managers are in a position to estimate with any degree of certainty potential costs of coordinated management of hospital resources, and the paper’s analysis of the benefits of coordination empowers hospital managers to make informed decisions on the desirability of replacing the often decentralized “status quo” by centralized resource management.
在提供病人护理时,医院依赖于多种类型的资源,如手术室、康复床、实验室和诊断设备,这些资源通常作为独立的实体由不同的决策者控制和管理。在“外科病例组合和出院决定:院内协调重要吗?”Hessam Bavafa、Lerzan Örmeci、Sergei Savin和Vanitha Virudachalam关注“前端”资源(如手术室)和“后台”资源(如康复床位)之间的相互作用,并比较了医院资源管理完全协调的最佳方法和实践中经常遇到的替代分散方法下的医院盈利能力。本文确定了协调的好处可能很高的环境,以及这些好处充其量是中等的环境。在给定的医院中,只有医院管理者能够以某种程度的确定性估计医院资源协调管理的潜在成本,本文对协调效益的分析使医院管理者能够就是否需要用集中的资源管理取代往往分散的“现状”做出明智的决策。
{"title":"Surgical Case-Mix and Discharge Decisions: Does Within-Hospital Coordination Matter?","authors":"Hessam Bavafa, E. L. Örmeci, Sergei V. Savin, Vanitha Virudachalam","doi":"10.1287/opre.2021.2177","DOIUrl":"https://doi.org/10.1287/opre.2021.2177","url":null,"abstract":"How to Assess the Benefits of Coordination in Managing Hospital Resources In providing patient care, hospitals rely on multiple types of resources, such as operating rooms, recovery beds, labs, and diagnostic equipment, that are often controlled and managed as separate entities and by different decision makers. In “Surgical Case-Mix and Discharge Decisions: Does Within-Hospital Coordination Matter?” Hessam Bavafa, Lerzan Örmeci, Sergei Savin, and Vanitha Virudachalam focus on the interaction between “front-end’’ resources, such as operating rooms, and “backroom’’ resources, such as recovery beds, and compare hospital profitability under the fully coordinated, optimal approach to hospital resource management and under alternative decentralized approaches often encountered in practice. The paper identifies settings in which the benefits of coordination are likely to be high as well as settings in which those benefits are at best moderate. In a given hospital, only hospital managers are in a position to estimate with any degree of certainty potential costs of coordinated management of hospital resources, and the paper’s analysis of the benefits of coordination empowers hospital managers to make informed decisions on the desirability of replacing the often decentralized “status quo” by centralized resource management.","PeriodicalId":19546,"journal":{"name":"Oper. Res.","volume":"7 1","pages":"990-1007"},"PeriodicalIF":0.0,"publicationDate":"2021-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81851829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Who Is Next: Patient Prioritization Under Emergency Department Blocking 谁是下一个:急诊科阻塞下的患者优先级
Pub Date : 2021-12-08 DOI: 10.2139/ssrn.3590979
Wenhao Li, Zhankun Sun, L. Hong
In “Who Is Next: Patient Prioritization Under Emergency Department Blocking,” Li, Sun, and Hong study how physicians and nurses choose the next patient for treatment in hospital emergency departments (EDs). Using data from a tertiary hospital in Alberta, Canada, they conduct an empirical investigation and find that both clinical factors and resource constraints are considered in patient-prioritization decisions. In particular, discharged patients are prioritized when ED beds are increasingly occupied by boarding patients so as to avoid further blocking the ED. A stylized model is developed to explain the rationale behind the prioritization behavior. Using a simulation study, they show such behavior can improve ED operations by reducing the average patient waiting time and length of stay without adding extra capacity, which results in significant cost savings for hospitals.
在“谁是下一个:急诊科阻塞下的病人优先排序”一文中,李、孙和洪研究了医生和护士如何选择医院急诊科的下一个病人进行治疗。利用来自加拿大阿尔伯塔省一家三级医院的数据,他们进行了一项实证调查,发现临床因素和资源限制都被考虑在患者优先级决策中。特别是,当急诊科床位越来越多地被寄宿病人占用时,出院病人被优先考虑,以避免进一步阻塞急诊科。开发了一个程式化模型来解释优先考虑行为背后的基本原理。通过模拟研究,他们发现这种行为可以在不增加额外容量的情况下,通过减少病人的平均等待时间和住院时间来改善急诊科手术,从而为医院节省大量成本。
{"title":"Who Is Next: Patient Prioritization Under Emergency Department Blocking","authors":"Wenhao Li, Zhankun Sun, L. Hong","doi":"10.2139/ssrn.3590979","DOIUrl":"https://doi.org/10.2139/ssrn.3590979","url":null,"abstract":"In “Who Is Next: Patient Prioritization Under Emergency Department Blocking,” Li, Sun, and Hong study how physicians and nurses choose the next patient for treatment in hospital emergency departments (EDs). Using data from a tertiary hospital in Alberta, Canada, they conduct an empirical investigation and find that both clinical factors and resource constraints are considered in patient-prioritization decisions. In particular, discharged patients are prioritized when ED beds are increasingly occupied by boarding patients so as to avoid further blocking the ED. A stylized model is developed to explain the rationale behind the prioritization behavior. Using a simulation study, they show such behavior can improve ED operations by reducing the average patient waiting time and length of stay without adding extra capacity, which results in significant cost savings for hospitals.","PeriodicalId":19546,"journal":{"name":"Oper. Res.","volume":"46 1","pages":"821-842"},"PeriodicalIF":0.0,"publicationDate":"2021-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75032851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
Constrained Assortment Optimization Under the Paired Combinatorial Logit Model 配对组合Logit模型下的约束分类优化
Pub Date : 2021-12-07 DOI: 10.1287/opre.2021.2188
R. Ghuge, J. Kwon, V. Nagarajan, Adetee Sharma
Assortment optimization involves selecting a subset of products to offer to customers in order to maximize revenue. Often, the selected subset must also satisfy some constraints, such as capacity or space usage. Two key aspects in assortment optimization are (1) modeling customer behavior and (2) computing optimal or near-optimal assortments efficiently. The paired combinatorial logit (PCL) model is a generic customer choice model that allows for arbitrary correlations in the utilities of different products. The PCL model has greater modeling power than other choice models, such as multinomial-logit and nested-logit. In “Constrained Assortment Optimization Under the Paired Combinatorial Logit Model,” Ghuge, Kwon, Nagarajan, and and Sharma provide efficient algorithms that find provably near-optimal solutions for PCL assortment optimization under several types of constraints. These include the basic unconstrained problem (which is already intractable to solve exactly), multidimensional space constraints, and partition constraints. The authors also demonstrate via extensive experiments that their algorithms typically achieve over 95% of the optimal revenues.
分类优化包括选择产品的子集提供给客户,以最大限度地提高收入。通常,选择的子集还必须满足一些约束,例如容量或空间使用。分类优化的两个关键方面是:(1)客户行为建模和(2)有效地计算最优或接近最优分类。配对组合logit (PCL)模型是一种通用的客户选择模型,它允许在不同产品的实用程序中进行任意关联。PCL模型比其他选择模型(如多项logit和嵌套logit)具有更强的建模能力。在“配对组合Logit模型下的约束分类优化”中,Ghuge, Kwon, Nagarajan和Sharma提供了有效的算法,可以在几种类型的约束下找到可证明的PCL分类优化的近最优解。这些问题包括基本的无约束问题(已经难以精确解决)、多维空间约束和分区约束。作者还通过大量的实验证明,他们的算法通常能达到95%以上的最优收益。
{"title":"Constrained Assortment Optimization Under the Paired Combinatorial Logit Model","authors":"R. Ghuge, J. Kwon, V. Nagarajan, Adetee Sharma","doi":"10.1287/opre.2021.2188","DOIUrl":"https://doi.org/10.1287/opre.2021.2188","url":null,"abstract":"Assortment optimization involves selecting a subset of products to offer to customers in order to maximize revenue. Often, the selected subset must also satisfy some constraints, such as capacity or space usage. Two key aspects in assortment optimization are (1) modeling customer behavior and (2) computing optimal or near-optimal assortments efficiently. The paired combinatorial logit (PCL) model is a generic customer choice model that allows for arbitrary correlations in the utilities of different products. The PCL model has greater modeling power than other choice models, such as multinomial-logit and nested-logit. In “Constrained Assortment Optimization Under the Paired Combinatorial Logit Model,” Ghuge, Kwon, Nagarajan, and and Sharma provide efficient algorithms that find provably near-optimal solutions for PCL assortment optimization under several types of constraints. These include the basic unconstrained problem (which is already intractable to solve exactly), multidimensional space constraints, and partition constraints. The authors also demonstrate via extensive experiments that their algorithms typically achieve over 95% of the optimal revenues.","PeriodicalId":19546,"journal":{"name":"Oper. Res.","volume":"63 1","pages":"786-804"},"PeriodicalIF":0.0,"publicationDate":"2021-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84047899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Data-Driven Robust Resource Allocation with Monotonic Cost Functions 具有单调成本函数的数据驱动鲁棒资源分配
Pub Date : 2021-12-01 DOI: 10.1287/opre.2021.2145
Ye Chen, Nikola Marković, I. Ryzhov, P. Schonfeld
Using Data to Allocate Resources Efficiently In city logistics systems, a fleet of vehicles is divided between service regions that function autonomously. Each region finds optimal routes for its own fleet and incurs costs accordingly. More vehicles lead to lower costs, but the trade-off is that fewer vehicles are left for other regions. Costs are difficult to quantify precisely because of demand uncertainty but can be estimated using data. The paper “Data-driven robust resource allocation with monotonic cost functions” by Chen, Marković, Ryzhov, and Schonfeld develops a principled risk-averse approach for two-stage resource allocation. The authors propose a new uncertainty model for decreasing cost functions and show how it can be leveraged to efficiently find resource allocations that demonstrably reduce the frequency of high-cost scenarios. This framework combines statistics and optimization in a novel way and is applicable to a general class of resource allocation problems, encompassing facility location, vehicle routing, and discrete-event simulation.
在城市物流系统中,车队被划分为自主运作的服务区域。每个地区为自己的车队找到最优路线,并相应地产生成本。更多的车辆带来更低的成本,但代价是留给其他地区的车辆减少了。由于需求的不确定性,成本难以精确量化,但可以利用数据进行估算。Chen、markovovic、Ryzhov和Schonfeld的论文“单调成本函数下的数据驱动鲁棒资源配置”开发了一种原则性的风险规避方法用于两阶段资源配置。作者提出了一个新的降低成本函数的不确定性模型,并展示了如何利用它来有效地找到明显减少高成本情景频率的资源分配。该框架以一种新颖的方式结合了统计和优化,适用于一般类型的资源分配问题,包括设施定位、车辆路线和离散事件模拟。
{"title":"Data-Driven Robust Resource Allocation with Monotonic Cost Functions","authors":"Ye Chen, Nikola Marković, I. Ryzhov, P. Schonfeld","doi":"10.1287/opre.2021.2145","DOIUrl":"https://doi.org/10.1287/opre.2021.2145","url":null,"abstract":"Using Data to Allocate Resources Efficiently In city logistics systems, a fleet of vehicles is divided between service regions that function autonomously. Each region finds optimal routes for its own fleet and incurs costs accordingly. More vehicles lead to lower costs, but the trade-off is that fewer vehicles are left for other regions. Costs are difficult to quantify precisely because of demand uncertainty but can be estimated using data. The paper “Data-driven robust resource allocation with monotonic cost functions” by Chen, Marković, Ryzhov, and Schonfeld develops a principled risk-averse approach for two-stage resource allocation. The authors propose a new uncertainty model for decreasing cost functions and show how it can be leveraged to efficiently find resource allocations that demonstrably reduce the frequency of high-cost scenarios. This framework combines statistics and optimization in a novel way and is applicable to a general class of resource allocation problems, encompassing facility location, vehicle routing, and discrete-event simulation.","PeriodicalId":19546,"journal":{"name":"Oper. Res.","volume":"19 1","pages":"73-94"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88598811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Computing Constrained Shortest-Paths at Scale 大规模计算约束最短路径
Pub Date : 2021-11-30 DOI: 10.1287/opre.2021.2166
Alberto Vera, Siddhartha Banerjee, S. Samaranayake
Motivated by the needs of modern transportation service platforms, we study the problem of computing constrained shortest paths (CSP) at scale via preprocessing techniques. Our work makes two contributions in this regard: 1) We propose a scalable algorithm for CSP queries and show how its performance can be parametrized in terms of a new network primitive, the constrained highway dimension. This development extends recent work that established the highway dimension as the appropriate primitive for characterizing the performance of unconstrained shortest-path (SP) algorithms. Our main theoretical contribution is deriving conditions relating the two notions, thereby providing a characterization of networks where CSP and SP queries are of comparable hardness. 2) We develop practical algorithms for scalable CSP computation, augmenting our theory with additional network clustering heuristics. We evaluate these algorithms on real-world data sets to validate our theoretical findings. Our techniques are orders of magnitude faster than existing approaches while requiring only limited additional storage and preprocessing.
受现代交通服务平台需求的驱动,我们通过预处理技术研究了大规模计算约束最短路径(CSP)的问题。我们的工作在这方面做出了两个贡献:1)我们提出了一种可扩展的CSP查询算法,并展示了如何根据一个新的网络原语(约束高速公路维度)来参数化其性能。这一发展扩展了最近的工作,该工作将高速公路维度作为描述无约束最短路径(SP)算法性能的适当原语。我们的主要理论贡献是推导了两个概念相关的条件,从而提供了CSP和SP查询具有可比硬度的网络的特征。2)我们开发了可扩展CSP计算的实用算法,用额外的网络聚类启发式来增强我们的理论。我们在真实世界的数据集上评估这些算法,以验证我们的理论发现。我们的技术比现有的方法快几个数量级,同时只需要有限的额外存储和预处理。
{"title":"Computing Constrained Shortest-Paths at Scale","authors":"Alberto Vera, Siddhartha Banerjee, S. Samaranayake","doi":"10.1287/opre.2021.2166","DOIUrl":"https://doi.org/10.1287/opre.2021.2166","url":null,"abstract":"Motivated by the needs of modern transportation service platforms, we study the problem of computing constrained shortest paths (CSP) at scale via preprocessing techniques. Our work makes two contributions in this regard: 1) We propose a scalable algorithm for CSP queries and show how its performance can be parametrized in terms of a new network primitive, the constrained highway dimension. This development extends recent work that established the highway dimension as the appropriate primitive for characterizing the performance of unconstrained shortest-path (SP) algorithms. Our main theoretical contribution is deriving conditions relating the two notions, thereby providing a characterization of networks where CSP and SP queries are of comparable hardness. 2) We develop practical algorithms for scalable CSP computation, augmenting our theory with additional network clustering heuristics. We evaluate these algorithms on real-world data sets to validate our theoretical findings. Our techniques are orders of magnitude faster than existing approaches while requiring only limited additional storage and preprocessing.","PeriodicalId":19546,"journal":{"name":"Oper. Res.","volume":"16 11 1","pages":"160-178"},"PeriodicalIF":0.0,"publicationDate":"2021-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91066583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Technical Note - A Permutation-Dependent Separability Approach for Capacitated Two-Echelon Inventory Systems 技术说明-有能力的两梯队库存系统的一种依赖于置换的可分离性方法
Pub Date : 2021-11-19 DOI: 10.1287/opre.2021.2194
Xiaobei Shen, Yimin Yu, W. T. Huh
Analyzing Capacitated Two-Echelon Systems with Permutation-Dependent Separability Capacitated multiechelon systems are common in practice due to the escalating costs of labor and advanced manufacturing technology. However, identifying the optimal replenishment policies for such systems is a largely open area of research due to the intrinsic complexity, especially when there is an upstream bottleneck. In “A Permutation-Dependent Separability Approach for Capacitated Two-Echelon Inventory Systems”, Shen, Yu, and Huh propose a new approach, that is, permutation-dependent separability, to tackle a capacitated two-echelon system in which the capacity of upstream stage can be the bottleneck. They show that the value function for the capacitated two-echelon system in each period is permutation-dependent separable, and that for each echelon, a permutation-dependent echelon base stock policy is optimal. The authors also develop efficient solution procedures on how to obtain the optimal policy.
由于人工成本的不断上升和先进制造技术的不断发展,可容多级系统在实际应用中越来越普遍。然而,由于固有的复杂性,特别是当存在上游瓶颈时,确定这种系统的最佳补充政策在很大程度上是一个开放的研究领域。Shen, Yu, and Huh在“A置换依赖可分性方法for Capacitated Two-Echelon Inventory system”中,针对上游阶段的产能可能成为瓶颈的有能力两梯队系统,提出了一种新的方法,即置换依赖可分性。结果表明,有能力的两梯队系统在每个时期的价值函数是置换依赖的可分离的,并且对于每个梯队,置换依赖的梯队基存量策略是最优的。作者还开发了如何获得最优策略的有效求解程序。
{"title":"Technical Note - A Permutation-Dependent Separability Approach for Capacitated Two-Echelon Inventory Systems","authors":"Xiaobei Shen, Yimin Yu, W. T. Huh","doi":"10.1287/opre.2021.2194","DOIUrl":"https://doi.org/10.1287/opre.2021.2194","url":null,"abstract":"Analyzing Capacitated Two-Echelon Systems with Permutation-Dependent Separability Capacitated multiechelon systems are common in practice due to the escalating costs of labor and advanced manufacturing technology. However, identifying the optimal replenishment policies for such systems is a largely open area of research due to the intrinsic complexity, especially when there is an upstream bottleneck. In “A Permutation-Dependent Separability Approach for Capacitated Two-Echelon Inventory Systems”, Shen, Yu, and Huh propose a new approach, that is, permutation-dependent separability, to tackle a capacitated two-echelon system in which the capacity of upstream stage can be the bottleneck. They show that the value function for the capacitated two-echelon system in each period is permutation-dependent separable, and that for each echelon, a permutation-dependent echelon base stock policy is optimal. The authors also develop efficient solution procedures on how to obtain the optimal policy.","PeriodicalId":19546,"journal":{"name":"Oper. Res.","volume":"56 1","pages":"1953-1968"},"PeriodicalIF":0.0,"publicationDate":"2021-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83955739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adversarial Patrolling in a Uniform 穿着制服进行敌对巡逻
Pub Date : 2021-11-18 DOI: 10.1287/opre.2021.2152
S. Alpern, P. Chleboun, S. Katsikas, Kyle Y. Lin
Many of us will have seen uniformed guards patrolling in museums, airports, and other places where thefts or attacks are possible. In other similar places, we may have been unaware of undercover agents carrying out similar patrols. The latter type of patrollers has been modeled in recent literature. However, when the patroller is visible (wears a uniform), the potential thief or terrorist may be able to spot him when he is nearby and to time his theft appropriately. For example, the thief may wait a specified time after the uniformed patroller leaves his area. In “The Uniformed Patroller Game,” Steve Alpern, Paul Chleboun, Stamatios Katsikas, and Kyle Y. Lin study the effect on the patrolling game of having a visible (uniformed) patroller. It turns out that putting a uniform on the patroller greatly reduces his effectiveness in intercepting thefts or attacks. Of course, the visibility of a uniform may act as a deterrent to having the theft take place at all.
我们中的许多人会看到穿制服的警卫在博物馆、机场和其他可能发生盗窃或袭击的地方巡逻。在其他类似的地方,我们可能不知道卧底特工也在进行类似的巡逻。后一种类型的巡逻员已在最近的文献中建模。然而,当巡警出现时(穿着制服),当他在附近时,潜在的小偷或恐怖分子可能会发现他,并适当地选择盗窃时间。例如,小偷可能在穿制服的巡警离开他的区域后等待一段指定的时间。在“穿制服的巡逻游戏”中,Steve Alpern, Paul Chleboun, Stamatios Katsikas和Kyle Y. Lin研究了有一个可见的(穿制服的)巡逻对巡逻游戏的影响。事实证明,给巡警穿上制服大大降低了他拦截盗窃或袭击的效率。当然,制服的可见性可能会起到阻止盗窃发生的作用。
{"title":"Adversarial Patrolling in a Uniform","authors":"S. Alpern, P. Chleboun, S. Katsikas, Kyle Y. Lin","doi":"10.1287/opre.2021.2152","DOIUrl":"https://doi.org/10.1287/opre.2021.2152","url":null,"abstract":"Many of us will have seen uniformed guards patrolling in museums, airports, and other places where thefts or attacks are possible. In other similar places, we may have been unaware of undercover agents carrying out similar patrols. The latter type of patrollers has been modeled in recent literature. However, when the patroller is visible (wears a uniform), the potential thief or terrorist may be able to spot him when he is nearby and to time his theft appropriately. For example, the thief may wait a specified time after the uniformed patroller leaves his area. In “The Uniformed Patroller Game,” Steve Alpern, Paul Chleboun, Stamatios Katsikas, and Kyle Y. Lin study the effect on the patrolling game of having a visible (uniformed) patroller. It turns out that putting a uniform on the patroller greatly reduces his effectiveness in intercepting thefts or attacks. Of course, the visibility of a uniform may act as a deterrent to having the theft take place at all.","PeriodicalId":19546,"journal":{"name":"Oper. Res.","volume":"36 1","pages":"129-140"},"PeriodicalIF":0.0,"publicationDate":"2021-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81916406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Optimal Genetic Screening for Cystic Fibrosis 囊性纤维化的最佳基因筛选
Pub Date : 2021-11-16 DOI: 10.1287/opre.2021.2134
Hussein El Hajj, D. R. Bish, E. Bish
Improving Newborn Screening for Genetic Diseases Screening newborns for life-threatening genetic diseases is an important public health initiative. Cystic fibrosis is one of the most prevalent diseases in this context. As part of the cystic fibrosis screening process, all states in the United States use multiple tests, including genetic tests that detect a subset of the more than 300 genetic variants (specific mutations) that cause cystic fibrosis. In “Optimal Genetic Screening for Cystic Fibrosis,” El-Hajj, D.R. Bish, and E.K. Bish develop a decision support model to select which genetic variants to screen for, considering the trade-off between classification accuracy and testing cost, and the technological constraints that limit the number of variants selected. Because variant prevalence rates are highly uncertain, a robust optimization framework is developed. Further, two commonly used cystic fibrosis screening processes are analytically compared, and conditions under which each process dominates are established. A case study based on published data are provided.
对新生儿进行威胁生命的遗传病筛查是一项重要的公共卫生举措。囊性纤维化是这方面最普遍的疾病之一。作为囊性纤维化筛查过程的一部分,美国所有州都使用多种检测,包括检测导致囊性纤维化的300多种遗传变异(特定突变)中的一个子集的基因检测。El-Hajj、dr . Bish和E.K. Bish在“囊性纤维化的最佳基因筛查”一篇文章中,考虑到分类准确性和检测成本之间的权衡,以及限制所选变异数量的技术限制,开发了一个决策支持模型来选择筛选哪些遗传变异。由于变异患病率具有高度的不确定性,因此开发了一个鲁棒优化框架。进一步,分析比较了两种常用的囊性纤维化筛查方法,并确定了每种方法占主导地位的条件。提供了一个基于已发表数据的案例研究。
{"title":"Optimal Genetic Screening for Cystic Fibrosis","authors":"Hussein El Hajj, D. R. Bish, E. Bish","doi":"10.1287/opre.2021.2134","DOIUrl":"https://doi.org/10.1287/opre.2021.2134","url":null,"abstract":"Improving Newborn Screening for Genetic Diseases Screening newborns for life-threatening genetic diseases is an important public health initiative. Cystic fibrosis is one of the most prevalent diseases in this context. As part of the cystic fibrosis screening process, all states in the United States use multiple tests, including genetic tests that detect a subset of the more than 300 genetic variants (specific mutations) that cause cystic fibrosis. In “Optimal Genetic Screening for Cystic Fibrosis,” El-Hajj, D.R. Bish, and E.K. Bish develop a decision support model to select which genetic variants to screen for, considering the trade-off between classification accuracy and testing cost, and the technological constraints that limit the number of variants selected. Because variant prevalence rates are highly uncertain, a robust optimization framework is developed. Further, two commonly used cystic fibrosis screening processes are analytically compared, and conditions under which each process dominates are established. A case study based on published data are provided.","PeriodicalId":19546,"journal":{"name":"Oper. Res.","volume":"1 1","pages":"265-287"},"PeriodicalIF":0.0,"publicationDate":"2021-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89835452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Optimal Market-Integration Decisions by Policymakers: Modeling and Analysis of Agriculture Market Data 决策者的最优市场整合决策:农业市场数据的建模与分析
Pub Date : 2021-11-16 DOI: 10.1287/opre.2021.2191
Shivam Gupta, S. Bansal
Policymakers often seek to integrate markets as a way to maximize social welfare. In this article, the authors consider the spectrum of all possible integration policies, from full isolation to complete integration, and characterize the socially optimal market integration, under general demands. They identify market conditions under which social surplus is indeed maximized at partial market integration. For the linear price-responsive demand model that is used extensively in the operations management literature, these conditions are identified as thresholds on (i) the relative size of the markets being integrated, and (ii) the relative price sensitivity of consumers in these markets. The authors then apply the model to the commercial seed market in the European Union (EU). Their analysis shows that socially optimal market integration for these countries provides a further improvement in the social surplus for the EU by 2.80%, relative to complete integration. Results show that policymakers should exercise caution in determining the extent to which markets are integrated.
政策制定者经常寻求整合市场,作为实现社会福利最大化的一种方式。在本文中,作者考虑了所有可能的整合政策的范围,从完全隔离到完全整合,并描述了一般需求下的社会最优市场整合。它们确定了在部分市场一体化时社会剩余确实最大化的市场条件。对于在运营管理文献中广泛使用的线性价格响应需求模型,这些条件被确定为(i)正在整合的市场的相对规模和(ii)这些市场中消费者的相对价格敏感性的阈值。然后,作者将该模型应用于欧盟的商业种子市场。他们的分析表明,相对于完全一体化,这些国家的社会最优市场一体化为欧盟提供了2.80%的社会剩余进一步改善。结果表明,政策制定者在确定市场一体化程度时应谨慎行事。
{"title":"Optimal Market-Integration Decisions by Policymakers: Modeling and Analysis of Agriculture Market Data","authors":"Shivam Gupta, S. Bansal","doi":"10.1287/opre.2021.2191","DOIUrl":"https://doi.org/10.1287/opre.2021.2191","url":null,"abstract":"Policymakers often seek to integrate markets as a way to maximize social welfare. In this article, the authors consider the spectrum of all possible integration policies, from full isolation to complete integration, and characterize the socially optimal market integration, under general demands. They identify market conditions under which social surplus is indeed maximized at partial market integration. For the linear price-responsive demand model that is used extensively in the operations management literature, these conditions are identified as thresholds on (i) the relative size of the markets being integrated, and (ii) the relative price sensitivity of consumers in these markets. The authors then apply the model to the commercial seed market in the European Union (EU). Their analysis shows that socially optimal market integration for these countries provides a further improvement in the social surplus for the EU by 2.80%, relative to complete integration. Results show that policymakers should exercise caution in determining the extent to which markets are integrated.","PeriodicalId":19546,"journal":{"name":"Oper. Res.","volume":"16 1","pages":"352-362"},"PeriodicalIF":0.0,"publicationDate":"2021-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91283686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
A Fluid-Diffusion-Hybrid Limiting Approximation for Priority Systems with Fast and Slow Customers 具有快客户和慢客户的优先级系统的流体-扩散-混合极限逼近
Pub Date : 2021-11-15 DOI: 10.1287/opre.2021.2154
Lun Yu, S. Iravani, Ohad Perry
The paper “Fluid-Diffusion-Hybrid (FDH) Approximation” proposes a new heavy-traffic asymptotic regime for a two-class priority system in which the high-priority customers require substantially larger service times than the low-priority customers. In the FDH limit, the high-priority queue is a diffusion, whereas the low-priority queue operates as a (random) fluid limit, whose dynamics are driven by the former diffusion. A characterizing property of our limit process is that, unlike other asymptotic regimes, a non-negligible proportion of the customers from both classes must wait for service. This property allows us to study the costs and benefits of de-pooling, and prove that a two-pool system is often the asymptotically optimal design of the system.
本文针对一类高优先级用户比低优先级用户需要更大服务时间的两类优先级系统,提出了一种新的大流量渐近算法。在FDH极限中,高优先级队列是一种扩散,而低优先级队列是一种(随机)流体极限,其动力学是由前者的扩散驱动的。我们的极限过程的一个特征性质是,与其他渐近区域不同,两个类别的客户中都有不可忽略的比例必须等待服务。这一性质使我们能够研究去池化的成本和收益,并证明双池系统通常是系统的渐近最优设计。
{"title":"A Fluid-Diffusion-Hybrid Limiting Approximation for Priority Systems with Fast and Slow Customers","authors":"Lun Yu, S. Iravani, Ohad Perry","doi":"10.1287/opre.2021.2154","DOIUrl":"https://doi.org/10.1287/opre.2021.2154","url":null,"abstract":"The paper “Fluid-Diffusion-Hybrid (FDH) Approximation” proposes a new heavy-traffic asymptotic regime for a two-class priority system in which the high-priority customers require substantially larger service times than the low-priority customers. In the FDH limit, the high-priority queue is a diffusion, whereas the low-priority queue operates as a (random) fluid limit, whose dynamics are driven by the former diffusion. A characterizing property of our limit process is that, unlike other asymptotic regimes, a non-negligible proportion of the customers from both classes must wait for service. This property allows us to study the costs and benefits of de-pooling, and prove that a two-pool system is often the asymptotically optimal design of the system.","PeriodicalId":19546,"journal":{"name":"Oper. Res.","volume":"2 1","pages":"2579-2596"},"PeriodicalIF":0.0,"publicationDate":"2021-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90550899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
期刊
Oper. Res.
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1