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Diagnosis by Raman Spectroscopy of Pre-Malignant and Malignant Oral Lesions: A Systematic Review 用拉曼光谱诊断口腔癌前病变和恶性病变:系统综述
Pub Date : 2019-01-01 DOI: 10.35248/2247-2452.19.18.1081
Rodrigues Rea, Timbó Mf, Rifane To, Rocha Dd, Vieira Aps, Feitosa Vp
Raman spectroscopy is a technique that uses a monochromatic source of light-generating light of the same and different incident energy, thus allowing to obtain the frequency of atoms and molecules vibration to detect chemical connection or geometry, which allows discovering the chemical composition. This technique has great relevance for the early diagnosis of premalignant and malignant lesions due to its practicality and lack of invasiveness. The aim of this study was to evaluate the success of Raman spectroscopy on early diagnosis of oral lesions with a predisposition to malignancy and malignant lesions. A literature review was carried out in PubMed, SciELO, Google Scholar and Lilacs databases, using keywords "precancerous lesions", "Raman Spectral Analysis" and "oral neoplasia". Thirty-two articles were found and 12 were selected, based on the exclusion criteria (review articles and articles that were not studying oral lesions). The high success rates of Raman spectroscopic technique was observed in the rapid identification of malignant or premalignant cells other forms of oral dysplasias in oral lesions due to the practicality of the laser apparatus and lack of invasiveness. It is concluded that the diagnosis by Raman spectroscopy is effective due to its ease-of-use and a great possibility to provide early diagnosis affording successful treatment of oral precancer and cancer.
拉曼光谱是一种使用单色光源产生相同和不同入射能量的光的技术,从而可以获得原子和分子振动的频率,以检测化学连接或几何形状,从而可以发现化学成分。该技术实用性强,无侵入性,对恶性病变的早期诊断具有重要意义。本研究的目的是评估拉曼光谱在早期诊断有恶性和恶性病变倾向的口腔病变的成功。检索PubMed、SciELO、Google Scholar和Lilacs数据库,检索关键词为“癌前病变”、“拉曼光谱分析”和“口腔肿瘤”。根据排除标准(综述性文章和非研究口腔病变的文章),共发现32篇文章,选择12篇。由于激光设备的实用性和缺乏侵入性,拉曼光谱技术在快速识别口腔病变中的恶性或癌前细胞和其他形式的口腔发育不良方面具有很高的成功率。结论:拉曼光谱诊断是有效的,因为它易于使用,提供早期诊断和成功治疗口腔癌前和癌的可能性很大。
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引用次数: 1
Changes in Oral Microflora Related to Immunosuppressive Chemotherapy in Denture Wearing Cancer Patients 戴假牙肿瘤患者免疫抑制化疗相关口腔菌群变化
Pub Date : 2019-01-01 DOI: 10.35248/2247-2452.19.18.1083
Waseem B Mushtah
Objective: To investigate changes in oral microflora in oral cavity from denture wearing cancer patients within seven days of the first course of chemotherapy, and the association between these changes and the distressing oral problems of the patients. Material and methods: Prospective uncontrolled study design was carried out with sixty cancer patients were enrolled in this study. Oral microflora of the buccal mucosa was cultured from two saliva samples before chemotherapy and after receiving the first dose of chemotherapy. Convenience-based sampling method was used based on the patient availability on recruitment days. Informed consent was obtained from the patients for enrollment in the present study. Results: The results from this study have shown that in general, no statistically significant differences were found in the existence of bacteria between before and after chemotherapy, there is no association between the changes of bacterial types and chemotherapy. Types and number of oral bacteria were found to correlate to degree of oral health care or oral hygiene, saliva, and gender, and there is a direct relation between chemotherapy and decrease saliva amount and viscosity and the development of bad oral habits after chemotherapy in these patients. Conclusion: the results of this study indicate that there were no changes in the microflora in the oral cavity in denture wearing cancer patients within seven days of the first dose of chemotherapy. No correlations between oral mucositis and specific microorganisms were assessed.
目的:探讨假牙患者首次化疗后7天内口腔菌群的变化及其与患者口腔疾患的关系。材料与方法:采用前瞻性非对照研究设计,纳入60例癌症患者。在化疗前和第一次化疗后分别对两组唾液样本进行口腔黏膜菌群培养。根据招募日患者的可用性,采用方便抽样方法。本研究的入组均获得患者的知情同意。结果:本研究结果显示,总体而言,化疗前后细菌的存在无统计学差异,细菌类型的变化与化疗之间无相关性。口腔细菌的种类和数量与口腔保健或口腔卫生程度、唾液、性别相关,化疗与患者化疗后唾液量和黏度下降及不良口腔习惯的形成有直接关系。结论:本研究结果表明,假牙佩戴的癌症患者在第一次化疗后7天内口腔内的微生物群没有发生变化。口腔黏膜炎与特定微生物之间没有相关性。
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引用次数: 0
Investigation of Anterior Tooth Dimensions and Color Distribution of Young Patients of Turkish Society 土耳其社会青年患者前牙尺寸及颜色分布的调查
Pub Date : 2019-01-01 DOI: 10.35248/2247-2452.19.18.1082
Merve Köseoğlu, Nuran Yanıkoğlu
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引用次数: 0
Literature Review on Adaptation of Fixed Prosthesis Metal Infrastructure 固定假体金属基础设施适应性的文献综述
Pub Date : 2019-01-01 DOI: 10.35248/2247-2452.19.18.1075
É. Paraguassu, Ulisses Gomes Guimarães Neto, Alan Mesquita Santos, Carolina Pantoja Cal, rine de Azevedo, André Fabricio da Costa Oliveir, Karina da SilvaFigueira.
This article aims to carry out a systematic review of the current medical literature on the adaptation of structures of prostheses on prefabricated implants or melted in titanium, before and after laser welding. It was used as methodology a scan was carried out on the main indexing platforms for scientific articles. We found 40 articles on the subject; however, 24 had a low impact factor or index on the Qualis platform below B2 and were discharged. According to the method employed and based on the results obtained in the literature for the two techniques studied, it was concluded that the monoblock technique is safer than the distal bar technique since this technique promotes less or no distortion which would promote stresses on the implants.
本文旨在对目前医学文献中关于激光焊接前后假体与预制植入物或钛熔体的结构适应性进行系统综述。它被用作方法学,在主要的科学文章索引平台上进行扫描。我们找到了40篇关于这个主题的文章;然而,有24个在Qualis平台上的影响因子或指数低于B2,并被释放。根据所采用的方法和文献中对这两种技术的研究结果,我们得出结论,单块技术比远端杆技术更安全,因为该技术导致的变形更小或没有变形,而变形会增加种植体的应力。
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引用次数: 3
Dentin Biomodification Agents in Dentistry–A Critical Review 牙本质生物修饰剂在牙科中的应用综述
Pub Date : 2019-01-01 DOI: 10.35248/2247-2452.19.18.1076
Bárbara de Fátima Barboza de Freitas, Antônio Moisés Parente da Ponte, Fabrício Rômulo Sampaio Farias, Victor Pinheiro Feitosa, Diego Martins de Paula
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引用次数: 0
Albanian Dentist’s Attitude towards Pain-Free Local Anesthetics in Children, A Country Profile 阿尔巴尼亚牙医对儿童无痛局麻药的态度:一个国家概况
Pub Date : 2019-01-01 DOI: 10.35248/2247-2452.19.18.1067
D. Hysi, E. Çaglar, E. Droboniku, Ç. Toti, Enida Petro, O. Kuscu
Aim: The aim of this study was to access the Albanian dentist’s attitude and perception toward pain-free dental injections in children. Methods: The survey was conducted in Tirana, Albania. A questionnaire regarding the dentist’s attitude toward “Pain-free Local Anesthetic Techniques in Children” was used. It was structured as anonymous with six closed-ended questions in a Liker scale. Also, dentist information about gender, age, region and years of practice was part of the form. The information collected was analyzed using IBM SPSS 20. Descriptive statistics and one way ANOVA was used in comparing groups. The results were evaluated within a 95% confidence interval. Statistical significance level was established at p<0.05. Results: A total of 203 dentists were included in the study. 86 (42.4%) were male and 117 (57.6%) were female dentists. Their mean age was 35 years old (sd 10.1) and the mean clinical practice experience was 10 years old (sd 9.5). 72 (35.5%) of dentists believed that pain is inevitable during local anesthesia in children and 158 (77.8%) agreed that cotton pallet should be better applied as a topical anesthetics. 128 (63%) of dentists believed in the possibility of pain-free local anesthesia in children. There was a higher agreement in males but not statistically significant. There was a statistically significant higher agreement between dentists in Tirana (the capital) p<0.03 compared with the other regions while experience (p<0.2) and age (p<0.9) did not show any significant change Conclusions: A higher proportion of Albanian dentists believe the importance of pain free dental injections in children. Especially dentists in urban seem to perform pain-free LA injections.
目的:本研究的目的是了解阿尔巴尼亚牙医对儿童无痛牙科注射的态度和看法。方法:在阿尔巴尼亚地拉那进行调查。采用一份关于牙医对“儿童无痛局麻技术”态度的调查问卷。它的结构是匿名的,在李克氏量表中有六个封闭式问题。此外,牙医的性别、年龄、地区和执业年限等信息也是表格的一部分。使用IBM SPSS 20对收集到的信息进行分析。组间比较采用描述性统计和单因素方差分析。结果在95%置信区间内进行评估。差异有统计学意义,p<0.05。结果:本研究共纳入203名牙医。86名(42.4%)为男性牙医,117名(57.6%)为女性牙医。他们的平均年龄为35岁(sd 10.1),平均临床经验为10岁(sd 9.5)。72名(35.5%)牙医认为儿童局部麻醉时疼痛是不可避免的,158名(77.8%)牙医认为应更好地使用棉托作为局部麻醉剂。128位(63%)牙医相信儿童无痛局部麻醉的可能性。在男性中有更高的一致性,但没有统计学意义。地拉那(首都)牙医与其他地区相比(p< 0.03)一致性较高,经验(p<0.2)和年龄(p<0.9)差异无统计学意义。结论:阿尔巴尼亚牙医认为儿童无痛牙科注射的重要性比例较高。尤其是城市里的牙医似乎会进行无痛的洛杉矶注射。
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引用次数: 0
A Rare Case of Traumatic Ulcerative Granuloma with Stromal Eosinophilia of the Tongue (Tugse) in a Child: Diagnostic Problems and Differential Diagnosis 一例罕见的儿童创伤性溃疡性肉芽肿伴舌间质嗜酸性粒细胞增多:诊断问题与鉴别诊断
Pub Date : 2019-01-01 DOI: 10.35248/2247-2452.19.18.1073
Barca Ida, Cordaro Raffaella, C. Walter, Novembre Daniela, G CristofaroMaria
Traumatic Ulcerative granuloma with stromal eosinophilia (TUGSE) is an infrequent condition marked by the presence of a solitary ulcer in the oral mucosa. It is generally considered a reactive, benign and self-limiting ulcer with raised and indurated margins, mainly affecting the tongue, cheeks, or, less frequently, lips. His typical histology shows a diffuse polymorphic cell inflammatory infiltrate composed predominantly of eosinophils involving the superficial mucosa and extending deep into the submucosa with degeneration of the underlying muscle layer. Aetiology is unknown and pathogenesis is not clear although trauma could have an important role in the origin and evolution of this lesion. Nevertheless, a correct diagnosis is difficult because the ulcer mimics a wide range of pathologies including microbial infections or cancer. This work describes a case of traumatic granuloma of the tongue in a child female focusing attention on the differential diagnosis of this unclear lesion
创伤性溃疡性肉芽肿伴间质嗜酸性粒细胞增多(TUGSE)是一种罕见的情况,其特征是口腔粘膜出现孤立性溃疡。它通常被认为是一种反应性的、良性的、自限性的溃疡,边缘凸起和硬化,主要影响舌头、脸颊,或者很少发生的嘴唇。他的典型组织学表现为弥漫性多形态细胞炎性浸润,主要由嗜酸性粒细胞组成,累及浅表粘膜,并深入粘膜下层,伴有下层肌肉层变性。虽然创伤可能在这种病变的起源和发展中起重要作用,但病因不明,发病机制尚不清楚。然而,正确的诊断是困难的,因为溃疡模仿广泛的病理包括微生物感染或癌症。本工作描述了一个病例的创伤性肉芽肿的舌头在一个儿童女性集中注意鉴别诊断这种不明确的病变
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引用次数: 0
Biomechanical Behavior of Tooth-Supported Fixed Partial Prostheses Components with Two Different Infrastructures: Metal and Polyether Ether Ketone (Peek). 金属和聚醚醚酮(Peek)两种不同结构的牙支撑固定部分假体部件的生物力学行为。
Pub Date : 2019-01-01 DOI: 10.35248/2247-2452.19.18.1074
Santos Heloisa RB, ÃƒÂvila Gisseli B, Carvalho Geraldo AP, Ramos Elimário V, Franco Aline BG, Franco Amanda G, D. Sérgio C
This study uses the finite element method to assess the biomechanical behavior of tooth-supported fixed partial prostheses components manufactured with two different infrastructures: Cr-Co Fit Flex metallic alloy and Polyether Ether Ketone (PEEK) subjected to physiological occlusal loads. Two models with equal geometry were simulated-Model M1: fixed partial prosthesis with Cr-Co metallic infrastructure and feldspar ceramics coating Noritake Ex-3; Model M2: fixed partial prosthesis with PEEK infrastructure PEEK and indirect resin coating Sinfony. They were subjected to axial and oblique loads. The 3D models were entered in the software CAD Solidworks 2016 for registry and analysis. Data were analyzed according to the studied factors: dentin behavior, infrastructure, aesthetic coating, detachment pressure between tooth and cement, and tensile stress of cement. Most stress peaks were observed in model M2, but values from the two models were close. Model M1 showed better results in four of the factors: dentin, infrastructure, detachment pressure between tooth and cement, and cement tensile stress. Model M2 showed better performance in terms of the aesthetic coating. Similar values for both models in most of the simulations suggest a long lifespan of both treatments, although longer for model M1.
本研究采用有限元方法评估了两种不同基础材料(Cr-Co Flex金属合金和聚醚醚酮)制造的牙支撑固定部分修复体在生理咬合负荷下的生物力学行为。模拟了两个等几何模型:M1模型:Cr-Co金属结构和长石陶瓷涂层Noritake Ex-3的固定部分假肢;M2型:固定部分假体,以PEEK为基础,PEEK为间接树脂涂层。它们承受轴向和斜向载荷。将三维模型输入CAD Solidworks 2016进行注册和分析。根据研究的因素:牙本质行为、基础设施、美观涂层、牙体与骨水泥之间的脱离压力和骨水泥的拉应力,对数据进行分析。在M2模型中观察到的应力峰值最多,但两个模型的值接近。M1模型在牙本质、基础设施、牙体与骨水泥分离压力、骨水泥拉应力四个方面均有较好的效果。M2型在美观涂层方面表现出更好的性能。在大多数模拟中,两种模型的相似值表明两种处理的寿命都很长,尽管M1模型的寿命更长。
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引用次数: 3
Clinical Therapeutic Usage of Bichat Ball in Dentistry-A Review Bichat球在牙科临床治疗中的应用综述
Pub Date : 2019-01-01 DOI: 10.35248/2247-2452.19.18.1079
Lima Eduardo B, SÁ Carlos DL, Feitosa Victor P, De-Paula Dm, Papaléo Rf, Melo Radamés B
The Bichat ball is fat located in the cheeks region, which can be used for various therapeutic purposes. The aim of the present study is to carry out a literature review on the use of Bichat ball and its application for aesthetic and functional issues. A search was performed on PubMed; SciELO, Scopus and Lilacs databases using the keywords we found 76 articles and 8 were selected, based on exclusion criteria (laboratory studies, articles in a language other than English, and literature reviews). The title and abstract of articles that met the inclusion criteria were evaluated. Some articles mentioned the use of the Bichat ball for the repair of small oral defects, such as oroantral communication closure, peri-orbital defects, congenital cleft palate, facial plastic surgery; some treatments were associated with pathologies. Further articles quoted its use for aesthetic purposes such as facial feminization and diminishing of the child's cheek appearance. Thus, the Bichat ball is effective for various purposes and can be used for both aesthetic and functional therapeutic treatment.
Bichat球是位于脸颊区域的脂肪,可用于各种治疗目的。本研究的目的是对Bichat球的使用及其在美学和功能问题上的应用进行文献综述。在PubMed上进行了搜索;我们在SciELO、Scopus和Lilacs数据库中使用这些关键词发现了76篇文章,根据排除标准(实验室研究、非英语语言的文章和文献综述)选择了8篇。对符合纳入标准的文章的标题和摘要进行评价。一些文章提到使用Bichat球修复口腔小缺损,如口窦交通闭塞、眶周缺损、先天性腭裂、面部整形手术;一些治疗与病理有关。进一步的文章引用了它用于美学目的,如面部女性化和减少儿童的脸颊外观。因此,Bichat球对各种目的都有效,可以用于美学和功能治疗。
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引用次数: 0
The Effect of a Low-Level Laser in the Treatment of Glossopyrosis and Glossodinia 低强度激光治疗舌萎缩和舌裂的效果
Pub Date : 2019-01-01 DOI: 10.35248/2247-2452.19.18.1064
A. Pejčić, I. Minić, R. Obradović, Marijan Bradic
Introduction: Glossodinia and glossospyrosis is characterized by the appearance of symptoms of burning and pain. Sometimes these symptoms of tingling and pain in the tongue can occur even without any pathological changes in the oral cavity. Low-level lasers, used in the therapy of some oral diseases, showed a positive effect after use, and the aim of this paper was to examine whether the analgesic effect of low-level laser has an effect on the reduction of subjective symptoms of burning and pain in the tongue, as well as whether it affects the quality of life of a patient. Material and Methods: The study included 45 patients who came to the Department of Oral Medicine and Periodontology of the Clinic for Dentistry, Faculty of Medicine, Nis. All of them had symptoms of burning and pain in the tongue. Twenty-six patients, randomly selected, in addition to symptomatic, also received low-level laser therapy to lose symptoms of burning and pain. A lowlevel laser KaVo MASTER lases, Biberach, Germany, was used, a wavelength being 980 nm with an output power of 0.2W in continuous mode. Results: Ten patients agreed that the low-level laser reduces the subjective feelings of the dinya and pyrosis. There were no side effects and all patients completed the treatment without interruption. In no case was there any worsening of the symptoms, while 4 patients did not report any improvement. Conclusion: According to the results of this study it can be said that low-level lasers can be used as one of the therapeutic procedures in the treatment of Glossodynia and Glossopyrosis, as well as in improving the quality of life of patients with the same or similar problems.
简介:舌骨和舌骨前旋的特点是出现烧灼和疼痛的症状。有时,即使口腔没有任何病理变化,舌头也会出现刺痛和疼痛的症状。低水平激光用于治疗一些口腔疾病,使用后显示出积极的效果,本文的目的是研究低水平激光的镇痛效果是否对减轻舌头灼烧和疼痛的主观症状有影响,以及是否影响患者的生活质量。材料和方法:本研究纳入45例就诊于尼斯大学医学院牙科门诊口腔医学和牙周病科的患者。他们都有舌头灼烧和疼痛的症状。随机选择26例患者,除有症状外,还接受低水平激光治疗,以消除灼烧和疼痛症状。使用德国Biberach公司的低能级KaVo MASTER激光器,波长为980 nm,连续模式下输出功率为0.2W。结果:10例患者一致认为,低强度激光治疗可减轻疼痛和发热的主观感觉。没有副作用,所有患者都完成了治疗,没有中断。所有病例均无任何症状恶化,4例患者无任何改善。结论:根据本研究结果,可以说低水平激光可以作为治疗舌痛症和舌光肌萎缩的治疗手段之一,并且可以改善有相同或类似问题的患者的生活质量。
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引用次数: 0
期刊
Oral health and dental management
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