首页 > 最新文献

Orthopaedic Surgery最新文献

英文 中文
Oblique Lumbar Interbody Fusion Combined With Anterolateral Fixation and Cement Augmentation for the Treatment of Degenerative Lumbar Diseases in the Elderly Population: A Retrospective Study. 斜腰椎椎体间融合联合前外侧固定和骨水泥增强治疗老年人退行性腰椎疾病的回顾性研究
IF 1.8 2区 医学 Q2 ORTHOPEDICS Pub Date : 2025-02-01 Epub Date: 2024-12-03 DOI: 10.1111/os.14315
Weiqi Han, Lei He, Fei Wang, Xiaofeng Zhao, Cong Jin

Objectives: Cage subsidence is a common complication of oblique lumbar interbody fusion (OLIF), particularly in elderly patients with osteoporosis or osteopenia. While bilateral pedicle screw fixation (BPS) is effective in reducing subsidence, it is associated with longer operative times, increased blood loss, and greater tissue trauma. In contrast, anterolateral fixation (AF) is less invasive but linked to higher subsidence rates. Ensuring both minimal invasiveness and adequate stability in OLIF-assisted fixation remains a significant challenge. This study aimed to evaluate the efficacy of combining AF with cement augmentation (AF + CA) in reducing cage subsidence and improving clinical outcomes compared with AF and BPS.

Methods: A retrospective analysis was conducted on 138 elderly patients with degenerative lumbar diseases treated with OLIF. Patients were divided into three groups: AF + CA (32 patients), AF (32 patients), and BPS (74 patients). Clinical and radiographic outcomes were compared among the groups, and logistic regression analyses were performed to identify risk factors for cage subsidence after OLIF.

Results: At 1 year postoperatively, the disc height of the AF + CA group was significantly greater than that of the AF group. The cage subsidence rate in the AF + CA group was 24.3%, significantly lower than that in the AF group (48.8%, p < 0.05) and comparable to the BPS group (30.4%). Survivorship curve analysis showed better outcomes in reducing cage subsidence in the AF + CA group compared with the AF group, with no significant difference between the AF + CA and BPS groups. Compared with the AF + CA and BPS groups, the AF group had significantly higher grades and severity of cage subsidence. Fusion rates at 1 year were 91.9% in the AF + CA group, 90.2% in the AF group, and 95.1% in the BPS group, with no significant differences. The AF + CA group had significantly shorter operative times, less intraoperative blood loss, lower VAS scores at 3 days and 1 year postoperatively, and lower ODI scores at 3 days and 3 months compared with the BPS group. Multivariate regression analysis revealed that AF was a significant risk factor for cage subsidence, with an odds ratio of 3.399 compared with AF + CA.

Conclusions: AF + CA effectively reduces cage subsidence in OLIF surgeries, offering results comparable to BPS while providing advantages such as shorter surgical time, reduced blood loss, and improved early postoperative outcomes. AF + CA is a viable alternative, especially for elderly patients with comorbidities who may not tolerate the longer operative durations or greater blood loss associated with BPS.

目的:椎笼下沉是斜腰椎体间融合术(OLIF)的常见并发症,尤其是老年骨质疏松或骨质减少患者。虽然双侧椎弓根螺钉固定(BPS)可以有效地减少沉陷,但它会增加手术时间、出血量和更大的组织损伤。相比之下,前外侧固定(AF)侵入性较小,但与较高的沉降率有关。在olif辅助下确保最小的侵入性和足够的稳定性仍然是一个重大的挑战。本研究旨在评估AF联合水泥增强(AF + CA)与AF和BPS相比在减少笼型下沉和改善临床结果方面的疗效。方法:对138例老年退行性腰椎疾病行OLIF治疗的患者进行回顾性分析。患者分为三组:AF + CA(32例)、AF(32例)和BPS(74例)。比较各组的临床和影像学结果,并进行logistic回归分析,以确定OLIF后笼子下沉的危险因素。结果:术后1年,AF + CA组椎间盘高度明显大于AF组。AF + CA组的轿厢下沉率为24.3%,明显低于AF组(48.8%)。p结论:AF + CA有效降低OLIF手术中的轿厢下沉,效果与BPS相当,同时具有缩短手术时间、减少出血量、改善术后早期预后等优势。AF + CA是一种可行的替代方案,特别是对于有合并症的老年患者,他们可能无法忍受与BPS相关的更长的手术时间或更大的出血量。
{"title":"Oblique Lumbar Interbody Fusion Combined With Anterolateral Fixation and Cement Augmentation for the Treatment of Degenerative Lumbar Diseases in the Elderly Population: A Retrospective Study.","authors":"Weiqi Han, Lei He, Fei Wang, Xiaofeng Zhao, Cong Jin","doi":"10.1111/os.14315","DOIUrl":"10.1111/os.14315","url":null,"abstract":"<p><strong>Objectives: </strong>Cage subsidence is a common complication of oblique lumbar interbody fusion (OLIF), particularly in elderly patients with osteoporosis or osteopenia. While bilateral pedicle screw fixation (BPS) is effective in reducing subsidence, it is associated with longer operative times, increased blood loss, and greater tissue trauma. In contrast, anterolateral fixation (AF) is less invasive but linked to higher subsidence rates. Ensuring both minimal invasiveness and adequate stability in OLIF-assisted fixation remains a significant challenge. This study aimed to evaluate the efficacy of combining AF with cement augmentation (AF + CA) in reducing cage subsidence and improving clinical outcomes compared with AF and BPS.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on 138 elderly patients with degenerative lumbar diseases treated with OLIF. Patients were divided into three groups: AF + CA (32 patients), AF (32 patients), and BPS (74 patients). Clinical and radiographic outcomes were compared among the groups, and logistic regression analyses were performed to identify risk factors for cage subsidence after OLIF.</p><p><strong>Results: </strong>At 1 year postoperatively, the disc height of the AF + CA group was significantly greater than that of the AF group. The cage subsidence rate in the AF + CA group was 24.3%, significantly lower than that in the AF group (48.8%, p < 0.05) and comparable to the BPS group (30.4%). Survivorship curve analysis showed better outcomes in reducing cage subsidence in the AF + CA group compared with the AF group, with no significant difference between the AF + CA and BPS groups. Compared with the AF + CA and BPS groups, the AF group had significantly higher grades and severity of cage subsidence. Fusion rates at 1 year were 91.9% in the AF + CA group, 90.2% in the AF group, and 95.1% in the BPS group, with no significant differences. The AF + CA group had significantly shorter operative times, less intraoperative blood loss, lower VAS scores at 3 days and 1 year postoperatively, and lower ODI scores at 3 days and 3 months compared with the BPS group. Multivariate regression analysis revealed that AF was a significant risk factor for cage subsidence, with an odds ratio of 3.399 compared with AF + CA.</p><p><strong>Conclusions: </strong>AF + CA effectively reduces cage subsidence in OLIF surgeries, offering results comparable to BPS while providing advantages such as shorter surgical time, reduced blood loss, and improved early postoperative outcomes. AF + CA is a viable alternative, especially for elderly patients with comorbidities who may not tolerate the longer operative durations or greater blood loss associated with BPS.</p>","PeriodicalId":19566,"journal":{"name":"Orthopaedic Surgery","volume":" ","pages":"446-459"},"PeriodicalIF":1.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11787981/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142770970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Key Decision-Making in Post-Failed Internal Fixation of Intertrochanteric Fractures Hip Arthroplasty: A Multicenter Retrospective Study on Fracture Healing's Impact on Femoral Component Selection. 股骨粗隆间骨折置换术内固定失败后的关键决策:骨折愈合对股骨假体选择影响的多中心回顾性研究。
IF 1.8 2区 医学 Q2 ORTHOPEDICS Pub Date : 2025-02-01 Epub Date: 2024-12-05 DOI: 10.1111/os.14303
Jiexin Huang, Jiagu Huang, Haiqi Ding, Jianhua Lyu, Changyu Huang, Yang Chen, Qijin Wang, Hongyan Li, Baijian Wu, Ying Huang, Minghui Yang, Xinyu Fang, Wenming Zhang

Purpose: Following failed internal fixation of intertrochanteric fractures (FIF-ITF), the decision to use a long-stem or standard-stem femoral implant in hip arthroplasty is still debated. This study aimed to explore how the healing status of fractures after FIF-ITF failure affects the choice of femoral stem and clinical outcomes.

Methods: Our retrospective cohort study reviewed 105 cases of patients with FIF-ITF who underwent hip arthroplasty at three tertiary Grade A hospitals between December 2012 and December 2022. We compared the clinical outcomes between patients with healed and unhealed fractures, focusing on the selection of femoral stems in relation to proximal medial support and the healing status of the greater trochanter. The primary outcomes measured were functional results, operative time, blood loss, and incidence of complications. A subgroup analysis was conducted to further evaluate the influence of the proximal medial buttress and greater trochanteric healing on femoral stem selection. Statistical analysis included binary and ordinal logistic regression to identify factors influencing the choice of femoral stems. Additionally, a decision tree model was developed to visually represent and explore the relationship between fracture healing status and the selection of femoral components.

Results: The study included 38 patients with healed fractures and 67 patients with unhealed fractures. Patients in the healed group predominantly chose standard stems and experienced better functional outcomes (p < 0.001, p = 0.002). In contrast, the unhealed group preferred long stems, resulting in longer surgical durations and increased blood loss (p = 0.008, p < 0.001). Binary logistic regression analysis revealed that nonunion of the proximal femoral medial buttress was an independent risk factor for long stems (p < 0.0001, OR = 10.402).

Conclusion: The selection of femoral prostheses following FIF-ITF is influenced by the fracture healing status, particularly the presence of proximal femoral medial buttress. The decision tree model suggested that long-stem prostheses are more appropriate when there is inadequate fracture healing and the proximal femoral medial buttress is absent.

目的:在股骨粗隆间骨折(FIF-ITF)内固定失败后,在髋关节置换术中使用长柄或标准柄股骨假体的决定仍存在争议。本研究旨在探讨FIF-ITF失败后骨折的愈合状况如何影响股骨干的选择和临床结果。方法:回顾性队列研究回顾了2012年12月至2022年12月在三家三甲医院行髋关节置换术的105例FIF-ITF患者。我们比较了愈合和未愈合骨折患者的临床结果,重点关注股骨干选择与近端内侧支撑和大转子愈合状况的关系。测量的主要结果是功能结果、手术时间、出血量和并发症发生率。通过亚组分析进一步评估近端内侧支撑和大转子愈合对股骨干选择的影响。统计分析包括二元和有序逻辑回归,以确定影响选择股骨干的因素。此外,我们还开发了决策树模型来直观地表示和探索骨折愈合状态与股骨假体选择之间的关系。结果:38例骨折愈合,67例骨折未愈合。愈合组患者主要选择标准假体,其功能预后较好(p结论:FIF-ITF术后股骨假体的选择受骨折愈合状况的影响,尤其是股骨近端内侧支撑的存在。决策树模型表明,当骨折愈合不充分且股骨近端内侧支撑缺失时,长柄假体更为合适。
{"title":"Key Decision-Making in Post-Failed Internal Fixation of Intertrochanteric Fractures Hip Arthroplasty: A Multicenter Retrospective Study on Fracture Healing's Impact on Femoral Component Selection.","authors":"Jiexin Huang, Jiagu Huang, Haiqi Ding, Jianhua Lyu, Changyu Huang, Yang Chen, Qijin Wang, Hongyan Li, Baijian Wu, Ying Huang, Minghui Yang, Xinyu Fang, Wenming Zhang","doi":"10.1111/os.14303","DOIUrl":"10.1111/os.14303","url":null,"abstract":"<p><strong>Purpose: </strong>Following failed internal fixation of intertrochanteric fractures (FIF-ITF), the decision to use a long-stem or standard-stem femoral implant in hip arthroplasty is still debated. This study aimed to explore how the healing status of fractures after FIF-ITF failure affects the choice of femoral stem and clinical outcomes.</p><p><strong>Methods: </strong>Our retrospective cohort study reviewed 105 cases of patients with FIF-ITF who underwent hip arthroplasty at three tertiary Grade A hospitals between December 2012 and December 2022. We compared the clinical outcomes between patients with healed and unhealed fractures, focusing on the selection of femoral stems in relation to proximal medial support and the healing status of the greater trochanter. The primary outcomes measured were functional results, operative time, blood loss, and incidence of complications. A subgroup analysis was conducted to further evaluate the influence of the proximal medial buttress and greater trochanteric healing on femoral stem selection. Statistical analysis included binary and ordinal logistic regression to identify factors influencing the choice of femoral stems. Additionally, a decision tree model was developed to visually represent and explore the relationship between fracture healing status and the selection of femoral components.</p><p><strong>Results: </strong>The study included 38 patients with healed fractures and 67 patients with unhealed fractures. Patients in the healed group predominantly chose standard stems and experienced better functional outcomes (p < 0.001, p = 0.002). In contrast, the unhealed group preferred long stems, resulting in longer surgical durations and increased blood loss (p = 0.008, p < 0.001). Binary logistic regression analysis revealed that nonunion of the proximal femoral medial buttress was an independent risk factor for long stems (p < 0.0001, OR = 10.402).</p><p><strong>Conclusion: </strong>The selection of femoral prostheses following FIF-ITF is influenced by the fracture healing status, particularly the presence of proximal femoral medial buttress. The decision tree model suggested that long-stem prostheses are more appropriate when there is inadequate fracture healing and the proximal femoral medial buttress is absent.</p>","PeriodicalId":19566,"journal":{"name":"Orthopaedic Surgery","volume":" ","pages":"470-481"},"PeriodicalIF":1.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11787966/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142786179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Computer-Aided High Tibial Osteotomy-A Comparative Study of Commonly Used 3D Printing Technology and Navigation Application. 计算机辅助胫骨高位截骨术——常用3D打印技术与导航应用的比较研究。
IF 1.8 2区 医学 Q2 ORTHOPEDICS Pub Date : 2025-02-01 Epub Date: 2024-12-23 DOI: 10.1111/os.14274
Elvis Chun-Sing Chui, Kyle Ka-Kwan Mak, Randy Hin-Ting Ng, Ericsson Chun-Hai Fung, Mei-Shuen Chan, Kai Yue, Lawrence Chun-Man Lau, Clifford Long-Fung Chan, Edmond Wing-Fung Yau, Wei Zhao, Xiuyun Su, Jin Zhang, Jianglong Xu, Hongxun Sang, Guoxian Pei, Louis Wing-Hoi Cheung, Sheung-Wai Law, Michael Tim-Yun Ong, Patrick Shu-Hang Yung

Background: High tibial osteotomy (HTO) is a surgical procedure for treating certain knee conditions. Proper execution of HTO can preserve joint function and delay or avoid the need for total knee replacement. This study compared different 3D printing techniques (fused deposition modeling, selective laser sintering, and direct metal laser sintering) and a navigation system for their suitability in assisting HTO surgeries.

Methods: Tibial saw-bones were used as models, and surgical guides and the navigation system were employed during the procedures. Six parameters (planning time, manufacturing time, delivery time, material cost, operation time, and accuracy) were evaluated. One-way analysis of variance (ANOVA) and t-test were used for the analysis.

Results: The results showed that the metal surgical guides had the highest accuracy (angle differences mean, 2.4°) and operation time (mean 9.75 min), followed by plastic guides, classic guides, and the navigation system. The differences in accuracy were attributed to factors like rigidity, melting point, and errors during incisions.

Conclusions: The study recommended metal surgical guides as the best option for assisting HTO due to their accuracy and operation time. And the results have implications for orthopedic surgeons performing HTO surgeries, as they can use this information to improve postoperative outcomes, such as mechanical axis alignment and quality of life for HTO patients.

背景:胫骨高位截骨术(HTO)是一种治疗某些膝关节疾病的外科手术。正确执行HTO可以保留关节功能,延迟或避免全膝关节置换术的需要。本研究比较了不同的3D打印技术(熔融沉积建模、选择性激光烧结和直接金属激光烧结)和导航系统,以确定它们在辅助HTO手术中的适用性。方法:以胫骨锯骨为模型,在手术过程中使用手术指南和导航系统。评估六个参数(计划时间、制造时间、交货时间、材料成本、操作时间和精度)。分析采用单因素方差分析(ANOVA)和t检验。结果:结果表明,金属手术台精度最高(平均角度差2.4°),手术时间最长(平均9.75 min),其次为塑料手术台、经典手术台和导航系统。准确性的差异归因于诸如刚性,熔点和切口时的误差等因素。结论:本研究推荐金属手术指南作为辅助HTO的最佳选择,因为其准确性和手术时间。研究结果对实施HTO手术的骨科医生有启示意义,因为他们可以利用这些信息来改善术后结果,如机械轴对齐和HTO患者的生活质量。
{"title":"Computer-Aided High Tibial Osteotomy-A Comparative Study of Commonly Used 3D Printing Technology and Navigation Application.","authors":"Elvis Chun-Sing Chui, Kyle Ka-Kwan Mak, Randy Hin-Ting Ng, Ericsson Chun-Hai Fung, Mei-Shuen Chan, Kai Yue, Lawrence Chun-Man Lau, Clifford Long-Fung Chan, Edmond Wing-Fung Yau, Wei Zhao, Xiuyun Su, Jin Zhang, Jianglong Xu, Hongxun Sang, Guoxian Pei, Louis Wing-Hoi Cheung, Sheung-Wai Law, Michael Tim-Yun Ong, Patrick Shu-Hang Yung","doi":"10.1111/os.14274","DOIUrl":"10.1111/os.14274","url":null,"abstract":"<p><strong>Background: </strong>High tibial osteotomy (HTO) is a surgical procedure for treating certain knee conditions. Proper execution of HTO can preserve joint function and delay or avoid the need for total knee replacement. This study compared different 3D printing techniques (fused deposition modeling, selective laser sintering, and direct metal laser sintering) and a navigation system for their suitability in assisting HTO surgeries.</p><p><strong>Methods: </strong>Tibial saw-bones were used as models, and surgical guides and the navigation system were employed during the procedures. Six parameters (planning time, manufacturing time, delivery time, material cost, operation time, and accuracy) were evaluated. One-way analysis of variance (ANOVA) and t-test were used for the analysis.</p><p><strong>Results: </strong>The results showed that the metal surgical guides had the highest accuracy (angle differences mean, 2.4°) and operation time (mean 9.75 min), followed by plastic guides, classic guides, and the navigation system. The differences in accuracy were attributed to factors like rigidity, melting point, and errors during incisions.</p><p><strong>Conclusions: </strong>The study recommended metal surgical guides as the best option for assisting HTO due to their accuracy and operation time. And the results have implications for orthopedic surgeons performing HTO surgeries, as they can use this information to improve postoperative outcomes, such as mechanical axis alignment and quality of life for HTO patients.</p>","PeriodicalId":19566,"journal":{"name":"Orthopaedic Surgery","volume":" ","pages":"593-602"},"PeriodicalIF":1.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11787984/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142876900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fracture Line Morphology and a Novel Classification of Pilon Fractures. 骨折线形态学和 Pilon 骨折的新分类。
IF 1.8 2区 医学 Q2 ORTHOPEDICS Pub Date : 2025-02-01 Epub Date: 2024-11-23 DOI: 10.1111/os.14304
Jichao Liu, Chengdong Piao, Guanlu Cui, Haipeng Sun, Zhengwei Li
<p><strong>Objective: </strong>Currently, there is no research that includes a comprehensive three-dimensional fracture mapping encompassing all types of Pilon fractures. Moreover, the existing classification systems for Pilon fractures exhibit only moderate to fair consistency and reproducibility. Additionally, some of these classification systems fail to accurately depict the morphological characteristics of the fractures. This study aimed to create a fracture map encompassing all types of Pilon fractures by three-dimensional fracture mapping. In addition, this study conducted a finite element analysis of the normal ankle joint, and based on the distribution of fracture lines and the stress distribution at the distal tibia, proposed a new classification for Pilon fractures.</p><p><strong>Methods: </strong>A retrospective analysis of Pilon fractures in our hospital from January 2018 to January 2024 was performed. A total of two hundred forty-four Pilon fractures were included, and their fracture lines were transcribed onto the tibia and fibula templates, and fracture maps and heat maps were created. A nonhomogeneous model of the ankle joint was constructed and verified, and the stress distribution on the distal tibia articular surface was measured and analyzed in three models (neutral, dorsiflexed, and plantarflexed model). Based on the fracture map and stress distribution, a five-column classification system for Pilon fractures was proposed, and the intraobserver and interobserver reliability was calculated using Cohen and Fleiss k statistics.</p><p><strong>Result: </strong>The fracture line on the distal tibia articular surface showed a V-shaped distribution. One branch extended from the junction of the medial malleolar articular surface and the inferior tibial articular surface toward the medial malleolus. The other branch extended from the middle of the fibular notch to the posterior part of the medial ankle, toward the tibial shaft. The fibula fracture line mainly extended from the anterior and lower part of the lateral malleolus to the posterior and upper part. As evidenced by the neutral, dorsiflexed, and plantar flexion models, the stress on the posterolateral articular surface (posterolateral column) was low, while the majority of the stress was concentrated in the center. Three-column fractures were the most common, followed by two-column fractures. Using the five-column classification, the K-weighted values of interobserver and intraobserver analysis were 0.653 (p < 0.001) and 0.708 (p < 0.001), respectively.</p><p><strong>Conclusions: </strong>In this study, the fracture line and morphological characteristics of Pilon fractures were analyzed in detail by three-dimensional mapping. In addition, this study conducted a finite element analysis of the stress distribution on the distal tibial joint surface of the normal ankle joint. Moreover, a novel classification system was proposed to reflect these findings. The new classification not o
目的:目前,还没有包括所有类型 Pilon 骨折的全面三维骨折图谱的研究。此外,现有的 Pilon 骨折分类系统仅表现出中等至一般的一致性和可重复性。此外,其中一些分类系统未能准确描述骨折的形态特征。本研究旨在通过绘制三维断裂图,绘制一张包含所有类型 Pilon 断裂的断裂图。此外,本研究还对正常踝关节进行了有限元分析,并根据骨折线的分布和胫骨远端应力分布,提出了 Pilon 骨折的新分类方法:对我院2018年1月至2024年1月的Pilon骨折进行回顾性分析。共纳入 244 例 Pilon 骨折,将其骨折线转录到胫骨和腓骨模板上,并绘制骨折图和热图。构建并验证了踝关节的非均质模型,测量并分析了三种模型(中立、背屈和跖屈模型)中胫骨远端关节面上的应力分布。根据骨折图和应力分布,提出了 Pilon 骨折的五列分类系统,并使用 Cohen 和 Fleiss k 统计法计算了观察者内和观察者间的可靠性:结果:胫骨远端关节面的骨折线呈 V 形分布。一个分支从内侧踝关节面和胫骨下端关节面交界处向内侧踝骨延伸,另一个分支从胫骨下端关节面中部向内侧踝骨延伸。另一分支从腓骨切迹中部向内踝后部延伸,朝向胫骨轴。腓骨骨折线主要从外侧踝骨的前下方向后上方延伸。从中立位、背屈位和跖屈位模型可以看出,后外侧关节面(后外侧柱)的应力较低,而大部分应力集中在中心位置。三柱骨折最常见,其次是两柱骨折。采用五柱分类法,观察者间和观察者内分析的 K 加权值均为 0.653(p 结论):本研究通过三维绘图详细分析了 Pilon 骨折的骨折线和形态特征。此外,本研究还对正常踝关节胫骨远端关节面的应力分布进行了有限元分析。此外,研究还提出了一个新的分类系统来反映这些发现。新的分类方法不仅具有更强的一致性,便于外科医生准确交流骨折特征,而且有助于了解损伤机制和制定手术策略。
{"title":"Fracture Line Morphology and a Novel Classification of Pilon Fractures.","authors":"Jichao Liu, Chengdong Piao, Guanlu Cui, Haipeng Sun, Zhengwei Li","doi":"10.1111/os.14304","DOIUrl":"10.1111/os.14304","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;Currently, there is no research that includes a comprehensive three-dimensional fracture mapping encompassing all types of Pilon fractures. Moreover, the existing classification systems for Pilon fractures exhibit only moderate to fair consistency and reproducibility. Additionally, some of these classification systems fail to accurately depict the morphological characteristics of the fractures. This study aimed to create a fracture map encompassing all types of Pilon fractures by three-dimensional fracture mapping. In addition, this study conducted a finite element analysis of the normal ankle joint, and based on the distribution of fracture lines and the stress distribution at the distal tibia, proposed a new classification for Pilon fractures.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A retrospective analysis of Pilon fractures in our hospital from January 2018 to January 2024 was performed. A total of two hundred forty-four Pilon fractures were included, and their fracture lines were transcribed onto the tibia and fibula templates, and fracture maps and heat maps were created. A nonhomogeneous model of the ankle joint was constructed and verified, and the stress distribution on the distal tibia articular surface was measured and analyzed in three models (neutral, dorsiflexed, and plantarflexed model). Based on the fracture map and stress distribution, a five-column classification system for Pilon fractures was proposed, and the intraobserver and interobserver reliability was calculated using Cohen and Fleiss k statistics.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Result: &lt;/strong&gt;The fracture line on the distal tibia articular surface showed a V-shaped distribution. One branch extended from the junction of the medial malleolar articular surface and the inferior tibial articular surface toward the medial malleolus. The other branch extended from the middle of the fibular notch to the posterior part of the medial ankle, toward the tibial shaft. The fibula fracture line mainly extended from the anterior and lower part of the lateral malleolus to the posterior and upper part. As evidenced by the neutral, dorsiflexed, and plantar flexion models, the stress on the posterolateral articular surface (posterolateral column) was low, while the majority of the stress was concentrated in the center. Three-column fractures were the most common, followed by two-column fractures. Using the five-column classification, the K-weighted values of interobserver and intraobserver analysis were 0.653 (p &lt; 0.001) and 0.708 (p &lt; 0.001), respectively.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;In this study, the fracture line and morphological characteristics of Pilon fractures were analyzed in detail by three-dimensional mapping. In addition, this study conducted a finite element analysis of the stress distribution on the distal tibial joint surface of the normal ankle joint. Moreover, a novel classification system was proposed to reflect these findings. The new classification not o","PeriodicalId":19566,"journal":{"name":"Orthopaedic Surgery","volume":" ","pages":"540-550"},"PeriodicalIF":1.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11787965/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142693260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biomechanical Effects of Different Spacing Distributions Between the Cemented Superior Boundary and Surgical Vertebral Superior Endplates After Percutaneous Vertebroplasty for Osteoporotic Vertebral Compression Fractures: A Three-Dimensional Finite Element Analysis. 经皮椎体成形术治疗骨质疏松性椎体压缩骨折后,骨水泥上界与手术椎体上内板之间不同间距分布的生物力学效应:三维有限元分析。
IF 1.8 2区 医学 Q2 ORTHOPEDICS Pub Date : 2025-02-01 Epub Date: 2024-11-11 DOI: 10.1111/os.14292
Xiao Meng, Chengqiang Zhou, Yifeng Liao, Haibin Zhou, Hua Li, Jiayuan Liu, Xuebin Tang, Yunqing Wang

Objective: Patients with osteoporotic vertebral compression fractures (OVCF) treated with vertebroplasty (PVP) are experiencing an increasing number of problems such as pain recurrence, mainly due to recompression fractures of the operated vertebral body within a certain period of time after the operation, which is closely related to the distribution of intraoperative bone cement. The aim of this study is to investigate the effect of different spacing distributions between the upper boundary of the cement and the upper endplate of the operated vertebra on the biomechanics of the operated vertebra after percutaneous vertebroplasty for OVCF using finite element analysis (FEA).

Methods: One patient with L1 vertebral body OVCF was selected, and computed tomography (CT) of the thoracolumbar segment was performed. The CT data were extracted to establish an FEA model of the T12-L2 vertebral bodies. Bone cement was injected into the L1 vertebral body. Based on the spacing between the upper boundary of the bone cement and the vertebral body's upper endplates, the model vertebrae were divided into 0, 2, 4, and 6 mm spacing groups, and the human body's upright, flexion-extension, lateral flexion, and rotational positions were simulated. The biomechanical effects of different spacing distributions on the postoperative L1 vertebral body and the injected bone cement were evaluated.

Results: In this paper, we found that the Von Mises stress of the L1 vertebrae was the smallest when the spacing between the upper boundary of the bone cement and the vertebral body's upper endplates was 0 mm. The larger the spacing in a certain range between the upper boundary of the bone cement and the vertebral body's upper endplates, the greater the Von Mises stress of the L1 vertebrae. However, in the stress comparison of the injected bone cement, the Von Mises stress of the bone cement was greatest when the spacing between the upper boundary of the bone cement and the upper endplate of the vertebral body was 0 mm; the larger the spacing, the smaller the Von Mises stress.

Conclusion: When the contact spacing between the upper boundary of the bone cement and the upper endplate of the vertebral body is 0 mm, it can effectively eliminate and transfer the pressure caused by the load, thus reducing the stress on the cancellous bone and further reducing the risk of vertebral refracture after surgery.

目的:接受椎体成形术(PVP)治疗的骨质疏松性椎体压缩骨折(OVCF)患者出现疼痛复发等问题越来越多,主要原因是术后一段时间内手术椎体再次发生压缩骨折,这与术中骨水泥的分布密切相关。本研究旨在利用有限元分析(FEA)探讨骨水泥上界与手术椎体上终板之间不同间距分布对经皮椎体成形术治疗 OVCF 术后手术椎体生物力学的影响:方法: 选择一名 L1 椎体 OVCF 患者,对其胸腰椎段进行计算机断层扫描(CT)。提取 CT 数据,建立 T12-L2 椎体的有限元分析模型。将骨水泥注入 L1 椎体。根据骨水泥上边界与椎体上终板之间的间距,将模型椎体分为 0、2、4 和 6 毫米间距组,模拟人体直立、屈伸、侧屈和旋转位置。评估了不同间距分布对术后 L1 椎体和注入骨水泥的生物力学影响:本文发现,当骨水泥上边界与椎体上端板之间的间距为 0 mm 时,L1 椎体的 Von Mises 应力最小。在一定范围内,骨水泥上边界与椎体上终板之间的间距越大,L1 椎体的 Von Mises 应力越大。然而,在注入骨水泥的应力比较中,当骨水泥上边界与椎体上终板之间的间距为 0 mm 时,骨水泥的 Von Mises 应力最大;间距越大,Von Mises 应力越小:结论:当骨水泥上边界与椎体上终板之间的接触间距为 0 mm 时,可有效消除和转移负荷所产生的压力,从而降低松质骨的应力,进一步降低术后椎体折断的风险。
{"title":"Biomechanical Effects of Different Spacing Distributions Between the Cemented Superior Boundary and Surgical Vertebral Superior Endplates After Percutaneous Vertebroplasty for Osteoporotic Vertebral Compression Fractures: A Three-Dimensional Finite Element Analysis.","authors":"Xiao Meng, Chengqiang Zhou, Yifeng Liao, Haibin Zhou, Hua Li, Jiayuan Liu, Xuebin Tang, Yunqing Wang","doi":"10.1111/os.14292","DOIUrl":"10.1111/os.14292","url":null,"abstract":"<p><strong>Objective: </strong>Patients with osteoporotic vertebral compression fractures (OVCF) treated with vertebroplasty (PVP) are experiencing an increasing number of problems such as pain recurrence, mainly due to recompression fractures of the operated vertebral body within a certain period of time after the operation, which is closely related to the distribution of intraoperative bone cement. The aim of this study is to investigate the effect of different spacing distributions between the upper boundary of the cement and the upper endplate of the operated vertebra on the biomechanics of the operated vertebra after percutaneous vertebroplasty for OVCF using finite element analysis (FEA).</p><p><strong>Methods: </strong>One patient with L1 vertebral body OVCF was selected, and computed tomography (CT) of the thoracolumbar segment was performed. The CT data were extracted to establish an FEA model of the T12-L2 vertebral bodies. Bone cement was injected into the L1 vertebral body. Based on the spacing between the upper boundary of the bone cement and the vertebral body's upper endplates, the model vertebrae were divided into 0, 2, 4, and 6 mm spacing groups, and the human body's upright, flexion-extension, lateral flexion, and rotational positions were simulated. The biomechanical effects of different spacing distributions on the postoperative L1 vertebral body and the injected bone cement were evaluated.</p><p><strong>Results: </strong>In this paper, we found that the Von Mises stress of the L1 vertebrae was the smallest when the spacing between the upper boundary of the bone cement and the vertebral body's upper endplates was 0 mm. The larger the spacing in a certain range between the upper boundary of the bone cement and the vertebral body's upper endplates, the greater the Von Mises stress of the L1 vertebrae. However, in the stress comparison of the injected bone cement, the Von Mises stress of the bone cement was greatest when the spacing between the upper boundary of the bone cement and the upper endplate of the vertebral body was 0 mm; the larger the spacing, the smaller the Von Mises stress.</p><p><strong>Conclusion: </strong>When the contact spacing between the upper boundary of the bone cement and the upper endplate of the vertebral body is 0 mm, it can effectively eliminate and transfer the pressure caused by the load, thus reducing the stress on the cancellous bone and further reducing the risk of vertebral refracture after surgery.</p>","PeriodicalId":19566,"journal":{"name":"Orthopaedic Surgery","volume":" ","pages":"373-392"},"PeriodicalIF":1.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11787978/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142625186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Whether the Indications for Reverse Shoulder Arthroplasty Should Continue to Be Expanded? A Systematic Review and Meta-Analysis. 是否应继续扩大反向肩关节置换术的适应症?系统回顾与元分析》。
IF 1.8 2区 医学 Q2 ORTHOPEDICS Pub Date : 2025-02-01 Epub Date: 2024-12-12 DOI: 10.1111/os.14311
Huankun Li, Hangsheng Bao, Zhidong Yang, Baijun Hu, Yaocheng Pan, Yi Wang, Jiayi Chen, Hongjun Chen, Bisheng Shen, Yonggen Zou

Background: It is still unclear whether reverse total shoulder arthroplasty (RTSA) has advantages over traditional hemiarthroplasty (HA) and anatomic total shoulder arthroplasty (ATSA) in the treatment of complex shoulder joint diseases. Therefore, this study aims to evaluate the clinical effectiveness of RTSA in the treatment of complex shoulder joint diseases and further determine whether it is necessary to expand the indications of RTSA.

Method: We conducted a systematic search of studies published between January 1, 2012 and May 31, 2023 in PubMed, Embase, and Cochrane databases. The experimental group included patients who underwent primary reverse total shoulder arthroplasty (RTSA), while the control group consisted of patients who underwent primary hemiarthroplasty (HA) or anatomic total shoulder arthroplasty (ATSA). The minimum follow-up period was 1 year, and a random-effects model was utilized for data synthesis.

Results: A total of 45 studies were included in the meta-analysis. Compare to HA, RTSA showed significant advantages in postoperative ASES scores (p = 0.004), forward flexion (p < 0.0001), and abduction (p < 0.0001). Compare to ATSA, RTSA showed significantly lower postoperative Constant scores (p = 0.004), ASES scores (p = 0.001), SST scores (p < 0.0001), forward flexion (p < 0.0001), abduction (p = 0.011), internal rotation (p < 0.0001), and external rotation (p < 0.0001). Further meta regression analysis was conducted, considering factors such as region, age, gender ratio, and follow-up time, excluding the influence of relevant factors. Overall, RTSA did not demonstrate advantages in postoperative functional scores and range of motion. In terms of complication and revision rates, RTSA had lower rates compared to HA and ATSA, except for the complication rate, where there was no significant difference between RTSA and ATSA (p = 0.521), but statistically significant differences were observed in other measures.

Conclusion: RTSA demonstrates better clinical efficacy compared to HA but is inferior to ATSA. It can be considered for expanding treatment options for elderly patients with 3 or 4-part proximal humeral fractures, but it is not suitable for treating end-stage shoulder arthritis and humeral head necrosis. Overall, the decision to use RTSA should be carefully evaluated based on the extent of the patient's rotator cuff injury.

背景:在复杂肩关节疾病的治疗中,逆行全肩关节置换术(RTSA)是否比传统半关节置换术(HA)和解剖全肩关节置换术(ATSA)有优势尚不清楚。因此,本研究旨在评价RTSA治疗复杂肩关节疾病的临床疗效,并进一步确定是否有必要扩大RTSA的适应症。方法:我们对2012年1月1日至2023年5月31日在PubMed、Embase和Cochrane数据库中发表的研究进行了系统检索。实验组包括接受原发性逆行全肩关节置换术(RTSA)的患者,对照组包括接受原发性半肩关节置换术(HA)或解剖性全肩关节置换术(ATSA)的患者。最小随访期为1年,采用随机效应模型进行数据综合。结果:meta分析共纳入45项研究。与HA相比,RTSA在术后as评分(p = 0.004)、前屈度(p)方面具有显著优势。结论:RTSA的临床疗效优于HA,但不如ATSA。对于肱骨近端有3段或4段骨折的老年患者,可考虑扩大治疗选择,但不适合治疗终末期肩关节关节炎和肱骨头坏死。总的来说,使用RTSA的决定应根据患者肩袖损伤的程度进行仔细评估。
{"title":"Whether the Indications for Reverse Shoulder Arthroplasty Should Continue to Be Expanded? A Systematic Review and Meta-Analysis.","authors":"Huankun Li, Hangsheng Bao, Zhidong Yang, Baijun Hu, Yaocheng Pan, Yi Wang, Jiayi Chen, Hongjun Chen, Bisheng Shen, Yonggen Zou","doi":"10.1111/os.14311","DOIUrl":"10.1111/os.14311","url":null,"abstract":"<p><strong>Background: </strong>It is still unclear whether reverse total shoulder arthroplasty (RTSA) has advantages over traditional hemiarthroplasty (HA) and anatomic total shoulder arthroplasty (ATSA) in the treatment of complex shoulder joint diseases. Therefore, this study aims to evaluate the clinical effectiveness of RTSA in the treatment of complex shoulder joint diseases and further determine whether it is necessary to expand the indications of RTSA.</p><p><strong>Method: </strong>We conducted a systematic search of studies published between January 1, 2012 and May 31, 2023 in PubMed, Embase, and Cochrane databases. The experimental group included patients who underwent primary reverse total shoulder arthroplasty (RTSA), while the control group consisted of patients who underwent primary hemiarthroplasty (HA) or anatomic total shoulder arthroplasty (ATSA). The minimum follow-up period was 1 year, and a random-effects model was utilized for data synthesis.</p><p><strong>Results: </strong>A total of 45 studies were included in the meta-analysis. Compare to HA, RTSA showed significant advantages in postoperative ASES scores (p = 0.004), forward flexion (p < 0.0001), and abduction (p < 0.0001). Compare to ATSA, RTSA showed significantly lower postoperative Constant scores (p = 0.004), ASES scores (p = 0.001), SST scores (p < 0.0001), forward flexion (p < 0.0001), abduction (p = 0.011), internal rotation (p < 0.0001), and external rotation (p < 0.0001). Further meta regression analysis was conducted, considering factors such as region, age, gender ratio, and follow-up time, excluding the influence of relevant factors. Overall, RTSA did not demonstrate advantages in postoperative functional scores and range of motion. In terms of complication and revision rates, RTSA had lower rates compared to HA and ATSA, except for the complication rate, where there was no significant difference between RTSA and ATSA (p = 0.521), but statistically significant differences were observed in other measures.</p><p><strong>Conclusion: </strong>RTSA demonstrates better clinical efficacy compared to HA but is inferior to ATSA. It can be considered for expanding treatment options for elderly patients with 3 or 4-part proximal humeral fractures, but it is not suitable for treating end-stage shoulder arthritis and humeral head necrosis. Overall, the decision to use RTSA should be carefully evaluated based on the extent of the patient's rotator cuff injury.</p>","PeriodicalId":19566,"journal":{"name":"Orthopaedic Surgery","volume":" ","pages":"313-332"},"PeriodicalIF":1.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11787993/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142818762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biomechanical Evaluation of Clival Screw Fixation for Occipitocervical Instablity: A Finite Element Analysis. 椎弓根螺钉固定治疗枕颈不稳的生物力学评估:有限元分析
IF 1.8 2区 医学 Q2 ORTHOPEDICS Pub Date : 2025-02-01 Epub Date: 2024-12-19 DOI: 10.1111/os.14314
Weipeng Lin, Jianying Zheng, Meichao Zhang, Panjie Xu, Hang Xiao, Wei Ji

Objective: The clivus is trapezoidal in shape with uneven bone structure, the optimal number and position of screws for clival fixation are not clear. Therefore, this study aims to explore the optimization clival screw fixation method for occipitocervical instability using finite element analysis.

Methods: Seven finite element models were developed to evaluate biomechanical properties of clival screw fixation for treating occipitocervical stability, including (i) one clival screw fixation A1 and A2 models; (ii) two clival screws fixation B1 and B2 models; (iii) three clival screws fixation C1 and C2 models; (iv) four clival screws fixation D1 model. Loads of 1.5 Nm were applied to the model fRoM different directions to induce flexion, extension, lateral bending, and axial rotation movements.

Results: The regular triangle C1 type three clival screws fixation exhibited great stability, with RoM of 4.20° in flexion, 5.80° in extension, 0.85° in lateral bending, and 1.60° in axial rotation. The peak stress on the internal fixation devices were relatively low, with maximum screw stress of 194 MPa in flexion, 276 MPa in extension, 180 MPa in lateral bending, and 213 MPa in axial rotation; the maximum plate stress were 126, 554, 426, and 378 MPa, respectively. The areas with higher stress were mainly concentrated at the robust neck section of the plate.

Conclusion: The triangular configuration of three clival screws fixation represented the optimized anterior occipitocervical fixation method through the clivus, offering superior biomechanical stability, lower stress on the devices and dispersed stress distribution in the occipitocervical region.

目的:斜坡呈梯形,骨结构不均匀,固定螺钉的最佳数量和位置尚不明确。因此,本研究旨在通过有限元分析探讨枕颈失稳的最佳斜坡螺钉固定方法。方法:建立了7个有限元模型来评估斜坡螺钉固定治疗枕颈稳定性的生物力学特性,包括(i) 1个斜坡螺钉固定A1和A2模型;(ii)两枚斜坡螺钉固定B1和B2模型;(iii)三枚斜坡螺钉固定C1和C2模型;(iv) 4个斜坡螺钉固定D1模型。从不同方向对模型施加1.5 Nm的载荷,诱导模型的屈曲、伸展、侧向弯曲和轴向旋转运动。结果:正三角形C1型三斜坡螺钉固定具有良好的稳定性,屈曲时RoM为4.20°,伸展时RoM为5.80°,侧向弯曲时RoM为0.85°,轴向旋转时RoM为1.60°。内固定装置的峰值应力相对较低,屈曲时最大螺钉应力为194 MPa,伸展时最大螺钉应力为276 MPa,侧向弯曲时最大螺钉应力为180 MPa,轴向旋转时最大螺钉应力为213 MPa;最大板应力分别为126、554、426、378 MPa。应力较大的区域主要集中在板的坚固颈段。结论:三枚斜坡螺钉三角形固定是经斜坡优化的枕颈前路固定方法,具有良好的生物力学稳定性,对器械的应力较小,枕颈区域应力分布分散。
{"title":"Biomechanical Evaluation of Clival Screw Fixation for Occipitocervical Instablity: A Finite Element Analysis.","authors":"Weipeng Lin, Jianying Zheng, Meichao Zhang, Panjie Xu, Hang Xiao, Wei Ji","doi":"10.1111/os.14314","DOIUrl":"10.1111/os.14314","url":null,"abstract":"<p><strong>Objective: </strong>The clivus is trapezoidal in shape with uneven bone structure, the optimal number and position of screws for clival fixation are not clear. Therefore, this study aims to explore the optimization clival screw fixation method for occipitocervical instability using finite element analysis.</p><p><strong>Methods: </strong>Seven finite element models were developed to evaluate biomechanical properties of clival screw fixation for treating occipitocervical stability, including (i) one clival screw fixation A1 and A2 models; (ii) two clival screws fixation B1 and B2 models; (iii) three clival screws fixation C1 and C2 models; (iv) four clival screws fixation D1 model. Loads of 1.5 Nm were applied to the model fRoM different directions to induce flexion, extension, lateral bending, and axial rotation movements.</p><p><strong>Results: </strong>The regular triangle C1 type three clival screws fixation exhibited great stability, with RoM of 4.20° in flexion, 5.80° in extension, 0.85° in lateral bending, and 1.60° in axial rotation. The peak stress on the internal fixation devices were relatively low, with maximum screw stress of 194 MPa in flexion, 276 MPa in extension, 180 MPa in lateral bending, and 213 MPa in axial rotation; the maximum plate stress were 126, 554, 426, and 378 MPa, respectively. The areas with higher stress were mainly concentrated at the robust neck section of the plate.</p><p><strong>Conclusion: </strong>The triangular configuration of three clival screws fixation represented the optimized anterior occipitocervical fixation method through the clivus, offering superior biomechanical stability, lower stress on the devices and dispersed stress distribution in the occipitocervical region.</p>","PeriodicalId":19566,"journal":{"name":"Orthopaedic Surgery","volume":" ","pages":"583-592"},"PeriodicalIF":1.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11787992/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142865051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Novel Algorithm for Surgical Management of Cervical Ossification of Posterior Longitudinal Ligament: A Retrospective Cohort Study With 2-Year Follow-Up. 颈椎后纵韧带骨化手术治疗的新算法:一项为期两年的回顾性队列研究
IF 1.8 2区 医学 Q2 ORTHOPEDICS Pub Date : 2025-02-01 Epub Date: 2024-11-12 DOI: 10.1111/os.14293
Zhuyun Cai, Hui Kang, Lei Quan, Yilong Ren, Meng Fang, Yixuan Tan, Haochen Zhang, Xuhui Zhou, Jun Ma

Object: With the development of new technologies, the surgical algorithm for ossification of posterior longitudinal ligament (OPLL) in the cervical spine also needs to be updated. The aim of this study is to elucidate a new surgical classification algorithm to guide the choice of surgical approaches for cervical OPLL based on its location and extent. In this algorithm, anterior controllable antedisplacement and fusion (ACAF) will be used as a new surgical option.

Methods: This is a single-centered, retrospective, cohort study utilizing a novel algorithm based on the following three criteria: (1) the positional relationship between ossification and uncinate process (UP), (2) the K-line, and (3) the ossification segment for surgical decision-making. Patients diagnosed with cervical OPLL who received surgical intervention guided by the algorithm were included. Patient demographics, Japanese Orthopedic Association (JOA) scores, surgical time, imaging data before and 2 years after surgery, and the occurrence of complications were extracted from the database. Paired t-test was used for intragroup comparison, and one-way ANOVA test was used for the intergroup analyses.

Results: Based on this novel algorithm, 15 patients with Type I, 8 patients with Type II a, 2 patients with Type II b1, 5 patients with Type II b2 were included. The decision-making for the surgical techniques used in each patient followed the recommendation of the novel algorithm. The postoperative JOA scores of all types of patients improved significantly (p < 0.05), and the invasion rates of vertebral canal had also been significantly reduced (p < 0.05). In terms of restoring cervical curvature, patients with Type I (receiving ACAF) and Type II b2 (receiving laminectomy with instrumented fusion) benefited more from surgery (p < 0.05).

Conclusion: A new algorithm guiding the choice of surgical approach for cervical OPLL was validated in a series of 30 patients. Through this analysis, we obtained on their clinical outcomes and complications. ACAF surgery is an ideal choice for Type I patients, with ossification located between UPs, while for patients with ossification exceeding UPs, it is better to perform anterior cervical corpectomy and fusion or posterior surgery.

目的:随着新技术的发展,颈椎后纵韧带骨化(OPLL)的手术算法也需要更新。本研究旨在阐明一种新的手术分类算法,以指导根据颈椎后纵韧带骨化的位置和程度选择手术方法。在该算法中,前路可控反移位融合术(ACAF)将作为一种新的手术选择:这是一项以单一中心、回顾性、队列研究为基础的新算法,该算法基于以下三个标准:(方法:这是一项单一中心的回顾性队列研究,利用基于以下三个标准的新算法:(1)骨化与钩突之间的位置关系;(2)K线;(3)骨化节段,以做出手术决策。纳入了在该算法指导下接受手术治疗的确诊为颈椎OPLL的患者。从数据库中提取了患者的人口统计学资料、日本骨科协会(JOA)评分、手术时间、术前和术后两年的影像学数据以及并发症发生情况。组内比较采用配对 t 检验,组间分析采用单因素方差分析:根据这种新算法,共纳入了 15 例 I 型患者、8 例 II a 型患者、2 例 II b1 型患者和 5 例 II b2 型患者。每位患者的手术决策都遵循了新算法的建议。所有类型患者的术后 JOA 评分均有明显改善(P在 30 例患者中验证了指导选择颈椎 OPLL 手术方法的新算法。通过分析,我们了解了他们的临床疗效和并发症。对于骨化位于UPs之间的I型患者,ACAF手术是理想的选择;而对于骨化超过UPs的患者,最好进行颈椎前路椎体后凸融合术或后路手术。
{"title":"Novel Algorithm for Surgical Management of Cervical Ossification of Posterior Longitudinal Ligament: A Retrospective Cohort Study With 2-Year Follow-Up.","authors":"Zhuyun Cai, Hui Kang, Lei Quan, Yilong Ren, Meng Fang, Yixuan Tan, Haochen Zhang, Xuhui Zhou, Jun Ma","doi":"10.1111/os.14293","DOIUrl":"10.1111/os.14293","url":null,"abstract":"<p><strong>Object: </strong>With the development of new technologies, the surgical algorithm for ossification of posterior longitudinal ligament (OPLL) in the cervical spine also needs to be updated. The aim of this study is to elucidate a new surgical classification algorithm to guide the choice of surgical approaches for cervical OPLL based on its location and extent. In this algorithm, anterior controllable antedisplacement and fusion (ACAF) will be used as a new surgical option.</p><p><strong>Methods: </strong>This is a single-centered, retrospective, cohort study utilizing a novel algorithm based on the following three criteria: (1) the positional relationship between ossification and uncinate process (UP), (2) the K-line, and (3) the ossification segment for surgical decision-making. Patients diagnosed with cervical OPLL who received surgical intervention guided by the algorithm were included. Patient demographics, Japanese Orthopedic Association (JOA) scores, surgical time, imaging data before and 2 years after surgery, and the occurrence of complications were extracted from the database. Paired t-test was used for intragroup comparison, and one-way ANOVA test was used for the intergroup analyses.</p><p><strong>Results: </strong>Based on this novel algorithm, 15 patients with Type I, 8 patients with Type II a, 2 patients with Type II b1, 5 patients with Type II b2 were included. The decision-making for the surgical techniques used in each patient followed the recommendation of the novel algorithm. The postoperative JOA scores of all types of patients improved significantly (p < 0.05), and the invasion rates of vertebral canal had also been significantly reduced (p < 0.05). In terms of restoring cervical curvature, patients with Type I (receiving ACAF) and Type II b2 (receiving laminectomy with instrumented fusion) benefited more from surgery (p < 0.05).</p><p><strong>Conclusion: </strong>A new algorithm guiding the choice of surgical approach for cervical OPLL was validated in a series of 30 patients. Through this analysis, we obtained on their clinical outcomes and complications. ACAF surgery is an ideal choice for Type I patients, with ossification located between UPs, while for patients with ossification exceeding UPs, it is better to perform anterior cervical corpectomy and fusion or posterior surgery.</p>","PeriodicalId":19566,"journal":{"name":"Orthopaedic Surgery","volume":" ","pages":"393-400"},"PeriodicalIF":1.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11787990/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142625200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Subcutaneous Pectoral Edema After Arthroscopic Labral Repair Despite Normal Irrigation Fluid Usage and Surgery Duration. 关节镜下唇部修复后的胸皮下水肿,尽管正常的冲洗液使用和手术时间。
IF 1.8 2区 医学 Q2 ORTHOPEDICS Pub Date : 2025-02-01 Epub Date: 2025-01-15 DOI: 10.1111/os.14324
İnci Hazal Ayas, Yağız Oğul Akcan, Miray Haspolat, Mehmet Ali Tokgöz, İlke Keser, Ulunay Kanatlı

Objectives: Edema after shoulder arthroscopic surgery poses concerns due to its potential complications such as compartment syndrome, nerve damage, and respiratory issues. This study aimed to investigate the acute accumulation of subcutaneous fluid after shoulder arthroscopy.

Methods: A prospective cohort study, providing Level III evidence was conducted on 50 patients undergoing arthroscopic shoulder surgery under interscalene block anaesthesia from September to December 2023. The patients were divided into two groups: rotator cuff repair (RCR, n = 29) and labral repair for shoulder instability (LR, n = 21). Subcutaneous fluid levels were measured preoperatively, postoperatively, and at discharge (24 h postsurgery) using the MoistureMeterD Compact at the neck, pectoral region, deltoid area, cubital fossa, and carpal tunnel. Data on surgery duration and irrigation fluid volume were documented. In the statistical analysis, repeated measures ANOVA and the independent-samples t-test were applied to compare parametric data, while the Friedman test and Mann-Whitney U test were used for nonparametric data.

Results: The average operation time was 29.0 ± 12.1 min for RCR and 30.0 ± 10.9 min for LR, with average irrigation fluid use of 3.8 ± 0.9 and 4.0 ± 0.7 L, respectively (both p > 0.05). There was no increase in subcutaneous edema in the neck and deltoid region in both groups. At discharge, the percentage of subcutaneous fluid increased in the cubital fossa (p = 0.04 for RCR; p < 0.001 for LR) and carpal tunnel (both p < 0.001) in oth groups, whereas pectoral edema increased only in the labral repair group (p = 0.04).

Conclusions: Subcutaneous pectoral edema can occur following arthroscopic labral repair, and increased fluid levels in the cubital fossa and carpal tunnel were observed in both rotator cuff and labral repairs, even in the absence of prolonged surgery or excessive irrigation fluid use. These findings highlight the need for careful postoperative management of edema after shoulder arthroscopy, particularly for labral repairs, with special attention to the pectoral region, cubital fossa, and carpal tunnel to prevent potential complications. The registry is sponsored by the United States National Library of Medicine (www.

Clinicaltrials: gov); Registry Name: Examination of Edema After Arthroscopic Shoulder Surgery ID: NCT06014203.

目的:肩关节镜手术后的水肿由于其潜在的并发症如隔室综合征、神经损伤和呼吸问题而引起关注。本研究旨在探讨肩关节镜术后急性皮下积液。方法:对2023年9月至12月在斜角肌间阻滞麻醉下接受关节镜肩关节手术的50例患者进行前瞻性队列研究,提供III级证据。患者分为两组:肩袖修复组(RCR, n = 29)和肩关节不稳定的唇侧修复组(LR, n = 21)。术前、术后和出院时(术后24小时)使用湿度计在颈部、胸区、三角区、肘窝和腕管处测量皮下液体水平。记录手术时间和灌洗液量的数据。在统计分析中,参数资料的比较采用重复测量方差分析和独立样本t检验,非参数资料的比较采用Friedman检验和Mann-Whitney U检验。结果:RCR和LR的平均手术时间分别为29.0±12.1 min和30.0±10.9 min,平均冲洗液用量分别为3.8±0.9 L和4.0±0.7 L (p < 0.05)。两组患者颈部及三角肌区皮下水肿均未见明显增加。出院时,肘窝皮下积液百分比增加(RCR p = 0.04;结论:关节镜下唇部修复后可发生胸皮下水肿,在肩袖和唇部修复中,即使没有长时间的手术或过多的冲洗液使用,也可观察到肘窝和腕管的液体水平升高。这些发现强调了肩关节镜术后对水肿的谨慎处理,特别是唇侧修复,特别要注意胸区、肘窝和腕管,以防止潜在的并发症。该登记处由美国国家医学图书馆(www.Clinicaltrials: gov)赞助;注册名称:关节镜肩关节术后水肿检查ID: NCT06014203。
{"title":"Subcutaneous Pectoral Edema After Arthroscopic Labral Repair Despite Normal Irrigation Fluid Usage and Surgery Duration.","authors":"İnci Hazal Ayas, Yağız Oğul Akcan, Miray Haspolat, Mehmet Ali Tokgöz, İlke Keser, Ulunay Kanatlı","doi":"10.1111/os.14324","DOIUrl":"10.1111/os.14324","url":null,"abstract":"<p><strong>Objectives: </strong>Edema after shoulder arthroscopic surgery poses concerns due to its potential complications such as compartment syndrome, nerve damage, and respiratory issues. This study aimed to investigate the acute accumulation of subcutaneous fluid after shoulder arthroscopy.</p><p><strong>Methods: </strong>A prospective cohort study, providing Level III evidence was conducted on 50 patients undergoing arthroscopic shoulder surgery under interscalene block anaesthesia from September to December 2023. The patients were divided into two groups: rotator cuff repair (RCR, n = 29) and labral repair for shoulder instability (LR, n = 21). Subcutaneous fluid levels were measured preoperatively, postoperatively, and at discharge (24 h postsurgery) using the MoistureMeterD Compact at the neck, pectoral region, deltoid area, cubital fossa, and carpal tunnel. Data on surgery duration and irrigation fluid volume were documented. In the statistical analysis, repeated measures ANOVA and the independent-samples t-test were applied to compare parametric data, while the Friedman test and Mann-Whitney U test were used for nonparametric data.</p><p><strong>Results: </strong>The average operation time was 29.0 ± 12.1 min for RCR and 30.0 ± 10.9 min for LR, with average irrigation fluid use of 3.8 ± 0.9 and 4.0 ± 0.7 L, respectively (both p > 0.05). There was no increase in subcutaneous edema in the neck and deltoid region in both groups. At discharge, the percentage of subcutaneous fluid increased in the cubital fossa (p = 0.04 for RCR; p < 0.001 for LR) and carpal tunnel (both p < 0.001) in oth groups, whereas pectoral edema increased only in the labral repair group (p = 0.04).</p><p><strong>Conclusions: </strong>Subcutaneous pectoral edema can occur following arthroscopic labral repair, and increased fluid levels in the cubital fossa and carpal tunnel were observed in both rotator cuff and labral repairs, even in the absence of prolonged surgery or excessive irrigation fluid use. These findings highlight the need for careful postoperative management of edema after shoulder arthroscopy, particularly for labral repairs, with special attention to the pectoral region, cubital fossa, and carpal tunnel to prevent potential complications. The registry is sponsored by the United States National Library of Medicine (www.</p><p><strong>Clinicaltrials: </strong>gov); Registry Name: Examination of Edema After Arthroscopic Shoulder Surgery ID: NCT06014203.</p>","PeriodicalId":19566,"journal":{"name":"Orthopaedic Surgery","volume":" ","pages":"624-630"},"PeriodicalIF":1.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11787983/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143009245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Jack Surgery: Reconstructing Collapsed Femoral Head in Association Research Circulation Osseous Stage III Osteonecrosis: A Series of 13 Cases. 杰克手术:重建塌陷股骨头的关联研究 循环骨性 III 期骨坏死:13例系列病例
IF 1.8 2区 医学 Q2 ORTHOPEDICS Pub Date : 2025-02-01 Epub Date: 2024-11-22 DOI: 10.1111/os.14298
Ying Zhong, Yichen Gong, Shuaijie Lv, Wenxi Du, Xun Liu, Jianhua Zhang, Peijian Tong

Objective: According to Association Research Circulation Osseous (ARCO) staging, patients with ARCO III osteonecrosis of femoral head (ONFH) have joint pain and dysfunction due to the collapse of femoral head. Current hip preservation surgeries are not satisfying in the treatment of ARCO III ONFH according to the long-term follow-up. In our practice, we focused on reconstructing femoral head by restoring the round shape of femoral head and subsequently preventing the development of hip arthritis. To lift the collapsed femoral head and postpone the potential total hip arthroplasty, we practiced Jack surgery, combining surgical hip dislocation, removal of necrotic bone, impaction bone grafting, and lifting the cartilage of femoral head.

Methods: From February 2019 to July 2022, 13 patients (15 hips) who received Jack surgery in the research center were included in this retrospective study. Follow-up was conducted every 3 months after surgery for imaging and clinical evaluation. The differences between visual analogue scale (VAS) and Harris hip score (HSS) before and after surgery were compared to observe whether the femoral head collapsed and whether osteotomy healed after surgery. Severe collapse of the femoral head ( > 2 mm) or receiving total hip arthroplasty (THA) was defined as failure of hip preservation therapy. An Independent sample t-test was used to compare the data, and the chi-square test was used for categorical data.

Results: All the 13 patients successfully completed the surgery and were followed up. The average time of follow-up was 36.46 ± 16.87 months (ranging from 14 to 66 months). HSS was assessed 12 months after surgery: excellent in 1 patient with 1 hip; good in 9 patients with 11 hips; modest in 3 patients with 3 hips. To the last follow-up, the VAS scores decreased from 6.17 ± 1.02 to 2.08 ± 0.90 (p < 0.001), HSS increased from 46.69 ± 4.15 to 89.77 ± 2.86 (p < 0.001). No deep infection, fracture, osteotomy nonunion, nerve injury, deep vein thrombosis, pulmonary embolism, or other complications occurred.

Conclusion: For young patients with ONFH of ACRO III, this surgical technique can effectively restore the original shape of the femoral head and achieve satisfactory hip function in the short term. The mechanism is similar to jacking the roof of a house; thus, we named it "Jack surgery".

目的:根据骨关节循环研究协会(ARCO)的分期,ARCO III 型股骨头坏死(ONFH)患者因股骨头塌陷而出现关节疼痛和功能障碍。根据长期随访,目前的保髋手术在治疗ARCO III型股骨头坏死方面并不令人满意。在我们的实践中,我们的重点是重建股骨头,恢复股骨头的圆形,进而预防髋关节炎的发生。为了抬高塌陷的股骨头,推迟潜在的全髋关节置换术,我们实施了Jack手术,将手术髋关节脱位、坏死骨清除、撞击植骨和抬高股骨头软骨结合起来:2019年2月至2022年7月,研究中心共纳入13例(15髋)接受Jack手术的患者进行回顾性研究。术后每3个月随访一次,进行影像学和临床评估。比较手术前后视觉模拟量表(VAS)和哈里斯髋关节评分(HSS)的差异,观察股骨头是否塌陷以及术后截骨是否愈合。股骨头严重塌陷(> 2 mm)或接受全髋关节置换术(THA)被定义为髋关节保护治疗失败。数据比较采用独立样本t检验,分类数据采用卡方检验:结果:所有13名患者都成功完成了手术并接受了随访。平均随访时间为 36.46 ± 16.87 个月(14 至 66 个月)。术后12个月的HSS评估结果为:1名患者的1个髋关节为 "优";9名患者的11个髋关节为 "良";3名患者的3个髋关节为 "中"。在最后一次随访中,VAS评分从6.17±1.02分降至2.08±0.90分(P,结论):对于患有 ACRO III 型 ONFH 的年轻患者,该手术方法可有效恢复股骨头的原始形状,并在短期内获得满意的髋关节功能。其原理类似于用千斤顶顶起房顶,因此我们将其命名为 "千斤顶手术"。
{"title":"Jack Surgery: Reconstructing Collapsed Femoral Head in Association Research Circulation Osseous Stage III Osteonecrosis: A Series of 13 Cases.","authors":"Ying Zhong, Yichen Gong, Shuaijie Lv, Wenxi Du, Xun Liu, Jianhua Zhang, Peijian Tong","doi":"10.1111/os.14298","DOIUrl":"10.1111/os.14298","url":null,"abstract":"<p><strong>Objective: </strong>According to Association Research Circulation Osseous (ARCO) staging, patients with ARCO III osteonecrosis of femoral head (ONFH) have joint pain and dysfunction due to the collapse of femoral head. Current hip preservation surgeries are not satisfying in the treatment of ARCO III ONFH according to the long-term follow-up. In our practice, we focused on reconstructing femoral head by restoring the round shape of femoral head and subsequently preventing the development of hip arthritis. To lift the collapsed femoral head and postpone the potential total hip arthroplasty, we practiced Jack surgery, combining surgical hip dislocation, removal of necrotic bone, impaction bone grafting, and lifting the cartilage of femoral head.</p><p><strong>Methods: </strong>From February 2019 to July 2022, 13 patients (15 hips) who received Jack surgery in the research center were included in this retrospective study. Follow-up was conducted every 3 months after surgery for imaging and clinical evaluation. The differences between visual analogue scale (VAS) and Harris hip score (HSS) before and after surgery were compared to observe whether the femoral head collapsed and whether osteotomy healed after surgery. Severe collapse of the femoral head ( > 2 mm) or receiving total hip arthroplasty (THA) was defined as failure of hip preservation therapy. An Independent sample t-test was used to compare the data, and the chi-square test was used for categorical data.</p><p><strong>Results: </strong>All the 13 patients successfully completed the surgery and were followed up. The average time of follow-up was 36.46 ± 16.87 months (ranging from 14 to 66 months). HSS was assessed 12 months after surgery: excellent in 1 patient with 1 hip; good in 9 patients with 11 hips; modest in 3 patients with 3 hips. To the last follow-up, the VAS scores decreased from 6.17 ± 1.02 to 2.08 ± 0.90 (p < 0.001), HSS increased from 46.69 ± 4.15 to 89.77 ± 2.86 (p < 0.001). No deep infection, fracture, osteotomy nonunion, nerve injury, deep vein thrombosis, pulmonary embolism, or other complications occurred.</p><p><strong>Conclusion: </strong>For young patients with ONFH of ACRO III, this surgical technique can effectively restore the original shape of the femoral head and achieve satisfactory hip function in the short term. The mechanism is similar to jacking the roof of a house; thus, we named it \"Jack surgery\".</p>","PeriodicalId":19566,"journal":{"name":"Orthopaedic Surgery","volume":" ","pages":"644-652"},"PeriodicalIF":1.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11787987/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142687947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Orthopaedic Surgery
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1