Pub Date : 2025-11-01Epub Date: 2025-10-11DOI: 10.1111/os.70186
Timo A Nees, Mustafa Hariri, Christian T Müller, Moritz M Innmann, David M Spranz, Fabian Westhauser, Tilman Walker, Tobias Reiner
Objectives: The treatment of extensive acetabular bone defects presents significant challenges in revision total hip arthroplasty (rTHA). Custom-made implants, tailored to patient-specific anatomy via 3D printing, offer potential advantages regarding implant stability and alignment. Precise positioning of these large-volume implants is crucial for primary stability and long-term fixation, but can be surgically demanding, especially when intramedullary iliac press-fit stems are used. In contrast to triflange custom-made implants, data on the implantation accuracy of custom-made acetabular components with iliac stem fixation remain limited. This study aimed to assess the accuracy of implant positioning by comparing preoperatively planned component positions with postoperative radiographic outcomes, focusing on anteversion (AV), inclination (INCL), and the center of rotation (CoR).
Methods: In this retrospective cohort study, 24 patients with large acetabular defects (Paprosky ≥ 3A) underwent rTHA with custom-made acetabular components with intramedullary press-fit iliac stem fixation between November 2022 and April 2024. Implantation accuracy was evaluated by comparing the planned positions on preoperative CT scans with the actual implant positions observed on 6-week postoperative radiographs using a previously validated methodology. Discrepancies in AV, INCL, and the CoR were analyzed.
Results: A high degree of alignment with preoperative plans was observed. The mean postoperative AV was 9.96° ± 6.4° (planned: 10.2°), and the mean INCL was 46.3° ± 3.2° (planned: 44.6°). The deviations were minor (Δ AV: -0.25°, Δ INCL: 1.7°), confirming the precision of implant placement. Four implants had CoR deviations exceeding 5 mm cranially (mean cranial shift: 1.77 ± 3.97 mm), and five exceeded 5 mm laterally. Most deviations were within clinically acceptable ranges.
Conclusions: Our findings demonstrate that custom-made acetabular components with iliac stem fixation can be implanted with high accuracy. Moreover, our results support the use of standard radiographs for the postoperative assessment of implant positioning precision. This study provides valuable insights into the accuracy of implant placement in complex rTHA cases, highlighting the role of patient-specific implant technologies in enhancing surgical outcomes.
{"title":"Implantation Accuracy of Custom-Made Acetabular Components With Iliac Stem Fixation for Large Bone Defects in Hip Revision Surgery.","authors":"Timo A Nees, Mustafa Hariri, Christian T Müller, Moritz M Innmann, David M Spranz, Fabian Westhauser, Tilman Walker, Tobias Reiner","doi":"10.1111/os.70186","DOIUrl":"10.1111/os.70186","url":null,"abstract":"<p><strong>Objectives: </strong>The treatment of extensive acetabular bone defects presents significant challenges in revision total hip arthroplasty (rTHA). Custom-made implants, tailored to patient-specific anatomy via 3D printing, offer potential advantages regarding implant stability and alignment. Precise positioning of these large-volume implants is crucial for primary stability and long-term fixation, but can be surgically demanding, especially when intramedullary iliac press-fit stems are used. In contrast to triflange custom-made implants, data on the implantation accuracy of custom-made acetabular components with iliac stem fixation remain limited. This study aimed to assess the accuracy of implant positioning by comparing preoperatively planned component positions with postoperative radiographic outcomes, focusing on anteversion (AV), inclination (INCL), and the center of rotation (CoR).</p><p><strong>Methods: </strong>In this retrospective cohort study, 24 patients with large acetabular defects (Paprosky ≥ 3A) underwent rTHA with custom-made acetabular components with intramedullary press-fit iliac stem fixation between November 2022 and April 2024. Implantation accuracy was evaluated by comparing the planned positions on preoperative CT scans with the actual implant positions observed on 6-week postoperative radiographs using a previously validated methodology. Discrepancies in AV, INCL, and the CoR were analyzed.</p><p><strong>Results: </strong>A high degree of alignment with preoperative plans was observed. The mean postoperative AV was 9.96° ± 6.4° (planned: 10.2°), and the mean INCL was 46.3° ± 3.2° (planned: 44.6°). The deviations were minor (Δ AV: -0.25°, Δ INCL: 1.7°), confirming the precision of implant placement. Four implants had CoR deviations exceeding 5 mm cranially (mean cranial shift: 1.77 ± 3.97 mm), and five exceeded 5 mm laterally. Most deviations were within clinically acceptable ranges.</p><p><strong>Conclusions: </strong>Our findings demonstrate that custom-made acetabular components with iliac stem fixation can be implanted with high accuracy. Moreover, our results support the use of standard radiographs for the postoperative assessment of implant positioning precision. This study provides valuable insights into the accuracy of implant placement in complex rTHA cases, highlighting the role of patient-specific implant technologies in enhancing surgical outcomes.</p>","PeriodicalId":19566,"journal":{"name":"Orthopaedic Surgery","volume":" ","pages":"3159-3168"},"PeriodicalIF":2.1,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12580221/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145275374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: In spinal surgery, precise identification of high-speed bur milling states is crucial for patient safety. This study investigates whether integrating tactile and auditory perception can enhance the accuracy of milling state detection in robot-assisted cervical laminectomy.
Methods: Based on the mathematical and physical model of vibration and sound in high-speed bur milling bone, the feasibility of employing vibration and sound characteristics to identify the milling states of high-speed bur is studied systematically. Cervical laminectomy was performed on the cervical spine of the sheep. During the signal acquisition process, acceleration sensors and microphones were installed to collect vibration and sound signals, respectively. Seven milling states were set up in the experiment: (1) Milling depths of cortical bone (CTB): 0.5, 1.0, and 1.5 mm; (2) Milling depths of milling of cancellous bone (CCB): 0.5, 1.0, and 1.5 mm; (3) Boundary conditions: high-speed bur idling or complete penetration of bone (PT). The milling speed was set at 0.5 mm/s, the milling angle was 45°, and the bur diameter was 4 mm. The vibration or sound was extracted by Fast Fourier Transform (FFT) in the frequency domain of the first nine harmonics to generate the feature vector in 9 dimensions (9-D) space. These vibration and sound features were combined to form an 18-D multi-perception spatial vector for subsequent analysis, including five machine learning algorithms: Support Vector Machine (SVM), K Nearest Neighbors (KNN), Naive Bayes (NB), Linear Discriminant Analysis (LDA), and Decision Tree (DT), and deep learning models: Long Short-Term Memory networks (LSTM).
Results: Based on the 18-D features of tactile and auditory multisensory fusion, the LSTM model is trained using 6600 sets of high-speed bur milling data. In order to achieve the best performance, a layer-by-layer parameter optimization strategy was used to determine the optimal parameter configuration, and finally, a single-layer LSTM with 12 memory units was constructed. In terms of accuracy and stability, the model is significantly superior to the machine learning algorithms (SVM, KNN, NB, LDA, and DT), and the accuracy of LSTM is 99.32% in the milling states identification of cervical lamina milling with high-speed bur.
Conclusion: Through theoretical analysis and experimental verification, the study built a multi-perception fusion framework based on tactile and auditory perception and accurately identified the cervical vertebra milling states through the LSTM model, which can provide perception means for operational spinal surgery robots in the future.
{"title":"Multisensory Integration for Identifying the Milling States in Robot-Assisted Cervical Laminectomy.","authors":"Chao Sun, Yingjie Zheng, Junfei Hu, Weixiang Ke, Fei Zhao, Guangming Xia, Yu Dai, Yuan Xue, Rui Wang","doi":"10.1111/os.70182","DOIUrl":"10.1111/os.70182","url":null,"abstract":"<p><strong>Objective: </strong>In spinal surgery, precise identification of high-speed bur milling states is crucial for patient safety. This study investigates whether integrating tactile and auditory perception can enhance the accuracy of milling state detection in robot-assisted cervical laminectomy.</p><p><strong>Methods: </strong>Based on the mathematical and physical model of vibration and sound in high-speed bur milling bone, the feasibility of employing vibration and sound characteristics to identify the milling states of high-speed bur is studied systematically. Cervical laminectomy was performed on the cervical spine of the sheep. During the signal acquisition process, acceleration sensors and microphones were installed to collect vibration and sound signals, respectively. Seven milling states were set up in the experiment: (1) Milling depths of cortical bone (CTB): 0.5, 1.0, and 1.5 mm; (2) Milling depths of milling of cancellous bone (CCB): 0.5, 1.0, and 1.5 mm; (3) Boundary conditions: high-speed bur idling or complete penetration of bone (PT). The milling speed was set at 0.5 mm/s, the milling angle was 45°, and the bur diameter was 4 mm. The vibration or sound was extracted by Fast Fourier Transform (FFT) in the frequency domain of the first nine harmonics to generate the feature vector in 9 dimensions (9-D) space. These vibration and sound features were combined to form an 18-D multi-perception spatial vector for subsequent analysis, including five machine learning algorithms: Support Vector Machine (SVM), K Nearest Neighbors (KNN), Naive Bayes (NB), Linear Discriminant Analysis (LDA), and Decision Tree (DT), and deep learning models: Long Short-Term Memory networks (LSTM).</p><p><strong>Results: </strong>Based on the 18-D features of tactile and auditory multisensory fusion, the LSTM model is trained using 6600 sets of high-speed bur milling data. In order to achieve the best performance, a layer-by-layer parameter optimization strategy was used to determine the optimal parameter configuration, and finally, a single-layer LSTM with 12 memory units was constructed. In terms of accuracy and stability, the model is significantly superior to the machine learning algorithms (SVM, KNN, NB, LDA, and DT), and the accuracy of LSTM is 99.32% in the milling states identification of cervical lamina milling with high-speed bur.</p><p><strong>Conclusion: </strong>Through theoretical analysis and experimental verification, the study built a multi-perception fusion framework based on tactile and auditory perception and accurately identified the cervical vertebra milling states through the LSTM model, which can provide perception means for operational spinal surgery robots in the future.</p>","PeriodicalId":19566,"journal":{"name":"Orthopaedic Surgery","volume":" ","pages":"3252-3261"},"PeriodicalIF":2.1,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12580257/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145258578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-01Epub Date: 2025-08-26DOI: 10.1111/os.70161
Chenchang He, Qiyao Li, Rui Huang, Xiang Gao, Li Li, Pei Fan
Pain is the main symptom of knee osteoarthritis (KOA) and the main cause for patients to seek medical treatment. Despite the development of various therapies to address pain, its efficacy often remains uncertain. According to the new classification of the International Association for the Study of Pain, pain is classified as nociceptive pain, neuropathic pain and nociplastic pain. This review sought to outline potential mechanisms and clinical manifestations within this new classification framework and provided tailored treatment recommendations for each type of pain. Moreover, we further divided nociceptive pain into three subgroups including Inflammatory Pain, Mechanical Pain, and BMLs-related Pain. We suggest: (1) For inflammatory pain, the use of anti-inflammatory medications such as NSAIDs and corticosteroids is recommended. (2) For mechanical pain, weight loss, adjustments to mechanical alignment of the lower limb, and rehabilitation training may significantly alleviate symptoms. (3) For BMLs-related pain, patients might benefit from treatment, such as reducing weight-bearing and implementing antiosteoporosis drugs. (4) For neuropathic pain, management may involve tricyclic antidepressants or anticonvulsants. (5) For nociplastic pain, we give priority to nonpharmacological therapies, with an emphasis on the biopsychosocial model, and encourage patients to adopt positive lifestyle changes, including physical activity, weight management, sleep hygiene, and self-management, as well as involvement in psychotherapy and intervention. In clinical practice, it is essential to recognize that many patients may present with a combination of these pain types. Thus, it becomes imperative to identify the primary pain type and craft precise and individual treatment strategies tailored to their specific needs.
疼痛是膝关节骨性关节炎(KOA)的主要症状,也是患者就医的主要原因。尽管发展了各种治疗方法来解决疼痛,但其疗效往往仍然不确定。根据国际疼痛研究协会(International Association for the Study of Pain)的新分类,疼痛分为伤害性疼痛、神经性疼痛和伤害性疼痛。这篇综述试图在这个新的分类框架内概述潜在的机制和临床表现,并为每种类型的疼痛提供量身定制的治疗建议。此外,我们进一步将伤害性疼痛分为三个亚组,包括炎症性疼痛、机械性疼痛和脑脊髓炎相关疼痛。我们建议:(1)对于炎症性疼痛,建议使用非甾体抗炎药和皮质类固醇等抗炎药物。(2)对于机械性疼痛,减轻体重、调整下肢机械对中、康复训练可显著缓解症状。(3)对于脑转移相关疼痛,患者可以通过减轻负重和服用抗骨质疏松药物等治疗获益。(4)对于神经性疼痛,可使用三环类抗抑郁药或抗惊厥药。(5)对于伤害性疼痛,我们优先考虑非药物治疗,强调生物心理社会模式,并鼓励患者采取积极的生活方式改变,包括身体活动,体重管理,睡眠卫生和自我管理,以及参与心理治疗和干预。在临床实践中,重要的是要认识到许多患者可能会出现这些疼痛类型的组合。因此,必须确定主要疼痛类型,并根据他们的具体需求制定精确和个性化的治疗策略。
{"title":"Pain Phenotype in Knee Osteoarthritis: Implications for Mechanism-Based Therapy.","authors":"Chenchang He, Qiyao Li, Rui Huang, Xiang Gao, Li Li, Pei Fan","doi":"10.1111/os.70161","DOIUrl":"10.1111/os.70161","url":null,"abstract":"<p><p>Pain is the main symptom of knee osteoarthritis (KOA) and the main cause for patients to seek medical treatment. Despite the development of various therapies to address pain, its efficacy often remains uncertain. According to the new classification of the International Association for the Study of Pain, pain is classified as nociceptive pain, neuropathic pain and nociplastic pain. This review sought to outline potential mechanisms and clinical manifestations within this new classification framework and provided tailored treatment recommendations for each type of pain. Moreover, we further divided nociceptive pain into three subgroups including Inflammatory Pain, Mechanical Pain, and BMLs-related Pain. We suggest: (1) For inflammatory pain, the use of anti-inflammatory medications such as NSAIDs and corticosteroids is recommended. (2) For mechanical pain, weight loss, adjustments to mechanical alignment of the lower limb, and rehabilitation training may significantly alleviate symptoms. (3) For BMLs-related pain, patients might benefit from treatment, such as reducing weight-bearing and implementing antiosteoporosis drugs. (4) For neuropathic pain, management may involve tricyclic antidepressants or anticonvulsants. (5) For nociplastic pain, we give priority to nonpharmacological therapies, with an emphasis on the biopsychosocial model, and encourage patients to adopt positive lifestyle changes, including physical activity, weight management, sleep hygiene, and self-management, as well as involvement in psychotherapy and intervention. In clinical practice, it is essential to recognize that many patients may present with a combination of these pain types. Thus, it becomes imperative to identify the primary pain type and craft precise and individual treatment strategies tailored to their specific needs.</p>","PeriodicalId":19566,"journal":{"name":"Orthopaedic Surgery","volume":" ","pages":"3007-3021"},"PeriodicalIF":2.1,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12580230/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144963770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-01Epub Date: 2025-09-04DOI: 10.1111/os.70166
Lin Zhao, Zhengxuan Peng, Lei Cao, Mingdong Lu, Zhanxiang Wu, Ning Ding, Sheng Zhou, Jie Liu
Background: Lumbar spondylolisthesis (LS) is a spinal disorder that often necessitates surgical intervention. However, evidence on the comparative clinical value of robot-assisted full-endoscopic transforaminal lumbar interbody fusion (RA FE-TLIF) versus conventional FE-TLIF in early-grade (Grades I and II) LS remains limited, leaving uncertainty about its true clinical value in this patient population. This study aims to compare the clinical efficacy and safety of FE-TLIF with RA FE-TLIF in patients with Grade I and II LS.
Methods: A retrospective analysis was conducted on 47 patients who underwent surgical treatment for LS between April 2022 and April 2023 at our hospital. Patients were divided into two groups: 22 underwent RA FE-TLIF, and 25 underwent FE-TLIF. Key outcomes measured included operative time, intraoperative blood loss, postoperative recovery time, fusion rate, screw placement accuracy, Visual Analogue Scale (VAS), the Japanese Orthopaedic Association (JOA) scores, and the incidence of postoperative complications. Statistical analyses were performed using the independent-sample t test for continuous variables and the chi-square test for categorical variables, with a significance threshold of p < 0.05.
Results: The RA FE-TLIF group exhibited significantly shorter operative times and lower intraoperative blood loss compared to the FE-TLIF group (p < 0.05). Postoperative recovery, as measured by hospital stay, was also shorter in the RA FE-TLIF group (p = 0.001). VAS and JOA scores indicated greater pain relief and functional improvement in the RA FE-TLIF group, with statistically significant differences observed at both 1 month and final follow-up (p < 0.05). The incidence of postoperative complications was lower in the RA FE-TLIF group, though this difference was not statistically significant (p = 0.144). Complete fusion rates were 95.45% in the RA FE-TLIF group and 88.00% in the FE-TLIF group, with no significant difference (p > 0.05). Screw placement accuracy was higher in the RA FE-TLIF group (97.73%) than in the FE-TLIF group (89.00%), with a significant difference (p < 0.05).
Conclusion: RA FE-TLIF demonstrates superior clinical outcomes compared to FE-TLIF in the treatment of LS. These findings support the broader adoption of RA FE-TLIF as a preferred surgical technique for this condition.
{"title":"Clinical Outcomes of RA FE-TLIF Compared to FE-TLIF in Patients With Lumbar Spondylolisthesis: A Retrospective Study.","authors":"Lin Zhao, Zhengxuan Peng, Lei Cao, Mingdong Lu, Zhanxiang Wu, Ning Ding, Sheng Zhou, Jie Liu","doi":"10.1111/os.70166","DOIUrl":"10.1111/os.70166","url":null,"abstract":"<p><strong>Background: </strong>Lumbar spondylolisthesis (LS) is a spinal disorder that often necessitates surgical intervention. However, evidence on the comparative clinical value of robot-assisted full-endoscopic transforaminal lumbar interbody fusion (RA FE-TLIF) versus conventional FE-TLIF in early-grade (Grades I and II) LS remains limited, leaving uncertainty about its true clinical value in this patient population. This study aims to compare the clinical efficacy and safety of FE-TLIF with RA FE-TLIF in patients with Grade I and II LS.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on 47 patients who underwent surgical treatment for LS between April 2022 and April 2023 at our hospital. Patients were divided into two groups: 22 underwent RA FE-TLIF, and 25 underwent FE-TLIF. Key outcomes measured included operative time, intraoperative blood loss, postoperative recovery time, fusion rate, screw placement accuracy, Visual Analogue Scale (VAS), the Japanese Orthopaedic Association (JOA) scores, and the incidence of postoperative complications. Statistical analyses were performed using the independent-sample t test for continuous variables and the chi-square test for categorical variables, with a significance threshold of p < 0.05.</p><p><strong>Results: </strong>The RA FE-TLIF group exhibited significantly shorter operative times and lower intraoperative blood loss compared to the FE-TLIF group (p < 0.05). Postoperative recovery, as measured by hospital stay, was also shorter in the RA FE-TLIF group (p = 0.001). VAS and JOA scores indicated greater pain relief and functional improvement in the RA FE-TLIF group, with statistically significant differences observed at both 1 month and final follow-up (p < 0.05). The incidence of postoperative complications was lower in the RA FE-TLIF group, though this difference was not statistically significant (p = 0.144). Complete fusion rates were 95.45% in the RA FE-TLIF group and 88.00% in the FE-TLIF group, with no significant difference (p > 0.05). Screw placement accuracy was higher in the RA FE-TLIF group (97.73%) than in the FE-TLIF group (89.00%), with a significant difference (p < 0.05).</p><p><strong>Conclusion: </strong>RA FE-TLIF demonstrates superior clinical outcomes compared to FE-TLIF in the treatment of LS. These findings support the broader adoption of RA FE-TLIF as a preferred surgical technique for this condition.</p>","PeriodicalId":19566,"journal":{"name":"Orthopaedic Surgery","volume":" ","pages":"3201-3210"},"PeriodicalIF":2.1,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12580220/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145001012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-01Epub Date: 2025-09-18DOI: 10.1111/os.70176
Xue-Peng Wei, Hung-Lun Hsieh, Qing-De Wang, Yi-Hsun Huang, Erh-Ti Ernest Lin, Chen-Wei Yeh, Yuan-Shun Lo
Objective: Adult thoracolumbar kyphosis secondary to osteoporotic vertebral fractures (OVF) impairs the quality of life. Traditional 3CO provides correction but carries a high risk of complications, especially in the elderly. Minimally invasive anterior approaches may be safer. This study aims to compare the radiographic and clinical outcomes of septuagenarians with thoracolumbar kyphosis treated with single-position navigated lateral column realignment with anterior longitudinal ligament release (LCR-A) plus posterior column osteotomy (PCO) and posterior spinal fusion (PSF), or percutaneous pedicle screws (PPS) versus three-column osteotomy (3CO).
Materials and methods: This retrospective study included 21 patients with LCR-A and 54 with 3CO prospectively treated between March 2020 and April 2024. Radiographic parameters, the Oswestry Disability Index (ODI), SRS-22 scores, complications, and perioperative data were analyzed over a 2-year follow-up period.
Results: Although LCR-A patients were older, they had significantly reduced blood loss, shorter operative times, and fewer fused levels than 3CO patients. LCR-A achieved comparable deformity correction, with fewer complications, lower postoperative ODI, and better SRS-22 scores. The LCR-A group maintained radiographic correction, with fewer new neurological deficits and lower rates of infection, ileus, and delirium.
Conclusions: Single-position navigated LCR-A is a safer and less invasive alternative to 3CO in elderly patients with thoracolumbar kyphosis, offering effective deformity correction, fewer complications, improved functional outcomes, and enhanced recovery.
{"title":"Lateral Column Realignment Combined With Anterior Longitudinal Ligament Release Versus Three-Column Osteotomy in the Treatment of Thoracolumbar Kyphosis in Septuagenarians: A Retrospective Comparative Cohort Study.","authors":"Xue-Peng Wei, Hung-Lun Hsieh, Qing-De Wang, Yi-Hsun Huang, Erh-Ti Ernest Lin, Chen-Wei Yeh, Yuan-Shun Lo","doi":"10.1111/os.70176","DOIUrl":"10.1111/os.70176","url":null,"abstract":"<p><strong>Objective: </strong>Adult thoracolumbar kyphosis secondary to osteoporotic vertebral fractures (OVF) impairs the quality of life. Traditional 3CO provides correction but carries a high risk of complications, especially in the elderly. Minimally invasive anterior approaches may be safer. This study aims to compare the radiographic and clinical outcomes of septuagenarians with thoracolumbar kyphosis treated with single-position navigated lateral column realignment with anterior longitudinal ligament release (LCR-A) plus posterior column osteotomy (PCO) and posterior spinal fusion (PSF), or percutaneous pedicle screws (PPS) versus three-column osteotomy (3CO).</p><p><strong>Materials and methods: </strong>This retrospective study included 21 patients with LCR-A and 54 with 3CO prospectively treated between March 2020 and April 2024. Radiographic parameters, the Oswestry Disability Index (ODI), SRS-22 scores, complications, and perioperative data were analyzed over a 2-year follow-up period.</p><p><strong>Results: </strong>Although LCR-A patients were older, they had significantly reduced blood loss, shorter operative times, and fewer fused levels than 3CO patients. LCR-A achieved comparable deformity correction, with fewer complications, lower postoperative ODI, and better SRS-22 scores. The LCR-A group maintained radiographic correction, with fewer new neurological deficits and lower rates of infection, ileus, and delirium.</p><p><strong>Conclusions: </strong>Single-position navigated LCR-A is a safer and less invasive alternative to 3CO in elderly patients with thoracolumbar kyphosis, offering effective deformity correction, fewer complications, improved functional outcomes, and enhanced recovery.</p><p><strong>Level of evidence: </strong>IV.</p>","PeriodicalId":19566,"journal":{"name":"Orthopaedic Surgery","volume":" ","pages":"3241-3251"},"PeriodicalIF":2.1,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12580243/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145086588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-01Epub Date: 2025-09-19DOI: 10.1111/os.70118
Haohao Bai, Yadi Sun, Jianxiong Ma, Ying Wang, Yan Wang, Bin Lu, Lei Sun, Hongzhen Jin, Xingwen Zhao, Xinlong Ma
Objective: Knee osteoarthritis (KOA) is a prevalent condition characterized by cartilage degeneration, tissue destruction, and bone hyperplasia, with pain being the primary symptom. High tibial osteotomy (HTO) has emerged as an effective treatment for symptomatic unicompartmental KOA, focusing on realigning force vectors to redistribute mechanical stress and alleviate pain. This study aims to address the question of whether two-dimensional (2D) and three-dimensional (3D) preoperative planning methods yield different correction angles and distraction distances in open-wedge high tibial osteotomy (OWHTO). By comparing these methodologies, we seek to evaluate their impact on surgical outcomes and patient prognosis.
Methods: A retrospective analysis was conducted involving patients diagnosed with unicompartmental medial knee osteoarthritis (KOA) who exhibited deviations in the mechanical axis of the lower limbs. These patients underwent OWHTO between January 2021 and August 2022. Both 3D and 2D preoperative planning procedures for OWHTO were employed, targeting an ideal alignment with the weight-bearing line (%WBL) set at 62.5%. The study quantitatively assessed the differences in correction angles and distraction distances associated with the two surgical planning methods using paired t-tests and non-parametric Wilcoxon signed-rank tests.
Results: The study comprised a total of 102 patients. It was observed that the mean correction angle in the 2D approach was significantly greater than that recorded in the 3D approach (p < 0.001), with an average difference of 1.49° ± 1.70°. The medial opening gap differences for OWHTO between the two approaches measured 2.1 ± 2.06 mm.
Conclusions: To summarize, the 2D preoperative planning method for OWHTO necessitates a larger correction angle and a wider medial opening gap relative to the 3D planning approach when aiming for the same WBL. Therefore, it is crucial for surgeons to take into account the variances between 2D and 3D planning and to evaluate potential correction errors during the surgical procedure while strategizing for OWHTO.
{"title":"Comparison of Two-Dimensional and Three-Dimensional Preoperative Planning Measurements for High Tibial Osteotomy.","authors":"Haohao Bai, Yadi Sun, Jianxiong Ma, Ying Wang, Yan Wang, Bin Lu, Lei Sun, Hongzhen Jin, Xingwen Zhao, Xinlong Ma","doi":"10.1111/os.70118","DOIUrl":"10.1111/os.70118","url":null,"abstract":"<p><strong>Objective: </strong>Knee osteoarthritis (KOA) is a prevalent condition characterized by cartilage degeneration, tissue destruction, and bone hyperplasia, with pain being the primary symptom. High tibial osteotomy (HTO) has emerged as an effective treatment for symptomatic unicompartmental KOA, focusing on realigning force vectors to redistribute mechanical stress and alleviate pain. This study aims to address the question of whether two-dimensional (2D) and three-dimensional (3D) preoperative planning methods yield different correction angles and distraction distances in open-wedge high tibial osteotomy (OWHTO). By comparing these methodologies, we seek to evaluate their impact on surgical outcomes and patient prognosis.</p><p><strong>Methods: </strong>A retrospective analysis was conducted involving patients diagnosed with unicompartmental medial knee osteoarthritis (KOA) who exhibited deviations in the mechanical axis of the lower limbs. These patients underwent OWHTO between January 2021 and August 2022. Both 3D and 2D preoperative planning procedures for OWHTO were employed, targeting an ideal alignment with the weight-bearing line (%WBL) set at 62.5%. The study quantitatively assessed the differences in correction angles and distraction distances associated with the two surgical planning methods using paired t-tests and non-parametric Wilcoxon signed-rank tests.</p><p><strong>Results: </strong>The study comprised a total of 102 patients. It was observed that the mean correction angle in the 2D approach was significantly greater than that recorded in the 3D approach (p < 0.001), with an average difference of 1.49° ± 1.70°. The medial opening gap differences for OWHTO between the two approaches measured 2.1 ± 2.06 mm.</p><p><strong>Conclusions: </strong>To summarize, the 2D preoperative planning method for OWHTO necessitates a larger correction angle and a wider medial opening gap relative to the 3D planning approach when aiming for the same WBL. Therefore, it is crucial for surgeons to take into account the variances between 2D and 3D planning and to evaluate potential correction errors during the surgical procedure while strategizing for OWHTO.</p>","PeriodicalId":19566,"journal":{"name":"Orthopaedic Surgery","volume":" ","pages":"3169-3177"},"PeriodicalIF":2.1,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12580252/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145086604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-01Epub Date: 2025-09-04DOI: 10.1111/os.70167
Chao Fan Chen, Ling Yao Kong, Tao Li, Lei Yao, Yang Xu, Li Wang, Hong Yu Zhou, Jian Li
To manage anterior cruciate ligament (ACL) injury, both remnant-preserving anterior cruciate ligament reconstruction (ACLR) and standard ACLR without remnant preservation are applied. This study aims to systematically evaluate clinical outcomes of remnant-preserving versus standard ACLR techniques by analyzing randomized controlled trials (RCTs). The PubMed, Embase, and Cochrane Library databases were used to identify studies published from January 2000 to November 2024. Based on the PICOS framework, we systematically reviewed RCTs in which patients with ACL injuries compared ACLR with remnant preservation versus standard ACLR in terms of International Knee Documentation Committee (IKDC) score, Lysholm score, Lachman test, pivot shift test, KT1000/2000 arthrometer side-to-side difference (SSD), synovial coverage, proprioception evaluation, cyclops lesion, and range of motion (ROM). Data were pooled using the random-effects model or fixed-effects model, based on the heterogeneity. The quality of the included literature was assessed based on the Cochrane Risk of Bias tool (ROB 2.0), and the GRADE criteria were applied to rate evidence quality for key outcomes. Review Manager 5.4 and Stata 15 were used for the statistical analyses. The relative risk (RR) was used for dichotomous data, and the mean difference (MD) was used for continuous variable data. Both types of indicators were expressed as 95% confidence intervals (CIs). The minimal clinically important difference (MCID) was adopted to determine whether patients improved enough clinically to notice a difference. Subgroup analyses were conducted for outcomes failing to reach MCID thresholds in order to examine potential modifiers of different follow-up durations and remnant preservation techniques. A total of 10 studies were included in the qualitative review and meta-analysis. Although there were statistically significant differences between the remnant preservation group and the standard technique group in favor of the remnant preservation technique with respect to postoperative Lysholm score (MD 1.44; 95% CI, 0.60-2.29; I 2 = 23%; p < 0.01) (GRADE: Moderate), SSD (MD -0.57; 95% CI, -0.98 to -0.15; I 2 = 86%; p < 0.01) (GRADE: Low) and proprioception recovery (MD -0.57; 95% CI, -0.83 to -0.31; I 2 = 0%; p < 0.01) (GRADE: Low), these observed differences are so small that they are unlikely to be clinically relevant. No differences were found in other clinical outcomes between the two groups. The follow-up duration and remnant preservation techniques were not identified as the key factors influencing the differences between remnant preservation ACLR and standard ACLR. No clinically meaningful benefit in postoperative knee stability or function; remnant preservation may be considered primarily when technical feasibility is high and remnant quality is optimal. This is achieved without increasing the risk of cyclops lesions and deficiency of ROM.
为了治疗前交叉韧带(ACL)损伤,采用保留残体的前交叉韧带重建(ACLR)和不保留残体的标准前交叉韧带重建(ACLR)。本研究旨在通过分析随机对照试验(rct),系统地评估残体保存与标准ACLR技术的临床结果。PubMed、Embase和Cochrane图书馆数据库被用于识别2000年1月至2024年11月发表的研究。基于PICOS框架,我们系统地回顾了ACL损伤患者在国际膝关节文献委员会(IKDC)评分、Lysholm评分、Lachman测试、枢轴移位测试、KT1000/2000关节计侧差(SSD)、滑膜覆盖、本体感觉评估、独眼病变和活动范围(ROM)方面比较残肢保留ACLR与标准ACLR的随机对照试验。根据异质性,采用随机效应模型或固定效应模型对数据进行汇总。采用Cochrane风险偏倚工具(ROB 2.0)评估纳入文献的质量,并采用GRADE标准评价关键结局的证据质量。使用Review Manager 5.4和Stata 15进行统计分析。二分类资料采用相对危险度(RR),连续变量资料采用平均差值(MD)。两类指标均以95%置信区间(ci)表示。采用最小临床重要差异(MCID)来确定患者是否在临床上改善到足以注意到差异。对未达到MCID阈值的结果进行亚组分析,以检查不同随访时间和残余保存技术的潜在改变因素。共纳入10项研究进行定性回顾和荟萃分析。尽管残体保存组与标准技术组在术后Lysholm评分方面存在统计学差异(MD 1.44; 95% CI, 0.60-2.29; I2 = 23%; p 2 = 86%; p 2 = 0%; p
{"title":"Remnant Preservation in Anterior Cruciate Ligament Reconstruction Versus Non-Preservation Methods: A Systematic Review and Meta-Analysis.","authors":"Chao Fan Chen, Ling Yao Kong, Tao Li, Lei Yao, Yang Xu, Li Wang, Hong Yu Zhou, Jian Li","doi":"10.1111/os.70167","DOIUrl":"10.1111/os.70167","url":null,"abstract":"<p><p>To manage anterior cruciate ligament (ACL) injury, both remnant-preserving anterior cruciate ligament reconstruction (ACLR) and standard ACLR without remnant preservation are applied. This study aims to systematically evaluate clinical outcomes of remnant-preserving versus standard ACLR techniques by analyzing randomized controlled trials (RCTs). The PubMed, Embase, and Cochrane Library databases were used to identify studies published from January 2000 to November 2024. Based on the PICOS framework, we systematically reviewed RCTs in which patients with ACL injuries compared ACLR with remnant preservation versus standard ACLR in terms of International Knee Documentation Committee (IKDC) score, Lysholm score, Lachman test, pivot shift test, KT1000/2000 arthrometer side-to-side difference (SSD), synovial coverage, proprioception evaluation, cyclops lesion, and range of motion (ROM). Data were pooled using the random-effects model or fixed-effects model, based on the heterogeneity. The quality of the included literature was assessed based on the Cochrane Risk of Bias tool (ROB 2.0), and the GRADE criteria were applied to rate evidence quality for key outcomes. Review Manager 5.4 and Stata 15 were used for the statistical analyses. The relative risk (RR) was used for dichotomous data, and the mean difference (MD) was used for continuous variable data. Both types of indicators were expressed as 95% confidence intervals (CIs). The minimal clinically important difference (MCID) was adopted to determine whether patients improved enough clinically to notice a difference. Subgroup analyses were conducted for outcomes failing to reach MCID thresholds in order to examine potential modifiers of different follow-up durations and remnant preservation techniques. A total of 10 studies were included in the qualitative review and meta-analysis. Although there were statistically significant differences between the remnant preservation group and the standard technique group in favor of the remnant preservation technique with respect to postoperative Lysholm score (MD 1.44; 95% CI, 0.60-2.29; I <sup>2</sup> = 23%; p < 0.01) (GRADE: Moderate), SSD (MD -0.57; 95% CI, -0.98 to -0.15; I <sup>2</sup> = 86%; p < 0.01) (GRADE: Low) and proprioception recovery (MD -0.57; 95% CI, -0.83 to -0.31; I <sup>2</sup> = 0%; p < 0.01) (GRADE: Low), these observed differences are so small that they are unlikely to be clinically relevant. No differences were found in other clinical outcomes between the two groups. The follow-up duration and remnant preservation techniques were not identified as the key factors influencing the differences between remnant preservation ACLR and standard ACLR. No clinically meaningful benefit in postoperative knee stability or function; remnant preservation may be considered primarily when technical feasibility is high and remnant quality is optimal. This is achieved without increasing the risk of cyclops lesions and deficiency of ROM.</p>","PeriodicalId":19566,"journal":{"name":"Orthopaedic Surgery","volume":" ","pages":"3022-3035"},"PeriodicalIF":2.1,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12580229/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144992953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-01Epub Date: 2025-08-21DOI: 10.1111/os.70159
Linyun Tan, Ye Li, Xin Hu, Yitian Wang, Xiaolu Zhang, Xiaoyan Liu, Yi Luo, Yong Zhou, Chongqi Tu, Xiao Yang, Li Min
<p><strong>Objectives: </strong>Pelvic reconstruction with conventional 3D-printed prostheses faces a critical trade-off, where achieving sufficient porosity for optimal bone ingrowth often compromises essential mechanical stability. To address this challenge, this study evaluates the clinical outcomes of 3D-printed hemipelvic prostheses incorporating re-entrant chiral structure (RCS), a novel negative Poisson's ratio design, in patients undergoing pelvic reconstruction following tumor resection.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on 15 patients (eight females and seven males; mean age: 39.3 ± 11.7 years) with pelvic malignancies who underwent reconstruction using 3D-printed hemipelvic prostheses incorporating RCS between March 2018 and June 2023. The diagnoses included osteosarcoma (n = 8), Ewing's sarcoma (n = 3), chondrosarcoma (n = 2), and high-grade soft tissue sarcoma (n = 2). All patients were staged as IIB according to the Enneking system, except for one case of Ewing's sarcoma (stage III). Neoadjuvant chemotherapy (four cycles) was administered to six osteosarcoma patients, and one Ewing's sarcoma patient received six cycles, while other patients proceeded directly to surgery. Patient outcomes were systematically evaluated through oncological status, functional performance (MSTS-93 score), pain assessment (VAS score), surgical parameters, complications, and radiographic analysis using Tomosynthesis Shimadzu Metal Artifact Reduction Technology (T-SMART).</p><p><strong>Results: </strong>At the latest follow-up (44.5 ± 9.4 months), 13 patients (86.7%) remained disease-free; one patient (6.7%) experienced local recurrence requiring revision surgery, and one patient (6.7%) died of metastatic complications at 32 months post-surgery. Functional outcomes showed significant improvement, with mean MSTS-93 scores increasing from 14.5 ± 1.1 preoperatively to 25.8 ± 1.3 at final follow-up (p < 0.001). Pain control was satisfactory, with VAS scores decreasing from 5.5 ± 0.6 to 1.5 ± 0.5 (p < 0.001). The mean surgical duration was 289.3 ± 30.4 min, with an average intraoperative blood loss of 3540 ± 621.5 mL. Early complications included delayed wound healing in three cases (20%), successfully managed with wound care protocols and VAC therapy. One patient (6.7%) developed deep prosthetic infection at 14 months post-surgery, necessitating a two-stage revision procedure. No mechanical failures, aseptic loosening, or prosthesis fractures were observed during the follow-up period. Radiographic analysis demonstrated progressive bone ingrowth into the RCS porous regions in all cases, with no signs of osteolysis or implant migration in the remaining prostheses.</p><p><strong>Conclusion: </strong>D-printed custom hemipelvic prostheses with RCS offer an effective solution for pelvic reconstruction by achieving an optimal balance between mechanical stability and biological integration, leading to promising clinical outcomes.</
{"title":"Clinical Application of 3D-Printed Custom Hemipelvic Prostheses With Re-Entrant Chiral Structure in Reconstruction After Pelvic Tumor Resection.","authors":"Linyun Tan, Ye Li, Xin Hu, Yitian Wang, Xiaolu Zhang, Xiaoyan Liu, Yi Luo, Yong Zhou, Chongqi Tu, Xiao Yang, Li Min","doi":"10.1111/os.70159","DOIUrl":"10.1111/os.70159","url":null,"abstract":"<p><strong>Objectives: </strong>Pelvic reconstruction with conventional 3D-printed prostheses faces a critical trade-off, where achieving sufficient porosity for optimal bone ingrowth often compromises essential mechanical stability. To address this challenge, this study evaluates the clinical outcomes of 3D-printed hemipelvic prostheses incorporating re-entrant chiral structure (RCS), a novel negative Poisson's ratio design, in patients undergoing pelvic reconstruction following tumor resection.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on 15 patients (eight females and seven males; mean age: 39.3 ± 11.7 years) with pelvic malignancies who underwent reconstruction using 3D-printed hemipelvic prostheses incorporating RCS between March 2018 and June 2023. The diagnoses included osteosarcoma (n = 8), Ewing's sarcoma (n = 3), chondrosarcoma (n = 2), and high-grade soft tissue sarcoma (n = 2). All patients were staged as IIB according to the Enneking system, except for one case of Ewing's sarcoma (stage III). Neoadjuvant chemotherapy (four cycles) was administered to six osteosarcoma patients, and one Ewing's sarcoma patient received six cycles, while other patients proceeded directly to surgery. Patient outcomes were systematically evaluated through oncological status, functional performance (MSTS-93 score), pain assessment (VAS score), surgical parameters, complications, and radiographic analysis using Tomosynthesis Shimadzu Metal Artifact Reduction Technology (T-SMART).</p><p><strong>Results: </strong>At the latest follow-up (44.5 ± 9.4 months), 13 patients (86.7%) remained disease-free; one patient (6.7%) experienced local recurrence requiring revision surgery, and one patient (6.7%) died of metastatic complications at 32 months post-surgery. Functional outcomes showed significant improvement, with mean MSTS-93 scores increasing from 14.5 ± 1.1 preoperatively to 25.8 ± 1.3 at final follow-up (p < 0.001). Pain control was satisfactory, with VAS scores decreasing from 5.5 ± 0.6 to 1.5 ± 0.5 (p < 0.001). The mean surgical duration was 289.3 ± 30.4 min, with an average intraoperative blood loss of 3540 ± 621.5 mL. Early complications included delayed wound healing in three cases (20%), successfully managed with wound care protocols and VAC therapy. One patient (6.7%) developed deep prosthetic infection at 14 months post-surgery, necessitating a two-stage revision procedure. No mechanical failures, aseptic loosening, or prosthesis fractures were observed during the follow-up period. Radiographic analysis demonstrated progressive bone ingrowth into the RCS porous regions in all cases, with no signs of osteolysis or implant migration in the remaining prostheses.</p><p><strong>Conclusion: </strong>D-printed custom hemipelvic prostheses with RCS offer an effective solution for pelvic reconstruction by achieving an optimal balance between mechanical stability and biological integration, leading to promising clinical outcomes.</","PeriodicalId":19566,"journal":{"name":"Orthopaedic Surgery","volume":" ","pages":"3067-3077"},"PeriodicalIF":2.1,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12580219/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144963824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-01Epub Date: 2025-09-26DOI: 10.1111/os.70175
Lucrezia Moggio, Nicola Marotta, Alessandro de Sire, Giorgia Lucia Benedetto, Giorgio Gasparini, Antonio Ammendolia, Elvira Immacolata Parrotta, Michele Mercurio
Objective: Rotator cuff calcific tendinopathy is a leading cause of nontraumatic shoulder pain, frequently leading to articular and functional impairments, depicting an adhesive capsulitis-like clinical presentation. To date, there is a lack of evidence on the impact of conservative approaches, and no gold standard has been established for managing rotator cuff calcific tendinopathy. This systematic review aimed to identify the most effective conservative approach for reducing pain and improving function in rotator cuff calcific tendinopathy patients.
Methods: PubMed, Scopus, and Cochrane Library databases were systematically searched from their inception until January 2, 2025, for English-language randomized clinical trials including adults affected by rotator cuff calcific tendinopathy undergoing conservative treatment. Data extraction was performed independently by two reviewers using a customized data extraction form, with consensus reached by a third reviewer. A network meta-analysis was subsequently carried out to compare the efficacy of different interventions. The risk of bias within the included randomized clinical trials was assessed using Version 2 of the Cochrane risk-of-bias tool for randomized trials. The study has been registered with PROSPERO, registration number CRD420250650833.
Results: Nineteen articles were included. This study identified 1160 subjects affected by rotator cuff calcific tendinopathy. A pairwise comparison through a network meta-analysis indicated that platelet-rich plasma exhibited the highest probability (85%) of improving shoulder function, followed by disodium ethylenediamine tetra-acetic acid at 75%, aspiration techniques at 65%, and extracorporeal shockwave therapy at 57%. Regarding pain reduction, disodium ethylenediamine tetra-acetic acid showed the highest probability (66%), followed by kinesiotaping and needle aspiration, both at 61%.
Conclusion: This systematic review and network meta-analysis identified several interventional techniques, including platelet-rich plasma and disodium ethylenediamine tetra-acetic acid injections, extracorporeal shockwave therapy, and needle aspiration, as more effective strategies for reducing pain and improving function in subjects affected by rotator cuff calcific tendinopathy.
Level of evidence: I (systematic review of Level-I randomized controlled studies).
{"title":"Efficacy of Conservative Approaches on Pain Relief and Function in Patients With Rotator Cuff Calcific Tendinopathy: Which Is the Best Option? A Systematic Review and Network Meta-Analysis.","authors":"Lucrezia Moggio, Nicola Marotta, Alessandro de Sire, Giorgia Lucia Benedetto, Giorgio Gasparini, Antonio Ammendolia, Elvira Immacolata Parrotta, Michele Mercurio","doi":"10.1111/os.70175","DOIUrl":"10.1111/os.70175","url":null,"abstract":"<p><strong>Objective: </strong>Rotator cuff calcific tendinopathy is a leading cause of nontraumatic shoulder pain, frequently leading to articular and functional impairments, depicting an adhesive capsulitis-like clinical presentation. To date, there is a lack of evidence on the impact of conservative approaches, and no gold standard has been established for managing rotator cuff calcific tendinopathy. This systematic review aimed to identify the most effective conservative approach for reducing pain and improving function in rotator cuff calcific tendinopathy patients.</p><p><strong>Methods: </strong>PubMed, Scopus, and Cochrane Library databases were systematically searched from their inception until January 2, 2025, for English-language randomized clinical trials including adults affected by rotator cuff calcific tendinopathy undergoing conservative treatment. Data extraction was performed independently by two reviewers using a customized data extraction form, with consensus reached by a third reviewer. A network meta-analysis was subsequently carried out to compare the efficacy of different interventions. The risk of bias within the included randomized clinical trials was assessed using Version 2 of the Cochrane risk-of-bias tool for randomized trials. The study has been registered with PROSPERO, registration number CRD420250650833.</p><p><strong>Results: </strong>Nineteen articles were included. This study identified 1160 subjects affected by rotator cuff calcific tendinopathy. A pairwise comparison through a network meta-analysis indicated that platelet-rich plasma exhibited the highest probability (85%) of improving shoulder function, followed by disodium ethylenediamine tetra-acetic acid at 75%, aspiration techniques at 65%, and extracorporeal shockwave therapy at 57%. Regarding pain reduction, disodium ethylenediamine tetra-acetic acid showed the highest probability (66%), followed by kinesiotaping and needle aspiration, both at 61%.</p><p><strong>Conclusion: </strong>This systematic review and network meta-analysis identified several interventional techniques, including platelet-rich plasma and disodium ethylenediamine tetra-acetic acid injections, extracorporeal shockwave therapy, and needle aspiration, as more effective strategies for reducing pain and improving function in subjects affected by rotator cuff calcific tendinopathy.</p><p><strong>Level of evidence: </strong>I (systematic review of Level-I randomized controlled studies).</p>","PeriodicalId":19566,"journal":{"name":"Orthopaedic Surgery","volume":" ","pages":"3048-3066"},"PeriodicalIF":2.1,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12580237/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145150326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: Conversion to hip arthroplasty (cHA) is a widely utilized and effective surgical intervention for addressing the failure of internal fixation in intertrochanteric femoral fractures (FIF-INF). Although previous studies have confirmed that the failure rate of internal fixation is higher in unstable intertrochanteric femoral fractures, but whether the efficacy and complications of cHA after failure differ from those in stable fractures remains unclear. This study aimed to evaluate and compare the clinical and radiological outcomes, as well as the incidence of complications associated with hip arthroplasty over a minimum follow-up period of 3 years after the failure of internal fixation in both stable and unstable intertrochanteric femoral fractures.
Methods: This multicenter study retrospectively analyzed patients who underwent hip arthroplasty subsequent to the failure of FIF-INF from December 2012 to December 2020 at various participating research centers. Cases demonstrating excellent and acceptable quality fracture reduction, as defined by the criteria established by Chang et al., were included. According to AO/OTA classification criteria of intertrochanteric fractures, the fractures were classified into stable fractures (31-A1) and unstable fractures (31-A2, A3). There were 47 patients with stable fractures and 56 patients with unstable fractures. Clinical and radiological evaluations were conducted for all patients. This study employed independent samples t-tests, χ 2 tests or Fisher's exact test, and both univariate and multivariate logistic regression analyses.
Results: A total of 103 patients were analyzed. The HHS in the stable group improved from a preoperative mean of 47.08 ± 5.50 to 89.13 ± 4.75 at the final follow-up, whereas that in the unstable group increased from 45.43 ± 6.36 to 83.87 ± 4.67. The improvement scores for the stable and unstable groups were 42.05 ± 4.69 and 38.81 ± 3.06, respectively, with a statistically significant difference (p < 0.0001). VAS scores decreased from the preoperative levels of 7.13 ± 0.92 and 7.61 ± 0.82 to 2.36 ± 0.87 and 2.91 ± 0.79, respectively, indicating a significant reduction in pain in both groups; however, the unstable group reported more severe postoperative pain (p = 0.001). The incidence of postoperative complications following cHA was significantly greater in the unstable group (28.57%) than in the stable group (10.64%) (p = 0.047).
Conclusion: cHA is an effective treatment modality for the failure of internal fixation in intertrochanteric femoral fractures. Compared with stable fractures, patients with initial unstable fractures that have failed experience a greater incidence of postoperative complications, relatively poorer joint function, and more pronounced pain following cHA.
{"title":"Effects and Complications of Hip Arthroplasty After Failure of Internal Fixation in Stable and Unstable Intertrochanteric Femoral Fractures.","authors":"Juncheng Li, Canhong Zhang, Lan Lin, Nanxin Zhang, Jiexin Huang, Zida Huang, Huangfeng Lin, Hongxiang Wei, Haiqi Ding, Shaopeng Lin, Wenming Zhang, Xinyu Fang, Jiagu Huang","doi":"10.1111/os.70184","DOIUrl":"10.1111/os.70184","url":null,"abstract":"<p><strong>Objective: </strong>Conversion to hip arthroplasty (cHA) is a widely utilized and effective surgical intervention for addressing the failure of internal fixation in intertrochanteric femoral fractures (FIF-INF). Although previous studies have confirmed that the failure rate of internal fixation is higher in unstable intertrochanteric femoral fractures, but whether the efficacy and complications of cHA after failure differ from those in stable fractures remains unclear. This study aimed to evaluate and compare the clinical and radiological outcomes, as well as the incidence of complications associated with hip arthroplasty over a minimum follow-up period of 3 years after the failure of internal fixation in both stable and unstable intertrochanteric femoral fractures.</p><p><strong>Methods: </strong>This multicenter study retrospectively analyzed patients who underwent hip arthroplasty subsequent to the failure of FIF-INF from December 2012 to December 2020 at various participating research centers. Cases demonstrating excellent and acceptable quality fracture reduction, as defined by the criteria established by Chang et al., were included. According to AO/OTA classification criteria of intertrochanteric fractures, the fractures were classified into stable fractures (31-A1) and unstable fractures (31-A2, A3). There were 47 patients with stable fractures and 56 patients with unstable fractures. Clinical and radiological evaluations were conducted for all patients. This study employed independent samples t-tests, χ <sup>2</sup> tests or Fisher's exact test, and both univariate and multivariate logistic regression analyses.</p><p><strong>Results: </strong>A total of 103 patients were analyzed. The HHS in the stable group improved from a preoperative mean of 47.08 ± 5.50 to 89.13 ± 4.75 at the final follow-up, whereas that in the unstable group increased from 45.43 ± 6.36 to 83.87 ± 4.67. The improvement scores for the stable and unstable groups were 42.05 ± 4.69 and 38.81 ± 3.06, respectively, with a statistically significant difference (p < 0.0001). VAS scores decreased from the preoperative levels of 7.13 ± 0.92 and 7.61 ± 0.82 to 2.36 ± 0.87 and 2.91 ± 0.79, respectively, indicating a significant reduction in pain in both groups; however, the unstable group reported more severe postoperative pain (p = 0.001). The incidence of postoperative complications following cHA was significantly greater in the unstable group (28.57%) than in the stable group (10.64%) (p = 0.047).</p><p><strong>Conclusion: </strong>cHA is an effective treatment modality for the failure of internal fixation in intertrochanteric femoral fractures. Compared with stable fractures, patients with initial unstable fractures that have failed experience a greater incidence of postoperative complications, relatively poorer joint function, and more pronounced pain following cHA.</p>","PeriodicalId":19566,"journal":{"name":"Orthopaedic Surgery","volume":" ","pages":"3262-3271"},"PeriodicalIF":2.1,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12580236/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145280740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}