Mokhlesur R. M, Tahmid C. A, Hassan S, Zubaer M, Awang M, Hasan M
The plant is also known as hemp, although this term is often used only to refer to varieties of cannabis cultivated for non-drug use. Cannabis has long been used as hemp fiber, hemp seeds and their oil, hemp leaves as vegetable and juice, for medicinal purposes and as a recreational drug. It has been widely used specifically in incense, peaceful sleep for cancer affected patients and traditional medicine. Its common uses include treating knee joint pain, inflammatory-related complaints, diarrhea, and a tonic, sedative, and cardio caring agent. Cannabis sativa is the hemp plant from which marijuana and cannabinoids (leaves, stems, seeds) are derived. The most potent form of this plant's extracts is hash oil, a liquid. Quantum computing, on the other hand, offers unprecedented computational power and can revolutionize various scientific fields. The study's goal is to explore the potential of quantum computing to enhance the extraction process. By employing quantum algorithms, the project aims to optimize critical parameters such as pressure, temperature, and extraction time, leading to improved efficiency and higher yields. Quantum simulations will model the behavior of CO2 as a supercritical fluid within the cannabis matrix, supplying insights into the complex dynamics of the extraction process. Finally, the use of quantum algorithms promises to ease the development of more efficient and sustainable extraction methods, resulting in the production of high-quality cannabis-derived products with enhanced medicinal and industrial applications.
{"title":"Enhancing Cannabis Extraction Efficiency and Sustainability through Quantum Computing: A Review","authors":"Mokhlesur R. M, Tahmid C. A, Hassan S, Zubaer M, Awang M, Hasan M","doi":"10.13005/ojc/390604","DOIUrl":"https://doi.org/10.13005/ojc/390604","url":null,"abstract":"The plant is also known as hemp, although this term is often used only to refer to varieties of cannabis cultivated for non-drug use. Cannabis has long been used as hemp fiber, hemp seeds and their oil, hemp leaves as vegetable and juice, for medicinal purposes and as a recreational drug. It has been widely used specifically in incense, peaceful sleep for cancer affected patients and traditional medicine. Its common uses include treating knee joint pain, inflammatory-related complaints, diarrhea, and a tonic, sedative, and cardio caring agent. Cannabis sativa is the hemp plant from which marijuana and cannabinoids (leaves, stems, seeds) are derived. The most potent form of this plant's extracts is hash oil, a liquid. Quantum computing, on the other hand, offers unprecedented computational power and can revolutionize various scientific fields. The study's goal is to explore the potential of quantum computing to enhance the extraction process. By employing quantum algorithms, the project aims to optimize critical parameters such as pressure, temperature, and extraction time, leading to improved efficiency and higher yields. Quantum simulations will model the behavior of CO2 as a supercritical fluid within the cannabis matrix, supplying insights into the complex dynamics of the extraction process. Finally, the use of quantum algorithms promises to ease the development of more efficient and sustainable extraction methods, resulting in the production of high-quality cannabis-derived products with enhanced medicinal and industrial applications.","PeriodicalId":19599,"journal":{"name":"Oriental Journal Of Chemistry","volume":"113 4","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139153955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
An environment eco-friendly adsorbents such as filtrasorb-816 and filtrasorb-820 were used in this work. For the evaluation of the adsorption of manganese from the aqueous phase, granular activated carbons were used in conjunction with organic ligands such as 3,5-Dinitrobenzoic acid. The phenomenon of adsorption characteristics of manganese in an aqueous phase was studied at a constant temperature of 25 ±1℃ C and pH 5. Granular activated carbons were characterized by SEM analysis. Experimental data were tested by using Pseudo first and Pseudo second-order kinetic models. From the results, it was investigated that Pesudo second-order data is more favorable than the pseudo-first-order for this system. The Langmuir, Freundlich, and Temkin isotherms models were used to describe the equilibrium characteristics of adsorption of Mn2+ onto activated carbon but the R2 value of the Langmuir isotherm model was higher than other isotherms and hence it is the best fit. From this study, it was found that F-820 has more adsorption capacity to scavenge Mn2+ than F-816 from aqueous phase
{"title":"Utilization of Granular Activated Carbon for Sustainable Environmental Contaminants Remediation","authors":"Y. K. Meshram, R. U. Khope, Reshal A. Deshmukh","doi":"10.13005/ojc/390631","DOIUrl":"https://doi.org/10.13005/ojc/390631","url":null,"abstract":"An environment eco-friendly adsorbents such as filtrasorb-816 and filtrasorb-820 were used in this work. For the evaluation of the adsorption of manganese from the aqueous phase, granular activated carbons were used in conjunction with organic ligands such as 3,5-Dinitrobenzoic acid. The phenomenon of adsorption characteristics of manganese in an aqueous phase was studied at a constant temperature of 25 ±1℃ C and pH 5. Granular activated carbons were characterized by SEM analysis. Experimental data were tested by using Pseudo first and Pseudo second-order kinetic models. From the results, it was investigated that Pesudo second-order data is more favorable than the pseudo-first-order for this system. The Langmuir, Freundlich, and Temkin isotherms models were used to describe the equilibrium characteristics of adsorption of Mn2+ onto activated carbon but the R2 value of the Langmuir isotherm model was higher than other isotherms and hence it is the best fit. From this study, it was found that F-820 has more adsorption capacity to scavenge Mn2+ than F-816 from aqueous phase","PeriodicalId":19599,"journal":{"name":"Oriental Journal Of Chemistry","volume":"118 17","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139154810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A novel ligand (E)-7-hydroxy-4-methyl-8-(1-(naphthalen-1-ylimino) ethyl)-2H-chromen-2-one [HOMNIEC] was synthesized by condensation of 8-acetyl-7-hydroxy-4-methyl-2H-chromen-2-one and Naphthalen-1-amine by the reported method. The metal complexes with this ligand were synthesized by using a common new method. FTIR, 1H NMR, Mass Spectrometry and TGA techniques were used to confirm their structures. The FTIR spectral data indicate that the ligand was coordinated with the metal ions through the phenolic oxygen on coumarin moiety and nitrogen of azomethine. The ligand and complexes were examined for in vitro antimicrobial activities using broth microdilution method in DMSO medium against Escherichia Coli (MTCC 443) and Pseudomonas Aeruginosa (MTCC 1688) a gram-negative bacterial strain, Staphylococcus Aureus (MTCC 96) and Streptococcus Pyogenes (MTCC 442) a gram-positive bacterial strain, and Candida Albicans (MTCC 227), Aspergillus Clavatus (MTCC 1323) and Aspergillus Niger (MTCC 280) fungal strains. The metal complexes were found to have enhanced antimicrobial activities compare to the Schiff base [HOMNIEC] ligand. Especially, the antifungal activity of Cu(II) and Zn(II) ions complexes was found to be twofold more than the standard drug griseofulvin against C. Albicans.
{"title":"Synthesis, Structures and Antimicrobial Activities of Novel Schiff Base Ligand and Its Metal Complexes","authors":"S. Adhao, Rahul Ramchandra Wagh","doi":"10.13005/ojc/390617","DOIUrl":"https://doi.org/10.13005/ojc/390617","url":null,"abstract":"A novel ligand (E)-7-hydroxy-4-methyl-8-(1-(naphthalen-1-ylimino) ethyl)-2H-chromen-2-one [HOMNIEC] was synthesized by condensation of 8-acetyl-7-hydroxy-4-methyl-2H-chromen-2-one and Naphthalen-1-amine by the reported method. The metal complexes with this ligand were synthesized by using a common new method. FTIR, 1H NMR, Mass Spectrometry and TGA techniques were used to confirm their structures. The FTIR spectral data indicate that the ligand was coordinated with the metal ions through the phenolic oxygen on coumarin moiety and nitrogen of azomethine. The ligand and complexes were examined for in vitro antimicrobial activities using broth microdilution method in DMSO medium against Escherichia Coli (MTCC 443) and Pseudomonas Aeruginosa (MTCC 1688) a gram-negative bacterial strain, Staphylococcus Aureus (MTCC 96) and Streptococcus Pyogenes (MTCC 442) a gram-positive bacterial strain, and Candida Albicans (MTCC 227), Aspergillus Clavatus (MTCC 1323) and Aspergillus Niger (MTCC 280) fungal strains. The metal complexes were found to have enhanced antimicrobial activities compare to the Schiff base [HOMNIEC] ligand. Especially, the antifungal activity of Cu(II) and Zn(II) ions complexes was found to be twofold more than the standard drug griseofulvin against C. Albicans.","PeriodicalId":19599,"journal":{"name":"Oriental Journal Of Chemistry","volume":"159 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139153833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D.China Babu, M. Alagusundaram, G. S. S. Harsha, Shailender Sing Nerwarya, G. Venkateshwarlu, A. Parameswari, SK. Aleesha
Background: Lasmiditan is an agonist of 5HT1F receptor, acute migraine is treated and oral dose is safe and effective. No analytical methods were reported on Lasmiditan Drug. Objectives: The goal of the current project is to create a quick, effective, and reproducible LC/MS/MS method for the estimation of Lasmiditan. The mobile phase was used Acetonitrile: 0.1% formic acid (70:30) in the developed method, and it was running down a C18 column (SP) with dimensions of 150 mm, 4.6 mm i.d., and 3.5 µm at a rate of 1 mL/min. The [M+H]+ ion m/z ratio for the substance was observed in the mass spectrum was 378.24. The drug had a retention time of 2.3 minutes. The linearity range was found to be in between 12.50 ng/mL and 75 ng/mL. The regression coefficient value was found to be 0.999, which is good satisfactory value for linearity. The LOD and LOQ for baseline measurement and detection were 0.66 ng/mL and 2.22 ng/mL, respectively; the method was shown good accuracy and precision levels, and it was proved through the assay values. The method was proved as robust after deliberated changes in parameters of flow rate (±0.2mL) and organic phase (±3 mL) in mobile phase composition and values were found to be 99.50%-100.73% & 99.10%- 101.83% respectively. Conclusion: The LC/MS/MS method is more advanced and sensitive to determine the drugs at nanograms level. Hence developed method used for the regular assay. This is more sensitive, selective, and rapid for identification and quantification of LMT in the bulk and Pharmaceutical formulation.
{"title":"LC/MS/MS Method Development and Validation for the Estimation of Lasmiditan in Bulk and Pharmaceutical Formulation","authors":"D.China Babu, M. Alagusundaram, G. S. S. Harsha, Shailender Sing Nerwarya, G. Venkateshwarlu, A. Parameswari, SK. Aleesha","doi":"10.13005/ojc/390625","DOIUrl":"https://doi.org/10.13005/ojc/390625","url":null,"abstract":"Background: Lasmiditan is an agonist of 5HT1F receptor, acute migraine is treated and oral dose is safe and effective. No analytical methods were reported on Lasmiditan Drug. Objectives: The goal of the current project is to create a quick, effective, and reproducible LC/MS/MS method for the estimation of Lasmiditan. The mobile phase was used Acetonitrile: 0.1% formic acid (70:30) in the developed method, and it was running down a C18 column (SP) with dimensions of 150 mm, 4.6 mm i.d., and 3.5 µm at a rate of 1 mL/min. The [M+H]+ ion m/z ratio for the substance was observed in the mass spectrum was 378.24. The drug had a retention time of 2.3 minutes. The linearity range was found to be in between 12.50 ng/mL and 75 ng/mL. The regression coefficient value was found to be 0.999, which is good satisfactory value for linearity. The LOD and LOQ for baseline measurement and detection were 0.66 ng/mL and 2.22 ng/mL, respectively; the method was shown good accuracy and precision levels, and it was proved through the assay values. The method was proved as robust after deliberated changes in parameters of flow rate (±0.2mL) and organic phase (±3 mL) in mobile phase composition and values were found to be 99.50%-100.73% & 99.10%- 101.83% respectively. Conclusion: The LC/MS/MS method is more advanced and sensitive to determine the drugs at nanograms level. Hence developed method used for the regular assay. This is more sensitive, selective, and rapid for identification and quantification of LMT in the bulk and Pharmaceutical formulation.","PeriodicalId":19599,"journal":{"name":"Oriental Journal Of Chemistry","volume":"115 3","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139153953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Syed Kashif Ali, G. Gambhir, G. Khuwaja, Sayeed Shabi, Safaa F. Saleh, Angum M M Ibrahim, Amal. A. Noureideen, Mawada Abubaker Abdelgadir Mohammed
Selective determination of caffeic acid, was carried out by using Screen Printed Carbon Electrode (SPCE) to give a reliable, scalable, and inexpensive electrochemical method with enhanced analytical performance. SPCE was first activated by linear sweep voltammetry using KOH solution, followed by its electrochemical grafting with cyclodextrins. Britton Robinson buffer (BRB) solution having pH 8.1, demonstrated a clear electrocatalytic impact towards caffeic acid oxidation, which indicated a greater current response compared to the activated electrode in the cyclic voltammetric and square wave voltammetric (SWV) investigations. The SWV waves at the activated SPCE was used under ideal conditions to produce a linear calibration curve with detection limits of (LoD, 4 sb/m) and quantification limits of (LoQ, 11 sb/m) of 0.38 M and 1.1 M, respectively.
{"title":"Determination of Caffeic acid in Cigarette Smoke and Urine by Electrochemical Methods Using Supramolecular Electroactive Materials grafted in Screen Printed Carbon Electrode","authors":"Syed Kashif Ali, G. Gambhir, G. Khuwaja, Sayeed Shabi, Safaa F. Saleh, Angum M M Ibrahim, Amal. A. Noureideen, Mawada Abubaker Abdelgadir Mohammed","doi":"10.13005/ojc/390606","DOIUrl":"https://doi.org/10.13005/ojc/390606","url":null,"abstract":"Selective determination of caffeic acid, was carried out by using Screen Printed Carbon Electrode (SPCE) to give a reliable, scalable, and inexpensive electrochemical method with enhanced analytical performance. SPCE was first activated by linear sweep voltammetry using KOH solution, followed by its electrochemical grafting with cyclodextrins. Britton Robinson buffer (BRB) solution having pH 8.1, demonstrated a clear electrocatalytic impact towards caffeic acid oxidation, which indicated a greater current response compared to the activated electrode in the cyclic voltammetric and square wave voltammetric (SWV) investigations. The SWV waves at the activated SPCE was used under ideal conditions to produce a linear calibration curve with detection limits of (LoD, 4 sb/m) and quantification limits of (LoQ, 11 sb/m) of 0.38 M and 1.1 M, respectively.","PeriodicalId":19599,"journal":{"name":"Oriental Journal Of Chemistry","volume":"100 8","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139154142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Natural Guar gum based resin which containing 6-amino caproic acid as a functional group has been synthesized. This modified ion exchange resin was used for removal of toxic metal ions from synthetic waste water using the principle of ion exchange mechanism. GACA resin was used for removal of Zn (II) and Co (II) metal ions from aqueous solution containing these metal ions. Zn (II) ion show maximum adsorption and Kd value at pH 5 while Co (II) show at pH 6. Zn (II) show maximum adsorption on GACA resin is 81.34% and for Co (II) is 73.3% which is good result.
合成了以天然瓜尔胶为基础的树脂，其中含有作为官能团的 6-氨基己酸。利用离子交换机理原理，这种改性离子交换树脂被用于去除合成废水中的有毒金属离子。GACA 树脂用于从含有 Zn (II) 和 Co (II) 金属离子的水溶液中去除这些金属离子。锌（II）离子在 pH 值为 5 时的吸附量和 Kd 值最大，而钴（II）离子在 pH 值为 6 时的吸附量和 Kd 值最大。锌（II）离子在 GACA 树脂上的最大吸附量为 81.34%，而钴（II）离子在 GACA 树脂上的最大吸附量为 73.3%，结果良好。
{"title":"Applications of Guar gum 6-amino Caproic acid (GACA) Resin for Extraction of Cobalt and Zinc Metal Ions from References Waste Water Using Batch Method","authors":"Punam Singh Bhati, Ishwar Singh, A. V. Singh","doi":"10.13005/ojc/390611","DOIUrl":"https://doi.org/10.13005/ojc/390611","url":null,"abstract":"Natural Guar gum based resin which containing 6-amino caproic acid as a functional group has been synthesized. This modified ion exchange resin was used for removal of toxic metal ions from synthetic waste water using the principle of ion exchange mechanism. GACA resin was used for removal of Zn (II) and Co (II) metal ions from aqueous solution containing these metal ions. Zn (II) ion show maximum adsorption and Kd value at pH 5 while Co (II) show at pH 6. Zn (II) show maximum adsorption on GACA resin is 81.34% and for Co (II) is 73.3% which is good result.","PeriodicalId":19599,"journal":{"name":"Oriental Journal Of Chemistry","volume":"20 S31","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139154632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In the present communication we are reporting experimentally observed data of Platinum (Pt) based nano composite thin films. Platinum (Pt) shows crystalline behavior whereas Antimony tri sulfide (Sb2S3) shows amorphous behavior, and it has layered structure. In this observation the ratio of Pt and Sb2S3 is taken in 1:10 respectively, due to which multiple peaks shown in X-ray Diffraction (XRD) and have studied its variation by doing UV-VIS spectroscopy of different thickness of deposited material. Therefore, by this analysis of the nano composite materials we can synthesize nanomaterials which have great applications in photodetectors, solar cells, drug delivery, Fuel Cell, sensors, bioimaging and many other materials fabrications.
在这篇通讯中，我们报告了基于铂（Pt）的纳米复合薄膜的实验观测数据。铂（Pt）呈晶体状，而三硫化锑（Sb2S3）呈无定形状，具有层状结构。在这次观察中，铂和三硫化二锑（Sb2S3）的比例分别为 1:10，因此在 X 射线衍射（XRD）中会出现多个峰值，我们还通过对不同厚度的沉积材料进行紫外可见光谱分析来研究其变化。因此，通过对纳米复合材料的分析，我们可以合成在光电探测器、太阳能电池、药物输送、燃料电池、传感器、生物成像和许多其他材料制造中具有重要应用价值的纳米材料。
{"title":"Characterization of Platinum (Pt) Based Nanocomposite Thin films","authors":"S. P. Singh, U. C. Srivastava","doi":"10.13005/ojc/390634","DOIUrl":"https://doi.org/10.13005/ojc/390634","url":null,"abstract":"In the present communication we are reporting experimentally observed data of Platinum (Pt) based nano composite thin films. Platinum (Pt) shows crystalline behavior whereas Antimony tri sulfide (Sb2S3) shows amorphous behavior, and it has layered structure. In this observation the ratio of Pt and Sb2S3 is taken in 1:10 respectively, due to which multiple peaks shown in X-ray Diffraction (XRD) and have studied its variation by doing UV-VIS spectroscopy of different thickness of deposited material. Therefore, by this analysis of the nano composite materials we can synthesize nanomaterials which have great applications in photodetectors, solar cells, drug delivery, Fuel Cell, sensors, bioimaging and many other materials fabrications.","PeriodicalId":19599,"journal":{"name":"Oriental Journal Of Chemistry","volume":"4 5","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139153727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Ghai, S. Chaudhary, Kandasamy Nagarajan, Richa Goel, Shardendu Kumar Mishra, Naveen Kumar Tholia, Nazakat Ali, Monika Kaurav
Obesity is stated to be a notable concern for public health and plays a significant role in the development of numerous non-communicable diseases (NCDs), including conditions affecting the heart, metabolism, and the nervous system. The use of medicinal plants to maintain normal weight and excellent health has been researched for a very long time. However, sufficient empirical data are still lacking to support the scientific notion of the use of herbal products for weight management. Obesity has traditionally been treated with herbal remedies from both domestic and international sources, including Ayurveda (Indian Traditional Medicine System). This article provides a brief overview of obesity-related disorders and their epidemiology, then discusses the potential anti-obesity effects of plants including Salvia plebian, Glycine max, Curcuma longa, Camellia sinensis, Moringa citrifolia, and others using validated tested animal models. It also focuses on the active phytochemical components that give these substances their anti-obesity properties, such as daidzein, ginsenosides, curcuminoids, zingiberene, curcumene, and ellagitannin. The paper was compiled after going through marketed formulations used worldwide, clinical trials and patents based on herbal products for obesity. This review can assist numerous researchers in conducting additional research on exploring the potential.
{"title":"An Investigative Study of Medicinal Herbs for Anti-obesity Potential: (A-Review)","authors":"R. Ghai, S. Chaudhary, Kandasamy Nagarajan, Richa Goel, Shardendu Kumar Mishra, Naveen Kumar Tholia, Nazakat Ali, Monika Kaurav","doi":"10.13005/ojc/390605","DOIUrl":"https://doi.org/10.13005/ojc/390605","url":null,"abstract":"Obesity is stated to be a notable concern for public health and plays a significant role in the development of numerous non-communicable diseases (NCDs), including conditions affecting the heart, metabolism, and the nervous system. The use of medicinal plants to maintain normal weight and excellent health has been researched for a very long time. However, sufficient empirical data are still lacking to support the scientific notion of the use of herbal products for weight management. Obesity has traditionally been treated with herbal remedies from both domestic and international sources, including Ayurveda (Indian Traditional Medicine System). This article provides a brief overview of obesity-related disorders and their epidemiology, then discusses the potential anti-obesity effects of plants including Salvia plebian, Glycine max, Curcuma longa, Camellia sinensis, Moringa citrifolia, and others using validated tested animal models. It also focuses on the active phytochemical components that give these substances their anti-obesity properties, such as daidzein, ginsenosides, curcuminoids, zingiberene, curcumene, and ellagitannin. The paper was compiled after going through marketed formulations used worldwide, clinical trials and patents based on herbal products for obesity. This review can assist numerous researchers in conducting additional research on exploring the potential.","PeriodicalId":19599,"journal":{"name":"Oriental Journal Of Chemistry","volume":"23 3","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139153835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The condensation reaction of Benzil with semicarbazide followed by a triazine ring formation and then subsequent interaction with substituted aromatic aldehydes, resulted in synthesis of aromatic hydrazone derivatives (C1 – C4). These derivatives have been synthesized via greener method using acetic acid rather than conc. Sulfuric acid. The resultant compounds were analyzed using spectral (1H-NMR, IR) and elemental analysis. The in-vitro analysis of these compounds portrayed prominent activity against bacterial and fungal strains.
{"title":"Green Synthesis and Antimicrobial Activities of Some Aromatic Hydrazones","authors":"Vijay Kumar Yadav, Meena Bhandari, Satbir Singh","doi":"10.13005/ojc/390638","DOIUrl":"https://doi.org/10.13005/ojc/390638","url":null,"abstract":"The condensation reaction of Benzil with semicarbazide followed by a triazine ring formation and then subsequent interaction with substituted aromatic aldehydes, resulted in synthesis of aromatic hydrazone derivatives (C1 – C4). These derivatives have been synthesized via greener method using acetic acid rather than conc. Sulfuric acid. The resultant compounds were analyzed using spectral (1H-NMR, IR) and elemental analysis. The in-vitro analysis of these compounds portrayed prominent activity against bacterial and fungal strains.","PeriodicalId":19599,"journal":{"name":"Oriental Journal Of Chemistry","volume":"27 107","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139154604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mayur Porwal, Phool Chandra, Vivek Kumar, Navneet Verma, Km. Monika
A wide range of experiments have yielded empirical evidence pertaining to the efficacy of medicinal plants in the therapeutic treatment of several disorders. However, the use of herbs without conducting a thorough assessment of their effectiveness and safety can lead to sudden or harmful consequences that may pose a risk to the overall health of internal organs. Therefore, the current investigation’s goal was to determine the ethanolic extract of Litchi chinensis toxicological profile in rats. The Soxhlet extraction method extracted the fruit with ethanol as a solvent. The extract's susceptibility to acute, subacute, and subchronic toxicity was assessed. The histopathology of several organs (e.g., heart, liver, lungs, kidney and spleen) were also studied after treatment with plant extract. With the dosage of 2000 mg/kg, p.o., no deaths or adverse consequences were reported during the examination of acute toxicity. The Litchi chinensis extract produced no death or any observable changes in weight, behavior, organ weights, hematological or biochemical values in both oral subacute and subchronic toxicity experiments. Essential organs, including the heart, liver, lungs, kidney, and spleen, have regular planning when examined histopathologically, indicating no morphological changes. On the basis of results, the fruit (pericarp) extract of Litchi chinensis showed a lack of toxicity.
{"title":"Evaluation of the Oral Toxicity of Litchi chinensis Pericarp Extract in Experimental Rats","authors":"Mayur Porwal, Phool Chandra, Vivek Kumar, Navneet Verma, Km. Monika","doi":"10.13005/ojc/390609","DOIUrl":"https://doi.org/10.13005/ojc/390609","url":null,"abstract":"A wide range of experiments have yielded empirical evidence pertaining to the efficacy of medicinal plants in the therapeutic treatment of several disorders. However, the use of herbs without conducting a thorough assessment of their effectiveness and safety can lead to sudden or harmful consequences that may pose a risk to the overall health of internal organs. Therefore, the current investigation’s goal was to determine the ethanolic extract of Litchi chinensis toxicological profile in rats. The Soxhlet extraction method extracted the fruit with ethanol as a solvent. The extract's susceptibility to acute, subacute, and subchronic toxicity was assessed. The histopathology of several organs (e.g., heart, liver, lungs, kidney and spleen) were also studied after treatment with plant extract. With the dosage of 2000 mg/kg, p.o., no deaths or adverse consequences were reported during the examination of acute toxicity. The Litchi chinensis extract produced no death or any observable changes in weight, behavior, organ weights, hematological or biochemical values in both oral subacute and subchronic toxicity experiments. Essential organs, including the heart, liver, lungs, kidney, and spleen, have regular planning when examined histopathologically, indicating no morphological changes. On the basis of results, the fruit (pericarp) extract of Litchi chinensis showed a lack of toxicity.","PeriodicalId":19599,"journal":{"name":"Oriental Journal Of Chemistry","volume":"7 5","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139153874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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