The primary objective of this research was to delve into the forced degradation products of Rilpivirine hydrochloride (RLP HCl), a crucial non-nucleoside reverse transcriptase inhibitor employed inmanagement of epidemic disease named HIV-1. The investigation utilised the probable of RP-HPLC in tandem with peak purity assessment .In order to simulate conceivable degradation pathways, the study encompassed a gamut of stress conditions like acidic, alkaline, oxidative , thermal and photolytic environments. Authors used Agilent zorbaxEclipse XDB C18 column (150x2.1mm, 1.8µm), RLP and impurities were separated. Buffer as pH of 3.0 and acetonitrile in gradient mode (68:32v/v), flow rate of 0.55ml/min. Volume injected is 3µL and detection wavelength is 220 nm. Temperature is maintained at 55oC by 70:30v/v mixture of water and acetonitrile.System suitability was erect to be within the limits. The average percentage recoveries for impurities were 98% to 101%.The outcomes of this meticulous study unveiled the susceptibilities of RLP to a spectrum of stress factors, in the generation of impurity profile RLP-Amide A, RLP-Amide Band Z-RLP with peak purities. The forced degradation tests demonstrate that the peak of RP-HPLC is spectroscopically pure in all stressed conditions. All degradation products are separated from the main peak and do not interfere with main substance. This exploration not only augments the comprehension of RLP’s stability profile but also underscores the pivotal role of analytical techniques in upholding the safety and efficacy benchmarks of pharmaceutical formulations.
{"title":"Analysis of Forced Degradation Products in Rilpivirine using RP-HPLC and Peak Purity Evaluation","authors":"Abburi Ramarao, Guttikonda Venkata Rao, S. Chinnamaneni, Komati Navya Sri, Mandava Bhagya Tej, Gollammudi Padma Rao, V. Abbaraju, Mandava Venkata Basaveswarao RaoBasaveswarao Rao","doi":"10.13005/ojc/390613","DOIUrl":"https://doi.org/10.13005/ojc/390613","url":null,"abstract":"The primary objective of this research was to delve into the forced degradation products of Rilpivirine hydrochloride (RLP HCl), a crucial non-nucleoside reverse transcriptase inhibitor employed inmanagement of epidemic disease named HIV-1. The investigation utilised the probable of RP-HPLC in tandem with peak purity assessment .In order to simulate conceivable degradation pathways, the study encompassed a gamut of stress conditions like acidic, alkaline, oxidative , thermal and photolytic environments. Authors used Agilent zorbaxEclipse XDB C18 column (150x2.1mm, 1.8µm), RLP and impurities were separated. Buffer as pH of 3.0 and acetonitrile in gradient mode (68:32v/v), flow rate of 0.55ml/min. Volume injected is 3µL and detection wavelength is 220 nm. Temperature is maintained at 55oC by 70:30v/v mixture of water and acetonitrile.System suitability was erect to be within the limits. The average percentage recoveries for impurities were 98% to 101%.The outcomes of this meticulous study unveiled the susceptibilities of RLP to a spectrum of stress factors, in the generation of impurity profile RLP-Amide A, RLP-Amide Band Z-RLP with peak purities. The forced degradation tests demonstrate that the peak of RP-HPLC is spectroscopically pure in all stressed conditions. All degradation products are separated from the main peak and do not interfere with main substance. This exploration not only augments the comprehension of RLP’s stability profile but also underscores the pivotal role of analytical techniques in upholding the safety and efficacy benchmarks of pharmaceutical formulations.","PeriodicalId":19599,"journal":{"name":"Oriental Journal Of Chemistry","volume":"50 2","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139153687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Biofilm formation has incredible detrimental effects and has brought huge issue to our daily life. Pseudomonas aeruginosa is recognized as an opportunistic pathogen and its one of the antibiotic resistance mechanisms includes biofilm formation. To survive against harsh environmental conditions the microorganisms form an extracellular polymeric substance matrix. Natural products, particularly, marine natural products have been established useful in providing new chemical entities to mark biofilm inhibition and dole out as a rich source of privileged frames for studying chemical as well as biological applications. In the present study, antibiofilm potential of bioextract from Actinokineospora cibodasensis (MW513387) is tested against Pseudomonas aeruginosa (ATCC 27853) biofilm. The analysis of the quorum sensing modulation was done using exopolysaccharide (EPS) quantification and Cytotoxicity assays were performed to check toxicity. Scanning electron microscopy (SEM) was also conducted to visualize the mitigation of biofilm using the biocontrol agent. All the assays conducted evidently indicated that the potential bioactive compound from Actinokineospora cibodasensis has greater inhibition effect against pathogenic biofilm. In the near-term years it is expected that these pharmaceutical compounds from natural source be translated into antibiofilm drugs.
{"title":"Structural and Functional Dynamics of Secondary Metabolite from Actinokineospora cibodasensis against Pseudomonas aeruginosa Biofilm","authors":"Sreelakshmi K.S, U. R","doi":"10.13005/ojc/390619","DOIUrl":"https://doi.org/10.13005/ojc/390619","url":null,"abstract":"Biofilm formation has incredible detrimental effects and has brought huge issue to our daily life. Pseudomonas aeruginosa is recognized as an opportunistic pathogen and its one of the antibiotic resistance mechanisms includes biofilm formation. To survive against harsh environmental conditions the microorganisms form an extracellular polymeric substance matrix. Natural products, particularly, marine natural products have been established useful in providing new chemical entities to mark biofilm inhibition and dole out as a rich source of privileged frames for studying chemical as well as biological applications. In the present study, antibiofilm potential of bioextract from Actinokineospora cibodasensis (MW513387) is tested against Pseudomonas aeruginosa (ATCC 27853) biofilm. The analysis of the quorum sensing modulation was done using exopolysaccharide (EPS) quantification and Cytotoxicity assays were performed to check toxicity. Scanning electron microscopy (SEM) was also conducted to visualize the mitigation of biofilm using the biocontrol agent. All the assays conducted evidently indicated that the potential bioactive compound from Actinokineospora cibodasensis has greater inhibition effect against pathogenic biofilm. In the near-term years it is expected that these pharmaceutical compounds from natural source be translated into antibiofilm drugs.","PeriodicalId":19599,"journal":{"name":"Oriental Journal Of Chemistry","volume":"21 8","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139153345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In the course of this research, we successfully created three series of liquid crystalline compounds featuring the trans-cyclohexane structure. One series of compounds featured a double bond at the terminal position of the molecules, whereas the remaining two series incorporated disiloxane and trisiloxane groups. Each series comprised five spacers of different lengths, specifically 3, 4, 5, 6, and 11 methylene units. We identified the structures of the synthesized compounds using Nuclear Magnetic Resonance spectroscopy and characterized their liquid crystalline behavior through thermal analysis and polarized optical microscopy. The results revealed that both the length of the spacer and the presence of siloxane groups significantly influenced the liquid crystal phase transitions, transition temperatures, and temperature ranges. These findings provide valuable insights for designing and developing new liquid crystal materials with tailored properties for various applications.
{"title":"Preparation and Characterization of Organosiloxanes with A Liquid Crystalline Trans-4-Pentylcyclohexanoate Moiety","authors":"Li-Chuan Wu, Chih-Hung Lin","doi":"10.13005/ojc/390601","DOIUrl":"https://doi.org/10.13005/ojc/390601","url":null,"abstract":"In the course of this research, we successfully created three series of liquid crystalline compounds featuring the trans-cyclohexane structure. One series of compounds featured a double bond at the terminal position of the molecules, whereas the remaining two series incorporated disiloxane and trisiloxane groups. Each series comprised five spacers of different lengths, specifically 3, 4, 5, 6, and 11 methylene units. We identified the structures of the synthesized compounds using Nuclear Magnetic Resonance spectroscopy and characterized their liquid crystalline behavior through thermal analysis and polarized optical microscopy. The results revealed that both the length of the spacer and the presence of siloxane groups significantly influenced the liquid crystal phase transitions, transition temperatures, and temperature ranges. These findings provide valuable insights for designing and developing new liquid crystal materials with tailored properties for various applications.","PeriodicalId":19599,"journal":{"name":"Oriental Journal Of Chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139153179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abida Ash Mohd, Mohd Imran, Noura Yousif Alnaser, Shams Saud Altimyat, Nawaf M. Al-Otaibi, A. Bawadekji
This research aimed to discover novel isoniazid (INH) derivatives as anti-tubercular (anti-TB) agents. The chemical structures of isoniazid-based pyridazinone (IBP) derivatives were designed, and their toxicity and pharmacokinetic properties were predicted using the ProTox II and Swiss-ADME databases. The molecular docking of non-toxic IBPs was also performed concerning INH, pyrazinamide (PYZ), ethionamide (ETH), macozinone (MCZ), and BTZ043 utilizing DprE1 enzyme’s proteins (PDB IDs: 4F4Q, 4NCR and 6HEZ). Based on the in silico study results, IBP19, IBP21, IBP22, and IBP29 were selected for their synthesis, and the spectral analysis confirmed their chemical structures. In vitro, anti-TB activity against Mtb H37Rv strain and MTT assay (against HepG2 and Vero cell lines) of IBP19, IBP21, IBP22, and IBP29 were also carried out. A total of eleven non-toxic IBPs were identified with promising pharmacokinetic parameters. The docking score (DS in kcal/mol against 6HEZ protein) of IBP19 (-9.52), IBP21 (-8.78), IBP22 (-9.07), and IBP29 (-9.99) was better than MCZ (-8.76) and BTZ043 (-8.56) revealing their DprE1 enzyme inhibitory action. The in vitro anti-TB activity evaluation (MIC values) confirmed that IBP19 (1.562 µg/ml), IBP21 (1.562 µg/ml), IBP22 (1.562 µg/ml), and IBP29 (1.562 µg/ml) had almost double potency than INH (3.125 µg/ml), and PYZ (3.125 µg/ml). IBP19, IBP21, IBP22, and IBP29 also displayed a CC50 value of > 300 µg/ml against HCL and VCL cell lines. This effect was better than INH (> 200 µg/ml), ETH (> 150 µg/ml), and PYZ (> 200 µg/ml). Accordingly, IBP19, IBP21, IBP22, and IBP29 provide a new template for developing safe and effective novel DprE1 inhibitors.
{"title":"Discovery of New Isoniazid Derivatives As Anti-tubercular Agents: In silico Studies, Synthesis, and In vitro Activity Evaluation","authors":"Abida Ash Mohd, Mohd Imran, Noura Yousif Alnaser, Shams Saud Altimyat, Nawaf M. Al-Otaibi, A. Bawadekji","doi":"10.13005/ojc/390610","DOIUrl":"https://doi.org/10.13005/ojc/390610","url":null,"abstract":"This research aimed to discover novel isoniazid (INH) derivatives as anti-tubercular (anti-TB) agents. The chemical structures of isoniazid-based pyridazinone (IBP) derivatives were designed, and their toxicity and pharmacokinetic properties were predicted using the ProTox II and Swiss-ADME databases. The molecular docking of non-toxic IBPs was also performed concerning INH, pyrazinamide (PYZ), ethionamide (ETH), macozinone (MCZ), and BTZ043 utilizing DprE1 enzyme’s proteins (PDB IDs: 4F4Q, 4NCR and 6HEZ). Based on the in silico study results, IBP19, IBP21, IBP22, and IBP29 were selected for their synthesis, and the spectral analysis confirmed their chemical structures. In vitro, anti-TB activity against Mtb H37Rv strain and MTT assay (against HepG2 and Vero cell lines) of IBP19, IBP21, IBP22, and IBP29 were also carried out. A total of eleven non-toxic IBPs were identified with promising pharmacokinetic parameters. The docking score (DS in kcal/mol against 6HEZ protein) of IBP19 (-9.52), IBP21 (-8.78), IBP22 (-9.07), and IBP29 (-9.99) was better than MCZ (-8.76) and BTZ043 (-8.56) revealing their DprE1 enzyme inhibitory action. The in vitro anti-TB activity evaluation (MIC values) confirmed that IBP19 (1.562 µg/ml), IBP21 (1.562 µg/ml), IBP22 (1.562 µg/ml), and IBP29 (1.562 µg/ml) had almost double potency than INH (3.125 µg/ml), and PYZ (3.125 µg/ml). IBP19, IBP21, IBP22, and IBP29 also displayed a CC50 value of > 300 µg/ml against HCL and VCL cell lines. This effect was better than INH (> 200 µg/ml), ETH (> 150 µg/ml), and PYZ (> 200 µg/ml). Accordingly, IBP19, IBP21, IBP22, and IBP29 provide a new template for developing safe and effective novel DprE1 inhibitors.","PeriodicalId":19599,"journal":{"name":"Oriental Journal Of Chemistry","volume":"33 10","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139153332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In this research, thin films of ZnO doped with Sn were prepared through the sol-gel method. The effects of Sn dopant on optical, morphological and structural studies were investigated. All of the films in this work showed favored orientation along the (002) plane, according to XRD analysis. It was observed by SEM analysis that the study Sn morphological and structural studies were investigated. From AFM pictures it is clear that as the doping concentration rises, the size of the grains on the surface of thin films decreases.The existence of Zn, O and Sn was verified by the EDAX analysis. The Ultraviolet-visible spectroscope was utilized to examine the optical characteristics. That band gap increased with the dopant material percent increased.
{"title":"Effect of Sn-incorporation on the Structural and Optical Properties of ZnO Thin Films Prepared by Sol-Gel Method","authors":"Hansraj Sharma, Sunil Kumar, Jagavendra Yadav, Jagdish Prasad, Mangej Singh","doi":"10.13005/ojc/390614","DOIUrl":"https://doi.org/10.13005/ojc/390614","url":null,"abstract":"In this research, thin films of ZnO doped with Sn were prepared through the sol-gel method. The effects of Sn dopant on optical, morphological and structural studies were investigated. All of the films in this work showed favored orientation along the (002) plane, according to XRD analysis. It was observed by SEM analysis that the study Sn morphological and structural studies were investigated. From AFM pictures it is clear that as the doping concentration rises, the size of the grains on the surface of thin films decreases.The existence of Zn, O and Sn was verified by the EDAX analysis. The Ultraviolet-visible spectroscope was utilized to examine the optical characteristics. That band gap increased with the dopant material percent increased.","PeriodicalId":19599,"journal":{"name":"Oriental Journal Of Chemistry","volume":"1 2","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139153625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Manganese-doped cadmium sulfide quantum dots (QDs), co-doped with nitrogen, were synthesized using the chemical co-precipitation method (CPM). Surfactant 2-mercaptoethanol (ME) was used to efficiently regulate the size of these QDs. X-ray diffraction (XRD) analyses verified that the particles fell within the nano-dimension, measuring between 1-2 nm. A Rietveld analysis with X’pert high score software (XPHS) proved that these synthesized QDs contained many phases. The energy dispersive X-ray spectroscopy (EDX) technique confirmed the successful incorporation of both manganese and nitrogen dopants into the CdS. Ultraviolet-visible analysis (UV-Vis) demonstrated a noticeable shift towards the blue end in the energy gap, indicating the presence of a quantum-confinement effect. The photoluminescence (PL) investigations revealed a significant emission peak at λ = 634 nm, linked to the transition from 4T1 to 6A1, attributed to the incorporation of Mn2+ within the CdS core. Electron paramagnetic spectroscopy (EPR) demonstrated paramagnetic characteristics. EPR assessments of the g factor (1.995) and hyperfine splitting constant (A) values (7 mT) verified the existence of nitrogen and manganese ions in the tetrahedral positions of the CdS core. The notable alterations noticed in the magnetic and optical characteristics of the fabricated quantum dots imply promising uses in optoelectronic and magneto-luminescent applications.
{"title":"Adaptive Paramagnetism and Photoluminescence in Nitrogen Co-doped Mn: CdS Composite Quantum Dots","authors":"Surya Sekhar Reddy M, Kishore Kumar Y B","doi":"10.13005//ojc/390603","DOIUrl":"https://doi.org/10.13005//ojc/390603","url":null,"abstract":"Manganese-doped cadmium sulfide quantum dots (QDs), co-doped with nitrogen, were synthesized using the chemical co-precipitation method (CPM). Surfactant 2-mercaptoethanol (ME) was used to efficiently regulate the size of these QDs. X-ray diffraction (XRD) analyses verified that the particles fell within the nano-dimension, measuring between 1-2 nm. A Rietveld analysis with X’pert high score software (XPHS) proved that these synthesized QDs contained many phases. The energy dispersive X-ray spectroscopy (EDX) technique confirmed the successful incorporation of both manganese and nitrogen dopants into the CdS. Ultraviolet-visible analysis (UV-Vis) demonstrated a noticeable shift towards the blue end in the energy gap, indicating the presence of a quantum-confinement effect. The photoluminescence (PL) investigations revealed a significant emission peak at λ = 634 nm, linked to the transition from 4T1 to 6A1, attributed to the incorporation of Mn2+ within the CdS core. Electron paramagnetic spectroscopy (EPR) demonstrated paramagnetic characteristics. EPR assessments of the g factor (1.995) and hyperfine splitting constant (A) values (7 mT) verified the existence of nitrogen and manganese ions in the tetrahedral positions of the CdS core. The notable alterations noticed in the magnetic and optical characteristics of the fabricated quantum dots imply promising uses in optoelectronic and magneto-luminescent applications.","PeriodicalId":19599,"journal":{"name":"Oriental Journal Of Chemistry","volume":"57 2","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139154329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Novel hydrazone ligands (HL) derived from 2,5-hexandione and benzoyl hydrazine (HDBH), 2-furoyl hydrazine (HDFH), or 2-picolinoyl hydrazine (HDPH) were used to synthesize mononuclear Mn(II), Co(II), Ni(II), Cu(II), and Zn(II) complexes of the general formula [M(L)2].xH2O (x= 0-3). The hydrazone ligands and the isolated complexes were characterized by, spectral, thermal analysis, molar conductance, and magnetic moment measurements. Beside, density functional theory (DFT) computations have been to study structures and energetic of the ligand and its complexes. The IR spectral information suggests that the ligands exhibit monobasic tridentate behavior through their ONO donor atoms. The metal complexes were determined to possess monomeric octahedral geometry. The DPPH antioxidant capability of both the ligand and their metal complexes was evaluated.
{"title":"Synthesis, Characterization, Density Functional Theory Studies and Antioxidant Activity of Novel Hydrazone Ligands and their Metal Complexes","authors":"V. Suleman, Abdul Ghany Mohammed Al-Daher","doi":"10.13005/ojc/390624","DOIUrl":"https://doi.org/10.13005/ojc/390624","url":null,"abstract":"Novel hydrazone ligands (HL) derived from 2,5-hexandione and benzoyl hydrazine (HDBH), 2-furoyl hydrazine (HDFH), or 2-picolinoyl hydrazine (HDPH) were used to synthesize mononuclear Mn(II), Co(II), Ni(II), Cu(II), and Zn(II) complexes of the general formula [M(L)2].xH2O (x= 0-3). The hydrazone ligands and the isolated complexes were characterized by, spectral, thermal analysis, molar conductance, and magnetic moment measurements. Beside, density functional theory (DFT) computations have been to study structures and energetic of the ligand and its complexes. The IR spectral information suggests that the ligands exhibit monobasic tridentate behavior through their ONO donor atoms. The metal complexes were determined to possess monomeric octahedral geometry. The DPPH antioxidant capability of both the ligand and their metal complexes was evaluated.","PeriodicalId":19599,"journal":{"name":"Oriental Journal Of Chemistry","volume":"21 3","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139153369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vandana Kachhwaha, Pooja Kumari, Naresh Giri, P. Mishra
This study introduces an innovative method of using activated carbon derived from orange peels incorporated into calcium alginate beads to remove lead from synthetic water efficiently. This novel approach demonstrates remarkable effectiveness in addressing lead pollution in water. Established techniques such as SEM and FTIR were employed to characterize the adsorbents created in the laboratories. Batch studies confirmed the lead adsorbed were conducted to evaluate the efficiency of lead removal, with the highest removal efficiencies achieved at pH 6.5 (90.3%), an adsorbent dose of 2 mg (90.3%), a contact time of 50 minutes (92.3%), and an initial lead solution concentration of 20 ppm (93.2%). The study employed various adsorption models, including Langmuir, Freundlich, and Tempkin models. The Langmuir model exhibited an excellent fit to the adsorption isotherm at 60 °C, as indicated by a high linear regression correlation coefficient. For the bioadsorption process, pseudo-second-order kinetics fits well (R2 = 0.9992). The analytical results verify that activated carbon from discarded orange peels and calcium alginate beads effectively removes Pb, offering an encouraging solution for water purification challenges.
{"title":"Evaluation of Lead Removal by Activated Citrus Sinensis Biochar Impregnated with Calcium Alginate Beads","authors":"Vandana Kachhwaha, Pooja Kumari, Naresh Giri, P. Mishra","doi":"10.13005/ojc/390615","DOIUrl":"https://doi.org/10.13005/ojc/390615","url":null,"abstract":"This study introduces an innovative method of using activated carbon derived from orange peels incorporated into calcium alginate beads to remove lead from synthetic water efficiently. This novel approach demonstrates remarkable effectiveness in addressing lead pollution in water. Established techniques such as SEM and FTIR were employed to characterize the adsorbents created in the laboratories. Batch studies confirmed the lead adsorbed were conducted to evaluate the efficiency of lead removal, with the highest removal efficiencies achieved at pH 6.5 (90.3%), an adsorbent dose of 2 mg (90.3%), a contact time of 50 minutes (92.3%), and an initial lead solution concentration of 20 ppm (93.2%). The study employed various adsorption models, including Langmuir, Freundlich, and Tempkin models. The Langmuir model exhibited an excellent fit to the adsorption isotherm at 60 °C, as indicated by a high linear regression correlation coefficient. For the bioadsorption process, pseudo-second-order kinetics fits well (R2 = 0.9992). The analytical results verify that activated carbon from discarded orange peels and calcium alginate beads effectively removes Pb, offering an encouraging solution for water purification challenges.","PeriodicalId":19599,"journal":{"name":"Oriental Journal Of Chemistry","volume":"3 4","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139153483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rare earth elements (REEs) have versatile applications in various industries and are thrown as industrial waste waters, which leads to serious environmental issues.This paper describes the adsorption efficiency of nano copper ferrite on REEs namely lanthanum and cerium in their trivalent states at room temperature and at the optimum conditions of pH, contact time, adsorbent, adsorbate dosage,temperature etc. The batch adsorption studies were conducted for the adsorption studies using ICPAES (Inductive coupled plasma atomic emission spectro photometer). In addition the data is studied for Langmuir and Freundlich models and observed that data well fitted to Langmuir monolayer adsorption. From the graph and intercept values of theoretical and experimental values, the pseudo second order kinetics are followed. Thermodynamic parameters reveal that reaction is spontaneous and endothermic. From the over all observations like fast kinetics, chemical stability, high adsorption capacity it is concluded that nano CuFe 2 O 4 has maximum efficiency for the adsorption of REEs
{"title":"Efficient Adsorption of Trivalent Rare Earth Elements Using Nano Copper Ferrite: Kinetics, Isotherms and Thermodynamics","authors":"Sudha Thotakura","doi":"10.13005/ojc/390628","DOIUrl":"https://doi.org/10.13005/ojc/390628","url":null,"abstract":"Rare earth elements (REEs) have versatile applications in various industries and are thrown as industrial waste waters, which leads to serious environmental issues.This paper describes the adsorption efficiency of nano copper ferrite on REEs namely lanthanum and cerium in their trivalent states at room temperature and at the optimum conditions of pH, contact time, adsorbent, adsorbate dosage,temperature etc. The batch adsorption studies were conducted for the adsorption studies using ICPAES (Inductive coupled plasma atomic emission spectro photometer). In addition the data is studied for Langmuir and Freundlich models and observed that data well fitted to Langmuir monolayer adsorption. From the graph and intercept values of theoretical and experimental values, the pseudo second order kinetics are followed. Thermodynamic parameters reveal that reaction is spontaneous and endothermic. From the over all observations like fast kinetics, chemical stability, high adsorption capacity it is concluded that nano CuFe 2 O 4 has maximum efficiency for the adsorption of REEs","PeriodicalId":19599,"journal":{"name":"Oriental Journal Of Chemistry","volume":"2 4","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139153621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vegetable oils are often associated with well-known varieties like sunflower, olive, and corn. However, there are lesser-known options worth exploring to appreciate their distinct qualities. One such overlooked oil is cottonseed oil, derived from the Malvaceae cotton family plant. In a recent study, we delved into the rheological behavior of cottonseed oil. Similar to many vegetable oils, it exhibits a non-Newtonian behavior, making it a viable alternative to mineral oils. The rheological analysis was conducted using the Brookfield RVDV II I Ultra Rheometer, with shear rates incrementally increasing.
植物油通常与葵花籽油、橄榄油和玉米油等知名品种有关。然而，还有一些鲜为人知的选择值得我们去探索，以领略它们的独特品质。棉籽油就是这样一种被忽视的油，它提取自锦葵科棉花属植物。在最近的一项研究中，我们深入研究了棉籽油的流变行为。与许多植物油类似，棉籽油也表现出非牛顿特性，使其成为矿物油的可行替代品。流变分析使用 Brookfield RVDV II I 超流变仪进行，剪切速率逐渐增加。
{"title":"Rheology of Cottonseed (Gossypium hirsutum) Oil used as Biodegradable Lubricant","authors":"Ioana Stanciu","doi":"10.13005/ojc/390633","DOIUrl":"https://doi.org/10.13005/ojc/390633","url":null,"abstract":"Vegetable oils are often associated with well-known varieties like sunflower, olive, and corn. However, there are lesser-known options worth exploring to appreciate their distinct qualities. One such overlooked oil is cottonseed oil, derived from the Malvaceae cotton family plant. In a recent study, we delved into the rheological behavior of cottonseed oil. Similar to many vegetable oils, it exhibits a non-Newtonian behavior, making it a viable alternative to mineral oils. The rheological analysis was conducted using the Brookfield RVDV II I Ultra Rheometer, with shear rates incrementally increasing.","PeriodicalId":19599,"journal":{"name":"Oriental Journal Of Chemistry","volume":"159 5","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139153829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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