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Differences in Incidence of Preoperative Deep Vein Thrombosis and Coagulation Function at Admission in Younger and Older Adults With Hip Fracture. 老年髋部骨折患者术前深静脉血栓形成及入院时凝血功能的差异
IF 1.1 4区 医学 Q3 ORTHOPEDICS Pub Date : 2025-05-01 Epub Date: 2025-05-12 DOI: 10.3928/01477447-20250421-01
Li-Tao Shi, Rui Gu, Li-Juan Duan

Background: The objectives of this study were to analyze differences in deep vein thrombosis (DVT) incidence in both lower extremities before operation and blood coagulation function at admission in younger and older adults with hip fracture and to guide DVT prevention in these patients.

Materials and methods: The 505 hip fracture patients enrolled in this research were sorted into an older adult (≥60 years) group (424 cases) and a younger adult group (81 cases) based on age. Preoperative DVT incidence in both lower extremities was analyzed. Differences in demographic characteristics, comorbidities, and preoperative DVT incidence in both lower extremities, blood coagulation function, and platelet count at admission were compared.

Results: Preoperative DVT incidence in both lower extremities in hip fracture patients increased with age. Compared with the younger adult group, preoperative DVT incidence in both lower extremities was higher, the ratio of women was higher, the ratio of patients with comorbidities (eg, hypertension, diabetes) was higher, fibrinogen was higher, and antithrombin III was lower in the older adult group.

Conclusion: Preoperative DVT incidence in both lower extremities in these patients increased with age. Compared with the younger adult group, preoperative DVT incidence was higher, hypercoagulable state was more obvious, and anticoagulant activity was weaker in the older adult group. This may be related to more patients of advanced age, a higher ratio of female patients, and more comorbidities. Advanced age (≥60 years) is the independent risk factor for preoperative DVT. [Orthopedics. 2025;48(3):139-145.].

背景:本研究的目的是分析年轻和老年髋部骨折患者术前双下肢深静脉血栓形成(DVT)发生率和入院时凝血功能的差异,并指导这些患者预防DVT。材料与方法:本研究纳入505例髋部骨折患者,根据年龄分为老年人(≥60岁)组(424例)和年轻人组(81例)。分析术前双下肢深静脉血栓的发生率。比较人口学特征、合并症、术前双下肢DVT发生率、凝血功能和入院时血小板计数的差异。结果:髋部骨折患者术前双下肢DVT发生率随年龄增加而增加。与青壮年组相比,术前双下肢DVT发生率较高,女性比例较高,合并高血压、糖尿病等合并症比例较高,老年组纤维蛋白原较高,抗凝血酶III较低。结论:患者术前双下肢DVT发生率随年龄增加而增加。与青壮年组相比,老年组术前DVT发生率更高,高凝状态更明显,抗凝活性较弱。这可能与老年患者多、女性患者比例高、合并症多有关。高龄(≥60岁)是术前DVT发生的独立危险因素。[矫形手术。48 2025;(3): 139 - 145。]。
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引用次数: 0
Effectiveness of an All-arthroscopic Procedure for Terrible Triad Injuries at 5-Year Follow-up. 全关节镜手术治疗可怕三联征损伤的5年随访效果。
IF 1.1 4区 医学 Q3 ORTHOPEDICS Pub Date : 2025-05-01 Epub Date: 2025-03-31 DOI: 10.3928/01477447-20250319-02
Gyeong-Hoon Lim, Min-Su Joo, Sung-Hyun Lee, Hyung-Gyu Cho, Gi-Woong Sim, Jeong-Woo Kim

Background: This study evaluated the clinical and radiologic results of allarthroscopic treatment of terrible triad of the elbow over a minimum of 5 years.

Materials and methods: We retrospectively reviewed consecutive patients with terrible triad injury who underwent all-arthroscopic surgery between January 2011 and June 2018. We performed all-arthroscopic treatment for these patients, excluding those with a Regan-Morrey type III coronoid process fracture, involvement of the anteromedial facet, or a radial head fracture involving >50% of the articular surface. Elbow stability, range of motion, Mayo Elbow Performance Score, and radiologic outcomes were assessed at least 5 years postoperatively.

Results: Thirty-two patients met the inclusion criteria, and mean age was 49.5±15.9 years. At a mean follow-up of 6.9±1.8 years, mean arc of flexion for the affected elbow was 7.1°±7.4° to 132.4°±10.0°. Mean visual analog scale and Mayo Elbow Performance Score were 1.4±0.6 and 91±15.7 points, respectively. Clinical scores and range of motion showed no significant differences between the affected and contralateral elbows. Nonunion of the coronoid process occurred in 4 cases, but none led to instability or required reoperation. Heterotopic ossification was observed for 15 patients (47%), grade 1 arthritis for 7 patients (22%), and grade 3 arthritis for 3 patients (9%), but none progressed to joint stiffness or required reoperation. Two complications required reoperation: 1 case of pin site irritation that resolved after pin removal and 1 case of worsening arthritic degeneration leading to total elbow arthroplasty at 5-year follow-up. No other complications, such as infection or neurovascular injury, were observed.

Conclusion: In terrible triad elbow injuries, all-arthroscopic treatment restores elbow joint stability and achieves good clinical and radiologic outcomes compared with open treatment. We recommend this procedure as a treatment option for patients if the indications are met, such as Regan-Morrey type I or II coronoid process fractures and radial head fractures involving <50% of the articular surface. [Orthopedics. 2025;48(3):e131-e138.].

背景:本研究评估了至少5年来全关节镜治疗肘关节恐怖三联征的临床和放射学结果。材料和方法:我们回顾性分析了2011年1月至2018年6月期间连续接受全关节镜手术的可怕三联征损伤患者。我们对这些患者进行了全关节镜治疗,排除了Regan-Morrey III型冠突骨折、累及前内侧小面或桡骨头骨折累及约50%关节面患者。术后至少5年评估肘关节稳定性、活动范围、Mayo肘关节功能评分和影像学结果。结果:32例患者符合纳入标准,平均年龄49.5±15.9岁。在平均6.9±1.8年的随访中,受影响肘关节的平均屈曲弧度为7.1°±7.4°至132.4°±10.0°。平均视觉模拟评分为1.4±0.6分,Mayo肘关节功能评分为91±15.7分。临床评分和活动范围显示患侧和对侧肘部无显著差异。4例发生冠突不连,但均未导致不稳定或需要再次手术。异位骨化15例(47%),1级关节炎7例(22%),3级关节炎3例(9%),但没有进展到关节僵硬或需要再次手术。2例并发症需要再次手术:1例针部位刺激,在取出针后解决,1例关节炎恶化导致全肘关节置换术,随访5年。无其他并发症,如感染或神经血管损伤。结论:与开放治疗相比,全关节镜治疗可恢复肘关节稳定性,取得良好的临床和影像学结果。如果符合适应症,如Regan-Morrey I型或II型冠突骨折和涉及骨科的桡骨头骨折,我们建议将此手术作为治疗选择。[202x;4x(x):xx-xx]。
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引用次数: 0
Percutaneous Clamp-assisted Reduction Before Intramedullary Nailing for Tibial Shaft Fractures to Improve Reduction Outcomes: A Retrospective Cohort Study. 在髓内钉治疗胫骨干骨折前经皮钳辅助复位以提高复位效果:一项回顾性队列研究。
IF 1.1 4区 医学 Q3 ORTHOPEDICS Pub Date : 2025-05-01 Epub Date: 2025-05-12 DOI: 10.3928/01477447-20250422-01
Zhenglin Niu, Yue Lian, Haixiang Sun, Yongzhong Cheng, Zhongkai Wu, Changlong Shi

Background: This retrospective cohort study aimed to compare the clinical outcomes of percutaneous clamp-assisted reduction (PCR) and conventional direct reduction (DR) techniques prior to intramedullary nailing (IMN) in the management of tibial shaft fractures.

Materials and methods: The medical records of 68 consecutive patients treated via IMN via the infrapatellar approach between January 2020 and December 2023 were retrospectively reviewed. After the inclusion/exclusion criteria were applied, patients were divided into PCR (n=37) and DR (n=31) groups. Demographic data, fracture characteristics, surgical data, and prognostic outcomes were analyzed.

Results: Baseline characteristics showed no significant intergroup differences. PCR demonstrated a longer reduction time (25.3±1.9 min vs 21.4±1.4 min, P<0.01) but required less fluoroscopic exposure (18.0±1.4 vs 22.0±1.4, P<0.01), shorter surgical duration (73.0±3.1 min vs 88.7±8.6 min, P<0.01), and reduced blood loss (101.6±17.2 mL vs 153.2±52.9 mL, P<0.01). No open reductions occurred in the PCR group, whereas five cases occurred in the DR group (16.1%, P<0.05). Approximate anatomical union rates significantly favored PCR (62.2% vs 16.1%, P<0.01). No statistically significant differences were observed between the two groups in terms of American Orthopaedic Foot and Ankle Society score, union time, delayed union rate, or malunion rate.

Conclusion: Compared with conventional DR, PCR prior to IMN improves fracture reduction quality, reduces intraoperative invasiveness, and enhances procedural efficiency, with superior anatomical alignment outcomes. [Orthopedics. 2025;48(3):e147-e152.].

背景:本回顾性队列研究旨在比较经皮钳辅助复位(PCR)和常规直接复位(DR)技术在髓内钉(IMN)治疗胫骨干骨折的临床结果。材料与方法:回顾性分析2020年1月至2023年12月间经髌下入路IMN治疗的68例患者的病历。应用纳入/排除标准后,将患者分为PCR组(n=37)和DR组(n=31)。对人口统计资料、骨折特征、手术资料和预后结果进行分析。结果:基线特征组间无显著差异。PCR复位时间更长(25.3±1.9 min vs 21.4±1.4 min)。结论:与常规DR相比,在IMN前进行PCR可提高骨折复位质量,减少术中侵入性,提高手术效率,并具有更好的解剖定位效果。[矫形手术。2025; 48 (3): e147-e152。]。
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引用次数: 0
Treatment and Clinical Outcomes of Tibial Spine Fractures in Adults: A Systematic Review and Meta-Analysis. 成人胫骨骨折的治疗和临床结果:系统回顾和荟萃分析。
IF 1.1 4区 医学 Q3 ORTHOPEDICS Pub Date : 2025-05-01 Epub Date: 2025-04-23 DOI: 10.3928/01477447-20250415-01
Harmon S Khela, Monty S Khela, Jonathan Jose, Rashad Madi, John D Kelly, Liane Miller

Background: Adult tibial spine fractures (TSFs) are rare but can cause significant morbidity.

Materials and methods: A systematic review identified studies on adult TSFs. Patient demographics, fracture characteristics, surgical details, outcomes, and complications were analyzed using descriptive statistics and meta-analysis.

Results: Twenty-eight studies (691 cases) were included. Most fractures were type III, treated arthroscopically with sutures or screws. Fracture type showed no significant differences in outcomes. Suture fixation yielded better functional scores and fewer complications than screws.

Conclusion: No definitive advantage was observed for either fracture type or fixation method. Further research is needed to establish optimal treatments. [Orthopedics. 2025;48(3):174-187.].

背景:成人胫骨骨折(TSFs)是罕见的,但可引起显著的发病率。材料和方法:系统回顾了成人tsf的研究。采用描述性统计和荟萃分析对患者人口统计学、骨折特征、手术细节、结局和并发症进行分析。结果:纳入28项研究(691例)。大多数骨折为III型,采用关节镜下缝合或螺钉治疗。骨折类型无明显差异。与螺钉相比,缝合固定具有更好的功能评分和更少的并发症。结论:骨折类型和固定方法均无明确优势。需要进一步的研究来确定最佳的治疗方法。[矫形手术。48 2025;(3): 174 - 187。]。
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引用次数: 0
Periacetabular Osteotomy Leads to Improved Long-term Patient-reported Outcomes: A Systematic Review. 髋臼周围截骨术可改善患者报告的长期预后:一项系统综述。
IF 1.2 4区 医学 Q3 ORTHOPEDICS Pub Date : 2025-05-01 Epub Date: 2025-04-17 DOI: 10.3928/01477447-20250409-03
James S MacLeod, Justin R Zhu, Michael S Lee, Serkan Surucu, Jack Gagné, Seema M Patel, Trevan Klug, Nancy Park, Mackenzie Norman, Jay Moran, Andrew E Jimenez

Background: Periacetabular osteotomy (PAO) has shown favorable outcomes. The goal of this study was to conduct a systematic review to assess the reoperation rates and long-term patient-reported outcomes (PROs) of PAO for the treatment of hip dysplasia.

Materials and methods: A systematic review was conducted. Studies that reported PROs with a minimum mean of 10-year follow-up were included.

Results: The 8 studies (984 hips) that were included reported a significant improvement between preoperative and postoperative PROs.

Conclusion: Patients who underwent PAO surgery showed significant improvement in PROs at a minimum mean 10-year follow-up. [Orthopedics. 2025;48(3):e113-e123.].

背景:髋臼周围截骨术(PAO)显示出良好的结果。本研究的目的是进行一项系统评价,以评估PAO治疗髋关节发育不良的再手术率和长期患者报告的结果(PROs)。材料和方法:进行系统综述。报告PROs的研究平均随访时间至少为10年。结果:纳入的8项研究(984髋)报告了术前和术后PROs的显著改善。结论:接受PAO手术的患者在至少平均10年的随访中显示出pro的显著改善。[矫形手术。2025; 48 (3): e113-e123。]。
{"title":"Periacetabular Osteotomy Leads to Improved Long-term Patient-reported Outcomes: A Systematic Review.","authors":"James S MacLeod, Justin R Zhu, Michael S Lee, Serkan Surucu, Jack Gagné, Seema M Patel, Trevan Klug, Nancy Park, Mackenzie Norman, Jay Moran, Andrew E Jimenez","doi":"10.3928/01477447-20250409-03","DOIUrl":"10.3928/01477447-20250409-03","url":null,"abstract":"<p><strong>Background: </strong>Periacetabular osteotomy (PAO) has shown favorable outcomes. The goal of this study was to conduct a systematic review to assess the reoperation rates and long-term patient-reported outcomes (PROs) of PAO for the treatment of hip dysplasia.</p><p><strong>Materials and methods: </strong>A systematic review was conducted. Studies that reported PROs with a minimum mean of 10-year follow-up were included.</p><p><strong>Results: </strong>The 8 studies (984 hips) that were included reported a significant improvement between preoperative and postoperative PROs.</p><p><strong>Conclusion: </strong>Patients who underwent PAO surgery showed significant improvement in PROs at a minimum mean 10-year follow-up. [<i>Orthopedics.</i> 2025;48(3):e113-e123.].</p>","PeriodicalId":19631,"journal":{"name":"Orthopedics","volume":"48 3","pages":"e113-e123"},"PeriodicalIF":1.2,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144008446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epidemiology of Shoulder Injuries Presenting to US Emergency Departments. 美国急诊科肩部损伤的流行病学
IF 1.1 4区 医学 Q3 ORTHOPEDICS Pub Date : 2025-03-01 Epub Date: 2025-02-11 DOI: 10.3928/01477447-20250204-03
Timothy A Reiad, Emilio Peveri, Peter V Dinh, Brett D Owens

Background: Shoulder injuries are a significant cause of musculoskeletal complaints in emergency departments (EDs), but data on these injuries in the United States are limited. This study analyzed shoulder injuries reported to US EDs from 2006 to 2016, focusing on trends in injury mechanisms, diagnoses, and demographics.

Materials and methods: Data from the National Electronic Injury Surveillance System (NEISS) database were used to analyze 6,689,422 shoulder injuries reported to US EDs during 11 years, examining injury rates, causes, diagnoses, and demographics.

Results: An estimated 6,689,422 shoulder injuries were reported during the study period, accounting for 4.35% of all injuries reported to US EDs. The highest injury rate was observed in individuals 15 to 24 years (3.15 per 1000 US population), while children younger than 5 years had the lowest rate (0.97 per 1000). The most common causes of injury were sports and recreation (45.84%), home structure (20.79%), and home furniture (18.91%). The most frequent diagnoses included fractures (20.30%), contusions (18.23%), and dislocations (12.92%). More than one-third of the injuries (39.2%) occurred at home. Injury rates decreased for individuals younger than 25 years but increased for those 45 to 64 years during the study period. Younger individuals and males showed greater sport-related injuries, while older populations and females more commonly presented with home-related injuries.

Conclusion: This study revealed unique demographic patterns in the causes and mechanisms of shoulder injuries. These findings suggest that tailored prevention strategies could be particularly effective, helping to improve both injury prevention efforts and the clinical care of patients with shoulder injuries. [Orthopedics. 2025;48(2):e81-e87.].

背景:肩部损伤是急诊科(EDs)肌肉骨骼疾病主诉的一个重要原因,但在美国有关这些损伤的数据有限。本研究分析了2006年至2016年美国急诊科报告的肩部损伤,重点关注损伤机制、诊断和人口统计学的趋势。材料和方法:来自国家电子损伤监测系统(NEISS)数据库的数据用于分析11年来美国急诊科报告的6,689,422例肩部损伤,检查损伤率、原因、诊断和人口统计学。结果:在研究期间,估计有6,689,422例肩部损伤报告,占美国急诊科报告的所有损伤的4.35%。伤害率最高的是15至24岁的个体(每1000名美国人口中有3.15人),而5岁以下的儿童的伤害率最低(每1000人中有0.97人)。最常见的伤害原因是运动和娱乐(45.84%)、家居结构(20.79%)和家居家具(18.91%)。最常见的诊断包括骨折(20.30%)、挫伤(18.23%)和脱位(12.92%)。超过三分之一(39.2%)的伤害发生在家中。在研究期间,25岁以下的人受伤率下降,但45岁至64岁的人受伤率上升。年轻人和男性表现出更多的运动相关损伤,而老年人和女性更常见的是家庭相关损伤。结论:这项研究揭示了肩部损伤的原因和机制的独特人口统计学模式。这些发现表明,量身定制的预防策略可能特别有效,有助于改善损伤预防工作和肩伤患者的临床护理。[矫形手术。202 x; 4 x (x): xx-xx。]。
{"title":"Epidemiology of Shoulder Injuries Presenting to US Emergency Departments.","authors":"Timothy A Reiad, Emilio Peveri, Peter V Dinh, Brett D Owens","doi":"10.3928/01477447-20250204-03","DOIUrl":"10.3928/01477447-20250204-03","url":null,"abstract":"<p><strong>Background: </strong>Shoulder injuries are a significant cause of musculoskeletal complaints in emergency departments (EDs), but data on these injuries in the United States are limited. This study analyzed shoulder injuries reported to US EDs from 2006 to 2016, focusing on trends in injury mechanisms, diagnoses, and demographics.</p><p><strong>Materials and methods: </strong>Data from the National Electronic Injury Surveillance System (NEISS) database were used to analyze 6,689,422 shoulder injuries reported to US EDs during 11 years, examining injury rates, causes, diagnoses, and demographics.</p><p><strong>Results: </strong>An estimated 6,689,422 shoulder injuries were reported during the study period, accounting for 4.35% of all injuries reported to US EDs. The highest injury rate was observed in individuals 15 to 24 years (3.15 per 1000 US population), while children younger than 5 years had the lowest rate (0.97 per 1000). The most common causes of injury were sports and recreation (45.84%), home structure (20.79%), and home furniture (18.91%). The most frequent diagnoses included fractures (20.30%), contusions (18.23%), and dislocations (12.92%). More than one-third of the injuries (39.2%) occurred at home. Injury rates decreased for individuals younger than 25 years but increased for those 45 to 64 years during the study period. Younger individuals and males showed greater sport-related injuries, while older populations and females more commonly presented with home-related injuries.</p><p><strong>Conclusion: </strong>This study revealed unique demographic patterns in the causes and mechanisms of shoulder injuries. These findings suggest that tailored prevention strategies could be particularly effective, helping to improve both injury prevention efforts and the clinical care of patients with shoulder injuries. [<i>Orthopedics</i>. 2025;48(2):e81-e87.].</p>","PeriodicalId":19631,"journal":{"name":"Orthopedics","volume":" ","pages":"e81-e87"},"PeriodicalIF":1.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143399645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Orthopedic Patients Are Highly Amenable to Cannabis-Based Products for the Treatment of Musculoskeletal Pain. 骨科患者对以大麻为基础的产品治疗肌肉骨骼疼痛非常敏感。
IF 1.1 4区 医学 Q3 ORTHOPEDICS Pub Date : 2025-03-01 Epub Date: 2025-01-17 DOI: 10.3928/01477447-20250114-02
William J Karakash, Ioanna K Bolia, Brandon A Levian, Timothy N Chu, Daniel R Kim, Amir Fathi, Joseph N Liu, Frank A Petrigliano, Alexander E Weber

Background: Tetrahydrocannabinol (THC)-based and cannabidiol (CBD)-based products are increasing in popularity for the management of pain. Cannabis-based products may serve as a valuable alternative to traditional analgesics such as opioids for pain management among orthopedic patients. The purpose of this study was to investigate the perspective of orthopedic sports medicine patients regarding the use of THC- and CBD-based products for the management of musculoskeletal pain.

Materials and methods: A short, 11-question survey was distributed to orthopedic sports medicine patients in clinic and via email. Survey participation was voluntary. Retrospective chart review was conducted for participating patients to collect additional data such as visit diagnosis.

Results: A total of 182 patients completed the survey. Most were familiar or somewhat familiar with THC (61%) and CBD (63.2%) products and their use for musculoskeletal pain. Of the patients, 53.3% were aware of friends and family currently using CBD products to help manage musculoskeletal pain. Of the patients, 81.3% were amenable to receiving THC-based products and 90.1% were amenable to receiving CBD-based products for the management of their musculoskeletal pain. The patients were statistically more amenable to receiving CBD-based products than THC-based products (P=.017). Among the patients, 85.3% believed cannabis-based products would help in the fight against the opioid epidemic.

Conclusion: Orthopedic patients are aware of THC- and CBD-based products, and the majority are willing to receive these products to help manage their musculoskeletal pain and orthopedic-related issues. Orthopedic surgeons should be aware of the increasing popularity of CBD-based products and educate themselves and their patients regarding the appropriate use of them. [Orthopedics. 2025;48(2):98-103.].

背景:基于四氢大麻酚(THC)和基于大麻二酚(CBD)的产品在疼痛管理中越来越受欢迎。以大麻为基础的产品可以作为传统止痛药(如阿片类药物)的有价值的替代品,用于骨科患者的疼痛管理。本研究的目的是调查骨科运动医学患者对使用四氢大麻酚和cbd为基础的产品来治疗肌肉骨骼疼痛的看法。材料与方法:对骨科运动医学患者进行问卷调查,问卷共11个问题。调查的参与是自愿的。对参与研究的患者进行回顾性图表回顾,收集诸如就诊诊断等附加数据。结果:共182例患者完成调查。大多数人熟悉或有点熟悉四氢大麻酚(61%)和CBD(63.2%)产品及其用于肌肉骨骼疼痛。在患者中,53.3%的人知道朋友和家人目前使用CBD产品来帮助控制肌肉骨骼疼痛。在患者中,81.3%的人接受基于thc的产品,90.1%的人接受基于cbd的产品来治疗肌肉骨骼疼痛。患者接受基于cbd的产品比基于thc的产品更具统计学意义(P= 0.017)。在患者中,85.3%的人认为大麻产品有助于对抗阿片类药物的流行。结论:骨科患者了解四氢大麻酚和大麻二酚类产品,并且大多数患者愿意接受这些产品来帮助管理他们的肌肉骨骼疼痛和骨科相关问题。骨科医生应该意识到基于cbd的产品越来越受欢迎,并教育自己和患者如何正确使用它们。[矫形手术。202 x; 4 x (x): xx-xx。]。
{"title":"Orthopedic Patients Are Highly Amenable to Cannabis-Based Products for the Treatment of Musculoskeletal Pain.","authors":"William J Karakash, Ioanna K Bolia, Brandon A Levian, Timothy N Chu, Daniel R Kim, Amir Fathi, Joseph N Liu, Frank A Petrigliano, Alexander E Weber","doi":"10.3928/01477447-20250114-02","DOIUrl":"10.3928/01477447-20250114-02","url":null,"abstract":"<p><strong>Background: </strong>Tetrahydrocannabinol (THC)-based and cannabidiol (CBD)-based products are increasing in popularity for the management of pain. Cannabis-based products may serve as a valuable alternative to traditional analgesics such as opioids for pain management among orthopedic patients. The purpose of this study was to investigate the perspective of orthopedic sports medicine patients regarding the use of THC- and CBD-based products for the management of musculoskeletal pain.</p><p><strong>Materials and methods: </strong>A short, 11-question survey was distributed to orthopedic sports medicine patients in clinic and via email. Survey participation was voluntary. Retrospective chart review was conducted for participating patients to collect additional data such as visit diagnosis.</p><p><strong>Results: </strong>A total of 182 patients completed the survey. Most were familiar or somewhat familiar with THC (61%) and CBD (63.2%) products and their use for musculoskeletal pain. Of the patients, 53.3% were aware of friends and family currently using CBD products to help manage musculoskeletal pain. Of the patients, 81.3% were amenable to receiving THC-based products and 90.1% were amenable to receiving CBD-based products for the management of their musculoskeletal pain. The patients were statistically more amenable to receiving CBD-based products than THC-based products (<i>P</i>=.017). Among the patients, 85.3% believed cannabis-based products would help in the fight against the opioid epidemic.</p><p><strong>Conclusion: </strong>Orthopedic patients are aware of THC- and CBD-based products, and the majority are willing to receive these products to help manage their musculoskeletal pain and orthopedic-related issues. Orthopedic surgeons should be aware of the increasing popularity of CBD-based products and educate themselves and their patients regarding the appropriate use of them. [<i>Orthopedics</i>. 2025;48(2):98-103.].</p>","PeriodicalId":19631,"journal":{"name":"Orthopedics","volume":" ","pages":"98-103"},"PeriodicalIF":1.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143009235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Direct Anterior Approach "No Trial Reduction Technique" in Bipolar Hemiarthroplasty for Treatment of Osteoporotic Femoral Neck Fracture: Surgical Techniques and Case Series. 双极半关节置换术治疗骨质疏松性股骨颈骨折的直接前路“无试验复位技术”:手术技术和病例系列。
IF 1.1 4区 医学 Q3 ORTHOPEDICS Pub Date : 2025-03-01 Epub Date: 2024-12-03 DOI: 10.3928/01477447-20241127-01
Chatchapol Ongkosit, Weerachai Kosuwon

Bipolar hemiarthroplasty (BHA) for osteoporotic femoral neck fractures has a risk of proximal femoral fracture during trials, especially with larger trial bipolar shells. This study introduces a novel technique for BHA via the direct anterior approach, aiming to reduce trial use and lower the risk of iatrogenic femoral fractures. The "no trial reduction technique" involves positioning only the trial neck segment against the acetabulum's me-dial wall, without the bipolar shell and trial head. Fluoros-copy measures limb length differences to determine optimal femoral head and bipolar shell thickness, resulting in comparable limb lengths without early complications. [Orthopedics. 2025;48(2):74-78.].

双极半关节置换术(BHA)治疗骨质疏松性股骨颈骨折在试验期间有股骨近端骨折的风险,特别是双极外壳较大的试验。本研究介绍了一种通过直接前路入路治疗BHA的新技术,旨在减少试验使用并降低医源性股骨骨折的风险。“无试验复位技术”包括仅将试验颈段靠在髋臼内侧壁上,不包括双极骨壳和试验头。x线检查测量肢体长度差异,以确定最佳股骨头和双极壳厚度,从而产生可比较的肢体长度,无早期并发症。[矫形手术。202 x; 4 x (x): xx-xx。]。
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引用次数: 0
The Fragility of Statistical Findings Regarding Hemiarthroplasty Versus Total Hip Arthroplasty for Displaced Femoral Neck Fractures. 股骨颈移位骨折半髋关节置换术与全髋关节置换术统计结果的脆弱性。
IF 1.1 4区 医学 Q3 ORTHOPEDICS Pub Date : 2025-03-01 Epub Date: 2025-02-11 DOI: 10.3928/01477447-20250206-02
Alec M Giakas, Alexandra L Hohmann, Nikhil N Mehta, Julia M Dambly, Jess H Lonner

There is debate over the treatment of displaced femoral neck fractures with either hemiarthroplasty or total hip arthroplasty. This study aimed to evaluate the fragility index (FI) of randomized controlled trials (RCTs) comparing these methods. We queried for these RCTs containing dichotomous outcomes, finding 11 RCTs with 63 dichotomous outcomes. The median FI for all outcomes was 6, signifying that 6 event reversals would change the statistical significance of an outcome. The median FI was 2 for significant outcomes and 6 for nonsignificant outcomes, indicating that outcomes favoring one surgical method are more statistically fragile than those demonstrating equivalency. [Orthopedics. 2025;48(2):69-73.].

对于移位性股骨颈骨折的治疗是采用半髋关节置换术还是全髋关节置换术存在争议。本研究旨在比较这些方法的随机对照试验(rct)的脆弱性指数(FI)。我们查询了这些包含二分类结果的随机对照试验,发现11个随机对照试验有63个二分类结果。所有结果的中位FI为6,表明6次事件逆转将改变结果的统计显著性。显著结果的中位FI为2,不显著结果的中位FI为6,表明偏向一种手术方法的结果在统计学上比证明等效的结果更脆弱。[矫形手术。202 x; 4 x (x): xx-xx。]。
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引用次数: 0
Causal Association Between Primary Biliary Cholangitis and Osteoporosis: A Mendelian Randomization Study. 原发性胆道胆管炎与骨质疏松的因果关系:一项孟德尔随机研究。
IF 1.1 4区 医学 Q3 ORTHOPEDICS Pub Date : 2025-03-01 Epub Date: 2025-01-17 DOI: 10.3928/01477447-20250114-03
Wang Yan, Gou Dongkai, Shan Wenhan, Liu Quanjing, Liu Huangxing, Yuan Ye, Zhu Zhaomin

Background: As the prevalence of osteoporotic fractures increases, impacting the health of the aging population significantly, understanding the genetic link between chronic diseases such as primary biliary cholangitis (PBC) and osteoporosis (OP) is crucial. Despite existing research, the direct genetic relationship between these conditions remains unclear.

Materials and methods: This study used a two-sample Mendelian randomization approach, drawing on the largest available genome-wide association studies. Instrumental variables were selected based on single nucleotide polymorphisms to explore the genetic correlations affecting the association between PBC and OP. This method helps overcome the limitations of traditional observational studies by reducing confounding factors and preventing reverse causation.

Results: The results, primarily derived from the inverse variance weighted method along with MR-Egger and weighted median supplementary methods, demonstrated a significant causal link between the genetic markers associated with PBC and an increased risk of OP. Sensitivity analyses reinforced these findings, affirming the robustness of the genetic associations.

Conclusion: These findings highlight the genetic underpinnings that potentially link PBC to an increased risk of OP, suggesting that genetic factors play a significant role in the progression of chronic diseases. This knowledge could lead to better prevention and treatment strategies for OP, emphasizing the need for integrated treatment approaches that account for genetic predispositions of patients with chronic conditions. Future research should focus on validating these genetic links further and exploring them as potential therapeutic targets. [Orthopedics. 2025;48(2):111-115.].

背景:随着骨质疏松性骨折患病率的增加,对老龄人群的健康影响显著,了解原发性胆道胆管炎(PBC)等慢性疾病与骨质疏松症(OP)之间的遗传联系至关重要。尽管已有研究,但这些疾病之间的直接遗传关系仍不清楚。材料和方法:本研究采用双样本孟德尔随机化方法,利用最大的全基因组关联研究。基于单核苷酸多态性选择工具变量,探索影响PBC与op之间关联的遗传相关性。该方法通过减少混杂因素和防止反向因果关系,有助于克服传统观察性研究的局限性。结果:研究结果主要来源于反方差加权法以及MR-Egger和加权中位数补充法,结果表明与PBC相关的遗传标记与op风险增加之间存在显著的因果关系。敏感性分析强化了这些发现,确认了遗传关联的稳健性。结论:这些发现强调了PBC与OP风险增加之间潜在的遗传基础,表明遗传因素在慢性疾病的进展中起着重要作用。这一知识可能会导致更好的OP预防和治疗策略,强调需要综合治疗方法,考虑慢性疾病患者的遗传易感性。未来的研究应该集中在进一步验证这些遗传联系,并探索它们作为潜在的治疗靶点。[矫形手术。202; 4 x (x): xx-xx。]。
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引用次数: 0
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Orthopedics
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