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The Effectiveness of Aligners in the Treatment of Anterior Open Bite in Adult Patients: A Systematic Review and Critical Appraisal 矫治器治疗成人前牙开放性咬合的有效性:系统回顾与批判性评估
Pub Date : 2024-04-22 DOI: 10.3390/oral4020014
Tainá Iunes, Afonso Pinhão-Ferreira, V. Urzal
An anterior open bite is a dental malocclusion, the diagnosis of which is fundamental for its treatment. With the evolution of artificial intelligence, it is possible to treat it through the Invisalign G4 protocol, depending on the degree of severity. The aim of this study was to perform a systematic review, based on the PICO strategy, to evaluate the effectiveness of aligners and accessory devices in adult patients with anterior open bites. The search was carried out in the following databases for publications over the last ten years: PubMed, Web of Science, Cochrane Library, and LILACS. The inclusion criteria were clinical studies evaluating adults with anterior open bites (overbites < 0 mm) and orthodontic studies with aligners. The exclusion criteria were studies of cases with dentofacial deformities, previous orthodontic treatment, history of surgery/trauma, or systemic diseases that affect craniofacial growth, as well as animal studies, reviews, and clinical cases. The selection was carried out separately by two researchers. In the four databases, 108 articles were obtained. By reviewing the titles and abstracts and applying the exclusion criteria, 91 articles were eliminated. The seven resulting articles were submitted to the inclusion criteria, two of which were excluded due to their lack of patients presenting an open bite and the absence of aligner treatment. According to the PRISMA method, five studies were selected. The collected data showed an increase in overbites with the use of aligners. The bias assessment was performed with the ROBINS-I tool, indicating a moderate risk of bias. The included studies demonstrated the effectiveness of aligners in the treatment of adults with mild or moderate open bites; however, due to the lack of scientific evidence, it is necessary to carry out randomized studies with the same standardized variables.
前牙开合咬合是一种牙齿畸形,其诊断是治疗的基础。随着人工智能的发展,可以根据其严重程度,通过隐适美 G4 方案进行治疗。本研究的目的是根据PICO策略进行系统性回顾,评估矫治器和附属装置对前牙开合咬合成年患者的有效性。我们在以下数据库中搜索了过去十年间的出版物:PubMed、Web of Science、Cochrane Library 和 LILACS。纳入标准是评估成人前方开放性咬合(咬合过度小于 0 毫米)的临床研究和使用矫治器的正畸研究。排除标准为颌面部畸形、既往接受过正畸治疗、手术/外伤史或影响颅面生长的全身性疾病的病例研究,以及动物研究、综述和临床病例。筛选工作由两名研究人员分别进行。在四个数据库中,共获得 108 篇文章。通过审查标题和摘要并应用排除标准,共剔除了 91 篇文章。最终有7篇文章符合纳入标准,其中两篇因缺乏开放性咬合患者和未使用矫治器治疗而被排除。根据PRISMA方法,选出了五项研究。收集到的数据显示,使用矫治器后,咬合过度的情况有所增加。使用 ROBINS-I 工具进行了偏倚评估,结果显示偏倚风险适中。所纳入的研究表明,矫治器在治疗成人轻度或中度开放性咬合方面具有疗效;然而,由于缺乏科学证据,有必要进行具有相同标准化变量的随机研究。
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引用次数: 0
Experimental Evaluation of a Novel Device to Quantify Canal Cleanliness: An In Vitro Study 对一种新型设备进行实验评估,以量化管腔清洁度:体外研究
Pub Date : 2024-04-07 DOI: 10.3390/oral4020013
Lorenzo Arcuri, G. Gambarini, Alessio Zanza, L. Testarelli, Claudio Arcuri, Randolph Cross, Massimo Galli
Endodontic treatments are performed to avoid extractions and maintain the natural dentition. Root canal treatments are undertaken to eliminate or prevent an infection within the root canal system. Chemical and mechanical root canal debridement are the main methods used in endodontics to remove necrotic tissue, microorganisms, and microbial byproducts from the canal. However, to date there is no objective method to clinically determine the proper root canal disinfection level and thus proceed with the obturation. Clinicians just rely on their experience and habits or can trust in empirical methods such as the insertion of paper cones inside the canal and then check their appearance after the removal. Even in the in vitro and ex vivo scientific studies there is no objective method to analyze and compare the efficacy of different endodontic chemo-mechanical techniques and materials. The most frequently used method is to visually analyze some areas with a scanning electron microscope (SEM), even if the resulting images are hardly quantifiable and could greatly vary according to the analyzed area. A new device to clinically test the cleanliness of a root canal and display the result in an objective score was recently developed. The device analyzes the luminescence generated by an enzyme cycling method that process the adenosine triphosphate (ATP), adenosine diphosphate (ADP) and adenosine monophosphate (AMP) present in organic residues. The aim of the present in vitro study was to test the efficacy and reliability of this novel device (Endocator) in a controlled in vitro environment, before using it in clinical practice. The device sensitivity was tested on 5 single canal resin blocks. Three consecutive sampling were executed by one operator for each block to test the device repeatability. Results were recorded according to Endoscore (ES) and relative light unit (RLU) scales. Descriptive analysis and comparison between the 5 resin blocks and the 3 consecutive sampling were performed. Only the comparison between the first and third measurements both for ES (p = 0.00115999) and RLU (p = 0.00532749) resulted significant. Endocator was able to determine small variations of canal contamination in a controlled laboratory environment, showing high sensitivity and repeatability.
进行牙髓治疗是为了避免拔牙和保持天然牙列。根管治疗是为了消除或预防根管系统内的感染。化学和机械根管清创是根管治疗中用于清除根管中坏死组织、微生物和微生物副产品的主要方法。然而,迄今为止,临床上还没有一种客观的方法来确定适当的根管消毒程度,从而进行封髓。临床医生只能依靠自己的经验和习惯,或者相信经验性的方法,比如将纸锥插入根管,然后在取出后检查纸锥的外观。即使在体外和体内科学研究中,也没有客观的方法来分析和比较不同的牙髓化学机械技术和材料的功效。最常用的方法是用扫描电子显微镜(SEM)对某些区域进行直观分析,尽管所得到的图像很难量化,而且会因分析区域的不同而有很大差异。最近开发了一种新设备,用于临床检测根管的清洁度,并以客观分数显示结果。该设备通过酶循环方法分析有机残留物中的三磷酸腺苷 (ATP)、二磷酸腺苷 (ADP) 和单磷酸腺苷 (AMP) 所产生的荧光。本体外研究的目的是在将这种新型装置(Endocator)用于临床实践之前,在受控体外环境中测试其功效和可靠性。该装置的灵敏度在 5 个单管树脂块上进行了测试。每个树脂块由一名操作员连续取样三次,以测试设备的可重复性。测试结果按照内窥镜评分(ES)和相对光单位(RLU)进行记录。对 5 个树脂块和 3 次连续取样进行了描述性分析和比较。只有第一次和第三次测量的 ES 值(p = 0.00115999)和 RLU 值(p = 0.00532749)之间的比较具有显著性。Endocator 能够在受控的实验室环境中确定牙管污染的微小变化,显示出较高的灵敏度和可重复性。
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引用次数: 0
Evaluation of Enamel Volume Loss after Exposure to Energy Drinks 评估接触能量饮料后牙釉质体积的损失
Pub Date : 2024-02-23 DOI: 10.3390/oral4010009
Karen A. Schulze, Noëlle M. Santucci, Bina Surti, Stefan Habelitz, Mouchumi Bhattacharyya, Warden Noble
Objectives: This study was conducted to determine the erosive potential of various commercial energy drinks (EDs), sports drinks (SDs), and sugar sweetened beverages (SSBs) and to correlate quantitative changes in tooth enamel volume loss based on the pH and titratable acidity of the drinks. Methods: A flat plane on the facial surface of 36 human incisor teeth was created and embedded in sample holders using resin. After pre-scanning with a profilometer (Proscan 2000, Scantron, Ind Products Ltd., Taunton, UK), the six samples per group were immersed for 4 h into either Monster Energy™ (ED), Rockstar™ (ED), Red Bull™ (ED), or 5-h Energy™ (ED) and, for comparison with a sports drink, Gatorade™ (SD) and a sugar sweetened beverage, Coca-Cola® (SSB). After immersion and post-scanning, the quantitative volume loss of the tooth enamel of the 36 samples was calculated (Proscan 3D software V2.1.1.15B), and the pH and titratable acidity (TA) of each drink was determined. Results: All drinks tested caused enamel volume loss. The actual amount varied among the different drinks, from 0.39 mm3 for Red Bull™, up to 1.01 mm3 for Gatorade™. The pH measurements differed for each drink, ranging from 2.6 to 3.7. There was a small reverse correlation of 0.326 between the pH of all drinks and volume loss. Among the energy drinks, titratable acidity was similar and there was only a weak correlation between TA and volume loss (0.319 at p = 0.53). Conclusions: Energy drinks, sugar sweetened beverages, and sport drinks all have the potential to cause enamel tooth surface loss resulting in demineralization. Therefore, the pH of a drink cannot be the sole determinant for choosing a less harmful commercial beverage.
研究目的本研究旨在确定各种商业能量饮料(ED)、运动饮料(SD)和含糖饮料(SSB)的侵蚀潜力,并根据饮料的 pH 值和可滴定酸度对牙釉质体积损失的定量变化进行相关分析。研究方法在 36 颗人类门牙的面部创建一个平面,并用树脂将其嵌入样本夹中。使用轮廓仪(Proscan 2000,Scantron,Ind Products Ltd.,Taunton,UK)进行预扫描后,将每组的 6 个样本分别浸入 Monster Energy™ (ED)、Rockstar™ (ED)、Red Bull™ (ED) 或 5-h Energy™ (ED) 中 4 小时,并与运动饮料佳得乐™ (SD) 和含糖饮料可口可乐® (SSB) 进行比较。浸泡和扫描后,计算 36 个样本的牙釉质定量体积损失(Proscan 3D 软件 V2.1.1.15B),并测定每种饮料的 pH 值和可滴定酸度(TA)。结果所有测试饮料都会造成牙釉质体积损失。不同饮料的实际损失量各不相同,红牛™的损失量为0.39立方毫米,佳得乐™的损失量则高达1.01立方毫米。每种饮料的 pH 值测量值也不同,从 2.6 到 3.7 不等。所有饮料的 pH 值与体积损失之间存在 0.326 的微小反向相关性。在能量饮料中,可滴定酸度相似,可滴定酸度与体积损失之间只有微弱的相关性(0.319,p = 0.53)。结论能量饮料、含糖饮料和运动饮料都有可能导致釉质牙齿表面脱落,造成牙齿脱矿。因此,饮料的酸碱度不能作为选择危害较小的商业饮料的唯一决定因素。
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引用次数: 0
Teaching of Forensic Dentistry in Khartoum, Sudan 苏丹喀土穆的法医牙科教学
Pub Date : 2024-02-04 DOI: 10.3390/oral4010008
Sarah Hag Ali, A. Franco, Emilio Nuzzolese, S. Mânica
Background: Dental professionals assist with legal and criminal matters through the practice of forensic dentistry which has evolved over the past century and is now a crucial component of undergraduate dental education in many nations. The need for formal training in the subject and its inclusion in dental curricula were acknowledged and addressed in the 1960s and 1970s. Aims: This study aimed to investigate the teaching of forensic dentistry in dental universities of Khartoum, Sudan, and to propose certain topics and teaching criteria to be standardized in forensic dentistry teaching in Sudan. Materials and methods: An observational, descriptive study was conducted, involving all undergraduate dental institutions in Khartoum, Sudan. Institutional websites were searched using the Google search engine to obtain the dental program curricula in English. The curricula were then analyzed to identify the presence of forensic odontology/dentistry teaching. Results: Of the 19 universities included in the study, five (26.3%) teach forensic dentistry in their undergraduate curricula, whereas 12 (63.1%) do not. Two universities (10.6%) indicated the presence of forensic dentistry teaching in their curricula but did not provide actual instruction. The teaching of forensic dentistry mainly occurred during the second, third, and fourth years of the dental program. Three universities considered it an independent subject, while two universities incorporated it into oral and maxillofacial pathology. Four universities provided lectures only, while one university combined lectures and practical sessions. Qualified forensic dentists taught the subject in four universities, while one university had general dentists as instructors. The main topics delivered are: (1) introduction to forensics, (2) human identification, (3) dental age estimation, (4) interpretation of bitemarks, (5) DNA in forensics, and (6) child abuse. Conclusion: Forensic dentistry training is currently undervalued in Sudan due to various limitations. It is recommended that all dental schools in Sudan offer opportunities for students to learn and become acquainted with forensic dentistry as part of their dental programs. The Sudanese Dental Council should establish formal coordination with academic institutions and experienced forensic dentists to ensure the quality and relevance of the proposed modular course within the educational system. Finally, additional topics including dental record-keeping and dental malpractice are suggested for inclusion in the current modules.
背景:牙科专业人员通过法医口腔医学的实践协助处理法律和刑事案件。法医口腔医学在过去的一个世纪中不断发展,现在已经成为许多国家本科牙科教育的重要组成部分。20 世纪 60 年代和 70 年代,人们认识到需要对该学科进行正规培训,并将其纳入牙科课程。目的:本研究旨在调查苏丹喀土穆牙科大学的法医牙科学教学情况,并就苏丹法医牙科学教学中应标准化的某些主题和教学标准提出建议。材料和方法:进行了一项观察性、描述性研究,涉及苏丹喀土穆的所有本科牙科院校。研究人员使用谷歌搜索引擎搜索了各院校的网站,以获取英文版的牙科专业课程。然后对课程进行分析,以确定是否存在法医牙体/牙科学教学。结果:在参与研究的 19 所大学中,有 5 所大学(26.3%)在本科课程中教授法医牙科学,而有 12 所大学(63.1%)没有教授法医牙科学。两所大学(10.6%)表示在其课程中开设了法医牙科学教学,但并未提供实际教学。法医牙科学的教学主要发生在牙科专业的第二、第三和第四年。三所大学将其视为一门独立的学科,而两所大学则将其纳入口腔颌面病理学中。四所大学只提供讲座,一所大学则将讲座和实践课程结合起来。四所大学由合格的法医牙科医生授课,一所大学由普通牙科医生授课。讲授的主要内容有(1) 法医入门,(2) 人体识别,(3) 牙齿年龄估计,(4) 咬痕解释,(5) 法医中的 DNA,以及 (6) 虐待儿童。结论:由于各种限制,苏丹目前对法医牙科培训的重视程度不足。建议苏丹的所有牙科学校为学生提供学习和熟悉法医牙科的机会,作为其牙科课程的一部分。苏丹牙科理事会应与学术机构和经验丰富的法医牙医建立正式的协调关系,以确保教育系统中拟议的模块课程的质量和相关性。最后,建议将包括牙科记录保存和牙科渎职在内的其他主题纳入当前的模块中。
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引用次数: 0
Teaching of Forensic Dentistry in Khartoum, Sudan 苏丹喀土穆的法医牙科教学
Pub Date : 2024-02-04 DOI: 10.3390/oral4010008
Sarah Hag Ali, A. Franco, Emilio Nuzzolese, S. Mânica
Background: Dental professionals assist with legal and criminal matters through the practice of forensic dentistry which has evolved over the past century and is now a crucial component of undergraduate dental education in many nations. The need for formal training in the subject and its inclusion in dental curricula were acknowledged and addressed in the 1960s and 1970s. Aims: This study aimed to investigate the teaching of forensic dentistry in dental universities of Khartoum, Sudan, and to propose certain topics and teaching criteria to be standardized in forensic dentistry teaching in Sudan. Materials and methods: An observational, descriptive study was conducted, involving all undergraduate dental institutions in Khartoum, Sudan. Institutional websites were searched using the Google search engine to obtain the dental program curricula in English. The curricula were then analyzed to identify the presence of forensic odontology/dentistry teaching. Results: Of the 19 universities included in the study, five (26.3%) teach forensic dentistry in their undergraduate curricula, whereas 12 (63.1%) do not. Two universities (10.6%) indicated the presence of forensic dentistry teaching in their curricula but did not provide actual instruction. The teaching of forensic dentistry mainly occurred during the second, third, and fourth years of the dental program. Three universities considered it an independent subject, while two universities incorporated it into oral and maxillofacial pathology. Four universities provided lectures only, while one university combined lectures and practical sessions. Qualified forensic dentists taught the subject in four universities, while one university had general dentists as instructors. The main topics delivered are: (1) introduction to forensics, (2) human identification, (3) dental age estimation, (4) interpretation of bitemarks, (5) DNA in forensics, and (6) child abuse. Conclusion: Forensic dentistry training is currently undervalued in Sudan due to various limitations. It is recommended that all dental schools in Sudan offer opportunities for students to learn and become acquainted with forensic dentistry as part of their dental programs. The Sudanese Dental Council should establish formal coordination with academic institutions and experienced forensic dentists to ensure the quality and relevance of the proposed modular course within the educational system. Finally, additional topics including dental record-keeping and dental malpractice are suggested for inclusion in the current modules.
背景:牙科专业人员通过法医口腔医学的实践协助处理法律和刑事案件。法医口腔医学在过去的一个世纪中不断发展,现在已经成为许多国家本科牙科教育的重要组成部分。20 世纪 60 年代和 70 年代,人们认识到需要对该学科进行正规培训,并将其纳入牙科课程。目的:本研究旨在调查苏丹喀土穆牙科大学的法医牙科学教学情况,并就苏丹法医牙科学教学中应标准化的某些主题和教学标准提出建议。材料和方法:进行了一项观察性、描述性研究,涉及苏丹喀土穆的所有本科牙科院校。研究人员使用谷歌搜索引擎搜索了各院校的网站,以获取英文版的牙科专业课程。然后对这些课程进行分析,以确定是否存在法医牙体/牙科学教学。结果:在参与研究的 19 所大学中,有 5 所大学(26.3%)在本科课程中教授法医牙科学,而有 12 所大学(63.1%)没有教授法医牙科学。两所大学(10.6%)表示在其课程中开设了法医牙科学教学,但并未提供实际教学。法医牙科学的教学主要发生在牙科专业的第二、第三和第四年。三所大学将其视为一门独立的学科,而两所大学则将其纳入口腔颌面病理学中。四所大学只提供讲座,一所大学则将讲座和实践课程结合起来。四所大学由合格的法医牙科医生授课,一所大学由普通牙科医生授课。讲授的主要内容有(1) 法医入门,(2) 人体识别,(3) 牙齿年龄估计,(4) 咬痕解释,(5) 法医中的 DNA,以及 (6) 虐待儿童。结论:由于各种限制,苏丹目前对法医牙科培训的重视程度不足。建议苏丹的所有牙科学校为学生提供学习和熟悉法医牙科的机会,作为其牙科课程的一部分。苏丹牙科理事会应与学术机构和经验丰富的法医牙医建立正式的协调关系,以确保教育系统中拟议的模块课程的质量和相关性。最后,建议将包括牙科记录保存和牙科渎职在内的其他主题纳入当前的模块中。
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引用次数: 0
Treatment Strategies for Incisors of Children Affected by Molar Incisor Hypomineralization: A Narrative Review 针对受磨牙门牙矿化不足影响的儿童的门牙治疗策略:叙述性综述
Pub Date : 2024-02-01 DOI: 10.3390/oral4010007
B. Sezer, Burak Çarıkçıoğlu
Today, molar incisor hypomineralization (MIH), which affects approximately one in seven children, is defined as a hypomineralized developmental enamel defect that often impacts at least one permanent first molar and frequently affects permanent incisors as well. Symptoms and signs include demarcated opacities of various colors, post-eruptive enamel deterioration, atypical caries and restorations, hypersensitivity, tooth loss due to MIH, and difficulty in achieving anesthesia. A detailed review of the scientific literature shows that there are many studies evaluating different treatment approaches for permanent first molars affected by MIH. On the other hand, there are very few scientific studies evaluating treatment approaches for affected incisors in patients with MIH. Most of these studies consist of case reports or series. White/creamy and/or yellow/brown demarcated opacities are commonly observed in affected incisors in patients with MIH. While these opacities increase the susceptibility of enamel to deterioration and dental caries, they also cause aesthetic problems and related psychosocial consequences. Treatment methods, such as resin infiltration, microabrasion, and/or dental bleaching, have been proposed for aesthetic and restorative purposes in affected incisors in patients with MIH. Additionally, various approaches to increase mineral content and relieve hypersensitivity have been recommended. The number of randomized controlled and prospective studies is quite low, but many case reports and case series have been encountered. The purpose of this review was to provide a comprehensive overview of the different treatment management modalities for permanent incisors affected by MIH. As a result, while resin infiltration, dental bleaching, microabrasion, and/or etch–bleach–seal techniques are preferred for aesthetic and restorative purposes in these teeth, it has been observed that agents containing casein phosphopeptide amorphous calcium phosphate, casein phosphopeptide amorphous calcium fluoride phosphate, fluoride, and calcium glycerophosphate increase the mineral content. Additionally, studies have reported that ozone and low-level laser therapy, in addition to these remineralizing agents, reduce hypersensitivity in these teeth. Although the findings of this review indicate that the level of evidence for current approaches is not high, clinicians may prefer one or more of the treatment approaches mentioned in this article based on experience and patient expectations.
如今,每七名儿童中就有一名患有臼齿切牙低矿化症(MIH),它被定义为一种低矿化的发育性珐琅质缺陷,通常至少会影响到一颗永久性第一臼齿,也经常会影响到永久性切牙。症状和体征包括各种颜色的分界不透明、萌发后釉质退化、非典型龋齿和修复体、过敏、MIH 导致的牙齿脱落以及麻醉困难。对科学文献的详细回顾表明,有许多研究评估了针对受MIH影响的第一恒磨牙的不同治疗方法。另一方面,很少有科学研究对 MIH 患者受影响切牙的治疗方法进行评估。这些研究大多是病例报告或系列研究。在 MIH 患者受影响的门牙上,通常会观察到白色/乳白色和/或黄色/棕色的分界不透明。这些牙釉质不透明会增加牙釉质退化和龋齿的可能性,同时也会造成美观问题和相关的社会心理后果。为了美观和修复 MIH 患者受影响的门牙,人们提出了树脂渗透、微磨蚀和/或牙齿漂白等治疗方法。此外,还推荐了各种增加矿物质含量和缓解过敏性的方法。随机对照研究和前瞻性研究的数量很少,但也有许多病例报告和系列病例。本综述的目的是全面概述针对受MIH影响的恒切牙的不同治疗管理模式。因此,虽然树脂浸润、牙齿漂白、微磨蚀和/或蚀刻-漂白-密封技术是这些牙齿美观和修复的首选方法,但也观察到含有酪蛋白磷酸肽无定形磷酸钙、酪蛋白磷酸肽无定形氟化磷酸钙、氟化物和甘油磷酸钙的制剂可增加矿物质含量。此外,有研究报告称,除了这些再矿化剂之外,臭氧和低强度激光疗法还能降低这些牙齿的过敏性。尽管本综述的研究结果表明目前的方法证据水平不高,但临床医生可能会根据经验和患者的期望偏好本文中提到的一种或多种治疗方法。
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引用次数: 0
Treatment Strategies for Incisors of Children Affected by Molar Incisor Hypomineralization: A Narrative Review 针对受磨牙门牙矿化不足影响的儿童的门牙治疗策略:叙述性综述
Pub Date : 2024-02-01 DOI: 10.3390/oral4010007
B. Sezer, Burak Çarıkçıoğlu
Today, molar incisor hypomineralization (MIH), which affects approximately one in seven children, is defined as a hypomineralized developmental enamel defect that often impacts at least one permanent first molar and frequently affects permanent incisors as well. Symptoms and signs include demarcated opacities of various colors, post-eruptive enamel deterioration, atypical caries and restorations, hypersensitivity, tooth loss due to MIH, and difficulty in achieving anesthesia. A detailed review of the scientific literature shows that there are many studies evaluating different treatment approaches for permanent first molars affected by MIH. On the other hand, there are very few scientific studies evaluating treatment approaches for affected incisors in patients with MIH. Most of these studies consist of case reports or series. White/creamy and/or yellow/brown demarcated opacities are commonly observed in affected incisors in patients with MIH. While these opacities increase the susceptibility of enamel to deterioration and dental caries, they also cause aesthetic problems and related psychosocial consequences. Treatment methods, such as resin infiltration, microabrasion, and/or dental bleaching, have been proposed for aesthetic and restorative purposes in affected incisors in patients with MIH. Additionally, various approaches to increase mineral content and relieve hypersensitivity have been recommended. The number of randomized controlled and prospective studies is quite low, but many case reports and case series have been encountered. The purpose of this review was to provide a comprehensive overview of the different treatment management modalities for permanent incisors affected by MIH. As a result, while resin infiltration, dental bleaching, microabrasion, and/or etch–bleach–seal techniques are preferred for aesthetic and restorative purposes in these teeth, it has been observed that agents containing casein phosphopeptide amorphous calcium phosphate, casein phosphopeptide amorphous calcium fluoride phosphate, fluoride, and calcium glycerophosphate increase the mineral content. Additionally, studies have reported that ozone and low-level laser therapy, in addition to these remineralizing agents, reduce hypersensitivity in these teeth. Although the findings of this review indicate that the level of evidence for current approaches is not high, clinicians may prefer one or more of the treatment approaches mentioned in this article based on experience and patient expectations.
如今,每七名儿童中就有一名患有臼齿切牙低矿化症(MIH),它被定义为一种低矿化的发育性珐琅质缺陷,通常至少会影响到一颗永久性第一臼齿,也经常会影响到永久性切牙。症状和体征包括各种颜色的分界不透明、萌发后釉质退化、非典型龋齿和修复体、过敏、MIH 导致的牙齿脱落以及麻醉困难。对科学文献的详细回顾表明,有许多研究评估了针对受MIH影响的第一恒磨牙的不同治疗方法。另一方面,很少有科学研究对 MIH 患者受影响切牙的治疗方法进行评估。这些研究大多是病例报告或系列研究。在 MIH 患者受影响的门牙上,通常会观察到白色/乳白色和/或黄色/棕色的分界不透明。这些牙釉质不透明会增加牙釉质退化和龋齿的可能性,同时也会造成美观问题和相关的社会心理后果。为了美观和修复 MIH 患者受影响的门牙,人们提出了树脂渗透、微磨蚀和/或牙齿漂白等治疗方法。此外,还推荐了各种增加矿物质含量和缓解过敏性的方法。随机对照研究和前瞻性研究的数量很少,但也有许多病例报告和系列病例。本综述的目的是全面概述针对受MIH影响的恒切牙的不同治疗管理模式。因此,虽然树脂浸润、牙齿漂白、微磨蚀和/或蚀刻-漂白-密封技术是这些牙齿美观和修复的首选方法,但也观察到含有酪蛋白磷酸肽无定形磷酸钙、酪蛋白磷酸肽无定形氟化磷酸钙、氟化物和甘油磷酸钙的制剂可增加矿物质含量。此外,有研究报告称,除了这些再矿化剂之外,臭氧和低强度激光疗法还能降低这些牙齿的过敏性。尽管本综述的研究结果表明目前的方法证据水平不高,但临床医生可能会根据经验和患者的期望偏好本文中提到的一种或多种治疗方法。
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引用次数: 0
Periodontitis and Alzheimer’s Disease: Is There a Connection? 牙周炎与阿尔茨海默病:两者之间有联系吗?
Pub Date : 2024-01-22 DOI: 10.3390/oral4010006
William Lundergan, Kavitha Parthasarathy, Navid Knight
The oral health/systemic health connection has been an area of research interest that increased dramatically during the 1990s. Periodontal disease has been associated with a number of systemic conditions, including cardiovascular disease, diabetes, pre-term low-birth-weight infants, respiratory conditions, rheumatoid arthritis, cancer, and Alzheimer’s disease. Inflammation is the obvious link that connects periodontal disease with these conditions, but is this association casual or causal? We will address the biologic plausibility, evidence from human studies, evidence from animal studies, and therapeutic interventions as we review the current understanding of the link between periodontitis and Alzheimer’s disease.
口腔健康与全身健康之间的联系是一个研究兴趣在 20 世纪 90 年代急剧增长的领域。牙周病与许多全身性疾病有关,包括心血管疾病、糖尿病、早产低体重儿、呼吸系统疾病、类风湿性关节炎、癌症和阿尔茨海默病。炎症是牙周病与这些疾病之间的明显联系,但这种联系是偶然的还是因果的?在回顾目前对牙周炎与阿尔茨海默病之间联系的理解时,我们将讨论生物合理性、人体研究证据、动物研究证据和治疗干预措施。
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引用次数: 0
Intentional Dental Modifications in the African Population 非洲人的有意牙齿改造
Pub Date : 2024-01-18 DOI: 10.3390/oral4010005
Candy Kgabi, S. Mânica, Hemlata Pandey
(1) This research paper aims to conduct a comprehensive review of the existing scientific literature on intentional dental modifications within the African population. By synthesizing and analysing studies, this paper aims to shed light on the prevalence, cultural significance, and forensic implications of intentional dental modifications. (2) A scoping review was conducted according to PRISMA for Scoping Reviews and a search performed in June 2023 on the three electronic databases Scopus, PubMed, and Web of Science. (3) The search resulted in 30 studies and showed that intentional dental modifications, also referred to as nontherapeutic dental modifications, are prevalent across the African population for reasons linked to traditional medicine, ethnic affiliation, and individualism, with the highest-reported modification being infant oral mutilation at 53%, followed by tooth filing at 10%, and others such as lip plates, diastema piercings, dental avulsion, dental tattooing, crowns, and oral piercings. (4) The quality and quantity of the available literature on intentional dental modifications in the African population is limited due to bias in reporting, as most studies are those of individuals with severe health complications. The data gathered from this study could further aid in the analysis and identification of nontherapeutic dental modifications, be used in profiling, and assist in the estimation of population affiliation.
(1) 本研究论文旨在对现有的关于非洲人故意改造牙齿的科学文献进行全面回顾。通过对研究进行综合和分析,本文旨在阐明故意改装牙齿的普遍性、文化意义和法医学影响。(2)2023年6月,根据《范围界定综述的PRISMA》进行了范围界定综述,并在Scopus、PubMed和Web of Science三个电子数据库中进行了检索。(3)检索结果显示,出于传统医学、种族归属和个人主义等原因,有意的牙齿修饰(也称为非治疗性牙齿修饰)在非洲人口中十分普遍,其中报告率最高的牙齿修饰是婴儿口腔残割,占 53%,其次是锉牙,占 10%,其他还有唇板、齿间穿孔、牙齿撕脱、牙齿纹身、牙冠和口腔穿孔等。(4)由于大多数研究都是针对有严重健康并发症的人,因此关于非洲人故意修饰牙齿的现有文献在质量和数量上都很有限,这是因为报告存在偏差。本研究收集的数据可进一步帮助分析和识别非治疗性的牙齿修饰,用于特征分析,并有助于估计人口的隶属关系。
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引用次数: 0
Effectiveness of Bioactive Toothpastes against Dentin Hypersensitivity Using Evaporative and Tactile Analyses: A Randomized Clinical Trial 使用蒸发和触觉分析生物活性牙膏对牙本质过敏症的疗效:随机临床试验
Pub Date : 2024-01-10 DOI: 10.3390/oral4010004
Roberta Caroline Bruschi Alonso, Letícia de Oliveira, Jaqueline Alves Batista Silva, Williane Bernadete Bezerra dos Santos, Lúria Ribeiro de Souza Laranja Ferreira, R. Guiraldo, F. Vilhena, P. D’Alpino
The objective of this study was to investigate and compare the effectiveness of toothpastes containing bioactives to relieve dentin hypersensitivity with that of a commercial desensitizing toothpaste containing REFIX technology, associated or not with a calcium booster. In this double-blind, randomized, parallel-group, multi-center clinical trial, thirty-two volunteers diagnosed with dentin hypersensitivity and qualified to participate were randomized into four groups: (1) Colgate Sensitive Pro-Relief; (2) Sensodyne Repair & Relief; (3) Regenerador Sensitive; and (4) Regenerador Sensitive, associated with a calcium booster. Evaporative and tactile tests were used to check for dentin hypersensitivity in the test subjects. The participants brushed their teeth with one of the toothpastes, and dentin hypersensitivity was immediately tested using a visual analogue scale (VAS), in which the pain was rated on a scale of 0 to 10. Dentin hypersensitivity was measured after one week and after one month of the subjects continuing to use the toothpaste three times per day. Data were statistically analyzed with a non-parametric Friedman test for dependent data (α = 0.05). All toothpastes reduced dentin hypersensitivity. In the evaporative test, Sensodyne Protect & Repair and Regenerador Sensitive, associated with the calcium booster, exhibited faster and more effective results in reducing pain caused by dentin hypersensitivity, even after the first use. Colgate Sensitive Pro-Relief was effective only after one week of use. All toothpastes performed well in the tactile test for treating dentin hypersensitivity, and their performance improved over time. Sensodyne Repair & Protect presented the highest overall pain remission after one month (84.6%). The bioactive toothpastes reduced, to a different extent, the tooth hypersensitivity reported by the volunteers. Sensodyne Repair & Relief and Regenerador Sensitive, associated or not with a calcium booster, presented faster and more effective results in reducing pain caused by dentin hypersensitivity.
这项研究的目的是调查和比较含有生物活性成分的牙膏与含有 REFIX 技术的商用脱敏牙膏在缓解牙本质过敏症方面的效果,以及是否与钙增效剂结合使用。在这项双盲、随机、平行组、多中心临床试验中,32 名被诊断为牙本质过敏症并符合参与条件的志愿者被随机分为四组:(1) 高露洁敏感型专业舒缓牙膏;(2) 感舒宝修复舒缓牙膏;(3) Regenerador 敏感型牙膏;(4) Regenerador 敏感型牙膏(含钙增效剂)。采用蒸发测试和触觉测试来检查受试者的牙本质过敏症。受试者用其中一种牙膏刷牙后,立即使用视觉模拟量表(VAS)对牙本质过敏性进行测试,疼痛程度从 0 到 10 分不等。受试者继续每天使用牙膏三次,分别在一周后和一个月后测量牙本质过敏性。数据采用非参数弗里德曼检验进行统计分析(α = 0.05)。所有牙膏都降低了牙本质过敏性。在蒸发试验中,含有钙增效剂的舒敏防护修复牙膏和敏感再生牙膏在减轻牙本质过敏引起的疼痛方面表现得更快、更有效,即使在第一次使用后也是如此。高露洁敏感型专业舒缓牙膏仅在使用一周后才见效。在治疗牙本质过敏症的触觉测试中,所有牙膏都表现良好,而且随着时间的推移,它们的表现都有所改善。一个月后,敏感修复和保护牙膏的总体疼痛缓解率最高(84.6%)。生物活性牙膏在不同程度上减轻了志愿者的牙齿过敏症状。无论是否添加了钙增效剂,舒肤佳修复舒缓型和再生敏感型牙膏都能更快更有效地减轻牙本质过敏引起的疼痛。
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引用次数: 0
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