K. Zhamaldinov, M. Ismailova, D. Makataeva, I. Smolinov, K. Sharipbai, Z. Sharipova, A. Shokebaev, N.T. Orynbasar
Hyperthyroidism (Graves’ disease (GD)), is a relatively rare disease in adults and children. Treatment options for adults and children are antithyroid drugs (ATD), radioactive iodine (RAI), or thyroidectomy, but the risks as well as benefits of each are different.
{"title":"GRAVES DISEASE","authors":"K. Zhamaldinov, M. Ismailova, D. Makataeva, I. Smolinov, K. Sharipbai, Z. Sharipova, A. Shokebaev, N.T. Orynbasar","doi":"10.35805/bsk2022iv047","DOIUrl":"https://doi.org/10.35805/bsk2022iv047","url":null,"abstract":"Hyperthyroidism (Graves’ disease (GD)), is a relatively rare disease in adults and children. Treatment options for adults and children are antithyroid drugs (ATD), radioactive iodine (RAI), or thyroidectomy, but the risks as well as benefits of each are different.","PeriodicalId":197118,"journal":{"name":"BULLETIN OF SURGERY IN KAZAKHSTAN","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128995456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N.K. Tazhimuratov, S.A. Makhanov, D.K. Zhamashev, B.A. Montaev, A.K. Khamidolla, A. Zhorabek
The article summarizes a case from practice, which describes the comprehensive treatment of a patient with a deep contact burn of the face. Throughout the development of humankind, people have been faced with the need to treat severe wounds, with facial injuries being of particular importance. Ancient sources describe that facial injuries were very common in Ancient India and the countries of the Middle East. Patient S. was admitted to the Alma-ata City Emergency Hospital in 2019. She received a thermal injury at home, according to the patient, she lost consciousness while cooking and fell on a burning gas stove burner. Upon admission, the general condition of the patient was severe, due to the injury and the presence of somatic pathology. The postoperative period was uneventful. Thus, in order to obtain satisfactory results in the surgical treatment of deep burns of the face, one operation is not enough, complex treatment is required, which includes physiotherapy and corrective operations, this is the only way to achieve the optimal, i.e. desired result. The need to develop new recommendations and their practical implementation for the treatment of this pathology will improve the quality and optimize the treatment of victims.
{"title":"COMPREHENSIVE TREATMENT OF DEEP FACIAL BURNS. A CLINICAL CASE","authors":"N.K. Tazhimuratov, S.A. Makhanov, D.K. Zhamashev, B.A. Montaev, A.K. Khamidolla, A. Zhorabek","doi":"10.35805/bsk2022iv034","DOIUrl":"https://doi.org/10.35805/bsk2022iv034","url":null,"abstract":"The article summarizes a case from practice, which describes the comprehensive treatment of a patient with a deep contact burn of the face. Throughout the development of humankind, people have been faced with the need to treat severe wounds, with facial injuries being of particular importance. Ancient sources describe that facial injuries were very common in Ancient India and the countries of the Middle East. Patient S. was admitted to the Alma-ata City Emergency Hospital in 2019. She received a thermal injury at home, according to the patient, she lost consciousness while cooking and fell on a burning gas stove burner. Upon admission, the general condition of the patient was severe, due to the injury and the presence of somatic pathology. The postoperative period was uneventful. Thus, in order to obtain satisfactory results in the surgical treatment of deep burns of the face, one operation is not enough, complex treatment is required, which includes physiotherapy and corrective operations, this is the only way to achieve the optimal, i.e. desired result. The need to develop new recommendations and their practical implementation for the treatment of this pathology will improve the quality and optimize the treatment of victims.","PeriodicalId":197118,"journal":{"name":"BULLETIN OF SURGERY IN KAZAKHSTAN","volume":"196 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120898430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective.This research ismeant to study the features of the clinical course and to developanoptimal algorithm for the diagnosis of autoimmune thyroiddiseases. Material and methods.The work is based on the examination and treatment data of 481 patients with autoimmune diseases of the thyroid gland, treated in the clinic.Diagnosis and treatment results of 481 patients were analyzed to develop an optimal algorithm for diagnosingautoimmune thyroiditis.The differential diagnostic capabilities of clinical, laboratory, and morphological examination methods of patients withautoimmune thyroiddiseases have been specified.The study of long-term results of treatment was carried out on 340patients, taking into account the various methods of treatment they underwent. Results.The analysis of existing diagnostic tools and methods allowed us to develop an optimal algorithm for diagnosingautoimmune thyroiddiseases, which is a complex of clinical, laboratory, and morphological methods that can reliably verify the diagnosis of autoimmune thyroiditis. Based on the examination results, it is possible to predict the likelihood of surgical treatment and to identify a group of patients in whom autoimmune processes can progress in the thyroid residue, contributing to the development of postoperative recurrence of the disease or causing its atrophy. Conclusion. Based on the study’s results, a rational algorithm for diagnostic search has been developed. The proposed algorithm allows, in the shortest possible time, to identify the presence of a form of autoimmune thyroiddisease and to determine the optimal tactics to treat patients withautoimmune thyroiditis based on clinical, laboratory, immunological tests and instrumental examinations.
{"title":"MODERN ASPECTS OF DIAGNOSTICS OF AUTOIMMUNE DISEASES OF THE THYROID GLAND","authors":"F.G. Sadykhov","doi":"10.35805/bsk2022iv052","DOIUrl":"https://doi.org/10.35805/bsk2022iv052","url":null,"abstract":"Objective.This research ismeant to study the features of the clinical course and to developanoptimal algorithm for the diagnosis of autoimmune thyroiddiseases. Material and methods.The work is based on the examination and treatment data of 481 patients with autoimmune diseases of the thyroid gland, treated in the clinic.Diagnosis and treatment results of 481 patients were analyzed to develop an optimal algorithm for diagnosingautoimmune thyroiditis.The differential diagnostic capabilities of clinical, laboratory, and morphological examination methods of patients withautoimmune thyroiddiseases have been specified.The study of long-term results of treatment was carried out on 340patients, taking into account the various methods of treatment they underwent. Results.The analysis of existing diagnostic tools and methods allowed us to develop an optimal algorithm for diagnosingautoimmune thyroiddiseases, which is a complex of clinical, laboratory, and morphological methods that can reliably verify the diagnosis of autoimmune thyroiditis. Based on the examination results, it is possible to predict the likelihood of surgical treatment and to identify a group of patients in whom autoimmune processes can progress in the thyroid residue, contributing to the development of postoperative recurrence of the disease or causing its atrophy. Conclusion. Based on the study’s results, a rational algorithm for diagnostic search has been developed. The proposed algorithm allows, in the shortest possible time, to identify the presence of a form of autoimmune thyroiddisease and to determine the optimal tactics to treat patients withautoimmune thyroiditis based on clinical, laboratory, immunological tests and instrumental examinations.","PeriodicalId":197118,"journal":{"name":"BULLETIN OF SURGERY IN KAZAKHSTAN","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116187174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zh.R Ospan, M. Doskhanov, E. Serikuly, D. Mukazhanov, A.A. Hadjieva, S. Tileuov, A. Skakbayev, B. Askeev, Zhasulan Baimakhanov, S. Kaniyev, A. Chormanov, B. Baimakhanov, M. Seisembayev
Acute obstructive cholecystitis is a common disease with a significant risk of mortality and complications. Active surgical tactics, such as open and laparoscopic access, pose a significant risk for elderly patients with concomitant diseases on the background of acute cholecystitis. The aim of our study is to analyze the effectiveness of percutaneous transhepatic cholecystostomy (PTCS) in acute obstructive cholecystitis (AOC) and subsequent laparoscopic cholecystectomy (LCE). Materials and methods. Retrospectively, we analyzed 64 patients treated with AOC in the period from 2017 to 2021 at the NSCS named after A.N. Syzganov. We divided them into 2 groups depending on surgical treatment. The first group: patients who were performedPTCS (n=29) at the first stage. The second stage, LCE was performed during the waiting period from 3 days to 72 days. The second group: patients who underwent LCE without drainage of the gallbladder (n=35). Also, the patients of the first group were divided into 3 subgroups depending on the waiting time: group A - LCE was performed within 10 days after PTCS, subgroup B - LCE was performed after from 2 to 4 weeks (n=12), patients of the subgroup C, LCE were performed after 4 weeks after PTCS. Preoperative, intraoperative data and postoperative complications were analyzed. Results. According to preoperative data, there was no significant difference in body temperature, laboratory data and concomitant diseases. The statistical difference was revealed only in the age of patients (65.3±9.0 vs 53.4±15.4). The duration of the operation in the second group of LCE was longer compared to the first group, but no significant difference was detected (108.1 ± 30.5 vs 117.9 ± 39.9). In the postoperative period after LCE, complications were observed in 5 (14.2%) cases: bleeding in 4 (11.4%) cases and suppuration of the postoperative wound in 1 (2.8%) case. Conversion was performed in 10 (15.6%) cases, and in one (1.5%) case, the choledochal wall was injured intraoperatively. There was no significant difference between groups A, B and C. Conclusion.The use of two-stage treatment significantly reduces the conversion to open surgery, significantly reduces postoperative complications and hospital stay in the postoperative period. According to the results of our research, the most optimal interval between PTCS and LCE is a period of more than 4 weeks.
急性梗阻性胆囊炎是一种常见的疾病，具有显著的死亡率和并发症风险。积极的手术策略，如开放和腹腔镜进入，对急性胆囊炎背景下伴有疾病的老年患者构成重大风险。我们的研究目的是分析经皮经肝胆囊造口术(PTCS)治疗急性梗阻性胆囊炎(AOC)和随后的腹腔镜胆囊切除术(LCE)的有效性。材料和方法。回顾性分析了以A.N. Syzganov命名的NSCS在2017年至2021年期间接受AOC治疗的64例患者。根据手术治疗情况分为两组。第一组:在第一阶段行ptcs的患者(n=29)。第二阶段，LCE在3 ~ 72天的等待期进行。第二组:行LCE且无胆囊引流的患者(n=35)。根据等待时间将第一组患者分为3个亚组:A组- LCE在PTCS后10天内进行，B组- LCE在PTCS后2 ~ 4周进行(n=12)， C组，LCE在PTCS后4周进行。分析术前、术中资料及术后并发症。结果。根据术前资料，两组患者体温、实验室资料及伴发疾病无明显差异。仅在患者年龄方面存在统计学差异(65.3±9.0 vs 53.4±15.4)。LCE第二组手术时间较第一组更长，但差异无统计学意义(108.1±30.5 vs 117.9±39.9)。LCE术后并发症5例(14.2%)，出血4例(11.4%)，术后创面化脓1例(2.8%)。术中10例(15.6%)患者行胆总管转换，1例(1.5%)患者术中胆总管壁损伤。A、B、c组间差异无统计学意义。采用两阶段治疗可显著减少转开腹手术，显著减少术后并发症和术后住院时间。根据我们的研究结果，PTCS和LCE的最佳间隔时间为4周以上。
{"title":"EFFICACY OF PERCUTANEOUS TRANSHEPATIC CHOLECYSTOSTOMY IN ACUTEOBSTRUCTIVE CHOLECYSTITIS","authors":"Zh.R Ospan, M. Doskhanov, E. Serikuly, D. Mukazhanov, A.A. Hadjieva, S. Tileuov, A. Skakbayev, B. Askeev, Zhasulan Baimakhanov, S. Kaniyev, A. Chormanov, B. Baimakhanov, M. Seisembayev","doi":"10.35805/bsk2022iv005","DOIUrl":"https://doi.org/10.35805/bsk2022iv005","url":null,"abstract":"Acute obstructive cholecystitis is a common disease with a significant risk of mortality and complications. Active surgical tactics, such as open and laparoscopic access, pose a significant risk for elderly patients with concomitant diseases on the background of acute cholecystitis. The aim of our study is to analyze the effectiveness of percutaneous transhepatic cholecystostomy (PTCS) in acute obstructive cholecystitis (AOC) and subsequent laparoscopic cholecystectomy (LCE). Materials and methods. Retrospectively, we analyzed 64 patients treated with AOC in the period from 2017 to 2021 at the NSCS named after A.N. Syzganov. We divided them into 2 groups depending on surgical treatment. The first group: patients who were performedPTCS (n=29) at the first stage. The second stage, LCE was performed during the waiting period from 3 days to 72 days. The second group: patients who underwent LCE without drainage of the gallbladder (n=35). Also, the patients of the first group were divided into 3 subgroups depending on the waiting time: group A - LCE was performed within 10 days after PTCS, subgroup B - LCE was performed after from 2 to 4 weeks (n=12), patients of the subgroup C, LCE were performed after 4 weeks after PTCS. Preoperative, intraoperative data and postoperative complications were analyzed. Results. According to preoperative data, there was no significant difference in body temperature, laboratory data and concomitant diseases. The statistical difference was revealed only in the age of patients (65.3±9.0 vs 53.4±15.4). The duration of the operation in the second group of LCE was longer compared to the first group, but no significant difference was detected (108.1 ± 30.5 vs 117.9 ± 39.9). In the postoperative period after LCE, complications were observed in 5 (14.2%) cases: bleeding in 4 (11.4%) cases and suppuration of the postoperative wound in 1 (2.8%) case. Conversion was performed in 10 (15.6%) cases, and in one (1.5%) case, the choledochal wall was injured intraoperatively. There was no significant difference between groups A, B and C. Conclusion.The use of two-stage treatment significantly reduces the conversion to open surgery, significantly reduces postoperative complications and hospital stay in the postoperative period. According to the results of our research, the most optimal interval between PTCS and LCE is a period of more than 4 weeks.","PeriodicalId":197118,"journal":{"name":"BULLETIN OF SURGERY IN KAZAKHSTAN","volume":"143 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132376505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Nagasbekov, Zhasulan Baimakhanov, E. Nurlanbayev, S. Kaniyev, A. Chormanov, B. Baimakhanov
Liver echinococcosis is a severe zoonotic disease of cosmopolitan nature caused by cestodes of the genus Echinococcus from the family Taeniidae that leads to cystic and alveolar echinococcosis that forms a significant problem in public health worldwide. The purpose of this work is to analyze a literary review of modern approaches in the diagnostics and treatment of liver cystous echinococcosis Material and methods. We systematically searched the literature and selected sources from MEDLINE, PubMed, Scopus, Elsevier, E-library, Google Scholar as well as research papers and online educational publications in various languages. Forty three papers that met the inclusion criteria were included. Results. The review article presents epidemiology, methods of diagnosis and treatment of cystic liver echinococcus. Conclusion. Thus, among the modern approaches in diagnostics of cystic liver echinococcosis, ultrasound is the method of choice, also CT, MRI, ERCP are methods used for identifying complications. Morever, various surgical methods in combination with antiparasitic therapy decrease the risk and recurrence of cystic liver echinococcosis.
{"title":"MODERN APPROACHES IN THE DIAGNOSTICS AND TREATMENT OF CYSTIC LIVER ECHINOCOCCOSIS. LITERATURE REVIEW","authors":"M. Nagasbekov, Zhasulan Baimakhanov, E. Nurlanbayev, S. Kaniyev, A. Chormanov, B. Baimakhanov","doi":"10.35805/bsk2022iv040","DOIUrl":"https://doi.org/10.35805/bsk2022iv040","url":null,"abstract":"Liver echinococcosis is a severe zoonotic disease of cosmopolitan nature caused by cestodes of the genus Echinococcus from the family Taeniidae that leads to cystic and alveolar echinococcosis that forms a significant problem in public health worldwide. The purpose of this work is to analyze a literary review of modern approaches in the diagnostics and treatment of liver cystous echinococcosis Material and methods. We systematically searched the literature and selected sources from MEDLINE, PubMed, Scopus, Elsevier, E-library, Google Scholar as well as research papers and online educational publications in various languages. Forty three papers that met the inclusion criteria were included. Results. The review article presents epidemiology, methods of diagnosis and treatment of cystic liver echinococcus. Conclusion. Thus, among the modern approaches in diagnostics of cystic liver echinococcosis, ultrasound is the method of choice, also CT, MRI, ERCP are methods used for identifying complications. Morever, various surgical methods in combination with antiparasitic therapy decrease the risk and recurrence of cystic liver echinococcosis.","PeriodicalId":197118,"journal":{"name":"BULLETIN OF SURGERY IN KAZAKHSTAN","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132036486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Kuatbekov, A. Egizekov, D.T. Musagaliev, T.V. Maslov, E.T. Sydykov, A. V. Mishin, N. Baizhigitov, B. Suieubekov
Tetralogy of Fallot (TOF) combined with major aortopulmonary collateral arteries (MAPCA) is a severe congenital heart defect due to the combination of a triad of cardiac malformation withan additional vascular anomaly of the small circulatory system. To date, there is no single accepted standard in which sequence and according to which criteria radical surgical correction of combined anomalies is indicated. This paper describes a clinical case of simultaneous opentreatment of TOF and endovascular occlusion of the MAPCA in an 8-month old child. Based onthe evidence base of a large study, our patient belonged to the group where after TOF correction the therapeutic way of MAPCA treatment was used at first, which was ineffective in 38% and led to surgical methods of MAPCA occlusion. Choosing the way of simultaneous simultaneoussurgical treatment of two pathologies allowed us to minimize postoperative risks and achievegoodclinical results.
{"title":"CLINICAL CASE OF SIMULTANEOUS RADICAL TREATMENT OF TETRALOGY OF FALLOT WITH MAJOR AORTOPULMONARY COLLATERAL ARTERIES","authors":"K. Kuatbekov, A. Egizekov, D.T. Musagaliev, T.V. Maslov, E.T. Sydykov, A. V. Mishin, N. Baizhigitov, B. Suieubekov","doi":"10.35805/bsk2022iv013","DOIUrl":"https://doi.org/10.35805/bsk2022iv013","url":null,"abstract":"Tetralogy of Fallot (TOF) combined with major aortopulmonary collateral arteries (MAPCA) is a severe congenital heart defect due to the combination of a triad of cardiac malformation withan additional vascular anomaly of the small circulatory system. To date, there is no single accepted standard in which sequence and according to which criteria radical surgical correction of combined anomalies is indicated. This paper describes a clinical case of simultaneous opentreatment of TOF and endovascular occlusion of the MAPCA in an 8-month old child. Based onthe evidence base of a large study, our patient belonged to the group where after TOF correction the therapeutic way of MAPCA treatment was used at first, which was ineffective in 38% and led to surgical methods of MAPCA occlusion. Choosing the way of simultaneous simultaneoussurgical treatment of two pathologies allowed us to minimize postoperative risks and achievegoodclinical results.","PeriodicalId":197118,"journal":{"name":"BULLETIN OF SURGERY IN KAZAKHSTAN","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133985013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Tajibayev, A. Baubekov, V. Madyarov, I. Sagatov, O.Zh. Shulenbayev, A.E. Karassayeva, D.E. Aidarov, A.E. Aidarov, M. Khanchi, A. Saduakas
Central venous catheters (CVCs), such as the tunneled catheters and the totally implanted ports, play a major role in general medicine and oncology. Thrombosis associated with CVCs is a common complication in cancer patients. Thus, in order to more widely study the problem of catheter-associated thrombosis in cancer patients, we initiated a study for 2022-2023 within one region. Purpose. Evaluation of the efficacy and safety of thromboprophylaxis of catheter-associated thrombosis with rivaroxaban in cancer patients. Material and methods. Prospective multicenter study, conducted since 01/05/2022 and planned to be completed by the end of 2022, on the basis of three centers. The subjects are divided into 2 groups to randomize 60 participants in each. The first group: receive DOACs (rivaroxaban) at a dosage of 20 mg per day the day before the inserting of the CVC. Second group: treatment of the underlying disease without the use of DOACs. Results. None of the patients developed submassive or massive pulmonary embolism. There were no cases of CAT in the thromboprophylaxis group compared to the non-thrombotic prophylaxis group (0% vs 15.7%). The relative risk of developing CAT is 0.86, which indicates the effectiveness of thromboprophylaxis with rivaroxaban. Conclusion. Our interim results show the efficacy of rivaroxaban at a dosage of 20 mg per day in cancer patients. The final results are planned to be published at the end of the study
中心静脉导管(CVCs)在普通医学和肿瘤学中发挥着重要的作用，包括隧道式导管和全植入式导管。cvc相关血栓形成是癌症患者常见的并发症。因此，为了更广泛地研究癌症患者导管相关血栓形成问题，我们在一个地区启动了2022-2023年的研究。目的。评价利伐沙班预防癌症患者导管相关血栓形成的有效性和安全性。材料和方法。前瞻性多中心研究，自2022年5月1日开始，计划于2022年底完成，以三个中心为基础。受试者被分为两组，每组随机分配60名参与者。第一组:在植入CVC的前一天接受DOACs(利伐沙班)，剂量为20mg /天。第二组:治疗基础疾病，不使用doac。结果。没有患者出现亚块状或块状肺栓塞。与非血栓预防组相比，血栓预防组没有CAT病例(0% vs 15.7%)。发生CAT的相对危险度为0.86，表明利伐沙班预防血栓的有效性。结论。我们的中期结果显示利伐沙班每天20mg的剂量对癌症患者有效。最终结果计划在研究结束时公布
{"title":"PROPHYLAXIS WITH RIVOROXABAN OF CATHETER ASSOCIATED THROMBOSIS IN CANCER PATIENTS (CAT-RIVO TRIAL): MAIN DATA AND INTERMEDIATE RESULTS OF PROSPECTIVE MULTICENTER STUDY","authors":"T. Tajibayev, A. Baubekov, V. Madyarov, I. Sagatov, O.Zh. Shulenbayev, A.E. Karassayeva, D.E. Aidarov, A.E. Aidarov, M. Khanchi, A. Saduakas","doi":"10.35805/bsk2022iv060","DOIUrl":"https://doi.org/10.35805/bsk2022iv060","url":null,"abstract":"Central venous catheters (CVCs), such as the tunneled catheters and the totally implanted ports, play a major role in general medicine and oncology. Thrombosis associated with CVCs is a common complication in cancer patients. Thus, in order to more widely study the problem of catheter-associated thrombosis in cancer patients, we initiated a study for 2022-2023 within one region. Purpose. Evaluation of the efficacy and safety of thromboprophylaxis of catheter-associated thrombosis with rivaroxaban in cancer patients. Material and methods. Prospective multicenter study, conducted since 01/05/2022 and planned to be completed by the end of 2022, on the basis of three centers. The subjects are divided into 2 groups to randomize 60 participants in each. The first group: receive DOACs (rivaroxaban) at a dosage of 20 mg per day the day before the inserting of the CVC. Second group: treatment of the underlying disease without the use of DOACs. Results. None of the patients developed submassive or massive pulmonary embolism. There were no cases of CAT in the thromboprophylaxis group compared to the non-thrombotic prophylaxis group (0% vs 15.7%). The relative risk of developing CAT is 0.86, which indicates the effectiveness of thromboprophylaxis with rivaroxaban. Conclusion. Our interim results show the efficacy of rivaroxaban at a dosage of 20 mg per day in cancer patients. The final results are planned to be published at the end of the study","PeriodicalId":197118,"journal":{"name":"BULLETIN OF SURGERY IN KAZAKHSTAN","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122559301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V.G. Semenov, N.K. Tazhimuratov, R. Baudunov, D.K. Zhamashev, A.K. Khamidolla
This article summarizes a small experience in the treatment of dislocations of the patella by arthroscopic method. In total, from 2018 to 2021,450arthroscopic operations have been performed by us on the knee joint, of which number of stabilization of the patella in case of dislocation was 7. Thus, we performed 4 operations with primary traumatic dislocation, and with the usual - 3. We consider it has justified toeliminate the dislocation of the patella by a minimally invasive method, i.e. via arthroscopy, which allows to restore the biomechanical axis with the elimination of dislocation of the patella simultaneously or sequentially at the stage of treatment and provides the best expected results.
{"title":"OUR EXPERIENCE IN THE TREATMENT OF DISLOCATION OF THE PATELLA BY A MINIMALLY INVASIVE TECHNIQUE","authors":"V.G. Semenov, N.K. Tazhimuratov, R. Baudunov, D.K. Zhamashev, A.K. Khamidolla","doi":"10.35805/bsk2022iv030","DOIUrl":"https://doi.org/10.35805/bsk2022iv030","url":null,"abstract":"This article summarizes a small experience in the treatment of dislocations of the patella by arthroscopic method. In total, from 2018 to 2021,450arthroscopic operations have been performed by us on the knee joint, of which number of stabilization of the patella in case of dislocation was 7. Thus, we performed 4 operations with primary traumatic dislocation, and with the usual - 3. We consider it has justified toeliminate the dislocation of the patella by a minimally invasive method, i.e. via arthroscopy, which allows to restore the biomechanical axis with the elimination of dislocation of the patella simultaneously or sequentially at the stage of treatment and provides the best expected results.","PeriodicalId":197118,"journal":{"name":"BULLETIN OF SURGERY IN KAZAKHSTAN","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129674227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Kuatbekov, A. Egizekov, A. V. Mishin, N. Baizhigitov, B. Suieubekov, A. Nurbekov
Sinus venosus defectis an unusual type of interatrial communication and is almost always combined with partial abnormal pulmonary vein drainage (PAPVD) into the superior venacava (SVC) or right atrium (RA). Different types of venous outflow through the vena cava occur: the presence of an additional left vena cava with different drainage loci to both right and left atriaor, as in our case, the dominant unpaired vein directly draining into the right atrium with outprior communication with the superior right vena cava. This paper describes a clinical case of radical correction of partial anomalous pulmonary vein drainage combined with sinus venosus atrial septal defect (ASD) in a 14-year-old child with dominant venous outflow from the upper half of the body via innominate vein, by combined biplasty from auto pericardial patches, showing adequate upper-venous outflow under cardiopulmonary bypass. It is necessary to provide clear information about congenital heart disease and optimal timing of its surgical correction to a wide audience, not only to the professional medical community, but importantly, to the entire population of the Republic. The provision of publicly available professional information should be highlighted on the official websites of clinics and all available media opportunities, where parents and patients could be fully acquainted with the specific soft entire treatment processing an accessible and convenient information platform.
{"title":"CLINICAL CASE OF BIPLASTIC CORRECTION OF ABNORMAL PULMONARY VEIN DRAINAGE WITH SINUS VENOSUS DEFECT IN A DOMINANT INNOMINATE VEIN IN ADOLESCENCE","authors":"K. Kuatbekov, A. Egizekov, A. V. Mishin, N. Baizhigitov, B. Suieubekov, A. Nurbekov","doi":"10.35805/bsk2022iii021","DOIUrl":"https://doi.org/10.35805/bsk2022iii021","url":null,"abstract":"Sinus venosus defectis an unusual type of interatrial communication and is almost always combined with partial abnormal pulmonary vein drainage (PAPVD) into the superior venacava (SVC) or right atrium (RA). Different types of venous outflow through the vena cava occur: the presence of an additional left vena cava with different drainage loci to both right and left atriaor, as in our case, the dominant unpaired vein directly draining into the right atrium with outprior communication with the superior right vena cava. This paper describes a clinical case of radical correction of partial anomalous pulmonary vein drainage combined with sinus venosus atrial septal defect (ASD) in a 14-year-old child with dominant venous outflow from the upper half of the body via innominate vein, by combined biplasty from auto pericardial patches, showing adequate upper-venous outflow under cardiopulmonary bypass. It is necessary to provide clear information about congenital heart disease and optimal timing of its surgical correction to a wide audience, not only to the professional medical community, but importantly, to the entire population of the Republic. The provision of publicly available professional information should be highlighted on the official websites of clinics and all available media opportunities, where parents and patients could be fully acquainted with the specific soft entire treatment processing an accessible and convenient information platform.","PeriodicalId":197118,"journal":{"name":"BULLETIN OF SURGERY IN KAZAKHSTAN","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123786421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Meherremov, M. Muradov, Y.A. Imirov, G.Zh. Seilkhanova, Y.N. Nabiyev, M. Karimov, N.S. Akhmetov
The human hand is an organ of labor, self-service, touch. According to Kaplan E.V. the hand is an extension of our brain in the environment around us. However, being one of the most functionally loaded systems, the hand and its bone segments are damaged quite often. The purpose of this work is to analyze a literary review of modern prostheses in the treatment of diseases of the bones and joints of the hand. Material and methods. We systematically searched the literature and selected sources from MEDLINE, Cochrane databases, Google Scholar, PubMed, as well as research papers and online educational publications in English and Russian. Forty papers that met the inclusion criteria were included. Results. The review article presents methods of treating patients with defects and injuries of the bones and joints of the hand, the causes of the development of this pathological condition. Conclusion. Thus, the existing types of prostheses currently do not fully meet the needs of patients and do not have a 100% positive effect from their use in modern reconstructive surgery. The number of unsatisfactory results of reconstructive operations and disability rates remain high.
{"title":"NEW WAYS TO SOLUTION PROSTHETICS FOR EXTENSIVE DEFECTS OF THE JOINTS AND BONES OF THE HAND (LITERATURE REVIEW)","authors":"D. Meherremov, M. Muradov, Y.A. Imirov, G.Zh. Seilkhanova, Y.N. Nabiyev, M. Karimov, N.S. Akhmetov","doi":"10.35805/bsk2022iii005","DOIUrl":"https://doi.org/10.35805/bsk2022iii005","url":null,"abstract":"The human hand is an organ of labor, self-service, touch. According to Kaplan E.V. the hand is an extension of our brain in the environment around us. However, being one of the most functionally loaded systems, the hand and its bone segments are damaged quite often. The purpose of this work is to analyze a literary review of modern prostheses in the treatment of diseases of the bones and joints of the hand. Material and methods. We systematically searched the literature and selected sources from MEDLINE, Cochrane databases, Google Scholar, PubMed, as well as research papers and online educational publications in English and Russian. Forty papers that met the inclusion criteria were included. Results. The review article presents methods of treating patients with defects and injuries of the bones and joints of the hand, the causes of the development of this pathological condition. Conclusion. Thus, the existing types of prostheses currently do not fully meet the needs of patients and do not have a 100% positive effect from their use in modern reconstructive surgery. The number of unsatisfactory results of reconstructive operations and disability rates remain high.","PeriodicalId":197118,"journal":{"name":"BULLETIN OF SURGERY IN KAZAKHSTAN","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116036800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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