Tetralogy of Fallot (TоF) is a congenital heart disease that includes ventricular septal defect (VSD), right ventricular outflow tract obstruction, aortic root dextraposition, and right ventricular hypertrophy. TоF occurs in 3 out of 10,000 live births and accounts for 7–10% of all congenital heart defects. The etiology of TоF is multifactorial and may include untreated maternal diabetes, phenylketonuria, and retinoic acid intake. Associated chromosomal abnormalities include trisomies 21, 18, and 13, but recent studies indicate a much higher association with microdeletion of chromosome 22. The familial risk of TоF is 3%. The article presents the results of scientific publications about ToF. In particular, modern and topical issues of genetic predisposition, morphology, diagnosis, indications for surgical treatment, including radical and staged, are considered.
{"title":"TETRALOGY OF FALLOT: MODERN DATA. REVIEW OF LITERATURE","authors":"I. Sagatov, A. V. Sapunov","doi":"10.35805/bsk2022ii026","DOIUrl":"https://doi.org/10.35805/bsk2022ii026","url":null,"abstract":"Tetralogy of Fallot (TоF) is a congenital heart disease that includes ventricular septal defect (VSD), right ventricular outflow tract obstruction, aortic root dextraposition, and right ventricular hypertrophy. TоF occurs in 3 out of 10,000 live births and accounts for 7–10% of all congenital heart defects. The etiology of TоF is multifactorial and may include untreated maternal diabetes, phenylketonuria, and retinoic acid intake. Associated chromosomal abnormalities include trisomies 21, 18, and 13, but recent studies indicate a much higher association with microdeletion of chromosome 22. The familial risk of TоF is 3%. The article presents the results of scientific publications about ToF. In particular, modern and topical issues of genetic predisposition, morphology, diagnosis, indications for surgical treatment, including radical and staged, are considered.","PeriodicalId":197118,"journal":{"name":"BULLETIN OF SURGERY IN KAZAKHSTAN","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131432139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Increasement in the diameter of the thoracic aorta ≥ 50% of the norm of 40 mm in men and 34 mm in women (99 percentile) is considered to be an aneurysmal expansion. The risk of rupture is proportional to the size of the aneurysm and is associated with the development of fatal complications. Diagnosis is usually verified by computed tomographic angiography (CTA), magnetic resonance angiography (MRA), or transesophageal echocardiogram. Treatment consists of endovascular stent graft placement or open surgery in combination with optimal medical therapy. The article presents the experience of treating a patient with a dissecting aneurysm of the thoracic aorta type IIIB according to DeBakey using a stent graft modified by a doctor “on table” by forming a fenestration modeled after the anatomy of the left subclavian artery orifice. The aim of the work was to evaluate the short-term and medium-term results and prognosis of treatment using the technique of endovascular prosthesis with a modified graft. Such modifications on the table or in situ make it possible to model the prosthesis according to the variant of the anatomy of a particular patient, which allows optimizing the apposition of the prosthesis, eliminating additional stages of complex surgical treatment, reducing the undesirable effects of standard approaches, including preliminary endovascular occlusion of the left subclavian artery and/or the formation of a carotid-subclavian shunt, reduce the time of stationary observation. The use of the described technique will reduce the radicalness of surgical treatment of patients with dissecting aneurysms and increase economic efficiency. This technique is a promising direction in the development of endovascular and surgery and requires further study to assess long-term results and prognosis in a large number of patients.
{"title":"PHYSICIAN MODIFIED ENDOVASCULAR STENT-GRAFT IN PATIENT WITH DISSECTING THORACIC AORTIC ANEURYSM. CASE REPORT","authors":"A. V. Sapunov, I. Sagatov, B. Ormanov","doi":"10.35805/bsk2022ii019","DOIUrl":"https://doi.org/10.35805/bsk2022ii019","url":null,"abstract":"Increasement in the diameter of the thoracic aorta ≥ 50% of the norm of 40 mm in men and 34 mm in women (99 percentile) is considered to be an aneurysmal expansion. The risk of rupture is proportional to the size of the aneurysm and is associated with the development of fatal complications. Diagnosis is usually verified by computed tomographic angiography (CTA), magnetic resonance angiography (MRA), or transesophageal echocardiogram. Treatment consists of endovascular stent graft placement or open surgery in combination with optimal medical therapy. The article presents the experience of treating a patient with a dissecting aneurysm of the thoracic aorta type IIIB according to DeBakey using a stent graft modified by a doctor “on table” by forming a fenestration modeled after the anatomy of the left subclavian artery orifice. The aim of the work was to evaluate the short-term and medium-term results and prognosis of treatment using the technique of endovascular prosthesis with a modified graft. Such modifications on the table or in situ make it possible to model the prosthesis according to the variant of the anatomy of a particular patient, which allows optimizing the apposition of the prosthesis, eliminating additional stages of complex surgical treatment, reducing the undesirable effects of standard approaches, including preliminary endovascular occlusion of the left subclavian artery and/or the formation of a carotid-subclavian shunt, reduce the time of stationary observation. The use of the described technique will reduce the radicalness of surgical treatment of patients with dissecting aneurysms and increase economic efficiency. This technique is a promising direction in the development of endovascular and surgery and requires further study to assess long-term results and prognosis in a large number of patients.","PeriodicalId":197118,"journal":{"name":"BULLETIN OF SURGERY IN KAZAKHSTAN","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131603097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Kazantayev, Y. Nabiev, M. Muradov, K. Muhamedkerim
Objective. Assessment of long-term results of surgical treatment of closed ruptures of the extensor tendons of the hand according to the method used in the clinic of JSC National Scientific Center for Surgery named after A.N. Syzganov (Innovation patent number: 19373). Material and methods. From 2020 to 2022, 149 patients were operated on the basis of the “A.N. Syzganov National Scientific Center of Surgery” JSC. The age of patients ranged from 17 to 68 (mean age 36±12) years, men were 84 (57%), women – 65 (43%), 115 patients had fresh damage, 34 patients had long–standing damage to the extensor tendons of the hand in the I-zone. 87 people had an injury on the right hand, 62 on the left. Results. According to the criterion of distal phalanx extension deficiency (V. I. Rozov), only 13 (46.5%) patients had excellent results: complete flexion – 25 distal phalanx extension. In 15 (53.5%) cases, there were poor results: a deficit of distal phalanx extension from 7 to 32°. According to the results of the DASH questionnaire, the situation is somewhat better: 21.3% ±5. Conclusion. In this article, it is possible to use the improved Cuneo tendon suture. In 149 patients with tendon injuries with reflectors, we received the award of the proposed suture. The use of a modified tendon suture makes it possible to increase the surface slip in the observation zone, which opens the exit of the tendon through the bone-fibrous canal and the significant trauma of the surgical operation and the duration of the operation.
目标。根据以A.N. Syzganov命名的JSC国家外科科学中心临床使用的方法(创新专利号:19373)手术治疗手部伸肌腱闭合性断裂的长期效果评估。材料和方法。从2020年到2022年，149例患者在“A.N.”的基础上进行了手术Syzganov国家外科科学中心(JSC)患者年龄17 ~ 68岁(平均年龄36±12岁)，男性84例(57%)，女性65例(43%)，新发损伤115例，i区伸肌腱长期损伤34例。87人的右手受伤，62人的左手受伤。结果。根据远端指骨伸展不足标准(V. I. Rozov)，只有13例(46.5%)患者获得优异的结果:完全屈曲-远端指骨伸展25例。在15例(53.5%)病例中，结果不佳:远端指骨伸展缺损从7°到32°。根据DASH问卷调查结果，情况略好:21.3%±5%。结论。在本文中，可以使用改良的Cuneo肌腱缝合。在149例肌腱损伤患者中，我们获得了建议缝合的奖励。使用改良的肌腱缝合可以增加观察区的表面滑移，从而打开肌腱通过骨纤维管的出口，并增加外科手术的重大创伤和手术时间。
{"title":"THE RESULTS OF SURGICAL TREATMENT IN THE CONSEQUENCES OF INJURIES OF THE TENDONS OF THE HAND","authors":"K. Kazantayev, Y. Nabiev, M. Muradov, K. Muhamedkerim","doi":"10.35805/bsk2022ii010","DOIUrl":"https://doi.org/10.35805/bsk2022ii010","url":null,"abstract":"Objective. Assessment of long-term results of surgical treatment of closed ruptures of the extensor tendons of the hand according to the method used in the clinic of JSC National Scientific Center for Surgery named after A.N. Syzganov (Innovation patent number: 19373). Material and methods. From 2020 to 2022, 149 patients were operated on the basis of the “A.N. Syzganov National Scientific Center of Surgery” JSC. The age of patients ranged from 17 to 68 (mean age 36±12) years, men were 84 (57%), women – 65 (43%), 115 patients had fresh damage, 34 patients had long–standing damage to the extensor tendons of the hand in the I-zone. 87 people had an injury on the right hand, 62 on the left. Results. According to the criterion of distal phalanx extension deficiency (V. I. Rozov), only 13 (46.5%) patients had excellent results: complete flexion – 25 distal phalanx extension. In 15 (53.5%) cases, there were poor results: a deficit of distal phalanx extension from 7 to 32°. According to the results of the DASH questionnaire, the situation is somewhat better: 21.3% ±5. Conclusion. In this article, it is possible to use the improved Cuneo tendon suture. In 149 patients with tendon injuries with reflectors, we received the award of the proposed suture. The use of a modified tendon suture makes it possible to increase the surface slip in the observation zone, which opens the exit of the tendon through the bone-fibrous canal and the significant trauma of the surgical operation and the duration of the operation.","PeriodicalId":197118,"journal":{"name":"BULLETIN OF SURGERY IN KAZAKHSTAN","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127950714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Most of the classification of pancreatic epithelial tumors in the 5th edition remains unchanged from the previous edition. In the new classification, precancerous lesions are classified according to two levels of dysplasia. Intraductal papillary tumors and intraductal papillary tumors associated with invasive carcinoma are separated from the other subtypes. Some changes have occurred in the TNM classification.
{"title":"NEW IN THE CLASSIFICATION OF PANCREATIC EPITHELIAL TUMORS (WHO, 2019, 5TH EDITION)","authors":"V. Grinberg, E. Enin","doi":"10.35805/bsk2022ii047","DOIUrl":"https://doi.org/10.35805/bsk2022ii047","url":null,"abstract":"Most of the classification of pancreatic epithelial tumors in the 5th edition remains unchanged from the previous edition. In the new classification, precancerous lesions are classified according to two levels of dysplasia. Intraductal papillary tumors and intraductal papillary tumors associated with invasive carcinoma are separated from the other subtypes. Some changes have occurred in the TNM classification.","PeriodicalId":197118,"journal":{"name":"BULLETIN OF SURGERY IN KAZAKHSTAN","volume":"3 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131688546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Yerimova, B. Shirtaev, M. Sundetov, D.O. Bogdanova, S. Mukashev, А.М. Anarbayeva
These days, the “craze” for antibiotics has become like an epidemic and today, antibiotic resistance is a global problem. Objective.To study antibiotic resistance in children before and after surgery. Material and methods: Since March 2016, 32 liver transplants have been performed in children (from 6 months to 8 years). Of these, 23 (78.1%) patients with biliary atresia, 2 (6.2%) with cirrhosis of the liver in the outcome of autoimmune hepatitis, 1 (3.1%) with primary hyperoxaluria, 1 (3.1%) with cholangiocarcinoma, 1 (3,1%), 1 (3,1%) with inoperable hepatoblastoma, 1 (3.1%) cirrhosis of the liver in the outcome of viral hepatitis C . The number of girls was 17 (53.1%) and boys 15 (46.9%). Results:There was a 100% antibiotic intake in the preoperative period.When cross-testing design, 5 (15.6%) children with Klebsiella sepsis and with a fatal outcome were resistant to all groups of antibacterial drugs. Ethical issues: The study was conducted in accordance with the current version of the Declaration of Helsinki, in accordance with the Standard of Good Clinical Practice (GCP) (Appendix 2 to the order of the Acting Minister of Health of the Republic of Kazakhstan dated February 4, 2021 No. RK DSM-15). Conclusion. Antibiotic resistance is a major threat to global health and sustainable development, the principles of which were defined in the 2030 Agenda and the Sustainable Development Goals. It is estimated that, in the absence of effective interventions, the development of antimicrobial resistance could lead to a global death’s will increase by about 10 million cases annually. Growing concerns about antibiotic resistance have led to the adoption of a number of national, regional and global action plans in recent years to raise awareness, promote research and optimize antimicrobial use and access. Global initiatives also highlight the importance of more effective and sustainable investment in technology development and intersectoral action.
{"title":"PROBLEMS OF ANTIBIOTIC RESISTANCE IN CHILDREN AFTER LIVER TRANSPLANTATION","authors":"N. Yerimova, B. Shirtaev, M. Sundetov, D.O. Bogdanova, S. Mukashev, А.М. Anarbayeva","doi":"10.35805/bsk2022ii037","DOIUrl":"https://doi.org/10.35805/bsk2022ii037","url":null,"abstract":"These days, the “craze” for antibiotics has become like an epidemic and today, antibiotic resistance is a global problem. Objective.To study antibiotic resistance in children before and after surgery. Material and methods: Since March 2016, 32 liver transplants have been performed in children (from 6 months to 8 years). Of these, 23 (78.1%) patients with biliary atresia, 2 (6.2%) with cirrhosis of the liver in the outcome of autoimmune hepatitis, 1 (3.1%) with primary hyperoxaluria, 1 (3.1%) with cholangiocarcinoma, 1 (3,1%), 1 (3,1%) with inoperable hepatoblastoma, 1 (3.1%) cirrhosis of the liver in the outcome of viral hepatitis C . The number of girls was 17 (53.1%) and boys 15 (46.9%). Results:There was a 100% antibiotic intake in the preoperative period.When cross-testing design, 5 (15.6%) children with Klebsiella sepsis and with a fatal outcome were resistant to all groups of antibacterial drugs. Ethical issues: The study was conducted in accordance with the current version of the Declaration of Helsinki, in accordance with the Standard of Good Clinical Practice (GCP) (Appendix 2 to the order of the Acting Minister of Health of the Republic of Kazakhstan dated February 4, 2021 No. RK DSM-15). Conclusion. Antibiotic resistance is a major threat to global health and sustainable development, the principles of which were defined in the 2030 Agenda and the Sustainable Development Goals. It is estimated that, in the absence of effective interventions, the development of antimicrobial resistance could lead to a global death’s will increase by about 10 million cases annually. Growing concerns about antibiotic resistance have led to the adoption of a number of national, regional and global action plans in recent years to raise awareness, promote research and optimize antimicrobial use and access. Global initiatives also highlight the importance of more effective and sustainable investment in technology development and intersectoral action.","PeriodicalId":197118,"journal":{"name":"BULLETIN OF SURGERY IN KAZAKHSTAN","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122988174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Madadov, E. Belgibaev, Zh.M. Syrymov, E. Nabiev, B.G. Rgebaev, N. Saduakas
bstract Objective. Assess advantages and disadvantages of retroperitoneoscopic access for the resection of renal cysts in clinical practice. Material and methods. For the period from 01/09/2020 tо 30/11/2021, in our center we performed 25 retroperitoneal endoscopic resections of renal cysts. Access was made through Lesgaft-Grunfield triangle. All patients underwent standard clinical evaluation for renal cysts. Results. Retroperitoneal access was performed for all patients by standard technique. All surgeries were finished without conversion to open surgery. Mean duration of surgery was 25,45 ± 2,55 min. Mean intraoperative blood loss was 20,4 ± 0,6 ml. Intra – andpostoperativecomplications, that required extra interventions were not encountered. Meanhospital – instaywas 4,6 ± 0,4 days and patients soon after discharge returned to their daily activities. All patients were under follow-up to 12 months. Conclusion. Retroperitoneal endoscopic access is a good alternative for laparoscopic access for surgical treatment of renal cysts, with less trauma and with no invasion into peritoneal cavity. Timeofrecoveryisthesame aswithlaparoscopy. This technique is also carries good cosmetic effect. One of main advantages is that in this access it is possible to hold high CO2 pressure, that is particularly in patients with ischemic heart disease is undesirable to hold high intraabdominal pressure
{"title":"RETROPERITONEOSCOPIC EXCISION OF SIMPLE KIDNEY CYSTS; ADVANTAGES AND DISADVANTAGES - OUR EXPERIENCE","authors":"I. Madadov, E. Belgibaev, Zh.M. Syrymov, E. Nabiev, B.G. Rgebaev, N. Saduakas","doi":"10.35805/bsk2022ii005","DOIUrl":"https://doi.org/10.35805/bsk2022ii005","url":null,"abstract":"bstract Objective. Assess advantages and disadvantages of retroperitoneoscopic access for the resection of renal cysts in clinical practice. Material and methods. For the period from 01/09/2020 tо 30/11/2021, in our center we performed 25 retroperitoneal endoscopic resections of renal cysts. Access was made through Lesgaft-Grunfield triangle. All patients underwent standard clinical evaluation for renal cysts. Results. Retroperitoneal access was performed for all patients by standard technique. All surgeries were finished without conversion to open surgery. Mean duration of surgery was 25,45 ± 2,55 min. Mean intraoperative blood loss was 20,4 ± 0,6 ml. Intra – andpostoperativecomplications, that required extra interventions were not encountered. Meanhospital – instaywas 4,6 ± 0,4 days and patients soon after discharge returned to their daily activities. All patients were under follow-up to 12 months. Conclusion. Retroperitoneal endoscopic access is a good alternative for laparoscopic access for surgical treatment of renal cysts, with less trauma and with no invasion into peritoneal cavity. Timeofrecoveryisthesame aswithlaparoscopy. This technique is also carries good cosmetic effect. One of main advantages is that in this access it is possible to hold high CO2 pressure, that is particularly in patients with ischemic heart disease is undesirable to hold high intraabdominal pressure","PeriodicalId":197118,"journal":{"name":"BULLETIN OF SURGERY IN KAZAKHSTAN","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129189149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Varicocele is a pathology characterized by dilation of the venous veins of the seminal canal. Currently, the incidence of varicocele among adolescent men aged 12-20 years is 10-20%, and among men suffering from infertility, it is detected in 45%. In clinical practice, there are several methods of treating varicocele: open or microsurgical laparotomy, surgical embolization and laparoscopic varicocelectomy. However, the frequency of relapses of varicocele varies and depends on the method of its treatment. Embolization performed using venography helps to accurately determine the condition of the vessels of the testicles. Therefore, in our article we will describe the advantages and possibilities of modern minimally invasive treatment of varicocele embolization, possible complications and results.
{"title":"ENDOVASCULAR EMBOLIZATION OF THE TESTICULAR VEIN DURING VARICOCELE. CLINICAL CASE","authors":"M. Ramazanov, S. Anartaev, A.B. Berkinbay","doi":"10.35805/bsk2022ii014","DOIUrl":"https://doi.org/10.35805/bsk2022ii014","url":null,"abstract":"Varicocele is a pathology characterized by dilation of the venous veins of the seminal canal. Currently, the incidence of varicocele among adolescent men aged 12-20 years is 10-20%, and among men suffering from infertility, it is detected in 45%. In clinical practice, there are several methods of treating varicocele: open or microsurgical laparotomy, surgical embolization and laparoscopic varicocelectomy. However, the frequency of relapses of varicocele varies and depends on the method of its treatment. Embolization performed using venography helps to accurately determine the condition of the vessels of the testicles. Therefore, in our article we will describe the advantages and possibilities of modern minimally invasive treatment of varicocele embolization, possible complications and results.","PeriodicalId":197118,"journal":{"name":"BULLETIN OF SURGERY IN KAZAKHSTAN","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125855944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Гипертрофическая кардиомиопатия - распространенное наследственное заболевание сердца с неоднородной клинической картиной и естественным анамнезом. Последние достижения в методах диагностики и лечения сыграли важную роль в снижении частоты неблагоприятных клинических проявлений; однако полное устранение внезапной сердечной смерти по-прежнему остается недостижимым достижением. Несмотря на неоднородный клинический профиль и сложную патофизиологию, доступны эффективные стратегии лечения, включая, имплантируемые дефибрилляторы для предотвращения внезапной смерти, медикаментозную и хирургическую миэктомию (или, альтернативно, алкогольную абляцию перегородки) для облегчения обструкции оттока и симптомов сердечной недостаточности. А также фармакологические стратегии (и, возможно, радиочастотная абляция) для контроля фибрилляции предсердий и предотвращения эмболического инсульта. Теперь, по прошествии более чем 50 лет, гипертрофическая кардиомиопатия превратилась из редкого и в значительной степени неизлечимого заболевания в распространенное генетическое заболевание со стратегиями лечения, которые позволяют реалистично стремиться к восстановлению качества жизни и увеличению продолжительности жизни. В этой статье рассматриваются некоторые аспекты этого состояния: эпидемиология, клиника, диагностика и методика хирургического вмешательства. Цель исследования. Оценить эффективность хирургического лечения пациентов с гипертрофической кардиомиопатией. Материал и методы. Этот литературный обзор был выполнен в соответствии с заявлением PRISM. Базы данных, в которых проводился поиск в этом обзоре, включали базы данных Pubmed, Web of Science, Scopus и Cochrane для систематических обзоров. Заключение. Диагноз ГКМП основывается преимущественно на эхокардиографических переменных, включая динамические показатели ЛЖ, ВОЛЖ, распределение увеличенной толщины мышц, механизм и тяжесть МН, а также степень диастолической дисфункции.
{"title":"HYPERTROPHIC CARDIOMYOPATHY. LITERATURE REVIEW","authors":"I. Sagatov, B. Momynov","doi":"10.35805/bsk2022i025","DOIUrl":"https://doi.org/10.35805/bsk2022i025","url":null,"abstract":"Гипертрофическая кардиомиопатия - распространенное наследственное заболевание сердца с неоднородной клинической картиной и естественным анамнезом. Последние достижения в методах диагностики и лечения сыграли важную роль в снижении частоты неблагоприятных клинических проявлений; однако полное устранение внезапной сердечной смерти по-прежнему остается недостижимым достижением. Несмотря на неоднородный клинический профиль и сложную патофизиологию, доступны эффективные стратегии лечения, включая, имплантируемые дефибрилляторы для предотвращения внезапной смерти, медикаментозную и хирургическую миэктомию (или, альтернативно, алкогольную абляцию перегородки) для облегчения обструкции оттока и симптомов сердечной недостаточности. А также фармакологические стратегии (и, возможно, радиочастотная абляция) для контроля фибрилляции предсердий и предотвращения эмболического инсульта. Теперь, по прошествии более чем 50 лет, гипертрофическая кардиомиопатия превратилась из редкого и в значительной степени неизлечимого заболевания в распространенное генетическое заболевание со стратегиями лечения, которые позволяют реалистично стремиться к восстановлению качества жизни и увеличению продолжительности жизни. В этой статье рассматриваются некоторые аспекты этого состояния: эпидемиология, клиника, диагностика и методика хирургического вмешательства. Цель исследования. Оценить эффективность хирургического лечения пациентов с гипертрофической кардиомиопатией. Материал и методы. Этот литературный обзор был выполнен в соответствии с заявлением PRISM. Базы данных, в которых проводился поиск в этом обзоре, включали базы данных Pubmed, Web of Science, Scopus и Cochrane для систематических обзоров. Заключение. Диагноз ГКМП основывается преимущественно на эхокардиографических переменных, включая динамические показатели ЛЖ, ВОЛЖ, распределение увеличенной толщины мышц, механизм и тяжесть МН, а также степень диастолической дисфункции.","PeriodicalId":197118,"journal":{"name":"BULLETIN OF SURGERY IN KAZAKHSTAN","volume":"136 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115035859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Muradov, Y. Nabiev, K. Muhamedkerim, B. Baimakhanov, K. Kazantayev
In childhood, closing the pupil with the upper eyelid leads to the development of amblyopia in 20-70%. The main methods of surgical treatment of blepharoptosis in the absence of the function of the muscle that lifts the upper eyelid are suspension operations. Material and methods. A 2-year-old child presented with congenital ptosis of the right upper eyelid. Palpebral fissure versus right narrowed by 0.5 cm. Excursion of the left upper eyelid 0.9 cm, right 0.3 cm. After the written consent of the parents, the child underwent an operation to eliminate ptosis of the right upper eyelid by implantation parts of the superficial flexor of the hand. Results. The variety of suspension operations for blepharoptosis is associated not only with the many options for conducting a suspension suture (single and double diamond-shaped, triangular, U-shaped, etc.), but also with the materials used - biological and synthetic. Conclusion. According to our research, synthetic materials allow you to get a more stable good result, but we used a tendon.
{"title":"SURGICAL TREATMENT OF CONGENITAL PTOSIS OF THE UPPER EYELIDS","authors":"M. Muradov, Y. Nabiev, K. Muhamedkerim, B. Baimakhanov, K. Kazantayev","doi":"10.35805/bsk2022i021","DOIUrl":"https://doi.org/10.35805/bsk2022i021","url":null,"abstract":"In childhood, closing the pupil with the upper eyelid leads to the development of amblyopia in 20-70%. The main methods of surgical treatment of blepharoptosis in the absence of the function of the muscle that lifts the upper eyelid are suspension operations. Material and methods. A 2-year-old child presented with congenital ptosis of the right upper eyelid. Palpebral fissure versus right narrowed by 0.5 cm. Excursion of the left upper eyelid 0.9 cm, right 0.3 cm. After the written consent of the parents, the child underwent an operation to eliminate ptosis of the right upper eyelid by implantation parts of the superficial flexor of the hand. Results. The variety of suspension operations for blepharoptosis is associated not only with the many options for conducting a suspension suture (single and double diamond-shaped, triangular, U-shaped, etc.), but also with the materials used - biological and synthetic. Conclusion. According to our research, synthetic materials allow you to get a more stable good result, but we used a tendon.","PeriodicalId":197118,"journal":{"name":"BULLETIN OF SURGERY IN KAZAKHSTAN","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131713594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Shirtaev, N. Yerimova, M. Sundetov, K. Khalykov, D. Kurbanov, A. Akhbetova, S. Akilbekov, S. Mukashev, A. Kanazov, D. Bogdanova
The article reflects the role of non-steroidal anti-inflammatory drugs in postoperative period. The study was conducted on the data of 94 operations of children aged from 10 months to 15 years (mean age 4.4 years). All patients of our center with esophagocoloplasty in the postoperative period received the drug «Intrafen» in injectable form, intravenously. Name of manufacturer of drug: GEN ILAC VE SAGLIK URUNLERI SANAYI VE TICARET, A.S. (Turkey). The main active substance of this drug is Ibuprofen 400mg/4ml for intravenous injection. Patients were injected intravenous ibuprofen at therapeutically effective doses for a minimal period of time. After receiving positive reactions to the drug at the initial stage of treatment, the dose and frequency of taking the drug was adjusted individually for each patient. Objective. This work is dedicated to evaluate the role of the intravenous Ibuprofen in the postoperative period in surgical practice. Material and methods. The study included 94 pediatric patients with esophagocoloplasty. Age of patients: from 10 months to 15 years (mean age 4.4 years), of which: 90 (96%) patients had post-burn stricture of the esophagus; 3 (3%) patients with esophageal atresia; 1 (1%) patient with a short esophagus. The number of female children - 51 (54.3%) patients, male - 43 (45.7%) patients. Results. The total number of patients receiving intravenous Ibuprofen in the postoperative period was 94. The optimal dose showed a good therapeutic effect. At the optimal dosage of 20 mg/kg/day, two patients experienced intra-abdominal bleeding. Follow-up time: 2 weeks after esophagocoloplasty. Conclusion. In patients with esophagocoloplasty, preventive intravenous administration of Ibuprofen showed a good therapeutic result. Patients noted a decrease in pain, which in turn led to a decrease in the need for emergency analgesia.
本文反映了非甾体类抗炎药在术后期的作用。研究对象为94例10个月~ 15岁(平均4.4岁)儿童手术资料。本中心所有食管结肠成形术患者术后均静脉注射“Intrafen”药物。药品制造商名称:GEN ILAC VE SAGLIK URUNLERI SANAYI VE TICARET, A.S.(土耳其)。本品主要活性物质为布洛芬400mg/4ml，静脉注射用。患者在最短的时间内静脉注射治疗有效剂量的布洛芬。在治疗初期对药物有积极反应后，对每位患者单独调整服药剂量和服药频率。目标。本研究旨在评价静脉注射布洛芬在手术术后的作用。材料和方法。该研究包括94例行食管结肠成形术的儿童患者。患者年龄:10个月~ 15岁(平均4.4岁)，其中:90例(96%)患者存在烧伤后食管狭窄;食管闭锁3例(3%);1例(1%)患者食管短。女童51例(54.3%)，男童43例(45.7%)。结果。术后接受静脉注射布洛芬的患者总数为94例。最佳剂量显示出良好的治疗效果。在最佳剂量为20mg /kg/天时，2例患者出现腹腔出血。随访时间:食管结肠成形术后2周。结论。在食管结肠成形术患者中，预防性静脉给予布洛芬显示出良好的治疗效果。患者注意到疼痛减轻，这反过来又导致对紧急镇痛的需求减少。
{"title":"THE USE OF INTRAVENOUS IBUPROFEN IN POSTOPERATIVE PERIOD","authors":"B. Shirtaev, N. Yerimova, M. Sundetov, K. Khalykov, D. Kurbanov, A. Akhbetova, S. Akilbekov, S. Mukashev, A. Kanazov, D. Bogdanova","doi":"10.35805/bsk2022i055","DOIUrl":"https://doi.org/10.35805/bsk2022i055","url":null,"abstract":"The article reflects the role of non-steroidal anti-inflammatory drugs in postoperative period. The study was conducted on the data of 94 operations of children aged from 10 months to 15 years (mean age 4.4 years). All patients of our center with esophagocoloplasty in the postoperative period received the drug «Intrafen» in injectable form, intravenously. Name of manufacturer of drug: GEN ILAC VE SAGLIK URUNLERI SANAYI VE TICARET, A.S. (Turkey). The main active substance of this drug is Ibuprofen 400mg/4ml for intravenous injection. Patients were injected intravenous ibuprofen at therapeutically effective doses for a minimal period of time. After receiving positive reactions to the drug at the initial stage of treatment, the dose and frequency of taking the drug was adjusted individually for each patient. Objective. This work is dedicated to evaluate the role of the intravenous Ibuprofen in the postoperative period in surgical practice. Material and methods. The study included 94 pediatric patients with esophagocoloplasty. Age of patients: from 10 months to 15 years (mean age 4.4 years), of which: 90 (96%) patients had post-burn stricture of the esophagus; 3 (3%) patients with esophageal atresia; 1 (1%) patient with a short esophagus. The number of female children - 51 (54.3%) patients, male - 43 (45.7%) patients. Results. The total number of patients receiving intravenous Ibuprofen in the postoperative period was 94. The optimal dose showed a good therapeutic effect. At the optimal dosage of 20 mg/kg/day, two patients experienced intra-abdominal bleeding. Follow-up time: 2 weeks after esophagocoloplasty. Conclusion. In patients with esophagocoloplasty, preventive intravenous administration of Ibuprofen showed a good therapeutic result. Patients noted a decrease in pain, which in turn led to a decrease in the need for emergency analgesia.","PeriodicalId":197118,"journal":{"name":"BULLETIN OF SURGERY IN KAZAKHSTAN","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130521456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：