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CATECHOL-O-METHYLTRANSFERASE (COMT) ENZYME LEVELS IN PATIENTS WITH PREOPERATIVE ANXIETY 术前焦虑患者的儿茶酚- o -甲基转移酶(comt)水平
Pub Date : 2022-01-10 DOI: 10.55047/comorbid.v1i1.37
Akhyar Hamongan Nasution, A. Lelo
The preoperative anxiety’s incidence is very high and mostly preoperative patients have anxiety. It was found that low COMT levels indicate a tendency to develop anxiety. Hence, this study aims to investigate COMT enzyme levels in patients with preoperative anxiety. This research is a purely experimental research with a pretest-posttest control group design and double-blind. Measurement of COMT enzyme levels was executed by utilizing ELISA technique. Blood samples were taken from preoperative anxiety patients who were assessed with the Amsterdam Preoperative Anxiety Information Scale (APAIS). The research was carried out at Haji Adam Malik General Hospital and Regional General Hospital dr. Pirngadi Medan, and Integrated Laboratory of the Faculty of Medicine, University of North Sumatra. The were 64 samples involved in this research that fit the inclusion and exclusion criteria. The findings show that COMT levels in the anxiety and control groups had differences with p values ​​= 0.014. In addition, COMT levels in the preoperative anxiety group were lower when compared to those without the preoperative anxiety group, where in the anxiety group had COMT enzyme levels of 0,14 ± 0,08 ng/dl, while in the control group had higher COMT levels 0,96 ± 1,11 ng/dl. The results showed that patients with preoperative anxiety had lower levels of the COMT enzyme compared to patients without preoperative anxiety. Researchers suspect there is a role for the COMT enzyme in causing preoperative anxiety.      
术前焦虑发生率很高,多数患者术前存在焦虑。研究发现,较低的COMT水平表明有产生焦虑的倾向。因此,本研究旨在探讨术前焦虑患者的COMT酶水平。本研究为纯实验研究,采用前测后测对照组设计,双盲。采用酶联免疫吸附法测定COMT酶水平。采用阿姆斯特丹术前焦虑信息量表(APAIS)评估术前焦虑患者的血样。这项研究是在哈吉亚当马利克综合医院和地区综合医院Pirngadi Medan博士以及北苏门答腊大学医学院综合实验室进行的。本研究共有64个样本符合纳入和排除标准。结果显示,焦虑组和对照组的COMT水平存在p值= 0.014的差异。此外,术前焦虑组的COMT水平低于术前无焦虑组,焦虑组的COMT酶水平为0.14±0.08 ng/dl,而对照组的COMT水平较高,为0.96±1.11 ng/dl。结果显示,术前焦虑患者的COMT酶水平较术前无焦虑患者低。研究人员怀疑COMT酶在引起术前焦虑中起着一定的作用。
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引用次数: 1
CLEAN AND HEALTHY LIVING BEHAVIOR IN THE FAMILY ENVIRONMENT AS A PREVENTION OF COVID-19 IN SERANG CITY 雪朗市家庭环境中清洁和健康的生活行为预防COVID-19
Pub Date : 2022-01-10 DOI: 10.55047/comorbid.v1i1.35
Stevany Afrizal, Inez Athallaisya Adinda
The rapid spread of the COVID-19 virus throughout the world has come as a complete shock, and it is causing serious concerns. The COVID-19 virus can be prevented with the help of a simple yet highly successful method called "clean and healthy living behavior" (PHBS). The health of family members is expected to improve as a result of the implementation of clean and healthy living behavior (PHBS) in the family environment, which includes adhering to health protocols, staying at home for those who do not have to leave the house, and allowing workers or employees to work from home (Work From Home/WFH). Family participation in PHBS is essential in order to prevent COVID-19 from spreading, as demonstrated by the emergence of COVID-19. The objective of this paper is to educate the community and families about PHBS, as well as to ensure that it is properly implemented. Descriptive qualitative interviews and scientific references are employed to perform the research. The researcher chose this title because he wants to break the chain of the COVID-19 virus's transmission in order to establish a family environment that is mindful of health and enhancing a healthy and clean family environment, so that people do not get sick as easily as before. A healthy family environment can increase productivity, so that family members will get used to implementing PHBS and children can grow up healthy and have adequate nutrition.      
新冠肺炎疫情在全球迅速蔓延,令人震惊,令人严重关切。COVID-19病毒可以通过一种简单但非常成功的方法来预防,这种方法被称为“清洁健康的生活行为”(PHBS)。由于在家庭环境中实施清洁和健康的生活行为(PHBS),预计家庭成员的健康将得到改善,其中包括遵守卫生协议,不需要离开家的人呆在家里,并允许工人或雇员在家工作(在家工作/WFH)。正如COVID-19的出现所证明的那样,家庭参与PHBS对于防止COVID-19传播至关重要。本文的目的是教育社区和家庭关于PHBS,以及确保它得到正确实施。采用描述性定性访谈和科学参考文献进行研究。之所以选择这个题目,是因为想要打破新冠病毒的传播链,建立注重健康的家庭环境,营造健康清洁的家庭环境,让人们不再像以前那样容易生病。健康的家庭环境可以提高生产力,使家庭成员习惯于实施PHBS,儿童可以健康成长并获得充足的营养。
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