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The effect of linear polarized near-infrared irradiation around the stellate ganglia on hormonal secretions 星状神经节周围线偏振近红外照射对激素分泌的影响
Pub Date : 2006-10-01 DOI: 10.1163/156856906778704614
H. Iwama, T. Komatsu, Masamichi Nishida, T. Sakamoto
AbstractLinear polarized near-infrared irradiation around the stellate ganglia (Lizer-SGB) is thought to have a similar effect to stellate ganglion block (SGB), namely, a reduced effect on stress. The effect of Lizer-SGB on various hormone levels was examined. Six adult male volunteers received bilateral Lizer-SGB, and blood was collected before and after this treatment, followed by measurements of plasma adrenocorticotropic hormone (ACTH) and serum cortisol (CS), luteinizing hormone (LH), testosterone (TS), thyroid stimulating hormone (TSH), triiodothyronine (T3) and thyroxine (T4). On a different day, the same measurements were taken from volunteers in the absence of irradiation. The results showed that ACTH, LH, TS and T4 levels were similar in treated and non-treated groups, whilst CS levels decreased after Lizer-SGB. Although TSH and T3 levels decreased, their values were not changed as a specific effect of Lizer-SGB. The results obtained showed that Lizer-SGB has an effect similar to SGB, regarding ...
【摘要】星状神经节(liser -SGB)周围的线偏振近红外辐射被认为具有与星状神经节阻滞(SGB)相似的作用,即对应力的影响降低。研究了Lizer-SGB对各种激素水平的影响。6名成年男性志愿者接受双侧Lizer-SGB治疗,分别于治疗前后采血,测定血浆促肾上腺皮质激素(ACTH)、血清皮质醇(CS)、促黄体生成素(LH)、睾酮(TS)、促甲状腺激素(TSH)、三碘甲状腺原氨酸(T3)、甲状腺素(T4)。在另一天,在没有辐射的情况下,对志愿者进行了相同的测量。结果显示,治疗组与非治疗组ACTH、LH、TS、T4水平基本一致,而CS水平在Lizer-SGB治疗后有所下降。虽然TSH和T3水平降低,但它们的值并没有作为Lizer-SGB的特异性作用而改变。结果表明,Lizer-SGB具有与SGB相似的效果,在…
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引用次数: 0
Histopathologic changes in liver induced by morphine and tramadol 吗啡和曲马多致肝脏组织病理学改变
Pub Date : 2006-10-01 DOI: 10.1163/156856906778704687
Z. Sevimli, H. Dursun, F. Erdoğan
Abstract Objective: Opioids are widely used for acute pain relief. We studied the postoperative effects of morphine and tramadol on the histopathology of liver in rabbits which had undergone isoflurane anesthesia. Methods: The study was carried out at the animal laboratories of the Medical Faculty, Ataturk University. The rabbits were divided into three treatment groups as control group (C), morphine group (M) and tramadol group (T) each composed of 10 rabbits. 3 ml 0.9% NaCl in the control group, 1 mg kg−1 in the morphine group, and 10 mg kg−1 in the tramadol group were administered twice a day for three days. At the end of the experimental period, the animals were sacrificed, and liver tissue samples were prepared for histopathologic assessment. Results: Hepatocyte degeneration, central vein dilatation, and mononuclear cell infiltration in the M group were more severe than those of the C group (p < 0.001). Hepatocyte degeneration, sinusoidal dilatation, central vein dilatation in the T group were more s...
摘要目的:阿片类药物广泛用于急性疼痛缓解。研究吗啡和曲马多对异氟醚麻醉家兔术后肝脏组织病理学的影响。方法:本研究在阿塔图尔克大学医学院动物实验室进行。将家兔分为对照组(C)、吗啡组(M)和曲马多组(T) 3个治疗组,每组10只。对照组0.9% NaCl 3 ml,吗啡组1 mg kg−1,曲马多组10 mg kg−1,每日2次,连用3 d。实验结束时,处死大鼠,取肝组织标本进行组织病理学检查。结果:M组肝细胞变性、中央静脉扩张、单核细胞浸润较C组严重(p < 0.001)。T组肝细胞变性、窦状静脉扩张、中央静脉扩张明显多于T组。
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引用次数: 11
Evaluation of peripheral nerve function using current perception threshold in the herpes zoster patients and the development of post-herpetic neuralgia 用电流感知阈值评价带状疱疹患者周围神经功能和带状疱疹后神经痛的发展
Pub Date : 2006-10-01 DOI: 10.1163/156856906778704623
K. Doi, H. Kushizaki, S. Sakura, T. Nikai, Yoji Saito
Abstract Background: We performed this study to evaluate peripheral nerve function in patients with herpes zoster (HZ) using current perception threshold (CPT) and to compare results between patients who developed post-herpetic neuralgia (PHN) and those who did not. Methods: With Institutional Review Board (IRB) approval and informed consent, 27 patients with HZ were enrolled in the study. At the first visit, all patients were examined clinically and neurophysiologically. CPTs were determined at stimulus frequencies of 2000, 250, and 5 Hz in the affected region and in the contralateral site. Patients were re-examined 6 months after the onset of their symptoms. Patients who still had pain were defined as PHN patients and the others as non-PHN patients. Results: CPT values in affected areas were significantly higher than those in unaffected areas. Thirteen patients were included in the PHN group, and 14 patients in the non-PHN group. Visual analogue scale (VAS) values at the first visit were significantly h...
摘要背景:本研究旨在利用电流感知阈值(CPT)评估带状疱疹(HZ)患者的周围神经功能,并比较发生带状疱疹后神经痛(PHN)和未发生带状疱疹后神经痛(PHN)患者的结果。方法:经机构审查委员会(IRB)批准和知情同意,27例HZ患者入组研究。首次就诊时,对所有患者进行临床和神经生理检查。在受影响区域和对侧部位分别以2000、250和5hz的刺激频率测定CPTs。患者在出现症状6个月后再次接受检查。仍有疼痛的患者被定义为PHN患者,其他患者被定义为非PHN患者。结果:疫区CPT值显著高于未疫区。PHN组13例,非PHN组14例。首次访视时的视觉模拟评分(VAS)值显著高于对照组。
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引用次数: 0
Non specific low back pain in a Turkish population based sample of school children: a field survey with analysis of associated factors 非特异性腰痛在土耳其人口为基础的学龄儿童样本:现场调查与分析相关因素
Pub Date : 2006-10-01 DOI: 10.1163/156856906778704678
U. Cavlak, A. Cimbiz, B. Akdağ
AbstractThe aim of this study was to evaluate the prevalence of low back pain (LBP) among school children and the consequences that this problem may have in relation to gender. This study was designed as a cross-sectional 22-question questionnaire-based on LBP completed by a 10- to 18-year-old Turkish sample. The subjects were 624 school children (335 boys and 289 girls) who were attending primary, secondary or high schools in Denizli, Turkey (mean age = 13.91 years, SD = 2.34). Each subject completed the questionnaire under supervision by an investigator during school time. Data were analysed comparing the two genders. Two hundred and ninety-two school children (46.7%) had LBP. Boys were 153 (52.4%) and girls 139 (47.6%). Both boys and girls with LBP reported that LBP did not interfere negatively with their school performance (67.5%) and with daily activities (87.5%). The risk factors should be investigated at early stages of the life. Therefore, a national LBP prevention program should be performed at c...
摘要本研究的目的是评估学童腰痛(LBP)的患病率,以及这一问题可能与性别有关的后果。本研究设计为一份基于LBP的22题横断面问卷,由10至18岁的土耳其样本完成。研究对象为624名在校儿童(335名男孩和289名女孩),他们在土耳其德尼兹利的小学、初中或高中就读(平均年龄= 13.91岁,SD = 2.34)。每位受试者在上学期间在一名调查员的监督下完成问卷。对两种性别的数据进行了比较分析。192名学童(46.7%)患有LBP。男生153例(52.4%),女生139例(47.6%)。患有LBP的男孩和女孩都报告说,LBP对他们的学习成绩(67.5%)和日常活动(87.5%)没有负面影响。风险因素应该在生命的早期阶段进行调查。因此,国家预防腰痛计划应在全国范围内实施。
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引用次数: 5
The effects of intra-operative low-dose dexmedetomidine infusion on postoperative pain in patients undergoing septorhinoplasty 术中低剂量右美托咪定对鼻中隔成形术患者术后疼痛的影响
Pub Date : 2006-10-01 DOI: 10.1179/016911106779499028
M. Cicek, A. Yücel, E. Gedik, O. Sagir, A. But, M. O. Ersoy
Abstract Study objective: To determine the effects of intra-operative low-dose dexmedetomidine infusion on postoperative morphine consumption, pain, sedation and patient satisfaction in patients undergoing septorhinoplasty. Method: Fifty adult patients were randomised to receive either dexmedetomidine (a loading dose of 1 μg kg−1 for the first ten minutes and a maintenance dose of 0.2 μg kg−1 h−1 afterwards, Group D) or 0.9% saline in the same manner (Group C) after induction of anaesthesia. At the end of the operation, the infusions were discontinued. After extubation, patient controlled analgesia was started intravenously. Results: Patients in Group D consumed 47% less morphine than patients in Group C during the first 24 h and had a lower cumulative morphine consumption at all times after starting patient controlled analgesia (7.08 mg vs. 8.56 mg at 2 h (p < 0.05), 10.84 mg vs. 14.0 mg at 4 h (p < 0.05), 13.56 mg vs. 18.28 mg at 6 h (p < 0.05) and 17.96 mg vs. 33.72 mg at 24 h (p < 0.05), respectively ...
摘要研究目的:探讨术中低剂量右美托咪定对鼻中隔成形术患者术后吗啡消耗、疼痛、镇静及患者满意度的影响。方法:50例成年患者随机分为两组,分别在麻醉诱导后给予右美托咪定(前10分钟负荷剂量为1 μg kg−1,后维持剂量为0.2 μg kg−1 h−1)或0.9%生理盐水(C组)。手术结束时,停止输注。拔管后,开始静脉给予患者自控镇痛。结果:患者在D组吗啡消耗47%低于C组患者在第一个24小时,累积吗啡低消费在任何时候开始后病人自控镇痛(7.08毫克和8.56毫克2 h (p < 0.05), 10.84毫克和14.0毫克,4 h (p < 0.05), 13.56毫克和18.28毫克6 h (p < 0.05)和17.96毫克和33.72毫克分别为24小时(p < 0.05),…
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引用次数: 10
Management of the stress fracture of the tibia using expandable intramedullary nail in a patient with osteoarthritis and osteomalacia 可膨胀髓内钉治疗骨关节炎和骨软化症患者胫骨应力性骨折1例
Pub Date : 2006-10-01 DOI: 10.1163/156856906778704696
A. Atalay, F. Inanici, B. Volkan, P. Kiratli, A. Öznur
AbstractStress fractures may occur either due to an extreme muscle strain (fatigue fracture) or a normal strain within the context of pre-existing bone weakness (insufficiency fracture). Stress fractures of the tibia associated with osteoarthritis of the knee have been described in the literature. In osteoarthritic patients with genu varum deformity altered biomechanics lead to further strain on bone. We describe a 68 year-old woman with genu varum deformity due to osteoarthritis of the knee and concomitant osteomalacia due to lack of exposure to sunlight. She was operated on using an expandable intramedullary nail which enabled early mobilization and prevented further complications such as nonunion and sequential fractures.
应力性骨折的发生可能是由于极度的肌肉劳损(疲劳骨折),也可能是在已有的骨无力(不全骨折)的情况下发生的正常劳损。胫骨应力性骨折伴膝骨关节炎已在文献中有所描述。在膝内翻畸形的骨关节炎患者中,生物力学的改变会导致进一步的骨张力。我们描述了一位68岁的女性,由于缺乏阳光照射,膝关节骨关节炎和伴随的骨软化症导致膝内翻畸形。她使用可扩展髓内钉进行手术,使其能够早期活动,并防止进一步的并发症,如骨不连和连续性骨折。
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引用次数: 0
Hydromorphone in elderly patients with polypathia and with severe pain 氢吗啡酮在老年多病伴剧烈疼痛患者中的应用
Pub Date : 2006-10-01 DOI: 10.1179/016911106779498993
J. Nadstawek, H. Wartenberg, M. Schenk, S. Wirz
AbstractThere continue to exist serious deficiencies in the analgesic therapy of elderly patients and patients with polypathia and severe pain. Orally administered controlled-release hydromorphone (see Note 1) appears to be particularly suitable for this patient group due to its pharmacological and metabolic benefits. The aim of the present prospective, multicentre study was to analyse the effects of hydromorphone therapy on quality of analgesia and potential side effects. Patients and methods. 567 elderly patients with severe, predominantly tumour-related or musculoskeletal pain were included in this study. The majority of these patients had received prior analgesic therapy. The following parameters were measured before initiating treatment with orally administered controlled-release hydromorphone and at three further assessments during the therapy: the daily dose required, intensity of pain (measured on the Numeric Rating Scale: 0 = no pain to 10 = worst pain imaginable); typical opioid-related side eff...
摘要老年患者及多病重症患者的镇痛治疗仍存在严重不足。口服控释氢吗啡酮(见注1)由于其药理和代谢益处,似乎特别适合该患者组。本前瞻性多中心研究的目的是分析氢吗啡酮治疗对镇痛质量和潜在副作用的影响。患者和方法。567例主要为肿瘤相关疼痛或肌肉骨骼疼痛的老年患者纳入本研究。这些患者中的大多数先前接受过镇痛治疗。在口服控释氢吗啡酮开始治疗前和治疗期间的三个进一步评估中测量以下参数:每日所需剂量,疼痛强度(在数字评定量表上测量:0 =无疼痛至10 =可想象的最严重疼痛);典型的阿片类药物副作用……
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引用次数: 3
The analysis of tissue coring of epithelial cells in spinal block performed with 25-gauge Pencil-point and Ballpen ® spinal needles 用25号Pencil-point和Ballpen®脊髓针分析脊髓阻滞上皮细胞的组织芯化
Pub Date : 2006-10-01 DOI: 10.1179/016911106779498975
Gürayten Özyurt, E. Basagan-Mogol, Ş. Tolunay, N. Kelebek-Girgin
AbstractDuring lumbar puncture for spinal anaesthesia, the needle may carry tissue cores into the subarachnoid space, with the potential complication of intraspinal lumbar epidermoid tumour. Coring is believed to occur not only with hollow needles, but even with newer styletted spinal ones. This prospective randomised, blinded study was undertaken to analyse the tissue coring of epithelial cells with the new Ballpen® spinal needles, and the more widely used Pencil-point spinal needles. Forty patients undergoing spinal anaesthesia for transurethral prostate resection were randomized into two groups according to the spinal needle type. Spinal anaesthesia was performed with Pencil-point 25-gauge and Ballpen® 25-gauge spinal needles with the aid of 20-gauge introducer needle. After removal of the stylette, 1 ml of cerebrospinal fluid was collected by free-flow into a sterile test tube, and investigated under the light microscope by a pathologist blinded to the type of needle. Any sample containing at least on...
【摘要】在腰椎穿刺进行脊髓麻醉时,针头可能携带组织核进入蛛网膜下腔,有腰椎棘内表皮样瘤的潜在并发症。据信,不仅空心针会取芯,甚至新式的脊椎针也会取芯。本前瞻性随机盲法研究采用新型Ballpen®脊髓针和更广泛使用的Pencil-point脊髓针分析上皮细胞的组织芯化。选择40例经尿道前列腺切除脊髓麻醉患者,根据脊髓针类型随机分为两组。脊髓麻醉采用Pencil-point 25-gauge和Ballpen®25-gauge脊髓针,并辅以20-gauge引入针。取出针柱后,取1 ml脑脊液自由流动至无菌试管中,由盲针病理学家在光镜下观察。任何样品至少含有…
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引用次数: 0
Esmolol reduces pain on injection of propofol 艾司洛尔减轻注射异丙酚时的疼痛
Pub Date : 2006-10-01 DOI: 10.1163/156856906778704704
F. N. Kaya, B. Yavaşçaoğlu, E. Moğol, R. İşçimen, Berrin Özcan
Abstract Background and objective: This randomized, double-blind, placebo-controlled study was carried out to determine the effect of esmolol on the incidence and severity of pain during propofol injection using a venous retention technique, and to compare it with lidocaine and placebo. Methods: After institutional ethical approval, 150 ASA I-II patients (ages 21–70) undergoing general anaesthesia for elective surgery were randomized to receive esmolol (0.5 mg/kg) (n = 50), lidocaine (0.5 mg/kg) (n = 50) or saline (placebo group, n = 50) diluted into a 5 ml solution after tourniquet application (70 mmHg) on the forearm. The occlusion was released after 30 seconds and 25% of the calculated induction dose of propofol was administrated at the rate of 0.5 ml/s. The patients were observed and asked immediately if they had pain in the arm, and the response was recorded. Results: Twenty-seven patients in the esmolol group, 28 in the lidocaine group, and 8 in the placebo group reported no pain (both groups vs. pl...
背景与目的:本研究采用随机、双盲、安慰剂对照的方法,探讨静脉留置技术下艾司洛尔对异丙酚注射过程中疼痛发生率和严重程度的影响,并与利多卡因和安慰剂进行比较。方法:经机构伦理批准,150例ASA I-II期择期手术全麻患者(年龄21-70岁)随机分为艾斯洛尔(0.5 mg/kg) (n = 50)、利多卡因(0.5 mg/kg) (n = 50)或生理盐水(安慰剂组,n = 50),在前臂止血带(70 mmHg)应用后稀释成5 ml溶液。30秒后解除闭塞,以0.5 ml/s的速率给予计算诱导剂量的25%异丙酚。观察患者,并立即询问他们的手臂是否疼痛,并记录他们的反应。结果:艾司洛尔组27例,利多卡因组28例,安慰剂组8例无疼痛(两组均无疼痛)。
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引用次数: 1
Incidental paravertebral hydatid cyst presenting with neck pain 偶发性椎旁棘球蚴病,表现为颈部疼痛
Pub Date : 2006-10-01 DOI: 10.1179/016911106779499046
B. Atalay, C. Yılmaz, N. Çetinalp, N. Altinors
AbstractHydatidosis is a disease usually found in rural and agricultural communities. Disease may affect any tissue, but hydatid disease of the liver and lung is quite common. Spinal hydatidosis is an uncommon manifestation of the parasite Echinococcus affecting fewer than 1% of patients with hydatid disease. A 45-year-old woman was admitted to our hospital with neck pain and a palpable mass over her lower neck. Magnetic resonance imaging of the cervical region revealed a cystic mass lesion embedded in the left paraspinal muscles. The patient was operated and the lesion was totally excised. Histopathological examination revealed a hydatid cyst. Complete systematic and radiological examination was made to detect any hydatid cyst in the other organs, but no other cysts were found. She received oral albendazole therapy (800 mg daily) for three, 3-week protocols. Control systemic and radiological examinations including the cervical MRI six months after treatment revealed normal findings without any cyst forma...
摘要草皮病是一种常见于农村和农业社区的疾病。疾病可影响任何组织,但肝和肺的包虫病是相当常见的。棘球蚴病是一种罕见的寄生虫棘球蚴病的表现,影响不到1%的棘球蚴病患者。一名45岁女性因颈部疼痛和下颈部可触及的肿块入住我院。颈椎核磁共振显示左侧棘旁肌囊性肿块。病人接受手术,病灶被完全切除。组织病理学检查显示为包虫囊肿。我们做了完整的系统和放射学检查,在其他器官中发现任何包虫囊肿,但没有发现其他囊肿。她接受口服阿苯达唑治疗(每天800毫克),为期3周。治疗6个月后,全身检查和放射学检查(包括颈椎MRI)显示正常,没有任何囊肿形成。
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引用次数: 2
期刊
Pain Clinic
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