Sumedh Joshi, M. Megha, B. Bhide, S. Ghildiyal, T. Nesari
{"title":"Physico-chemical and Phytochemical Analysis of Sphaeranthus indicus Linn. (Whole Plant)","authors":"Sumedh Joshi, M. Megha, B. Bhide, S. Ghildiyal, T. Nesari","doi":"10.5530/pres.15.3.051","DOIUrl":"https://doi.org/10.5530/pres.15.3.051","url":null,"abstract":"","PeriodicalId":19813,"journal":{"name":"Pharmacognosy Research","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48003464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cinthia dos S. Alves, H. Frias, L. Bonamin, E. Bondan, C. Coelho, M. Martins, M. Bernardi, I. Suffredini
{"title":"Luffa operculata (L.) Cogn. Gestational Exposition Induces Anxiety-like Behavior and Interferes with Melatonin and Inflammation in Young Female Rats","authors":"Cinthia dos S. Alves, H. Frias, L. Bonamin, E. Bondan, C. Coelho, M. Martins, M. Bernardi, I. Suffredini","doi":"10.5530/pres.15.3.055","DOIUrl":"https://doi.org/10.5530/pres.15.3.055","url":null,"abstract":"","PeriodicalId":19813,"journal":{"name":"Pharmacognosy Research","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42956230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Kadam, Damini Kallyanrao Giram, Sameer Khamroddin Shaikh, K. Yadav, A. Karanje, M. Patil
{"title":"Pharmacognostic, Chemical Characterization Studies on Oyster Mushroom (Pleurotus ostreatus)","authors":"P. Kadam, Damini Kallyanrao Giram, Sameer Khamroddin Shaikh, K. Yadav, A. Karanje, M. Patil","doi":"10.5530/pres.15.3.054","DOIUrl":"https://doi.org/10.5530/pres.15.3.054","url":null,"abstract":"","PeriodicalId":19813,"journal":{"name":"Pharmacognosy Research","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48927951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Rather, Hamiduddin Hamiduddin, M. Ikram, Md. Naquibuddin
{"title":"Formulation and in vitro Evaluation of Tablet Dosage form of Unani Anti-diabetic Powder Containing Gymnema sylvestre R. Br, Syzygium cuminii Linn. and Zingiber officinale Rosc.","authors":"G. Rather, Hamiduddin Hamiduddin, M. Ikram, Md. Naquibuddin","doi":"10.5530/pres.15.3.060","DOIUrl":"https://doi.org/10.5530/pres.15.3.060","url":null,"abstract":"","PeriodicalId":19813,"journal":{"name":"Pharmacognosy Research","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47044465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Carneiro, G. Pinheiro, A. Baseggio, M. R. Marostica-Junior, A. Sawaya
{"title":"Chemical Composition and Antioxidant Activity of Essential Oil from Male and Female Schinus terebinthifolius","authors":"M. Carneiro, G. Pinheiro, A. Baseggio, M. R. Marostica-Junior, A. Sawaya","doi":"10.5530/pres.15.3.050","DOIUrl":"https://doi.org/10.5530/pres.15.3.050","url":null,"abstract":"","PeriodicalId":19813,"journal":{"name":"Pharmacognosy Research","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45435447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. P, Divya Kg, Udhayavani C, Murugammal S, S. R, Sunil Kumar KN
{"title":"Morpho-anatomy and HPTLC Profiling of Senna Mill. Seeds Used in Traditional System of Indian Medicine","authors":"R. P, Divya Kg, Udhayavani C, Murugammal S, S. R, Sunil Kumar KN","doi":"10.5530/pres.15.3.058","DOIUrl":"https://doi.org/10.5530/pres.15.3.058","url":null,"abstract":"","PeriodicalId":19813,"journal":{"name":"Pharmacognosy Research","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44837641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Mondal, K. Bhar, P. Mondal, N. Panigrahi, S. Sahoo, Pydi Swetha, S. Chakraborty, Nooka Yaswanth Teja, N. Parveen
{"title":"In Quest of the Mysterious Holistic Vedic Herb Bacopa monnieri (L.) Pennell","authors":"S. Mondal, K. Bhar, P. Mondal, N. Panigrahi, S. Sahoo, Pydi Swetha, S. Chakraborty, Nooka Yaswanth Teja, N. Parveen","doi":"10.5530/pres.15.3.045","DOIUrl":"https://doi.org/10.5530/pres.15.3.045","url":null,"abstract":"","PeriodicalId":19813,"journal":{"name":"Pharmacognosy Research","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44864008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sonam Pushkar, V. Varshney, Pushpendra Pushkar, H. Sagar
Tuberculosis (TB) is a leading infectious disease that caused the deaths of a total of 1.5 million people in 2020 and is one of the top causes of death globally. India is a country with the highest TB burden, and it may affect all age groups. It is caused by the Mycobacterium tuberculosis bacteria, an intracellular pathogen, and its multidrug and extensively drug-resistant strains, which continue to emerge and spread, resulting in the deadliest infectious disease. After a gap of more than 40 years, the FDA approvals over the past decade of three second-line anti-TB drugs, bedaquiline, delamanid, and pretomanid, have been major forward steps in the management of drug-resistant-TB (DR-TB). Many medicinal plants such as Zanthoxylum leprieurii, Lantana camara , and Cryptolepis sanguinolenta have extensive therapeutic potential and represent a prospective option to fight against DR-TB. Some novel compounds are in the early clinical trial phases such as DprE1 inhibitors TBA-7371 and BTZ-043, and many others that are showing promising futures. This review describes DR-TB and its current chemotherapy guidelines including novel and repurposed drugs that are included in the anti-TB regimens, medicinal plants that have therapeutic potential for the development of drug-hit candidates, drugs that are currently in clinical development, host-directed therapy, and new drug delivery systems to better understand the novel therapeutic approaches that are currently being studied for the efficacious and safe management of DR-TB, a worldwide health problem.
{"title":"Novel Approaches for the Treatment of Drug-Resistant Tuberculosis","authors":"Sonam Pushkar, V. Varshney, Pushpendra Pushkar, H. Sagar","doi":"10.5530/pres.15.2.025","DOIUrl":"https://doi.org/10.5530/pres.15.2.025","url":null,"abstract":"Tuberculosis (TB) is a leading infectious disease that caused the deaths of a total of 1.5 million people in 2020 and is one of the top causes of death globally. India is a country with the highest TB burden, and it may affect all age groups. It is caused by the Mycobacterium tuberculosis bacteria, an intracellular pathogen, and its multidrug and extensively drug-resistant strains, which continue to emerge and spread, resulting in the deadliest infectious disease. After a gap of more than 40 years, the FDA approvals over the past decade of three second-line anti-TB drugs, bedaquiline, delamanid, and pretomanid, have been major forward steps in the management of drug-resistant-TB (DR-TB). Many medicinal plants such as Zanthoxylum leprieurii, Lantana camara , and Cryptolepis sanguinolenta have extensive therapeutic potential and represent a prospective option to fight against DR-TB. Some novel compounds are in the early clinical trial phases such as DprE1 inhibitors TBA-7371 and BTZ-043, and many others that are showing promising futures. This review describes DR-TB and its current chemotherapy guidelines including novel and repurposed drugs that are included in the anti-TB regimens, medicinal plants that have therapeutic potential for the development of drug-hit candidates, drugs that are currently in clinical development, host-directed therapy, and new drug delivery systems to better understand the novel therapeutic approaches that are currently being studied for the efficacious and safe management of DR-TB, a worldwide health problem.","PeriodicalId":19813,"journal":{"name":"Pharmacognosy Research","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45428632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Boudiba, Selcuk Kucukaydin, A. N. Tamfu, Kom Blaise, Aristide Munvera, Y. Arab, O. Ceylan, R. Dinică
{"title":"HPLC-DAD Phenolic Composition, Antioxidant, Anticholinesterase, Antidiabetic and Anti-quorum Sensing Properties of Bitter Kola (Garcinia kola) and Kolanut (Cola acuminata)","authors":"S. Boudiba, Selcuk Kucukaydin, A. N. Tamfu, Kom Blaise, Aristide Munvera, Y. Arab, O. Ceylan, R. Dinică","doi":"10.5530/pres.15.2.040","DOIUrl":"https://doi.org/10.5530/pres.15.2.040","url":null,"abstract":"","PeriodicalId":19813,"journal":{"name":"Pharmacognosy Research","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46581119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Guntupalli, N. Malothu, A. Areti, B. N. Nalluri, Praveen Sivadasu, N. Alla
Introduction: In the phytochemical analysis of various multi component mixtures, Capillary electrophoresis (CE) method was considered as the best alternative tool due to high efficiency resolution separations, low solvent consumption and less maintenance costs. Materials and Methods: This study uses CE and high-performance liquid chromatography (HPLC) methods to evaluate the major components of methanolic leaf extract of Rutaceous plants. And also, to assess the purity of the components in isolated fractions and most importantly for the qualitative identification of the individual components of extracts based upon the relative retention time and UV profile. Results: The separation of the compounds in HPLC was attained by using ACE-5-C 18 (250 x 4.6 mm) with a flow rate of 1.5 ml/min, with the UV detection at 254 nm and CE was equipped with a UV diode-array detector and bare, fused silica capillaries (56 cm 50 μm) with micro extended light path were used for the separations. Conclusion: Our study reveals that CE technique is a simple, economical and convenient method and shown high-resolution for multi-components found in plant extracts compared with HPLC profiles.
{"title":"Separation of Methanolic Leaf Extracts of Three Rutaceous Plants by Capillary Electrophoresis and High-Performance Liquid Chromatography Methods","authors":"C. Guntupalli, N. Malothu, A. Areti, B. N. Nalluri, Praveen Sivadasu, N. Alla","doi":"10.5530/pres.15.2.042","DOIUrl":"https://doi.org/10.5530/pres.15.2.042","url":null,"abstract":"Introduction: In the phytochemical analysis of various multi component mixtures, Capillary electrophoresis (CE) method was considered as the best alternative tool due to high efficiency resolution separations, low solvent consumption and less maintenance costs. Materials and Methods: This study uses CE and high-performance liquid chromatography (HPLC) methods to evaluate the major components of methanolic leaf extract of Rutaceous plants. And also, to assess the purity of the components in isolated fractions and most importantly for the qualitative identification of the individual components of extracts based upon the relative retention time and UV profile. Results: The separation of the compounds in HPLC was attained by using ACE-5-C 18 (250 x 4.6 mm) with a flow rate of 1.5 ml/min, with the UV detection at 254 nm and CE was equipped with a UV diode-array detector and bare, fused silica capillaries (56 cm 50 μm) with micro extended light path were used for the separations. Conclusion: Our study reveals that CE technique is a simple, economical and convenient method and shown high-resolution for multi-components found in plant extracts compared with HPLC profiles.","PeriodicalId":19813,"journal":{"name":"Pharmacognosy Research","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47346244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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