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Outcomes of general paediatric surgical neonates managed at the Nelson Mandela Children's Hospital, Johannesburg, South Africa. 南非约翰内斯堡纳尔逊·曼德拉儿童医院普通儿科手术新生儿的结局
IF 1.6 3区 医学 Q2 PEDIATRICS Pub Date : 2026-02-27 DOI: 10.1007/s00383-026-06365-y
Sphamandla Zulu, Karen Milford, Andrew Grieve

Background: Early identification of high-risk surgical neonates is essential in resource-limited settings. Risk stratification tools such as the Score for Neonatal Acute Physiology with Perinatal Extension II (SNAPPE II) are widely used in neonatal intensive care units but have not been validated in surgical neonatal populations in sub-Saharan Africa. This study evaluated outcomes and the prognostic utility of SNAPPE II in surgical neonates.

Methods: A 5-year retrospective cohort study was conducted including neonates admitted under general paediatric surgery to the neonatal intensive care unit at Nelson Mandela Children's Hospital. SNAPPE II scores were calculated within 12 h of admission. Associations between SNAPPE II and mortality were assessed using relative risk, odds ratios, and receiver operating characteristic (ROC) analysis.

Results: 380 neonates were analysed. Overall mortality was 22.6%, with sepsis accounting for 65.1% deaths. SNAPPE II demonstrated strong prognostic performance: scores > 20 were associated with markedly increased mortality (relative risk 9.2, odds ratio 43.7), and no neonates survived with scores ≥ 40. ROC analysis showed excellent discrimination (AUC 0.88), with an optimal cut-off of 25.

Conclusion: SNAPPE II reliably predicts mortality in surgical neonates and supports early triage, rational resource allocation, and informed family counselling in resource-limited neonatal surgical units.

背景:在资源有限的情况下,早期识别高危外科新生儿是至关重要的。风险分层工具,如围产期延长期新生儿急性生理评分(SNAPPE II),广泛用于新生儿重症监护病房,但尚未在撒哈拉以南非洲的外科新生儿人群中得到验证。本研究评估了SNAPPE II在外科新生儿中的疗效和预后效用。方法:对纳尔逊·曼德拉儿童医院新生儿重症监护病房接受普通儿科手术的新生儿进行了为期5年的回顾性队列研究。入院后12小时内计算SNAPPE II评分。使用相对风险、优势比和受试者工作特征(ROC)分析评估SNAPPE II与死亡率之间的关联。结果:对380例新生儿进行了分析。总死亡率为22.6%,败血症占65.1%。SNAPPE II表现出强大的预后表现:评分bbb20与死亡率显著增加相关(相对风险9.2,优势比43.7),评分≥40的新生儿没有存活。ROC分析显示极好的判别(AUC 0.88),最佳截止值为25。结论:SNAPPE II可靠地预测手术新生儿死亡率,并支持资源有限的新生儿外科病房的早期分诊、合理资源分配和知情的家庭咨询。
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引用次数: 0
Advancing pilonidal disease care through pediatric endoscopic treatment (PEPSiT): early insights. 通过儿童内窥镜治疗(PEPSiT)推进毛毛膜疾病护理:早期见解。
IF 1.6 3区 医学 Q2 PEDIATRICS Pub Date : 2026-02-27 DOI: 10.1007/s00383-026-06361-2
Maziar Fazel Darbandi, Mackenzie Hoy, Giuseppe Retrosi

Background: Pilonidal Sinus Disease (PSD) is an acquired inflammatory condition with no standard treatment. We evaluated our initial experience with Pediatric Endoscopic Pilonidal Sinus Treatment (PEPSiT).

Methods: We retrospectively reviewed all PEPSiT cases from May 2021-January 2025. Data collected included demographics, presentation, comorbidities, BMI, surgical time, anesthesia, hospital stay, complications, healing, recurrence, and follow-up (median, range).

Results: Thirty-two patients (18 males) underwent PEPSiT, median age 15 years (11-18), BMI 26.6 kg/m² (16.7-51.6). None had prior surgery for PSD. Three had comorbidities (two with type 1 diabetes, one with Hemophilia B). Median operative time was 39 min (19-58). All were day surgery procedures; 28 under sedation/local and 4 under general anesthesia. Median healing was 3 months (1-24). Complications included one granuloma (treated with silver nitrate) and one hematoma. All resumed normal activities the next day. Median follow-up was 9 months (1-52). Three recurrences were successfully treated with redo-PEPSiT.

Conclusion: Our outcomes suggest that PEPSiT is a safe, effective option for PSD. However, larger prospective studies are needed.

背景:毛窦病(PSD)是一种获得性炎症,没有标准的治疗方法。我们评估了小儿内窥镜治疗脊髓毛窦(PEPSiT)的初步经验。方法:回顾性分析2021年5月至2025年1月期间所有PEPSiT病例。收集的数据包括人口统计学、表现、合并症、BMI、手术时间、麻醉、住院时间、并发症、愈合、复发和随访(中位数,范围)。结果:32例患者(男性18例)接受PEPSiT治疗,中位年龄15岁(11-18岁),BMI 26.6 kg/m²(16.7-51.6)。没有人之前因PSD做过手术。其中3人有合并症(2人患有1型糖尿病,1人患有B型血友病)。中位手术时间39 min(19-58)。所有手术均为日间手术;镇静/局部麻醉28例,全身麻醉4例。中位愈合时间为3个月(1-24)。并发症包括一例肉芽肿(用硝酸银治疗)和一例血肿。第二天,所有人都恢复了正常活动。中位随访时间为9个月(1-52)。3例复发均成功地接受了redo-PEPSiT治疗。结论:我们的结果表明PEPSiT是治疗PSD的一种安全、有效的选择。然而,还需要更大规模的前瞻性研究。
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引用次数: 0
Operative and non-operative management of acute appendicitis in children: a narrative review. 儿童急性阑尾炎的手术与非手术治疗:综述。
IF 1.6 3区 医学 Q2 PEDIATRICS Pub Date : 2026-02-26 DOI: 10.1007/s00383-026-06358-x
Bo Hong, Kai Zhao, Geng Zhu
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引用次数: 0
Recto-sacral index for diagnosis of rectal dilatation in male intermediate/high-type anorectal malformations: a retrospective cohort study. 直肠-骶指数对男性中/高型肛肠畸形直肠扩张诊断的回顾性队列研究。
IF 1.6 3区 医学 Q2 PEDIATRICS Pub Date : 2026-02-26 DOI: 10.1007/s00383-026-06326-5
Siqi Li, Hang Xu, Meng Wang, Long Li

Purpose: Rectal dilatation is common in anorectal malformations (ARMs), predisposing patients to postoperative defecation dysfunction. However, studies of diagnostic criteria and risk factors are lacking.

Methods: This retrospective study enrolled 100 male patients with intermediate/high-type ARMs who underwent high-pressure distal colostogram (HPC) prior to anoplasty. The recto-sacral index (RSI), defined as the maximum diameter of the rectal pouch divided by the height of the second sacral vertebra, was developed and measured. Patients were categorized based on intraoperative and pathological findings of rectal dilatation. Demographic and fistula-related factors were compared between groups. Receiver operating characteristic (ROC) curve analysis was used to determine the optimal RSI cutoff for diagnosing rectal dilatation.

Results: The incidence of rectal dilatation and the recto-sacral index (RSI) varied significantly according to ARMs type (P = 0.001 and P < 0.001, respectively), being highest in rectovesical and rectoprostatic (high-type) fistulas. A higher RSI was also associated with the absence of meconium per urethra (P = 0.029) and longer fistula length (P = 0.039). The RSI was significantly larger in the dilatation group (2.54 ± 0.09) than in the non-dilatation group (1.89 ± 0.05, P < 0.001). ROC analysis identified an RSI cutoff of > 2.34 for diagnosing rectal dilatation, with an area under the curve of 0.841 (95% CI: 0.762-0.921, P < 0.001).

Conclusion: Rectovesical/prostatic fistulas, longer fistula, and no history of meconium per urethra may be predictive risk factors for rectal dilatation in male patients with ARMs. The RSI > 2.34 serves as a reliable and objective imaging-based criterion for preoperative identification of rectal dilatation.

目的:直肠扩张在肛肠畸形(ARMs)中很常见,易导致患者术后排便功能障碍。然而,缺乏对诊断标准和危险因素的研究。方法:本回顾性研究纳入了100例中/高型ARMs男性患者,他们在肛门成形术前接受了高压远端结肠造影(HPC)。直肠骶指数(RSI),定义为直肠囊的最大直径除以第二骶椎的高度,被开发和测量。根据术中及直肠扩张的病理表现对患者进行分类。比较两组间人口统计学及瘘管相关因素。采用受试者工作特征(ROC)曲线分析确定诊断直肠扩张的最佳RSI截止值。结果:不同ARMs类型直肠扩张发生率和直肠骶指数(RSI)差异有统计学意义(P = 0.001, P = 2.34),曲线下面积为0.841 (95% CI: 0.762 ~ 0.921, P)。结论:直肠/前列腺瘘、较长瘘管、无经尿道粪尿史可能是男性ARMs患者直肠扩张的预测危险因素。RSI >.2.34可作为直肠扩张术前客观可靠的影像学诊断标准。
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引用次数: 0
From vision to validation: operational pathways for safe, equitable AI in pediatric surgery. 从愿景到验证:安全、公平的人工智能在儿科手术中的操作途径。
IF 1.6 3区 医学 Q2 PEDIATRICS Pub Date : 2026-02-25 DOI: 10.1007/s00383-026-06339-0
M Vijayasimha
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引用次数: 0
Breastfeeding mitigates long-term infectious disease outcomes in individuals with a history of surgical disease as a neonate: a case-control cohort study. 母乳喂养减轻新生儿手术病史个体的长期传染病结局:一项病例对照队列研究。
IF 1.6 3区 医学 Q2 PEDIATRICS Pub Date : 2026-02-25 DOI: 10.1007/s00383-026-06319-4
Sakika Shimizu, Ghazale Farjam, Go Miyano, Suyin A Lum Min, Richard Keijzer
{"title":"Breastfeeding mitigates long-term infectious disease outcomes in individuals with a history of surgical disease as a neonate: a case-control cohort study.","authors":"Sakika Shimizu, Ghazale Farjam, Go Miyano, Suyin A Lum Min, Richard Keijzer","doi":"10.1007/s00383-026-06319-4","DOIUrl":"https://doi.org/10.1007/s00383-026-06319-4","url":null,"abstract":"","PeriodicalId":19832,"journal":{"name":"Pediatric Surgery International","volume":"42 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147284787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transgenic mouse model of congenital choledochal cyst. 先天性胆总管囊肿转基因小鼠模型。
IF 1.6 3区 医学 Q2 PEDIATRICS Pub Date : 2026-02-25 DOI: 10.1007/s00383-026-06360-3
Hannah Nicole Rinehardt, Alexis Martyn, Alexander Kolodychak, Masahiro Takeda, Madison Thomas, Lydia Liszewski, Abigail Rutkowski, Alexander Kreger, George Kingsley Gittes
{"title":"Transgenic mouse model of congenital choledochal cyst.","authors":"Hannah Nicole Rinehardt, Alexis Martyn, Alexander Kolodychak, Masahiro Takeda, Madison Thomas, Lydia Liszewski, Abigail Rutkowski, Alexander Kreger, George Kingsley Gittes","doi":"10.1007/s00383-026-06360-3","DOIUrl":"10.1007/s00383-026-06360-3","url":null,"abstract":"","PeriodicalId":19832,"journal":{"name":"Pediatric Surgery International","volume":"42 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147284737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction: Native liver survivors of portoenterostomy for biliary atresia with excellent outcome: redefining "successful" portoenterostomy. 更正:胆道闭锁的肝门肠造口术的本地肝脏幸存者有良好的结果:重新定义“成功”的门肠造口术。
IF 1.6 3区 医学 Q2 PEDIATRICS Pub Date : 2026-02-24 DOI: 10.1007/s00383-026-06321-w
Koichi Tsuboi, Hiroko Watayo, Takafumi Tsukui, Kazuto Suda, Eri Abe, Takashi Fujimoto, Takanori Ochi, Geoffrey J Lane, Hiroyuki Koga, Atsuyuki Yamataka
{"title":"Correction: Native liver survivors of portoenterostomy for biliary atresia with excellent outcome: redefining \"successful\" portoenterostomy.","authors":"Koichi Tsuboi, Hiroko Watayo, Takafumi Tsukui, Kazuto Suda, Eri Abe, Takashi Fujimoto, Takanori Ochi, Geoffrey J Lane, Hiroyuki Koga, Atsuyuki Yamataka","doi":"10.1007/s00383-026-06321-w","DOIUrl":"https://doi.org/10.1007/s00383-026-06321-w","url":null,"abstract":"","PeriodicalId":19832,"journal":{"name":"Pediatric Surgery International","volume":"42 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147284731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction: Laparoscopy for non-palpable undescended testis: comparing outcomes in syndromic and non-syndromic children. 纠正:腹腔镜治疗不可触及的隐睾:比较综合征和非综合征儿童的结果。
IF 1.6 3区 医学 Q2 PEDIATRICS Pub Date : 2026-02-24 DOI: 10.1007/s00383-026-06371-0
Agnes Raaschou Byström, Nilla Hallabro, Caroline Selin, Magnus Anderberg, Anna Börjesson, Martin Salö
{"title":"Correction: Laparoscopy for non-palpable undescended testis: comparing outcomes in syndromic and non-syndromic children.","authors":"Agnes Raaschou Byström, Nilla Hallabro, Caroline Selin, Magnus Anderberg, Anna Börjesson, Martin Salö","doi":"10.1007/s00383-026-06371-0","DOIUrl":"10.1007/s00383-026-06371-0","url":null,"abstract":"","PeriodicalId":19832,"journal":{"name":"Pediatric Surgery International","volume":"42 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12932342/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147284766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Small skin incision and less suture material reduce granuloma after laparoscopic gastrostomy: a prospective observational study in children. 儿童腹腔镜胃造口术后皮肤切口小、缝合材料少可减少肉芽肿:一项前瞻性观察研究。
IF 1.6 3区 医学 Q2 PEDIATRICS Pub Date : 2026-02-23 DOI: 10.1007/s00383-026-06347-0
Therese Hössjer, Niclas Högberg, Johan Danielson
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引用次数: 0
期刊
Pediatric Surgery International
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