{"title":"[FRET (Fluorescence Resonance Energy Transfer) for the determination of minimal inhibitory concentration of antibiotics].","authors":"Ulrike Holzgrabe","doi":"10.1002/pauz.201290004","DOIUrl":"https://doi.org/10.1002/pauz.201290004","url":null,"abstract":"","PeriodicalId":19878,"journal":{"name":"Pharmazie in Unserer Zeit","volume":"41 1","pages":"6-7"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/pauz.201290004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30549250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Experimental vaccination against tuberculosis].","authors":"Thomas Winckler","doi":"10.1002/pauz.201290006","DOIUrl":"https://doi.org/10.1002/pauz.201290006","url":null,"abstract":"","PeriodicalId":19878,"journal":{"name":"Pharmazie in Unserer Zeit","volume":"41 1","pages":"7-8"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/pauz.201290006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30549252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Editorial: Pharmazie in unserer Zeit 1/2012].","authors":"Peter Imming, Martin Schlitzer, Ulrike Holzgrabe","doi":"10.1002/pauz.201290002","DOIUrl":"https://doi.org/10.1002/pauz.201290002","url":null,"abstract":"","PeriodicalId":19878,"journal":{"name":"Pharmazie in Unserer Zeit","volume":" ","pages":"3"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/pauz.201290002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39967297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mikrobiologie. Die Entdeckung der unsichtbaren Welt. Von Gerhart Drews","authors":"I. Zündorf","doi":"10.1002/PAUZ.201290018","DOIUrl":"https://doi.org/10.1002/PAUZ.201290018","url":null,"abstract":"","PeriodicalId":19878,"journal":{"name":"Pharmazie in Unserer Zeit","volume":"112 1","pages":"94-95"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79419092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Coinfection as a challenge of the health system. TB / HIV / AIDS - prevention and treatment in Ghana].","authors":"Ernest Kenu, Michael Käser","doi":"10.1002/pauz.201100453","DOIUrl":"https://doi.org/10.1002/pauz.201100453","url":null,"abstract":"","PeriodicalId":19878,"journal":{"name":"Pharmazie in Unserer Zeit","volume":"41 1","pages":"58-63"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/pauz.201100453","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30548545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christine M Topf, Johannes Schiebel, Caroline Kisker, Ulrike Holzgrabe
Seit Jahren begegnet uns allen Triclosan in vielen Alltagsgegenstanden, in denen es uber eine Hemmung der Fettsauresynthese antibakteriell wirksam ist; daruber hinaus sind weitere schwach inhibierende Naturstoffe aus Bakterien und Pilzen bekannt. Die Optimierung dieser Substanzen stellt einen vielversprechenden Ansatz zur Entwicklung neuer Antituberkulotika dar, wobei sowohl die Selektivitat fur die mykobakterielle Fettsauresynthese als auch die Aufnahme der Substanzen in das Mykobakterium eine grose Hurde darstellen.
{"title":"[Old and new anti-mycobacterial drugs. Fatty acid synthesis as a target].","authors":"Christine M Topf, Johannes Schiebel, Caroline Kisker, Ulrike Holzgrabe","doi":"10.1002/pauz.201100454","DOIUrl":"https://doi.org/10.1002/pauz.201100454","url":null,"abstract":"Seit Jahren begegnet uns allen Triclosan in vielen Alltagsgegenstanden, in denen es uber eine Hemmung der Fettsauresynthese antibakteriell wirksam ist; daruber hinaus sind weitere schwach inhibierende Naturstoffe aus Bakterien und Pilzen bekannt. Die Optimierung dieser Substanzen stellt einen vielversprechenden Ansatz zur Entwicklung neuer Antituberkulotika dar, wobei sowohl die Selektivitat fur die mykobakterielle Fettsauresynthese als auch die Aufnahme der Substanzen in das Mykobakterium eine grose Hurde darstellen.","PeriodicalId":19878,"journal":{"name":"Pharmazie in Unserer Zeit","volume":"41 1","pages":"64-70"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/pauz.201100454","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30548546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[A resistant organism fight with modern weapons. Biology of mycobacteria and new molecular targets].","authors":"Oliver Koch, Paul M Selzer","doi":"10.1002/pauz.201100449","DOIUrl":"https://doi.org/10.1002/pauz.201100449","url":null,"abstract":"","PeriodicalId":19878,"journal":{"name":"Pharmazie in Unserer Zeit","volume":"41 1","pages":"19-26"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/pauz.201100449","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30549255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aus den Staaten der ehemaligen Sowjetunion kommen viele Patienten nach Europa, die an MDR/XDR-Tuberkulose leiden. Auf Grund dieser schwierigen Resistenzlage konnen sie nur in Spezialkliniken fachgerecht und erfolgreich behandelt werden.
{"title":"[Are there any treatment options? Resistance imported from Russia].","authors":"Ralf Mütterlein","doi":"10.1002/pauz.201100455","DOIUrl":"https://doi.org/10.1002/pauz.201100455","url":null,"abstract":"Aus den Staaten der ehemaligen Sowjetunion kommen viele Patienten nach Europa, die an MDR/XDR-Tuberkulose leiden. Auf Grund dieser schwierigen Resistenzlage konnen sie nur in Spezialkliniken fachgerecht und erfolgreich behandelt werden.","PeriodicalId":19878,"journal":{"name":"Pharmazie in Unserer Zeit","volume":"41 1","pages":"73-5"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/pauz.201100455","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30548547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Grußwort des Präsidenten","authors":"D. Steinhilber","doi":"10.1002/PAUZ.201290001","DOIUrl":"https://doi.org/10.1002/PAUZ.201290001","url":null,"abstract":"","PeriodicalId":19878,"journal":{"name":"Pharmazie in Unserer Zeit","volume":"47 1","pages":"2-2"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88763610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}