Parasitology International最新文献

{"title":"Coinfection of large yellow croaker Larimichthys crocea by Trypanosoma sp. (Euglenozoa: Kinetoplastea) and Ceratomyxa xiangshanensis n. sp. (Cnidaria: Myxosporea) in offshore net cage systems in the East China Sea","authors":"Bo Zhang ,&nbsp;Xiao Xie ,&nbsp;Chao Zheng ,&nbsp;Xingyu Wang ,&nbsp;Kurt Buchmann ,&nbsp;Fei Yin","doi":"10.1016/j.parint.2025.103167","DOIUrl":"10.1016/j.parint.2025.103167","url":null,"abstract":"<div><div>The large yellow croaker, <em>Larimichthys crocea</em>, is an indigenous fish in the East China Sea and a highly ranked marine fish species, primarily reared in the coastal waters of the East China Sea. Recently, infections with hemoflagellates (causing trypanosomiasis) in this fish species were detected on the southeast coast of China; however, the pathogenicity has not been established. Here, an outbreak of mass mortality in <em>L. crocea</em> farmed in Zhejiang province is reported with coinfection of hemoflagellates and myxosporeans. For hemoflagellates, blood smears reveal elongated trypomastigotes measured 20.5 ± 3.4 μm × 1.9 ± 0.4 μm, and an anterior free flagellum is 11.9 ± 2.6 μm in length. Molecular analysis of the small subunit ribosomal sequence showed that the isolated hemoflagellate is conspecific with the <em>Trypanosoma</em> sp. previously reported in the Fujian province, which suggests a neglected transmission event along with transboundary fish delivery. Besides, combining morphological disparities with no more than 98.09 % molecular identity, the biliary myxosporean is regarded as a novel species, <em>Ceratomyxa xiangshanensis</em> n. sp. Histological examination of infected fish tissues showed trypanosome-associated pigment aggregation in melanoma-macrophage centers of the spleen and kidney. The subcutaneous tissue of the head is observed with moderate inflammatory infiltration in the dermis. We suggest that the year-round feeding operation and seasonal fish delivery may favor native circulation and transboundary transmission of these endoparasites. This work expands our knowledge of the parasite fauna harbored in reared <em>L. crocea</em> and frames the importance of routine surveillance for emerging parasitic diseases.</div></div>","PeriodicalId":19983,"journal":{"name":"Parasitology International","volume":"111 ","pages":"Article 103167"},"PeriodicalIF":1.9,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145041080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to First report of Saccocoelioides nanii (Digenea: Haploporidae) infecting an extremophile host, Jenynsia sulfurica (Cyprinodontiformes: Anablepidae) Parasitology International, Volume 110 (2026), 103148","authors":"Macarena S. De Martino ,&nbsp;Guillermo E. Teran ,&nbsp;Patricia M.C. Romero ,&nbsp;Felipe Alonso ,&nbsp;Melisa Moncada ,&nbsp;German Reig Cardarella ,&nbsp;Gaston Aguilera ,&nbsp;Martin M. Montes","doi":"10.1016/j.parint.2025.103163","DOIUrl":"10.1016/j.parint.2025.103163","url":null,"abstract":"","PeriodicalId":19983,"journal":{"name":"Parasitology International","volume":"111 ","pages":"Article 103163"},"PeriodicalIF":1.9,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145030282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neospora caninum, Sarcocystis spp. and Toxoplasma gondii infections and their relationship with milk production in goats from Argentina","authors":"K.D. Steffen ,&nbsp;L. Gortari Castillo ,&nbsp;M.L. Gos ,&nbsp;M.C. Venturini ,&nbsp;R.O. Arias ,&nbsp;G. Moré","doi":"10.1016/j.parint.2025.103165","DOIUrl":"10.1016/j.parint.2025.103165","url":null,"abstract":"<div><div>The apicomplexan protozoa <em>Neospora caninum, Sarcocystis</em> spp. and <em>Toxoplasma gondii</em> are worldwide distributed. Goat infections with these protozoans are frequent, although the relationship with milk production is unknown. The aim of this study was to evaluate and relate the antibodies titers to <em>N. caninum</em>, <em>Sarcocystis</em> spp. and <em>T. gondii</em> with the goat milk production. The study was conducted in two commercial dairy goat farms located in the province of Buenos Aires, Argentina. A total of 336 Saanen breed goats were evaluated (146 goats of E1 and 190 goats of E2). The total production per lactation was calculated and adjusted to 240 lactation days in milliliters. Blood samples obtained and the age, number of lactations, body condition, and FAMACHA© degree were recorded. Sera were tested for <em>N. caninum</em>, <em>Sarcocystis</em> spp. and <em>T. gondii</em> antibodies by IFAT, starting at 1:100 for <em>N. caninum</em> and <em>T. gondii</em> IFATs, and at 1:50 for <em>Sarcocystis</em> spp., and all three IFATs from each animal were processed at the same time to final titer. The overall seroprevalence of <em>N. caninum, Sarcocystis</em> spp. and <em>T. gondii</em> was 81.8 % (275/336), 85.1 % (286/336) and 66.7 % (224/336), respectively. Forty-nine percent (164/336) of goats were seropositive to three IFATs, 37.5 % (126/336) to two and 12.2 % (41/336) to only one. Similar <em>N. caninum</em> and <em>Sarcocystis</em> spp. seroprevalences were observed in E1 (80.1 and 88.4 %) compared to E2 (83.1 and 82.6 %), respectively. A higher <em>T. gondii</em> seroprevalence was detected in E1 (80.1 %) than E2 (56.3 %). A small group of 16 goats with higher IFAT titers to <em>T. gondii</em>, produced significantly less milk (85.3 L) than the rest. No significant milk productivity differences were found in goats seropositive and negative to only one, two or all three IFATs when analyzed within age and/or ordinal lactation number groups. Our results indicate a low association of seropositivity to these protozoans with goat milk production.</div></div>","PeriodicalId":19983,"journal":{"name":"Parasitology International","volume":"111 ","pages":"Article 103165"},"PeriodicalIF":1.9,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Soil-transmitted helminth eggs in public areas of Azores archipelago, Portugal","authors":"Romana Teixeira ,&nbsp;João Lozano ,&nbsp;Isilda Flor ,&nbsp;Carlos Pinto ,&nbsp;Maria Constança Pomba ,&nbsp;Luís Madeira de Carvalho","doi":"10.1016/j.parint.2025.103166","DOIUrl":"10.1016/j.parint.2025.103166","url":null,"abstract":"<div><div>In the Azores archipelago, data regarding environmental contamination by soil-transmitted helminths (STHs) is inexistent till the moment. The current study aimed to assess the environmental contamination with helminth eggs, in soil samples collected from public parks/gardens and beaches from three islands belonging to the Azores archipelago (Portugal): Faial, Terceira and São Miguel. Between June–December 2024, a total of 37 soil samples were collected from 26 public parks/gardens and 11 public beaches, and processed using the Mini-FLOTAC method to calculate parasites' prevalences and burdens (eggs/oocysts per gram of soil, EPG/OPG). Overall, a total of 35 % of the sampled sites were contaminated with helminth eggs, with the environmental contamination being higher in public parks or gardens (46 %), in comparison with beach areas (9 %). The majority of positive sites were contaminated with <em>Toxocara</em> spp. eggs (30 %), followed by Ancylostomatidae (11 %) and <em>Trichuris</em> spp. (11 %) eggs. São Miguel and Terceira islands presented higher rates of soil contamination, when compared to Faial Island. The overall helminth egg intensity was the following: <em>Toxocara</em> spp. (157 EPG), <em>Trichuris</em> spp. (59 EPG) and Ancylostomatidae (38 EPG). Faial island presented the lowest EPG levels, regarding all parasite species, being <em>Toxocara</em> spp. EPG levels significantly lower than the remaining islands surveyed (<em>p</em> = 0.02). The present study provides new and relevant data concerning environmental contamination by STHs with zoonotic potential in the Azores archipelago, and revealed that the analysis of soil samples is an important approach to be included in integrated pet parasite control programs.</div></div>","PeriodicalId":19983,"journal":{"name":"Parasitology International","volume":"111 ","pages":"Article 103166"},"PeriodicalIF":1.9,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145005383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Morphological and molecular data reveal a new genus and species from the family Transvenidae (Echinorhynchida: Palaeacanthocephala) from Bahía de Todos los Santos, Northeast Pacific, Mexico","authors":"Rogelio Aguilar-Aguilar ,&nbsp;Marcelo Tonatiuh González-García ,&nbsp;Martín García-Varela","doi":"10.1016/j.parint.2025.103164","DOIUrl":"10.1016/j.parint.2025.103164","url":null,"abstract":"<div><div>Echinorhynchids are a group of globally distributed acanthocephalan parasites mainly of freshwater, brackish and marine fishes and occasionally, reptiles and amphibians. During several parasitology surveys in the Gulf of Mexico and Northeast Pacific, Mexico, acanthocephalans were recovered from two marine fish species. The specimens from the Gulf of Mexico were identified as <em>Caballerorhynchus lamothei</em> (Cavisomidae), a typical parasite of the striped mojarra, whereas adult acanthocephalans from the Northeast Pacific, Mexico, from the Garibaldi fish exhibited morphological characteristics belonging to the family Transvenidae. Sequences from the small (SSU) and large (LSU) subunits of ribosomal DNA and cytochrome c oxidase subunit 1 (cox 1) of mitochondrial DNA were obtained for both species. The new sequences were aligned with other sequences available in the GenBank dataset from Echinorhynchida. Phylogenetic trees inferred with the combined (SSU + LSU), concatenated (SSU + LSU+ cox 1), and cox 1 datasets consistently placed the two species into two independent lineages. The species <em>C. lamothei</em> from Cavisomidae was placed in a clade together with members from Spinulacorpidae, Rhadinorhynchidae and Transvenidae, suggesting that Cavisomidae is paraphyletic. The unidentified specimens were nested inside a clade formed by members of Transvenidae. Morphologically, the new samples presented a combination of unique diagnostic traits, which was not observed in other members of the Transvenidae family. Therefore, the genus <em>Darwinorhynchus</em> was created to accommodate a new species named herein as <em>Darwinorhynchus bajacaliforniaensis</em> n. gen., n. sp. The current record from a transvenid acanthocephalan expands its distribution range to the northern Pacific in the Americas, Indian Ocean and Arabian Gulf.</div></div>","PeriodicalId":19983,"journal":{"name":"Parasitology International","volume":"111 ","pages":"Article 103164"},"PeriodicalIF":1.9,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145005055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First molecular characterization and species validation of Toxocara alienata (Rudolphi 1819) (Nematoda: Ascarididae), from a crab-eating raccoon (Procyon cancrivorus)","authors":"Gustavo Macêdo do Carmo ,&nbsp;Lorena Gisela Ailán-Choke ,&nbsp;Hassan Jerdy ,&nbsp;Hermínio Ismael de Araújo-Júnior ,&nbsp;Felipe Bisaggio Pereira","doi":"10.1016/j.parint.2025.103160","DOIUrl":"10.1016/j.parint.2025.103160","url":null,"abstract":"<div><div><em>Toxocara alienata</em> infects racoons and wild pigs in South America and its taxonomy is important to distinguish the species from closely related zoonotic congeners, such as <em>T. canis</em>. This study provides the first genetic characterization of <em>T. alienata</em> from the Brazilian Amazon, along with a comprehensive morphological description, to clarify its distinction from the closely related <em>T. canis</em>. Nematodes were observed using light and scanning electron microscopy and genetically characterized based on barcode COI mtDNA. A phylogeny was reconstructed using Bayesian inference and different species delimitation methods (PTP, bPTP, ASAP, GMYC) were performed for robust species validation. Specimens were identified as <em>T</em>. <em>alienata</em> based on a somewhat narrow cervical alae; male with equal, alate spicules, shorten than 1 mm, 28 pairs of caudal papillae (24 subventral precloacal pairs and 4 postcloacal pairs) and a protruded well-developed precloacal lip with an unpaired papilla on it, which was observed for the first time in the species. These morphological features can differentiate <em>T. alienata</em> from <em>T. canis</em> mainly regarding number and arrangement of postcloacal papillae, structure of precloacal lip and the presence of the unpaired papilla. In the phylogeny, <em>T. alienata</em> represented an independent lineage, sister to a clade formed by <em>T. canis</em> sequences. All species delimitation methods validated <em>T</em>. <em>alienata</em> as a specific entity, different from <em>T. canis</em>. The present results, including the first genetic characterization of <em>T. alienata</em>, reinforce its validation and provide crucial data for future taxonomic, epidemiological and ecological works on Toxocarinae.</div></div>","PeriodicalId":19983,"journal":{"name":"Parasitology International","volume":"111 ","pages":"Article 103160"},"PeriodicalIF":1.9,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145005053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Systemic infection of Prohemistomum vivax and Cyanodiplostomum encysted metacercariae in African catfish (Clarias gariepinus) from a heavily polluted drain at Giza, Egypt: morphological, molecular and histopathological study","authors":"Alaa Eldin Eissa ,&nbsp;Olfat A. Mahdy ,&nbsp;Eman M. Abouelhassan ,&nbsp;Rabia A. El Zlitne ,&nbsp;Abdulsalam Abu Mhara ,&nbsp;Asmaa K. Al-Mokaddem ,&nbsp;Eman H. Rashwan ,&nbsp;Reham H. Ragab ,&nbsp;Nehal A. Younis","doi":"10.1016/j.parint.2025.103159","DOIUrl":"10.1016/j.parint.2025.103159","url":null,"abstract":"<div><div>Aquatic environmental pollution could be a direct trigger of infection through cercarial invasion to skin / gills or indirectly as a predisposing factor that damage the physical barriers of targeted fish resulting in high intensities of EMC infections in all fish vital organs. In the current study, a total of 150 African catfish (<em>Clarias gariepinus</em>) were randomly collected from Mariotteya drain all the way through the Egyptian township of Shabramant located at the historical heart of Giza. Catfish samples were collected in mid-summer during the period from June to July 2024. A well-documented surge in unionized ammonia, water alkalinity, marked decline in dissolved oxygen together with decreased transparency were signaling a chronic case of agricultural and municipal pollution in which all physical mucosal immunological barriers were harshly suppressed. This environmental disruption has resulted in cellular, biological and pathological alterations in which the invasion of digenean cercariae was favored as documented in the histopathological sections made from affected tissues. Parasitological examination revealed the presence of two distinct EMC belonging to <em>Prohemistomum vivax</em> and <em>Cyanodiplostomum</em> spp. which were presumptively identified using the regular morpho-taxonomical methods and confirmed utilizing the sequencing of the ITS2 rDNA gene which is considered good marker in the differentiation between the digenean species and the phylogeny analysis. Histopathological examination of sampled fish tissues has revealed that EMC infection was not only limited to fish musculatures, yet it extends to internal organs including spleen and kidney to present a unique form of systemic EMC infection. EMC were documented within the splenic &amp; renal tissues with remarkable activation of melanomacrophage centers (MMC) denoting the pathophysiological response of hematopoietic tissues to the EMC invasion. The current study sheds light on the growing danger of aquatic pollution and its direct trigger of zoonotic metacercarial spread through the consumption of infected fish flesh.</div></div>","PeriodicalId":19983,"journal":{"name":"Parasitology International","volume":"111 ","pages":"Article 103159"},"PeriodicalIF":1.9,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145006450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Observation of Giardia duodenalis infection in Mongolian gerbils: Cysts isolated from bovine feces","authors":"Yifei Li ,&nbsp;Hongsen Yu ,&nbsp;Xiaolin Zeng ,&nbsp;Tianyu Li ,&nbsp;Xuhai Li ,&nbsp;Ting Wu ,&nbsp;Xiangyu Yan ,&nbsp;Qixi Li ,&nbsp;Chenhan Bu ,&nbsp;Qi Sun ,&nbsp;Jingjing Wang ,&nbsp;Ershun Zhou ,&nbsp;Zhengtao Yang","doi":"10.1016/j.parint.2025.103151","DOIUrl":"10.1016/j.parint.2025.103151","url":null,"abstract":"<div><div>Assemblage E of <em>Giardia duodenalis</em>, primarily infecting ruminants, has been relatively understudied both in vivo and in vitro. Due to unsuccessful attempts at in vitro cultivation, this study focused on establishing an economical, stable, and clinically relevant experimental animal model for Assemblage E infections. Cysts were purified from bovine feces via 33 % zinc sulfate flotation, with Assemblage E identity confirmed by gdh gene sequencing. Nine five – day - old Mongolian gerbils were randomly allocated into control group (PBS), low-dose group (5 × 10⁴cysts), and high-dose group (1 × 10⁵cysts) averagely, Gerbils were received bovine-derived Assemblage E cysts via oral gavage, all infected subjects were undergone of necropsy at 8 days post-infection. Longitudinal monitoring result demonstrated that gerbils in infected groups exhibited growth retardation and excreted soft feces compared with controls. Histopathological examination result revealed that massive trophozoite were colonized on atrophied duodenal villi, meanwhile, enterocyte boundary was effacement in high-dose group. Scanning electron microscopy (SEM) detection result were showed that the trophozoite density decline along the intestinal tract: duodenum&gt;jejunum&gt;ileum. That could be confirmed the characteristic of trophozoite duodenal tropism. Encystation dynamics analysis was identified bile acid-mediated morphological transformation in the ileum through SEM, the process of encystation with trophozoite rounding, ventral disc degeneration and cyst wall formation. These results could recapitulate the complete life cycle of Assemblage E in experimental hosts, this study provided a validated model for investigating host-specific about giardiasis pathogenesis.</div></div>","PeriodicalId":19983,"journal":{"name":"Parasitology International","volume":"111 ","pages":"Article 103151"},"PeriodicalIF":1.9,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145005054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Open defaecation and hygiene practices in relation to Soil-Transmitted Helminths in the advent of Mass Drug Administration in Ona-Ara, Ibadan, Oyo State, Nigeria","authors":"D.A. Oyebamiji,&nbsp;C.Y. Ajayi,&nbsp;B.O. Banwo","doi":"10.1016/j.parint.2025.103149","DOIUrl":"10.1016/j.parint.2025.103149","url":null,"abstract":"<div><div>Soil-Transmitted Helminths (STHs) infections are one of the Neglected Tropical Diseases (NTDs) in tropical Africa and have been targeted for possible elimination in the year 2030. This study was conducted between August 2022 and July 2023 in Ona-Ara Local Government Area (LGA), Ibadan, Nigeria, to investigate the effects of Open Defaecation (OD), Water, Sanitation, and Hygiene (WASH) practices on STHs status in the advent of mass drug administration in the communities. 450 structured questionnaires covering demographics (age, sex), and WASH practices were given to consenting participants. 450 faecal samples from consenting participants and 1350 soil samples from the environment were collected from five different communities: Akanran, Olorunda, Idi-Ose, Amuloko, and Ore-Meji in the LGA. Parasites were extracted from the contaminated soil using floatation and modified Baermann methods while sedimentation method was used to detect parasites in the faecal samples and quantified by Kato-Katz techniques. Data were analyzed using descriptive, regression and ANOVA at α _0.05. 59.8 % of the participants did not have access to potable water while 40.2 % claimed drinking water directly from the tap. Furthermore, 42.2 % had water closet, 41.1 % pit latrine, and 16.7 % practised OD of which 60.8 % are infected with STH. In terms of hygiene practices, 6.7 % reported that they do not wash with soap and water after defaecation, while 43.8 % claimed that they use tissue paper or water occasionally. The parasites prevalence in faecal samples collected from participants was 38 % in Ona Ara and the overall intensity was 265 per gram of faeces. <em>Ascaris</em> had the highest intensity of STH (300epg), followed by hookworm (210epg), <em>Trichuris</em> (50epg), and the least <em>Strongyloides</em> (32epg). The variation in the distribution of parasites was significant at χ² = 75.21, <em>p</em> ≤ 0.05. 52.1 % of the sampled soil had at least one STH parasites and <em>Strongyloides</em> larvae was found to have highest prevalence in soil samples collected in the following locations: Akanran (35.8 %), Olorunda (37.8 %), Amuloko (39.4 %), and Idi-Ose (59.3 %) whereas, hookworm larvae had highest prevalence of 60.7 % in Ore-Meji. There is continuous transmission of STH among the populations living in Ona-Ara and the soil environment owing to OD and the hygiene practices. One Health Approach (animal, environment, and man) studies should be further carried out in the communities.</div></div>","PeriodicalId":19983,"journal":{"name":"Parasitology International","volume":"110 ","pages":"Article 103149"},"PeriodicalIF":1.9,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144922643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Atypical presentation of Enterobius vermicularis in a cognitively impaired elderly patient: A case report","authors":"Shoichi Shimizu ,&nbsp;Masayuki Kamochi ,&nbsp;Yasuhide Urakami ,&nbsp;Yoshio Osada","doi":"10.1016/j.parint.2025.103150","DOIUrl":"10.1016/j.parint.2025.103150","url":null,"abstract":"<div><div><em>Enterobius vermicularis</em> infection (enterobiasis) is a common intestinal parasitosis, typically characterized by perianal pruritus, and is most prevalent in children. Diagnosing enterobiasis in cognitively impaired individuals, who may not report typical symptoms, poses a diagnostic challenge. We report the case of an 86-year-old Japanese woman with cognitive impairment who was admitted for a tibial fracture. During a routine diaper change, several motile, thread-like organisms were incidentally observed in her perianal and perivaginal areas. Microscopic examination identified the organisms as gravid female <em>E. vermicularis</em>. The patient reported no pruritus ani or insomnia, and was successfully treated with a two-dose regimen of pyrantel pamoate. The follow-up adhesive tape tests confirmed clearance of the parasites. This case highlights that enterobiasis can be clinically silent in elderly patients with cognitive impairment, a population at increased risk due to potential difficulties with hygiene and an inability to report symptoms. Clinicians and caregivers should remain alert to enterobiasis in cognitively impaired elderly patients to ensure timely diagnosis and prevent transmission.</div></div>","PeriodicalId":19983,"journal":{"name":"Parasitology International","volume":"110 ","pages":"Article 103150"},"PeriodicalIF":1.9,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144922644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}