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On "A Core Set of Outcome Measures to Assess Physical Function for Adults Participating in Physical Therapist Treatment in the Hospital: A Clinical Practice Guideline." Mayer KP, Johnson AM, Smith DJ, et al. Phys Ther. 2025;105(6):pzaf076. doi: 10.1093/ptj/pzaf076. 关于“一套评估参与医院物理治疗师治疗的成人身体功能的核心结果措施:临床实践指南”。Mayer KP, Johnson AM, Smith DJ,等。物理学报,2015;105(6):pzaf076。doi: 10.1093 / ptj / pzaf076。
IF 3.3 4区 医学 Q1 ORTHOPEDICS Pub Date : 2026-01-23 DOI: 10.1093/ptj/pzag004
Christiane S Perme, Monica Silva Damasceno, Esther Cecilia Wilches-Luna, Ricardo Kenji Nawa
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引用次数: 0
From Theory to Practice: A Mixed-Method Evaluation of a Program to Implement High Intensity-Rehabilitation in Skilled Nursing Facilities. 从理论到实践:在熟练护理机构中实施高强度康复计划的混合方法评估。
IF 3.3 4区 医学 Q1 ORTHOPEDICS Pub Date : 2026-01-23 DOI: 10.1093/ptj/pzag008
Lauren A Hinrichs-Kinney, Mattie Pontiff, Katie A Butera, Emma H Beisheim-Ryan, Dawn M Magnusson, Jennifer E Stevens-Lapsley

Importance: Implementing evidence-based dosing of rehabilitation in skilled nursing facilities (SNFs) is essential to improve functional outcomes in a medically-complex population.

Objective: The objective was to evaluate an implementation program promoting high-intensity resistance rehabilitation (HIR) in SNFs by (1) measuring proximal (clinician knowledge, self-efficacy, and HIR perspective) and distal (HIR adoption and implementation) outcomes; (2) exploring how the program influenced distal outcomes (program processes); and (3) investigating clinician factors influencing HIR implementation.

Design: The design was a prospective convergent mixed-methods, theory-driven program evaluation.

Setting: This study was conducted across 8 rural Department of Veterans Affairs SNFs.

Participants: Rehabilitation clinicians (n = 38) and leaders (n = 16) were included.

Interventions or exposures: All sites received a multicomponent implementation program promoting HIR.

Main outcomes and measures: Validated questionnaires assessed HIR perspective (Perceived Characteristics of Intervention Scale) and adoption (Commitment to Change Scale). Study-specific questionnaires measured clinician HIR knowledge, self-efficacy, and implementation. Interviews and focus groups explored program processes and clinician factors.

Results: The program improved clinician HIR knowledge, self-efficacy, and perspective, leading to acceptable adoption rates. Implementation was marginally affected. Only clinician perspective correlated with adoption (ρ = 0.47). Qualitatively, the program supported distal outcomes by keeping HIR at the forefront of clinicians' mind, fostering positive outcome expectations, and enhancing team cohesion and accountability. Clinician creativity, adaptability, resilience, professional discipline, and previous experience influenced implementation.

Conclusion: The program influenced HIR adoption primarily by enhancing clinicians' positive perspectives of HIR. Future efforts could strengthen implementation by fostering team cohesion, accountability, and clinician creativity while also assessing environmental factors.

Relevance: Effective HIR implementation can optimize patient outcomes. Strategies that enhance clinician perspective and creativity, keep HIR at the forefront, and foster team cohesion and accountability may improve adoption. Additionally, assessing and addressing environmental factors may further support sustainable integration of HIR into clinical practice.

重要性:在熟练护理机构(snf)实施循证给药的康复治疗对于改善医疗复杂人群的功能结果至关重要。目的:通过(1)测量近端(临床医生知识、自我效能感和HIR观点)和远端(HIR采用和实施)结果来评估促进snf高强度抵抗康复(HIR)的实施方案;(2)探索节目如何影响远端结果(节目过程);(3)调查影响HIR实施的临床因素。设计:设计是一个前瞻性的融合混合方法,理论驱动的方案评估。背景:本研究在8个农村退伍军人事务部snf中进行。参与者:康复临床医生38名,康复领导16名。干预或暴露:所有地点都接受了促进HIR的多组件实施计划。主要结果和测量方法:经验证的问卷评估了HIR视角(干预感知特征量表)和采纳程度(改变承诺量表)。研究特定的问卷测量临床医生的HIR知识,自我效能和实施。访谈和焦点小组探讨了项目流程和临床医生因素。结果:该项目提高了临床医生的HIR知识、自我效能和观点,导致了可接受的采用率。执行受到轻微影响。只有临床医生的观点与收养相关(ρ = 0.47)。从质量上讲,该项目通过将HIR放在临床医生的最前沿来支持远端结果,培养积极的结果预期,并增强团队凝聚力和责任。临床医生的创造力、适应性、弹性、专业纪律和以前的经验影响了实施。结论:该计划主要通过提高临床医生对HIR的积极看法来影响HIR的采用。未来的努力可以通过培养团队凝聚力、责任感和临床医生的创造力来加强实施,同时也要评估环境因素。相关性:有效的HIR实施可以优化患者的预后。提高临床医生的观点和创造力、保持HIR处于前沿、培养团队凝聚力和问责制的策略可能会提高采用率。此外,评估和解决环境因素可能进一步支持HIR与临床实践的可持续整合。
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引用次数: 0
Author Response to Perme Et al. 作者对Perme等人的回应。
IF 3.3 4区 医学 Q1 ORTHOPEDICS Pub Date : 2026-01-23 DOI: 10.1093/ptj/pzag005
Kirby P Mayer, Audrey M Johnson, Sowmya Kumble, Traci L Norris
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引用次数: 0
Predictors of Functional Recovery in Individuals Exposed to Late-Stage Exercise Programs after Total Knee Replacement: A Secondary Analysis of a Randomized Controlled Trial. 全膝关节置换术后进行后期运动的个体功能恢复的预测因素:一项随机对照试验的二次分析。
IF 3.3 4区 医学 Q1 ORTHOPEDICS Pub Date : 2026-01-22 DOI: 10.1093/ptj/pzag006
Cristiane R Carlesso, Clair Smith, Charity G Patterson, Allyn M Bove, Sara R Piva

Importance: Total knee replacement (TKR) is common for advanced cartilage degeneration. Often, functional limitations persist, and late-stage exercise (2-4 months after TKR) may improve recovery.

Objective: The objective of this study was to identify predictors of late-stage functional recovery after TKR and their variations by exercise program.

Design: This study was a secondary analysis of a randomized controlled trial.

Setting: The settings were 1 physical therapy clinic and 4 community centers in Allegheny County, Pennsylvania.

Participants: The study included 199 individuals (mean age = 70 years; body mass index = 31 kg/m2; 60% women).

Interventions: Interventions were physical therapy exercises, community-based exercises, and usual care.

Main outcome and measures: The main outcome was functional recovery at 6 months after intervention. Functional recovery was defined as ≥50% improvement on the Western Ontario and McMaster Universities Osteoarthritis Index physical function subscale, at least somewhat better on the Global Rating of Change, and ≥ 20% improvement on ≥2 performance-based tests. Predictors were identified using logistic regression. Odds ratios (ORs) and 95% confidence intervals (CIs) were reported.

Results: In the entire cohort, 33% of participants achieved functional recovery, including 42% in the physical therapy group and 38% in the community group. Overall, better baseline health (odds ratio [OR] = 2.70 [95% CI = 1.34-5.47]), discharge to home (OR = 6.24 [95% CI = 1.94-20.09]), and higher Western Ontario and McMaster Universities Osteoarthritis Index pain subscale scores (OR = 1.22 [95% CI = 1.07-1.40]) predicted functional recovery. In the physical therapy group (n = 83), positive predictors were better health (OR = 4.40 [95% CI = 1.20-16.06]), discharge to home (OR = 11.67 [95% CI = 2.01-67.76]), regular use of nonsteroidal antiinflammatory drugs (OR = 3.76 [95% CI = 1.11-12.78]), and as-needed use of analgesics (OR = 10.53 [95% CI = 1.75-63.48]). Negative predictors, associated with a lower likelihood of recovery, were regular use of salicylates (OR = 0.22 [95% CI = 0.07-0.74]) and greater use of pain-coping strategies (OR = 0.51 [95% CI = 0.29-0.89]). No predictors were identified in the community group (n = 76).

Conclusions: Better baseline health, discharge to home after TKR, and higher pain levels predicted functional recovery. Physical therapy provided additional benefits for a subset of participants.

Relevance: This evidence helps clinicians set realistic functional recovery expectations and strategies to facilitate function late after TKR.

重要性:全膝关节置换术(TKR)是常见的晚期软骨退变。通常,功能限制持续存在,后期运动(TKR后2-4个月)可以改善恢复。目的:本研究的目的是确定TKR后晚期功能恢复的预测因素及其随运动计划的变化。设计:本研究为随机对照试验的二次分析。实验环境:实验环境为宾夕法尼亚州阿勒格尼县的1个物理治疗诊所和4个社区中心。参与者:该研究包括199人(平均年龄= 70岁,体重指数= 31 kg/m2, 60%为女性)。干预措施:干预措施包括物理治疗练习、社区练习和日常护理。主要观察指标:干预后6个月功能恢复为主要观察指标。功能恢复的定义为:在西安大略和麦克马斯特大学骨关节炎指数身体功能量表中改善≥50%,在全球变化评分中至少有所改善,在≥2项基于性能的测试中改善≥20%。使用逻辑回归确定预测因子。报告了优势比(ORs)和95%置信区间(CIs)。结果:在整个队列中,33%的参与者实现了功能恢复,其中物理治疗组为42%,社区组为38%。总体而言,较好的基线健康(比值比[OR] = 2.70 [95% CI = 1.34-5.47])、出院回家(OR = 6.24 [95% CI = 1.94-20.09])和较高的西安大略大学和麦克马斯特大学骨关节炎指数疼痛亚量表评分(OR = 1.22 [95% CI = 1.07-1.40])预示着功能恢复。在物理治疗组(n = 83)中,阳性预测因子为健康状况较好(OR = 4.40 [95% CI = 1.20-16.06])、出院回家(OR = 11.67 [95% CI = 2.01-67.76])、定期使用非甾体类抗炎药(OR = 3.76 [95% CI = 1.11-12.78])和按需使用镇痛药(OR = 10.53 [95% CI = 1.75-63.48])。与较低康复可能性相关的负面预测因子是经常使用水杨酸盐(OR = 0.22 [95% CI = 0.07-0.74])和更多地使用疼痛应对策略(OR = 0.51 [95% CI = 0.29-0.89])。社区组中未发现预测因子(n = 76)。结论:较好的基线健康状况、TKR术后出院和较高的疼痛水平预示着功能恢复。物理治疗为一部分参与者提供了额外的好处。相关性:这一证据有助于临床医生制定现实的功能恢复预期和策略,以促进TKR后晚期的功能恢复。
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引用次数: 0
Physical Therapy and Occupational Therapy in Acute Care: Association of Timing and Frequency with 30-Day Readmission after Ischemic Stroke. 急性护理中的物理治疗和职业治疗:时间和频率与缺血性卒中后30天再入院的关系。
IF 3.3 4区 医学 Q1 ORTHOPEDICS Pub Date : 2026-01-21 DOI: 10.1093/ptj/pzag007
Jessica Edelstein, Amanda Hoffman, Darcie M Luby, Joseph Rosenthal, Anne Deutsch, James E Graham

Importance: Reducing 30-day hospital readmission rates after ischemic stroke is a national priority, yet optimal rehabilitation service delivery strategies in acute care are unclear. Physical therapy and occupational therapy are essential for functional recovery, discharge planning, and readmission prevention, but the association between service delivery factors and readmission risk remains uncertain.

Objective: The objective was to evaluate the relationship between the timing and frequency of physical therapy and occupational therapy in acute care and 30-day readmission rates among patients with ischemic stroke.

Design: This was an observational cross-sectional study using electronic medical records from January 2018 to December 2021.

Setting: The study was conducted within a 13-hospital health system in Colorado.

Participants: Patients with a primary diagnosis of ischemic stroke (N = 1545) were included. Inclusion required receiving physical therapist or occupational therapist treatment, while exclusions included evaluation-only visits, discharge to hospice, leaving against medical advice, interhospital transfers, or death within 30 days. Final samples included 979 physical therapy and 713 occupational therapy patients, stratified by discharge destination (home vs postacute rehabilitation).

Exposures: Rehabilitation service delivery factors were: (1) time to evaluation: days from admission to first therapy evaluation; (2) time to treatment: days from evaluation to first therapy session; and (3) therapy frequency: total number of therapy sessions (1-2, 3-4, or ≥ 5). Separate analyses were conducted for physical therapist and occupational therapist services.

Main outcomes: The primary outcome was 30-day hospital readmission.

Results: Among patients discharged home, fewer days between physical therapist evaluation and treatment were associated with reduced odds of readmission (OR = 1.105, 95% CI = 1.003-1.217). Higher occupational therapy session frequency was linked to lower readmission odds (≥5 sessions: OR = 0.17, 95% CI = 0.029-0.994). After adjustment for length of stay, the association between occupational therapy frequency and readmission was attenuated, whereas the association between time to physical therapy evaluation and readmission remained significant. No significant associations were found in patients discharged to postacute rehabilitation facilities.

Conclusions and relevance: Early physical therapist treatment and frequent occupational therapy sessions were associated with reduced 30-day readmission risk for patients discharged home. Optimizing acute care rehabilitation service delivery is essential to improving postdischarge outcomes.

重要性:减少缺血性卒中后30天的再入院率是国家的优先事项,但在急性护理中最佳的康复服务提供策略尚不清楚。物理治疗和职业治疗对于功能恢复、出院计划和再入院预防至关重要,但服务提供因素与再入院风险之间的关系仍不确定。目的:目的是评估急性护理中物理治疗和职业治疗的时间和频率与缺血性卒中患者30天再入院率之间的关系。设计:这是一项观察性横断面研究,使用2018年1月至2021年12月的电子病历。环境:该研究是在科罗拉多州13家医院的卫生系统中进行的。参与者:初步诊断为缺血性卒中的患者(N = 1545)被纳入研究。纳入要求接受物理治疗师或职业治疗师治疗,而排除包括仅进行评估的访问、出院到临终关怀、不遵医嘱离开、院间转院或在30天内死亡。最终样本包括979名物理治疗患者和713名职业治疗患者,按出院目的地(家庭与急性康复后)分层。暴露:康复服务提供的因素有:(1)评估时间:从入院到第一次治疗评估的天数;(2)治疗时间:从评估到第一次治疗的天数;(3)治疗频率:治疗总次数(1-2次、3-4次或≥5次)。对物理治疗师和职业治疗师服务进行了单独的分析。主要结局:主要结局为30天再入院。结果:在出院回家的患者中,物理治疗师评估和治疗之间的间隔天数越短,再入院的几率越低(OR = 1.105, 95% CI = 1.003-1.217)。较高的职业治疗频率与较低的再入院几率相关(≥5次:OR = 0.17, 95% CI = 0.029-0.994)。调整住院时间后,职业治疗频率与再入院之间的关联减弱,而物理治疗评估时间与再入院之间的关联仍然显著。在急性后康复机构出院的患者中没有发现显著的关联。结论和相关性:早期物理治疗师治疗和频繁的职业治疗可降低出院患者30天再入院风险。优化急性康复护理服务提供对改善出院后预后至关重要。
{"title":"Physical Therapy and Occupational Therapy in Acute Care: Association of Timing and Frequency with 30-Day Readmission after Ischemic Stroke.","authors":"Jessica Edelstein, Amanda Hoffman, Darcie M Luby, Joseph Rosenthal, Anne Deutsch, James E Graham","doi":"10.1093/ptj/pzag007","DOIUrl":"https://doi.org/10.1093/ptj/pzag007","url":null,"abstract":"<p><strong>Importance: </strong>Reducing 30-day hospital readmission rates after ischemic stroke is a national priority, yet optimal rehabilitation service delivery strategies in acute care are unclear. Physical therapy and occupational therapy are essential for functional recovery, discharge planning, and readmission prevention, but the association between service delivery factors and readmission risk remains uncertain.</p><p><strong>Objective: </strong>The objective was to evaluate the relationship between the timing and frequency of physical therapy and occupational therapy in acute care and 30-day readmission rates among patients with ischemic stroke.</p><p><strong>Design: </strong>This was an observational cross-sectional study using electronic medical records from January 2018 to December 2021.</p><p><strong>Setting: </strong>The study was conducted within a 13-hospital health system in Colorado.</p><p><strong>Participants: </strong>Patients with a primary diagnosis of ischemic stroke (N = 1545) were included. Inclusion required receiving physical therapist or occupational therapist treatment, while exclusions included evaluation-only visits, discharge to hospice, leaving against medical advice, interhospital transfers, or death within 30 days. Final samples included 979 physical therapy and 713 occupational therapy patients, stratified by discharge destination (home vs postacute rehabilitation).</p><p><strong>Exposures: </strong>Rehabilitation service delivery factors were: (1) time to evaluation: days from admission to first therapy evaluation; (2) time to treatment: days from evaluation to first therapy session; and (3) therapy frequency: total number of therapy sessions (1-2, 3-4, or ≥ 5). Separate analyses were conducted for physical therapist and occupational therapist services.</p><p><strong>Main outcomes: </strong>The primary outcome was 30-day hospital readmission.</p><p><strong>Results: </strong>Among patients discharged home, fewer days between physical therapist evaluation and treatment were associated with reduced odds of readmission (OR = 1.105, 95% CI = 1.003-1.217). Higher occupational therapy session frequency was linked to lower readmission odds (≥5 sessions: OR = 0.17, 95% CI = 0.029-0.994). After adjustment for length of stay, the association between occupational therapy frequency and readmission was attenuated, whereas the association between time to physical therapy evaluation and readmission remained significant. No significant associations were found in patients discharged to postacute rehabilitation facilities.</p><p><strong>Conclusions and relevance: </strong>Early physical therapist treatment and frequent occupational therapy sessions were associated with reduced 30-day readmission risk for patients discharged home. Optimizing acute care rehabilitation service delivery is essential to improving postdischarge outcomes.</p>","PeriodicalId":20093,"journal":{"name":"Physical Therapy","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146011416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perspective From the APTA Academy of Geriatric Physical Therapy: The Need for Annual Mobility Assessment for Aging Adults. APTA老年物理治疗学会的观点:老年人年度活动能力评估的必要性。
IF 3.3 4区 医学 Q1 ORTHOPEDICS Pub Date : 2026-01-08 DOI: 10.1093/ptj/pzag002
Michelle G Criss, Jason Dring, Sterling Eckert, Michael Puthoff

During the 2023 Carole B. Lewis Lecture, Michelle Lusardi, DPT, PhD, FAPTA, issued a call to action for the American Physical Therapy Association's Academy of Geriatric Physical Therapy (APTA Geriatrics): to embrace, enact, and evaluate the effectiveness of an annual mobility screen for aging adults. This call highlighted the need to quickly identify preclinical mobility limitations that indicate those at risk for functional decline, falls, and other adverse health outcomes. By moving to a true primary prevention model aimed at identifying preclinical issues, physical therapists can share findings, provide education about the importance of physical activity, and initiate referrals and/or interventions when needed. In response, APTA Geriatrics assembled an Annual Mobility Assessment Task Force to assess this issue and make recommendations. This Perspective Paper summarizes APTA Geriatrics' position on this issue, the Task Force findings, and actions to date. APTA Geriatrics believes that primary prevention efforts to identify risk for avoidable mobility limitations are essential for the physical therapy profession to embrace its mission to transform society by optimizing movement.

在2023年卡罗尔·b·刘易斯讲座期间,FAPTA DPT博士米歇尔·卢萨迪(Michelle Lusardi)向美国物理治疗协会老年物理治疗学会(APTA Geriatrics)发出了行动呼吁:接受、制定并评估老年人年度活动能力筛查的有效性。这一呼吁强调了快速识别临床前活动能力限制的必要性,这些限制表明那些有功能下降、跌倒和其他不良健康结果风险的人。通过转向一种真正的初级预防模式,旨在识别临床前问题,物理治疗师可以分享发现,提供关于体育活动重要性的教育,并在需要时启动转诊和/或干预。对此,APTA老年病科组建了一个年度活动能力评估工作组来评估这一问题并提出建议。这篇观点论文总结了APTA老年病科在这个问题上的立场、工作组的发现和迄今为止的行动。APTA老年病学认为,初级预防努力识别可避免的活动限制风险对于物理治疗专业通过优化运动来改变社会的使命至关重要。
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引用次数: 0
Physical Therapist Interventions for People With Amyotrophic Lateral Sclerosis Across Disease Stages: A Systematic Review of Efficacy. 物理治疗师对肌萎缩性侧索硬化症患者跨疾病阶段的干预:疗效的系统评价。
IF 3.3 4区 医学 Q1 ORTHOPEDICS Pub Date : 2026-01-02 DOI: 10.1093/ptj/pzaf142
Chelsea E Macpherson, Dipti K Wani, Haoyu Li, Vruta Rana, Miguel Blacutt, Vanina Dal Bello-Haas, Lori Quinn

Importance: Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease causing declines in muscular strength that affect respiratory function and functional independence. Although physical therapist interventions have been studied in ALS, their efficacy and evidence quality have not been systematically assessed across disease stages.

Objective: The objective of this study was to examine the efficacy of physical therapist interventions on clinical outcomes across ALS disease stages.

Design: This study was a systematic review using Joanna Briggs Institute methodology.

Setting: Multiple settings were used.

Participants: The participants were adults (>18 years old) with ALS or motor neuron disease.

Interventions: Physical therapist interventions within the professional scope of practice included therapeutic exercise, pulmonary training, manual therapy, and multimodal approaches.

Outcome measures: Outcome measures included effect sizes (ESs) and 95% CIs calculated for forced vital capacity (FVC) and the Amyotrophic Lateral Sclerosis Rating Scale (ALSFRS) or the ALSFRS revised (ALSFRS-R).

Results: Six databases were searched from inception to January 2025. Thirty-nine studies were included (25 experimental, 14 observational). Outcomes were heterogeneous, with 94 measures across studies: 23 included the ALSFRS or ALSFRS-R, and 16 included FVC. Most interventions targeted early-stage ALS (n = 27), limiting comparisons across stages. Multimodal training had moderate-quality evidence, with moderate effects on the ALSFRS-R (ES = 0.56 [95% CI = 0.09-1.03]), and low-quality evidence, with negligible effects on FVC (ES = -0.03 [95% CI = -1.47 to 1.41]). Pulmonary interventions had moderate-quality evidence, with small effects on FVC (ES = 0.40 [95% CI = -0.18 to 0.98]), and low-quality evidence, with negligible effects on the ALSFRS-R (ES = 0.04 [95% CI = -0.25 to 0.33]).

Conclusions: A range of physical therapist interventions for ALS were assessed, although most were early phase or low quality. Multimodal and pulmonary interventions showed modest benefits in the ALSFRS-R and FVC, respectively. However, variability in outcome measures and limited research beyond early-stage disease highlight the need for stage-specific trials using consistent functional outcomes.

Relevance: This review highlights the breadth of studies of physical therapy in ALS and underscores the need for more rigorous, targeted research.

重要性:肌萎缩性侧索硬化症(ALS)是一种进行性神经退行性疾病,引起肌肉力量下降,影响呼吸功能和功能独立性。虽然物理治疗师干预已经在ALS中进行了研究,但其疗效和证据质量尚未在疾病阶段进行系统评估。目的:本研究的目的是检查物理治疗师干预对ALS疾病分期临床结果的疗效。设计:本研究采用乔安娜布里格斯研究所的方法进行系统回顾。Setting:使用了多个设置。参与者:参与者为患有ALS或运动神经元疾病的成年人(bb0 - 18岁)。干预:物理治疗师在专业范围内的干预包括治疗性运动、肺训练、手工治疗和多模式方法。结果测量:结果测量包括用力肺活量(FVC)和肌萎缩侧索硬化症评定量表(ALSFRS)或经修订的ALSFRS- r计算的效应量(ESs)和95% ci。结果:检索了6个数据库,检索时间为建库至2025年1月。纳入39项研究(25项实验性研究,14项观察性研究)。结果是异质性的,共有94项研究测量:23项包括ALSFRS或ALSFRS- r, 16项包括FVC。大多数干预措施针对早期ALS (n = 27),限制了不同阶段的比较。多模式训练有中等质量的证据,对ALSFRS-R的影响中等(ES = 0.56 [95% CI = 0.09 ~ 1.03]),低质量的证据,对FVC的影响可以忽略不计(ES = -0.03 [95% CI = -1.47 ~ 1.41])。肺部干预有中等质量的证据,对FVC的影响较小(ES = 0.40 [95% CI = -0.18至0.98]),低质量的证据,对ALSFRS-R的影响可以忽略不计(ES = 0.04 [95% CI = -0.25至0.33])。结论:评估了一系列针对ALS的物理治疗师干预措施,尽管大多数是早期阶段或低质量的。多模式和肺部干预分别对ALSFRS-R和FVC有适度的益处。然而,结果测量的可变性和早期疾病以外的有限研究突出了使用一致功能结果的特定阶段试验的必要性。相关性:本综述强调了ALS物理治疗研究的广度,并强调了更严格、更有针对性的研究的必要性。
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引用次数: 0
Association Between Timing of Out-of-Bed Mobilization and Functional Outcomes at Intensive Care Unit Discharge in Patients With COVID-19: An Analysis of Potential Clinical Reference Points. COVID-19患者重症监护病房出院时床下活动时间与功能结局之间的关系:潜在临床参考点分析
IF 3.3 4区 医学 Q1 ORTHOPEDICS Pub Date : 2026-01-02 DOI: 10.1093/ptj/pzaf141
Debora Stripari Schujmann, Claudia Neri Peso, Adriana Claudia Lunardi, Jose Eduardo Pompeu, Leda Tomiko Yamada da Silveira, Raquel Annoni, Renato Fraga Righetti, Elaine Cristina de Campos, Wellington Pereira Yamaguti, Adriana Lourenço Pt, Sabrina Castaldi Aguera Pt, Mieko Claudia Miura, Cintia Claro Dos Santos Pt, Heloisa Francelin Pt, Clarice Tanaka, Carolina Fu

Importance: In patients who are critically ill, functional dependence and muscle weakness may be influenced by side effects related to the timing of out-of-bed mobilization, but there is a knowledge gap regarding the impact of exercise prescriptions in specific intensive care unit (ICU) populations.

Objective: The objective of this study was to determine clinical reference values for the time to start out-of-bed mobilization of patients in the ICU to avoid functional dependence and muscle weakness at ICU discharge.

Design: This study was a secondary analysis of a prospective multicenter cohort.

Setting: The settings were the ICUs of 5 Brazilian hospitals.

Participants: The participants were adult patients with COVID-19, an ICU stay of ≥4 days, and prior functional independence.

Exposure: Time for out-of-bed mobilization was the first day the patient was mobilized to higher postures, provided there were no contraindications.

Main outcomes and measures: Functional status (Barthel Index [BI]) and muscle strength (Medical Research Council Scale [MRC]) were assessed within 2 days of ICU discharge. Receiver operating characteristic analysis identified clinical thresholds for days to initiate out-of-bed mobilization in association with 2 levels of functional dependence and muscle weakness. Optimal cutoffs were based on sensitivity, specificity, and area under the curve (AUC).

Results: A total of 339 patients (58 years old [SD = 46-66 years old]; Simplified Acute Physiology Score III = 51.3 [SD = 16.5]; 36% women; 53% on mechanical ventilation) were analyzed. Days to start out-of-bed mobilization for each outcome were as follows: 3 days for a BI of <85 points (sensitivity = 67%, specificity = 65%, AUC = 0.68 [95% CI = 0.63-0.74]); 4 days for a BI of <60 points (sensitivity = 60%, specificity = 65%, AUC = 0.66 [95% CI = 0.59-0.73]); 5 days for an MRC score of <48 points (sensitivity = 54%, specificity = 73%, AUC = 0.66 [95% CI = 0.59-0.73]); and 5 days for an MRC score of <36 points (sensitivity = 69%, specificity = 67%, AUC = 0.67 [95% CI = 0.49-0.85]).

Conclusions: Early out-of-bed mobilization, initiated within 3 to 5 days of physiological readiness, may differentiate patients who develop functional dependence or ICU-acquired weakness at ICU discharge from those who do not. However, since discrimination ranged from 66% to 68%, with a narrow margin for worse outcomes, this recommendation should be interpreted within context.

Relevance: Knowing clinical reference points for days to initiate out-of-bed exercises may help minimize poor physical outcomes at ICU discharge.

重要性:在危重患者中,功能依赖和肌肉无力可能受到与床下活动时间相关的副作用的影响,但在特定的重症监护病房(ICU)人群中,关于运动处方的影响存在知识差距。目的:本研究的目的是确定ICU患者开始下床活动的时间的临床参考值,以避免ICU出院时的功能依赖和肌肉无力。设计:本研究是一项前瞻性多中心队列的二次分析。设置:设置为巴西5家医院的icu。参与者:参与者为成年COVID-19患者,ICU住院≥4天,既往功能独立。暴露:在无禁忌症的情况下,床下活动时间为患者活动至较高体位的第一天。主要观察指标:功能状态(Barthel指数[BI])和肌力(医学研究委员会量表[MRC])在ICU出院后2天内进行评估。患者操作特征分析确定了与2级功能依赖和肌肉无力相关的开始下床活动的临床阈值。最佳截止值基于灵敏度、特异性和曲线下面积(AUC)。结果:共分析339例患者(年龄58岁[SD = 46 ~ 66岁];简化急性生理评分III = 51.3 [SD = 16.5];女性36%;机械通气53%)。每个结果开始下床活动的天数如下:BI的3天结论:在生理准备就绪的3至5天内开始的早期下床活动可以区分在ICU出院时出现功能依赖或ICU获得性虚弱的患者。然而,由于歧视范围从66%到68%不等,结果较差的差距很小,因此应在上下文中解释这一建议。相关性:了解临床参考点数天开始床下锻炼可能有助于减少ICU出院时不良的身体结果。
{"title":"Association Between Timing of Out-of-Bed Mobilization and Functional Outcomes at Intensive Care Unit Discharge in Patients With COVID-19: An Analysis of Potential Clinical Reference Points.","authors":"Debora Stripari Schujmann, Claudia Neri Peso, Adriana Claudia Lunardi, Jose Eduardo Pompeu, Leda Tomiko Yamada da Silveira, Raquel Annoni, Renato Fraga Righetti, Elaine Cristina de Campos, Wellington Pereira Yamaguti, Adriana Lourenço Pt, Sabrina Castaldi Aguera Pt, Mieko Claudia Miura, Cintia Claro Dos Santos Pt, Heloisa Francelin Pt, Clarice Tanaka, Carolina Fu","doi":"10.1093/ptj/pzaf141","DOIUrl":"10.1093/ptj/pzaf141","url":null,"abstract":"<p><strong>Importance: </strong>In patients who are critically ill, functional dependence and muscle weakness may be influenced by side effects related to the timing of out-of-bed mobilization, but there is a knowledge gap regarding the impact of exercise prescriptions in specific intensive care unit (ICU) populations.</p><p><strong>Objective: </strong>The objective of this study was to determine clinical reference values for the time to start out-of-bed mobilization of patients in the ICU to avoid functional dependence and muscle weakness at ICU discharge.</p><p><strong>Design: </strong>This study was a secondary analysis of a prospective multicenter cohort.</p><p><strong>Setting: </strong>The settings were the ICUs of 5 Brazilian hospitals.</p><p><strong>Participants: </strong>The participants were adult patients with COVID-19, an ICU stay of ≥4 days, and prior functional independence.</p><p><strong>Exposure: </strong>Time for out-of-bed mobilization was the first day the patient was mobilized to higher postures, provided there were no contraindications.</p><p><strong>Main outcomes and measures: </strong>Functional status (Barthel Index [BI]) and muscle strength (Medical Research Council Scale [MRC]) were assessed within 2 days of ICU discharge. Receiver operating characteristic analysis identified clinical thresholds for days to initiate out-of-bed mobilization in association with 2 levels of functional dependence and muscle weakness. Optimal cutoffs were based on sensitivity, specificity, and area under the curve (AUC).</p><p><strong>Results: </strong>A total of 339 patients (58 years old [SD = 46-66 years old]; Simplified Acute Physiology Score III = 51.3 [SD = 16.5]; 36% women; 53% on mechanical ventilation) were analyzed. Days to start out-of-bed mobilization for each outcome were as follows: 3 days for a BI of <85 points (sensitivity = 67%, specificity = 65%, AUC = 0.68 [95% CI = 0.63-0.74]); 4 days for a BI of <60 points (sensitivity = 60%, specificity = 65%, AUC = 0.66 [95% CI = 0.59-0.73]); 5 days for an MRC score of <48 points (sensitivity = 54%, specificity = 73%, AUC = 0.66 [95% CI = 0.59-0.73]); and 5 days for an MRC score of <36 points (sensitivity = 69%, specificity = 67%, AUC = 0.67 [95% CI = 0.49-0.85]).</p><p><strong>Conclusions: </strong>Early out-of-bed mobilization, initiated within 3 to 5 days of physiological readiness, may differentiate patients who develop functional dependence or ICU-acquired weakness at ICU discharge from those who do not. However, since discrimination ranged from 66% to 68%, with a narrow margin for worse outcomes, this recommendation should be interpreted within context.</p><p><strong>Relevance: </strong>Knowing clinical reference points for days to initiate out-of-bed exercises may help minimize poor physical outcomes at ICU discharge.</p>","PeriodicalId":20093,"journal":{"name":"Physical Therapy","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145648778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Letter by Altenburger, Jette, Kosior, Pak, and Topp on "Are There Speed Limits in Doctor of Physical Therapy Education? Future Research Directions." Davis SD. Phys Ther. 2025;105:pzaf079. https://doi.org/10.1093/ptj/pzaf079. Jette, Altenburger, Kosior, Pak和Topp关于“物理治疗教育博士有速度限制吗?”未来研究方向。”戴维斯SD。物理学报。2025;105:pzaf079。10.1093 / ptj / pzaf079。
IF 3.3 4区 医学 Q1 ORTHOPEDICS Pub Date : 2026-01-02 DOI: 10.1093/ptj/pzaf146
Peter Altenburger, Diane U Jette, Ken Kosior, Sang Pak, Kimberly Topp
{"title":"Letter by Altenburger, Jette, Kosior, Pak, and Topp on \"Are There Speed Limits in Doctor of Physical Therapy Education? Future Research Directions.\" Davis SD. Phys Ther. 2025;105:pzaf079. https://doi.org/10.1093/ptj/pzaf079.","authors":"Peter Altenburger, Diane U Jette, Ken Kosior, Sang Pak, Kimberly Topp","doi":"10.1093/ptj/pzaf146","DOIUrl":"10.1093/ptj/pzaf146","url":null,"abstract":"","PeriodicalId":20093,"journal":{"name":"Physical Therapy","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145757321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
My View of PTJ: Updates From the Home Office. 我对PTJ的看法:来自内政部的更新。
IF 3.3 4区 医学 Q1 ORTHOPEDICS Pub Date : 2026-01-02 DOI: 10.1093/ptj/pzaf155
Steven Z George
{"title":"My View of PTJ: Updates From the Home Office.","authors":"Steven Z George","doi":"10.1093/ptj/pzaf155","DOIUrl":"https://doi.org/10.1093/ptj/pzaf155","url":null,"abstract":"","PeriodicalId":20093,"journal":{"name":"Physical Therapy","volume":"106 1","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146066018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Physical Therapy
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