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Serendipity How? Data Insights During the Age of Artificial Intelligence. 意外如何?人工智能时代的数据洞察。
IF 3.3 4区 医学 Q1 ORTHOPEDICS Pub Date : 2025-11-03 DOI: 10.1093/ptj/pzaf128
Steven Z George
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引用次数: 0
Educating for Impact: The Imperative of Health Systems Science in Physical Therapy. 教育的影响:卫生系统科学在物理治疗的必要性。
IF 3.3 4区 医学 Q1 ORTHOPEDICS Pub Date : 2025-11-03 DOI: 10.1093/ptj/pzaf125
Gregory W Hartley, Gail Jensen, Neva Kirk-Sanchez, Merrill R Landers, Susan Skochelak

While health systems science (HSS) is now recognized as a foundational pillar in medical education, the profession of physical therapy has yet to fully integrate this unifying framework into its educational models. Health systems science offers a structured lens through which the profession can align its long-standing values such as patient-centered care, equity, and interprofessional collaboration, with the demands of a health care system that is complex, fragmented, and driven by accountability, data, and value. Without explicit incorporation of HSS into Doctor of Physical Therapy (DPT) curricula, the profession may have a diminished voice in critical conversations around health care equity, health system innovation, policy reform, and care redesign. This perspective presents an example from the University of Miami's DPT program, where HSS was systematically embedded across the curriculum using Kern's 6-step model for curriculum development. The process included comprehensive content mapping and intentional faculty development to promote a shared understanding of systems thinking and its relevance to physical therapist practice. As a result, DPT students are now engaged in learning that situates their clinical decision making within the broader structures, policies, and processes that shape patient outcomes at both individual and population levels. Health systems science enables physical therapists to move beyond implicit alignment with health system goals to active participation in advancing them. A physical therapist educated in HSS is positioned to contribute to population health by designing community-based interventions, participating in cross-sector partnerships, addressing social determinants of health, and applying data to reduce disparities in function and access. The framework also supports engagement in value-based care delivery, quality improvement initiatives, health informatics, and health policy development; areas central to the sustainability and evolution of health care. To remain relevant and impactful, this perspective offers a call to action for physical therapist educators to integrate HSS as a core component of professional formation and practice readiness.

虽然卫生系统科学(HSS)现在被认为是医学教育的基础支柱,但物理治疗专业尚未将这一统一框架完全整合到其教育模式中。HSS提供了一个结构化的视角,通过这个视角,医疗行业可以将其长期存在的价值观(如以患者为中心的护理、公平和跨专业合作)与复杂、分散、由责任、数据和价值驱动的医疗保健系统的需求结合起来。如果没有明确将HSS纳入物理治疗博士(DPT)课程,该专业在围绕医疗保健公平、卫生系统创新、政策改革和护理重新设计的关键对话中的发言权可能会减弱。这个视角展示了迈阿密大学DPT项目的一个例子,在该项目中,HSS系统地嵌入到课程中,使用Kern的课程开发六步模型。这个过程包括全面的内容映射和有意的教师发展,以促进对系统思维及其与物理治疗师实践的相关性的共同理解。因此,DPT学生现在正在学习将他们的临床决策置于更广泛的结构、政策和过程中,这些结构、政策和过程在个人和群体层面上塑造了患者的结果。HSS使物理治疗师能够超越与卫生系统目标的隐性一致,积极参与推进这些目标。受过HSS教育的物理治疗师可以通过设计基于社区的干预措施、参与跨部门伙伴关系、解决健康的社会决定因素以及应用数据来减少功能和获取方面的差异,从而为人口健康做出贡献。该框架还支持参与基于价值的保健服务、质量改进举措、卫生信息学和卫生政策制定;对保健的可持续性和发展至关重要的领域。为了保持相关性和影响力,这一观点呼吁物理治疗师教育工作者将HSS作为专业形成和实践准备的核心组成部分。
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引用次数: 0
Does Treating Low Back Pain With Therapeutic Exercise Reduce the Risk of Subsequent Lower Extremity Injury? A Population-Level Cohort Analysis. 用治疗性运动治疗腰痛能降低随后下肢损伤的风险吗?人口水平的队列分析。
IF 3.3 4区 医学 Q1 ORTHOPEDICS Pub Date : 2025-11-03 DOI: 10.1093/ptj/pzaf122
Kaitlyn Foster, Sharon Wang-Price, Mark Weber, Kelli Brizzolara, Xiaoning Yuan, Riley Boeth, Daniel I Rhon

Importance: The trunk and lower extremities are the most common locations for injury in the military, but they are managed as isolated regions. This study suggests these regions are connected, and utilization of therapeutic exercise is protective of lower extremity injury following low-back-pain diagnosis.

Objective: The objective of this study was to determine whether therapeutic exercise for low back pain reduces risk of subsequent lower extremity injury.

Design: This study utilized a longitudinal cohort design based on routinely collected health information.

Setting: This study was conducted within the Military Health System.

Participants: Patients aged 18 to 65 who sought care for low back pain between January 2015 and July 2019 were identified using diagnosis codes from electronic medical records and claims data.

Interventions: Participants were dichotomized based on whether they received therapeutic exercise.

Main outcomes and measures: Cox proportional hazards regression with hazard ratios (HRs) was used to model the relationship between therapeutic exercise use and dosing and risk of subsequent hip, knee, and ankle injury.

Results: Out of 452,668 patients (34.8% female; age 35.5 [12.3] years), 74,912 (16.5%) received at least 1 therapeutic exercise session, with a median (IQR) of 3 (1-6) sessions. Therapeutic exercise receipt significantly decreased subsequent lower extremity injury risk (hip: HR = 0.84, 95% CI = 0.825-0.852; knee: HR = 0.77, 95% CI = 0.756-0.777; and ankle/foot: HR = 0.80, 95% CI = 0.788-0.809), and that risk decreased further with each additional exercise session (hip: HR = 0.95, 95% CI = 0.942-0.948; knee: HR = 0.96, 95% CI = 0.956-0.963; and ankle/foot: HR = 0.96, 95% CI = 0.961-0.967).

Conclusions: Patients with low back pain not treated with therapeutic exercise had an increased risk of subsequent lower extremity injury. For those who received therapeutic exercise, the risk for subsequent injury was reduced with additional sessions.

Relevance: Treating low-back-pain patients with therapeutic exercise may decrease the health-care burden.

重要性:躯干和下肢是军队中最常见的受伤部位,但被当作孤立的区域来管理。这项研究表明,这些区域是相互联系的,治疗性运动的利用对诊断为腰痛的下肢损伤具有保护作用。目的:本研究的目的是确定治疗性运动对腰痛是否能降低随后下肢损伤的风险。设计:本研究采用基于常规收集的健康信息的纵向队列设计。背景:本研究在军队卫生系统内进行。参与者:使用电子病历和索赔数据中的诊断代码确定2015年1月至2019年7月期间因腰痛寻求治疗的18至65岁患者。干预措施:参与者根据他们是否接受治疗性运动被分为两类。主要结局和测量方法:采用Cox比例风险回归模型对治疗性运动使用和剂量对随后髋关节、膝关节和踝关节损伤风险的关系进行风险比建模。结果:在452,668例患者中(34.8%为女性,年龄35.5[12.3]岁),74,912例(16.5%)患者接受了至少1次治疗性运动,中位(IQR)为3(1-6)次。治疗性运动接受显著降低了随后下肢损伤的风险(髋部:HR = 0.84, 95% CI = 0.825-0.852;膝关节:HR = 0.77, 95% CI = 0.756-0.777;踝关节/足:HR = 0.80, 95% CI = 0.788-0.809),并且随着每增加一次运动,风险进一步降低(髋部:HR = 0.95, 95% CI = 0.942-0.948;膝关节:HR = 0.96, 95% CI = 0.956-0.963;踝关节/足:HR = 0.96, 95% CI = 0.961-0.967)。结论:未接受治疗性运动治疗的腰痛患者随后下肢损伤的风险增加。对于那些接受治疗性锻炼的人,后续受伤的风险随着额外的锻炼而降低。相关性:治疗性运动治疗腰痛患者可减轻保健负担。
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引用次数: 0
Competency-Based Education: Development of the Entry-Level Pain Entrustable Professional Activities for Workplace-Based Assessment. 能力本位教育:基于工作场所评估的入门级疼痛可信赖专业活动的发展。
IF 3.3 4区 医学 Q1 ORTHOPEDICS Pub Date : 2025-11-03 DOI: 10.1093/ptj/pzaf126
Jeb Helms, Kory Zimney, Priscilla Weaver, Carol Courtney, Craig Wassinger

Importance: The physical therapy profession is being called to adopt a competency-based education (CBE) model, following the lead of other health professions. A key element of CBE is workplace-based assessment, in which clinicians evaluate learners' readiness to perform essential clinical tasks through entrustable professional activities (EPAs). Although a common set of EPAs exist for the profession, none currently guide assessment and learning in specialty areas like pain.

Objective: The objective of this study was to describe the development and initial validation of pain-specific entrustable professional activities (Pain EPAs) designed to assess physical therapist clinical competency in managing pain within a CBE framework.

Design: This was a developmental study following published recommendations for EPA creation, including preparation, drafting, quality control, and curriculum alignment.

Setting: The study was conducted across 4 American universities.

Participants: Five American-based physical therapists collaborated on EPA development and gathered feedback from educators, clinicians, and an 8-person reactor panel.

Intervention: The intervention involved developing Pain EPAs through expert consensus and external review for alignment with competency frameworks.

Main outcome: The main outcome was a set of Pain EPAs reviewed for clarity, observability, and assessability using the EQual rubric, with external feedback guiding their categorization.

Results: Twenty-one Pain EPAs were developed and aligned with pain competency frameworks, with feedback organizing them into 4 levels of increasing complexity and autonomy: generalist, pain-specific entry-level, specialty clinic entry-level, and advanced practice.

Conclusions: This study outlines a structured, replicable approach for developing EPAs aligned with CBE principles. The Pain EPAs provide an initial framework to assess readiness for autonomous pain management tasks. Further research is needed to establish their validity and support implementation in entry-level and post-professional training.

Relevance: The Pain EPAs support CBE workplace-based assessment in physical therapist education. This approach can be adapted for other specialty areas within physical therapist practice.

重要性:物理治疗专业正在被呼吁采用能力为基础的教育(CBE)模式,跟随其他卫生专业的领导。CBE的一个关键要素是基于工作场所的评估,其中临床医生通过可信赖的专业活动(EPAs)评估学习者执行基本临床任务的准备情况。虽然有一套通用的专业EPAs,但目前还没有一个指导像疼痛这样的专业领域的评估和学习。目的:本研究的目的是描述疼痛特异性可信赖专业活动(Pain EPAs)的发展和初步验证,旨在评估物理治疗师在CBE框架内管理疼痛的临床能力。设计:这是一项发展性研究,遵循已发表的EPA创建建议,包括准备、起草、质量控制和课程调整。环境:该研究在美国四所大学进行。参与者:五名美国物理治疗师合作开发EPA,并从教育工作者、临床医生和一个8人反应堆小组收集反馈。干预:干预包括通过专家共识和外部审查来制定Pain EPAs,以与能力框架保持一致。主要结果:主要结果是一组疼痛EPAs的清晰度、可观察性和可评估性,使用EQual标题进行审查,并使用外部反馈指导其分类。结果:21个疼痛EPAs被开发并与疼痛能力框架保持一致,反馈将它们分为4个层次,越来越复杂和自主:通才,疼痛特异性入门级,专科临床入门级和高级实践。结论:本研究概述了一种结构化的、可复制的方法,用于开发符合CBE原则的epa。疼痛EPAs提供了一个初步框架来评估自主疼痛管理任务的准备情况。需要进一步研究以确定其有效性并支持在入门级和专业后培训中实施。相关性:疼痛EPAs支持物理治疗师教育中基于CBE工作场所的评估。这种方法可以适用于物理治疗师实践中的其他专业领域。
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引用次数: 0
Adverse Events in the MASH Randomized Controlled Trial With Detailed Reporting of Musculoskeletal and Connective Tissue Disorders Events. 详细报告肌肉骨骼和结缔组织疾病事件的MASH随机对照试验中的不良事件。
IF 3.3 4区 医学 Q1 ORTHOPEDICS Pub Date : 2025-11-03 DOI: 10.1093/ptj/pzaf124
Jaclyn M Sions, Steven Z George, Jenifer M Pugliese, Charity G Patterson, Sara Piva, Corey B Simon, Gregory E Hicks

Importance: Older adults and those with low back pain (LBP) are at increased risk of research-related adverse events (AEs); yet, Cochrane reviews show AE under-reporting in rehabilitation trials.

Objective: To inform AE practices in future rehabilitation trials, details are provided on novel AE surveillance and reporting practices used in the Manual Therapy and Strengthening for the Hip (MASH) trial.

Design: The study design was a secondary analysis of a multisite, single-masked, randomized controlled trial comparing 2 exercise-inclusive interventions.

Setting: The study was conducted at research-based physical therapist sites.

Participants: Participants were older adults with moderate-intensity, chronic LBP with hip pain and muscle weakness.

Interventions or exposures: Participants were randomly assigned to receive 16 sessions of hip-focused or spine-focused physical therapy over 8 weeks. Active AE monitoring was facilitated with standardized interviews during each treatment session and at 8-week, 3-, 4-, 5-, and 6-months. Common terminology criteria for AEs classification was used. AEs were adjudicated by a site investigator and reviewed at multisite meetings.

Main outcomes and measures: AE classification, relatedness, expectedness, severity, timing, recurrence, duration, and intervention impact were evaluated between interventions.

Results: Among 184 participants, there were 243 AEs (n = 128 hip-focused group, n = 115 spine-focused group) in 112 participants; 38.3% were unexpected, with 47 occurring in the hip-focused and 46 in the spine-focused group. AE relatedness, expectedness, and severity were similar between groups. Of the 243 AEs, 157 were mild, 71 were moderate, and 15 were severe/life threatening. Most AEs (80.2%) occurred early and were classified as musculoskeletal and connective tissue disorders (MSKCT), with shorter MSKCT AE duration in the hip-focused group. Within each group, 15 MSKCT AEs resulted in study modification.

Conclusions and relevance: This analysis describes a framework to improve upon active AE surveillance during rehabilitation trials to better inform risk-to-benefit analyses. Data can also be used to inform clinical decision-making related to risks from MASH trial interventions.

重要性:老年人和腰痛患者发生研究相关不良事件(AE)的风险增加,但Cochrane综述显示康复试验中AE的报道不足。目的:为了在未来的康复试验中为声发射实践提供信息,详细介绍了在髋部手工治疗和强化(MASH)试验中使用的新型声发射监测和报告实践。设计:研究设计是一项多地点、单掩蔽、随机对照试验的二次分析,比较两种包括运动的干预措施。环境:本研究在研究型物理治疗师场所进行。参与者:参与者是患有中等强度、慢性腰痛、髋关节痛和肌肉无力的老年人。干预或暴露:参与者被随机分配在8周内接受16次以髋部或脊柱为重点的物理治疗。在每次治疗期间以及8周、3个月、4个月、5个月和6个月时,通过标准化访谈进行主动AE监测。使用通用术语标准进行ae分类。ae由现场调查员裁决,并在多地点会议上进行审查。主要结局和测量指标:评估AE的分类、相关性、预期性、严重程度、时间、复发、持续时间和干预效果。结果:184名受试者中,112名受试者中有243例ae(髋部为重点组128例,脊柱为重点组115例);38.3%是意料之外的,其中47例发生在髋关节集中组,46例发生在脊柱集中组。AE相关性、预期性和严重程度在两组间相似。243例ae中,157例为轻度,71例为中度,15例为严重/危及生命。大多数AE(80.2%)发生早期,并被归类为肌肉骨骼和结缔组织疾病(MSKCT),以髋关节为重点的组的MSKCT AE持续时间较短。在每组中,15例MSKCT ae导致研究修改。结论和相关性:本分析描述了一个框架,以改进康复试验期间的主动AE监测,从而更好地为风险-收益分析提供信息。数据也可用于告知与MASH试验干预风险相关的临床决策。
{"title":"Adverse Events in the MASH Randomized Controlled Trial With Detailed Reporting of Musculoskeletal and Connective Tissue Disorders Events.","authors":"Jaclyn M Sions, Steven Z George, Jenifer M Pugliese, Charity G Patterson, Sara Piva, Corey B Simon, Gregory E Hicks","doi":"10.1093/ptj/pzaf124","DOIUrl":"10.1093/ptj/pzaf124","url":null,"abstract":"<p><strong>Importance: </strong>Older adults and those with low back pain (LBP) are at increased risk of research-related adverse events (AEs); yet, Cochrane reviews show AE under-reporting in rehabilitation trials.</p><p><strong>Objective: </strong>To inform AE practices in future rehabilitation trials, details are provided on novel AE surveillance and reporting practices used in the Manual Therapy and Strengthening for the Hip (MASH) trial.</p><p><strong>Design: </strong>The study design was a secondary analysis of a multisite, single-masked, randomized controlled trial comparing 2 exercise-inclusive interventions.</p><p><strong>Setting: </strong>The study was conducted at research-based physical therapist sites.</p><p><strong>Participants: </strong>Participants were older adults with moderate-intensity, chronic LBP with hip pain and muscle weakness.</p><p><strong>Interventions or exposures: </strong>Participants were randomly assigned to receive 16 sessions of hip-focused or spine-focused physical therapy over 8 weeks. Active AE monitoring was facilitated with standardized interviews during each treatment session and at 8-week, 3-, 4-, 5-, and 6-months. Common terminology criteria for AEs classification was used. AEs were adjudicated by a site investigator and reviewed at multisite meetings.</p><p><strong>Main outcomes and measures: </strong>AE classification, relatedness, expectedness, severity, timing, recurrence, duration, and intervention impact were evaluated between interventions.</p><p><strong>Results: </strong>Among 184 participants, there were 243 AEs (n = 128 hip-focused group, n = 115 spine-focused group) in 112 participants; 38.3% were unexpected, with 47 occurring in the hip-focused and 46 in the spine-focused group. AE relatedness, expectedness, and severity were similar between groups. Of the 243 AEs, 157 were mild, 71 were moderate, and 15 were severe/life threatening. Most AEs (80.2%) occurred early and were classified as musculoskeletal and connective tissue disorders (MSKCT), with shorter MSKCT AE duration in the hip-focused group. Within each group, 15 MSKCT AEs resulted in study modification.</p><p><strong>Conclusions and relevance: </strong>This analysis describes a framework to improve upon active AE surveillance during rehabilitation trials to better inform risk-to-benefit analyses. Data can also be used to inform clinical decision-making related to risks from MASH trial interventions.</p>","PeriodicalId":20093,"journal":{"name":"Physical Therapy","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12666779/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145281011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Depressive Symptoms and Physical Activity Mediate the Adverse Effect of Pain on Functional Dependence in Patients With Arthritis: Evidence From the Canadian Longitudinal Study on Aging. 抑郁症状和体力活动介导疼痛对关节炎患者功能依赖的不良影响:来自加拿大衰老纵向研究的证据
IF 3.3 4区 医学 Q1 ORTHOPEDICS Pub Date : 2025-11-03 DOI: 10.1093/ptj/pzaf120
Miriam Goubran, Zachary M van Allen, Martin Bilodeau, Matthieu P Boisgontier

Importance: Arthritis is a chronic condition affecting hundreds of millions of people worldwide, often leading to pain and functional limitations.

Objective: This study aimed to investigate the direct and indirect effects of pain on functional dependence in individuals with arthritis. Depressive symptoms and physical activity were examined as potential mediators of this relationship.

Design: This study was a longitudinal cohort study.

Setting: The study setting included community-dwelling adults participating in the Canadian Longitudinal Study on Aging.

Participants: This study sample consisted of 6972 participants with arthritis, including 4930 with osteoarthritis and 694 with rheumatoid arthritis.

Exposure: The exposure was the usual presence of pain or discomfort at baseline, with depressive symptoms (CESD-10) and physical activity (PASE) tested as mediators.

Main outcome and measure: The main outcome was functional dependence in basic activities of daily living (ADL) and instrumental activities of daily living (IADL) at follow-up, measured with a modified version of the Older Americans' Resources and Services Multidimensional Functional Assessment Questionnaire (OARS).

Results: Baseline pain was positively associated with depressive symptoms (b = 0.356 [95% CI = 0.310 to 0.402]) and negatively associated with physical activity (b = -0.083 [95% CI = -0.125 to -0.042]). Functional dependence at follow-up was significantly predicted by baseline pain (log OR = 0.607 [95% CI = 0.261 to 0.952]), depressive symptoms (log OR = 0.358 [95% CI = 0.184 to 0.533]), and physical activity (log OR = -0.598 [95% CI = -0.818 to -0.378]). Mediation analysis showed that 23.3% of the total effect of pain on functional dependence was accounted for by the indirect effect through depressive symptoms (16.2%), physical activity (6.3%), and their serial combination (0.8%).

Conclusions: The presence of pain at baseline was associated with higher odds of functional dependence in basic and instrumental activities of daily living after a mean follow-up period of 6.3 years, with depressive symptoms and lower physical activity acting as mediators.

Relevance: The findings highlight the need for arthritis care to extend beyond pain management by incorporating strategies that address depressive symptoms and promote physical activity to preserve functional independence.

重要性:关节炎是一种影响全球数亿人的慢性疾病,通常会导致疼痛和功能限制。目的:本研究旨在探讨疼痛对关节炎患者功能依赖的直接和间接影响。抑郁症状和身体活动被认为是这种关系的潜在中介。设计:本研究为纵向队列研究。研究环境:研究环境包括参加加拿大老龄化纵向研究的社区居住成年人。参与者:这项研究共包括6972名关节炎患者,其中4930名患有骨关节炎,694名患有类风湿关节炎。暴露:暴露通常是基线时疼痛或不适的存在,抑郁症状(CESD-10)和身体活动(PASE)作为介质进行测试。主要结果和测量:主要结果是日常生活活动(ADL)和日常生活工具活动(IADL)的功能依赖,使用修改版的美国老年人资源和服务多维功能评估问卷(OARS)进行测量。结果:基线疼痛与抑郁症状呈正相关(b = 0.356 [95% CI = 0.310 ~ 0.402]),与身体活动呈负相关(b = -0.083 [95% CI = -0.125 ~ -0.042])。基线疼痛(log OR = 0.607 [95% CI = 0.261至0.952])、抑郁症状(log OR = 0.358 [95% CI = 0.184至0.533])和身体活动(log OR = -0.598 [95% CI = -0.818至-0.378])显著预测了随访时的功能依赖。中介分析显示,疼痛对功能依赖的总影响中,有23.3%是通过抑郁症状(16.2%)、体力活动(6.3%)及其系列组合(0.8%)产生的间接影响。结论:在平均6.3年的随访期后,基线时疼痛的存在与日常生活中基本和工具活动的功能依赖的较高几率相关,抑郁症状和较低的体力活动是中介。相关性:研究结果强调了关节炎护理需要扩展到疼痛管理之外,通过结合解决抑郁症状和促进身体活动以保持功能独立性的策略。
{"title":"Depressive Symptoms and Physical Activity Mediate the Adverse Effect of Pain on Functional Dependence in Patients With Arthritis: Evidence From the Canadian Longitudinal Study on Aging.","authors":"Miriam Goubran, Zachary M van Allen, Martin Bilodeau, Matthieu P Boisgontier","doi":"10.1093/ptj/pzaf120","DOIUrl":"10.1093/ptj/pzaf120","url":null,"abstract":"<p><strong>Importance: </strong>Arthritis is a chronic condition affecting hundreds of millions of people worldwide, often leading to pain and functional limitations.</p><p><strong>Objective: </strong>This study aimed to investigate the direct and indirect effects of pain on functional dependence in individuals with arthritis. Depressive symptoms and physical activity were examined as potential mediators of this relationship.</p><p><strong>Design: </strong>This study was a longitudinal cohort study.</p><p><strong>Setting: </strong>The study setting included community-dwelling adults participating in the Canadian Longitudinal Study on Aging.</p><p><strong>Participants: </strong>This study sample consisted of 6972 participants with arthritis, including 4930 with osteoarthritis and 694 with rheumatoid arthritis.</p><p><strong>Exposure: </strong>The exposure was the usual presence of pain or discomfort at baseline, with depressive symptoms (CESD-10) and physical activity (PASE) tested as mediators.</p><p><strong>Main outcome and measure: </strong>The main outcome was functional dependence in basic activities of daily living (ADL) and instrumental activities of daily living (IADL) at follow-up, measured with a modified version of the Older Americans' Resources and Services Multidimensional Functional Assessment Questionnaire (OARS).</p><p><strong>Results: </strong>Baseline pain was positively associated with depressive symptoms (b = 0.356 [95% CI = 0.310 to 0.402]) and negatively associated with physical activity (b = -0.083 [95% CI = -0.125 to -0.042]). Functional dependence at follow-up was significantly predicted by baseline pain (log OR = 0.607 [95% CI = 0.261 to 0.952]), depressive symptoms (log OR = 0.358 [95% CI = 0.184 to 0.533]), and physical activity (log OR = -0.598 [95% CI = -0.818 to -0.378]). Mediation analysis showed that 23.3% of the total effect of pain on functional dependence was accounted for by the indirect effect through depressive symptoms (16.2%), physical activity (6.3%), and their serial combination (0.8%).</p><p><strong>Conclusions: </strong>The presence of pain at baseline was associated with higher odds of functional dependence in basic and instrumental activities of daily living after a mean follow-up period of 6.3 years, with depressive symptoms and lower physical activity acting as mediators.</p><p><strong>Relevance: </strong>The findings highlight the need for arthritis care to extend beyond pain management by incorporating strategies that address depressive symptoms and promote physical activity to preserve functional independence.</p>","PeriodicalId":20093,"journal":{"name":"Physical Therapy","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12613829/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145213312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cost-Effectiveness of Physical Therapist Treatment in Addition to Usual Podiatry Management of Plantar Heel Pain: Economic Evaluation of a Randomized Clinical Trial. 除常规足部治疗外,物理治疗师治疗足底跟痛的成本效益:一项随机临床试验的经济评估。
IF 3.3 4区 医学 Q1 ORTHOPEDICS Pub Date : 2025-11-03 DOI: 10.1093/ptj/pzaf119
Shane M McClinton, Bryan C Heiderscheit, Timothy W Flynn, Daniel Pinto

Importance: Plantar heel pain (PHP) contributes to reduced quality of life and is costly to manage. Persons with PHP are infrequently referred to a physical therapist after presenting to primary care or podiatry.

Objective: The study objective was to compare the cost-effectiveness of usual podiatry care (uPOD) plus physical therapist treatment with that of uPOD alone in the management of PHP.

Design: A cost-effectiveness analysis from societal and health care sector perspectives and a 3-year time horizon was performed alongside a randomized clinical trial. Intention to treat was used as the base case, and sensitivity analyses were used to assess the impact of adherence to treatment (ie, per protocol) and PHP-specific costs.

Setting: The setting was a multidisciplinary outpatient clinic in the United States.

Participants: Participants were 95 eligible patients with PHP.

Interventions: uPOD consisted of a stretching handout, medication, injections, and orthotics; uPOD plus physical therapist treatment also included physical therapist intervention consisting of manual therapy, exercise, foot taping, and iontophoresis.

Main outcomes and measures: Cost-effectiveness was determined by between-group differences in costs relative to quality-adjusted life-years (QALYs). Cost-effectiveness at different thresholds of decision maker willingness to pay was illustrated using the cost-effectiveness acceptability curve.

Results: uPOD plus physical therapist treatment reduced societal costs by $2708 (95% CI = -$294 to $5709) relative to uPOD and increased QALYs by 0.09 (95% CI = -0.01 to 0.18). The cost-effectiveness acceptability curve demonstrated 98%, 99%, and 97% probabilities of cost-effectiveness of uPOD plus physical therapist treatment in the base-case, per-protocol, and PHP-specific cost analyses using a willingness-to-pay threshold of $50,000 per QALY.

Conclusions: Adding physical therapist treatment to uPOD lowered total costs and improved quality of life despite increased short-term health care utilization. Results were not altered when considering adherence to treatment or PHP-specific costs.

Relevance: This study informs shared decision-making between providers and patients with PHP about the costs and benefits of adding physical therapist treatment and provides support for the economic value of physical therapist treatment for PHP.

重要性:足底跟痛(PHP)会降低生活质量,而且治疗成本高。PHP患者在初级保健或足部就诊后很少被转介给物理治疗师。目的:研究目的是比较常规足部护理(uPOD)加物理治疗师治疗与单独uPOD治疗在PHP治疗中的成本-效果。设计:从社会和卫生保健部门的角度和3年的时间范围进行成本效益分析,并进行随机临床试验。治疗意向作为基本案例,使用敏感性分析来评估治疗依从性(即每个方案)和php特定成本的影响。研究背景:研究背景是美国一家多学科门诊诊所。参与者:参与者为95例符合条件的PHP患者。干预措施:uPOD包括伸展讲义、药物、注射和矫形器;uPOD加物理治疗师治疗还包括物理治疗师干预,包括手工治疗、运动、足部贴敷和离子导入。主要结局和测量方法:成本-效果由相对于质量调整生命年(QALYs)的组间成本差异决定。用成本效益可接受度曲线说明了决策者在不同支付意愿阈值下的成本效益。结果:与uPOD相比,uPOD加物理治疗师治疗减少了2708美元的社会成本(95% CI = - 294美元至5709美元),qaly增加了0.09美元(95% CI = -0.01至0.18)。成本-效果可接受度曲线显示,在基础案例、每个方案和php特定成本分析中,uPOD加物理治疗师治疗的成本-效果概率分别为98%、99%和97%,每个QALY的支付意愿阈值为50,000美元。结论:在uPOD中加入物理治疗师治疗降低了总成本,改善了生活质量,尽管短期医疗保健使用率增加。当考虑治疗依从性或php特异性费用时,结果没有改变。相关性:本研究为PHP提供者和患者之间关于增加物理治疗师治疗的成本和收益的共同决策提供了信息,并为PHP物理治疗师治疗的经济价值提供了支持。
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引用次数: 0
Effect of Telerehabilitation in Parkinson Disease: A Systematic Review and Meta-Analysis. 远程康复对帕金森病的影响:一项系统综述和meta分析。
IF 3.3 4区 医学 Q1 ORTHOPEDICS Pub Date : 2025-11-03 DOI: 10.1093/ptj/pzaf121
Paria Darbandsari, Linda S Pescatello, Daniele Piscitelli, James M Smith, Alessandro Ugolini, Cristina Colón-Semenza

Importance: Rehabilitation is a key in managing Parkinson disease (PD), but access barriers remain, and the benefits of telerehabilitation (TR) are still unclear.

Objective: The objective of this systematic review and meta-analysis was to examine the effect of TR in adults with PD through the International Classification of Functioning, Disability, and Health.

Data sources: An electronic database search (PubMed, EMBASE, SCOPUS, PEDro, Cochrane) was performed for data published from inception to April 2025.

Data selection: Inclusion criteria were randomized controlled trials involving adults with PD, assessing remotely delivered physical activity or physical rehabilitation interventions, compared to control groups not exposed to TR, and reporting outcomes of interest. Exclusion criteria included studies involving additional neurological disorders.

Data extraction and synthesis: Data extraction was guided by the PRISMA guidelines. This review was registered with PROSPERO (CRD42023475545). A risk of bias assessment (RoB-2) and methodological quality assessment (PEDro) tools were used. Data were analyzed using random-effects models.

Main outcomes and measures: The outcomes of interest were balance, gait, functional mobility, physical activity, quality of life (QOL), and social support.

Results: Eighteen studies were included in the final analysis, involving 731 individuals with PD. The most common types of TR included remote-based exergaming and using video conferencing platforms. The results indicated no statistically significant difference between TR and control groups on balance (standardized mean difference [SMD] = 0.31, 95% CI = -0.02 to 0.65), gait speed (SMD = -0.07, 95% CI = -0.33 to 0.19), and functional mobility (SMD = 0.05, 95% CI = -0.27 to 0.37) outcomes. However, the results were statistically in favor of TR for improving QOL (SMD = 0.26, 95% CI = 0.05 to 0.47).

Conclusions and relevance: TR yielded similar or superior results compared to non-exposed control conditions across the 5 outcomes evaluated. Health care providers can decide which method of care delivery they prefer based on patients' preferences and resources.

重要性:康复是治疗帕金森病(PD)的关键,但获取障碍仍然存在,远程康复(TR)的益处仍不清楚。目的:本系统综述和荟萃分析的目的是通过国际功能、残疾和健康分类来检查TR对成年PD患者的影响。数据来源:电子数据库检索(PubMed, EMBASE, SCOPUS, PEDro, Cochrane),检索自成立至2025年4月发表的数据。资料选择:纳入标准为随机对照试验,涉及成年PD患者,评估远程提供的身体活动或身体康复干预,与未接受远程康复的对照组进行比较,并报告感兴趣的结果。排除标准包括涉及其他神经系统疾病的研究。数据提取与综合:数据提取以PRISMA为指导。本综述已在普洛斯彼罗注册(CRD42023475545)。使用偏倚风险评估(rob2)和方法学质量评估(PEDro)工具。数据分析采用随机效应模型。主要结果和测量:感兴趣的结果是平衡、步态、功能活动、身体活动、生活质量和社会支持。结果:18项研究纳入最终分析,涉及731例PD患者。最常见的TR类型包括远程游戏和使用视频会议平台。结果显示,TR组与对照组在平衡(SMD = 0.31, 95% CI = -0.02 ~ 0.65)、步态速度(SMD = -0.07, 95% CI = -0.33 ~ 0.19)和功能活动(SMD = 0.05, 95% CI = -0.27 ~ 0.37)方面无统计学差异。然而,结果在统计学上支持TR改善生活质量(SMD = 0.26, 95% CI = 0.05 ~ 0.47)。结论和相关性:在评估的5个结果中,与非暴露对照条件相比,TR产生了相似或更好的结果。卫生保健提供者可以根据患者的偏好和资源来决定他们喜欢的护理提供方法。
{"title":"Effect of Telerehabilitation in Parkinson Disease: A Systematic Review and Meta-Analysis.","authors":"Paria Darbandsari, Linda S Pescatello, Daniele Piscitelli, James M Smith, Alessandro Ugolini, Cristina Colón-Semenza","doi":"10.1093/ptj/pzaf121","DOIUrl":"10.1093/ptj/pzaf121","url":null,"abstract":"<p><strong>Importance: </strong>Rehabilitation is a key in managing Parkinson disease (PD), but access barriers remain, and the benefits of telerehabilitation (TR) are still unclear.</p><p><strong>Objective: </strong>The objective of this systematic review and meta-analysis was to examine the effect of TR in adults with PD through the International Classification of Functioning, Disability, and Health.</p><p><strong>Data sources: </strong>An electronic database search (PubMed, EMBASE, SCOPUS, PEDro, Cochrane) was performed for data published from inception to April 2025.</p><p><strong>Data selection: </strong>Inclusion criteria were randomized controlled trials involving adults with PD, assessing remotely delivered physical activity or physical rehabilitation interventions, compared to control groups not exposed to TR, and reporting outcomes of interest. Exclusion criteria included studies involving additional neurological disorders.</p><p><strong>Data extraction and synthesis: </strong>Data extraction was guided by the PRISMA guidelines. This review was registered with PROSPERO (CRD42023475545). A risk of bias assessment (RoB-2) and methodological quality assessment (PEDro) tools were used. Data were analyzed using random-effects models.</p><p><strong>Main outcomes and measures: </strong>The outcomes of interest were balance, gait, functional mobility, physical activity, quality of life (QOL), and social support.</p><p><strong>Results: </strong>Eighteen studies were included in the final analysis, involving 731 individuals with PD. The most common types of TR included remote-based exergaming and using video conferencing platforms. The results indicated no statistically significant difference between TR and control groups on balance (standardized mean difference [SMD] = 0.31, 95% CI = -0.02 to 0.65), gait speed (SMD = -0.07, 95% CI = -0.33 to 0.19), and functional mobility (SMD = 0.05, 95% CI = -0.27 to 0.37) outcomes. However, the results were statistically in favor of TR for improving QOL (SMD = 0.26, 95% CI = 0.05 to 0.47).</p><p><strong>Conclusions and relevance: </strong>TR yielded similar or superior results compared to non-exposed control conditions across the 5 outcomes evaluated. Health care providers can decide which method of care delivery they prefer based on patients' preferences and resources.</p>","PeriodicalId":20093,"journal":{"name":"Physical Therapy","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145252196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Behaviorally Informed Interventions to Promote Activity in the Home and Community for Adults With Neurological Disorders: A Systematic Review and Meta-Analysis. 行为知情干预促进家庭和社区活动的成人神经系统疾病:系统回顾和荟萃分析。
IF 3.3 4区 医学 Q1 ORTHOPEDICS Pub Date : 2025-11-03 DOI: 10.1093/ptj/pzaf117
Amber LaMarca, Rania Karim, Gwendolyn Larsen, Ivy Tse, Stephen Wechsler, Lynne V Gauthier, Julie Keysor

Importance: Physical activity can improve clinical outcomes among people with neurological conditions; however, people with these conditions rarely engage in recommended levels of activity. Remote monitoring (RM) with the incorporation of behavior change strategies is purported to be an effective approach to promote increased physical activity in the home setting, however, its effectiveness in promoting activity for people with neurological conditions is unclear.

Objectives: The objectives of this review were to examine the effectiveness of behaviorally informed RM interventions on physical activity in the home and community and to identify usage and impact of specific behavior change techniques (BCTs) implemented with RM interventions.

Data sources: PubMed, PsycINFO, and CINAHL were searched in March 2024.

Study selection: This study included a selection of randomized controlled trials on behaviorally informed RM interventions that use wearable sensors or digital applications to target physical activity for patients with neurological diseases.

Data extraction and synthesis: Data extraction was performed by 2 independent reviewers and data synthesis was performed with random effects meta-analysis. BCT were classified using Michie's behavior change technique taxonomy. Promising BCTs were identified by examining the proportion of statistically significant studies for each technique. Risk of bias was assessed with the risk of bias 2 tool.

Main outcomes and measures: The main outcomes and measures included physical activity measured by self-report and accelerometers.

Results: Fourteen studies were included with some concerns of bias, encompassing individuals with multiple sclerosis, stroke, Parkinson disease, and spinal cord injury. Behaviorally informed RM interventions resulted in statistically significant improvements in self-reported physical activity (SMD = 0.27, 95% CI = 0.06 to 49), but not accelerometry outcomes (SMD = 0.52, 95% CI = -0.07 to 1.11). Promising BCTs included self-monitoring, problem solving, goal setting, graded tasks, social support, and adding objects to the environment.

Conclusions and relevance: RM shows initial promise to increase physical activity of people living with neurological conditions when paired with behavior change consultation.

重要性:体育活动可以改善神经系统疾病患者的临床结果;然而,患有这些疾病的人很少参与建议的活动水平。结合行为改变策略的远程监控(RM)据称是一种促进家庭环境中增加身体活动的有效方法,然而,其在促进神经系统疾病患者活动方面的有效性尚不清楚。目的:本综述的目的是检查行为知情的RM干预对家庭和社区身体活动的有效性,并确定与RM干预一起实施的特定行为改变技术(bct)的使用和影响。数据来源:PubMed、PsycINFO、CINAHL检索时间为2024年3月。研究选择:本研究包括一组随机对照试验,这些试验采用可穿戴传感器或数字应用程序对神经系统疾病患者进行针对性的身体活动。数据提取与综合:数据提取由2名独立审稿人进行,数据综合采用随机效应荟萃分析。使用Michie行为改变技术分类法对行为改变技术进行分类。通过检查每种技术有统计学意义的研究的比例来确定有希望的bct。使用Risk of bias 2工具评估偏倚风险。主要结果和测量方法:主要结果和测量方法包括自我报告和加速度计测量的身体活动。结果:14项研究纳入了一些偏倚的担忧,包括多发性硬化症、中风、帕金森病和脊髓损伤的个体。行为知情的RM干预导致自我报告的身体活动有统计学意义的改善(SMD = 0.27, 95% CI = 0.06至49),但没有加速测量结果(SMD = 0.52, 95% CI = -0.07至1.11)。有希望的btc包括自我监控、问题解决、目标设定、分级任务、社会支持和向环境中添加物体。结论和相关性:远程监测与行为改变咨询相结合,初步显示出增加神经系统疾病患者身体活动的希望。
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引用次数: 0
News From the Foundation for Physical Therapy Research, November 2025. 来自物理治疗研究基金会的消息,2025年11月。
IF 3.3 4区 医学 Q1 ORTHOPEDICS Pub Date : 2025-11-03 DOI: 10.1093/ptj/pzaf127
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引用次数: 0
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Physical Therapy
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