Pub Date : 2021-09-05DOI: 10.1183/13993003.congress-2021.oa1516
E. Schillebeeckx, E. Janssens, V. Surmont, K. Nackaerts, J. V. van Meerbeeck, K. Lamote
{"title":"Breath analysis allows to predict treatment response in malignant pleural mesothelioma patients","authors":"E. Schillebeeckx, E. Janssens, V. Surmont, K. Nackaerts, J. V. van Meerbeeck, K. Lamote","doi":"10.1183/13993003.congress-2021.oa1516","DOIUrl":"https://doi.org/10.1183/13993003.congress-2021.oa1516","url":null,"abstract":"","PeriodicalId":20113,"journal":{"name":"Pleural and Mediastinal Malignancies","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80397553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-05DOI: 10.1183/13993003.congress-2021.pa3100
Janet Rodríguez Torres, L. López-López, María Granados-Santiago, Esther Prados-Román, Alejandro Heredia-Ciuró, M. Valenza
{"title":"Impact of sarcopenia in long-term symptoms in patients with malignant pleural effusion","authors":"Janet Rodríguez Torres, L. López-López, María Granados-Santiago, Esther Prados-Román, Alejandro Heredia-Ciuró, M. Valenza","doi":"10.1183/13993003.congress-2021.pa3100","DOIUrl":"https://doi.org/10.1183/13993003.congress-2021.pa3100","url":null,"abstract":"","PeriodicalId":20113,"journal":{"name":"Pleural and Mediastinal Malignancies","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88478733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-05DOI: 10.1183/13993003.congress-2021.pa3101
Sayed Alderazi, Anne Karanuatilleke, B. Sutton
{"title":"Variation in outcomes for M1a Stage Lung cacers- Outcome in Malingnat Pleural Effusion significantly worse than patients with Contralateral Lung Nodules","authors":"Sayed Alderazi, Anne Karanuatilleke, B. Sutton","doi":"10.1183/13993003.congress-2021.pa3101","DOIUrl":"https://doi.org/10.1183/13993003.congress-2021.pa3101","url":null,"abstract":"","PeriodicalId":20113,"journal":{"name":"Pleural and Mediastinal Malignancies","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72950602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-05DOI: 10.1183/13993003.congress-2021.oa1519
P. Sivakumar, N. Shah, G. Kaltsakas, N. Hart, Patrick J. Murphy, L. Ahmed
{"title":"The relationship between pleural effusion, neural respiratory drive and breathlessness – preliminary results from the SINE study","authors":"P. Sivakumar, N. Shah, G. Kaltsakas, N. Hart, Patrick J. Murphy, L. Ahmed","doi":"10.1183/13993003.congress-2021.oa1519","DOIUrl":"https://doi.org/10.1183/13993003.congress-2021.oa1519","url":null,"abstract":"","PeriodicalId":20113,"journal":{"name":"Pleural and Mediastinal Malignancies","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80115572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-05DOI: 10.1183/13993003.congress-2021.oa1522
K. Ferguson, Nicola Hyndman, F. Roberts, K. Blyth
{"title":"The frequency of BAP1 and MTAP loss in Benign Asbestos-associated Pleural Inflammation","authors":"K. Ferguson, Nicola Hyndman, F. Roberts, K. Blyth","doi":"10.1183/13993003.congress-2021.oa1522","DOIUrl":"https://doi.org/10.1183/13993003.congress-2021.oa1522","url":null,"abstract":"","PeriodicalId":20113,"journal":{"name":"Pleural and Mediastinal Malignancies","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77988343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-05DOI: 10.1183/13993003.congress-2021.oa1520
M. Gadallah, M. Shaheen, S. Mourad, A. Abdelhady, Maged Hassan
{"title":"Intracavitary anaesthesia for medical thoracoscopy: a randomised trial","authors":"M. Gadallah, M. Shaheen, S. Mourad, A. Abdelhady, Maged Hassan","doi":"10.1183/13993003.congress-2021.oa1520","DOIUrl":"https://doi.org/10.1183/13993003.congress-2021.oa1520","url":null,"abstract":"","PeriodicalId":20113,"journal":{"name":"Pleural and Mediastinal Malignancies","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75629694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-28DOI: 10.1183/13993003.congress-2019.oa491
Miguel Iglesias Heras, R. C. Pérez, Juan Alejandro Cascón Hernández, J. Hierro, José Ángel Tapias Del Pozo, T. A. García, Emilio Juárez Moreno, Roberto Fernández Mellado, Esther Yagüe Zapatero, Graciliano Estrada Trigeros, M. Ferrero
{"title":"Feasibility of thoracic ultrasound to assess the withdrawal of the indwelling pleural catheter. Concordance with chest CT scan","authors":"Miguel Iglesias Heras, R. C. Pérez, Juan Alejandro Cascón Hernández, J. Hierro, José Ángel Tapias Del Pozo, T. A. García, Emilio Juárez Moreno, Roberto Fernández Mellado, Esther Yagüe Zapatero, Graciliano Estrada Trigeros, M. Ferrero","doi":"10.1183/13993003.congress-2019.oa491","DOIUrl":"https://doi.org/10.1183/13993003.congress-2019.oa491","url":null,"abstract":"","PeriodicalId":20113,"journal":{"name":"Pleural and Mediastinal Malignancies","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77668953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-28DOI: 10.1183/13993003.congress-2019.oa3794
M. Lui, K. Chiang, Chung-man. Ho, C. Tam, C. Lam, Y. Lee, S. M. Ip
{"title":"Early pleural fluid control is warranted to prevent reaccumulation of malignant pleural effusion in oncogene-driven lung cancer","authors":"M. Lui, K. Chiang, Chung-man. Ho, C. Tam, C. Lam, Y. Lee, S. M. Ip","doi":"10.1183/13993003.congress-2019.oa3794","DOIUrl":"https://doi.org/10.1183/13993003.congress-2019.oa3794","url":null,"abstract":"","PeriodicalId":20113,"journal":{"name":"Pleural and Mediastinal Malignancies","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77232115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-28DOI: 10.1183/13993003.congress-2019.pa3097
E. Romer, L. Watkins, F. Frost, M. Ledson
Introduction: The National Mesothelioma Audit Report 2018 highlighted variability in care of patients diagnosed with malignant mesothelioma (Royal College of Physicians, 2018; 9-11). We reviewed our practice during 2014-2018. Methods: Data for mesothelioma diagnoses in 2014-18 were obtained from the Somerset Cancer Registry and electronic patient records. Results: 59 patient notes were reviewed; 84.7% were male. Mean age was 75 years (range 50-90). Performance status (PS) was recorded in 55 (93.2%). 44 (74.6%) patients had video-assisted thoracoscopic surgery (VATS). 56 (94.9%) had pathological confirmation of mesothelioma; with pathological subtype in 44 (74.6%). 3 patients had no pathological confirmation. 2 were not investigated further due to PS 3; both died within 50 days of diagnosis. 1 had an inconclusive biopsy and the MDT felt histology would not change management. 30 (50.8%) received anti-cancer treatment: 20 (33.9%) chemotherapy, 14 (23.7%) radiotherapy (4 patients both). 17 of 37 patients with PS 0-1 received chemotherapy (45.9%). Conclusion: Audit standards were exceeded in recording PS and obtaining pathological diagnosis, but not in recording pathological subtype (Table 1). Chemotherapy rate was lower than expected despite all PS 0-1 patients being referred to oncology. This could be due to rapidly declining PS or patient choice. The findings highlight the aggressive nature of the disease and impact on treatment options.
导语:2018年国家间皮瘤审计报告强调了恶性间皮瘤患者护理的可变性(皇家医师学院，2018;9 - 11)。我们回顾了2014-2018年的实践。方法:2014-18年间皮瘤诊断数据来自Somerset Cancer Registry和电子病历。结果:回顾59例患者笔记;84.7%为男性。平均年龄75岁(范围50-90岁)。55例(93.2%)记录了绩效状态(PS)。44例(74.6%)患者行电视胸腔镜手术(VATS)。病理证实间皮瘤56例(94.9%);病理亚型44例(74.6%)。3例无病理证实。2例因ps3未进一步调查;两人都在确诊后50天内死亡。我有一个不确定的活检和MDT认为组织学不会改变管理。接受抗癌治疗30例(50.8%)，化疗20例(33.9%)，放疗14例(23.7%)(两者均有4例)。37例PS 0-1患者中有17例(45.9%)接受了化疗。结论:PS记录和病理诊断均超过审计标准，但病理亚型记录未达到审计标准(表1)。尽管PS 0-1患者均转诊至肿瘤科，但化疗率低于预期。这可能是由于快速下降的PS或患者的选择。研究结果强调了该疾病的侵袭性及其对治疗方案的影响。
{"title":"Meeting the National Mesothelioma Audit standards in clinical practice: How achievable is it?","authors":"E. Romer, L. Watkins, F. Frost, M. Ledson","doi":"10.1183/13993003.congress-2019.pa3097","DOIUrl":"https://doi.org/10.1183/13993003.congress-2019.pa3097","url":null,"abstract":"Introduction: The National Mesothelioma Audit Report 2018 highlighted variability in care of patients diagnosed with malignant mesothelioma (Royal College of Physicians, 2018; 9-11). We reviewed our practice during 2014-2018. Methods: Data for mesothelioma diagnoses in 2014-18 were obtained from the Somerset Cancer Registry and electronic patient records. Results: 59 patient notes were reviewed; 84.7% were male. Mean age was 75 years (range 50-90). Performance status (PS) was recorded in 55 (93.2%). 44 (74.6%) patients had video-assisted thoracoscopic surgery (VATS). 56 (94.9%) had pathological confirmation of mesothelioma; with pathological subtype in 44 (74.6%). 3 patients had no pathological confirmation. 2 were not investigated further due to PS 3; both died within 50 days of diagnosis. 1 had an inconclusive biopsy and the MDT felt histology would not change management. 30 (50.8%) received anti-cancer treatment: 20 (33.9%) chemotherapy, 14 (23.7%) radiotherapy (4 patients both). 17 of 37 patients with PS 0-1 received chemotherapy (45.9%). Conclusion: Audit standards were exceeded in recording PS and obtaining pathological diagnosis, but not in recording pathological subtype (Table 1). Chemotherapy rate was lower than expected despite all PS 0-1 patients being referred to oncology. This could be due to rapidly declining PS or patient choice. The findings highlight the aggressive nature of the disease and impact on treatment options.","PeriodicalId":20113,"journal":{"name":"Pleural and Mediastinal Malignancies","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89875133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-28DOI: 10.1183/13993003.congress-2019.pa3093
Carmen Tan, P. Quek, R. Chang
Background: Malignant pleural effusion (MPE) is a rising healthcare burden requiring inpatient care. Variation in clinical practice results in prolonged length of stay (LOS) for this vulnerable group where life expectancy is already compromised. Chest tube drainage remains the preferred local treatment with talc pleurodesis being performed as guided by patients’ suitability and preference. An institution-based clinical audit in 2016 revealed a median effusion related LOS of >7 days. This review aims to identify factors contributing to prolonged pleural drainage and implement strategies to improve management of MPE by reducing hospital stay. Methods: We identified factors of delay in chest tube removal from baseline data (n=53) and implemented targeted interventions over 3 months: 1. Spreading the word to stakeholders (Respiratory Medicine, Palliative Medicine, General Medicine, Radiology) involved; 2. Collaboration with Pathology/molecular laboratory for timely reporting of results; 3. Regular reminder and education of clinical staff regarding evidence-based practice; 4. Implementation of a practical guide/checklist for chest tube management and talc pleurodesis; 5. Talc pleurodesis Procedure Information Sheet. Results: The data of 61 patients during and post intervention between 1 Jun 2017 and 28 Feb 2018 was analysed. Median effusion related LOS decreased from >7 to 5 days. This improvement continued to sustain 6 months after implementation of all interventions. Conclusion: Through education and collaborative efforts in building partnerships, we achieved success in improving management of MPE and reducing effusion related LOS whilst maintaining quality care.
{"title":"Understanding how variation in clinical practice affects length of stay for patients with malignant pleural effusion","authors":"Carmen Tan, P. Quek, R. Chang","doi":"10.1183/13993003.congress-2019.pa3093","DOIUrl":"https://doi.org/10.1183/13993003.congress-2019.pa3093","url":null,"abstract":"Background: Malignant pleural effusion (MPE) is a rising healthcare burden requiring inpatient care. Variation in clinical practice results in prolonged length of stay (LOS) for this vulnerable group where life expectancy is already compromised. Chest tube drainage remains the preferred local treatment with talc pleurodesis being performed as guided by patients’ suitability and preference. An institution-based clinical audit in 2016 revealed a median effusion related LOS of >7 days. This review aims to identify factors contributing to prolonged pleural drainage and implement strategies to improve management of MPE by reducing hospital stay. Methods: We identified factors of delay in chest tube removal from baseline data (n=53) and implemented targeted interventions over 3 months: 1. Spreading the word to stakeholders (Respiratory Medicine, Palliative Medicine, General Medicine, Radiology) involved; 2. Collaboration with Pathology/molecular laboratory for timely reporting of results; 3. Regular reminder and education of clinical staff regarding evidence-based practice; 4. Implementation of a practical guide/checklist for chest tube management and talc pleurodesis; 5. Talc pleurodesis Procedure Information Sheet. Results: The data of 61 patients during and post intervention between 1 Jun 2017 and 28 Feb 2018 was analysed. Median effusion related LOS decreased from >7 to 5 days. This improvement continued to sustain 6 months after implementation of all interventions. Conclusion: Through education and collaborative efforts in building partnerships, we achieved success in improving management of MPE and reducing effusion related LOS whilst maintaining quality care.","PeriodicalId":20113,"journal":{"name":"Pleural and Mediastinal Malignancies","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75747519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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