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Collective effects in flow-driven cell migration 流动驱动细胞迁移中的集体效应
Pub Date : 2023-11-13 DOI: 10.1103/physreve.108.054406
Louis González, Andrew Mugler
Autologous chemotaxis is the process in which cells secrete and detect molecules to determine the direction of fluid flow. Experiments and theory suggest that autologous chemotaxis fails at high cell densities because molecules from other cells interfere with a given cell's signal. We investigate autologous chemotaxis using a three-dimensional Monte Carlo-based motility simulation that couples spatial and temporal gradient sensing with cell-cell repulsion. Surprisingly, we find that when temporal gradient sensing dominates, high-density clusters chemotax faster than individual cells. To explain this observation, we propose a mechanism by which temporal gradient sensing allows cells to form a collective sensory unit. We demonstrate using computational fluid mechanics that that this mechanism indeed allows a cluster of cells to outperform single cells in terms of the detected anisotropy of the signal, a finding that we demonstrate with analytic scaling arguments. Our work suggests that collective autologous chemotaxis at high cell densities is possible and requires only known, ubiquitous cell capabilities.
自体趋化是细胞分泌和检测分子以确定流体流动方向的过程。实验和理论表明,由于来自其他细胞的分子干扰了给定细胞的信号,自体趋化性在高细胞密度下失效。我们使用三维蒙特卡罗运动模拟来研究自体趋化性,该模拟将空间和时间梯度传感与细胞-细胞排斥相结合。令人惊讶的是,我们发现当时间梯度传感占主导地位时,高密度集群比单个细胞更快地趋化。为了解释这一观察结果,我们提出了一种机制,通过这种机制,时间梯度传感允许细胞形成一个集体的感觉单元。我们使用计算流体力学证明,这种机制确实允许细胞簇在检测信号的各向异性方面优于单个细胞,我们用解析缩放论证证明了这一发现。我们的工作表明,在高细胞密度下,集体自体趋化是可能的,只需要已知的、普遍存在的细胞能力。
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引用次数: 0
Gap solitons and nonlinear Bloch states in Bose-Einstein condensates with current-dependent interactions 具有电流依赖相互作用的玻色-爱因斯坦凝聚中的间隙孤子和非线性布洛赫态
Pub Date : 2023-11-13 DOI: 10.1103/physreva.108.053313
Jintao Xu, Qian Jia, Haibo Qiu, Antonio Muñoz Mateo
We show how the chiral properties of Bose-Einstein condensates subject to current-density interactions and loaded in optical lattices can be observed in the realization of nonlinear Bloch states, whose spectrum lacks the usual periodic structure. Chirality is also manifested by spatially localized states, or gap solitons, which are found for positive rotation rates of the lattice at the energy gaps between the linear energy bands, whereas for negative rotations they appear in the semi-infinite gap of the linear spectrum. The stability of extended and localized states is checked through the spectrum of linear excitations and nonlinear time evolution of perturbed states, and the phenomenon of Bloch oscillations is explored. Our results are obtained in quasi-one-dimensional ring geometries with feasible experimental parameters.
我们展示了如何在非线性布洛赫态的实现中观察到受电流密度相互作用和加载在光学晶格中的玻色-爱因斯坦凝聚体的手性,其光谱缺乏通常的周期结构。手性还表现为空间局域化态或间隙孤子,它们在线性能带之间的能量间隙处发现晶格的正旋转速率,而对于负旋转它们出现在线性谱的半无限间隙中。通过线性激励谱和摄动态的非线性时间演化检验了扩展态和局域态的稳定性,并探讨了布洛赫振荡现象。我们的结果是在具有可行实验参数的准一维环几何上得到的。
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引用次数: 0
Pseudo electric field and pumping valley current in graphene nanobubbles 石墨烯纳米泡中的赝电场与抽运谷电流
Pub Date : 2023-11-13 DOI: 10.1103/physrevb.108.195418
Naif Hadadi, Adel Belayadi, Ahmed AlRabiah, Ousmane Ly, Collins Ashu Akosa, Michael Vogl, Hocine Bahlouli, Aurelien Manchon, Adel Abbout
The extremely high pseudo magnetic field emerging in strained graphene suggests that an oscillating nanodeformation will induce a very high current even without electric bias. In this paper, we demonstrate the subterahertz (THz) dynamics of a valley current and the corresponding charge pumping with a periodically excited nanobubble. We discuss the amplitude of the pseudo electric field and investigate the dependence of the pumped valley current on the different parameters of the system. Finally, we report the signature of extra-harmonics generation in the valley current that might lead to potential modern device development operating in the nonlinear regime.
应变石墨烯中出现的极高伪磁场表明,即使没有电偏置,振荡纳米变形也会产生非常高的电流。在本文中,我们证明了谷电流的亚太赫兹(THz)动力学和相应的电荷泵浦与周期性激发的纳米泡。讨论了赝电场的幅值,并研究了泵浦谷电流对系统不同参数的依赖关系。最后,我们报告了谷电流中产生的额外谐波的特征,这可能导致在非线性状态下工作的潜在现代器件开发。
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引用次数: 1
General limit to thermodynamic annealing performance 热力学退火性能的一般限制
Pub Date : 2023-11-13 DOI: 10.1103/physreve.108.l052105
Yutong Luo, Yi-Zheng Zhen, Xiangjing Liu, Daniel Ebler, Oscar Dahlsten
Annealing has proven highly successful in finding minima in a cost landscape. Yet, depending on the landscape, systems often converge towards local minima rather than global ones. In this Letter, we analyze the conditions for which annealing is approximately successful in finite time. We connect annealing to stochastic thermodynamics to derive a general bound on the distance between the system state at the end of the annealing and the ground state of the landscape. This distance depends on the amount of state updates of the system and the accumulation of nonequilibrium energy, two protocol and energy landscape-dependent quantities which we show are in a trade-off relation. We describe how to bound the two quantities both analytically and physically. This offers a general approach to assess the performance of annealing from accessible parameters, both for simulated and physical implementations.
退火在寻找成本最小值方面已经被证明是非常成功的。然而,取决于景观,系统往往收敛于局部最小值,而不是全局最小值。在这封信中,我们分析了退火在有限时间内近似成功的条件。我们将退火与随机热力学联系起来,以推导出退火结束时系统状态与景观基态之间距离的一般界限。这个距离取决于系统状态更新的数量和非平衡能量的积累,我们表明,两个协议和能量景观依赖的量是一种权衡关系。我们描述了如何在分析上和物理上结合这两个量。这为模拟和物理实现提供了一种从可访问参数评估退火性能的一般方法。
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引用次数: 1
Os16+ and Ir17+ ions as candidates for accurate optical clocks sensitive to physics beyond the standard model Os16+和Ir17+离子作为对标准模型之外的物理敏感的精确光学时钟的候选者
Pub Date : 2023-11-13 DOI: 10.1103/physreva.108.053111
V. A. Dzuba, V. V. Flambaum
We perform detailed calculations of the electronic structure of the ${mathrm{Os}}^{16+}$ ion and demonstrate that it has several metastable states which can be used for very accurate optical clocks. The clocks are highly sensitive to manifestations of the physics beyond the standard model, such as time variation of the fine-structure constant $ensuremath{alpha}$, interaction with scalar and pseudoscalar (axion) dark matter fields, local Lorentz invariance and local position invariance violations, and interaction of atomic electrons with a nucleus mediated by a new boson. The latter can be studied by analyzing the King plot for isotope shifts and its possible nonlinearities since Os has five stable isotopes with zero nuclear spin. Similar calculations for the ${mathrm{Ir}}^{17+}$ ion spectra demonstrate good agreement between theory and experiment. This helps to validate the method of the calculations and demonstrate that both ions are excellent candidates for the search for new physics.
我们对${ maththrm {Os}}^{16+}$离子的电子结构进行了详细的计算,并证明它具有几个亚稳态,可以用于非常精确的光学时钟。这些时钟对标准模型之外的物理表现非常敏感,例如精细结构常数$ensuremath{alpha}$的时间变化,与标量和伪标量(轴子)暗物质场的相互作用,局部洛伦兹不变性和局部位置不变性的违反,以及原子电子与由新玻色子中介的原子核的相互作用。后者可以通过分析同位素位移的King图及其可能的非线性来研究,因为Os有五个核自旋为零的稳定同位素。对${mathrm{Ir}}^{17+}$离子谱的类似计算表明理论与实验吻合良好。这有助于验证计算方法,并证明这两种离子都是寻找新物理学的优秀候选者。
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引用次数: 1
Poly( N -isopropylacrylamide) microgel swelling behavior and suspension structure studied with small-angle neutron scattering 用小角中子散射研究了聚N -异丙基丙烯酰胺微凝胶的溶胀行为和悬浮结构
Pub Date : 2023-11-13 DOI: 10.1103/physreve.108.054604
B. Zhou, U. Gasser, A. Fernandez-Nieves
Microgels are of high interest for applications and as model systems due to their volume response to external stimuli. We use small-angle neutron scattering to measure the form and structure factors of poly($N$-isopropylacrylamide) microgels in dilute and concentrated suspensions and find that microgels keep a constant size up to a concentration, above which they deswell. This happens before random-close packing. We emphasize suspension polydispersity must be considered to obtain accurate form and structure factors. Our results are compatible with microgel deswelling triggered by the osmotic pressure set by counterions associated to charged groups in the microgel periphery, which sharply increases when the counterion clouds surrounding the microgels percolate throughout the suspension volume.
微凝胶由于其对外部刺激的体积响应而引起了应用和模型系统的高度兴趣。我们用小角中子散射测量了聚(N$-异丙基丙烯酰胺)微凝胶在稀悬液和浓悬液中的形态和结构因素,发现微凝胶在一定的浓度下保持恒定的尺寸,超过一定的浓度就会分解。这发生在随机封闭打包之前。我们强调必须考虑悬浮液的多分散性,以获得准确的形式和结构因素。我们的结果与微凝胶由与微凝胶外围带电基团相关的反离子设定的渗透压触发的微凝胶溶胀相一致,当微凝胶周围的反离子云渗透到整个悬浮液体积时,渗透压急剧增加。
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引用次数: 0
Deterministic generation of phononic Fock states via weak nonlinearities 弱非线性声子Fock态的确定性生成
Pub Date : 2023-11-13 DOI: 10.1103/physreva.108.053709
Yi-Xuan Ma, Peng-Bo Li
We propose an efficient method to generate single-phonon Fock states by exploiting a previously unidentified phonon blockade mechanism in a hybrid spin-mechanical system. Specifically, this mechanism makes use of arbitrarily weak Duffing nonlinearity to modify matrix elements of an effective phonon excitation process, assisted by both one- and two-phonon drives. The weak Duffing nonlinearity of the phonons is induced by a nitrogen-vacancy (NV) center magnetically coupled to a cantilever, while the mechanical parametric driving is realized by modulating the spring constant of the cantilever using a pump. By implementing a time-dependent protocol for the linear and parametric drives, there exists a strict cutoff in the phonon number distribution, resulting in a pure Fock state. Furthermore, the nonclassical nature of the generated state remains robust against dissipations.
我们提出了一种有效的方法来产生单声子Fock态,利用以前未知的声子封锁机制在混合自旋机械系统。具体而言,该机制利用任意弱Duffing非线性来修改有效声子激发过程的矩阵元素,并辅以单声子和双声子驱动。声子的弱Duffing非线性是由氮空位(NV)中心与悬臂梁的磁耦合引起的,而机械参数驱动是通过泵浦调制悬臂梁的弹簧常数实现的。通过实现线性和参数驱动的时间相关协议,在声子数分布中存在严格的截止,导致纯Fock状态。此外,生成态的非经典性质对耗散保持鲁棒性。
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引用次数: 0
Simulating the Berezinskii-Kosterlitz-Thouless transition with the complex Langevin algorithm 用复朗格万算法模拟Berezinskii-Kosterlitz-Thouless转换
Pub Date : 2023-11-13 DOI: 10.1103/physreva.108.053311
Philipp Heinen, Thomas Gasenzer
Numerical simulations of the full quantum properties of interacting many-body systems by means of field-theoretic Monte Carlo techniques are often limited due to a sign problem. Here we simulate properties of a dilute two-dimensional Bose gas in the vicinity of the Berezinskii-Kosterlitz-Thouless (BKT) transition by means of the complex Langevin (CL) algorithm, thereby extending our previous CL study of the three-dimensional Bose gas to the lower-dimensional case. The purpose of the paper is twofold. On the one hand, it adds to benchmarking of the CL method and thus contributes to further exploring the range of applicability of the method. With the respective results, the universality of the equation of state is recovered, as well as the long-wave-length power-law dependence of the single-particle momentum spectrum below the BKT transition. Analysis of the rotational part of the current density corroborates vortex unbinding in crossing the transition. Beyond these measures of consistency we compute quantum corrections to the critical density and chemical potential in the weakly coupled regime. Our results show a shift of these quantities to lower values as compared to those obtained from classical field theory. It points in the opposite direction as compared to the shift of the critical density found by means of the path-integral Monte Carlo method at larger values of the coupling. Our simulations widen the perspective for precision comparisons with experiment.
利用场论蒙特卡罗技术对相互作用的多体系统的全量子特性进行数值模拟常常受到符号问题的限制。在这里,我们利用复朗格万(CL)算法模拟了berezinski - kosterlitz - thouless (BKT)跃迁附近的稀释二维玻色气体的性质,从而将我们之前对三维玻色气体的CL研究扩展到低维情况。这篇论文的目的是双重的。一方面,它增加了CL方法的基准测试,从而有助于进一步探索该方法的适用范围。通过各自的结果,恢复了状态方程的普适性,以及BKT跃迁下单粒子动量谱的长波幂律依赖性。对电流密度旋转部分的分析证实了涡旋在穿越跃迁时的解除。除了这些一致性测量之外,我们还计算了弱耦合状态下临界密度和化学势的量子修正。我们的结果表明,与从经典场论得到的结果相比,这些量向更低的值转移。与路径积分蒙特卡罗方法在较大的耦合值下发现的临界密度的位移相比,它指向相反的方向。我们的模拟拓宽了与实验精度比较的视角。
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引用次数: 0
Optimizing resetting of superconducting qubits 优化超导量子比特的重置
Pub Date : 2023-11-13 DOI: 10.1103/physreva.108.052605
Ciro Micheletti Diniz, Rogério Jorge de Assis, Norton G. de Almeida, Celso J. Villas-Boas
Many quantum algorithms demand a large number of repetitions to obtain reliable statistical results. Thus, at each repetition it is necessary to reset the qubits efficiently and precisely in the shortest possible time, so that quantum computers actually have advantages over classical ones. In this work, we perform a detailed analysis of three different models for information resetting in superconducting qubits. Our experimental setup consists of a main qubit coupled to different auxiliary dissipative systems, which are employed in order to perform the erasure of the information of the main qubit. Our analysis shows that it is not enough to increase the coupling and the dissipation rate associated with the auxiliary systems to decrease the resetting time of the main qubit, a fact that motivates us to find the optimal set of parameters for each studied approach, allowing a significant decrease in the reset time of the three models analyzed.
许多量子算法需要大量的重复来获得可靠的统计结果。因此,在每次重复时,有必要在尽可能短的时间内有效而精确地重置量子位,这样量子计算机实际上就比传统计算机具有优势。在这项工作中,我们对超导量子比特中三种不同的信息重置模型进行了详细的分析。我们的实验装置由一个主量子比特耦合到不同的辅助耗散系统组成,这些辅助耗散系统用于执行主量子比特的信息擦除。我们的分析表明,增加与辅助系统相关的耦合和耗散率不足以减少主量子位的重置时间,这一事实促使我们为每种研究方法找到最优参数集,从而使所分析的三种模型的重置时间显着减少。
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引用次数: 0
Bound on annealing performance from stochastic thermodynamics, with application to simulated annealing 结合随机热力学的退火性能,并应用于模拟退火
Pub Date : 2023-11-13 DOI: 10.1103/physreve.108.054119
Yutong Luo, Yi-Zheng Zhen, Xiangjing Liu, Daniel Ebler, Oscar Dahlsten
Annealing is the process of gradually lowering the temperature of a system to guide it towards its lowest energy states. In an accompanying paper [Y. Luo et al., Phys. Rev. E 108, L052105 (2023)], we derived a general bound on annealing performance by connecting annealing with stochastic thermodynamics tools, including a speed limit on state transformation from entropy production. We here describe the derivation of the general bound in detail. In addition, we analyze the case of simulated annealing with Glauber dynamics in depth. We show how to bound the two case-specific quantities appearing in the bound, namely the activity, a measure of the number of microstate jumps, and the change in relative entropy between the state and the instantaneous thermal state, which is due to temperature variation. We exemplify the arguments by numerical simulations on the Sherrington-Kirkpatrick (SK) model of spin glasses.
退火是逐渐降低系统温度以引导其达到最低能态的过程。在一篇随附的论文中[Y.]罗等人,物理学。Rev. E 108, L052105(2023)],我们通过将退火与随机热力学工具联系起来,推导出退火性能的一般界,包括熵产生状态转换的速度限制。我们在这里详细地描述了一般界的推导。此外,我们还深入分析了采用Glauber动力学进行模拟退火的情况。我们展示了如何绑定出现在边界中的两个特定情况的量,即活度,微状态跳跃数量的度量,以及状态与瞬时热状态之间的相对熵变化,这是由于温度变化引起的。我们通过对自旋玻璃的谢林顿-柯克帕特里克(SK)模型的数值模拟来举例说明这些论点。
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引用次数: 1
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Physical Review
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