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Reconfigurable neural spiking in bias field free spin Hall nano-oscillator 偏置场自由自旋霍尔纳米振荡器中的可重构神经尖峰
Pub Date : 2023-11-14 DOI: 10.1103/physrevb.108.184411
Sourabh Manna, Rohit Medwal, Rajdeep Singh Rawat
In this paper, we theoretically investigate neuronlike spiking dynamics in an elliptic ferromagnet (FM)/heavy metal bilayer-based spin Hall nano-oscillator (SHNO) in a bias field free condition, very suitable for practical realization of brain-inspired computing schemes. We demonstrate regular periodic spiking with tunable frequency as well as the leaky integrate-and-fire (LIF) behavior in a single SHNO by manipulating the pulse features of input current. The frequency of regular periodic spiking is tunable in a range of 0.5--0.96 GHz (460 MHz bandwidth) through adjusting the magnitude of constant input DC current density. We further demonstrate the reconfigurability of spiking dynamics in response to a time-varying input accomplished by continuously increasing the input current density as a linear function of time. Macrospin theory and micromagnetic simulation provide insight into the origin of bias field free auto-oscillation and the spiking phenomena in our SHNO. In addition, we discuss how the shape anisotropy of the elliptic FM influence the bias field free auto-oscillation characteristics, including threshold current, frequency, and transition from in-plane to out-of-plane precession. The SHNO operates $<{10}^{12}phantom{rule{0.16em}{0ex}}mathrm{A}/{mathrm{m}}^{2}$ input current density and exhibits a large auto-oscillation amplitude, ensuring high output power. We show that the threshold current density can be reduced by decreasing the ellipticity of the FM layer as well as enhancing the perpendicular magnetic anisotropy. These findings highlight the potential of bias field free elliptic SHNO in designing power-efficient spiking neuron-based neuromorphic hardware.
本文从理论上研究了椭圆型铁磁体(FM)/重金属双层自旋霍尔纳米振荡器(SHNO)在无偏置场条件下的类神经元脉冲动力学,该振荡器非常适合于脑启发计算方案的实际实现。通过控制输入电流的脉冲特性,我们展示了在单个SHNO中具有可调频率的规则周期性尖峰以及漏积起火(LIF)行为。通过调节恒定输入直流电流密度的大小,可以在0.5—0.96 GHz (460 MHz带宽)范围内调节规则周期尖峰的频率。我们进一步证明了响应时变输入的尖峰动力学的可重构性,通过连续增加输入电流密度作为时间的线性函数来实现。宏自旋理论和微磁模拟揭示了我们的SHNO中无偏置场自振荡和尖峰现象的起源。此外,我们还讨论了椭圆调频的形状各向异性如何影响无偏置场的自振荡特性,包括阈值电流、频率以及从面内进动到面外进动的过渡。SHNO运行$<{10}^{12}phantom{rule{0.16em}{0ex}}mathrm{A}/{mathrm{m}}^{2}$输入电流密度,具有较大的自振荡幅度,保证了高输出功率。结果表明,通过减小调频层的椭圆度和提高垂直磁各向异性可以降低阈值电流密度。这些发现强调了无偏置场的椭圆SHNO在设计高能效的基于尖峰神经元的神经形态硬件方面的潜力。
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引用次数: 0
Epistasis and pleiotropy shape biophysical protein subspaces associated with drug resistance 上位性和多效性形成与耐药相关的生物物理蛋白亚空间
Pub Date : 2023-11-14 DOI: 10.1103/physreve.108.054408
C. Brandon Ogbunugafor, Rafael F. Guerrero, Miles D. Miller-Dickson, Eugene I. Shakhnovich, Matthew D. Shoulders
Protein space is a rich analogy for genotype-phenotype maps, where amino acid sequence is organized into a high-dimensional space that highlights the connectivity between protein variants. It is a useful abstraction for understanding the process of evolution, and for efforts to engineer proteins towards desirable phenotypes. Few mentions of protein space consider how protein phenotypes can be described in terms of their biophysical components, nor do they rigorously interrogate how forces like epistasis---describing the nonlinear interaction between mutations and their phenotypic consequences---manifest across these components. In this study, we deconstruct a low-dimensional protein space of a bacterial enzyme (dihydrofolate reductase; DHFR) into ``subspaces'' corresponding to a set of kinetic and thermodynamic traits [${k}_{mathrm{cat}}, {K}_{M}, {K}_{i}$, and ${T}_{m}$ (melting temperature)]. We then examine how combinations of three mutations (eight alleles in total) display pleiotropy, or unique effects on individual subspace traits. We examine protein spaces across three orthologous DHFR enzymes (Escherichia coli, Listeria grayi, and Chlamydia muridarum), adding a genotypic context dimension through which epistasis occurs across subspaces. In doing so, we reveal that protein space is a deceptively complex notion, and that future applications to bioengineering should consider how interactions between amino acid substitutions manifest across different phenotypic subspaces.
蛋白质空间是基因型-表型图谱的丰富类比,其中氨基酸序列被组织成高维空间,突出了蛋白质变体之间的连通性。这是一个有用的抽象来理解进化过程,并努力工程蛋白质向理想的表型。很少有人提到蛋白质空间,考虑如何用它们的生物物理成分来描述蛋白质表型,也没有严格地询问诸如作用(描述突变及其表型后果之间的非线性相互作用)之类的力量如何在这些成分中表现出来。在这项研究中,我们解构了细菌酶的低维蛋白质空间(二氢叶酸还原酶;DHFR)转化为对应于一组动力学和热力学特征的“子空间”[${k}_{ mathm {cat}}, {k}_{M}, {k}_{i}$,和${T}_{M} $(熔化温度)]。然后,我们研究了三个突变(总共八个等位基因)的组合如何显示多效性,或对单个子空间性状的独特影响。我们研究了三种同源DHFR酶(大肠杆菌、灰色李斯特菌和muridarum衣原体)的蛋白质空间,增加了基因型背景维度,通过该维度,上位性发生在亚空间中。在这样做的过程中,我们揭示了蛋白质空间是一个看似复杂的概念,未来在生物工程中的应用应该考虑氨基酸取代之间的相互作用如何在不同的表型亚空间中表现出来。
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引用次数: 0
Enhanced chiral edge currents and orbital magnetic moment in chiral d -wave superconductors from mesoscopic finite-size effects 介观有限尺寸效应下手性d波超导体中增强的手性边缘电流和轨道磁矩
Pub Date : 2023-11-14 DOI: 10.1103/physrevb.108.174505
P. Holmvall, A. M. Black-Schaffer
Chiral superconductors spontaneously break time-reversal symmetry and host topologically protected edge modes, supposedly generating chiral edge currents which are typically taken as a characteristic fingerprint of chiral superconductivity. However, recent studies have shown that the total edge current in two dimensions (2D) often vanishes for all chiral superconductors except for chiral $p$-wave, especially at low temperatures, thus severely impeding potential experimental verification and characterization of these superconductors. In this work, we use the quasiclassical theory of superconductivity to study mesoscopic disk-schaped chiral $d$-wave superconductors. We find that mesoscopic finite-size effects cause a dramatic enhancement of the total charge current and orbital magnetic moment (OMM), even at low temperatures. We study how these quantities scale with temperature, spontaneous Meissner screening, and system radius $mathcal{R}ensuremath{in}[5,200]{ensuremath{xi}}_{0}$ with superconducting coherence length ${ensuremath{xi}}_{0}$. We find a general $1/mathcal{R}$ scaling in the total charge current and OMM for sufficiently large systems, but this breaks down in small systems, instead producing a local maximum at $mathcal{R}ensuremath{approx}10--20{ensuremath{xi}}_{0}$ due to mesoscopic finite-size effects. These effects also cause a spontaneous charge-current reversal opposite to the chirality below $mathcal{R}<10{ensuremath{xi}}_{0}$. Our work highlights mesoscopic systems as a route to experimentally verify chiral $d$-wave superconductivity, measurable with magnetometry.
手性超导体自发地打破时间反转对称性,并拥有拓扑保护的边缘模式,产生手性边缘电流,这通常被视为手性超导的特征指纹。然而,最近的研究表明,除了手性$p$ -波之外,所有的手性超导体在二维(2D)中的总边缘电流经常消失,特别是在低温下,从而严重阻碍了这些超导体的潜在实验验证和表征。在这项工作中,我们使用超导的准经典理论来研究介观盘形手性$d$波超导体。我们发现,即使在低温下,介观有限尺寸效应也会导致总电荷电流和轨道磁矩(OMM)的显著增强。我们研究了这些量如何随温度、自发迈斯纳筛选和系统半径$mathcal{R}ensuremath{in}[5,200]{ensuremath{xi}}_{0}$与超导相干长度${ensuremath{xi}}_{0}$的比例。我们发现在足够大的系统中,总电荷电流和OMM普遍$1/mathcal{R}$缩放,但在小系统中,由于介观有限尺寸效应,这种情况会打破,而是在$mathcal{R}ensuremath{approx}10--20{ensuremath{xi}}_{0}$处产生局部最大值。这些效应也会引起自发的电荷-电流反转,与$mathcal{R}<10{ensuremath{xi}}_{0}$下面的手性相反。我们的工作强调介观系统作为实验验证手性$d$ -波超导性的途径,可通过磁强计测量。
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引用次数: 0
Effective mass and interaction energy of heavy Bose polarons at unitarity 重玻色极化子的有效质量和相互作用能
Pub Date : 2023-11-14 DOI: 10.1103/physreva.108.l051301
Nikolay Yegovtsev, Victor Gurarie
The authors study the effective mass of a heavy impurity moving through a Bose-Einstein condensate, and the condensate-induced attraction between two such impurities in the regime of strong boson-impurity interactions. This problem turns out to be analytically solvable in the regime of small gas densities.
作者研究了通过玻色子-爱因斯坦凝聚体的重杂质的有效质量,以及在强玻色子-杂质相互作用下,凝聚体诱导的两个这样的杂质之间的吸引力。这个问题在气体密度小的情况下是可以解析解决的。
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引用次数: 2
Enhanced optomechanical interaction in an unbalanced Michelson-Sagnac interferometer 非平衡Michelson-Sagnac干涉仪中增强的光-力相互作用
Pub Date : 2023-11-14 DOI: 10.1103/physreva.108.053507
Alexandr Karpenko, Mikhail Korobko, Sergey P. Vyatchanin
Quantum optomechanical systems enable the study of fundamental questions on the quantum nature of massive objects. For that a strong coupling between light and mechanical motion is required, which presents a challenge for massive objects. In particular, large interferometric sensors with low-frequency oscillators are difficult to bring into the quantum regime. Here we propose unbalancing the central beam splitter in the Michelson-Sagnac interferometer, which allows us to boost the optomechanical coupling strength compared with a balanced beam splitter. This unbalancing allows us to enhance the cooperative action of two types of optomechanical coupling present in the system: dissipative and dispersive. We analyze two different configurations, in which the optomechanical cavity is formed by the mirror for the laser pump field (power recycling) and by the mirror for the signal field (signal recycling). We show that the imbalance of the beam splitter allows us to dramatically increase the optical cooling of the test-mass motion. We also formulate the conditions for observing quantum radiation-pressure noise and ponderomotive squeezing. Our configuration could serve as the basis for more complex modifications of the interferometer that would utilize the enhanced coupling strength. This would allow us to efficiently reach the quantum state of large test masses, opening the way to studying the fundamental aspects of quantum mechanics and the experimental search for quantum gravity.
量子光力学系统使研究大质量物体的量子性质的基本问题成为可能。为此,需要光和机械运动之间的强耦合,这对大质量物体提出了挑战。特别是,具有低频振荡器的大型干涉传感器很难引入量子状态。本文提出了在Michelson-Sagnac干涉仪中不平衡中央分束器,与平衡分束器相比,这使我们能够提高光机械耦合强度。这种不平衡使我们能够增强系统中存在的两种类型的光-机械耦合的合作作用:耗散和色散。我们分析了两种不同的光机械腔结构,即由激光泵浦场反射镜(功率回收)和信号场反射镜(信号回收)组成的光机械腔。我们表明,分束器的不平衡使我们能够显著地增加测试质量运动的光学冷却。我们还给出了观测量子辐射压力噪声和有源压缩的条件。我们的结构可以作为对干涉仪进行更复杂修改的基础,以利用增强的耦合强度。这将使我们能够有效地达到大测试质量的量子态,为研究量子力学的基本方面和量子引力的实验研究开辟了道路。
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引用次数: 0
Bottom-up approach to room-temperature quantum systems 室温量子系统的自底向上方法
Pub Date : 2023-11-14 DOI: 10.1103/physreva.108.053710
Bochao Wei, Chao Li, Ce Pei, Chandra Raman
We demonstrate a key ingredient in a bottom-up approach to building complex quantum matter using thermal atomic vapors. We isolate and track very slowly moving individual atoms without the aid of laser cooling. Passive filtering enables us to carefully select atoms whose three-dimensional velocity vector has a magnitude below $overline{v}/20$, where $overline{v}$ is the mean velocity of the ensemble. Using a photon correlation technique, we can extract the velocity distributions. We can also follow the trajectory of slowly moving single atoms for more than $1phantom{rule{4pt}{0ex}}textmu{}mathrm{s}$ within a $25text{ensuremath{-}}textmu{}mathrm{m}$ field of view, with no obvious limit to the tracking ability while simultaneously observing Rabi oscillations of these single emitters. In addition, we measure the third-order correlation function of single thermal atoms. Our results demonstrate the power and scalability of thermal ensembles for utilization in quantum memories, imaging, and other quantum information applications through bottom-up approaches.
我们展示了一个关键的成分在自下而上的方法来构建复杂的量子物质使用热原子蒸汽。我们在没有激光冷却的情况下,分离并追踪非常缓慢运动的单个原子。无源滤波使我们能够仔细地选择其三维速度矢量的量级低于$overline{v}/20$的原子,其中$overline{v}$是系综的平均速度。利用光子相关技术,我们可以提取速度分布。我们还可以在$25text{ensuremath{-}}textmu{}mathrm{m}$视场内跟踪超过$1phantom{rule{4pt}{0ex}}textmu{}mathrm{s}$的缓慢移动的单个原子的轨迹,同时观察这些单个发射器的拉比振荡,对跟踪能力没有明显的限制。此外,我们还测量了单热原子的三阶相关函数。我们的研究结果通过自下而上的方法证明了热集成在量子存储器、成像和其他量子信息应用中的强大功能和可扩展性。
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引用次数: 0
Soliton approximation in continuum models of leader-follower behavior 领导-追随者行为连续模型中的孤子近似
Pub Date : 2023-11-14 DOI: 10.1103/physreve.108.054407
F. Terragni, W. D. Martinson, M. Carretero, P. K. Maini, L. L. Bonilla
Complex biological processes involve collective behavior of entities (bacteria, cells, animals) over many length and time scales and can be described by discrete models that track individuals or by continuum models involving densities and fields. We consider hybrid stochastic agent-based models of branching morphogenesis and angiogenesis (new blood vessel creation from preexisting vasculature), which treat cells as individuals that are guided by underlying continuous chemical and/or mechanical fields. In these descriptions, leader (tip) cells emerge from existing branches and follower (stalk) cells build the new sprout in their wake. Vessel branching and fusion (anastomosis) occur as a result of tip and stalk cell dynamics. Coarse graining these hybrid models in appropriate limits produces continuum partial differential equations (PDEs) for endothelial cell densities that are more analytically tractable. While these models differ in nonlinearity, they produce similar equations at leading order when chemotaxis is dominant. We analyze this leading order system in a simple quasi-one-dimensional geometry and show that the numerical solution of the leading order PDE is well described by a soliton wave that evolves from vessel to source. This wave is an attractor for intermediate times until it arrives at the hypoxic region releasing the growth factor. The mathematical techniques used here thus identify common features of discrete and continuum approaches and provide insight into general biological mechanisms governing their collective dynamics.
复杂的生物过程涉及实体(细菌、细胞、动物)在许多长度和时间尺度上的集体行为,可以通过跟踪个体的离散模型或涉及密度和场的连续模型来描述。我们考虑了分支形态发生和血管生成(从先前存在的血管生成新血管)的混合随机代理模型,该模型将细胞视为个体,由潜在的连续化学和/或机械场引导。在这些描述中,领导细胞(尖端)从现有的分支中产生,跟随细胞(柄)在它们的尾迹中建立新的芽。血管分支和融合(吻合)是尖端和柄细胞动力学的结果。粗粒化这些混合模型在适当的限制下产生内皮细胞密度的连续偏微分方程(PDEs),更易于分析处理。虽然这些模型在非线性上有所不同,但当趋化性占主导地位时,它们在主导阶上产生相似的方程。我们在一个简单的准一维几何结构中分析了这个先导系统,并证明了先导系统的数值解可以很好地用从容器到源的演化孤子波来描述。在到达缺氧区释放生长因子之前,这个波在中间时间是一个吸引子。因此,这里使用的数学技术确定了离散和连续方法的共同特征,并提供了对控制其集体动力学的一般生物机制的见解。
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引用次数: 0
Extended states in one-dimensional aperiodic lattices with linearly varying patches 具有线性变化斑块的一维非周期格中的扩展态
Pub Date : 2023-11-14 DOI: 10.1103/physrevb.108.184201
Longyan Gong
We introduce a family of one-dimensional aperiodic tight-binding models with linearly varying patches of $A$-type sites with on-site energies ${ensuremath{epsilon}}_{A}=0$ connected by single $B$-type sites with ${ensuremath{epsilon}}_{B}=W$. We analytically show such structures have strong spatial correlations. We theoretically find states are extended at resonance levels in the vicinity of ${E}_{M}^{ensuremath{kappa}}=ensuremath{-}2cosfrac{ensuremath{kappa}ensuremath{pi}}{M}$ if they are allowed energies, where $M=md$ are the size differences of patches, $d$ is the variation rate of patch sizes, $mensuremath{in}{mathcal{N}}_{+}$, and $ensuremath{kappa}=1,2,...,Mensuremath{-}1$. Related delocalization-localization transitions are explored. Numerical evidence is in excellent quantitative agreement with theoretical predictions.
我们引入了一类一维非周期紧密结合模型,这些模型具有线性变化的$A$型位点斑块,位点能量为${ensuremath{epsilon}}_{A}=0$,由单个$B$型位点与${ensuremath{epsilon}}_{B}=W$连接。我们分析表明,这种结构具有很强的空间相关性。理论上,我们发现状态在${E}_{M}^{ensuremath{kappa}}=ensuremath{-}2cosfrac{ensuremath{kappa}ensuremath{pi}}{M}$附近的共振能级上扩展,如果它们是允许的能量,其中$M=md$是斑块的大小差异,$d$是斑块大小的变化率,$mensuremath{in}{mathcal{N}}_{+}$和$ensuremath{kappa}=1,2,...,Mensuremath{-}1$。探讨了相关的离域-定位转换。数值证据与理论预测在数量上非常一致。
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引用次数: 0
Nonequilibrium steady states in coupled asymmetric and symmetric exclusion processes 耦合不对称和对称不相容过程中的非平衡态
Pub Date : 2023-11-14 DOI: 10.1103/physreve.108.054122
Atri Goswami, Utsa Dey, Sudip Mukherjee
We propose and study a one-dimensional (1D) model consisting of two lanes with open boundaries. One of the lanes executes diffusive and the other lane driven unidirectional or asymmetric exclusion dynamics, which are mutually coupled through particle exchanges in the bulk. We elucidate the generic nonuniform steady states in this model. We show that in a parameter regime, where hopping along the TASEP lane, diffusion along the SEP lane, and the exchange of particles between the TASEP and SEP lanes compete, the SEP diffusivity $D$ appears as a tuning parameter for both the SEP and TASEP densities for a given exchange rate in the nonequilibrium steady states of this model. Indeed, $D$ can be tuned to achieve phase coexistence in the asymmetric exclusion dynamics together with spatially smoothly varying density in the diffusive dynamics in the steady state. We obtain phase diagrams of the model using mean field theories, and corroborate and complement the results with stochastic Monte Carlo simulations. This model reduces to an isolated open totally asymmetric exclusion process (TASEP) and an open TASEP with bulk particle nonconserving Langmuir kinetics (LK), respectively, in the limits of vanishing and diverging particle diffusivity in the lane executing diffusive dynamics. Thus, this model works as an overarching general model, connecting both pure TASEPs and TASEPs with LK in different asymptotic limits. We further define phases in the SEP and obtain phase diagrams and show their correspondence with the TASEP phases. In addition to its significance as a 1D driven, diffusive model, this model also serves as a simple reduced model for cell biological transport by molecular motors undergoing diffusive and directed motion inside eukaryotic cells.
我们提出并研究了一个由开放边界的两车道组成的一维(1D)模型。其中一条通道执行扩散动力学,另一条通道驱动单向或不对称排斥动力学,它们通过体内粒子交换相互耦合。我们阐明了该模型的一般非均匀稳态。我们证明了在一个参数体系中,沿着TASEP通道跳跃,沿着SEP通道扩散,以及在TASEP和SEP通道之间的粒子交换竞争,在该模型的非平衡稳态中,给定交换率下,SEP扩散率$D$作为SEP和TASEP密度的调谐参数出现。事实上,在非对称不相容动力学中,通过调整D可以实现相共存,同时在稳态扩散动力学中,可以实现密度的空间平滑变化。我们利用平均场理论得到了模型的相图,并用随机蒙特卡罗模拟对结果进行了证实和补充。在执行扩散动力学的通道中,在粒子扩散率消失和发散的极限下,该模型分别简化为孤立的开放的完全不对称不相容过程(TASEP)和具有体粒子非守恒朗缪尔动力学(LK)的开放TASEP。因此,该模型作为一个总体的一般模型,将纯tasep和具有LK的tasep在不同的渐近极限下连接起来。我们进一步定义了SEP中的相,得到了相图,并显示了它们与TASEP相的对应关系。除了作为一维驱动的扩散模型的意义外,该模型还可以作为真核细胞内分子马达进行扩散和定向运动的细胞生物运输的简单简化模型。
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引用次数: 0
Generalized dynamical theories in phase space and the hydrogen atom 相空间与氢原子的广义动力学理论
Pub Date : 2023-11-14 DOI: 10.1103/physreva.108.052212
Martin Plávala, Matthias Kleinmann
We show that the phase-space formulation of general probabilistic theories can be extended to include a generalized time evolution and that it can describe a nonquantum hydrogenlike system which is stable, has discrete energy levels, and includes the Zeeman effect. This allows us to study dynamical effects such as excitations of the hydrogenlike system by a resonant laser and Rutherford scattering. Our construction demonstrates that classical theory and quantum theory can be seen as specific choices of general probabilistic theory in phase space and that other probabilistic theories also lead to measurable predictions.
我们证明了一般概率理论的相空间公式可以扩展到包括广义时间演化,并且它可以描述一个稳定的、具有离散能级的、包含塞曼效应的非量子类氢系统。这使我们能够研究动力学效应,如共振激光和卢瑟福散射对类氢体系的激发。我们的构建表明,经典理论和量子理论可以被看作是相空间中一般概率理论的具体选择,其他概率理论也可以导致可测量的预测。
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引用次数: 2
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