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Dissector-Assisted Liposuction for Dorsocervical Fibrolipodystrophy (Buffalo Hump): Results from 57 Patients. 解剖辅助吸脂治疗颈背纤维脂肪营养不良(Buffalo驼峰):57例患者的结果。
IF 3.4 2区 医学 Q1 SURGERY Pub Date : 2026-02-01 Epub Date: 2025-05-20 DOI: 10.1097/PRS.0000000000012212
Shaoluan Zheng, Liqun Teng, Xiangren Wang, Fei Yang, Xichao He, Shunli Yeoh, Fazhi Qi, Jiaqi Liu

Background: Buffalo hump is fibrolipodystrophy in the posterior part of neck. Although established surgical treatments, such as lipectomy and liposuction, are available, they each have notable limitations. Lipectomy often leads to significant scarring, trauma, and prolonged recovery. Traditional liposuction encounters challenges such as high suction resistance and potential complications. The objective of this study is to introduce a novel technique-dissector-assisted liposuction-as a potential solution to address these limitations.

Methods: A case series study was conducted. The fibrous tissue was first dissected using a specialized dissector to reduce the resistance in the subcutaneous and deep fascia layers. The fibers within the buffalo hump were also carefully dissected. Once the resistance in the buffalo hump area was significantly reduced, a 3.5-mm harvesting cannula with a cutting edge was used to perform liposuction. A 5-point Likert scale was used to assess outcomes preoperatively and 6 months postoperatively.

Results: A total of 57 patients underwent dissector-assisted liposuction for buffalo hump treatment without complications. The average volume of the buffalo hump was 328.72 mL. Immediate improvements in appearance were observed in all patients. Six months after surgery, with the exception of scarring (which showed a median Likert scale value of 0 in both the preoperative and postoperative periods), the Likert scale value for the other 4 parameters showed a significant increase ( P < 0.05).

Conclusions: Dissector-assisted liposuction offers several advantages, including the predissecting of fibrous tissue, reduction of fibrous tissue volume, and decreased resistance during liposuction, making it a promising approach for treating buffalo hump.

背景:水牛驼峰是颈部后部的纤维脂肪营养不良。虽然现有的手术治疗,如脂肪切除术和吸脂术,都是可行的,但它们都有明显的局限性。唇部切除术通常会导致明显的疤痕、创伤和长时间的恢复。传统的吸脂术面临着高吸阻和潜在并发症等挑战。本研究的目的是介绍一种新的技术,解剖辅助吸脂,作为解决这些局限性的潜在解决方案。方法:采用病例系列研究。首先使用专门的解剖器解剖纤维组织,以减少皮下和深筋膜层的阻力。水牛驼峰内的纤维也被仔细解剖。一旦水牛驼峰区域的阻力显著降低,就使用3.5毫米的割边套管进行抽脂。采用5分Likert量表评估术前和术后6个月的预后。结果:共有57例患者接受了解剖辅助吸脂治疗水牛驼峰,无并发症。水牛驼峰的平均体积为328.72 mL。所有患者的外观都得到了立即的改善。术后6个月,除瘢痕形成(术前和术后LS中位数均为0)外,其他4个参数的LS均显著增加(p结论:解剖辅助吸脂术具有纤维组织预剥离、纤维组织体积减小、吸脂过程阻力降低等优点,是治疗水牛驼峰的一种很有前景的方法。
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引用次数: 0
Modiolus-Based Dynamic Reconstruction for Transverse Facial Cleft: A Retrospective Cohort Study. 基于modololus的横向面部唇裂动态重建:回顾性队列研究。
IF 3.4 2区 医学 Q1 SURGERY Pub Date : 2026-01-26 DOI: 10.1097/PRS.0000000000012853
Xinwei Cheng, Jin Zhang, Jian Wang, Jia Zhou

Background: Transverse facial cleft is a rare congenital craniofacial anomaly that significantly impacts both aesthetic appearance and functional integrity of the oral commissure. Current surgical techniques demonstrate suboptimal efficacy in restoring commissural morphology and facial symmetry. To further optimize surgical outcomes, we enhanced the conventional approach by incorporating anatomical reconstruction of the modiolus and orbicularis oris, and evaluated its long-term aesthetic outcomes in the symmetry of commissure compared with conventional methods.

Methods: This single-center cohort study retrospectively analyzed 20 patients who underwent unilateral transverse facial cleft repair between May 2015 and October 2023. The cohort comprised two groups: (1) conventional repair group (n=9) and (2) priority modiolus reconstruction group (n=11). Objective anthropometric measurements were obtained at preoperative, immediate postoperative, and long-term follow-up stages. Subjective evaluations were performed using Face-Q and Visual Analog Scale (VAS) questionnaires.

Results: Immediate postoperative assessment revealed significant improvement in the lower cheilion spread angle (ΔLCSA) in the modiolus reconstruction group compared to controls (8.22 ± 5.43 vs. 3.67 ± 2.99, p = 0.045). Long-term follow-up demonstrated significant differences in four key perioral measurements: ΔUCSA (10.04 ± 6.83 vs. 4.56 ± 1.78, p = 0.046), ΔLCSA (9.47 ± 5.19 vs. 3.94 ± 2.78, p = 0.014), ΔLs-Ch (9.75 ± 5.91 vs. 3.82 ± 1.95, p = 0.004) and Δl-Ch (10.59 ± 5.41 vs. 3.89 ± 3.32, p = 0.006), indicating enhanced commissural symmetry, particularly during mouth-opening. Professional evaluation using VAS for commissural symmetry were also significantly higher in the reconstruction group at long-term follow-up (7.78 ± 0.75 vs. 8.45 ± 0.58, p = 0.042).

Conclusions: In patients with unilateral transverse facial cleft, priority modiolus reconstruction is associated with superior static and dynamic symmetry of commissure compared with conventional repair, with maintained long-term outcomes.

背景:横向面裂是一种罕见的先天性颅面畸形,严重影响口腔连接的美观和功能完整性。目前的外科技术在恢复关节形态和面部对称性方面的效果并不理想。为了进一步优化手术效果,我们对常规入路进行了改进,结合了口轮匝肌的解剖重建,并与常规入路比较了其在连合对称性方面的长期美学效果。方法:本单中心队列研究回顾性分析了2015年5月至2023年10月期间接受单侧横切面裂修复术的20例患者。该队列分为两组:(1)常规修复组(n=9)和(2)优先修复组(n=11)。在术前、术后即刻和长期随访阶段获得客观的人体测量数据。采用Face-Q和视觉模拟量表(VAS)进行主观评价。结果:术后立即评估显示,与对照组相比,小尺骨重建组的下尺骨伸展角(ΔLCSA)有显著改善(8.22±5.43比3.67±2.99,p = 0.045)。长期随访显示,四项关键的口周测量值ΔUCSA(10.04±6.83 vs. 4.56±1.78,p = 0.046)、ΔLCSA(9.47±5.19 vs. 3.94±2.78,p = 0.014)、ΔLs-Ch(9.75±5.91 vs. 3.82±1.95,p = 0.004)和Δl-Ch(10.59±5.41 vs. 3.89±3.32,p = 0.006)均有显著差异,表明关节对称性增强,特别是在张嘴时。长期随访时,重建组的联合关节对称性专业评分(VAS)也显著高于重建组(7.78±0.75比8.45±0.58,p = 0.042)。结论:在单侧面部横裂患者中,与常规修复相比,优先重建小梁与更好的连接静态和动态对称性相关,并保持长期疗效。
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引用次数: 0
LETTER TO THE EDITOR: Over 10 Years' Follow-Up Experience after Inverted-T Superior Pedicle Breast Reduction with the Modified Ribeiro Flap. 致编辑的信:改良Ribeiro皮瓣逆行t型上蒂乳房缩窄术后超过10年的随访经验。
IF 3.4 2区 医学 Q1 SURGERY Pub Date : 2026-01-26 DOI: 10.1097/PRS.0000000000012850
Eric Swanson
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引用次数: 0
Mandibular Distraction Osteogenesis for Pierre Robin Sequence in Early Infancy: A Systematic Review. 早期婴儿期Pierre Robin序列下颌牵张成骨:系统回顾。
IF 3.4 2区 医学 Q1 SURGERY Pub Date : 2026-01-26 DOI: 10.1097/PRS.0000000000012852
Ryan W Dominguez, Alexander E Velazquez, Trey Cinclair, Cynthia S Wang, Alex A Kane, Paymon Sanati-Mehrizy

Background: Pierre Robin Sequence (PRS) is defined by micrognathia, glossoptosis, and upper airway obstruction. Although neonatal management is well established, surgical indications and protocols beyond this period remain variable due to the absence of standardized guidelines. This review evaluates published treatment algorithms for mandibular distraction osteogenesis (MDO), identifies common decision-making criteria, and proposes a unifying algorithm informed by existing literature. We hypothesize that MDO is preferred following failed conservative management of feeding and airway function.

Methods: A literature search was conducted following PRISMA guidelines. Inclusion criteria required studies to describe treatment algorithms, decision-making criteria, or institutional protocols for MDO. Of 275 studies identified, 23 met inclusion criteria.

Results: Airway management strategies prioritized non-invasive approaches, including prone/lateral positioning, supplemental oxygen, positive airway pressure, and nasopharyngeal airway (NPA) use. Polysomnography (PSG) was utilized in 12 studies to guide decision-making, with an Apnea-Hypopnea Index (AHI) > 20 frequently cited as the threshold for surgical escalation. 16 studies favored MDO over tongue-lip adhesion (TLA) due to its lower risk of long-term tracheostomy and feeding impairment, though three studies preferred TLA, and four did not specify a preferred approach. The earliest reported MDO occurred at 11 days; however, the mean age across studies was 100 days, indicating most interventions occurred in early infancy beyond the neonatal period (<28 days).

Conclusions: Algorithm-based airway management in PRS emphasizes early PSG assessment, conservative trialing, and MDO as the preferred surgical intervention. Further studies should refine predictive criteria for MDO success and optimize management strategies beyond the neonatal period.

背景:皮埃尔·罗宾综合征(Pierre Robin Sequence, PRS)被定义为小颌畸形、舌光下垂和上气道阻塞。虽然新生儿管理已经建立,但由于缺乏标准化的指导方针,这一时期以后的手术指征和手术方案仍然多变。本综述评估了已发表的下颌牵张成骨(MDO)的治疗算法,确定了共同的决策标准,并根据现有文献提出了一个统一的算法。我们假设在进食和气道功能保守管理失败后,MDO是首选。方法:按照PRISMA指南进行文献检索。纳入标准要求研究描述治疗算法、决策标准或MDO的机构方案。在确定的275项研究中,有23项符合纳入标准。结果:气道管理策略优先考虑非侵入性入路,包括俯卧位/侧卧位、补充氧气、气道正压通气和鼻咽气道(NPA)的使用。12项研究使用多导睡眠图(PSG)来指导决策,呼吸暂停低通气指数(AHI) bb20经常被引用为手术升级的阈值。16项研究倾向于MDO而不是舌唇粘连(TLA),因为其长期气管切开术和喂养障碍的风险较低,尽管有3项研究倾向于TLA, 4项研究没有指定首选方法。最早报道的MDO发生在第11天;然而,所有研究的平均年龄为100天,这表明大多数干预措施发生在婴儿早期,超过新生儿期(结论:基于算法的PRS气道管理强调早期PSG评估,保守试验和MDO是首选的手术干预措施。进一步的研究应该完善MDO成功的预测标准,并优化新生儿期后的管理策略。
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引用次数: 0
Evaluation of the BREAST-II Trial for Total Breast Reconstruction Solely Using Autologous Fat Transfer: 1-Year Follow-Up. 单独使用自体脂肪移植进行全乳房重建的Breast - ii试验评价:1年随访。
IF 3.4 2区 医学 Q1 SURGERY Pub Date : 2026-01-22 DOI: 10.1097/PRS.0000000000012742
Wessel B W van der Venne, Kyrah S Goeree, Jamilla L M Wederfoort, Juliëtte E Hommes, Sander M J van Kuijk, Esther M Heuts, Andrzej A Piatkowski de Grzymala, Chantal M Mouës

Background: Autologous Fat Transfer (AFT) has emerged as a promising technique for total breast reconstruction post-mastectomy, particularly in patients unsuitable for other reconstruction methods. Evaluating its efficacy, safety, and impact on quality of life is essential.

Objective: To assess the efficacy and safety outcomes of AFT as total breast reconstruction in women post-mastectomy, based on 12-month follow-up data from the BREAST-II trial.

Methods: This multicentre, nonrandomised clinical trial included women aged ≥18 years with a history of or planned mastectomy across eight Dutch hospitals. Participants underwent multiple AFT sessions combined with external expansion using the EVE-bra device, with a maximum of five sessions over 12 months. Primary outcome was quality of life measured by BREAST-Q and BODY-Q questionnaires. Secondary outcomes included safety (serious adverse events [SAEs]), operating time, hospital stay, and number of sessions.

Results: A total of 229 women were included. At 12 months post-AFT, significant improvements were observed in psychosocial well-being (+5.72 ±16.79), sexual well-being (+8.05 ±19.61), physical well-being of the chest (+5.97 ±20.44), and chest satisfaction (+17.22 ±27.27) (all p<0.001). BODY-Q scores showed significant increases in satisfaction with abdomen, back, body, hips/outer thighs, inner thighs, and scars (all p<0.001). Among 805 AFT sessions, 52 (S)AEs occurred (6.46% complication rate). Hospital stays were less than one day per session.

Conclusions: AFT is an effective and safe total breast reconstruction technique post-mastectomy, significantly improving quality of life with low complication rates. These findings support AFT as a valuable addition to breast reconstruction options.

Trial registration: AFT: Introduction of a Full Breast Reconstructive Method (BREAST-II).

Clinicaltrialsgov id: NCT04261829.

Study details aft: Introduction of a Full Breast Reconstructive Method | ClinicalTrials.gov.

背景:自体脂肪移植(AFT)已成为乳房切除术后全乳房重建的一种很有前途的技术,特别是在不适合其他重建方法的患者中。评估其有效性、安全性和对生活质量的影响是至关重要的。目的:基于breast - ii试验的12个月随访数据,评估AFT作为乳房切除术后女性全乳房重建的疗效和安全性。方法:这项多中心、非随机临床试验纳入了来自荷兰8家医院年龄≥18岁、有乳房切除术史或计划切除的女性。参与者接受了多次AFT治疗并使用EVE-bra装置进行外部扩张,在12个月内最多进行了5次治疗。主要结局是通过BREAST-Q和BODY-Q问卷测量生活质量。次要结局包括安全性(严重不良事件[sae])、手术时间、住院时间和疗程数。结果:共纳入229名女性。术后12个月,患者心理社会健康(+5.72±16.79)、性健康(+8.05±19.61)、胸部生理健康(+5.97±20.44)、胸部满意度(+17.22±27.27)均有显著改善。结论:术后全乳房重建技术有效、安全,可显著改善患者生活质量,并发症发生率低。这些发现支持AFT作为乳房重建选择的一个有价值的补充。试验注册:AFT:引入全乳房重建方法(Breast - ii)。clinicaltrialgov编号:NCT04261829。研究详情见:全面乳房重建方法的介绍b|临床试验网站。
{"title":"Evaluation of the BREAST-II Trial for Total Breast Reconstruction Solely Using Autologous Fat Transfer: 1-Year Follow-Up.","authors":"Wessel B W van der Venne, Kyrah S Goeree, Jamilla L M Wederfoort, Juliëtte E Hommes, Sander M J van Kuijk, Esther M Heuts, Andrzej A Piatkowski de Grzymala, Chantal M Mouës","doi":"10.1097/PRS.0000000000012742","DOIUrl":"https://doi.org/10.1097/PRS.0000000000012742","url":null,"abstract":"<p><strong>Background: </strong>Autologous Fat Transfer (AFT) has emerged as a promising technique for total breast reconstruction post-mastectomy, particularly in patients unsuitable for other reconstruction methods. Evaluating its efficacy, safety, and impact on quality of life is essential.</p><p><strong>Objective: </strong>To assess the efficacy and safety outcomes of AFT as total breast reconstruction in women post-mastectomy, based on 12-month follow-up data from the BREAST-II trial.</p><p><strong>Methods: </strong>This multicentre, nonrandomised clinical trial included women aged ≥18 years with a history of or planned mastectomy across eight Dutch hospitals. Participants underwent multiple AFT sessions combined with external expansion using the EVE-bra device, with a maximum of five sessions over 12 months. Primary outcome was quality of life measured by BREAST-Q and BODY-Q questionnaires. Secondary outcomes included safety (serious adverse events [SAEs]), operating time, hospital stay, and number of sessions.</p><p><strong>Results: </strong>A total of 229 women were included. At 12 months post-AFT, significant improvements were observed in psychosocial well-being (+5.72 ±16.79), sexual well-being (+8.05 ±19.61), physical well-being of the chest (+5.97 ±20.44), and chest satisfaction (+17.22 ±27.27) (all p<0.001). BODY-Q scores showed significant increases in satisfaction with abdomen, back, body, hips/outer thighs, inner thighs, and scars (all p<0.001). Among 805 AFT sessions, 52 (S)AEs occurred (6.46% complication rate). Hospital stays were less than one day per session.</p><p><strong>Conclusions: </strong>AFT is an effective and safe total breast reconstruction technique post-mastectomy, significantly improving quality of life with low complication rates. These findings support AFT as a valuable addition to breast reconstruction options.</p><p><strong>Trial registration: </strong>AFT: Introduction of a Full Breast Reconstructive Method (BREAST-II).</p><p><strong>Clinicaltrialsgov id: </strong>NCT04261829.</p><p><strong>Study details aft: </strong>Introduction of a Full Breast Reconstructive Method | ClinicalTrials.gov.</p>","PeriodicalId":20128,"journal":{"name":"Plastic and reconstructive surgery","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146019259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Impact of Aesthetic Osseous Genioplasty on Upper Airway Volumes - A Single Center Retrospective Cohort Study. 美学骨缺损成形术对上气道容积的影响-单中心回顾性队列研究。
IF 3.4 2区 医学 Q1 SURGERY Pub Date : 2026-01-22 DOI: 10.1097/PRS.0000000000012849
Martin Kauke-Navarro, Victoria Kong, Paula Flores-Pérez, Albert L Rancu, Fortunay Diatta, Emily Parker, Felix J Klimitz, Omar Allam, Ali-Farid Safi, Michael Alperovich

Background: The effect of aesthetic osseous genioplasty on upper airway volume remains unclear, particularly the relative contributions of horizontal and vertical chin changes.

Methods: We retrospectively analyzed volumetric airway changes in 70 patients who underwent osseous genioplasty, using pre- and postoperative craniofacial CT scans (140 total). Image segmentation was performed to approximate volumes of the nasopharynx, oropharynx, hypopharynx, and total pharynx. Horizontal chin projection change was defined as the difference in anterior-posterior (AP) position of the osteotomized chin segment, and vertical change as lengthening or shortening based on inferior-superior movement of the pogonion, both measured between pre- and postoperative scans. Univariable and multivariable linear regressions were then performed to assess associations with airway volume change.

Results: Vertical chin lengthening was independently associated with oropharyngeal (β = 664.4 mm³, p = 0.015) and total airway volume (β = 917.6 mm³, p = 0.011) change, confirmed in univariable models (oropharynx: β = 728.0 mm³, p = 0.0047). Horizontal projection showed no significant associations across any airway region. Across the entire cohort, patients experienced net reductions in airway volume postoperatively, most notably in the oropharynx (-1270 mm³, p = 0.048) and total airway (-2801 mm³, p = 0.0016), particularly in cases with vertical chin shortening. Controls demonstrated minimal change. These findings suggest that vertical lengthening may increase airway patency, while vertical reduction may contribute to narrowing.

Conclusion: Vertical movement of the osteotomized chin segment, both lengthening and shortening, was identified as a significant factor associated with postoperative airway change after genioplasty. This highlights the relevance of vertical repositioning in surgical planning and provides a basis for future studies on the functional effects of aesthetic genioplasty on the airway.

背景:审美性骨颏成形术对上气道容积的影响尚不清楚,特别是水平和垂直下巴变化的相对贡献。方法:我们回顾性分析70例骨性颏成形术患者的气道容积变化,使用术前和术后颅面CT扫描(共140例)。进行图像分割以近似鼻咽、口咽、下咽和总咽的体积。水平下巴投影变化定义为截骨颏段前后(AP)位置的差异,垂直变化定义为根据毒瘤的上下运动而延长或缩短,均在术前和术后扫描之间测量。然后进行单变量和多变量线性回归来评估与气道容积变化的关系。结果:垂直下巴延长是独立与口咽(β = 664.4毫米 ³ = 0.015页)和总气道体积(β ³= 917.6毫米,0.011 p = )变化,证实了在单变量模型(口咽:β = 728.0毫米 ³ = 0.0047页)。水平投影显示任何气道区域无显著关联。在整个队列中,患者术后气道体积净减少,最明显的是口咽部(-1270 mm³,p = 0.048)和总气道(-2801 mm³,p = 0.0016),特别是垂直下巴缩短的病例。控制组的变化最小。这些发现提示垂直延长可能增加气道通畅,而垂直缩小可能导致气道狭窄。结论:截骨颏段的垂直运动,包括延长和缩短,被认为是颏成形术后气道改变的重要因素。这突出了垂直重新定位在手术计划中的相关性,并为未来研究美学颏部成形术对气道的功能影响提供了基础。
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引用次数: 0
Smooth Implant Stability in Inframammary Approach Augmentation: The Modified Bi-Muscular Flap Technique VS. Dual-Plane with Fixation Suture. 乳下入路增强术中种植体的平滑稳定性:改良双肌瓣技术与双平面固定缝合技术。
IF 3.4 2区 医学 Q1 SURGERY Pub Date : 2026-01-22 DOI: 10.1097/PRS.0000000000012838
Zenan Xia, Jiangmiao Xie, Runqing Su, Ang Zeng, Xiao Long

Amid the global trend toward smooth implants' use, implant stability has become a progressively significant concern for augmentation mammaplasty. During the dual-plane augmentation via the inframammary fold (IMF) approach, IMF fixation suture-suturing the Scarpa's fascia to the deep fascia-is routinely adopted by surgeons to minimize inferior implant displacement. However, this approach of maintaining implant stability demonstrates inconsistent reliability, particularly with smooth implants. Excluding suboptimal technical factors, the fundamental cause of implant malposition lies in inadequate inferior or lateral support structure. Based on pectoralis major's anatomical foundation and the access characteristics of the IMF incision, the authors introduce an innovative technical refinement-the modified bi-muscular flap (BMF) technique. The procedure involves an L-shaped muscle release that preserves the lateral long-head origins of the muscle, creating an inferior support structure for the implant. A preliminary outcome compared with the dual-plane technique using fixation suture suggests that this new technique may represent a promising alternative for reducing smooth implant malposition and improving long-term stability.

在全球趋向于使用光滑的植入物的趋势中,植入物的稳定性已逐渐成为隆胸成形术的重要关注点。在通过乳房下襞(IMF)入路进行双平面隆胸时,外科医生通常采用IMF固定缝合线(将斯卡帕筋膜缝合到深筋膜上)来减少下假体移位。然而,这种维持种植体稳定性的方法表现出不稳定的可靠性,特别是对于光滑的种植体。排除不理想的技术因素,导致种植体错位的根本原因是下位或侧位支撑结构不充分。基于胸大肌的解剖基础和IMF切口的入路特点,作者介绍了一种创新的技术改进——改良双肌瓣(BMF)技术。该手术包括l型肌肉释放,保留了肌肉的外侧长头起源,为植入物创造了一个下支撑结构。与使用固定缝线的双平面技术相比,初步结果表明,这种新技术可能是减少平滑种植体错位和提高长期稳定性的有希望的替代方法。
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引用次数: 0
An Analysis of the Timing of Autologous Breast Reconstruction After Mastectomy and Radiotherapy. 乳房切除术和放疗后自体乳房重建时机的分析。
IF 3.4 2区 医学 Q1 SURGERY Pub Date : 2026-01-22 DOI: 10.1097/PRS.0000000000012841
Aaron I Dadzie, Aubree Rossman, Katie Hansen, Madison Gardner, Sydney Somers, Catie Bautista, Joanna Chen, Devin Eddington, Jay Agarwal, Alvin Kwok

Introduction: Autologous breast reconstruction (ABR) following postmastectomy radiotherapy (PMRT) is often delayed several months due to adverse effects of radiation on outcomes. The optimal time between PMRT and ABR remains uncertain. We sought to analyze how the timing of ABR following PMRT affects postoperative outcomes.

Methods: A retrospective analysis was performed on adult female patients who underwent ABR. Cases were analyzed on a per-flap basis and were stratified into PMRT and non-PMRT groups. The PMRT group was further stratified into cohorts based on the time from completion of PMRT to ABR defined as: 0-3 months, 3-6 months, 6-12 months, and 12+ months. Primary outcomes included flap failure or necrosis and immediate reoperation. All other complications were secondary outcomes. Group differences were assessed using Chi-squared, Fischer's exact, Kruskal-Wallis and Wilcoxon rank sum tests. A logistic mixed-effects model was conducted to identify variables associated with postoperative complications.

Results: 514 flaps among 339 patients were included. 37.2% of the flaps were performed following PMRT: 5 within 0-3 months, 72 within 3-6 months, 71 within 6-12 months, and 43 within 12+ months. There were no statistically significant differences in reoperations, flap thrombosis, flap failure, infection, wound dehiscence, or operative time when comparing cases with or without PMRT and no statistically significant differences when comparing cases at the various time intervals.

Conclusion: No statistically significant differences in postoperative complications were observed across PMRT timing intervals. These findings do not support a strong association between the interval from radiotherapy to ABR and complication rates.

导言:乳房切除术后放疗(PMRT)后的自体乳房重建(ABR)通常由于放疗对结果的不良影响而延迟几个月。PMRT和ABR之间的最佳时间仍然不确定。我们试图分析PMRT后ABR的时机如何影响术后结果。方法:对接受ABR的成年女性患者进行回顾性分析。病例按皮瓣进行分析,并分为PMRT组和非PMRT组。PMRT组根据完成PMRT至ABR的时间进一步分层,定义为:0-3个月、3-6个月、6-12个月和12+个月。主要结果包括皮瓣失败或坏死和立即再手术。其他并发症均为次要结果。采用卡方检验、Fischer’s exact检验、Kruskal-Wallis检验和Wilcoxon秩和检验评估组间差异。采用logistic混合效应模型确定与术后并发症相关的变量。结果:339例患者共514个皮瓣。37.2%的皮瓣在PMRT后完成:0-3个月5例,3-6个月72例,6-12个月71例,12+个月43例。PMRT前后再手术、皮瓣血栓形成、皮瓣失效、感染、创面裂开、手术时间的差异无统计学意义,各时间间隔的差异无统计学意义。结论:不同PMRT时间间隔术后并发症发生率无统计学差异。这些发现不支持放疗至ABR的间隔时间与并发症发生率之间的强相关性。
{"title":"An Analysis of the Timing of Autologous Breast Reconstruction After Mastectomy and Radiotherapy.","authors":"Aaron I Dadzie, Aubree Rossman, Katie Hansen, Madison Gardner, Sydney Somers, Catie Bautista, Joanna Chen, Devin Eddington, Jay Agarwal, Alvin Kwok","doi":"10.1097/PRS.0000000000012841","DOIUrl":"https://doi.org/10.1097/PRS.0000000000012841","url":null,"abstract":"<p><strong>Introduction: </strong>Autologous breast reconstruction (ABR) following postmastectomy radiotherapy (PMRT) is often delayed several months due to adverse effects of radiation on outcomes. The optimal time between PMRT and ABR remains uncertain. We sought to analyze how the timing of ABR following PMRT affects postoperative outcomes.</p><p><strong>Methods: </strong>A retrospective analysis was performed on adult female patients who underwent ABR. Cases were analyzed on a per-flap basis and were stratified into PMRT and non-PMRT groups. The PMRT group was further stratified into cohorts based on the time from completion of PMRT to ABR defined as: 0-3 months, 3-6 months, 6-12 months, and 12+ months. Primary outcomes included flap failure or necrosis and immediate reoperation. All other complications were secondary outcomes. Group differences were assessed using Chi-squared, Fischer's exact, Kruskal-Wallis and Wilcoxon rank sum tests. A logistic mixed-effects model was conducted to identify variables associated with postoperative complications.</p><p><strong>Results: </strong>514 flaps among 339 patients were included. 37.2% of the flaps were performed following PMRT: 5 within 0-3 months, 72 within 3-6 months, 71 within 6-12 months, and 43 within 12+ months. There were no statistically significant differences in reoperations, flap thrombosis, flap failure, infection, wound dehiscence, or operative time when comparing cases with or without PMRT and no statistically significant differences when comparing cases at the various time intervals.</p><p><strong>Conclusion: </strong>No statistically significant differences in postoperative complications were observed across PMRT timing intervals. These findings do not support a strong association between the interval from radiotherapy to ABR and complication rates.</p>","PeriodicalId":20128,"journal":{"name":"Plastic and reconstructive surgery","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146019248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Arrow Palatoplasty: A Novel Technique for Soft Palate Revision in Patients with Velopharyngeal Insufficiency and a Large Pharyngeal Gap. 箭形腭成形术:一种用于腭咽功能不全和咽间隙大的患者软腭翻修的新技术。
IF 3.4 2区 医学 Q1 SURGERY Pub Date : 2026-01-22 DOI: 10.1097/PRS.0000000000012837
Kshipra Hemal, Natalie M Plana, Margaret Lico, Rami Kantar, Rebecca Lisk, Augustus Parker, Roberto L Flores

Clinical question/level of evidence: Therapeutic, IV.

临床问题/证据水平:治疗性,IV。
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引用次数: 0
Neurocognitive and behavioral outcomes in metopic synostosis: relation to severity and surgical timing. 异位性关节闭锁的神经认知和行为结果:与严重程度和手术时机的关系。
IF 3.4 2区 医学 Q1 SURGERY Pub Date : 2026-01-22 DOI: 10.1097/PRS.0000000000012842
Pauline A E Tio, Merel J A van Staalduinen, Karolijn Dulfer, Marie-Lise C van Veelen, Mieke M Pleumeekers, Irene M J Mathijssen, Jolanda M E Okkerse

Background: Developmental and behavioral issues are frequently reported in patients with metopic synostosis. The effect of pre-operative severity and surgical timing on these outcomes remains debated and inconclusive. This study aims to describe neurocognitive profiles in patients with metopic synostosis and evaluate associations with pre-operative severity and surgical timing.

Methods: A retrospective study was conducted on patients with non-syndromic metopic synostosis who underwent fronto-orbital advancement (FOA) at Sophia Children's Hospital. Patients were born between 2006-2018 and had a minimum 6-year follow-up. Data from psychological/psychiatric diagnostic assessments were collected, including WPPSI and WISC. Pre-operative severity was determined using CranioRate.

Results: A total of 228 patients with non-syndromic metopic synostosis who underwent FOA (median age 10 months, IQR 8-12) were included. Among these, 48.2% had reported parental concerns regarding their child's developmental and behavioral functioning. In total, 99 patients underwent psychological/psychiatric assessment, of which 73 patients underwent assessment at our center at the mean age of 7.8 years. Among referred patients, full scale IQ (FSIQ) (mean 95.5, p 0.012) and processing speed index (mean 94.3, p 0.002) were significantly lower compared to normative means. No significant association was found between FSIQ and pre-operative severity or surgical timing. Among all patients who underwent assessment, 43 were diagnosed with attention deficit/hyperactivity disorder and 13 were diagnosed with autism spectrum disorder, representing 18.9% and 5.7% of the total cohort respectively.

Conclusion: In this single-center cohort, cognitive and behavioral outcomes in children with metopic synostosis are not associated with pre-operative severity or surgical timing. However, parental concerns are common, and the increased prevalence of behavioral problems in this population highlights the importance of long-term neurodevelopmental monitoring.

背景:异位性骨膜闭锁患者的发育和行为问题经常被报道。术前严重程度和手术时机对这些结果的影响仍然存在争议和不确定性。本研究旨在描述异位性关节闭锁患者的神经认知特征,并评估其与术前严重程度和手术时机的关系。方法:对索菲亚儿童医院行额眶前进术(FOA)的非综合征性异位性骨膜粘连患者进行回顾性研究。患者出生在2006年至2018年之间,并进行了至少6年的随访。收集心理/精神诊断评估的数据,包括WPPSI和WISC。术前用CranioRate测定严重程度。结果:共纳入了228例接受FOA治疗的非综合征性异位性骨膜融合患者(中位年龄10个月,IQR 8-12)。其中,48.2%的人报告父母对孩子的发育和行为功能感到担忧。共有99例患者接受了心理/精神评估,其中73例患者在我们中心接受了评估,平均年龄为7.8岁。在转诊患者中,全量表智商(FSIQ)(平均95.5,p 0.012)和处理速度指数(平均94.3,p 0.002)显著低于规范均值。未发现FSIQ与术前严重程度或手术时机有显著关联。在所有接受评估的患者中,43人被诊断为注意缺陷/多动障碍,13人被诊断为自闭症谱系障碍,分别占总队列的18.9%和5.7%。结论:在这个单中心队列研究中,异位性关节闭锁患儿的认知和行为结局与术前严重程度或手术时机无关。然而,父母的担忧是普遍的,行为问题在这一人群中越来越普遍,这凸显了长期神经发育监测的重要性。
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Plastic and reconstructive surgery
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