Yellow nail syndrome (SUA) is a little-known entity, described for the first time in 1964 in a report of 13 patients. Over time, the classic triad characterized by nail alterations, lung disease and lymphedema has been confirmed; Its diagnosis is clinical and is carried out with 2 of the 3 parameters mentioned above; the average age of presentation is 61 years. Statistically, currently, there are less than a thousand global publications with only 2 of Colombian origin. Its etiopathogenesis is still unclear because it has a very variable presentation and has also been associated with many conditions. Treatment schemes have been proposed based on case reports, which have not been compiled as a definitive management. Its prognosis according to its natural history reduces a decade of life. The objective of this article is to collect information with the help of databases to be analyzed and classified in definition, epidemiology, etiology, clinical manifestations, associated diseases, diagnosis, treatment and prognosis, to have tools to compose an adequate approach and dermatological management.
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