Psychiatrike = Psychiatriki最新文献

Type 1 diabetes (T1D) is a chronic disease characterised by insulin deficiency due to autoimmune destruction of beta-pancreatic cells. T1D, formerly known as juvenile diabetes, is the most common form of diabetes in children and adolescents. On diagnosis, parents of children with TID experience considerable stress, because they need to care for a child in a challenging and life-threatening situation that requires adherence to an intensive medical regimen, constant monitoring of, and coping with their child's condition. T1D is a complex condition that affects both children and their parents in many aspects of their daily lives. This study presents the psychometric properties of the Greek translation of the Parent Diabetes Distress Scale (PDDS), which assesses diabetes distress in parents of children with T1D. A sample of 95 parents, mainly mothers (88.4%), with a mean age of their children 12.2 years (± 3.6) and a diabetes duration of 4.7 years (± 3.4), completed the Greek translation of the PDDS. Exploratory factor analysis (EFA) revealed a five-factor model: 'Parent/child relationship distress', 'Personal distress', 'Child diabetes management distress', 'Future distress', and 'Healthcare team distress'. Confirmation Factor Analysis (CFA) confirmed the construct validity of the scale. The internal consistency indices (Cronbach alpha) for the subscales ranged from 0.69 to 0.89, while the unidimensional structure had an alpha of 0.90. Furthermore, convergent validity was shown with moderate positive correlations between the PDDS-Gr and the subscales of the DASS-21 (depression, anxiety, and stress), the child's age (in years), and the HbA1c value. Finally, parents of children with inadequate glycemic control (HbA1c ≥ 7%) presented higher scores on both the unidimensional structure and the subscales 'Parent/child relationship distress' and 'Healthcare team distress' of the PDDS-Gr. The PDDS-Gr is a valid and reliable tool for assessing diabetes distress in parents of children with T1D and can be used in both clinical and research settings.

Type 1 Diabetes mellitus (T1DM) is a chronic, multifactorial metabolic disease that requires constant medical care. T1DM is the result of an irreversible destruction of pancreatic β-cells, inevitably leading individuals to chronic exogenous insulin dependence. The prevalence of depression among T1DM is common and affects both the progression and management of the disease. The aim of this study is to present the depressive symptoms in people with T1DM who apply and those who do not apply the insulin pump therapy method and to highlight differences in terms of gender and age. The literature review was conducted using the databases PubMed, Science-Direct and Scopus. The inclusion criteria were the following: the studies had to be conducted in T1DM patients, study depressive symptomatology, the number of participants in the studies to be more than 70 people and to be in English. Initially, 464 articles were retrieved and 11 articles met the requirements for inclusion in the systematic review. The results of the systematic review, excluding paediatric patients with T1DM, showed that patients who apply the insulin pump therapy method were more likely to have higher prevalence and intensity of depressive symptoms, compared to users of multiple daily injections. Respectively, increased depressive symptoms in women with T1DM were presented, regardless of the method of treatment. Factors that mediate this difference in depressive symptoms are the sense of freedom and flexibility in lifestyle, fewer dietary restrictions, the sense of constant "bonding" and social stigma. Finally, mental health professionals should frequently evaluate the depressive symptoms of the T1DM patients, as it has a direct impact on the development and management of the disease.

Early life stressors display a high universal prevalence and constitute a major public health problem with two thirds of youth being exposed to potentially traumatic experiences by the age of 17. Traumatic stress exposure during critical periods of development may have essential and long-lasting effects on the physical and mental health of individuals and represents a developmental risk factor mediating risk for disease. Early-life stress (ELS) and childhood trauma (CT) can both have an impact on sensitive neuronal brain networks involved in stress reactions, and could exert a programming effect on glucocorticoid signaling leading to chronic hyper- or hypo-activation of the stress system. In addition, alterations in emotional and autonomic reactivity, circadian rhythm disruption, functional and structural changes in the brain, as well as immune and metabolic dysregulation have been lately identified as important risk factors for a chronically impaired homeostatic balance after ELS/CT. Furthermore, human genetic background and epigenetic modifications through stress-related gene expression could interact with these alterations and explain inter-individual variation in vulnerability or resilience to stress. This narrative review presents relevant evidence from mainly human research on the most acknowledged neurobiological allostatic pathways exerting enduring adverse effects of ELS/CT even decades later. Future studies should prospectively investigate potential confounders, their temporal sequence and combined effects at the biological level, while considering the potentially delayed time-frame for the expression of their effects. Finally, screening strategies for ELS/CT and trauma need to be improved. Information about ELS/CT history and the number of adverse experiences could help to better identify the individual risk for disease development, predict individual treatment response and design prevention strategies to reduce the negative effects of ELS/CT.

We were pleased to read Pehlivanidis and Papanikolaou's article1 and see that more colleagues are recognizing Theophrastus' text as the first description of Attention Deficit Hyperactivity Disorder (ADHD).2 We agree with the authors' perspective that Theophrastus' description may suggest the presence of more than one neurodevelopmental disorder. In fact, Theophrastus' description aligns with the shared clinical symptoms and underlying neurodevelopmental mechanisms of ADHD and Social Pragmatic Communication Disorder (SPCD). It is fascinating that a description from over 2000 years ago already presented prototypical individual transdiagnostic aspects that are compatible with a modern biological view of psychiatry. Indeed, it is not unexpected that heritable traits with clear biological underpinnings should have been perceived since the dawn of medicine. A significant leap forward in the development of this field came a few decades ago when Clements (1966)3 published a NIH-sponsored project entitled 'Minimal Brain Dysfunction in Children.' This seminal work prepared the terrain for the ongoing understanding of the grouping of signs, symptoms, and biological factors observed across various neurodevelopmental disorders. This grouping can be present in different spectrums, proportions, and nuances, including children and adults with some impairments that are not solely explained by their cognitive abilities. Thus, the characterization of 'The Obtuse Man' by Theophrastus could be considered a prototypical case of this more integrated and less fragmented view of what we call neurodevelopmental disorders.

Over the past decades mental health services around the world are faced with a high number of patients with borderline personality disorder (BPD) which has resulted in a particular emphasis on research for specialist treatments for this class of disorders. At least 5 psychotherapeutic models are based on evidence from clinical trials that support their effectiveness. In this review we present the latest research evidence as well as a summary of the basic characteristics of Transference-Focused Psychotherapy and Mentalization Based Treatment, which are not yet widely used in Greece. The two modalities originate from the psychoanalytic tradition and they have various points of convergence and divergence with regards to their structure (individual, group, combined) the role of the therapist and their use of basic theoretical concepts (eg. attachment, aggression). Their descriptive presentation in the form of a treatment manual and the standardisation of their training model, makes them accessible for training therapists and allows their introduction in psychiatric training programmes. We present a clinical case as an example of the application of the two approaches, along with the clinical and research paradigm originating from DeanCross Personality Disorder Service in London and the Centre for Understanding Personality Disorder, in order to compare the basic theoretical and technical characteristics of the two therapeutic modalities in view of their unique application within one outpatient service in the community. DeanCross provides a mixed MBT model (group, individual) with psychiatric input, which has been updated by the introduction of TFP in individual and group formats. Our review aligns with the international current that does not regard the two models in competition with each other; instead, we present a successful paradigm of their compatibility and mutual enrichment. The successful introduction of these therapies in the British public healthcare system, which is similar in its characteristics to the Greek national health system, is an encouraging prognostic factor when it comes to the applicability of these models in the Greek paradigm. It is a necessary prerequisite that clinical and theoretical knowledge of services that care for populations with a high prevalence of BPD is updated, and the current review makes a contribution in this direction.

Adolescent aggression has received a wide and longtime attention in scientific research, because of the extent of the phenomenon in this age group and of the negative consequences it inflicts on affected adolescents, and their human environments. The aim of this cross-sectional study was to determine the proportion (of high levels) of aggressive behaviors (physical, verbal, and direct aggression, anger, and hostility) in an urban sample of adolescent students, as well as to investigate associations between the occurrence of these behaviors, and adolescents' characteristics and mental health problems. The sample consisted of 2050 students attending the second grade of 49 random selected High Schools and Senior High Schools of the Regional Unit of the Central Sector of Attica and Piraeus. The Buss- Perry Aggression Questionnaire was administered to measure participants' aggression behaviors, while the Strength and Difficulties Questionnaire was also used to estimate their mental health and behavioral difficulties. Information about adolescents' individual, family, and school characteristics, was also collected. Results of the statistical analysis showed that the occurrence rates of high levels of participants' aggressive behaviors ranged between 2.2 (for total aggression) and 10.5% (for anger). Among individual characteristics, gender (with boys predominating in physical and direct aggression and girls in anger), (older) age, and sports activity (to direct aggression) were related to participants' aggressive behaviors. On the other hand, non-intact family structure and household insecurity food intake were positive correlated with specific aggressive behaviors, while pocket money allowance was positive associated with all of them. Concerning participants' mental health and behavioral issues, conduct problems and hyperactivity/ inattention were positive correlated with all investigated aggressive behaviors. In conclusion, the vast majority of the Central Sector of Attica and Piraeus adolescents did not seem to show high levels of aggressive behaviors (except anger). Nevertheless, considering this study outcomes (such as the "aggressive" burden of older adolescents, the role of family structure and pocket money allowance, as well as the co-occurrence with mental and behavioral problems), further longitudinal study is required to better understand the mechanisms that facilitate adolescent aggression.

Humans, as social beings, rely on interaction in order to survive and "flourish". By nature, they are "weak" and when in solitary, their freedom is jeopardized. Connecting with others, intimacy, physical contact, and the sense of belonging are core needs, and once recognized as such, they ultimately serve one's freedom. In this context, social interaction serves as a fundamental factor for survival. The creation of bonds improves one's position in the evolutionary process, and paves the way towards the ultimate "goal" of existence. The COVID-19 pandemic and the measures to control its spread have disrupted every aspect of human activity. Social, academic, cultural, business, and economic activities have been drastically modified.1 The conscious experience of the threat of life has been a ubiquitous "dramatic reminder of human vulnerability". The environment became unintelligible, death was "present" at all times. People tried to find a new meaning of life and discover a new sense of self-worth. The triggered vulnerability, the isolation from friends and relatives that to date validated one's self-esteem, the unprecedented obstacles with respect to career goals, and unexpected job losses affected the global view of things.1 The restrictive measures and the resulting urgent vaccination created "dystopian" conditions, under which deriving pleasure became a luxury. Scientific data have shown that social distancing has led to high levels of psychological distress. Primary research conducted during the social restrictions as well as subsequent meta-analytical studies have revealed increased irritability, emotional instability, and ultimately an increase in emotional and anxiety disorders' prevalence.2 Undoubtedly, mental and sexual health share a strong and bidirectional relationship.3 International health organizations emphasize the positive impact of a healthy sexual life on psychological well-being. Sexual well-being can serve - along with other factors - as a protective measure against the development of psychopathology, while stable sexual activity acts as a safeguard for well-being in general. The negative relationship between psychological symptoms and sexual gratification has been repeatedly documented by research, highlighting the impact of anxiety on sexual desire, arousal, and overall satisfaction with sexual life.4 Given this relationship and the increased emotional vulnerability during the pandemic, one might wonder how this reciprocal path has been affected. Physical intimacy, one of the basic expressions of the connection between partners, could not remain unaffected. During the first year of the pandemic and the restrictive measures, it became difficult for partners to meet. Due to the measures and discouragement of gatherings, a strong fear of infection gradually developed and avoidance behaviors emerged. In some countries, there were recommendations for physical-sexual interactions' limitation, and use of masks in intimate situa

Attention deficit hyperactivity disorder (ADHD) is one of the most commonly occurring developmental disorders of childhood, which can often be present after adulthood. The main symptoms of ADHD are distraction, impulsiveness, and hyperactivity, which are common in childhood, and for this reason, the diagnosis is usually delayed. At the same time, in several cases, the problems caused by ADHD (such as behavioral and social adjustment problems and problems in school performance) are considered as results of other co-existing situations (such as family problems, environmental change, and developmental pathologies). For this reason, ADHD often remains undiagnosed or misdiagnosed and even when it is accurately diagnosed, a comprehensive model of a combination of therapeutic approaches that are required to treat it, is not always applied. Today, there are a plethora of tests used to assess specific deficits presented by both children and adolescents with ADHD. The purpose of this literature review was to present tools and tests used in the evaluation of children and adolescents with ADHD. Search was performed on PubMed until February 20, 2021, without time limit for the publication of scientific papers. Studies were excluded if they were not published in English language, were conducted on animals and were case studies, editorials, and letters to the editor. Of the scientific papers retrieved, 15 were included in the systematic review. Some of the specialized tests used in the evaluation of children and adolescents with ADHD are the Children's Color Trails Test (CCTT), the Test of Variables of Attention (TOVA), the Continuous Performance Test (CPT), the Conner's' Parent Rating Scale (CPRS), the Child Behavior Checklist (CBCL), the Visual and Auditory Continuous Performance Testing (IVA-CPT), the Visual Analog Scale (VAS), the 30-item Semi-Structured Interview with Parents (CAPA- RAD), the Controlled Oral Word Association Test (COWAT), the Conners' Teacher Rating Scale (CTRS). In conclusion, there are a number of evaluation tools that can be used to evaluate specific deficits presented by children and adolescents with ADHD, as well as to evaluate the course of treatment, but also to distinguish children and adolescents with ADHD from those with other types of cognitive and learning disorders.

One of the issues that have risen the past few decades due to excessive use of technological advances is internet gaming disorder (IGD). Past research has concluded that there is a negative association between IGD and exercise as well as a positive association between IGD and attention deficit hyperactivity disorder (ADHD). However, the existing studies on these subjects are scarce. Furthermore, researchers have showcased that symptoms of depression, anxiety and stress are positively associated with IGD and ADHD but negatively associated with exercise. Consequently, maybe these symptoms mediate the relationships between IGD, exercise and ADHD. The purpose of the present study is to investigate the relationship between IGD and exercise as well as between IGD and ADHD. A correlational study was conducted on 515 adults through Google forms. The Internet Gaming Disorder Scale-Short-Form was used to detect IGD symptoms, the Leisure-Time Exercise Questionnaire was utilized so as to evaluate participants' leisure - time exercise habits, and the Barkley Adult ADHD Rating Scale was used to assess ADHD symptoms. Furthermore, the Depression, Anxiety and Stress Scale-21 was utilized to evaluate symptoms of depression, anxiety, and stress. It was found that there is a negative correlation between IGD symptoms and leisure time exercise as well as a positive correlation between IGD symptoms and ADHD symptoms. Moreover, when taking all the variables that were examined into consideration, it was indicated that inattention symptoms and impulsivity symptoms were significantly associated with IGD symptoms whereas symptoms of depression were partially and significantly mediating the association between IGD symptoms and Attention deficit as well as the association between IGD symptoms and Impulsivity. The findings of the current study suggest that people who deal with IGD symptoms tend to exercise less on their free time. Additionally, people with more IGD symptoms display not only more ADHD symptoms, symptoms of inattention and impulsivity specifically, but also more symptoms of depression. Therefore, clinicians should evaluate the possible coexistence of such symptoms when treating people with IGD, in order to prevent as well as treat more efficiently IGD and its consequences.