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Results of esketamine administration in a Greek population; A case series. 在希腊人群中使用埃斯卡他敏的结果;病例系列。
Q3 Medicine Pub Date : 2024-10-08 Epub Date: 2024-05-29 DOI: 10.22365/jpsych.2024.006
Petros Fotiadis, Eleni Tsalkitzi, Dimos Dimellis, Konstantinos Rantis, Athanasios Tsimpiris, Georgios Pagkalos

Esketamine is a non-selective, competitive antagonist of the N-methyl-D-aspartate (NMDA) receptor in the brain. Through NMDA receptor antagonism, esketamine causes a transient increase in glutamate release, leading to increases in neurotrophic signaling and restoration of synaptic function in brain regions involved in mood regulation and emotional behavior. Several randomized clinical trials have shown its effectiveness in reducing the symptoms of depression in some people, despite its short-term side effects that include mainly disorientation, dizziness, nausea, and increased blood pressure. In 2019, the United States Food and Drug Administration (FDA) as well as the European Medicines Agency approved the use of esketamine nasal spray in combination with an oral antidepressant for treatment-resistant depression in adults. Our study aimed to evaluate the effectiveness of this new therapeutic proposal in a case series of five Greek patients with treatment- resistant depression. Intranasal esketamine was administered under medical supervision in combination with an oral antidepressant. Depressive symptoms were evaluated at three time points (baseline, end of treatment, and one-year post-treatment) using the Montgomery-Åsberg Depression Rating Scale (MADRS), the Patient Health Questionnaire (PHQ-9), the CGI Clinical Global Impression Scale, and the Perceived Deficits Questionnaire for Depression (PDQ-D). Possible side effects were assessed using the Richmond Suppression Agitation Scale (RASS), the Sheehan Disability Scale (SDS), the CADSS Disruptive States Scale, and a predefined list of adverse events (AEs) and serious adverse events (SAEs). Patients followed an individualized treatment plan for seven to twelve months depending on the achievement of an adequate response. Statistical analysis of the results revealed a significant improvement (p<0.05) on all scales used. All participants maintained their level of improvement at follow-up after twelve months. Adverse effects were found to be mild and tolerable. It is worth noting that significant side effects were reported only by the two patients with comorbid personality disorder. The results, despite limited to a small sample, indicate the positive effect of esketamine on the stable reduction of depressive symptoms among patients with resistant depression, even after the completion of treatment.

艾司卡明是大脑中N-甲基-D-天冬氨酸(NMDA)受体的一种非选择性、竞争性拮抗剂。通过NMDA受体拮抗作用,艾司卡胺能使谷氨酸释放短暂增加,从而增加神经营养信号传导,恢复大脑中涉及情绪调节和情感行为的区域的突触功能。几项随机临床试验表明,尽管它的短期副作用主要包括迷失方向、头晕、恶心和血压升高,但仍能有效减轻一些人的抑郁症状。2019年,美国食品和药物管理局(FDA)以及欧洲药品管理局批准将艾司氯胺酮鼻喷雾剂与口服抗抑郁药联合用于治疗成人耐药性抑郁症。我们的研究旨在评估这一新治疗方案在五名希腊耐药抑郁症患者中的疗效。在医生的指导下,患者在口服抗抑郁药的同时鼻内注射艾司氯胺酮。在三个时间点(基线、治疗结束和治疗后一年)使用蒙哥马利-阿斯伯格抑郁评定量表(MADRS)、患者健康问卷(PHQ-9)、CGI临床总体印象量表和抑郁知觉缺陷问卷(PDQ-D)对抑郁症状进行评估。使用里士满抑制躁动量表 (RASS)、希恩残疾量表 (SDS)、CADSS 破坏状态量表以及预定义的不良事件 (AE) 和严重不良事件 (SAE) 列表评估可能出现的副作用。患者按照个性化的治疗方案接受七到十二个月的治疗,具体取决于是否取得了充分的反应。统计分析结果显示,治疗效果显著改善(p
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引用次数: 0
Quality of life and psychopathology in different COVID-19 pandemic periods: A longitudinal study. 不同 COVID-19 大流行时期的生活质量和精神病理学:纵向研究。
Q3 Medicine Pub Date : 2024-10-08 Epub Date: 2024-05-29 DOI: 10.22365/jpsych.2024.010
Eugenia Triantafillou, Panagiotis Tsellos, Nikos Christodoulou, Chara Tzavara, George N Christodoulou

Τhe aim of this longitudinal study was to investigate the effect of the COVID-19 pandemic on the mental health and quality of life (QoL) of the general population in the region of Attica, Greece, during the third year of the pandemic (2022), and tο compare the findings with those of a survey conducted in the first year (2020). Our sample consisted of 130 participants and the study was conducted through phone interviews. The instruments used were: the World Health Organisation QoL instrument, the Depression-Anxiety-Stress Scale, the Body Vigilance Scale, the Dimensional Obsessive-Compulsive Scale, as well as socio-demographic data and questions on stressors related to COVID-19. The findings of the study were the following: (1) Regarding the comparison of the variables between the first and the third year of the pandemic in the total sample: a) In comparison to the first year, in the third year we observed a significant decrease in negative feelings caused by the pandemic; b) obsessive compulsive (OC) and hypochondriacal symptomatology were significantly reduced, and the fact that participants felt safe following vaccination had a statistically significant effect on this decrease; c) job insecurity was aggravated; d) QoL remained low and even deteriorated in the Environment domain; f) no changes were found in Depression-Stress. (2) Regarding participants who were contaminated, there was a significant increase in negative feelings during the third year of the pandemic. Moreover, QoL decreased in the Physical, Psychological health, Environment domains, as well as in OC symptomatology. (3) Depression-Stress, hypochondriacal symptomatology, and the case of contamination were the predominant factors negatively associated with the dependent variables of QoL. (4) Vaccination was found to contribute to high levels of the QoL Environment domain score. (5) Anxiety, hypochondriacal symptomatology, fear of contamination, and negative feelings seemed to predict OC symptomatology. (6) The most vulnerable groups, in terms of QoL and mental health, were men, older and lower-educated people. Overall, it was found that the negative psychosocial impact of the pandemic persisted, especially on people who had fallen ill during the third year of the pandemic. Therefore, targeted psychotherapeutic interventions should be implemented, especially for those who got infected.

这项纵向研究旨在调查 COVID-19 大流行在大流行的第三年(2022 年)对希腊阿提卡地区普通人群的心理健康和生活质量(QoL)的影响,并将调查结果与第一年(2020 年)的调查结果进行比较。我们的样本包括 130 名参与者,研究通过电话访谈进行。使用的工具包括:世界卫生组织 QoL 工具、抑郁-焦虑-压力量表、身体警觉量表、维度强迫量表、社会人口学数据以及与 COVID-19 相关的压力源问题。研究结果如下(1) 关于大流行第一年和第三年总样本变量的比较:a) 与第一年相比,在第三年我们观察到由大流行病引起的负面情绪显著减少;b) 强迫 症(OC)和疑病症状显著减少,接种疫苗后参与者感到安全这一事实对这一减少有显 著的统计学影响;c) 工作不安全感加剧;d) QoL 仍然很低,甚至在环境领域有所恶化;f) 抑郁-压力没有发 现变化。(2) 关于受污染的参与者,在大流行的第三年,负面情绪显著增加。此外,身体、心理健康和环境领域的 QoL 以及 OC 症状都有所下降。(3) 抑郁-压力、疑病症状和污染病例是与 QoL 因变量负相关的主要因素。(4) 接种疫苗导致 QoL 环境域得分较高。(5) 焦虑、疑病症状、对污染的恐惧和负面情绪似乎可预测 OC 症状。(6) 就 QoL 和心理健康而言,最脆弱的群体是男性、老年人和低学历者。总之,研究发现,大流行病对社会心理的负面影响持续存在,尤其是对在大流行病第三年患病的人。因此,应采取有针对性的心理治疗干预措施,特别是针对那些感染者。
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引用次数: 0
Prisoners' perceptions and satisfaction with telepsychiatry services in Greece. 希腊囚犯对远程精神病治疗服务的看法和满意度。
Q3 Medicine Pub Date : 2024-10-08 Epub Date: 2024-05-29 DOI: 10.22365/jpsych.2024.007
Evangelia Karachaliou, Phoebe Douzenis, Fotios Chatzinikolaou, Nikos Pantazis, Sophia Martinaki, Konstantinos Tasios, Athanasios Douzenis

Telepsychiatry is an effective tool to support and provide mental health services to prison inmates. In Greece, telepsychiatry was formally applied in two correctional facilities in 2018. The objective of this study was to compare inmates' perceptions and satisfaction with telepsychiatry versus face-to-face consultation. The sample consisted of 100 male inmates with a multicultural background and prior experience with both methods of services provision. The data were obtained through a Demographic Data Questionnaire, a Participant Satisfaction Questionnaire to assess satisfaction with face-to-face psychiatric services, and another Participant Satisfaction Questionnaire to assess satisfaction with telepsychiatric services. The results have shown a higher level of satisfaction with telepsychiatry compared to face-to-face care. Statistically significant improvements (all p-values <0.001) were noted in: waiting times, support for relapse prevention, follow up, quality of mental health care, quality of care in the management of psychiatric problems and related medication, behaviour of psychiatrists, duration of the assessment, sense of comfort, and confidentiality. Telepsychiatry has proved to be an acceptable way of approaching and supporting inmates in Greece, with most of the participants expressing high acceptance, satisfaction, and preference rates. Implications for additional research and further development of telepsychiatry are discussed.

远程精神病学是支持和为监狱囚犯提供心理健康服务的有效工具。在希腊,远程精神病学于2018年正式应用于两所惩教机构。本研究旨在比较囚犯对远程精神病学与面对面咨询的看法和满意度。样本由 100 名具有多元文化背景的男性囚犯组成,他们之前都曾使用过这两种服务方式。数据通过人口数据调查表、评估面对面精神科服务满意度的参与者满意度调查表以及评估远程精神科服务满意度的另一份参与者满意度调查表获得。结果显示,与面对面治疗相比,远程精神病治疗的满意度更高。在统计上有明显改善(所有 p 值为
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引用次数: 0
Effects of antipsychotic medications in glucose and lipid metabolism at the fasted state in drug-naïve first episode patients with psychosis after six months and three years of treatment. 抗精神病药物在治疗 6 个月和 3 年后对初次服药的精神病患者空腹状态下葡萄糖和脂质代谢的影响。
Q3 Medicine Pub Date : 2024-10-08 Epub Date: 2024-05-29 DOI: 10.22365/jpsych.2024.008
Petros Petrikis, Stelios Tigas, Alexandros T Tzallas, Georgios Ntritsos, Chrissa Sioka, Georgios Georgiou, Andreas Karampas, Petros Skapinakis, Christos Mantas, Thomas Hyphantis

Diabetes and dyslipidemia are common in patients with psychosis and may be related to adverse effects of antipsychotic medications. Metabolic disturbances in first-episode patients with psychosis are common, even prior to any antipsychotic treatment, and antipsychotic medications are implicated in the development of metabolic syndrome, at least in the long run. We therefore aimed to follow a group of drug-naïve, first-episode patients with psychosis at different time points (baseline, six months, and 36 months after the initiation of antipsychotic treatment) in order to evaluate the progression of metabolic abnormalities after antipsychotic therapy and the time-course of their onset. We assessed glucose and lipid metabolism during the fasted state in 54 drug-naïve patients with first-episode psychosis (FEP) before the initiation of any antipsychotic treatment and compared them with matched controls. The same parameters were assessed in the patient group (n=54) after six months of antipsychotic treatment and in a subgroup of patients (n=39) after three years of continuous and stable treatment in comparison to baseline. Measurements were obtained for fasting serum concentrations of total cholesterol, triglycerides, high density lipoprotein (HDL), glucose, insulin, connecting peptide (C-peptide), homeostatic model assessment index (HOMA-IR), glycated hemoglobin (HbA1c) and body mass index (BMI). Insulin, C-peptide, triglyceride levels, and HOMA-IR index were significantly higher compared to controls. Total cholesterol, triglyceride levels and BMI, increased significantly in the patient group after six months of antipsychotic treatment. After three years of continuous antipsychotic treatment, we found statistically significant increases in fasting glucose, insulin, total cholesterol, triglyceride levels, HbA1c, HOMA-IR index, and BMI compared to baseline. In conclusion, FEP patients developed significant increases in BMI and serum lipid levels as soon as six months after antipsychotic treatment. These metabolic abnormalities persisted following 36 months of treatment and in addition, increases in fasting glucose, insulin, HbA1c and HOMA-IR were observed compared to baseline.

糖尿病和血脂异常在精神病患者中很常见,可能与抗精神病药物的不良反应有关。即使在接受任何抗精神病药物治疗之前,精神病初发患者的代谢紊乱也很常见,而抗精神病药物与代谢综合征的发展有关,至少从长远来看是如此。因此,我们在不同的时间点(基线、6 个月和开始抗精神病药物治疗后 36 个月)对一组未接受过药物治疗的首发精神病患者进行随访,以评估抗精神病药物治疗后代谢异常的进展情况及其发病的时间过程。我们评估了 54 名未服药的首发精神病(FEP)患者在开始接受任何抗精神病药物治疗前的空腹状态下的葡萄糖和脂质代谢情况,并与匹配的对照组进行了比较。患者组(54 人)在接受抗精神病药物治疗 6 个月后,以及亚组患者(39 人)在接受持续稳定的治疗 3 年后,与基线进行比较,评估了相同的参数。对空腹血清总胆固醇、甘油三酯、高密度脂蛋白、葡萄糖、胰岛素、连接肽(C肽)、稳态模型评估指数(HOMA-IR)、糖化血红蛋白(HbA1c)和体重指数(BMI)的浓度进行了测量。与对照组相比,胰岛素、C 肽、甘油三酯水平和 HOMA-IR 指数均显著升高。抗精神病药物治疗六个月后,患者组的总胆固醇、甘油三酯水平和体重指数明显增加。经过三年的持续抗精神病治疗后,我们发现与基线相比,患者的空腹血糖、胰岛素、总胆固醇、甘油三酯水平、HbA1c、HOMA-IR 指数和 BMI 均有统计学意义上的显著增加。总之,FEP 患者在接受抗精神病药物治疗 6 个月后,体重指数和血清脂质水平就会显著升高。这些代谢异常在治疗 36 个月后仍持续存在,此外,与基线相比,还观察到空腹血糖、胰岛素、HbA1c 和 HOMA-IR 的增加。
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引用次数: 0
Being a medical trainee in Greece: Aims and key aspects of the Greek Survey of Medical Work and Education. 在希腊接受医学培训:希腊医学工作和教育调查的目标和主要方面。
Q3 Medicine Pub Date : 2024-10-08 Epub Date: 2024-09-25 DOI: 10.22365/jpsych.2024.016
Argyris Stringaris, Paraskeui Peiou, Ioannis Marios Rokas, Nikolaos Saridis, Lampros Orion Asimakopoulos
<p><p>Anyone reading this text has probably been a medical trainee once. What was your training like? More importantly, did anyone during your training ask you what your training was like? For example, did anyone ask you if you were satisfied with your training or if you worked a little or a lot? Probably not. The origin of medical specialty training is that of informal apprenticeship. The apprentice was grateful to the master for accepting him; there was no room for questions or disagreements. If you haven't read Somerset. Maugham's "Human Bondage" (he was medically trained himself), it is worth reading as a fascinating testimony to the education of our not so distant professional ancestors.1 The creation of medical specialisation training programs (starting in Paris with the US and UK following) did not change this situation much. Medical schools were slowly filled with the brightest minds of each country because of entrance examination and the prestige of the profession. From the evidence we have, medical students are often conscientious (in the sense of a personality trait) and hard working.2 Many believe that they perform more than just a profession and therefore do not see themselves as common workers who will demand changes in the way they work or challenge their employer or trainer. Additionally, asking for changes may also be perceived as a sign of weakness, which does not fit with the image of the doctor in society, which is that of the fallible and self-sacrificing hero. In other words, both social circumstances and identity issues have stood in the way of certain actions to be taken, i.e., asking, among other things, what specialty training is like for trainee doctors. A point of inflection was the processes leading up to the 2003 Working Time Directive in the European Union - the result of two famous court decisions, one in Spain and one in Germany, that had an impact on case law.3-5 It is worth noting that until then many of us were on call for 72 hours (Friday - Saturday - Sunday) and on Monday it was taken for granted that we would continue examining patients and doing other clinical work. Around the same time, in America, the well-known "duty hour limits" were proposed, setting, among other things, a maximum of 80 hours of work per week for medical residents. Until then, some trainee doctors were seen as residing within the hospital, offering on-call services in exchange for the training they received. Hence the term resident doctors.6 These changes in labour law have also triggered change in other areas. Gradually, trainees' views were taken into account even in the evaluation of the "authority", i.e., the supervisor (see British 360 evaluation including trainee feedback). The British regulatory agency of medical professions, the General Medical Council (GMC), conducts an annual evaluation of the quality and acceptability of training among residents and their trainers in the form of questionnaires.7 In Greece, and in other Europ
读过这篇文章的人都可能曾经是一名医学实习生。你的培训是什么样的?更重要的是,在你受训期间,有没有人问过你受训的感受?例如,有没有人问过你对自己的培训是否满意,有没有人问过你工作少还是工作多?可能没有。医学专业培训的起源是非正式学徒制。学徒对师傅的收留心存感激,没有质疑和异议的余地。如果您没有读过萨默塞特。毛姆的《人类的束缚》(他本人也接受过医学培训),这本书值得一读,因为它是我们并不遥远的职业先辈们接受教育的精彩见证1。1 医学专业培训计划的设立(从巴黎开始,美国和英国紧随其后)并没有改变这种状况。由于入学考试和医学专业的声望,各国医学院慢慢招满了最聪明的学生。从我们掌握的证据来看,医科学生通常都很认真(从人格特质的意义上说)和勤奋。2 许多人认为,他们从事的不仅仅是一种职业,因此不认为自己是会要求改变工作方式或挑战雇主或培训师的普通工人。此外,要求改变也可能被视为软弱的表现,这与医生在社会中的形象不符,即容易犯错和自我牺牲的英雄形象。换句话说,社会环境和身份问题阻碍了某些行动的开展,例如,除其他事项外,询问实习医生的专业培训是什么样的。3-5 值得注意的是,在此之前,我们中的许多人都是 72 小时(周五-周六-周日)随叫随到,而在周一,我们会理所当然地继续检查病人和从事其他临床工作。大约在同一时间,美国提出了著名的 "值班时间限制",规定住院医生每周最多工作 80 小时。在此之前,一些见习医生被视为居住在医院内,提供随叫随到的服务,以换取所接受的培训。6 劳动法的这些变化也引发了其他领域的变革。逐渐地,甚至在对 "权威"(即主管)进行评估时,也会考虑受训者的意见(见英国 360 度评估,包括受训者反馈)。英国医学专业管理机构--医学总理事会(GMC)每年都会以调查问卷的形式对住院医师及 其培训师的培训质量和可接受性进行评估。希腊的医学专业监管机构--卫生部和医学协会都没有进行类似的调查。以往有关希腊专科受训人员的研究要么是几年前进行的,要么因样本量小或研究的专科范围狭窄而受到限制。.8-11 为了填补这一文献空白,我们小组决定通过调查进行自己的评估。我们将其命名为 "希腊医疗工作与教育调查"(希腊语缩写为 EIPEs)。促使我们做出这一决定的原因是,希腊卫生部突然决定在专科培训中引入入学考试,而我们小组内部对这一决定的利弊也存在分歧。在希腊开展这项研究有许多重要原因。国家卫生系统 ESY(所有同事都在这里接受培训)的情况相当糟糕,长期供不应求,等待名单很长,许多医生都去了私营部门。由于我国在医疗专家购买力方面处于较低水平,因此医生的工资远低于其他欧洲国家的同行(图 1)。这一事实,再加上医疗机构的基础设施建设和人员配备不尽人意,加剧了年轻受训人员和医学专家向国外(主要是塞浦路斯、德国和英国)的外流,从而进一步恶化了希腊国家医疗服务体系的可持续性(图 2)。我们的研究不同于以往的研究,因为它在很大程度上是由对上述情况有切身体会的受训人员设计的。它涉及的问题多种多样,包括值班时间、休息时间、对工作时间是否符合欧洲立法的看法,甚至是对卫生部管理的信任度。EIPEs 是一项全国范围的横断面研究,针对所有医学专业的受训人员。
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引用次数: 0
Impact of COVID-19 outbreak on subjective sleep during lockdown: relation with resilience characteristics. COVID-19 疫情对封锁期间主观睡眠的影响:与复原力特征的关系。
Q3 Medicine Pub Date : 2024-10-08 Epub Date: 2024-02-27 DOI: 10.22365/jpsych.2024.004
Maria Ntafouli, Rigas Soldatos, Dimitris Dikeos

The SARS-CoV-2 pandemic had a considerable impact on both the physical and mental health of people. Resilience is a psychological characteristic reflecting the ability to overcome or adapt to difficulties such as adversity, trauma, or extremely stressful situations. People with high resilience have been shown to exhibit lower levels of anxiety, stress and depression when faced with a stressful event. Sleep is particularly sensitive to anxiety and stress. The aim of this study was to investigate the impact of COVID-19 pandemic on sleep quantity, quality, and habits, while considering resilience as a factor. A total of 1260 individuals were recruited through an online survey. The variables that were assessed were socio-demographic, sleep habits and sleep disorders history, the Athens Insomnia Scale (AIS), the 25-item version of the Connor-Davidson Resilience Scale (CD-RISC), and any work/financial consequences during the first COVID-19 lockdown. The results showed that sleep habits during the lockdown changed for many of the participants. Their sleep schedule moving towards earlier or later for 9% and 67% of them, respectively; 38% of the participants were found to suffer from insomnia, based on the AIS score. A higher score on the CD-RISC was associated with better sleep. In conclusion, our study confirmed previous studies identifying quantitative and qualitative changes in sleep during the COVID-19 lockdown. It also expanded on the previous findings by identifying the correlation between sleep and resilience during the stressful period of the COVID-19 lockdown.

SARS-CoV-2 大流行对人们的身心健康造成了相当大的影响。复原力是一种心理特征,反映了克服或适应逆境、创伤或极度紧张等困难的能力。事实证明,抗压能力强的人在面对压力事件时,焦虑、压力和抑郁的程度较低。睡眠对焦虑和压力尤为敏感。本研究旨在调查 COVID-19 大流行病对睡眠数量、质量和习惯的影响,同时考虑抗压能力这一因素。通过在线调查共招募了 1260 人。评估的变量包括社会人口学、睡眠习惯和睡眠障碍史、雅典失眠量表(AIS)、25 项康纳-戴维森复原力量表(CD-RISC),以及在第一次 COVID-19 封锁期间的任何工作/财务后果。结果显示,许多参与者在封锁期间的睡眠习惯发生了变化。分别有 9% 和 67% 的参与者的睡眠时间提前或推迟;根据 AIS 评分,38% 的参与者患有失眠症。CD-RISC 得分越高,睡眠质量越好。总之,我们的研究证实了之前的研究发现的 COVID-19 封锁期间睡眠的定量和定性变化。此外,我们还通过确定 COVID-19 封锁期间睡眠与抗压能力之间的相关性,对之前的研究结果进行了扩展。
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引用次数: 0
Dimensionality and psychometric properties of the Parent Diabetes Distress Scale-Greek (PDDS-Gr). 父母糖尿病困扰量表的维度和心理测量特性-希腊语(PDDS-Gr)。
Q3 Medicine Pub Date : 2024-10-08 Epub Date: 2023-09-29 DOI: 10.22365/jpsych.2023.020
Emmanouil S Benioudakis, Argyroula Kalaitzaki, Eleni Karlafti, Maria A Makri, Theodosia Arvanitaki, Maria-Alexandra Kalpou, Christos Savopoulos, Triantafyllos Didangelos

Type 1 diabetes (T1D) is a chronic disease characterised by insulin deficiency due to autoimmune destruction of beta-pancreatic cells. T1D, formerly known as juvenile diabetes, is the most common form of diabetes in children and adolescents. On diagnosis, parents of children with TID experience considerable stress, because they need to care for a child in a challenging and life-threatening situation that requires adherence to an intensive medical regimen, constant monitoring of, and coping with their child's condition. T1D is a complex condition that affects both children and their parents in many aspects of their daily lives. This study presents the psychometric properties of the Greek translation of the Parent Diabetes Distress Scale (PDDS), which assesses diabetes distress in parents of children with T1D. A sample of 95 parents, mainly mothers (88.4%), with a mean age of their children 12.2 years (± 3.6) and a diabetes duration of 4.7 years (± 3.4), completed the Greek translation of the PDDS. Exploratory factor analysis (EFA) revealed a five-factor model: 'Parent/child relationship distress', 'Personal distress', 'Child diabetes management distress', 'Future distress', and 'Healthcare team distress'. Confirmation Factor Analysis (CFA) confirmed the construct validity of the scale. The internal consistency indices (Cronbach alpha) for the subscales ranged from 0.69 to 0.89, while the unidimensional structure had an alpha of 0.90. Furthermore, convergent validity was shown with moderate positive correlations between the PDDS-Gr and the subscales of the DASS-21 (depression, anxiety, and stress), the child's age (in years), and the HbA1c value. Finally, parents of children with inadequate glycemic control (HbA1c ≥ 7%) presented higher scores on both the unidimensional structure and the subscales 'Parent/child relationship distress' and 'Healthcare team distress' of the PDDS-Gr. The PDDS-Gr is a valid and reliable tool for assessing diabetes distress in parents of children with T1D and can be used in both clinical and research settings.

1型糖尿病(T1D)是一种慢性疾病,其特征是由于自身免疫性破坏β-胰腺细胞而导致胰岛素缺乏。T1D,以前被称为青少年糖尿病,是儿童和青少年最常见的糖尿病形式。在诊断时,患有TID的儿童的父母会经历相当大的压力,因为他们需要照顾处于具有挑战性和危及生命的情况下的儿童,这需要坚持强化医疗方案,不断监测和应对孩子的病情。T1D是一种复杂的疾病,影响儿童及其父母日常生活的许多方面。本研究介绍了父母糖尿病困扰量表(PDDS)的希腊语翻译的心理测量特性,该量表评估了T1D儿童父母的糖尿病困扰。以95名父母为样本,主要是母亲(88.4%),他们的孩子平均年龄为12.2岁(±3.6),糖尿病持续时间为4.7年(±3.4),完成了PDDS的希腊语翻译。探索性因素分析(EFA)揭示了一个五因素模型:“父母/孩子关系困扰”、“个人困扰”、儿童糖尿病管理困扰、“未来困扰”和“医疗团队困扰”。确认因子分析证实了量表的结构有效性。分量表的内部一致性指数(Cronbachα)在0.69至0.89之间,而一维结构的α为0.90。此外,PDDS-Gr与DAS-21分量表(抑郁、焦虑和压力)、儿童年龄(以年为单位)和HbA1c值之间存在中度正相关,显示出收敛有效性。最后,血糖控制不足(HbA1c≥7%)儿童的父母在PDDS-Gr的一维结构和分量表“父母/儿童关系困扰”和“医疗团队困扰”上都表现出更高的分数。PDDS-Gr是评估T1D儿童父母糖尿病困扰的有效可靠工具,可用于临床和研究环境。
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引用次数: 0
Dimensionality and psychometric properties of the Greek version of the Diabetes Impact and Device Satisfaction (DIDS) scale. 希腊语版糖尿病影响和设备满意度量表(DIDS)的维度和心理测量特性。
Q3 Medicine Pub Date : 2024-09-24 DOI: 10.22365/jpsych.2024.017
Emmanouil S Benioudakis, Argyroula Kalaitzaki, Eleni Karlafti, Oxana Ahanov, Elisavet Kapageridou, Christos Savopoulos, Triantafyllos Didangelos

Type 1 diabetes mellitus (T1D) is a chronic condition with rising prevalence. The only treatment for individuals with T1D to prevent diabetes-related complications is exogenous insulin administration. Diabetes-related technology has significantly contributed to the management of T1D by reducing the burden of living with diabetes and providing greater flexibility in insulin management during daily activities. This study presents the psychometric properties of the Greek translation of the Diabetes Impact and Device Satisfaction (DIDS) Scale, which assesses satisfaction with the use of an insulin delivery device and the impact of diabetes management on individuals with T1D. A sample of 101 adults with T1D, mostly females (71.3%), with a mean age of 38.4 years (± 11.7), completed the translated Greek version of DIDS (DIDS-Gr). Exploratory factor analysis revealed three factors: 'Device Satisfaction', 'Diabetes Management Impact', and (new factor) 'Device Usability'. The internal consistency indices (Cronbach's alpha) for the subscales were 0.86, 0.71, and 0.60, respectively. Furthermore, convergent validity was demonstrated with moderate to high positive correlations between the DIDS-Grand the Diabetes Quality of Life Brief Clinical Inventory (DQoL-BCI) and its subscales, while divergent validity was also confirmed with weaker correlations with the depression subscale of the Hospital Anxiety and Depression Scale (HADS). Additionally, test-retest reliability and differential validity were present in our study. Therefore, DIDS-Gr is a valid and reliable measure for assessing the impact of diabetes on individuals with T1D and the satisfaction with the use of an insulin delivery device in Greece.

1 型糖尿病(T1D)是一种慢性疾病,发病率不断上升。T1D 患者预防糖尿病相关并发症的唯一治疗方法是注射外源性胰岛素。与糖尿病相关的技术大大促进了 T1D 的管理,减轻了糖尿病患者的生活负担,并在日常活动中提供了更大的胰岛素管理灵活性。本研究介绍了糖尿病影响和设备满意度(DIDS)量表希腊语译文的心理测量特性,该量表用于评估胰岛素给药设备使用的满意度以及糖尿病管理对 T1D 患者的影响。101名患有T1D的成人完成了希腊语翻译版的DIDS(DIDS-Gr),其中大部分为女性(71.3%),平均年龄为38.4岁(± 11.7)岁。探索性因子分析显示了三个因子:设备满意度"、"糖尿病管理影响 "和(新因素)"设备可用性"。子量表的内部一致性指数(Cronbach's alpha)分别为 0.86、0.71 和 0.60。此外,DIDS-Grand 与糖尿病生活质量简明临床量表(DQoL-BCI)及其各分量表之间的中度至高度正相关性证明了其收敛效度,而与医院焦虑抑郁量表(HADS)抑郁分量表之间较弱的相关性也证实了其发散效度。此外,我们的研究还发现了测试重复信度和差异效度。因此,DIDS-Gr 是一种有效、可靠的测量方法,可用于评估糖尿病对希腊 T1D 患者的影响以及对胰岛素给药装置使用的满意度。
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引用次数: 0
COVID-19 Fear and Coping Strategies during the Pandemic: Insights from Greek health services units. COVID-19 大流行期间的恐惧和应对策略:来自希腊医疗服务单位的启示。
Q3 Medicine Pub Date : 2024-09-18 DOI: 10.22365/jpsych.2024.013
Elpida Stratou, Aikaterini Toska, Aikaterini Gamvroula, Stavros Antonopoulos, Athanasios Moulopoulos, Theodora Rigopoulou, Kyriakos Souliotis, Maria Saridi

The aim of this study was to assess the fear caused by the COVID-19 pandemic among health services users in Greece. The study involved 1260 participants from three health services units in the prefecture of Corinthia. The COVID-19 Fear Scale (FCV-19S) and the Coping Orientation to Problems Experienced Inventory (Brief-COPE) were used to assess fear levels. Results showed that females experienced a significantly higher fear of COVID-19 (15.9 compared to 15.4), while the age group of>60 years had the highest mean score (16.6). Individuals in retirement showed a greater fear of COVID-19 (16.8), while health sector employees had lower fear scores (15.1). Chronically ill patients had a higher fear of COVID-19 (16.5 as opposed to 15.5 of healthy persons), while people considering that the COVID-19 pandemic will be dealt with soon presented lower levels of fear compared to those not considering it or being uncertain. According to the Brief-COPE questionnaire, fear of COVID-19 total scores was positively correlated with two of the coping subscales; the emotion-focused and the avoidant-coping. The study's findings can contribute to the identification of fear and coping strategies for the development of targeted interventions and mental health support programs during this global crisis.

本研究旨在评估 COVID-19 大流行在希腊医疗服务使用者中造成的恐慌。来自科林斯省三个医疗服务单位的 1260 名参与者参与了这项研究。研究采用了 COVID-19 恐惧量表(FCV-19S)和问题应对取向量表(Brief-COPE)来评估恐惧程度。结果显示,女性对 COVID-19 的恐惧程度明显更高(15.9 分,男性为 15.4 分),而年龄大于 60 岁的人群平均得分最高(16.6 分)。退休人员对 COVID-19 的恐惧感更高(16.8),而卫生部门的员工对 COVID-19 的恐惧感较低(15.1)。慢性病患者对 COVID-19 的恐惧程度较高(16.5 分,而健康人为 15.5 分),而认为 COVID-19 大流行将很快得到应对的人的恐惧程度低于不认为或不确定的人。根据 Brief-COPE 问卷,对 COVID-19 的恐惧总分与两个应对分量表(情绪专注型和回避型应对)呈正相关。这项研究的结果有助于确定恐惧和应对策略,以便在这场全球危机中制定有针对性的干预措施和心理健康支持计划。
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引用次数: 0
Validation of the Greek version of the Binge Eating Scale in a sample of binge eating disorder patients. 在暴饮暴食症患者样本中验证希腊版暴饮暴食量表。
Q3 Medicine Pub Date : 2024-09-18 DOI: 10.22365/jpsych.2024.014
Maria Karapatsia, Maria Evangelia Antoniadou, Chara Tzavara, Ioannis Michopoulos, Fragiskos Gonidakis

Binge eating disorder (BED), the most prevalent eating disorder, carries significant physical and psychological consequences. Therefore, there is a continuous need to assess binge eating symptomatology and evaluate the effectiveness of various therapeutic interventions. The Binge Eating Scale (BES), which is a self-administered questionnaire, is widely used to assess binge eating in obese people. It examines the person' s experience of binge eating and the emotional, cognitive, and behavioural symptoms associated with it. The purpose of the present study was to translate and adapt BES in Greek, as well as to assess the factorial structure of BES and evaluate its psychometric properties. A sample of 160 participants (90% females) with a mean age of 40.7 years (SD=11.5 years) and a mean body mass index (BMI) 37.5kg/m2 (SD=9.2kg/m2) completed the BES and the Eating Disorder Examination Questionnaire (EDE-Q). An exploratory factor analysis (EFA) was carried out to assess the construct validity of the BES in a sample of patients with BED according to DSM-5 who came for therapy at the Eating Disorders Unit at Eginition Hospital and the day center "Anasa". The two-factor structure fits the data best. Regarding internal consistency, the results were acceptable, with Cronbach' s alpha equal to 0.78. The BES has high significant correlations with the Eating Concern, Weight Concern, and Shape Concern subscales and the Global Score of EDE-Q, but not with the Restrain subscale. Also, BES has correlations with the specific EDE-Q questions about the frequency of objective and subjective binge eating episodes. A high correlation was obtained with the measure of ΒΜΙ too. The Greek version of BES is a valid and reliable scale to evaluate binge eating in a clinical population diagnosed with BED.

暴饮暴食症(BED)是最普遍的饮食失调症,会对身体和心理造成严重后果。因此,人们一直需要对暴食症状进行评估,并评价各种治疗干预措施的效果。暴食量表(BES)是一种自制问卷,被广泛用于评估肥胖者的暴食情况。它考察的是暴食者的暴食经历以及与之相关的情绪、认知和行为症状。本研究的目的是将 BES 翻译成希腊语并对其进行改编,同时评估 BES 的因子结构并评价其心理测量特性。160名平均年龄为40.7岁(SD=11.5岁)、平均体重指数(BMI)为37.5kg/m2(SD=9.2kg/m2)的参与者(90%为女性)完成了BES和进食障碍检查问卷(EDE-Q)。为了评估 BES 的结构效度,我们对来伊金特医院进食障碍科和 "Anasa "日间中心接受治疗的符合 DSM-5 标准的 BED 患者样本进行了探索性因子分析(EFA)。双因素结构最符合数据。关于内部一致性,结果是可以接受的,Cronbach's alpha 等于 0.78。BES 与 "进食关注"、"体重关注 "和 "体形关注 "分量表以及 EDE-Q 的总分具有高度显著的相关性,但与 "限制 "分量表没有相关性。此外,BES 与 EDE-Q 中有关客观和主观暴食发作频率的特定问题也有相关性。与ΒΜΙ的测量也有很高的相关性。希腊语版本的 BES 是一种有效且可靠的量表,可用于评估被诊断为暴食症的临床人群的暴食情况。
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引用次数: 0
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