Pub Date : 2022-08-01DOI: 10.32598/qums.16.5.377.1
R. Norouzi, Abolghasem Siadatpanah, Ruhollah Fateh, F. Sohrabi, Seyed Jafar Adnani Sadati
Background and Objectives: Cutaneous leishmaniasis is one of the most important health-threatening diseases in Iran and other countries. Glucantime is currently used to treat this disease, but due to its side effects and high resistance, alternative therapies such as the use of nanoparticles have been considered by researchers. This study aims to investigate the anti-leishmania activity of silver nanoparticles on Leishmania major in vitro. Methods: This is an experimental study on the anti-leishmania activities of silver nanoparticles at different concentrations of 0.75-0.96 µg/ml after 24, 48 and 72 hours of exposure to 106 live Leishmania major promastigotes. The numbers of live parasites were counted by Trypan Blue on a neobar slide using optical microscope (Hemocytometer method). Glucantime and distilled water were considered as positive and negative controls, respectively. The half-maximal inhibitory concentration (IC50) was calculated by SigmaPlot™ software, version 13. All reactions were done three times and their average was considered as final result. Results: All concentrations of silver nanoparticles had anti-leishmania activity, where the concentration of 96 µg/ml had the highest effect (100%) 72 hours after exposure. The IC50 was obtained 36.67, 27.2 and 21.08 µg/ml after 24, 48 and 72 hours of exposure, respectively. Conclusion: Silver nanoparticles have an inhibitory effect on the growth of Leishmania major in different concentrations. However, further in-vivo studies are needed to determine the effictivness of silver nanoparticles.
背景和目的:皮肤利什曼病是伊朗和其他国家最重要的健康威胁疾病之一。葡聚糖目前用于治疗这种疾病，但由于其副作用和高耐药性，研究人员已经考虑使用纳米颗粒等替代疗法。本研究旨在研究纳米银对利什曼原虫的体外抗利什曼原虫活性。方法:实验研究了不同浓度(0.75 ~ 0.96µg/ml)的银纳米颗粒对106只活的利什曼原虫(Leishmania major promastigotes)暴露24、48和72小时后的抗利什曼原虫活性。利用光学显微镜(血细胞计法)在新棒材载玻片上用台盼蓝法计数活虫数量。葡聚糖和蒸馏水分别作为阳性对照和阴性对照。半最大抑制浓度(IC50)由SigmaPlot™软件计算，版本13。所有反应均做三次，其平均值为最终结果。结果:所有浓度的纳米银均具有抗利什曼原虫活性，其中96 μ g/ml的浓度在暴露72小时后效果最高(100%)。暴露24、48和72 h后，IC50分别为36.67、27.2和21.08µg/ml。结论:不同浓度的纳米银对利什曼原虫的生长均有抑制作用。然而，需要进一步的体内研究来确定银纳米颗粒的有效性。
{"title":"In-vitro Study on the Anti-leishmania Effects of Silver Nanoparticles on Leishmanaia Major Promastigotes","authors":"R. Norouzi, Abolghasem Siadatpanah, Ruhollah Fateh, F. Sohrabi, Seyed Jafar Adnani Sadati","doi":"10.32598/qums.16.5.377.1","DOIUrl":"https://doi.org/10.32598/qums.16.5.377.1","url":null,"abstract":"Background and Objectives: Cutaneous leishmaniasis is one of the most important health-threatening diseases in Iran and other countries. Glucantime is currently used to treat this disease, but due to its side effects and high resistance, alternative therapies such as the use of nanoparticles have been considered by researchers. This study aims to investigate the anti-leishmania activity of silver nanoparticles on Leishmania major in vitro. Methods: This is an experimental study on the anti-leishmania activities of silver nanoparticles at different concentrations of 0.75-0.96 µg/ml after 24, 48 and 72 hours of exposure to 106 live Leishmania major promastigotes. The numbers of live parasites were counted by Trypan Blue on a neobar slide using optical microscope (Hemocytometer method). Glucantime and distilled water were considered as positive and negative controls, respectively. The half-maximal inhibitory concentration (IC50) was calculated by SigmaPlot™ software, version 13. All reactions were done three times and their average was considered as final result. Results: All concentrations of silver nanoparticles had anti-leishmania activity, where the concentration of 96 µg/ml had the highest effect (100%) 72 hours after exposure. The IC50 was obtained 36.67, 27.2 and 21.08 µg/ml after 24, 48 and 72 hours of exposure, respectively. Conclusion: Silver nanoparticles have an inhibitory effect on the growth of Leishmania major in different concentrations. However, further in-vivo studies are needed to determine the effictivness of silver nanoparticles.","PeriodicalId":20805,"journal":{"name":"Qom Univ Med Sci J","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86453412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-01DOI: 10.32598/qums.16.4.2566.1
Forooz Keshani, Z. Ghazavi, Marzie Sheikhrobati, Fatemeh Bahram Zadeh, N. Kargahi
Background and Objectives: In addition to diseases, patients with psychiatric disorders are at risk of oral and dental problems. The present study aims to investigate dental mouth and oral pathologic lesions in women with psychiatric disorders hospitalized in two hospitals in Isfahan, Iran. Methods: In this descriptive cross-sectional study, 43 women with psychiatric disorders hospitalized in Modarres and Khorshid hospitals in Isfahan, Iran in 2019 participated. Using a checklist, their demographic information including age, duration of hospitalization, type of disease, and educational level were recorded. Then, their oral cavity was examined in terms of dental health and pathological lesions. The data were analyzed in SPSS software, version 21 using Fishers’ exact test, Mann-Whitney U test, Kruskal-Wallis test, and logistic regression analysis. P<0.05 was statistically significant. Results: Of 43 women with a mean age of 36.7±13.8 years, 72% had oral lesions. The most common lesions were red-white lesions (23.1%). Moreover, 37.2% of women had dry mouth and 16.3% had self-inflicted oral injury. Dry mouth was significantly associated with the type of lesions and diseases. Self-inflicted oral injury was significantly associated with acute ulcers (P=0.001). Conclusion: Dry mouth and self-inflicted oral injury are high among hospitalized women with psychiatric disorders in Isfahan, Iran. Regular follow-up in psychiatric patients can reduce the incidence of oral lesions and dental caries, or help in their earlier diagnosis and better treatment.
{"title":"Dry Mouth and Oral Pathologic Lesions in Women With Psychiatric Disorders Hospitalized in Two Selected Hospitals in Isfahan, Iran","authors":"Forooz Keshani, Z. Ghazavi, Marzie Sheikhrobati, Fatemeh Bahram Zadeh, N. Kargahi","doi":"10.32598/qums.16.4.2566.1","DOIUrl":"https://doi.org/10.32598/qums.16.4.2566.1","url":null,"abstract":"Background and Objectives: In addition to diseases, patients with psychiatric disorders are at risk of oral and dental problems. The present study aims to investigate dental mouth and oral pathologic lesions in women with psychiatric disorders hospitalized in two hospitals in Isfahan, Iran. Methods: In this descriptive cross-sectional study, 43 women with psychiatric disorders hospitalized in Modarres and Khorshid hospitals in Isfahan, Iran in 2019 participated. Using a checklist, their demographic information including age, duration of hospitalization, type of disease, and educational level were recorded. Then, their oral cavity was examined in terms of dental health and pathological lesions. The data were analyzed in SPSS software, version 21 using Fishers’ exact test, Mann-Whitney U test, Kruskal-Wallis test, and logistic regression analysis. P<0.05 was statistically significant. Results: Of 43 women with a mean age of 36.7±13.8 years, 72% had oral lesions. The most common lesions were red-white lesions (23.1%). Moreover, 37.2% of women had dry mouth and 16.3% had self-inflicted oral injury. Dry mouth was significantly associated with the type of lesions and diseases. Self-inflicted oral injury was significantly associated with acute ulcers (P=0.001). Conclusion: Dry mouth and self-inflicted oral injury are high among hospitalized women with psychiatric disorders in Isfahan, Iran. Regular follow-up in psychiatric patients can reduce the incidence of oral lesions and dental caries, or help in their earlier diagnosis and better treatment.","PeriodicalId":20805,"journal":{"name":"Qom Univ Med Sci J","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76974933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-01DOI: 10.32598/qums.16.4.2568.1
M. Shabani, Zahra Taheri Kharameh
Background and Objectives Identification of the risk factors for falls to prevent the risk of fall and reduce the related costs in older adults is necessary. This study aims to translate and determine the validity and reliability of the Persian version of the self-rated fall risk questionnaire (FRQ) for Iranian older adults. Methods In this methodological study, participants were 60 older people who were selected from the Retirement Center in Qom, Iran in 2021 using a convenience sampling method. For translation, the backward/forward technique was used. Then, content validity, face validity, and construct validity were evaluated. To evaluate the construct validity, the known-groups validity (comparsion of groups with and without a history of fall), convergent and divergent validity were used. Reliability was determined by assessing internal consistency. Results The results of known-groups comparison showed that the mean score of FRQ in older people with a history of fall was higher than in older people without a history of fall. The significant correlation of the score of FRQ with the scores of timed up & go test (r= 0.428, P<0.001), and 30-second chair stand test (r=-0.333, P<0.01) confirmed the convergent and divergent validity, respectively. The Kuder-Richardson coefficient (0.624) confirmed the internal consistency of the Persian FRQ. Conclusion The Persian version of the self-rated FRQ has satisfactory psychometric properties. It can be used to measure the risk factors of fall in fall prevention interventions for Iranian older adults.
背景和目的确定老年人跌倒的危险因素以预防跌倒风险并降低相关费用是必要的。本研究旨在翻译并确定波斯语版伊朗老年人自评跌倒风险问卷(FRQ)的效度和信度。在本方法学研究中，参与者是2021年从伊朗库姆退休中心选择的60名老年人，采用方便抽样方法。在翻译时，使用了向后/向前的技巧。然后评估内容效度、面孔效度和构念效度。为了评估构念效度，使用了已知群体效度(有和没有跌倒史的群体的比较)、收敛效度和发散效度。通过评估内部一致性来确定信度。结果已知组比较结果显示，有跌倒史的老年人FRQ平均得分高于无跌倒史的老年人。FRQ得分与time up & go测试得分呈显著相关(r= 0.428, P<0.001)，与30秒椅站测试得分呈显著相关(r=-0.333, P<0.01)，分别证实了收敛效度和发散效度。库德-理查德森系数(0.624)证实了波斯FRQ的内部一致性。结论波斯语版自评FRQ具有满意的心理测量学性质。它可以用来衡量伊朗老年人跌倒预防干预措施中跌倒的危险因素。
{"title":"Psychometric Evaluation of the Persian Version of the Self-rated Fall Risk Questionnaire for Iranian Older Adults","authors":"M. Shabani, Zahra Taheri Kharameh","doi":"10.32598/qums.16.4.2568.1","DOIUrl":"https://doi.org/10.32598/qums.16.4.2568.1","url":null,"abstract":"Background and Objectives Identification of the risk factors for falls to prevent the risk of fall and reduce the related costs in older adults is necessary. This study aims to translate and determine the validity and reliability of the Persian version of the self-rated fall risk questionnaire (FRQ) for Iranian older adults. Methods In this methodological study, participants were 60 older people who were selected from the Retirement Center in Qom, Iran in 2021 using a convenience sampling method. For translation, the backward/forward technique was used. Then, content validity, face validity, and construct validity were evaluated. To evaluate the construct validity, the known-groups validity (comparsion of groups with and without a history of fall), convergent and divergent validity were used. Reliability was determined by assessing internal consistency. Results The results of known-groups comparison showed that the mean score of FRQ in older people with a history of fall was higher than in older people without a history of fall. The significant correlation of the score of FRQ with the scores of timed up & go test (r= 0.428, P<0.001), and 30-second chair stand test (r=-0.333, P<0.01) confirmed the convergent and divergent validity, respectively. The Kuder-Richardson coefficient (0.624) confirmed the internal consistency of the Persian FRQ. Conclusion The Persian version of the self-rated FRQ has satisfactory psychometric properties. It can be used to measure the risk factors of fall in fall prevention interventions for Iranian older adults.","PeriodicalId":20805,"journal":{"name":"Qom Univ Med Sci J","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90459215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Z. Jafari, H. Bardania, M. Jafari Barmak, Yaser Mahmoudi Mourderaz, N. Roustaei, Mohammad Sharif Talebianpoor, E. Panahi kokhdan, S. Khoramrooz
Background and Objectives: Regarding the important role of Staphylococcus aureus in burn wound infection, the present study aims to investigate of the effect of Polycaprolactone (PCL) scaffold containing Myrtus communis extract and silver nanoparticles on the healing of burn wound infections induced by Methicillin-Resistant Staphylococcus Aureus (MRSA) in rats. Methods: In this experimental study, 42 male Wistar rats were divided into seven groups of 6. After anesthesia, second-degree burns on the back of the rats’ necks were created and MRSA was then injected into the wound area. The rats’ wounds were treated daily with nanofiber PCL containing Myrtus communis extract and silver nanoparticles. Antimicrobial properties, wound healing percentage, wound area, malondialdehyde and nitric oxide levels, and total antioxidant capacity were measured. Data were analyzed in GraphPad software using Tukey’s test and ANOVA. Results: The wound area measurement showed the better effects on would healing in the groups treated by PCL+Myrtus communis extract and PCL+Myrtus communis extract+silver nanoparticles compared other groups. In bacteriological studies, the groups treated by PCL+Myrtus communis extract and PCL+Myrtus communis extract+silver nanoparticle showed more reduced bacterial growth compared to the PCL alone and positive control groups. Moreover, biochemical tests showed a decrease in malondialdehyde and nitric oxide levels in rats treated by PCL+Myrtus communis extract compared to other groups. Conclusion: Myrtus communis extract and silver nanoparticles can cause changes in PCL properties, which have an important role in reducing the time required for wound healing and in preventing the progression of MRSA-induced wound infection
{"title":"Effect of Polycaprolactone Scaffold Containing Myrtus Communis Extract and Silver Nanoparticles on the Burn Wound Infection Induced by Methicillinresistant Staphylococcus Aureus in Rats","authors":"Z. Jafari, H. Bardania, M. Jafari Barmak, Yaser Mahmoudi Mourderaz, N. Roustaei, Mohammad Sharif Talebianpoor, E. Panahi kokhdan, S. Khoramrooz","doi":"10.32598/qums.16.4.2445","DOIUrl":"https://doi.org/10.32598/qums.16.4.2445","url":null,"abstract":"Background and Objectives: Regarding the important role of Staphylococcus aureus in burn wound infection, the present study aims to investigate of the effect of Polycaprolactone (PCL) scaffold containing Myrtus communis extract and silver nanoparticles on the healing of burn wound infections induced by Methicillin-Resistant Staphylococcus Aureus (MRSA) in rats. Methods: In this experimental study, 42 male Wistar rats were divided into seven groups of 6. After anesthesia, second-degree burns on the back of the rats’ necks were created and MRSA was then injected into the wound area. The rats’ wounds were treated daily with nanofiber PCL containing Myrtus communis extract and silver nanoparticles. Antimicrobial properties, wound healing percentage, wound area, malondialdehyde and nitric oxide levels, and total antioxidant capacity were measured. Data were analyzed in GraphPad software using Tukey’s test and ANOVA. Results: The wound area measurement showed the better effects on would healing in the groups treated by PCL+Myrtus communis extract and PCL+Myrtus communis extract+silver nanoparticles compared other groups. In bacteriological studies, the groups treated by PCL+Myrtus communis extract and PCL+Myrtus communis extract+silver nanoparticle showed more reduced bacterial growth compared to the PCL alone and positive control groups. Moreover, biochemical tests showed a decrease in malondialdehyde and nitric oxide levels in rats treated by PCL+Myrtus communis extract compared to other groups. Conclusion: Myrtus communis extract and silver nanoparticles can cause changes in PCL properties, which have an important role in reducing the time required for wound healing and in preventing the progression of MRSA-induced wound infection","PeriodicalId":20805,"journal":{"name":"Qom Univ Med Sci J","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89272847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-01DOI: 10.32598/qums.16.4.2625.1
Ali Amirhosseini, Meysam Shafiee Rudposhti, H. Shirazi, Hossein Jannatifar
Background and Objectives: Public-private partnerships (PPPs) are among the interesting topics for scholars, policymakers and managers in various fields, including health. The purpose of this study is to design a model for the development of PPP in the health system of Iran. Methods: This is a qualitative study using a Meta-Synthesis approach. The data were collected by reviewing articles related to the literature which were searched in valid national and international databases. Then, using the opinions of a panel of experts, the qualitative findings extracted from the articles were synthesized to finally discover new concepts. Results: Out of 217 articles extracted, 27 final articles were selected and 66 initial codes were extracted. According to experts, the final results include 3 main dimensions and 12 Components: public sector with Components (organizational and institutional, Administrative and social, legal and regulatory, structural and contextual), private sector with Components (economic and financial, Banking and inflation, technical and specialized, Technology and equipment, legal and contractual) and the charity sector with Components (acceptability and effectiveness, awareness and confidence building, communication and interaction). Conclusion: The present study provides a new model and perspective on how to develop PPP in the health system of Iran. Based on this model, the managers of public, private and charity sectors can improve the health system of the country by using the huge economic, social and cultural capacities of society.
{"title":"A Model for the Development of Public-private Partnerships in the Iranian Health System Using a Meta-Synthesis Approach","authors":"Ali Amirhosseini, Meysam Shafiee Rudposhti, H. Shirazi, Hossein Jannatifar","doi":"10.32598/qums.16.4.2625.1","DOIUrl":"https://doi.org/10.32598/qums.16.4.2625.1","url":null,"abstract":"Background and Objectives: Public-private partnerships (PPPs) are among the interesting topics for scholars, policymakers and managers in various fields, including health. The purpose of this study is to design a model for the development of PPP in the health system of Iran. Methods: This is a qualitative study using a Meta-Synthesis approach. The data were collected by reviewing articles related to the literature which were searched in valid national and international databases. Then, using the opinions of a panel of experts, the qualitative findings extracted from the articles were synthesized to finally discover new concepts. Results: Out of 217 articles extracted, 27 final articles were selected and 66 initial codes were extracted. According to experts, the final results include 3 main dimensions and 12 Components: public sector with Components (organizational and institutional, Administrative and social, legal and regulatory, structural and contextual), private sector with Components (economic and financial, Banking and inflation, technical and specialized, Technology and equipment, legal and contractual) and the charity sector with Components (acceptability and effectiveness, awareness and confidence building, communication and interaction). Conclusion: The present study provides a new model and perspective on how to develop PPP in the health system of Iran. Based on this model, the managers of public, private and charity sectors can improve the health system of the country by using the huge economic, social and cultural capacities of society.","PeriodicalId":20805,"journal":{"name":"Qom Univ Med Sci J","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83184362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-01DOI: 10.32598/qums.16.4.2582.1
Abdulaziz Jamshidzehi, M. Ghalehbandi, Fatemeh Kashaninasab, E. Shirazi
Background and Objectives: Sleep is a complex biological process. Early insomnia is one of the most common problems among young people. This study aims to investigate the sleep-wake pattern of adolescents in Makran region of Sistan and Baluchestan province, Iran Methods: In this descriptive study, 530 high school students in Makran region of Sistan Baluchestan province (three main cities of Saravan, Iranshahr, Chabahar) in the academic year 2019-2021 were selected by a multi-stage sampling method. They completed a demographic form and the morningness-eveningness questionnaire (MEQ). Data were analyzed in SPSS softwareو version 21 software using independent t-test and ANOVA. Results: The students had moderate circadian rhythm, but sleep preferences were reported in these students mostly among boys. The preferred pattern of students in Iranshahr, Saravan and Chabahar cities was the sleep preference. The wake preference, sleep preference, and peak performance preference of students in Iranshahr were lower than in Saravan and Chabahar cities. Conclusion: The sleep-wake pattern of adolescent students in Makran region of Sistan Baluchestan province is at a moderate level, and all students prefer the sleep pattern over other patterns. It is recommended that the circadian rhythms of these students should be investigated and the necessary measures should be taken to inform their parents and adjust the school and home schedule so that the students have better sleep.
{"title":"Sleep-Wake Pattern of Adolescents in Makran Region of Sistan and Baluchestan Province, Iran","authors":"Abdulaziz Jamshidzehi, M. Ghalehbandi, Fatemeh Kashaninasab, E. Shirazi","doi":"10.32598/qums.16.4.2582.1","DOIUrl":"https://doi.org/10.32598/qums.16.4.2582.1","url":null,"abstract":"Background and Objectives: Sleep is a complex biological process. Early insomnia is one of the most common problems among young people. This study aims to investigate the sleep-wake pattern of adolescents in Makran region of Sistan and Baluchestan province, Iran Methods: In this descriptive study, 530 high school students in Makran region of Sistan Baluchestan province (three main cities of Saravan, Iranshahr, Chabahar) in the academic year 2019-2021 were selected by a multi-stage sampling method. They completed a demographic form and the morningness-eveningness questionnaire (MEQ). Data were analyzed in SPSS softwareو version 21 software using independent t-test and ANOVA. Results: The students had moderate circadian rhythm, but sleep preferences were reported in these students mostly among boys. The preferred pattern of students in Iranshahr, Saravan and Chabahar cities was the sleep preference. The wake preference, sleep preference, and peak performance preference of students in Iranshahr were lower than in Saravan and Chabahar cities. Conclusion: The sleep-wake pattern of adolescent students in Makran region of Sistan Baluchestan province is at a moderate level, and all students prefer the sleep pattern over other patterns. It is recommended that the circadian rhythms of these students should be investigated and the necessary measures should be taken to inform their parents and adjust the school and home schedule so that the students have better sleep.","PeriodicalId":20805,"journal":{"name":"Qom Univ Med Sci J","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76699813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-01DOI: 10.32598/qums.16.4.2570.2
Roza Abdellahzadeh, M. Maroufi
Background and Objectives: This study aims to predict the improvement in the symptoms of generalized anxiety disorder (GAD) based on distress tolerance, tolerance of uncertainty, and cognitive avoidance. Methods: This is a descriptive correlational study. Participants were 129 patients with GAD referred to medical centers in Isfahan, Iran, who were selected by a sequential sampling method. Data collection tools included the 7-item GAD questionnaire, distress tolerance scale of Simons and Gaher, Intolerance of Uncertainty scale and cognitive avoidance questionnaire of Sexton and Dugas. Pearson correlation test and stepwise regression analysis were used to analyze the data in SPSS software, version 26. Results: The results showed that the improvement of GAD symptoms had a positive significant relationship with distress tolerance (P=0.01) and a negative significant relationship with intolerance of uncertainty (P<0.001). However, there was no significant relationship between improvement of GAD and cognitive avoidance (P>0.05). Conclusion: The increase of distress tolerance and uncertainty tolerance can relive GAD symptoms. The cognitive avoidance variable had no effect on its improvement.
背景与目的:本研究旨在预测基于痛苦耐受性、不确定性耐受性和认知回避的广泛性焦虑障碍(GAD)症状的改善。方法:采用描述性相关研究。参与者是129名转介到伊朗伊斯法罕医疗中心的广泛性焦虑症患者，他们是通过顺序抽样方法选择的。数据收集工具包括7项GAD问卷、Simons and Gaher的痛苦耐受量表、Sexton and Dugas的不确定性耐受量表和认知回避量表。在SPSS软件26版中采用Pearson相关检验和逐步回归分析对数据进行分析。结果:GAD症状的改善与痛苦耐受性呈正相关(P=0.01)，与不确定性耐受性呈负相关(P0.05)。结论:苦恼耐受性和不确定性耐受性的增加可以缓解GAD症状。认知回避变量对其改善无影响。
{"title":"Predicting the Improvement of Generalized Anxiety Disorder based on Distress Tolerance, Tolerance of Uncertainty, and Cognitive Avoidance","authors":"Roza Abdellahzadeh, M. Maroufi","doi":"10.32598/qums.16.4.2570.2","DOIUrl":"https://doi.org/10.32598/qums.16.4.2570.2","url":null,"abstract":"Background and Objectives: This study aims to predict the improvement in the symptoms of generalized anxiety disorder (GAD) based on distress tolerance, tolerance of uncertainty, and cognitive avoidance. Methods: This is a descriptive correlational study. Participants were 129 patients with GAD referred to medical centers in Isfahan, Iran, who were selected by a sequential sampling method. Data collection tools included the 7-item GAD questionnaire, distress tolerance scale of Simons and Gaher, Intolerance of Uncertainty scale and cognitive avoidance questionnaire of Sexton and Dugas. Pearson correlation test and stepwise regression analysis were used to analyze the data in SPSS software, version 26. Results: The results showed that the improvement of GAD symptoms had a positive significant relationship with distress tolerance (P=0.01) and a negative significant relationship with intolerance of uncertainty (P<0.001). However, there was no significant relationship between improvement of GAD and cognitive avoidance (P>0.05). Conclusion: The increase of distress tolerance and uncertainty tolerance can relive GAD symptoms. The cognitive avoidance variable had no effect on its improvement.","PeriodicalId":20805,"journal":{"name":"Qom Univ Med Sci J","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85450448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-01DOI: 10.32598/qums.16.4.2573.1
Amir Delshad, F. Salimi, Nasrin Heydariyeh, Shima Ababzadeh
Background and Objectives: Cadmium (Cd) can induce lipid peroxidation, increase malondialdehyde (MDA), and reduce total oxidative capacity (TAC) in the testis by producing free radicals and, as a result, cause infertility. This study aims to determine the effect of a period of endurance exercise on MDA levels and TAC of testicular tissue in adult male rats with infertility induced by cadmium chloride. Methods: In this experimental study, 32 healthy adult male Wistar rats weighing 250±30 g and aged 12 weeks were used, which were randomly divided into four groups of control (n=8), exercise (n=8), Cd (n=8), and Cd+exercise (n=8). The endurance exercise program was presented at five sessions per week for 5 weeks. Data were analyzed in SPSS software, version 24 using one-way analysis of variance and by the Least Significant Difference post hoc test. The significance level was set at 0.05. Results: The MDA and TAC in the exercise group were increased significantly compared to the control group (P<0.05), indicating that moderate-intensity endurance exercise significantly increased the TAC and MDA of testicular tissue in Cd-induced infertility. Cd increased oxidative stress markers and reduced antioxidant enzymes. Moderate-intensity endurance exercise significantly increased the antioxidant enzymes. Conclusion: Given the effects of moderate-intensity endurance exercise in rats with Cd-induced infertility, it can be said that these exercises can make the body more resistant to oxidative stress products.
{"title":"Effect of Endurance Exercise on Lipid Peroxidation Level and Total Antioxidant Capacity of Testicular Tissue in Adult Male Rats With Cadmium-induced Infertility","authors":"Amir Delshad, F. Salimi, Nasrin Heydariyeh, Shima Ababzadeh","doi":"10.32598/qums.16.4.2573.1","DOIUrl":"https://doi.org/10.32598/qums.16.4.2573.1","url":null,"abstract":"Background and Objectives: Cadmium (Cd) can induce lipid peroxidation, increase malondialdehyde (MDA), and reduce total oxidative capacity (TAC) in the testis by producing free radicals and, as a result, cause infertility. This study aims to determine the effect of a period of endurance exercise on MDA levels and TAC of testicular tissue in adult male rats with infertility induced by cadmium chloride. Methods: In this experimental study, 32 healthy adult male Wistar rats weighing 250±30 g and aged 12 weeks were used, which were randomly divided into four groups of control (n=8), exercise (n=8), Cd (n=8), and Cd+exercise (n=8). The endurance exercise program was presented at five sessions per week for 5 weeks. Data were analyzed in SPSS software, version 24 using one-way analysis of variance and by the Least Significant Difference post hoc test. The significance level was set at 0.05. Results: The MDA and TAC in the exercise group were increased significantly compared to the control group (P<0.05), indicating that moderate-intensity endurance exercise significantly increased the TAC and MDA of testicular tissue in Cd-induced infertility. Cd increased oxidative stress markers and reduced antioxidant enzymes. Moderate-intensity endurance exercise significantly increased the antioxidant enzymes. Conclusion: Given the effects of moderate-intensity endurance exercise in rats with Cd-induced infertility, it can be said that these exercises can make the body more resistant to oxidative stress products.","PeriodicalId":20805,"journal":{"name":"Qom Univ Med Sci J","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86175124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-04-01DOI: 10.32598/qums.16.1.1464.2
Meysam Khodabandehloo, M. Gaeeni, A. Rahbar, A. Hamta
Background and Objectives: The quality of life (QoL) of the elderly can be declined by several factors. Social capital is one of the effective factors for improving the QoL. This study aims to determine the relationship between social capital and QoL in the elderly hospitalized due to traumatic events. Methods: This is a descriptive-correlational study. The study population consists of all older patients aged 65 years and higher admitted to selected hospitals in Qom, Iran from September 2019 to September 2020 due to experiencing traumatic events. of these, 330 were selected using a non-probability sequential sampling method. Data collection tools were Onyx and Bullen’s social capital questionnaire, the Leiden-Padua quality of life questionnaire, and a demographic checklist. Data were analyzed in SPSS v. 26 software using descriptive statistics and statistical tests including Spearman correlation test, Mann-Whitney U test, Kruskal-Wallis test, and multivariate regression analysis. The significance level was set at 0.05. Results: The mean age of participants was 70±4.6 years; 49% were male and 51% were female. The mean scores of social capital and quality of life were 67.6±13.5 and 51.6±17.4, respectively. A positive and significant correlation was observed between social capital and quality of life (r=0.719, P<0.05). Social capital had a significant relationship with marital status (P=0.000), place of residence (P=0.001), insurance coverage (P=0.000) and level of education (P=0.000). Conclusion: Social capital has a relationship with the quality of life in the elderly experiencing traumatic events. For successful aging and to anticipate its prerequisites, the strengthening and improvement of social capital is important.
背景与目的:老年人的生活质量(QoL)可因多种因素而下降。社会资本是提高生活质量的有效因素之一。本研究旨在探讨创伤性事件住院老年人社会资本与生活质量的关系。方法:采用描述性相关研究。研究人群包括2019年9月至2020年9月期间因经历创伤事件而在伊朗库姆选定医院住院的所有65岁及以上的老年患者。其中，采用非概率序贯抽样方法选取330例。数据收集工具是Onyx和Bullen的社会资本问卷、leden - padua生活质量问卷和人口统计清单。数据采用SPSS v. 26软件进行描述性统计和Spearman相关检验、Mann-Whitney U检验、Kruskal-Wallis检验、多元回归分析等统计检验。显著性水平设为0.05。结果:参与者平均年龄70±4.6岁;49%为男性，51%为女性。社会资本和生活质量的平均得分分别为67.6±13.5分和51.6±17.4分。社会资本与生活质量呈显著正相关(r=0.719, P<0.05)。社会资本与婚姻状况(P=0.000)、居住地(P=0.001)、保险覆盖率(P=0.000)和受教育程度(P=0.000)有显著关系。结论:社会资本对创伤性事件老年人的生活质量有影响。社会资本的加强和完善对于老龄的成功实现和预测其先决条件具有重要意义。
{"title":"Relationship Between Social Capital and Quality of Life (QoL) Among the Elderly Patients Experienced Traumatic Events","authors":"Meysam Khodabandehloo, M. Gaeeni, A. Rahbar, A. Hamta","doi":"10.32598/qums.16.1.1464.2","DOIUrl":"https://doi.org/10.32598/qums.16.1.1464.2","url":null,"abstract":"Background and Objectives: The quality of life (QoL) of the elderly can be declined by several factors. Social capital is one of the effective factors for improving the QoL. This study aims to determine the relationship between social capital and QoL in the elderly hospitalized due to traumatic events. Methods: This is a descriptive-correlational study. The study population consists of all older patients aged 65 years and higher admitted to selected hospitals in Qom, Iran from September 2019 to September 2020 due to experiencing traumatic events. of these, 330 were selected using a non-probability sequential sampling method. Data collection tools were Onyx and Bullen’s social capital questionnaire, the Leiden-Padua quality of life questionnaire, and a demographic checklist. Data were analyzed in SPSS v. 26 software using descriptive statistics and statistical tests including Spearman correlation test, Mann-Whitney U test, Kruskal-Wallis test, and multivariate regression analysis. The significance level was set at 0.05. Results: The mean age of participants was 70±4.6 years; 49% were male and 51% were female. The mean scores of social capital and quality of life were 67.6±13.5 and 51.6±17.4, respectively. A positive and significant correlation was observed between social capital and quality of life (r=0.719, P<0.05). Social capital had a significant relationship with marital status (P=0.000), place of residence (P=0.001), insurance coverage (P=0.000) and level of education (P=0.000). Conclusion: Social capital has a relationship with the quality of life in the elderly experiencing traumatic events. For successful aging and to anticipate its prerequisites, the strengthening and improvement of social capital is important.","PeriodicalId":20805,"journal":{"name":"Qom Univ Med Sci J","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90881872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-04-01DOI: 10.32598/qums.16.1.152.4
M. Gaeeni, Z. Khalajinia, A. Hamta, Tahereh Seddighia
Background and Objectives: Learning styles can show changes in how a learner receives and interacts with the environment. Since teaching and improving the current situation for students to learn in clinic settings is one of the tasks of medical education centers, the present study aims to determine the learning styles in clinical education among students of Qom University of Medical Sciences (QUMS). Methods: This descriptive cross-sectional study was conducted in 2020 on 308 students of QUMS from faculties of Medicine, Nursing, Midwifery and Paramedical Sciences who were selected by a stratified random sampling method in two groups of apprenticeship and internship. The data collection tool was the Kolb Learning Styles Inventory. Data were analyzed using descriptive statistics and chi-square test. Results: The mean age of students was 23.7±4.3 years; 54.9% were female and 45.1% were male; 64% were undergraduate students and 36% were doctoral students. It was found that 48.1% of students had an assimilating learning style, 24.7% had a diverging learning style, 17.5% had a converging learning style and 9.7% had an accommodating learning style. There was a significant difference between learning styles in terms of the field of study (P=0.03), but not in terms of gender, educational level, marital status and academic year (first-year and final-year students). Conclusion: Most of students in QUMS have assimilating and diverging learning styles; therefore, providing learning environments appropriate to these styles is important for their better learning and gaining the necessary capabilities in future educational and professional environments.
{"title":"Investigating the Learning Styles in Clinical Training Among Students of Qom University of Medical Sciences, Iran","authors":"M. Gaeeni, Z. Khalajinia, A. Hamta, Tahereh Seddighia","doi":"10.32598/qums.16.1.152.4","DOIUrl":"https://doi.org/10.32598/qums.16.1.152.4","url":null,"abstract":"Background and Objectives: Learning styles can show changes in how a learner receives and interacts with the environment. Since teaching and improving the current situation for students to learn in clinic settings is one of the tasks of medical education centers, the present study aims to determine the learning styles in clinical education among students of Qom University of Medical Sciences (QUMS). Methods: This descriptive cross-sectional study was conducted in 2020 on 308 students of QUMS from faculties of Medicine, Nursing, Midwifery and Paramedical Sciences who were selected by a stratified random sampling method in two groups of apprenticeship and internship. The data collection tool was the Kolb Learning Styles Inventory. Data were analyzed using descriptive statistics and chi-square test. Results: The mean age of students was 23.7±4.3 years; 54.9% were female and 45.1% were male; 64% were undergraduate students and 36% were doctoral students. It was found that 48.1% of students had an assimilating learning style, 24.7% had a diverging learning style, 17.5% had a converging learning style and 9.7% had an accommodating learning style. There was a significant difference between learning styles in terms of the field of study (P=0.03), but not in terms of gender, educational level, marital status and academic year (first-year and final-year students). Conclusion: Most of students in QUMS have assimilating and diverging learning styles; therefore, providing learning environments appropriate to these styles is important for their better learning and gaining the necessary capabilities in future educational and professional environments.","PeriodicalId":20805,"journal":{"name":"Qom Univ Med Sci J","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76411121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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