Pub Date : 2023-01-01DOI: 10.32598/qums.16.6.2600.2
Maryam Nilghaz, Masoumeh Mahdavi-Ourtakand, F. Noorbakhsh
Background and Objectives: Psoriasis is a chronic and inflammatory skin disease, which is has no definitive cure. Several microbial agents have been identified that have a role in the exacerbation of psoriasis, one of which is Staphylococcus aureus. Increased Methicillin-resistance Staphylococcus aureus (MRSA) strains is a major problem worldwide. This study aims to evaluate the antibacterial effect of Cinnamomum zeylanicum essential oil on MRSA strains isolated from skin lesions in patients with psoriasis. Methods: In this study, participants were 140 patients with psoriasis referred to the dermatology and rheumatology clinic of Shariati Hospital in Tehran, Iran. Diagnostic tests including gram staining, catalase test, tube coagulase test, mannitol fermentation test, and deoxyribonuclease test were performed. To identify the phenotype of MRSA strains, methicillin susceptibility testing was performed using cefoxitin by disk diffusion method. The antimicrobial activity of Cinnamomum zeylanicum essential oil was investigated by broth microdilution method and its minimum inhibitory concentration against MRSA strains was calculated. Results: Of 140 patients, 43.57% had infection with Staphylococcus aureus and 14.28% had MRSA infection. There was no significant relationship between gender, age and sampling area in patients with MRSA infection. The results showed that Cinnamomum zeylanicum essential oil had antimicrobial effects on MRSA strains. Conclusion: The Cinnamomum zeylanicum essential oil can be a suitable alternative to antibiotics for the control and treatment of skin infections caused by Staphylococcus aureus.
{"title":"Antibacterial Activity of Cinnamomum Zeylanicum Essential Oil Against Methicillin-resistant Staphylococcus Aureus Strains Isolated From Skin Lesions In Patients With Psoriasis","authors":"Maryam Nilghaz, Masoumeh Mahdavi-Ourtakand, F. Noorbakhsh","doi":"10.32598/qums.16.6.2600.2","DOIUrl":"https://doi.org/10.32598/qums.16.6.2600.2","url":null,"abstract":"Background and Objectives: Psoriasis is a chronic and inflammatory skin disease, which is has no definitive cure. Several microbial agents have been identified that have a role in the exacerbation of psoriasis, one of which is Staphylococcus aureus. Increased Methicillin-resistance Staphylococcus aureus (MRSA) strains is a major problem worldwide. This study aims to evaluate the antibacterial effect of Cinnamomum zeylanicum essential oil on MRSA strains isolated from skin lesions in patients with psoriasis. Methods: In this study, participants were 140 patients with psoriasis referred to the dermatology and rheumatology clinic of Shariati Hospital in Tehran, Iran. Diagnostic tests including gram staining, catalase test, tube coagulase test, mannitol fermentation test, and deoxyribonuclease test were performed. To identify the phenotype of MRSA strains, methicillin susceptibility testing was performed using cefoxitin by disk diffusion method. The antimicrobial activity of Cinnamomum zeylanicum essential oil was investigated by broth microdilution method and its minimum inhibitory concentration against MRSA strains was calculated. Results: Of 140 patients, 43.57% had infection with Staphylococcus aureus and 14.28% had MRSA infection. There was no significant relationship between gender, age and sampling area in patients with MRSA infection. The results showed that Cinnamomum zeylanicum essential oil had antimicrobial effects on MRSA strains. Conclusion: The Cinnamomum zeylanicum essential oil can be a suitable alternative to antibiotics for the control and treatment of skin infections caused by Staphylococcus aureus.","PeriodicalId":20805,"journal":{"name":"Qom Univ Med Sci J","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89343325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.32598/qums.16.6.2518.1
H. Motaarefi, S. Sakhaei, Mahsa Ashrafi, Sorayya Zinalpoor, Homed Gholizadgougjehyaran
Introduction: Educating nursing students as future and front-line nurses of patient care is very important to ensure that they have the appropriate knowledge and skills in infection prevention and control. Therefore, the present study was conducted with the aim of the effect of teaching standard precautions on the knowledge and practice of nursing students. Materials and Methods: This quasi-experimental study was performed on 70 final year nursing students and was randomly assigned to the intervention and control groups. Criteria for data collection tools included demographic questionnaire and Kirk Patrick evaluation model. For the intervention group, a training program was implemented based on the crack patrick model and for the control group, an educational booklet was given to students. After the training program, its effectiveness was evaluated in four levels (reaction, learning, behavior, results) of Kirk Patrick model. To assess the amount of learning using the researcher-made test before and after the test one week after training, the amount of learning was measured. To evaluate the performance, an observational checklist was used which consists of 8 sections and a total of 66. Whether or not each of the 66 functions was performed by the research units, by the researcher on different days imperceptibly before and one month after the intervention and The checklist was completed. Finally, after collecting statistical data, the results were analyzed using descriptive and inferential statistics. Results: The findings of this study show that the average learning score of nursing students after the educational program based on the Kirk Patrick model increased significantly and also the average performance score of nursing students after the educational program increased significantly. Discussion & Conclusion: The results indicate the effectiveness of the course held for nursing students and it seems that Kirk Patrick model can be a suitable way to evaluate the effectiveness of health education
{"title":"Effect of Teaching Standard Precautions Based on Kirkpatrick’s Model on the Knowledge and Practice of Nursing Students","authors":"H. Motaarefi, S. Sakhaei, Mahsa Ashrafi, Sorayya Zinalpoor, Homed Gholizadgougjehyaran","doi":"10.32598/qums.16.6.2518.1","DOIUrl":"https://doi.org/10.32598/qums.16.6.2518.1","url":null,"abstract":"Introduction: Educating nursing students as future and front-line nurses of patient care is very important to ensure that they have the appropriate knowledge and skills in infection prevention and control. Therefore, the present study was conducted with the aim of the effect of teaching standard precautions on the knowledge and practice of nursing students. Materials and Methods: This quasi-experimental study was performed on 70 final year nursing students and was randomly assigned to the intervention and control groups. Criteria for data collection tools included demographic questionnaire and Kirk Patrick evaluation model. For the intervention group, a training program was implemented based on the crack patrick model and for the control group, an educational booklet was given to students. After the training program, its effectiveness was evaluated in four levels (reaction, learning, behavior, results) of Kirk Patrick model. To assess the amount of learning using the researcher-made test before and after the test one week after training, the amount of learning was measured. To evaluate the performance, an observational checklist was used which consists of 8 sections and a total of 66. Whether or not each of the 66 functions was performed by the research units, by the researcher on different days imperceptibly before and one month after the intervention and The checklist was completed. Finally, after collecting statistical data, the results were analyzed using descriptive and inferential statistics. Results: The findings of this study show that the average learning score of nursing students after the educational program based on the Kirk Patrick model increased significantly and also the average performance score of nursing students after the educational program increased significantly. Discussion & Conclusion: The results indicate the effectiveness of the course held for nursing students and it seems that Kirk Patrick model can be a suitable way to evaluate the effectiveness of health education","PeriodicalId":20805,"journal":{"name":"Qom Univ Med Sci J","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90791693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.32598/qums.16.10.195.1
Hoda Ahmari Tehran, H. Adeli, Ahmad Kachoie
This article has no abstract.
这篇文章没有摘要。
{"title":"Objective Structured Teaching Exercise: A Method to Improve and Evaluate the Empathy and Communication Skills of Clinical Professors","authors":"Hoda Ahmari Tehran, H. Adeli, Ahmad Kachoie","doi":"10.32598/qums.16.10.195.1","DOIUrl":"https://doi.org/10.32598/qums.16.10.195.1","url":null,"abstract":"This article has no abstract.","PeriodicalId":20805,"journal":{"name":"Qom Univ Med Sci J","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74427297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.32598/qums.16.10.2751.1
M. Zare, Z. Tagharrobi
Background and Objectives: One of the challenges in studies related to measuring patient-reported outcomes (PRO) is the selection of an appropriate measurement tool. In this regard, compliance with standards in design and reporting of psychometric studies is necessity. In addition, researchers should be able to correctly evaluate the methodological quality of psychometric studies. Considering the presentation of the revised forms for the consensus-based standards for the selection of health Measurement instruments (COSMIN) checklist, this study aims to review these checklists. Methods: In this narrative review study, a search was conducted in national and international databases for articles measured the quality of psychometric studies by COSMIN checklist using related keywords in Persian and English with no time limitations. The results are presented in two sections, including the history of COSMIN checklist and the introduction of its revised forms. Results: There are four COSMIN checklists, including the COSMIN Risk of Bias Checklist, the COSMIN Risk of Bias Tool (by focusing on reliability and measurement error), the COSMIN Study Design Checklist, and the COSMIN Reporting Guideline. Conclusion: Considering the increasing number of psychometric studies on the PRO measurement tools, the COSMIN checklists can provide comprehensive indicators for designing, reporting, and evaluating these studies.
{"title":"The Framework of Designing, Reporting, and Evaluating the Methodological Quality for Psychometric Studies: The Revised COSMIN Checklists","authors":"M. Zare, Z. Tagharrobi","doi":"10.32598/qums.16.10.2751.1","DOIUrl":"https://doi.org/10.32598/qums.16.10.2751.1","url":null,"abstract":"Background and Objectives: One of the challenges in studies related to measuring patient-reported outcomes (PRO) is the selection of an appropriate measurement tool. In this regard, compliance with standards in design and reporting of psychometric studies is necessity. In addition, researchers should be able to correctly evaluate the methodological quality of psychometric studies. Considering the presentation of the revised forms for the consensus-based standards for the selection of health Measurement instruments (COSMIN) checklist, this study aims to review these checklists. Methods: In this narrative review study, a search was conducted in national and international databases for articles measured the quality of psychometric studies by COSMIN checklist using related keywords in Persian and English with no time limitations. The results are presented in two sections, including the history of COSMIN checklist and the introduction of its revised forms. Results: There are four COSMIN checklists, including the COSMIN Risk of Bias Checklist, the COSMIN Risk of Bias Tool (by focusing on reliability and measurement error), the COSMIN Study Design Checklist, and the COSMIN Reporting Guideline. Conclusion: Considering the increasing number of psychometric studies on the PRO measurement tools, the COSMIN checklists can provide comprehensive indicators for designing, reporting, and evaluating these studies.","PeriodicalId":20805,"journal":{"name":"Qom Univ Med Sci J","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80364311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.32598/qums.16.6.2542.2
N. Hajloo, S. Pourabdol, Mahdi Beyki, A. Rahnejat
Background and Objectives: It is predicted that the negative effects of the novel coronavirus disease 2019 (COVID-19) pandemic will continue. These negative effects are not limited to psychological problems. Serious physiological and economic problems have also been observed. It is important to develop and standardize appropriate tools to assess its different effects. This study aims to investigate the psychometric properties of the Persian version of the COVID-19 Phobia Scale (C19P-S) in Iranian samples. Methods: In this study, participants were people aged 18-60 years in Iran from March to May 2022, who were selected by a convenience sampling method. In order to evaluate the convergent and discriminant validity, the second version of the acceptance and action questionnaire, the brief version of the difficulty in emotion regulation scale, and the fear of COVID‐19 scale were used. The factor structure of the questionnaire was examined by confirmatory factor analysis. Reliability was examined using Cronbach’s alpha coefficient and the test-retest method. The data were analyzed in SPSS version 25 and LISREL version 8.8. Results: The results of confirmatory factor analysis confirmed the four-factor structure the Persian C19P-S. Cronbach’s alpha coefficient for the whole scale was 0.90; for the subscales of psychological, psychological, economic and social factors, it was 0.87, 0.88, 0.89, and 0.91, respectively. In addition, the test-retest reliability with a four-week interval for the whole scale was 0.86; for the subscales of psychological, psychological, economic and social factors, it was 0.83, 0.79, 0.82, and 0.88, respectively. The correlation coefficients indicated the favorable convergent and discriminant validity of the Persian C19P-S (P<0.001). Conclusion: The Persian C19P-S is a reliable and valid scale for measuring coronaphobia in Iranian samp
背景与目的:预计2019年新型冠状病毒病(COVID-19)大流行的负面影响将持续下去。这些负面影响并不局限于心理问题。还观察到严重的生理和经济问题。重要的是开发和标准化适当的工具来评估其不同的影响。本研究旨在调查伊朗样本中波斯版COVID-19恐惧症量表(C19P-S)的心理测量特性。方法:本研究采用方便抽样法，选取2022年3月至5月在伊朗居住的18-60岁人群。采用第二版接受与行动问卷、情绪调节困难程度简易量表和COVID - 19恐惧量表进行收敛效度和判别效度评估。采用验证性因子分析对问卷的因子结构进行检验。信度采用Cronbach’s alpha系数和重测法进行检验。采用SPSS version 25和LISREL version 8.8对数据进行分析。结果:验证性因子分析结果证实了波斯C19P-S的四因子结构。整个量表的Cronbach 's alpha系数为0.90;心理因素、心理因素、经济因素和社会因素的得分分别为0.87、0.88、0.89和0.91。此外，整个量表在四周间隔的重测信度为0.86;心理因素、心理因素、经济因素和社会因素的得分分别为0.83、0.79、0.82和0.88。相关系数显示波斯C19P-S具有良好的收敛效度和判别效度(P<0.001)。结论:波斯C19P-S量表是一种可靠有效的测量伊朗样本冠状病毒恐惧症的量表
{"title":"Psychometric Properties of the Persian Version of the COVID-19 Phobia Scale","authors":"N. Hajloo, S. Pourabdol, Mahdi Beyki, A. Rahnejat","doi":"10.32598/qums.16.6.2542.2","DOIUrl":"https://doi.org/10.32598/qums.16.6.2542.2","url":null,"abstract":"Background and Objectives: It is predicted that the negative effects of the novel coronavirus disease 2019 (COVID-19) pandemic will continue. These negative effects are not limited to psychological problems. Serious physiological and economic problems have also been observed. It is important to develop and standardize appropriate tools to assess its different effects. This study aims to investigate the psychometric properties of the Persian version of the COVID-19 Phobia Scale (C19P-S) in Iranian samples. Methods: In this study, participants were people aged 18-60 years in Iran from March to May 2022, who were selected by a convenience sampling method. In order to evaluate the convergent and discriminant validity, the second version of the acceptance and action questionnaire, the brief version of the difficulty in emotion regulation scale, and the fear of COVID‐19 scale were used. The factor structure of the questionnaire was examined by confirmatory factor analysis. Reliability was examined using Cronbach’s alpha coefficient and the test-retest method. The data were analyzed in SPSS version 25 and LISREL version 8.8. Results: The results of confirmatory factor analysis confirmed the four-factor structure the Persian C19P-S. Cronbach’s alpha coefficient for the whole scale was 0.90; for the subscales of psychological, psychological, economic and social factors, it was 0.87, 0.88, 0.89, and 0.91, respectively. In addition, the test-retest reliability with a four-week interval for the whole scale was 0.86; for the subscales of psychological, psychological, economic and social factors, it was 0.83, 0.79, 0.82, and 0.88, respectively. The correlation coefficients indicated the favorable convergent and discriminant validity of the Persian C19P-S (P<0.001). Conclusion: The Persian C19P-S is a reliable and valid scale for measuring coronaphobia in Iranian samp","PeriodicalId":20805,"journal":{"name":"Qom Univ Med Sci J","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83364540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.32598/qums.16.10.949.9
Leila Ghanbari-Afra, Monireh Ghanbari-afra
Background and Objectives: Occupational stress is one of the most common psychiatric disorders in nurses during the COVID-19 pandemic. The present study aims to investigate the occupational stress level of nurses and its related factors during the COVID-19 pandemic. Methods: This is a systematic review study that was conducted in 2022 by searching for articles in both Persian and English in Web of Science, SID, Scopus, Google Scholar, Cochran, MagIran, IranDoc and PubMed databases without time limit. The used keywords were nurse, Iran, COVID-19, occupational stress, and job stress in Persian and English. Initial search yielded 3860 articles. Of these, 15 articles were finally reviewed. Results: In the reviewed studies, nurses’ occupational stress during the COVID-19 pandemic was at a high level. The highest score was related to the “demands” dimension and the lowest score was related to “the changes” dimension of the health and safety executive questionnaire. Demographic, occupational, and mental factors and quitting job had a significant positive relationship with nurses’ occupational stress, while low rest, job-related affective well-being, organizational commitment, productivity, organizational climate, and knowledge had a significant negative relationship with their occupational stress. Conclusion: The occupational stress of nurses is high during the COVID-19 pandemic. Occupational stress is related to demographic, occupational, psychological, and organizational factors. It is recommended to form committees to monitor nurses’ occupational stress in hospitals.
背景与目的:职业压力是新冠肺炎大流行期间护士最常见的精神障碍之一。本研究旨在了解新冠肺炎大流行期间护士的职业压力水平及其相关因素。方法:这是一项系统综述研究，于2022年在Web of Science、SID、Scopus、Google Scholar、Cochran、MagIran、IranDoc和PubMed数据库中搜索波斯语和英语文章，没有时间限制。使用的关键词是护士、伊朗、COVID-19、职业压力和工作压力，波斯语和英语。最初的搜索产生了3860篇文章。其中15篇文章最终被审稿。结果:在回顾的研究中，新冠肺炎大流行期间护士的职业压力处于较高水平。健康安全执行问卷的“需求”维度得分最高，“变化”维度得分最低。人口、职业、心理因素和离职对护士职业压力有显著的正向影响，低休息、工作相关情感幸福感、组织承诺、生产力、组织氛围和知识对护士职业压力有显著的负向影响。结论:新冠肺炎大流行期间护士职业压力较高。职业压力与人口、职业、心理和组织因素有关。建议成立护士职业压力监测委员会。
{"title":"Occupational Stress of Nurses and its Related Factors During the COVID-19 Pandemic: A Systematic Review","authors":"Leila Ghanbari-Afra, Monireh Ghanbari-afra","doi":"10.32598/qums.16.10.949.9","DOIUrl":"https://doi.org/10.32598/qums.16.10.949.9","url":null,"abstract":"Background and Objectives: Occupational stress is one of the most common psychiatric disorders in nurses during the COVID-19 pandemic. The present study aims to investigate the occupational stress level of nurses and its related factors during the COVID-19 pandemic. Methods: This is a systematic review study that was conducted in 2022 by searching for articles in both Persian and English in Web of Science, SID, Scopus, Google Scholar, Cochran, MagIran, IranDoc and PubMed databases without time limit. The used keywords were nurse, Iran, COVID-19, occupational stress, and job stress in Persian and English. Initial search yielded 3860 articles. Of these, 15 articles were finally reviewed. Results: In the reviewed studies, nurses’ occupational stress during the COVID-19 pandemic was at a high level. The highest score was related to the “demands” dimension and the lowest score was related to “the changes” dimension of the health and safety executive questionnaire. Demographic, occupational, and mental factors and quitting job had a significant positive relationship with nurses’ occupational stress, while low rest, job-related affective well-being, organizational commitment, productivity, organizational climate, and knowledge had a significant negative relationship with their occupational stress. Conclusion: The occupational stress of nurses is high during the COVID-19 pandemic. Occupational stress is related to demographic, occupational, psychological, and organizational factors. It is recommended to form committees to monitor nurses’ occupational stress in hospitals.","PeriodicalId":20805,"journal":{"name":"Qom Univ Med Sci J","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79074044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.32598/qums.16.10.2503.2
Mohammad Sasanipour, S. Shahbazin
Background and Objectives: Today, one of the goals to improve the quality of life (QoL) of the elderly is to achieve successful aging. This study aims to investigate the determinants of successful aging in Tehran, Iran. Methods: This is a quantitative cross-sectional study. Participants were 637 older people over 60 years of age who were collected using a multi-stage cluster sampling method from 22 districts of Tehran, according to the number of older people in each district. Chi-square test and multiple logistic regression were used for analyze the collected data. Results: Prevalence of successful aging in Tehran was 19.6%. The results of multivariable logistic regression analysis showed that younger people and non-smokers had a higher chance of successful aging (Odds ratio=1.8 and 1.9, respectively). Those with elementary/secondary education and further and higher education (respectively with 2.9 rand 3.4 odds ratio) and daily exercise (odds ratio=2.4) had also a higher chance of successful aging. Conclusion: Improving the level of education and improving a healthy lifestyle, including not smoking and doing physical activities, leads to a successful aging, which requires long-term planning and special attention.
{"title":"Determinants of Successful Aging in Tehran, Iran in 2022","authors":"Mohammad Sasanipour, S. Shahbazin","doi":"10.32598/qums.16.10.2503.2","DOIUrl":"https://doi.org/10.32598/qums.16.10.2503.2","url":null,"abstract":"Background and Objectives: Today, one of the goals to improve the quality of life (QoL) of the elderly is to achieve successful aging. This study aims to investigate the determinants of successful aging in Tehran, Iran. Methods: This is a quantitative cross-sectional study. Participants were 637 older people over 60 years of age who were collected using a multi-stage cluster sampling method from 22 districts of Tehran, according to the number of older people in each district. Chi-square test and multiple logistic regression were used for analyze the collected data. Results: Prevalence of successful aging in Tehran was 19.6%. The results of multivariable logistic regression analysis showed that younger people and non-smokers had a higher chance of successful aging (Odds ratio=1.8 and 1.9, respectively). Those with elementary/secondary education and further and higher education (respectively with 2.9 rand 3.4 odds ratio) and daily exercise (odds ratio=2.4) had also a higher chance of successful aging. Conclusion: Improving the level of education and improving a healthy lifestyle, including not smoking and doing physical activities, leads to a successful aging, which requires long-term planning and special attention.","PeriodicalId":20805,"journal":{"name":"Qom Univ Med Sci J","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79603820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-01DOI: 10.32598/qums.16.9.1416.3
Sahar Torki, M. Nezhadali, M. Hedayati
Background and Objectives: Vaspin is a novel adipocytokine. Various studies have shown that vaspin is associated with many types of cancer. This study aims to determine the association of vaspin rs2236242 gene polymorphism with vaspin level in women with papillary thyroid cancer (PTC) and Multinodular goiter (MNG). Methods: In this case-control study participants were 134 women. They were divided into three groups; PTC (n=49), MNG (n=30) and control (n=55). Ten milliliter peripheral blood samples were taken from participants, 5 ml was used for DNA extraction and 5 ml for preparation of serum. The vaspin level was measured by Sandwich ELISA kit. The genotype determination of vaspin rs2236242 polymorphism was done using the tetra primer-amplification refractory mutation system/polymerase chain reaction method. Results: There were no significant difference in serum vaspin level among the three groups. There was no significant association between genotypes of vaspin rs2236242 polymorphism and serum vaspin level in any groups. Logistic regression analysis showed that the difference in the frequency of the genotypes of rs2236242 polymorphism in the MNG group was significant compared to the control group. The TA genotype showed a protective effect against PTC and MNG (P<0.05). Conclusion: There is no significant difference in vaspin level between PTC, MNG and control groups. There is no association between rs2236242 gene polymorphism and serum vaspin level. The TA genotype of rs2236242 has a protective effect against MNG.
{"title":"Association Between Vaspin Gene Polymorphism and Serum Vaspin Level in Women With Papillary Thyroid Cancer and Multinodular Goiter","authors":"Sahar Torki, M. Nezhadali, M. Hedayati","doi":"10.32598/qums.16.9.1416.3","DOIUrl":"https://doi.org/10.32598/qums.16.9.1416.3","url":null,"abstract":"Background and Objectives: Vaspin is a novel adipocytokine. Various studies have shown that vaspin is associated with many types of cancer. This study aims to determine the association of vaspin rs2236242 gene polymorphism with vaspin level in women with papillary thyroid cancer (PTC) and Multinodular goiter (MNG). Methods: In this case-control study participants were 134 women. They were divided into three groups; PTC (n=49), MNG (n=30) and control (n=55). Ten milliliter peripheral blood samples were taken from participants, 5 ml was used for DNA extraction and 5 ml for preparation of serum. The vaspin level was measured by Sandwich ELISA kit. The genotype determination of vaspin rs2236242 polymorphism was done using the tetra primer-amplification refractory mutation system/polymerase chain reaction method. Results: There were no significant difference in serum vaspin level among the three groups. There was no significant association between genotypes of vaspin rs2236242 polymorphism and serum vaspin level in any groups. Logistic regression analysis showed that the difference in the frequency of the genotypes of rs2236242 polymorphism in the MNG group was significant compared to the control group. The TA genotype showed a protective effect against PTC and MNG (P<0.05). Conclusion: There is no significant difference in vaspin level between PTC, MNG and control groups. There is no association between rs2236242 gene polymorphism and serum vaspin level. The TA genotype of rs2236242 has a protective effect against MNG.","PeriodicalId":20805,"journal":{"name":"Qom Univ Med Sci J","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89932376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-01DOI: 10.32598/qums.16.9.1462.9
Yasamin Barakian, A. Mohammadbeigi, Fatemeh Ahmadian, Mohaddeseh Bahrami Khandan
Background and Objectives: The carotid artery calcification (CAC) can be seen in panoramic radiographs that are usually used in dentistry. This study aims to determine the prevalence of CAC in Qom, Iran using panoramic radiographs, and find its related factors. Methods: This is a descriptive cross-sectional study. Panoramic radiographs of 417 patients aged ≥40 years referred to a specialized oral and maxillofacial radiology center in Qom city in 2021 were examined for the presence of CAC and a questionnaire was used to find the related risk factors. The collected data were analyzed in SPSS software, vertion 22 using Chi-square test and t-test. Results: Of 417 participants, 141 (33.8%) were male and 276 (66.2%) were female. The prevalence of CAC was 1.4%. There was a significant association between CAC and history of cardiovascular diseases (P=0.03), but the incidence of CAC had no association with the history of diabetes, smoking, hypertension, cerebrovascular accident, and myocardial infarction (P>0.05). Conclusion: The incidence of CAC is associated with the history of cardiovascular diseases. Further prospective studies with larger sample sizes are recommended.
{"title":"Carotid Artery Calcification in Panoramic Radiography and Related Risk Factors","authors":"Yasamin Barakian, A. Mohammadbeigi, Fatemeh Ahmadian, Mohaddeseh Bahrami Khandan","doi":"10.32598/qums.16.9.1462.9","DOIUrl":"https://doi.org/10.32598/qums.16.9.1462.9","url":null,"abstract":"Background and Objectives: The carotid artery calcification (CAC) can be seen in panoramic radiographs that are usually used in dentistry. This study aims to determine the prevalence of CAC in Qom, Iran using panoramic radiographs, and find its related factors. Methods: This is a descriptive cross-sectional study. Panoramic radiographs of 417 patients aged ≥40 years referred to a specialized oral and maxillofacial radiology center in Qom city in 2021 were examined for the presence of CAC and a questionnaire was used to find the related risk factors. The collected data were analyzed in SPSS software, vertion 22 using Chi-square test and t-test. Results: Of 417 participants, 141 (33.8%) were male and 276 (66.2%) were female. The prevalence of CAC was 1.4%. There was a significant association between CAC and history of cardiovascular diseases (P=0.03), but the incidence of CAC had no association with the history of diabetes, smoking, hypertension, cerebrovascular accident, and myocardial infarction (P>0.05). Conclusion: The incidence of CAC is associated with the history of cardiovascular diseases. Further prospective studies with larger sample sizes are recommended.","PeriodicalId":20805,"journal":{"name":"Qom Univ Med Sci J","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86907133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-01DOI: 10.32598/qums.16.9.2715.1
S. Adib
Background and Objectives: The ability of ovarian stem cells (OSCs) to differentiate into oocyte-like and theca cells may lead to major advances in infertility treatment. However, little is known about the function, growth and differentiation potentials of these cells. In this study, we aim to examine the characteristics of OSCs obtained from newborn rats and assess their ability to differentiate into osteocyte-like and adipocyte-like cells. Methods: In this study, OSCs were isolated from newborn Syrian rats and were then cultured. After the third passage, using the PCR method, the expression of stem cell markers (Sox2, Pou5f, and Nanog) was examined. Their potential to differentiate into osteocyte-like and adipocyte-like cells was examined by Alizarin red and Oil red staining, respectively. Results: The isolated OSCs were adherent and morphologically similar to fibroblast cells, and had the power to multiply. They expressed stem cells markers. In addition, they were able to differentiate into adipocyte-like and osteocyte-like cells 21 days after being placed in the differentiation medium. In the osteocyte-like cells, fat droplets were observed after oil red staining. Conclusion: The OSCs include multipotent stem cells that are able to express markers related to stem cells and can differentiate into osteocyte-like and adipocyte-like cells.
{"title":"Morphology and Molecular Studies and Differentiation Ability of Ovarian Stem Cells in Newborn Syrian Rats","authors":"S. Adib","doi":"10.32598/qums.16.9.2715.1","DOIUrl":"https://doi.org/10.32598/qums.16.9.2715.1","url":null,"abstract":"Background and Objectives: The ability of ovarian stem cells (OSCs) to differentiate into oocyte-like and theca cells may lead to major advances in infertility treatment. However, little is known about the function, growth and differentiation potentials of these cells. In this study, we aim to examine the characteristics of OSCs obtained from newborn rats and assess their ability to differentiate into osteocyte-like and adipocyte-like cells. Methods: In this study, OSCs were isolated from newborn Syrian rats and were then cultured. After the third passage, using the PCR method, the expression of stem cell markers (Sox2, Pou5f, and Nanog) was examined. Their potential to differentiate into osteocyte-like and adipocyte-like cells was examined by Alizarin red and Oil red staining, respectively. Results: The isolated OSCs were adherent and morphologically similar to fibroblast cells, and had the power to multiply. They expressed stem cells markers. In addition, they were able to differentiate into adipocyte-like and osteocyte-like cells 21 days after being placed in the differentiation medium. In the osteocyte-like cells, fat droplets were observed after oil red staining. Conclusion: The OSCs include multipotent stem cells that are able to express markers related to stem cells and can differentiate into osteocyte-like and adipocyte-like cells.","PeriodicalId":20805,"journal":{"name":"Qom Univ Med Sci J","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80792563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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