Face-to-face interactions, via teleconferencing link, are investigated for multidisciplinary medical team (MDT) meetings. Comparison is made between colocated MDT meetings and those held in teleconference. Attitudes towards video changed positively, over a period of 8 months, following participants' experience of teleconferencing. Analysis of display screen use reveals 60% of case discussion time was time spent in face-to-face view with remote sites, contrary to expressed views of its relative unimportance. The value of the video link in MDT meetings, held in teleconference, is found to have higher than expected value
{"title":"Probing the Use and Value of Video for Multi-Disciplinary Medical Teams in Teleconference","authors":"B. Kane, S. Luz","doi":"10.1109/CBMS.2006.131","DOIUrl":"https://doi.org/10.1109/CBMS.2006.131","url":null,"abstract":"Face-to-face interactions, via teleconferencing link, are investigated for multidisciplinary medical team (MDT) meetings. Comparison is made between colocated MDT meetings and those held in teleconference. Attitudes towards video changed positively, over a period of 8 months, following participants' experience of teleconferencing. Analysis of display screen use reveals 60% of case discussion time was time spent in face-to-face view with remote sites, contrary to expressed views of its relative unimportance. The value of the video link in MDT meetings, held in teleconference, is found to have higher than expected value","PeriodicalId":208693,"journal":{"name":"19th IEEE Symposium on Computer-Based Medical Systems (CBMS'06)","volume":"116 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115673540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In this paper, we report our experience in the development of a system for automatic acquisition of immuno-fluorescence assay (IFA) images. We focus on two basic issues. Firstly, we determine an autofocus function that can deal with photobleaching, a physical phenomenon affecting automatic acquisition of IFA images, and present a set of experiments on real images that confirm its effectiveness. Secondly, we discuss if the physicians may reliably use digital IFA images in place of direct microscope observations to carry out the diagnosis. In this respect, we present the results of a preliminary experiment where physicians perform the diagnosis on a set of images both by looking directly to them at the fluorescence microscope and by looking at digital images on the screen of a workstation
{"title":"Automatic Acquisition of Immunofluorescence Images: Algorithms and Evaluation","authors":"P. Soda, A. Rigon, A. Afeltra, G. Iannello","doi":"10.1109/CBMS.2006.53","DOIUrl":"https://doi.org/10.1109/CBMS.2006.53","url":null,"abstract":"In this paper, we report our experience in the development of a system for automatic acquisition of immuno-fluorescence assay (IFA) images. We focus on two basic issues. Firstly, we determine an autofocus function that can deal with photobleaching, a physical phenomenon affecting automatic acquisition of IFA images, and present a set of experiments on real images that confirm its effectiveness. Secondly, we discuss if the physicians may reliably use digital IFA images in place of direct microscope observations to carry out the diagnosis. In this respect, we present the results of a preliminary experiment where physicians perform the diagnosis on a set of images both by looking directly to them at the fluorescence microscope and by looking at digital images on the screen of a workstation","PeriodicalId":208693,"journal":{"name":"19th IEEE Symposium on Computer-Based Medical Systems (CBMS'06)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116867017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. S. Jadhav, S. Banerjee, P. Dutta, R. Paul, M. Pal, P. Banerjee, K. Chaudhuri, J. Chatterjee
This paper aims at quantitative analysis of histopathological features of precancerous lesion and condition using image processing technique. The algorithm involves median and low pass filtering, segmentation by adaptive region growing, optimal and local thresholding, morphological operations such as opening and closing of gray scale and binary images and some numerical methods. Differentiation on the basis of type and level of precancerous type or condition is carried out based on image marker, defined as a vector of cancer related features viz. length and curvature of radius of rete-ridges and papillae, population density of cells within epithelium, etc. Implementation of presented algorithms is done in MATLAB. The results support quantitative analysis of pathological condition in respect with progression towards malignancy. This analysis may help in developing automated analysis tool
{"title":"Quantitative Analysis of Histopathological Features of Precancerous Lesion and Condition Using Image Processing Technique","authors":"A. S. Jadhav, S. Banerjee, P. Dutta, R. Paul, M. Pal, P. Banerjee, K. Chaudhuri, J. Chatterjee","doi":"10.1109/CBMS.2006.137","DOIUrl":"https://doi.org/10.1109/CBMS.2006.137","url":null,"abstract":"This paper aims at quantitative analysis of histopathological features of precancerous lesion and condition using image processing technique. The algorithm involves median and low pass filtering, segmentation by adaptive region growing, optimal and local thresholding, morphological operations such as opening and closing of gray scale and binary images and some numerical methods. Differentiation on the basis of type and level of precancerous type or condition is carried out based on image marker, defined as a vector of cancer related features viz. length and curvature of radius of rete-ridges and papillae, population density of cells within epithelium, etc. Implementation of presented algorithms is done in MATLAB. The results support quantitative analysis of pathological condition in respect with progression towards malignancy. This analysis may help in developing automated analysis tool","PeriodicalId":208693,"journal":{"name":"19th IEEE Symposium on Computer-Based Medical Systems (CBMS'06)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121057493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The process of hypothesis-driven epidemiological research has three phases - the establishment and characterisation of a large, representative cohort from a geographically distributed population; the integration of the cohort data with other data sources to provide additional characterisation; the formulation of a hypothesis and generation of the corresponding predictions. Grid-computing technologies make possible secure, distributed collaboration, and the ability to share data sources, computational resources and storage resources across administrative boundaries. PsyGrid is an e-science project established to apply grid-computing technologies to each of the three phases, with the aim of eliminating the obstacles that hinder epidemiological research. We describe a system for distributed cohort characterisation, and the first application to the study of first episode psychosis
{"title":"PsyGrid: Applying e-Science to Epidemiology","authors":"J. Ainsworth, R. Harper, Ismael Juma, I. Buchan","doi":"10.1109/CBMS.2006.135","DOIUrl":"https://doi.org/10.1109/CBMS.2006.135","url":null,"abstract":"The process of hypothesis-driven epidemiological research has three phases - the establishment and characterisation of a large, representative cohort from a geographically distributed population; the integration of the cohort data with other data sources to provide additional characterisation; the formulation of a hypothesis and generation of the corresponding predictions. Grid-computing technologies make possible secure, distributed collaboration, and the ability to share data sources, computational resources and storage resources across administrative boundaries. PsyGrid is an e-science project established to apply grid-computing technologies to each of the three phases, with the aim of eliminating the obstacles that hinder epidemiological research. We describe a system for distributed cohort characterisation, and the first application to the study of first episode psychosis","PeriodicalId":208693,"journal":{"name":"19th IEEE Symposium on Computer-Based Medical Systems (CBMS'06)","volume":"217 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121108558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In order for structure prediction researchers to better understand the results of their algorithms and to enable life science researchers to interpret RNA structure easily, it is helpful to provide them with a flexible and powerful tool for RNA secondary structure visualization. jViz.Rna is a multi-platform visualization tool capable of displaying RNA secondary structures encoded in a variety of file formats. A single structure can be shown using the linear Feynman, circular Feynman, dot plot, and classical structure visualization models. The resulting drawings are dynamic and can easily be further modified by the user. Any of the drawings produced can be saved to disk enabling easy dissemination. The unique usage of a spring model for classical structure drawing allows for clear visualization of pseudoknots with minimal overlaps. The addition of a locality tool allows for the isolation of pseudoknotted regions or other regions of interest
{"title":"jViz.Rna - An Interactive Graphical Tool for Visualizing RNA Secondary Structure Including Pseudoknots","authors":"K. Wiese, E. Glen","doi":"10.1109/CBMS.2006.104","DOIUrl":"https://doi.org/10.1109/CBMS.2006.104","url":null,"abstract":"In order for structure prediction researchers to better understand the results of their algorithms and to enable life science researchers to interpret RNA structure easily, it is helpful to provide them with a flexible and powerful tool for RNA secondary structure visualization. jViz.Rna is a multi-platform visualization tool capable of displaying RNA secondary structures encoded in a variety of file formats. A single structure can be shown using the linear Feynman, circular Feynman, dot plot, and classical structure visualization models. The resulting drawings are dynamic and can easily be further modified by the user. Any of the drawings produced can be saved to disk enabling easy dissemination. The unique usage of a spring model for classical structure drawing allows for clear visualization of pseudoknots with minimal overlaps. The addition of a locality tool allows for the isolation of pseudoknotted regions or other regions of interest","PeriodicalId":208693,"journal":{"name":"19th IEEE Symposium on Computer-Based Medical Systems (CBMS'06)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121355464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brian S. Tani, Tiago Nobrega, T. R. D. Santos, A. V. Wangenheim
We present a visualization and manipulation framework for three-dimensional medical environments. The MVC architecture of the. framework allows the use of different API technologies such us OpenGL and DirectSD, different model representations, and controllers. This facilitates the implementation of medical applications offering resources commonly needed by such systems. Two case studies are shown as examples of such applications
{"title":"Generic Visualization and Manipulation Framework for Three-Dimensional Medical Environments","authors":"Brian S. Tani, Tiago Nobrega, T. R. D. Santos, A. V. Wangenheim","doi":"10.1109/CBMS.2006.91","DOIUrl":"https://doi.org/10.1109/CBMS.2006.91","url":null,"abstract":"We present a visualization and manipulation framework for three-dimensional medical environments. The MVC architecture of the. framework allows the use of different API technologies such us OpenGL and DirectSD, different model representations, and controllers. This facilitates the implementation of medical applications offering resources commonly needed by such systems. Two case studies are shown as examples of such applications","PeriodicalId":208693,"journal":{"name":"19th IEEE Symposium on Computer-Based Medical Systems (CBMS'06)","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115519717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Shankar, S. Martins, M. O'Connor, David B. Parrish, Amar K. Das
Clinical trials are formal patient studies that serve as the gold standard method for establishing the efficacy of medical treatments. There is an enormous requirement to specify the knowledge used at all stages of clinical trials, including planning, implementation, and analysis, so that they can be faithfully executed by a clinical research organization. We are building Epoch, a knowledge-based system, to help a large research consortium, the immune tolerance network (ITN), undertake trials to advance new therapeutics in immune-mediated disorders. We are currently targeting two application areas essential to the successful implementation of a trial: (1) tracking study participants as they advance through a study, and (2) tracking biological specimens as they are processed at laboratories. In this paper, we discuss our use of the Web ontology language (OWL) to create a suite of ontologies that conceptualize the clinical trial domain and show how they can inform our system. We show that our ontological framework provides a stable, consistent platform to define, maintain, and distribute the knowledge requirements used in clinical trial management
{"title":"Knowledge-Based System for Managing Complex Clinical Trials","authors":"R. Shankar, S. Martins, M. O'Connor, David B. Parrish, Amar K. Das","doi":"10.1109/CBMS.2006.107","DOIUrl":"https://doi.org/10.1109/CBMS.2006.107","url":null,"abstract":"Clinical trials are formal patient studies that serve as the gold standard method for establishing the efficacy of medical treatments. There is an enormous requirement to specify the knowledge used at all stages of clinical trials, including planning, implementation, and analysis, so that they can be faithfully executed by a clinical research organization. We are building Epoch, a knowledge-based system, to help a large research consortium, the immune tolerance network (ITN), undertake trials to advance new therapeutics in immune-mediated disorders. We are currently targeting two application areas essential to the successful implementation of a trial: (1) tracking study participants as they advance through a study, and (2) tracking biological specimens as they are processed at laboratories. In this paper, we discuss our use of the Web ontology language (OWL) to create a suite of ontologies that conceptualize the clinical trial domain and show how they can inform our system. We show that our ontological framework provides a stable, consistent platform to define, maintain, and distribute the knowledge requirements used in clinical trial management","PeriodicalId":208693,"journal":{"name":"19th IEEE Symposium on Computer-Based Medical Systems (CBMS'06)","volume":"435 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116011086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diabetes mellitus is one of the top five killer among both man and woman world wide. Type I diabetes is caused by the failure to produce sufficient insulin which leads to an uncontrolled increase in blood glucose. Prolong elevated glucose level of above 150-160mg/dl poses significant health risk with possible long lasting effect. Human assisted insulin injection through compartmental model schedules are basically open loop system. This paper attempts to close the loop by employing model reference adaptive control on a controller to adaptively control the glucose level of the patient via an infusion pump. Simulation results show the potential of using fuzzy type controllers for finer regulation and its practical applications
{"title":"Model Reference Adaptive Control on Glucose for the Treatment of Diabetes Mellitus","authors":"A. Wahab, Y. Kong, Hiok Chai Quek","doi":"10.1109/CBMS.2006.117","DOIUrl":"https://doi.org/10.1109/CBMS.2006.117","url":null,"abstract":"Diabetes mellitus is one of the top five killer among both man and woman world wide. Type I diabetes is caused by the failure to produce sufficient insulin which leads to an uncontrolled increase in blood glucose. Prolong elevated glucose level of above 150-160mg/dl poses significant health risk with possible long lasting effect. Human assisted insulin injection through compartmental model schedules are basically open loop system. This paper attempts to close the loop by employing model reference adaptive control on a controller to adaptively control the glucose level of the patient via an infusion pump. Simulation results show the potential of using fuzzy type controllers for finer regulation and its practical applications","PeriodicalId":208693,"journal":{"name":"19th IEEE Symposium on Computer-Based Medical Systems (CBMS'06)","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128486257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Brankin, P. Mccullagh, N. Black, William Patton, A. Muldrew
The application of image processing to the investigation of age-related macular degeneration (AMD) has focused on detecting focal drusen deposits in retinal images. This research investigates algorithmic approaches in order to detect choroidal neovascularisation (CNV) from retinal fluorescein angiograms in exudative AMD, the most severe form of the disease. A combination of the 'Sobel' edge detection algorithm combined with thresholding produced the best qualitative segmentation, as verified by a trained ophthalmic grader. This study confirms that image processing can be used to identify certain types of CNV in retinal images particularly those that are hyper fluorescent. Further work is necessary to quantify the total lesion and characterise the clinically significant sub-components: classic or occult leakage, blood or exudate
{"title":"The Optimisation of Thresholding Techniques for the Identification of Choroidal Neovascular Membranes in Exudative Age-Related Macular Degeneration","authors":"E. Brankin, P. Mccullagh, N. Black, William Patton, A. Muldrew","doi":"10.1109/CBMS.2006.157","DOIUrl":"https://doi.org/10.1109/CBMS.2006.157","url":null,"abstract":"The application of image processing to the investigation of age-related macular degeneration (AMD) has focused on detecting focal drusen deposits in retinal images. This research investigates algorithmic approaches in order to detect choroidal neovascularisation (CNV) from retinal fluorescein angiograms in exudative AMD, the most severe form of the disease. A combination of the 'Sobel' edge detection algorithm combined with thresholding produced the best qualitative segmentation, as verified by a trained ophthalmic grader. This study confirms that image processing can be used to identify certain types of CNV in retinal images particularly those that are hyper fluorescent. Further work is necessary to quantify the total lesion and characterise the clinically significant sub-components: classic or occult leakage, blood or exudate","PeriodicalId":208693,"journal":{"name":"19th IEEE Symposium on Computer-Based Medical Systems (CBMS'06)","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121301894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
During the last past years, cooperatives medical practices in healthcare networks have emerged and evolved drastically. Within these networks, healthcare professionals take care of patients, according to their degree of expertise, in contact with the others members for heaviest or simplest cases. An ubiquitous element in these medical documents is annotation. The issue of considering these annotations in computerized medical documents exchanged within healthcare networks is fundamental to the integrity and quality of future medical information systems. In this paper we highlight, based on the study of concrete medical information and their annotations, the fact that these documents belong to the peculiar category of "documents for action" and we also emphasize the potential of the HL7 CDA standard to represent and exchange these annotations in such networks
{"title":"On the Interest of Using HL7 CDA Release 2 for the Exchange of Annotated Medical Documents","authors":"M. Treins, Olivier Curé, G. Salzano","doi":"10.1109/CBMS.2006.123","DOIUrl":"https://doi.org/10.1109/CBMS.2006.123","url":null,"abstract":"During the last past years, cooperatives medical practices in healthcare networks have emerged and evolved drastically. Within these networks, healthcare professionals take care of patients, according to their degree of expertise, in contact with the others members for heaviest or simplest cases. An ubiquitous element in these medical documents is annotation. The issue of considering these annotations in computerized medical documents exchanged within healthcare networks is fundamental to the integrity and quality of future medical information systems. In this paper we highlight, based on the study of concrete medical information and their annotations, the fact that these documents belong to the peculiar category of \"documents for action\" and we also emphasize the potential of the HL7 CDA standard to represent and exchange these annotations in such networks","PeriodicalId":208693,"journal":{"name":"19th IEEE Symposium on Computer-Based Medical Systems (CBMS'06)","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2006-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124334616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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