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19th IEEE Symposium on Computer-Based Medical Systems (CBMS'06)最新文献

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Development of a Computer-Aided Tool for Evaluation and Training in 3D Spatial Cognitive Function 三维空间认知功能评估与训练计算机辅助工具的开发
Pub Date : 2006-06-22 DOI: 10.1109/CBMS.2006.75
Ching-Fen Jiang, De-Kai Chen, Yuan-Si Li, Jheng-Long Kuo
The proportion of senile people tends to increase in the global population. The cognitive impairment in the three dimensional (3D) space is usually associated with senile dementia. This paper presents a computer-aid tool developed to evaluate and train the cognitive ability in the 3D space by using the virtual reality technique. Once the norm is developed, this tool can assist the physiotherapist to evaluate the patients' 3D cognitive function in a more objective and efficient way. The viability of 3D cognitive training will be evaluated among the normal subjects prior to clinical trials
全球人口中老年人的比例有增加的趋势。三维空间的认知障碍通常与老年性痴呆有关。本文介绍了一种利用虚拟现实技术开发的评估和训练三维空间认知能力的计算机辅助工具。一旦制定了规范,该工具可以帮助物理治疗师更客观有效地评估患者的三维认知功能。在临床试验之前,将在正常受试者中评估3D认知训练的可行性
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引用次数: 7
Distance Functions Association for Content-Based Image Retrieval using Multiple Comparison Criteria 基于内容的多比较标准图像检索的距离函数关联
Pub Date : 2006-06-22 DOI: 10.1109/CBMS.2006.78
I. Pola, A. Traina, C. Traina
The comparison operators available in traditional database management systems (DBMS) are not adequate to handle complex data such as images, rather comparing them using similarity operators is the option of choice. Similarity operators need a way to measure the similarity between pairs of objects. Although there are many interesting works dealing with similarity queries and functions to measure similarity, they all rely on a single similarity function that must be applicable over the whole dataset. However, images from medical exams often require several ways to measure similarity, depending on many factors, such as the particular pathological condition being searched, or the existence of specific clinical condition revealed in the images compared. Therefore, the ability to handle several ways to compare images by similarity is important in medical software handling images. This work develop a technique to allow several similarity functions to be combined when indexing a large set of images, allowing queries to probe the dataset regarding distinct comparison criteria. This technique also allows a flexible way to pose queries supporting fast retrieval of the answers
传统数据库管理系统(DBMS)中可用的比较操作符不足以处理像图像这样的复杂数据,而使用相似操作符对它们进行比较是一种选择。相似算子需要一种度量对象对之间相似度的方法。尽管有许多有趣的工作处理相似性查询和度量相似性的函数,但它们都依赖于必须适用于整个数据集的单个相似性函数。然而,来自医学检查的图像通常需要几种方法来测量相似性,这取决于许多因素,例如正在搜索的特定病理状况,或者在比较的图像中显示的特定临床状况的存在。因此,在处理图像的医疗软件中,处理几种通过相似性比较图像的方法的能力是很重要的。这项工作开发了一种技术,允许在索引大量图像时组合几个相似函数,允许查询根据不同的比较标准探测数据集。该技术还允许以灵活的方式提出支持快速检索答案的查询
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引用次数: 1
Using DecisionTrees for Real-Time Ischemia Detection 利用决策树进行实时缺血检测
Pub Date : 2006-06-22 DOI: 10.1109/CBMS.2006.163
L. Dranca, A. Goñi, A. Illarramendi
In this paper we investigate if techniques based on decision trees are also useful to classify ischemia. In order to do that, we have based on a previous own algorithm that is able of detecting ST-segment episodes, can be executed in real time and is lightweight enough to be implemented on mobile devices such as PDAs. Three main steps are performed by that algorithm: 1) signal preprocessing that extracts important features from the ECG signal 2) detection of suspect ST segment events and 3) rejection of irrelevant ST segment events. We have found that techniques based on decision trees are interesting for the last step in order to obtain a set of rules that reject some of the suspect ST segment events detected in the second step. The freely available part of the LTST database has been used to develop the detector and the rest of the same database has been used for validation purposes. The sensitivity of the detector over all the records of the LTST database is 89.89% for episodes annotated according to C protocol and the positive predictivity is 70.03% for episodes annotated according to A protocol. Those results improve our previously obtained ones and we think that they are comparable to other results that appear in the literature. However, it has to be noticed that we have not found works that detect ischemia in real time and show validation results over the LTST database
在本文中,我们研究了基于决策树的技术是否对缺血分类也有用。为了做到这一点,我们基于之前自己的算法,能够检测st段剧集,可以实时执行,并且足够轻量,可以在pda等移动设备上实现。该算法执行了三个主要步骤:1)信号预处理,从心电信号中提取重要特征;2)检测可疑ST段事件;3)拒绝无关ST段事件。我们发现,基于决策树的技术对于最后一步很有趣,因为它可以获得一组规则,这些规则可以拒绝第二步中检测到的一些可疑的ST段事件。LTST数据库中免费提供的部分用于开发检测器,同一数据库的其余部分用于验证目的。对于按C协议注释的事件,检测器对LTST数据库所有记录的灵敏度为89.89%,对按A协议注释的事件的阳性预测率为70.03%。这些结果改善了我们之前得到的结果,我们认为它们与文献中出现的其他结果相当。然而,必须注意的是,我们还没有发现实时检测缺血并在LTST数据库上显示验证结果的作品
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引用次数: 9
A Scalable Multi-tier Architecture for the National Taiwan University Hospital Information System based on HL7 Standard 基于HL7标准的台大医院信息系统可扩展多层体系结构
Pub Date : 2006-06-22 DOI: 10.1109/CBMS.2006.27
Tzu-Hsiang Yang, Po-Hsun Cheng, C. H. Yang, F. Lai, C. L. Chen, Hsiu-Hui Lee, K. Hsu, Chi-Huang Chen, Ching-Ting Tan, Yeali S. Sun
This article describes the successful experiences of National Taiwan University Hospital (NTUH) in moving from IBM Mainframe to connected networking computer systems. We use multi-tier architecture and HL7 standard to implement our new outpatient hospital information system (HIS). The NTUH HIS is a complex environment with several operating systems, databases, and information systems. We adopt service-oriented architecture (SOA) to reduce the complex relations between systems and solve data consistency problems among databases. We also show that the distributed architecture can provide us stable and reasonable system performances. Our main contribution is proving that the distributed environment with HL7 standard and SOA can sustain in a highly demanding environment
本文介绍了台大医院从IBM大型机向联网计算机系统转型的成功经验。我们采用多层体系结构和HL7标准来实现我们的新型门诊医院信息系统。NTUH HIS是一个包含多个操作系统、数据库和信息系统的复杂环境。采用面向服务的体系结构(SOA)来减少系统间的复杂关系,解决数据库间的数据一致性问题。结果表明,分布式架构能够提供稳定合理的系统性能。我们的主要贡献是证明具有HL7标准和SOA的分布式环境可以在高要求的环境中维持
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引用次数: 36
Synergy of Symmetric Region Grow and Active Contour in Reconstruction of a 3D Rat 对称区域生长和活动轮廓在三维大鼠重建中的协同作用
Pub Date : 2006-06-22 DOI: 10.1109/CBMS.2006.153
Shu-Yen Wan, Chian-Hung Hou
The general goal of this work is modeling and reconstruction of a three-dimensional (3D) rat from a series of two-dimensional (2D) images captured from an inexpensive digital camera. We proposed a hybrid segmentation method that incorporates symmetric region grow (symRG) and active contour modeling (ACM) to robustly extract regions of interest (ROIs), such as organs, spines, and vessels. symRG is employed to enhance the segmentation performance while the edge information passed from the ACM can help prevent over-segmentation. We built a component-based software platform that includes the symRG and ACM components as well as the other image enhancement, post-segmentation processing, surface rendering components allowing the user to dynamically compose a streamlined 3D rat reconstruction procedure or script. The example dataset in this paper include 284 slices of 2D rat whole-body images. Separate scripts were used to model and visualize the body, heart, lung, stomach, and head. Few user-imposed parameters were required and the whole processing , from loading series of 2D images towards 3D rendition to demonstrate the results, is within two minutes
这项工作的总体目标是从廉价的数码相机拍摄的一系列二维(2D)图像中建模和重建三维(3D)老鼠。我们提出了一种结合对称区域生长(symRG)和主动轮廓建模(ACM)的混合分割方法,以鲁棒提取感兴趣区域(roi),如器官、脊柱和血管。symRG用于提高分割性能,而ACM传递的边缘信息有助于防止过度分割。我们构建了一个基于组件的软件平台,其中包括symRG和ACM组件以及其他图像增强,后分割处理,表面渲染组件,允许用户动态编写精简的3D鼠重建程序或脚本。本文的示例数据集包括284张2D大鼠全身图像切片。单独的脚本被用来模拟和可视化身体、心脏、肺、胃和头部。几乎不需要用户强加的参数,整个过程,从加载一系列2D图像到3D渲染演示结果,在两分钟内完成
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引用次数: 0
Discrimination of Liver Diseases from CT Images Based on Gabor Filters 基于Gabor滤波器的肝脏疾病CT图像识别
Pub Date : 2006-06-22 DOI: 10.1109/CBMS.2006.77
Chien-Cheng Lee, Sz-Han Chen, H. Tsai, P. Chung, Yu-Chun Chiang
In this paper, a liver disease diagnosis based on Gabor filters is proposed. Three kinds of liver diseases are identified: cyst, hepatoma and cavernous hemangioma. The diagnosis scheme includes two steps: features extraction and classification. The features derived from Gabor filters are obtained from the ROIs among the normal and abnormal CT images. In the classification step the SVM classifier is used to discriminate the different liver disease types. Finally the receiver operating characteristic curve is employed to evaluate the performance of the diagnosis system. The effectiveness of the proposed method is demonstrated through experimental results on CT images including 76 liver cysts, 30 hepatomas, and 40 cavernous hemangiomas. From the results, we can observe that the discrimination rate of cyst is higher than the other diseases, and the classification accuracy decreases slightly between cavernous hemangiomas and hepatomas. However, a normal region can be discriminated from all of these diseases entirely
本文提出了一种基于Gabor滤波器的肝病诊断方法。确定了三种肝脏疾病:囊肿、肝癌和海绵状血管瘤。诊断方案包括特征提取和分类两个步骤。从正常和异常CT图像的roi中获得Gabor滤波器的特征。在分类步骤中,使用支持向量机分类器来区分不同的肝病类型。最后利用接收机工作特性曲线对诊断系统的性能进行评价。通过76个肝囊肿、30个肝癌和40个海绵状血管瘤的CT图像实验结果证明了该方法的有效性。从结果可以看出,囊肿的辨别率高于其他疾病,海绵状血管瘤与肝癌的分类准确率略有下降。然而,一个正常的区域可以完全与所有这些疾病区分开来
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引用次数: 21
A Modified Generalized RBF Model with EM-based Learning Algorithm for Medical Applications 基于em学习算法的改进广义RBF模型在医学中的应用
Pub Date : 2006-06-22 DOI: 10.1109/CBMS.2006.17
Li Ma, Abdul Wahab, Hiok-Chai Quek
Radial basis function (RBF) has been widely used in different fields, due to its fast learning and interpretability of its solution. One problem of classical RBF is that it suffers from curse of dimensionality that the number of basis functions would explode with the increase of dimensions in the dataset. This explosion usually impairs the usefulness and interpretability of RBF, especially in medical applications, where the dimensions of dataset are high and the explanations of solutions are important. In this paper, we propose a generalized RBF (GRBF) model to reduce the number of basis functions and thus alleviate curse of dimensionality. An EM-based training algorithm is also introduced, which uses fewer parameters compared to some classical supervised learning methods. This would make the learning process simpler and more convenient in practice. Moreover, GRBF trained by the new algorithm has an apparent statistical meaning. Experimental results show potentials for real-life applications
径向基函数(RBF)具有快速学习和解的可解释性等优点,在各个领域得到了广泛的应用。经典RBF的一个问题是它存在维数诅咒的问题,即随着数据集中维数的增加,基函数的数量会激增。这种爆炸通常会削弱RBF的有用性和可解释性,特别是在数据集维度高且解决方案的解释很重要的医疗应用中。本文提出了一种广义RBF (GRBF)模型,以减少基函数的数量,从而减轻维数的困扰。本文还介绍了一种基于模型的训练算法,该算法与一些经典的监督学习方法相比,使用的参数更少。这将使学习过程更简单,在实践中更方便。此外,新算法训练的GRBF具有明显的统计意义。实验结果显示了实际应用的潜力
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引用次数: 1
Biomedical Ontology MeSH Improves Document Clustering Qualify on MEDLINE Articles: A Comparison Study 生物医学本体网格提高MEDLINE文章的文档聚类质量的比较研究
Pub Date : 2006-06-22 DOI: 10.1109/CBMS.2006.62
Illhoi Yoo, Xiaohua Hu
Document clustering has been used for better document retrieval, document browsing, and text mining. In this paper, we investigate if biomedical ontology MeSH improves the clustering quality for MEDLINE articles. For this investigation, we perform a comprehensive comparison study of various document clustering approaches such as hierarchical clustering methods (single-link, complete-link, and complete link), bisecting K-means, K-means, and suffix tree clustering (STC) in terms of efficiency, effectiveness, and scalability. According to our experiment results, biomedical ontology MeSH significantly enhances clustering quality on biomedical documents. In addition, our results show that decent document clustering approaches, such as bisecting K-means, K-means and STC, gains some benefit from MeSH ontology while hierarchical algorithms showing the poorest clustering quality do not reap the benefit of MeSH ontology
文档聚类已被用于更好的文档检索、文档浏览和文本挖掘。在本文中,我们研究生物医学本体MeSH是否提高MEDLINE文章的聚类质量。在这项研究中,我们对各种文档聚类方法进行了全面的比较研究,如层次聚类方法(单链接、完整链接和完整链接)、分割K-means、K-means和后缀树聚类(STC)的效率、有效性和可扩展性。实验结果表明,生物医学本体MeSH显著提高了生物医学文档的聚类质量。此外,我们的结果表明,体面的文档聚类方法,如分割K-means、K-means和STC,从MeSH本体中获得了一些好处,而表现出最差聚类质量的分层算法并没有从MeSH本体中获得好处
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引用次数: 23
A Monte Carlo-Based Fiber Tracking Algorithm using Diffusion Tensor MRI 一种基于蒙特卡罗的扩散张量MRI光纤跟踪算法
Pub Date : 2006-06-22 DOI: 10.1109/CBMS.2006.20
F. Prados, A. Bardera, M. Sbert, I. Boada, M. Feixas
Diffusion tensor magnetic resonance imaging, which measures directional information of water diffusion in the brain, has emerged as a powerful tool for human brain studies. In this paper, we introduce a new Monte Carlo-based fiber tracking approach to estimate brain connectivity. One of the main characteristics of this approach is that all parameters of the algorithm are automatically determined at each point using the entropy of the eigenvalues of the diffusion tensor. Experimental results show the good performance of the proposed approach
扩散张量磁共振成像技术是一种测量水在大脑中扩散方向信息的技术,已成为研究人类大脑的有力工具。在本文中,我们介绍了一种新的基于蒙特卡罗的光纤跟踪方法来估计大脑连接。这种方法的一个主要特点是,算法的所有参数都是在每个点上使用扩散张量的特征值的熵自动确定的。实验结果表明,该方法具有良好的性能
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引用次数: 2
Design of a Compact System Using a MEMS Accelerometer to Measure Body Posture and Ambulation 基于MEMS加速度计的人体姿态和移动测量系统设计
Pub Date : 2006-06-22 DOI: 10.1109/CBMS.2006.73
K. Bliley, D. J. Schwab, D. Holmes, P. H. Kane, J. Levine, E. Daniel, B. Gilbert
Interest in studying human posture, movement, and physical activity is growing due in part to the increasing prevalence of obesity. Accelerometers are commonly used in motion analysis systems to enable researchers to conduct studies outside of the traditional laboratory environment; however the available systems tend to be bulky and unsuitable for long-term studies. Therefore, a need exists for a physically robust, yet compact motion analysis system that can be easily worn for an extended time period without disrupting the person's range of motion. Here we describe our on-going efforts to develop a robust, compact system that can measure body posture and movement using a tri-axial accelerometer, and then store this data on a secure digital memory card. This device can be easily configured to collect accelerometer data for specific applications in human motion analysis. In the future, this device will be used to study physical activity in free-living individuals
人们对研究人体姿势、运动和身体活动的兴趣越来越大,部分原因是肥胖日益普遍。加速度计通常用于运动分析系统,使研究人员能够在传统的实验室环境之外进行研究;然而,现有的系统往往体积庞大,不适合长期研究。因此,需要一种物理上坚固,但紧凑的运动分析系统,可以很容易地穿戴很长一段时间,而不会破坏人的运动范围。在这里,我们描述了我们正在进行的努力,以开发一个强大的,紧凑的系统,可以测量身体的姿势和运动使用三轴加速度计,然后将这些数据存储在一个安全的数字存储卡。该设备可以很容易地配置为人体运动分析的特定应用收集加速度计数据。未来,该设备将用于研究自由生活个体的身体活动
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引用次数: 15
期刊
19th IEEE Symposium on Computer-Based Medical Systems (CBMS'06)
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