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A Case Report of Non-Reactive Psychosis in a COVID-19 Patient COVID-19患者无反应性精神病1例报告
Pub Date : 2021-06-30 DOI: 10.24321/2454.8642.202104
M. Debnath
Background: COVID-19 causes reactive psychiatric symptoms like anxiety, depression, insomnia etc besides significant inflammatory response. A number of COVID-19 patients are found to present with complex neuropsychiatric syndromes, including the first onset of psychosis, that seem to be directly related to brain damage in the context of COVID-19. Most cases of psychotic disorder in COVID-19 patients are being found in individuals with no personal or family history of mental illness. Case Description: A 33-year-old man presented with acute restlessness, agitation, wandering, vandalizing things, suspiciousness, hallucinatory behaviour, decreased sleep for 3 days duration. There was no past history or family history of any psychiatric illness. There was a history of mild grade fever 7 days before the onset of the psychotic symptoms. The patient was uncooperative, irritable, and had hallucinatory behaviour. Rapid Antigen Test (RAT) was positive. The patient responded to injectable antipsychotic haloperidol which was later changed to Tab Olanzepine 5 mg. The patient developed no COVID symptoms and no psychotic symptoms were seen further. Conclusion: There is a possibility of a psychosis break as a COVID-19 clinical presentation, suggesting potential participation of inflammatory and autoimmunologic phenomena triggered as a response to the coronavirus infection.
背景:COVID-19除了引起明显的炎症反应外,还会引起焦虑、抑郁、失眠等反应性精神症状。发现许多COVID-19患者出现复杂的神经精神综合征,包括首次发病的精神病,这似乎与COVID-19背景下的脑损伤直接相关。大多数COVID-19患者的精神障碍病例都是在没有个人或家族精神病史的个体中发现的。病例描述:一名33岁男性,表现为急性躁动,躁动,徘徊,破坏物品,多疑,幻觉行为,睡眠减少3天。没有任何精神疾病的病史或家族史。出现精神症状前7天有轻度发热史。病人不合作,易怒,有幻觉行为。快速抗原试验(RAT)阳性。患者对注射抗精神病药氟哌啶醇有反应,后来改为奥兰平5毫克。患者没有出现COVID症状,也没有进一步的精神症状。结论:COVID-19的临床表现有可能是精神病发作,提示可能参与了对冠状病毒感染的反应引发的炎症和自身免疫现象。
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引用次数: 0
Tension Band Wiring for Fracture Patella Outcome with 3 K Wire versus 2 K Wire 张力带钢丝治疗髌骨骨折的效果:3k钢丝vs 2k钢丝
Pub Date : 2021-06-30 DOI: 10.24321/2454.8642.202103
S. Deb
Introduction: Fractures of the patella constitute almost 1% of all skeletal injuries, resulting from either direct or indirect trauma. Many forms of internal fixation for patellar fractures have been described in the literature but perfect anatomical reduction during surgery has an excellent outcome irrespective of the method of fixation used. The conventional method of patellar tension band wiring is always done with the help of two parallel Kirschner wires. Here, in our study, we intended to see whether the use of 3 parallel Kirschner wires in comparison to conventional one results in a superior functional outcome. Methods: A prospective observational study was carried out in ANIIMS and GB Pant hospital Port Blair from November 2016 to November 2019 on 44 patients of patellar fracture operated by tension band wiring with 22 patients in 2 parallel Kirschner wires and 3 parallel Kirschner wires groups respectively. Results: 44 patients were followed up postoperatively for 1 year and assessed by Lysholm knee score for pain status and working status and other variables. The mean age of the participants was 40.27 years (41.86 in two Kirschner wire group and 38.68 in three Kirschner wire group) in our study. Lysholm knee score, pain status, or working status was not significant throughout the mean follow-up periods for both groups. Conclusions: We found no significant difference between patellar TBW in 3 Kirschner wire and 2 Kirschner wire groups. However small sample size limits our study.
导读:髌骨骨折几乎占所有骨骼损伤的1%,由直接或间接创伤引起。文献中描述了许多形式的髌骨骨折内固定,但无论采用何种固定方法,手术中完美的解剖复位都具有良好的效果。常规的髌骨张力带连接方法通常是在两根平行克氏针的帮助下完成的。在这里,在我们的研究中,我们想看看与传统的克氏针相比,使用3根平行克氏针是否能获得更好的功能结果。方法:对2016年11月至2019年11月在英国布莱尔港ANIIMS和GB Pant医院行张力带钢丝术的44例髌骨骨折患者进行前瞻性观察研究,其中22例患者分别分为2平行克氏针组和3平行克氏针组。结果:44例患者术后随访1年,采用Lysholm膝关节评分评估疼痛状态、工作状态等指标。研究对象的平均年龄为40.27岁(2次克氏针组41.86岁,3次克氏针组38.68岁)。在两组的平均随访期间,Lysholm膝关节评分、疼痛状态或工作状态均无显著差异。结论:3组克氏针与2组克氏针髌骨TBW无显著性差异。然而,样本量小限制了我们的研究。
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引用次数: 0
A Case Report on Mephentermine Induced Psychosis with Acute Liver & Kidney Injury 甲非明所致精神病伴急性肝肾损伤1例
Pub Date : 2021-06-30 DOI: 10.24321/2454.8642.202102
M. Debnath
Background: Mephentermine is a sympathomimetic agent derived from methamphetamine. It is a commonly used drug for the treatment of hypotension during anaesthesia. Its abuse has markedly increased especially in the young population due to its stimulant properties and ability to boost performance in competitive sports or bodybuilding. Very few cases of Mephentermine dependence with or without psychosis have been reported from India and worldwide. Case Description: A 24-year-old male presented with a sudden onset of behavioural abnormalities a few hours following the use of Mephentermine. He was very agitated and restless. On physical examination, tachycardia, elevated BP and bilaterally dilated pupils were found. His symptoms remitted within a few hours of using Injection Haloperidol 10 mg with Lorazepam 4 mg once. He was found to have grossly deranged liver and kidney function tests. There was no past and family history of any psychiatric illness. No past history of any physical illness. Conclusion: No previous report of mephentermine induced psychosis with acute kidney and liver injury has been reported in the literature. Cases such as this may be common among the general public. Long term follow-up is required to know the course and outcome in such unusual cases.
背景:甲苯丙胺是一种源自甲基苯丙胺的拟交感神经药物。它是一种常用的药物,用于治疗麻醉期间的低血压。它的滥用明显增加,特别是在年轻人中,因为它的兴奋剂特性和提高竞技运动或健身成绩的能力。在印度和世界范围内,很少有伴有或不伴有精神病的甲非明依赖病例报告。病例描述:一名24岁男性,在使用苯丙胺几小时后突然出现行为异常。他非常激动不安。体格检查发现心动过速,血压升高,双侧瞳孔扩大。注射氟哌啶醇10毫克,劳拉西泮4毫克,几小时后症状缓解。他被发现肝肾功能严重紊乱。没有任何精神疾病的病史和家族史。过去没有任何身体疾病史。结论:文献中未见甲非明所致精神病合并急性肾、肝损伤的报道。这样的情况在公众中可能很常见。需要长期随访,以了解这种不寻常病例的过程和结果。
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引用次数: 1
Giant Cell Reparative Granuloma Presented as Nasal Mass: A Rare Entity 巨细胞修复性肉芽肿表现为鼻肿块:一种罕见的实体
Pub Date : 2021-06-30 DOI: 10.24321/2454.8642.202101
Sampa Choudhury
Giant Cell Reparative Granuloma (GCRG) is an unusual non-neoplastic lesion which most commonly involves maxilla and mandible. We present a case of GCRG of the nasal cavity in a young female presented with the complaint of progressively nasal obstruction. Radiological findings are usually nonspecific in this entity, therefore a good clinical, radiological and pathological correlation is needed for final diagnosis and to differentiate it from other giant cell lesions. Surgical excision is the preferred treatment modality over simple curettage.
巨细胞修复性肉芽肿(GCRG)是一种罕见的非肿瘤性病变,最常累及上颌骨和下颌骨。我们提出一个病例的鼻腔GCRG在一个年轻的女性提出的投诉进行性鼻塞。该疾病的影像学表现通常是非特异性的,因此需要良好的临床、影像学和病理相关性才能最终诊断并与其他巨细胞病变区分开来。与单纯刮除相比,手术切除是首选的治疗方式。
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引用次数: 0
A Study on Post-Sterilisation Failure in a Tertiary Care Hospital 某三级医院绝育后失败的研究
Pub Date : 2019-10-11 DOI: 10.24321/2454.8642.201914
M. Saha
1Associate Professor, Department of Community Medicine, ANIMS, Port Blair. 2Professor, Department of Obstetrics and Gynaecology, ANIMS, Port Blair. DOI: https://doi.org/10.24321/2454.8642.201914 Background: Female sterilization or tubal ligation is the most accepted method of contraception in India. The most popular method used in female sterilization in India is the laparoscopic tubal occlusion. Sterilization failure may occur, though rates are as low as around 0.10.3%. Objectives: The objectives of the study states to assess the prevalence of ectopic pregnancy and to study the types of ectopic pregnancies. Materials and Methods: This prospective study was conducted between January 2011 to December 2018 in the Obstetrics unit at GB Pant Hospital, ANIMS, Port Blair. Records of cases of post sterilization failure were studied. The results were described in proportions. Results: 76% of the sterilizations were done during interval period. 56% of recurrence occurred after 2-5 years of surgery. 61 % of the pregnancies after sterilisation failure were ectopic pregnancies. Conclusion: The chances of post sterilization failures though minimal, must be explained to the patients and when to seek medical help, to diagnose at the earliest.
1 .布莱尔港阿尼姆斯社区医学系副教授。2 .布莱尔港阿尼姆斯妇产科学系教授。DOI: https://doi.org/10.24321/2454.8642.201914背景:女性绝育或输卵管结扎是印度最接受的避孕方法。在印度,女性绝育最常用的方法是腹腔镜输卵管闭塞术。灭菌失败也可能发生,但发生率低至0.10.3%左右。目的:本研究的目的是评估异位妊娠的患病率和研究异位妊娠的类型。材料和方法:本前瞻性研究于2011年1月至2018年12月在布莱尔港阿尼姆斯GB潘特医院产科进行。研究了灭菌后失败的病例记录。结果用比例来描述。结果:76%的绝育手术在间歇期完成。术后2-5年复发率为56%。绝育失败后妊娠61%为异位妊娠。结论:绝育后失败的可能性虽小,但应及时向患者说明并及时就医,尽早诊断。
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引用次数: 1
Study of Anatomical Types of Pterion for Pterional Surgical Approach 翼点手术入路中翼点解剖类型的研究
Pub Date : 2019-10-11 DOI: 10.24321/2454.8642.201916
Dharmendra Kumar
Sachin Patil, Dharmendra Kumar 1Assistant Professor, Department of Anatomy, ANIIMS, Port Blair, Andaman and Nicobar Islands, India. 2Associate Professor & Head, Department of Physical Medicine and Rehabilitation, ANIIMS, Port Blair, Andaman and Nicobar Islands, India. DOI: https://doi.org/10.24321/2454.8642.201916 Introduction: Pterion is useful anatomical landmark for neurosurgeons during operations on frontal lobe tumours, extradural haemorrhage, Roca’s speech area or pathologies of middle cerebral artery. Material and Methods: This study was conducted in the on 120 dry human skulls. On the both side of each skull, the morphology of pterion was examined based on Murphy’s classification. Results: On examining the sutural pattern and types of pterion we found that Sphenoparietal type of pterion was most common type while the least common type was the epipteric type of pterion. Percentage of types was Sphenoparietal type 73.75%, Fronto temporal type 9.08%, stellate type 20% and epipteric type 7.16%. Conclusion: Types of the pterion in normal skulls shows great degree of variations among individuals and different racial groups. Therefore, precise and scientific data ar e required when performing intracranial surgery.
Sachin Patil, Dharmendra Kumar 1印度安达曼和尼科巴群岛布莱尔港ANIIMS解剖学系助理教授。2印度安达曼和尼科巴群岛布莱尔港ANIIMS物理医学和康复系副教授兼主任。DOI: https://doi.org/10.24321/2454.8642.201916简介:翼突是神经外科医生在额叶肿瘤、硬膜外出血、罗卡言语区或大脑中动脉病变手术中有用的解剖学标志。材料和方法:本研究在120个干燥的人头骨中进行。在每个颅骨两侧,根据Murphy的分类检查翼部形态。结果:检查翼状胬肉的缝合方式和类型,发现翼状胬肉以蝶顶型最常见,以翼状胬肉的表端型最不常见。其中蝶顶型占73.75%,额颞型占9.08%,星状型占20%,会阴型占7.16%。结论:正常颅骨翅片的类型在个体和种族间存在较大差异。因此,在进行颅内手术时,需要精确、科学的数据。
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引用次数: 1
Superior Mesenteric Artery Syndrome: Need for an Awareness 肠系膜上动脉综合征:需要认识
Pub Date : 2019-10-11 DOI: 10.24321/2454.8642.201918
Sushanta Chakma
Sushanta Chakma, Somshankar Chowdhury, AK Mandal 1,2Department of Pathology, VMMC and Safdarjung Hospital, New Delhi, India. 3Director Professor & HOD, Pathology Department, Dr Baba Sahib Ambedkar Medical College and Hospital, New Delhi. DOI: https://doi.org/10.24321/2454.8642.201918 Superior Mesenteric Artery (SMA) syndrome is an upper gastrointestinal disorder caused by the compression of the third part of the duodenum between Aorta and Superior mesenteric artery. SMA syndrome is a rare pathology with an incidence that ranges between 0.013 and 0.3%. It’s a rare cause of duodenal obstruction which may be complete or partial but is a life-threatening disorder as it poses a diagnostic dilemma. A patient was admitted in the emergency with complaints of subacute intestinal obstruction along with peritonitis. He underwent exploratory laparotomy along with surgical resection of gangrenous segment. Histopathological examination showed gangrenous bowel, however, no specific cause could be identified. CT findings were reviewed for a possible compression/ obstruction aetiology. It revealed features suggestive of superior mesenteric artery syndrome.
Sushanta Chakma, Somshankar Chowdhury, AK Mandal, 1,2印度新德里VMMC和Safdarjung医院病理科。3,新德里Baba Sahib Ambedkar医学院和医院病理科主任,教授和主任。DOI: https://doi.org/10.24321/2454.8642.201918肠系膜上动脉(SMA)综合征是由主动脉和肠系膜上动脉之间的十二指肠第三部分受压引起的上消化道疾病。SMA综合征是一种罕见的病理,发病率在0.013%至0.3%之间。这是一种罕见的十二指肠梗阻,可能是完全或部分的,但它是一种危及生命的疾病,因为它造成了诊断困境。病人因亚急性肠梗阻并发腹膜炎而急诊入院。他接受了探查性剖腹手术并切除坏疽节段。组织病理学检查显示肠坏疽,但没有确定具体原因。我们回顾了CT表现,以确定可能的压迫/阻塞病因。它显示提示肠系膜上动脉综合征的特征。
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引用次数: 0
Caesarean Section: A Necessary Evil? 剖腹产:必要之恶?
Pub Date : 2019-10-11 DOI: 10.24321/2454.8642.201915
S. S. Singh
Abhishek Malakar, Shiv Shankar Singh, Shreya Barik, Dhanisha S Awaradi 1Assistant Professor, 3Senior Resident, 4Internee, Department of Obstetrics and Gynaecology, ANIIMS, Port Blair, India. 2Associate Professor, Department of General Medicine, ANIIMS, Port Blair, India. DOI: https://doi.org/10.24321/2454.8642.201915 Background: Caesarean Section (CS) has become more prevalent over the years due to various factors and is exceeding the specified limit laid down by the WHO. Caesarean section is associated with various maternal and neonatal morbidities. With the alarming rise in Caesarean Section rate, these complications invariably increase. We conducted this study to assess the maternal and neonatal morbidities associated with CS in a tertiary care hospital in Andaman and Nicobar Islands, India. Methods: This was a prospective observational study done over a period of one year from January 2018 to December 2018. Data was collected for all CS performed in this time period and was statistically analysed by MS Excel, frequency distribution tables and SPSS Software. Result: Over the study period of one year, there were total 2646 deliveries with caesarean rate of 38.51% and more than 75% of these were primary caesarean section. Almost three fourth (73.61%) were emergency CS. Intraoperative adhesions and extension of uterine incision were common intraoperative complications whereas PPH was the most common post-operative morbidity. Intra operative complications were more in cases of emergency CS. Conclusion: We found a high CS rate with a high percentage of primary caesarean section along with various complications. With advancement in better maternal and foetal monitoring in labour in a tertiary care centre, it is desirable to be able to provide a safer vaginal delivery to patients that promises a better obstetric future. The decision to perform a Caesarean delivery must be chosen carefully, balancing risks and benefits, and not liberally. This is only possible if standard guidelines and protocols of management are in place at national and institutional levels. Only then the overall primary CS rate and its complications can best be avoided.
Abhishek Malakar, Shiv Shankar Singh, Shreya Barik, Dhanisha S Awaradi 1印度布莱尔港ANIIMS妇产科助理教授,3高级住院医师,4实习生。2印度布莱尔港ANIIMS综合医学部副教授。DOI: https://doi.org/10.24321/2454.8642.201915背景:多年来,由于各种因素,剖腹产(CS)变得越来越普遍,并且超过了世界卫生组织规定的特定限制。剖宫产与各种孕产妇和新生儿发病率有关。随着剖宫产率的惊人上升,这些并发症也随之增加。我们进行了这项研究,以评估印度安达曼和尼科巴群岛一家三级保健医院中与CS相关的孕产妇和新生儿发病率。方法:这是一项前瞻性观察研究,为期一年,从2018年1月到2018年12月。收集这段时间内所有CS的数据,并通过MS Excel、频率分布表和SPSS软件进行统计分析。结果:在1年的研究期间,共分娩2646例,剖宫产率为38.51%,其中75%以上为初次剖宫产。近四分之三(73.61%)为紧急CS。术中最常见的并发症是术中粘连和子宫切口延长,而PPH是最常见的术后并发症。术中并发症以急诊CS多见。结论:原发性剖宫产率高,并发症多。随着在三级保健中心更好地监测产妇和胎儿分娩,人们希望能够为患者提供更安全的阴道分娩,从而保证更好的产科未来。剖腹产的决定必须谨慎选择,平衡风险和收益,而不是随意选择。只有在国家和机构一级制订了标准的管理准则和规程,才有可能做到这一点。只有这样,才能最好地避免总体原发性CS率及其并发症。
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引用次数: 1
Study of Craniometric Point as a Landmark in Performing Posterolateral Surgeries on Skull 颅测量点作为颅骨后外侧手术标志的研究
Pub Date : 2019-10-11 DOI: 10.24321/2454.8642.201917
Dharmendra Kumar
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引用次数: 0
A Study on Evaluation of Laqshay in Andaman 安达曼地区Laqshay评价研究
Pub Date : 2019-10-11 DOI: 10.24321/2454.8642.201913
M. Saha
1Associate Professor, Department of Community Medicine, ANIMS, Port Blair. 2Professor, Department of Obstetrics and Gynaecology, ANIMS, Port Blair. DOI: https://doi.org/10.24321/2454.8642.201913 Background: Respectful maternity care plays a major role in maintaining wellbeing of the mother and newborn, and ensures positive cognitive and emotional development of the babies later in life. Objectives: Aim and objective of the study states to evaluate the implementation of respectful maternity Care and to evaluate the implementation of new born care guidelines in laqshay. Materials and Methods: A cross sectional study was designed to meet the objectives on this study between January to April 2019 using a structured questionnaire. Result: 95% of study population were not allowed to walk or change position during labour. Around 56.7% reported that direct pushing was done. Only 22% of mothers were allowed to choose their position of comfort. None were allowed to have a birth companion and all mothers were ensured privacy during labour. Conclusion: Repeated counselling/ reinforcement to the staff members and surprise frequent visits by authorities concerned to the labour room will still improve the respectful maternal care.
1 .布莱尔港阿尼姆斯社区医学系副教授。2 .布莱尔港阿尼姆斯妇产科学系教授。DOI: https://doi.org/10.24321/2454.8642.201913背景:尊重产妇护理在维持母亲和新生儿的福祉方面发挥着重要作用,并确保婴儿在以后的生活中获得积极的认知和情感发展。目的:本研究的目的和目的是评估尊重产妇护理的实施情况,并评估新生儿护理指南在laqshay的实施情况。材料和方法:为实现本研究的目标,在2019年1月至4月期间设计了一项横断面研究,采用结构化问卷。结果:95%的研究对象在分娩过程中不允许走动或改变体位。约56.7%的患者报告直接推入。只有22%的母亲被允许选择舒适的姿势。任何人都不允许有产伴,所有母亲在分娩期间都享有隐私。结论:对工作人员的反复辅导/强化和有关部门对产房的突击访问仍能提高产妇的尊重护理水平。
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引用次数: 0
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Recent Advances in Pathology & Laboratory Medicine
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