The radionuclides 60Co and 54Mn are the main activation products produced in the operation of nuclear power facilities. Wastewater with these radionuclides must be treated to meet standards before being discharged. A variety of zeolite imidazole frameworks (ZIFs) materials were synthesized at room temperature, and the adsorption effect of ZIF-67 was found to be the best through adsorption experiments on Co(II) and Mn(II). The thermal stability test and structural characterization of ZIF-67 were carried out. At the same time, the influence of the initial pH value, adsorption time, and initial concentration of the solution on the adsorption of Co(II) and Mn(II) by ZIF-67 was investigated. The results show that: ZIF-67 has a microporous structure with a BET surface area of 1,035.72 m2/g. In addition, ZIF-67 has good thermal stability, under the condition of pH = 6, a temperature of 303 K and the initial concentration of 500 mg/L. The saturated adsorption capacity for Co(II) and Mn(II) reached 230.25 mg/g and 338.75 mg/g, respectively. ZIF-67 exhibits good selective adsorption performance for Co(II) and Mn (II) in high concentration interfering ion solutions and multi-ion solutions. The adsorption process of ZIF-67 was analyzed by kinetics, thermodynamics, isotherms, and adsorption diffusion models. The analysis of thermodynamic parameters shows that the adsorption process of ZIF-67 to Co(II) and Mn(II) is spontaneous and endothermic. The pseudo-second-order kinetic model, Langmuir isotherm model, and Boyd model are more in line with the adsorption process of Co(II) and Mn(II) by ZIF-67. It shows that the active sites on the surface of ZIF-67 are evenly distributed, and the adsorption process is single-molecule chemical layer adsorption. In addition, the liquid film diffusion dominates the adsorption rate during the adsorption process of Co(II) and Mn(II) by ZIF-67.
{"title":"Study on the adsorption performance of zeolite imidazole frameworks materials for Co(II) and Mn(II) in solution","authors":"Ping Bao, Yipeng Zhou, Xiaowei Wang, Jinfeng Men, Chengqiang Liang, Hao Ding","doi":"10.1515/ract-2024-0274","DOIUrl":"https://doi.org/10.1515/ract-2024-0274","url":null,"abstract":"The radionuclides <jats:sup>60</jats:sup>Co and <jats:sup>54</jats:sup>Mn are the main activation products produced in the operation of nuclear power facilities. Wastewater with these radionuclides must be treated to meet standards before being discharged. A variety of zeolite imidazole frameworks (ZIFs) materials were synthesized at room temperature, and the adsorption effect of ZIF-67 was found to be the best through adsorption experiments on Co(II) and Mn(II). The thermal stability test and structural characterization of ZIF-67 were carried out. At the same time, the influence of the initial pH value, adsorption time, and initial concentration of the solution on the adsorption of Co(II) and Mn(II) by ZIF-67 was investigated. The results show that: ZIF-67 has a microporous structure with a BET surface area of 1,035.72 m<jats:sup>2</jats:sup>/g. In addition, ZIF-67 has good thermal stability, under the condition of pH = 6, a temperature of 303 K and the initial concentration of 500 mg/L. The saturated adsorption capacity for Co(II) and Mn(II) reached 230.25 mg/g and 338.75 mg/g, respectively. ZIF-67 exhibits good selective adsorption performance for Co(II) and Mn (II) in high concentration interfering ion solutions and multi-ion solutions. The adsorption process of ZIF-67 was analyzed by kinetics, thermodynamics, isotherms, and adsorption diffusion models. The analysis of thermodynamic parameters shows that the adsorption process of ZIF-67 to Co(II) and Mn(II) is spontaneous and endothermic. The pseudo-second-order kinetic model, Langmuir isotherm model, and Boyd model are more in line with the adsorption process of Co(II) and Mn(II) by ZIF-67. It shows that the active sites on the surface of ZIF-67 are evenly distributed, and the adsorption process is single-molecule chemical layer adsorption. In addition, the liquid film diffusion dominates the adsorption rate during the adsorption process of Co(II) and Mn(II) by ZIF-67.","PeriodicalId":21167,"journal":{"name":"Radiochimica Acta","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141785268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The present study investigates gross alpha (GA) radioactivity levels in hazelnut kernels purchased from markets in Türkiye. 10 different hazelnut samples were crushed and made ready for counting. The alpha counts were obtained via ELSEC 7286 low level alpha counter with ZnS scintillator and EMI 6097B photomultiplier tube. The samples were placed in front of the detector to acquire the counts. All samples were counted isochronously. In addition to the GA activity measurement, total annual effective dose (AED) value for different age groups owing to ingestion was calculated for each sample. It was observed that the GA radioactivity levels in the samples were quite low, and total AED values were considerably lower than the WHO worldwide average AED value (290 μSv/year).
{"title":"Measurement of gross alpha radioactivity levels and estimation of annual effective dose in hazelnut kernels","authors":"Gözde Tektaş, Buket Canbaz Öztürk","doi":"10.1515/ract-2023-0224","DOIUrl":"https://doi.org/10.1515/ract-2023-0224","url":null,"abstract":"The present study investigates gross alpha (GA) radioactivity levels in hazelnut kernels purchased from markets in Türkiye. 10 different hazelnut samples were crushed and made ready for counting. The alpha counts were obtained via ELSEC 7286 low level alpha counter with ZnS scintillator and EMI 6097B photomultiplier tube. The samples were placed in front of the detector to acquire the counts. All samples were counted isochronously. In addition to the GA activity measurement, total annual effective dose (AED) value for different age groups owing to ingestion was calculated for each sample. It was observed that the GA radioactivity levels in the samples were quite low, and total AED values were considerably lower than the WHO worldwide average AED value (290 μSv/year).","PeriodicalId":21167,"journal":{"name":"Radiochimica Acta","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141785478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Haladhara Naik, Ram Janam Singh, Srikant Pandurang Dange, Wooyoung Jang
Independent isomeric yield ratios (IR) of 128,130,132Sb, 131,133Te, 132,134I, 135Xe and 138Cs in the epi-cadmium neutron-induced fission of 245Cm have been measured for the first time by using an off-line gamma-ray spectrometric technique. The average energy of the epi-cadmium neutron spectrum (<En>) is 1.9 MeV. From the IR values, root mean square fragment angular momenta (JRMS) were deduced by using the spin dependent statistical model analysis. The IR and JRMS values of the fission products from the present work were compared with the literature data in the thermal neutron-induced fission of 245Cm to examine the role of excitation energy. Effect of nuclear structure on JRMS value was also examined.
{"title":"Independent isomeric yield ratios of fission products in the epi-cadmium neutron-induced fission of 245Cm","authors":"Haladhara Naik, Ram Janam Singh, Srikant Pandurang Dange, Wooyoung Jang","doi":"10.1515/ract-2024-0287","DOIUrl":"https://doi.org/10.1515/ract-2024-0287","url":null,"abstract":"Independent isomeric yield ratios (IR) of <jats:sup>128,130,132</jats:sup>Sb, <jats:sup>131,133</jats:sup>Te, <jats:sup>132,134</jats:sup>I, <jats:sup>135</jats:sup>Xe and <jats:sup>138</jats:sup>Cs in the epi-cadmium neutron-induced fission of <jats:sup>245</jats:sup>Cm have been measured for the first time by using an off-line gamma-ray spectrometric technique. The average energy of the epi-cadmium neutron spectrum (<<jats:italic>E</jats:italic> <jats:sub> <jats:italic>n</jats:italic> </jats:sub>>) is 1.9 MeV. From the IR values, root mean square fragment angular momenta (<jats:italic>J</jats:italic> <jats:sub>RMS</jats:sub>) were deduced by using the spin dependent statistical model analysis. The IR and J<jats:sub>RMS</jats:sub> values of the fission products from the present work were compared with the literature data in the thermal neutron-induced fission of <jats:sup>245</jats:sup>Cm to examine the role of excitation energy. Effect of nuclear structure on <jats:italic>J</jats:italic> <jats:sub>RMS</jats:sub> value was also examined.","PeriodicalId":21167,"journal":{"name":"Radiochimica Acta","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141743834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The residence time distribution (RTD) is very reliable, providing valuable information about the performance of process equipment such as reactors and columns. The aim of this work is to study the effect of agitation in the hydrodynamic column of flow-rig. In this case, residence time distribution (RTD) is determined using the radiotracer approach. The radiotracer is the Technetium Tc-99m with half decay 6 h. It also emits gamma rays with an energy of 0.140 MeV. 2 mL of approximately 9 mCi activity Tc-99m was injected inside the column. The results show that in the conditions studied the column presents the anomaly, dead volume. The Intensity function A(t) confirms this result. Agitation has a beneficial effect in the reduction of dead volume. To revise the conception of the column or study other parameters like the variation flow rate can reduce or eliminate the dead volume. The RTD model indicated the column behaved as a Plug flow reactor (PFR) with mixing cells in serie (J = 4) model and the RTD experiment verified the model well.
停留时间分布（RTD）非常可靠，可为反应器和塔等工艺设备的性能提供有价值的信息。这项工作的目的是研究流动钻机流体动力柱中搅拌的影响。在这种情况下，采用放射性示踪剂方法确定停留时间分布（RTD）。放射性示踪剂是半衰期为 6 h 的锝 Tc-99m，它还能发射能量为 0.140 MeV 的伽马射线。2 mL 约 9 mCi 活性的 Tc-99m 被注入色谱柱内。结果表明，在所研究的条件下，色谱柱出现了异常，即死体积。强度函数 A(t) 证实了这一结果。搅拌对减少死体积有好处。修改色谱柱的设计或研究其他参数（如变化流速）可以减少或消除死体积。热电阻模型表明，色谱柱表现为带有串联（J = 4）混合单元的塞流反应器（PFR）模型，热电阻实验很好地验证了该模型。
{"title":"Hydrodynamic study of a flow-rig column by means of a radiotracer technique modelling with DTS-Pro 4","authors":"Louisa Bounemia, Chaouki Benazzouz, Mouhamed Belamri","doi":"10.1515/ract-2023-0227","DOIUrl":"https://doi.org/10.1515/ract-2023-0227","url":null,"abstract":"The residence time distribution (RTD) is very reliable, providing valuable information about the performance of process equipment such as reactors and columns. The aim of this work is to study the effect of agitation in the hydrodynamic column of flow-rig. In this case, residence time distribution (RTD) is determined using the radiotracer approach. The radiotracer is the Technetium Tc-99m with half decay 6 h. It also emits gamma rays with an energy of 0.140 MeV. 2 mL of approximately 9 mCi activity Tc-99m was injected inside the column. The results show that in the conditions studied the column presents the anomaly, dead volume. The Intensity function <jats:italic>A</jats:italic>(<jats:italic>t</jats:italic>) confirms this result. Agitation has a beneficial effect in the reduction of dead volume. To revise the conception of the column or study other parameters like the variation flow rate can reduce or eliminate the dead volume. The RTD model indicated the column behaved as a Plug flow reactor (PFR) with mixing cells in serie (<jats:italic>J</jats:italic> = 4) model and the RTD experiment verified the model well.","PeriodicalId":21167,"journal":{"name":"Radiochimica Acta","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141613022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A multiscale model describing the kinetics of the processes taking place during the radiolysis of uranium hexafluoride (UF6) has been developed using fundamental physical and chemical principles. The model incorporates both the radiolysis and thermal terms. The processes of the radiolysis products release from the gas phase to the solid and vice versa are taken into account. The predictions of the model are verified against the available experimental data.
{"title":"Physicochemical model of uranium hexafluoride (UF6) radiolysis under action of alpha particles","authors":"Artem A. Danshin, Alexey A. Kovalishin","doi":"10.1515/ract-2023-0263","DOIUrl":"https://doi.org/10.1515/ract-2023-0263","url":null,"abstract":"A multiscale model describing the kinetics of the processes taking place during the radiolysis of uranium hexafluoride (UF<jats:sub>6</jats:sub>) has been developed using fundamental physical and chemical principles. The model incorporates both the radiolysis and thermal terms. The processes of the radiolysis products release from the gas phase to the solid and vice versa are taken into account. The predictions of the model are verified against the available experimental data.","PeriodicalId":21167,"journal":{"name":"Radiochimica Acta","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141569031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sabriye Yusan, Burak Mumcu, Eduardo A. López-Maldonado, Rachid EL Kaim Billah, Lahoucine Bahsis
In this study, the composite materials based on the incorporation of diatomite of graphene oxide (GO)/reduced graphene oxide (rGO/diatomite) were developed and characterized by different techniques (SEM, XRD, FTIR and BET). Developed composites were used for the first time in the removal of uranium ions from aqueous solutions. In adsorption studies, parameters affecting the adsorption efficiency such as solution pH, temperature, contact time and initial U(VI) concentration were investigated using full factorial experimental design (FFED). ANOVA (analysis of variance) analysis within the 95 % confidence interval of the model applied to control the compatibility of the model and the experimental findings was examined. Langmuir, Freundlich and Temkin isotherms were used to determine the adsorption model and related parameters were calculated. In addition, adsorption thermodynamic parameters such as enthalpy, Gibbs free energy change and entropy were calculated. The uranium removal behaviour on GO/diatomite and rGO/diatomite was better characterized by the pseudo-second order and Langmuir models, indicating that uranium ions were chemically adsorbed onto composite materials. Additionally, it was observed that higher temperatures promoted the uranium removal on GO/diatomite and rGO/diatomite, suggesting that the removal process was a spontaneous endothermic and exothermic reaction, respectively. In addition, the adsorption of U(VI) with GO/diatomite and rGO/diatomite was investigated using density functional theory (DFT) study. Configuration and adsorption energy were determined. The GO/diatomite composite materials can be a promising candidate as an adsorbent for the removal of uranium from aqueous solutions.
{"title":"Fabrication and characterization of graphene oxide and reduced graphene oxide decorated diatomite composite materials and their adsorption performance for uranium ions","authors":"Sabriye Yusan, Burak Mumcu, Eduardo A. López-Maldonado, Rachid EL Kaim Billah, Lahoucine Bahsis","doi":"10.1515/ract-2024-0292","DOIUrl":"https://doi.org/10.1515/ract-2024-0292","url":null,"abstract":"In this study, the composite materials based on the incorporation of diatomite of graphene oxide (GO)/reduced graphene oxide (rGO/diatomite) were developed and characterized by different techniques (SEM, XRD, FTIR and BET). Developed composites were used for the first time in the removal of uranium ions from aqueous solutions. In adsorption studies, parameters affecting the adsorption efficiency such as solution pH, temperature, contact time and initial U(VI) concentration were investigated using full factorial experimental design (FFED). ANOVA (analysis of variance) analysis within the 95 % confidence interval of the model applied to control the compatibility of the model and the experimental findings was examined. Langmuir, Freundlich and Temkin isotherms were used to determine the adsorption model and related parameters were calculated. In addition, adsorption thermodynamic parameters such as enthalpy, Gibbs free energy change and entropy were calculated. The uranium removal behaviour on GO/diatomite and rGO/diatomite was better characterized by the pseudo-second order and Langmuir models, indicating that uranium ions were chemically adsorbed onto composite materials. Additionally, it was observed that higher temperatures promoted the uranium removal on GO/diatomite and rGO/diatomite, suggesting that the removal process was a spontaneous endothermic and exothermic reaction, respectively. In addition, the adsorption of U(VI) with GO/diatomite and rGO/diatomite was investigated using density functional theory (DFT) study. Configuration and adsorption energy were determined. The GO/diatomite composite materials can be a promising candidate as an adsorbent for the removal of uranium from aqueous solutions.","PeriodicalId":21167,"journal":{"name":"Radiochimica Acta","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141569033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Qing Zhou, Yanjun Du, Zihao Feng, Qi Ren, Yang Wang, Xiaoyong Chen, Yang Li, Yun Wang
This work synthesized MnO2 modified winter melon-derived biochar (MnO2@WBC) using potassium permanganate oxidation/hydrothermal method for uranium(VI) removal. The factors influencing uranium(VI) adsorption by MnO2@WBC, including pH, adsorbent dosage, time, temperature, and initial U(VI) concentration were explored. The material’s performance was characterized, and the underlying mechanism of U(VI) removal was analyzed using various techniques. The characterization results indicated that the MnO2@WBC exhibited excellent dispersibility, suggesting that MnO2 effectively prevented WBC aggregation and enhanced the reactive surface area, and providing more active sites that can effectively promote the complexation and adsorption of U(VI). The process suggested a dominant role for chemical adsorption. The Freundlich isotherm model demonstrated a high degree of alignment with the observed adsorption behavior, indicating a predominantly multilayer adsorption process. Thermodynamic studies indicated that adsorption was a spontaneous endothermic process. The XPS analysis demonstrated that the adsorption process was primarily due to the formation of stable complexes with C–O, Mn–O–H and C=O. The results demonstrated that MnO2@WBC effectively removed U(VI), achieving a maximum adsorption capacity of 240.86 mg g−1 at a pH of 5.0. These findings provided a theoretical basis for the treatment of wastewater contaminated with U(VI).
{"title":"Preparation of MnO2 modified winter melon-derived biochar for enhanced adsorption of U(VI) from aqueous solution","authors":"Qing Zhou, Yanjun Du, Zihao Feng, Qi Ren, Yang Wang, Xiaoyong Chen, Yang Li, Yun Wang","doi":"10.1515/ract-2024-0301","DOIUrl":"https://doi.org/10.1515/ract-2024-0301","url":null,"abstract":"This work synthesized MnO<jats:sub>2</jats:sub> modified winter melon-derived biochar (MnO<jats:sub>2</jats:sub>@WBC) using potassium permanganate oxidation/hydrothermal method for uranium(VI) removal. The factors influencing uranium(VI) adsorption by MnO<jats:sub>2</jats:sub>@WBC, including pH, adsorbent dosage, time, temperature, and initial U(VI) concentration were explored. The material’s performance was characterized, and the underlying mechanism of U(VI) removal was analyzed using various techniques. The characterization results indicated that the MnO<jats:sub>2</jats:sub>@WBC exhibited excellent dispersibility, suggesting that MnO<jats:sub>2</jats:sub> effectively prevented WBC aggregation and enhanced the reactive surface area, and providing more active sites that can effectively promote the complexation and adsorption of U(VI). The process suggested a dominant role for chemical adsorption. The Freundlich isotherm model demonstrated a high degree of alignment with the observed adsorption behavior, indicating a predominantly multilayer adsorption process. Thermodynamic studies indicated that adsorption was a spontaneous endothermic process. The XPS analysis demonstrated that the adsorption process was primarily due to the formation of stable complexes with C–O, Mn–O–H and C=O. The results demonstrated that MnO<jats:sub>2</jats:sub>@WBC effectively removed U(VI), achieving a maximum adsorption capacity of 240.86 mg g<jats:sup>−1</jats:sup> at a pH of 5.0. These findings provided a theoretical basis for the treatment of wastewater contaminated with U(VI).","PeriodicalId":21167,"journal":{"name":"Radiochimica Acta","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141569032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohamed A. Gizawy, Hesham A. Shamsel-Din, Mohsen M. T. El-Tahawy, Ayman A. Ibrahim
Recently, tumor-targeted radionuclide therapy has gained much recognition for the treatment of metastasized cancer. There is a growing interest in using the theranostic radionuclide 47Sc, owing to its excellent chemical and nuclear properties. However, the available chelating agents require a relatively high temperature for their radiolabeling, which could denature biomolecules. The aim of the present study is to synthesize a dipeptide agent that forms a thermodynamically more stable complex with 47Sc at room temperature. A novel α-amino acid ester derivative attached to pyrazine and tetrazole heterocyclic rings has been prepared by the azide coupling method. Different spectroscopic methods (FT-IR, 1H NMR, and mass spectra) were used for characterization of the target compound. The newly synthesized dipeptide was radiolabeled with 47Sc, and a high radiochemical yield of 98.5 ± 1.5 % and in vitro serum stability up to 72 h were attained at room temperature within 20 min. The quantum chemical calculations at B3PW91/6-31G(d) level were employed to establish the molecular structure of the dipeptide and its complexation with 47Sc. The selectivity of 47Sc-dipeptide toward localization in tumor cells was performed by molecular docking on different receptors in addition to in vivo biodistribution on solid tumor-bearing mice. A high T/NT ratio of 8.16 was obtained after 4 h p.i, suggesting that this complex could be used as a potential cancer theranostic agent.
{"title":"Synthesis, in silico and biodistribution studies of a novel 47Sc-radiolabeled α-amino acid ester derivative attached to pyrazine and tetrazole rings for tumor targeted radiotherapy","authors":"Mohamed A. Gizawy, Hesham A. Shamsel-Din, Mohsen M. T. El-Tahawy, Ayman A. Ibrahim","doi":"10.1515/ract-2023-0175","DOIUrl":"https://doi.org/10.1515/ract-2023-0175","url":null,"abstract":"Recently, tumor-targeted radionuclide therapy has gained much recognition for the treatment of metastasized cancer. There is a growing interest in using the theranostic radionuclide <jats:sup>47</jats:sup>Sc, owing to its excellent chemical and nuclear properties. However, the available chelating agents require a relatively high temperature for their radiolabeling, which could denature biomolecules. The aim of the present study is to synthesize a dipeptide agent that forms a thermodynamically more stable complex with <jats:sup>47</jats:sup>Sc at room temperature. A novel <jats:italic>α</jats:italic>-amino acid ester derivative attached to pyrazine and tetrazole heterocyclic rings has been prepared by the azide coupling method. Different spectroscopic methods (FT-IR, <jats:sup>1</jats:sup>H NMR, and mass spectra) were used for characterization of the target compound. The newly synthesized dipeptide was radiolabeled with <jats:sup>47</jats:sup>Sc, and a high radiochemical yield of 98.5 ± 1.5 % and <jats:italic>in vitro</jats:italic> serum stability up to 72 h were attained at room temperature within 20 min. The quantum chemical calculations at B3PW91/6-31G(d) level were employed to establish the molecular structure of the dipeptide and its complexation with <jats:sup>47</jats:sup>Sc. The selectivity of <jats:sup>47</jats:sup>Sc-dipeptide toward localization in tumor cells was performed by molecular docking on different receptors in addition to <jats:italic>in vivo</jats:italic> biodistribution on solid tumor-bearing mice. A high T/NT ratio of 8.16 was obtained after 4 h p.i, suggesting that this complex could be used as a potential cancer theranostic agent.","PeriodicalId":21167,"journal":{"name":"Radiochimica Acta","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141552516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maha Ali Youssef, Gehan Abdel Rahman Sadek Dakroury, Hisham Soliman Hassan
In this study, three starch hydrogels composite prepared using different ratios of starch, citric acid, acrylamide, and MgO nanoparticles (referred to as St1-g-(CA-AM), St2-g-(CA-AM), and St3-g-(CA-AM) MgO). These materials were assessed using FT-IR, SEM, and EDX. The adsorption of 134Cs(I) and 60Co (II) onto these materials studied using radiometric analysis. The investigation focused on how temperature, contact duration, initial metal ion concentration, and pH of the solution affected the sorption efficiency. It is found that a pH value of 7 optimized the adsorption reaction, reaching equilibrium after 40 minutes. The kinetics of the adsorption followed a pseudo-second order model. The Langmuir model adequately explained the sorption mechanism, supported by the analysis of isotherm models. The monolayer adsorption capacities for 60Co (II) and 134Cs (I) were 113.38 and 100.2 mg g−1, respectively. The thermodynamic study indicated that the sorption process is both endothermic and spontaneous.
{"title":"Separation studies of 60Co (II) and 134Cs (I) radionuclides from aqueous solution using starch-grafted citric acid-acrylamide/magnesia hydrogel","authors":"Maha Ali Youssef, Gehan Abdel Rahman Sadek Dakroury, Hisham Soliman Hassan","doi":"10.1515/ract-2024-0295","DOIUrl":"https://doi.org/10.1515/ract-2024-0295","url":null,"abstract":"In this study, three starch hydrogels composite prepared using different ratios of starch, citric acid, acrylamide, and MgO nanoparticles (referred to as St<jats:sub>1</jats:sub>-g-(CA-AM), St<jats:sub>2</jats:sub>-g-(CA-AM), and St<jats:sub>3</jats:sub>-g-(CA-AM) MgO). These materials were assessed using FT-IR, SEM, and EDX. The adsorption of <jats:sup>134</jats:sup>Cs(I) and <jats:sup>60</jats:sup>Co (II) onto these materials studied using radiometric analysis. The investigation focused on how temperature, contact duration, initial metal ion concentration, and pH of the solution affected the sorption efficiency. It is found that a pH value of 7 optimized the adsorption reaction, reaching equilibrium after 40 minutes. The kinetics of the adsorption followed a pseudo-second order model. The Langmuir model adequately explained the sorption mechanism, supported by the analysis of isotherm models. The monolayer adsorption capacities for <jats:sup>60</jats:sup>Co (II) and <jats:sup>134</jats:sup>Cs (I) were 113.38 and 100.2 mg g<jats:sup>−1</jats:sup>, respectively. The thermodynamic study indicated that the sorption process is both endothermic and spontaneous.","PeriodicalId":21167,"journal":{"name":"Radiochimica Acta","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141503020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jacy K. Conrad, Michael E. Woods, Gregory P. Horne
Innovative solutions are needed to reduce the amount of high-level waste generated by used nuclear fuel recycling strategies to support the widespread adoption of sustainable nuclear fission energy technologies. To this end, a new sulfur chloride-based process has been developed to recycle zirconium alloy-based materials, which make up a significant fraction of high-level radioactive waste. To support the continued development of this process, we present new data on the potential reaction pathways over time of the products arising from the gamma and electron beam radiolysis of neat thionyl chloride (SOCl2). Interrogation of the gamma irradiated liquid by Raman spectroscopy provided more conclusive identification of the SOCl2 degradation products, specifically sulfur dichloride (SCl2), molecular chlorine (Cl2), sulfur dioxide (SO2), and sulfuryl chloride (SO2Cl2). In comparison, the high dose rate (∼107 Gy s−1) electron beam irradiations formed significantly more degradation products. For both cobalt-60 gamma and electron beam irradiations, the observed degradation products were found to evolve as a function of time post-irradiation via the same reaction pathways, with indication of a solvent regeneration mechanism. These findings are fortuitous for process development, as such a mechanism would be beneficial for process longevity and cost effectiveness.
{"title":"Identification and time evolution of thionyl chloride (SOCl2) radiolysis products","authors":"Jacy K. Conrad, Michael E. Woods, Gregory P. Horne","doi":"10.1515/ract-2024-0288","DOIUrl":"https://doi.org/10.1515/ract-2024-0288","url":null,"abstract":"Innovative solutions are needed to reduce the amount of high-level waste generated by used nuclear fuel recycling strategies to support the widespread adoption of sustainable nuclear fission energy technologies. To this end, a new sulfur chloride-based process has been developed to recycle zirconium alloy-based materials, which make up a significant fraction of high-level radioactive waste. To support the continued development of this process, we present new data on the potential reaction pathways over time of the products arising from the gamma and electron beam radiolysis of neat thionyl chloride (SOCl<jats:sub>2</jats:sub>). Interrogation of the gamma irradiated liquid by Raman spectroscopy provided more conclusive identification of the SOCl<jats:sub>2</jats:sub> degradation products, specifically sulfur dichloride (SCl<jats:sub>2</jats:sub>), molecular chlorine (Cl<jats:sub>2</jats:sub>), sulfur dioxide (SO<jats:sub>2</jats:sub>), and sulfuryl chloride (SO<jats:sub>2</jats:sub>Cl<jats:sub>2</jats:sub>). In comparison, the high dose rate (∼10<jats:sup>7</jats:sup> Gy s<jats:sup>−1</jats:sup>) electron beam irradiations formed significantly more degradation products. For both cobalt-60 gamma and electron beam irradiations, the observed degradation products were found to evolve as a function of time post-irradiation via the same reaction pathways, with indication of a solvent regeneration mechanism. These findings are fortuitous for process development, as such a mechanism would be beneficial for process longevity and cost effectiveness.","PeriodicalId":21167,"journal":{"name":"Radiochimica Acta","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141503021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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