Vincent De Parades, Mohamed Amine Haouari, Nadia Fathallah, Lucas Spindler, Amélie Barré, Elise Pommaret, Paul Benfredj
Anal fistulas: SPARING THE SPHINCTER. Fistulotomy is the most used treatment for anal fistula. It is very effective with a cure rate of over 95% but carries a risk of incontinence. This has led to the development of various sphincter sparing techniques. The injection of biological glue or paste and the insertion of a plug have disappointing results and are expensive. The rectal advancement flap is still practised because of its cure rate of around 75% but it may result in some incontinence. Intersphincteric ligation of the fistula track and laser treatment are widely practised in France with cure rates between 60 and 70%. Video-assisted anal fistula treatment as well as injections of adipose tissue, stromal vascular fraction, platelet-enriched plasma and/or mesenchymal stem cells are emerging techniques for which even better results are expected.
{"title":"[Anal fistulas: Sparing the sphincter].","authors":"Vincent De Parades, Mohamed Amine Haouari, Nadia Fathallah, Lucas Spindler, Amélie Barré, Elise Pommaret, Paul Benfredj","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Anal fistulas: </strong>SPARING THE SPHINCTER. Fistulotomy is the most used treatment for anal fistula. It is very effective with a cure rate of over 95% but carries a risk of incontinence. This has led to the development of various sphincter sparing techniques. The injection of biological glue or paste and the insertion of a plug have disappointing results and are expensive. The rectal advancement flap is still practised because of its cure rate of around 75% but it may result in some incontinence. Intersphincteric ligation of the fistula track and laser treatment are widely practised in France with cure rates between 60 and 70%. Video-assisted anal fistula treatment as well as injections of adipose tissue, stromal vascular fraction, platelet-enriched plasma and/or mesenchymal stem cells are emerging techniques for which even better results are expected.</p>","PeriodicalId":21248,"journal":{"name":"Revue Du Praticien","volume":"73 3","pages":"274-278"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9606153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Émilie Liot, Frédéric Ris, Joan Robert-Yap, Guillaume Meurette
RECENT ADVANCES IN FECAL INCONTINENCE TREATMENT. Anal incontinence is a chronic condition that affects nearly 10% of the general population. When anal leakage concerns the stool and is frequent, the impact on the quality of life is very important. Recent advances in non-invasive medical treatments and in operative approaches make it possible to provide for most patients an anorectal comfort compatible with a social life. The three main challenges for the future lie in the organization of screening for this condition which is still taboo and for which patients do not easily confide, in a better selection of patients to offer the most suitable treatments, and therefore a better understanding of the pathophysiological mechanisms; and finally in the establishment of algorithms which prioritize treatments according to their side effects and their effectiveness.
{"title":"[Recent advances in fecal incontinence treatment].","authors":"Émilie Liot, Frédéric Ris, Joan Robert-Yap, Guillaume Meurette","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>RECENT ADVANCES IN FECAL INCONTINENCE TREATMENT. Anal incontinence is a chronic condition that affects nearly 10% of the general population. When anal leakage concerns the stool and is frequent, the impact on the quality of life is very important. Recent advances in non-invasive medical treatments and in operative approaches make it possible to provide for most patients an anorectal comfort compatible with a social life. The three main challenges for the future lie in the organization of screening for this condition which is still taboo and for which patients do not easily confide, in a better selection of patients to offer the most suitable treatments, and therefore a better understanding of the pathophysiological mechanisms; and finally in the establishment of algorithms which prioritize treatments according to their side effects and their effectiveness.</p>","PeriodicalId":21248,"journal":{"name":"Revue Du Praticien","volume":"73 3","pages":"296-299"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9599870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDENTIFICATION OF CUTANEOUS ADVERSE DRUG REACTIONS. Cutaneous adverse drug reactions are common. The most common are maculopapular exanthemas, which heal within a few days. However, clinical and biological signs of severity should be ruled out. Severe drug reactions include acute generalized exanthematous pustulosis, DRESS (drug reaction with eosinophilia and systemic symptoms), and epidermal necrolysis (Stevens-Johnson and Lyell syndromes). The search for the suspect drug is based on the questioning of the patient or his entourage and a chronological timeline. The treatment of drug eruption depends on its nosological type and the patient's background. For any severe drug reaction, hospitalization in a specialized units is necessary. Follow-up of epidermal necrolysis should be prolonged due to the frequency of disabling sequelae. All drug reactions, in particular the severe forms, must be declared to the pharmacovigilance services.
{"title":"[Identification of cutaneous adverse drug reactions].","authors":"Saskia Ingen-Housz-Oro","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>IDENTIFICATION OF CUTANEOUS ADVERSE DRUG REACTIONS. Cutaneous adverse drug reactions are common. The most common are maculopapular exanthemas, which heal within a few days. However, clinical and biological signs of severity should be ruled out. Severe drug reactions include acute generalized exanthematous pustulosis, DRESS (drug reaction with eosinophilia and systemic symptoms), and epidermal necrolysis (Stevens-Johnson and Lyell syndromes). The search for the suspect drug is based on the questioning of the patient or his entourage and a chronological timeline. The treatment of drug eruption depends on its nosological type and the patient's background. For any severe drug reaction, hospitalization in a specialized units is necessary. Follow-up of epidermal necrolysis should be prolonged due to the frequency of disabling sequelae. All drug reactions, in particular the severe forms, must be declared to the pharmacovigilance services.</p>","PeriodicalId":21248,"journal":{"name":"Revue Du Praticien","volume":"73 3","pages":"307-313"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9599882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Novelties in proctology].","authors":"Vincent De Parades, Aubert Manuel","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":21248,"journal":{"name":"Revue Du Praticien","volume":"73 3","pages":"269"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9760323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Novelties in proctology: 8 key messages].","authors":"Vincent De Parades","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":21248,"journal":{"name":"Revue Du Praticien","volume":"73 3","pages":"300"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9760327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}