Revue medicale suisse最新文献

Through the analysis of notable studies from 2024, this article offers an overview of key advances in internal medicine with a selection of essential themes. The topics covered include advances in common internal medicine conditions such as cardiovascular diseases, pulmonary disorders, antibiotic use, and fever of unknown origin. This article provides a practical summary to help clinicians stay informed about the latest diagnostic and therapeutic developments.

This article presents a selection of ten key topics, carefully analyzed and commented on by chief residents at the Department of Internal Medicine at CHUV. This curated selection highlights the major advances and essential reminders in internal medicine for 2024. By reviewing this year's leading publications, it sheds light on progress in diagnostic and therapeutic approaches, both for hospitalized patients and the continuity of care in outpatient settings. From diabetes to cardiology, including gender medicine and nephrology, each area is examined with a focus on clinical innovations. This retrospective provides practitioners with a valuable resource to stay up to date with the latest developments, helping to improve the quality of care delivered to patients.

Addiction medicine is confronting challenges brought about by changes in our modern world, including shifts in the drug market and the increasing digitalization of our environments. This article highlights some of these challenges and explores potential strategies to address them. The field is also advancing through robust research momentum in psychedelic-assisted psychotherapy. Additionally, the rapid growth of non-invasive brain stimulation techniques and artificial intelligence-driven research demonstrates the integration of cutting-edge technologies into addiction medicine, with the potential to transform clinical practice in the years ahead.

Joint hypermobility is a common feature in children and adolescents, often physiological and benign, but it is also a manifestation of hereditary connective tissue disorders. In pediatrics, there is a real need to differentiate Ehlers-Danlos syndrome (EDS) hypermobile type (hEDS) from benign hypermobility, in the absence of a genetic marker specific to this form of EDS. In 2023, the International Ehlers-Danlos Consortium revised the diagnostic criteria for children and adolescents, introducing the concept of hypermobility spectrum disorder. In line with these recommendations, the clinical criteria for hEDS established for adults do not apply in paediatrics, and hEDS should no longer be diagnosed before the age of biological maturity. At the end of the child's growth, a specialized reassessment is required, applying the 2017 hEDS criteria.

In this article, we look at a selection of recent developments in various areas of endocrinology. We focus on advances in endocrine pharmacotherapy and endocrine surgery, addressing several areas: a) the thyroid safety of Glucagon-Like Peptide-1 (GLP1) analogues; b) the efficacy of adrenal surgery for mild autonomous cortisol secretion; c) crinecerfont in the management of congenital adrenal hyperplasia in adults and children; d) paltusotin as a novel oral therapy for acromegaly and e) TransCon PTH (palopegteriparatide) as a novel therapy for chronic hypoparathyroidism.

Parkinson's disease affects around 6 million people worldwide. It causes both motor and non-motor symptoms. Since there is no cure, medical treatment aims to improve patients' quality of life. Combined with drug treatment, neurorehabilitation plays a major role in this field, thanks to its multidisciplinary approach. Practices such as physical therapy, Tai Chi, dance, and music therapy have shown positive results throughout the course of the disease. In addition, innovations such as augmented reality or specific treadmill training have interesting potential. However, further research is needed to refine therapeutic strategies and optimize the effectiveness of treatments.