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Des pratiques à risque favorisant la survenue d'abcès cutanés chez les personnes qui injectent des substances : résultats de l’étude ANRS-OUTSIDER 有利于注射药物的人皮肤脓肿发生的危险做法:ANRS局外人研究结果
IF 0.9 4区 医学 Q3 Medicine Pub Date : 2023-10-01 DOI: 10.1016/j.respe.2023.102142
Jessica Pereira Gonçalves , Laélia Briand Madrid , Cécile Donadille , David Michels , Mathieu Ahouah , Daniela Rojas Castro , Perrine Roux

Introduction

Cutaneous abscesses are a common complication of intravenous substance use. Although these skin and soft tissue infections represent one of the main causes of emergency room visits and hospitalizations in people who inject drugs (PWID), data on their prevalence and causes are scarce. The present study was part of the larger ANRS-OUTSIDER project and aimed to study the factors associated with skin abscesses in PWID, focusing in particular on the different stages of injection.

Method

Analyses were based on data of the 164 persons who regularly injected psychoactive substances participating in the French ANRS-OUTSIDER project. A face-to-face questionnaire collected data on sociodemographics, substance use, injection practices, and experience of skin abscesses in the previous six months. Factors associated with skin abscesses were studied using a logistic regression model.

Results

Of the 140 participants for whom abscess data were recorded at inclusion, 35% reported having a skin abscess in the previous six months. Factors associated with skin abscesses were: benefiting from universal health coverage (PUMA/CMU/AME) (Odd ratio (OR) = 0.28, confidence interval (CI) à 95%=0.08–0.99), finding the vein to inject by touch (OR=3.44, 95% CI=1.41–8.43) and licking the needle before injection (OR=5.16, 95% CI=1.10–24.30).

Conclusion

Our results highlight that skin abscesses were very frequent among the complications observed in our sample of French PWID, and that certain injection practices fostered their occurrence. These data will provide stakeholders with useful information to improve prevention and harm reduction messages for PWID.

皮肤脓肿是静脉药物使用的常见并发症。尽管这些皮肤和软组织感染是注射药物(PWID)患者急诊室就诊和住院的主要原因之一,但关于其患病率和原因的数据很少。本研究是更大的ANRS-OUTSIDER项目的一部分,旨在研究PWID中与皮肤脓肿相关的因素,特别关注注射的不同阶段。方法对参与法国ANRS-OUTSIDER项目的164名定期注射精神活性物质的患者的数据进行分析。一份面对面的问卷收集了过去六个月的社会人口统计、药物使用、注射实践和皮肤脓肿经历的数据。采用逻辑回归模型研究了与皮肤脓肿相关的因素。结果在纳入时记录了脓肿数据的140名参与者中,35%的人报告在前六个月内有皮肤脓肿。与皮肤脓肿相关的因素有:受益于全民健康保险(PUMA/CMU/AME)(比值比(OR)=0.28,置信区间(CI)à95%=0.08-0.99),通过触摸找到静脉注射(OR=3.44,95%CI=1.41–8.43)和在注射前舔针(OR=5.16,95%CI=1.10–24.30)。结论我们的结果强调,在我们的法国PWID样本中观察到的并发症中,皮肤脓肿非常常见,并且某些注射实践促进了其发生。这些数据将为利益相关者提供有用的信息,以改进PWID的预防和减少伤害信息。
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引用次数: 0
Editorial board / Ours rédaction 编辑板/我们的写作
IF 0.9 4区 医学 Q3 Medicine Pub Date : 2023-10-01 DOI: 10.1016/S0398-7620(23)00764-2
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引用次数: 0
Agenda 议程
IF 0.9 4区 医学 Q3 Medicine Pub Date : 2023-10-01 DOI: 10.1016/j.respe.2023.102144
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引用次数: 0
Doing a Systematic Review. A Student's Guide. Third Edition 进行系统审查。学生指南。第三版
IF 0.9 4区 医学 Q3 Medicine Pub Date : 2023-10-01 DOI: 10.1016/j.respe.2023.102145
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引用次数: 214
Evaluation of the severity of screened colorectal cancer in the context of the health crisis linked to COVID19 in Ile-de-France region Ile-de-France地区与COVID19相关的健康危机背景下癌症筛查严重程度的评估
IF 0.9 4区 医学 Q3 Medicine Pub Date : 2023-10-01 DOI: 10.1016/j.respe.2023.102124
Akoï Koïvogui , Gaëlle Abihsera , Tu Le Trong , Hamou Ait-Hadad , Agnès Bernoux , Hélène Delattre , Catherine Vincelet , Rachel Caroll , Jerôme Nicolet

Background

After the announcement in March 2020 of the COVID-19 pandemic, colorectal cancer (CRC) screening programs were suspended in several countries. Compared to the lesions detected during previous campaigns, this study aims to assess the severity of CRC detected during the 2020 screening campaign in Île-de-France, the French region most affected by the 1st wave of the pandemic.

Methods

The descriptive and etiological study included all faecal immunochemical test (FIT) results carried out between January 2017 and December 2020 on people aged 50–74, living in Île-de-France. First, the proportion of colonoscopies performed within one month (One-month-colo) following FIT; the yield of colonoscopy (proportion of colonoscopies with a neoplasm lesion among those performed) and CRC severity (TNM Classification, Level-0: T0/N0/M0, Level-1: T1/T2/N0/M0, Level-2: T3/T4/N0/M0; Level-3: T3/T4/N1/M0; Level-4: M1) were described in 2020 compared to previous campaigns (2017, 2018, and 2019). Subsequently, the link between the level of CRC severity and the predictive factors, including campaign year and time to colonoscopy, was analysed using polytomous multivariate regression.

Results

The one-month-colo (2017: 9.1% of 11,529 colonoscopies; 2018: 8.5% of 13,346; 2019: 5.7% of 7,881; 2020: 6.7% of 11,040; p < 0.001), the yield (65.2%, 64.1%, 62.4%, 60.8% respectively, p < 0.001) were significantly different between campaigns. The proportion of CRC level-4 (4.8% in 2017 (653 CRC); 7.6% in 2018 (674 CRC); 4.6% in 2019 (330 CRC) and 4.7% in 2020 (404 CRC); p < 0.29) was not significantly different between campaigns. The probability of having CRC with a high severity level was inversely related to the time to colonoscopy but not to the campaign year. Compared to patients having undergone colonoscopy within 30 days, the odds were significantly reduced by 60% in patients having undergone colonoscopy after 7 months (adjusted Odds-Ratio: 0.4 [0.3; 0.6]; p < 0.0001).

Conclusions

The French indicators were certainly degraded before the first wave of the COVID-19. The delay in access to colonoscopy as well as its extension induced by the COVID-19 crisis had no impact in terms of cancer severity, due to a discriminatory approach prioritizing patients with evident symptoms.

背景在2020年3月宣布新冠肺炎大流行后,几个国家暂停了癌症筛查项目。与之前活动中检测到的病变相比,本研究旨在评估2020年法兰西岛筛查活动中检测出的CRC的严重程度,法兰西岛是受第一波疫情影响最严重的法国地区。方法描述性和病原学研究包括2017年1月至2020年12月对居住在法兰西岛的50-74岁人群进行的所有粪便免疫化学测试(FIT)结果。首先,FIT后一个月内(结肠镜检查一个月)进行结肠镜检查的比例;与之前的活动(2017年、2018年和2019年)相比,描述了2020年结肠镜检查的产量(结肠镜检查中肿瘤病变的比例)和CRC严重程度(TNM分类,0级:T0/N0/M0,1级:T1/T2/N0/M0,2级:T3/T4/N0/M0;3级:T3/T4/N1/M0;4级:M1)。随后,使用多元多元回归分析CRC严重程度与预测因素之间的联系,包括活动年份和结肠镜检查时间。结果一个月结肠镜检查(2017年:11529次结肠镜检查中的9.1%;2018年:13346次结肠镜检中的8.5%;2019年:7881次结肠镜检测中的5.7%;2020年:11040次结肠镜筛查中的6.7%;p<0.001)、产率(分别为65.2%、64.1%、62.4%、60.8%,p>0.001)在不同活动之间存在显著差异。CRC四级比例(2017年4.8%(653 CRC);2018年7.6%(674 CRC);2019年为4.6%(330 CRC),2020年为4.7%(404 CRC);p<;0.29)之间没有显著差异。CRC严重程度高的概率与结肠镜检查的时间呈负相关,但与活动年份无关。与30天内接受结肠镜检查的患者相比,7个月后接受结肠镜治疗的患者的发病率显著降低了60%(调整后的比值比:0.4[0.3;0.6];p<;0.0001)。新冠肺炎危机导致的结肠镜检查延迟及其延长对癌症严重程度没有影响,因为歧视性方法优先考虑症状明显的患者。
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引用次数: 0
Sommaire Sommaire
IF 0.9 4区 医学 Q3 Medicine Pub Date : 2023-10-01 DOI: 10.1016/S0398-7620(23)00763-0
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引用次数: 0
Évaluation d'un protocole d'orientation vers le droit commun parmi des patients ayant été suivis en permanence d'accès aux soins de santé suite à une hospitalisation 评估住院后持续接受医疗服务的患者的普通法转诊方案。
IF 0.9 4区 医学 Q3 Medicine Pub Date : 2023-10-01 DOI: 10.1016/j.respe.2023.102125
J. Khouani , M. Jaillard , E. Launay , S. Del Duca , G. Guarinos , J. Borlot , P. Auquier , C. Tabélé

Introduction

PASS is a hospital care unit that provides access to health care for precarious persons and supports them as soon as they have obtained primary health care insurance. No details of this support had previously been described. A Hospital-to-Community protocol for referral to the public health system has been developed at the adult PASS unit of the Marseille public hospitals (AP-HM). The objectives of this study are to describe how this protocol is applied, to evaluate at six months the inclusion in general practice of patients having benefited (or not) from this protocol and to determine the key influencing factors.

Material and method

This two-arm prospective observational study collected data on the primary care pathways of precarious patients six months after their having obtained health coverage, and found out whether or not the newly existing protocol had been effectively implemented. It was carried out on a cohort of people included in the PASS-MULTI study who had acquired complete health coverage.

Results

Sixty patients were included between November 2020 and August 2022, 35 of whom had availed themselves of the Hospital-to-Community protocol. Among them, 68.8% in the interventional group had consulted their referring general practitioner within six months, vs. 40% in the control group (p = 0.04). The initiation of follow-up in general medicine was associated with application of the protocol (p = 0.04).

Conclusion

This study described an initial Hospital-to-Community protocol for referral to the primary healthcare system of patients followed up in the PASS unit and found an association between application of this protocol and initiation of follow-up in primary healthcare.

简介PASS是一个医院护理单位,为不稳定的人提供医疗服务,并在他们获得初级医疗保险后立即为他们提供支持。此前没有对这种支持的细节进行描述。马赛公立医院(AP-HM)的成人PASS部门制定了一项转诊到公共卫生系统的医院到社区协议。本研究的目的是描述如何应用该方案,在六个月时评估从该方案中受益(或未受益)的患者是否纳入全科医学,并确定关键影响因素。材料和方法这项两臂前瞻性观察性研究收集了不稳定患者在获得医疗保险六个月后的初级保健途径数据,并了解了新存在的方案是否得到了有效实施。这项研究是对PASS-MULTI研究中获得完全健康保险的一组人进行的。结果在2020年11月至2022年8月期间,共有60名患者,其中35人使用了医院到社区方案。其中68.8%的介入组在6个月内咨询过转诊的全科医生,对照组为40%(p=0.04)。普通医学随访的开始与方案的应用有关(p=0.04在初级保健领域。
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引用次数: 0
Determinants of health-related quality of life among adolescents: The role of the Mediterranean diet 青少年健康相关生活质量的决定因素:地中海饮食的作用
IF 0.9 4区 医学 Q3 Medicine Pub Date : 2023-10-01 DOI: 10.1016/j.respe.2023.102148
Rosy Mitri , Sara Khalife , Fouad Ziade

Background

A number of physical, emotional, cognitive and psychological changes shape the adolescence phase, which may influence health and well-being. Therefore, it is important to develop healthy eating habits that will persist into adulthood.

Objective

This study was conducted in order to investigate in depth the association between components of the Mediterranean diet (MD) and health-related quality of life (HRQoL), along with its different subscales, among Lebanese adolescent students attending schools in Tripoli, North Lebanon.

Methods

A cross-sectional survey was undertaken among 798 teenagers aged 11 to 18. All responded to a questionnaire that evaluated their HRQoL, sociodemographic characteristics and adherence to the Mediterranean diet.

Results

The results of the study revealed that only 15.9% of the students had a high adherence to the MD. With regard to the components of the MD associated with the HRQoL, it was revealed that fruit intake by the students (once daily) was associated with a better general well-being (P = 0.047). In addition, fish consumption (two to three times per week) and daily intake of a dairy product for breakfast were positively associated with the total KIDSCREEN score (P < 0.001 and P = 0.003, respectively). Finally, skipping breakfast was correlated with a poorer general well-being (P = 0.013).

Conclusion

Our results suggest a strong correlation between MD adherence and HRQoL in Lebanese adolescents. However, future studies are warranted in order to strengthen the evidence of this association.

背景许多生理、情感、认知和心理方面的变化塑造了青春期,这些变化可能会影响健康和幸福。因此,养成健康的饮食习惯是很重要的,这种习惯将持续到成年。目的本研究旨在深入调查在黎巴嫩北部的黎波里上学的黎巴嫩青少年学生中地中海饮食(MD)成分与健康相关生活质量(HRQoL)及其不同分量表之间的关系。方法对798名11~18岁的青少年进行横断面调查。所有人都回答了一份问卷,该问卷评估了他们的HRQoL、社会人口学特征和对地中海饮食的坚持程度。结果研究结果显示,只有15.9%的学生对MD有很高的依从性。就与HRQoL相关的MD成分而言,学生摄入水果(每天一次)与更好的总体幸福感相关(P=0.047)。此外,鱼类消费量(每周两到三次)和早餐乳制品的每日摄入量与KIDSCREEN总分呈正相关(分别为P<;0.001和P=0.003)。最后,不吃早餐与总体幸福感较差相关(P=0.013)。结论我们的研究结果表明,黎巴嫩青少年MD依从性与HRQoL之间存在很强的相关性。然而,为了加强这种关联的证据,未来的研究是有必要的。
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引用次数: 0
Homogeneous age mixing in Ebola case-contact : A retrospective study in Guinea 埃博拉病例接触的同质年龄混合:几内亚的一项回顾性研究。
IF 0.9 4区 医学 Q3 Medicine Pub Date : 2023-10-01 DOI: 10.1016/j.respe.2023.102143
Jean-François Etard, Mamadou Saliou Sow, Cécé Kpamou, Eric Delaporte, Abdoulaye Touré
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引用次数: 0
Analyse de l'hypertension en France : pour une analyse intersectionnelle de la cascade de soins 法国高血压分析:护理级联的交叉分析
IF 0.9 4区 医学 Q3 Medicine Pub Date : 2023-09-18 DOI: 10.1016/j.respe.2023.102159
L. Silberzan , M. Kelly-Irving , N. Bajos

In metropolitan France, estimates suggest that more than one in three adults has hypertension. Low-cost treatments are available, yet fewer than one in four hypertensive adults has a controlled level of hypertension below 140/90 mmHg. This rate is higher in other high-income countries such as Canada (65%) or Germany (52%).  Using a ‘cascade of care’ model, that decomposes the hypertension care continuum in awareness, treatment, and control, provides a better understanding of the origins of poor control. Furthermore, the theoretical framework of intersectionality, which simultaneously considers social positions of gender, class, and ethno-racial origin, could be used to understand the complexity of the social inequalities observed in hypertension-related outcomes. In this article we conducted a critical review of the international literature to identify new lines of analyses that could be applied to examine complex inequalities in France.

据估计,在法国大城市,超过三分之一的成年人患有高血压。可以获得低成本的治疗,但只有不到四分之一的高血压成年人的高血压控制水平低于140/90毫米汞柱。这一比例在其他高收入国家更高,如加拿大(65%)或德国(52%)。使用“级联护理”模型,将高血压护理的连续性分解为意识、治疗和控制,可以更好地了解控制不良的根源。此外,交叉性的理论框架同时考虑了性别、阶级和种族出身的社会地位,可以用来理解在高血压相关结果中观察到的社会不平等的复杂性。在这篇文章中,我们对国际文献进行了批判性的回顾,以确定可用于研究法国复杂不平等的新的分析路线。
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引用次数: 0
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Revue D Epidemiologie Et De Sante Publique
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