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From rural Norway to high-density systems: translating nurse-led emergency models. 从挪威农村到高密度系统:翻译护士主导的急救模式。
IF 1.9 3区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-06-23 DOI: 10.1080/02813432.2025.2524367
Yalcin Golcuk
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引用次数: 0
Facilitating access to mental healthcare for patients with long-term conditions in general practice: a qualitative collective case study. 在一般实践中促进长期疾病患者获得精神保健:定性集体案例研究。
IF 1.8 3区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-06-11 DOI: 10.1080/02813432.2025.2516497
Amanda Nikolajew Rasmussen, Viola Burau, Helle Terkildsen Maindal

Objective: Mental health problems among patients with type 2 diabetes (T2D) and ischemic heart disease (IHD) are common, but often undertreated. General practice is a relevant setting for addressing this complex health condition. However, research suggests that this group of patients often experience problems accessing care. This study aimed to explore how access to mental healthcare in general practice for patients with T2D and/or IHD is facilitated by processes of organizing care.

Design, setting and participants: The study was designed as a qualitative collective case study in four general practices in Central Denmark Region participating in The Healthy Mind Study. Data were collected through ethnographic observations of, and qualitative interviews with patients and healthcare professionals.

Results: We found that when healthcare professionals adapted services to specific patient needs, the patients felt welcome and accepted. Furthermore, finding a balance between letting the patient take responsibility while still providing sufficient support led to patients feeling empowered while still feeling cared for. Organizational prioritization of patients in vulnerable situations created circumstances that enabled healthcare professionals to provide better access to care and better treatment outcomes.

Conclusion: Healthcare professionals in general practice must think about their role in facilitating access to mental healthcare. An important part of this is that general practices prioritize patients in vulnerable situations, for example through specialized services, outreach work, structured staff supervision, and extra time. Recruitment of participants for mental healthcare interventions in general practice may benefit from using informal strategies relying on the patient-provider relationship.

目的:2型糖尿病(T2D)和缺血性心脏病(IHD)患者的心理健康问题是常见的,但往往治疗不足。一般做法是解决这一复杂健康状况的相关设置。然而,研究表明,这组患者经常遇到获得护理的问题。本研究旨在探讨如何通过组织护理过程促进T2D和/或IHD患者在一般实践中获得精神卫生保健。设计、环境和参与者:本研究被设计为一项定性的集体案例研究,涉及丹麦中部地区参加健康心理研究的四个全科诊所。通过对患者和医疗保健专业人员的人种学观察和定性访谈收集数据。结果:我们发现,当医疗保健专业人员调整服务,以特定的病人需要,病人感到欢迎和接受。此外,在让病人承担责任和提供足够的支持之间找到一个平衡,会让病人感到自己被赋予了权力,同时仍然感到被照顾。组织对u型患者的优先排序创造了环境,使医疗保健专业人员能够提供更好的护理和更好的治疗结果。结论:全科医疗保健专业人员必须考虑他们在促进获得精神卫生保健方面的作用。这方面的一个重要部分是,全科实践优先考虑弱势患者,例如通过专门服务、外展工作、有组织的工作人员监督和额外时间。在全科实践中招募精神卫生保健干预的参与者可能受益于使用依赖于患者-提供者关系的非正式策略。
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引用次数: 0
Cognitive dysfunction in diabetes - the 'forgotten' diabetes complication: a narrative review. 糖尿病的认知功能障碍——“被遗忘的”糖尿病并发症:叙述性回顾。
IF 1.9 3区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-06-01 Epub Date: 2025-01-28 DOI: 10.1080/02813432.2025.2455136
Åke Sjöholm, Louise Bennet, Peter M Nilsson

Background: In addition to peripheral neuropathy of various kinds, diabetes can also cause central neuropathy, which among other things can manifest itself as premature cognitive dysfunction, often linked to vascular dysfunction. Although the link between diabetes and cognitive dysfunction was discovered more than 100 years ago and has important clinical implications, this diabetes complication remains relatively unknown. Recent years have seen research that has clarified cerebral insulin resistance and defective insulin signaling as examples of pathogenic factors behind this cognitive impairment in diabetes.

Method: We provide a narrative review of select and contemporary publications with relevance for the interface between diabetes/prediabetes and cognitive function.

Results: Recently published studies show that physical activity can reverse insulin resistance in the brain as well as cognitive impairment and pathological appetite regulation. Pharmacological interventions with, for example, nasal insulin, GLP-1 receptor agonists, SGLT-2 inhibitors, or PPAR-γ agonists have also shown promising results.

Conclusion: Optimization of lifestyle factors (e.g. physical activity), as well as several pharmaceutical agents already in clinical use against diabetes, have shown promising results in improving cognitive function in diabetic patients. An important task for primary health care, where most patients with type 2 diabetes are diagnosed, treated, and followed, is to increase awareness and early detection of cognitive dysfunction in these patients for optimizing risk factor control.

背景:除了各种周围神经病变外,糖尿病还可引起中枢神经病变,其表现为过早的认知功能障碍,通常与血管功能障碍有关。虽然糖尿病和认知功能障碍之间的联系早在100多年前就被发现,并且具有重要的临床意义,但这种糖尿病并发症仍然相对未知。近年来的研究表明,脑胰岛素抵抗和胰岛素信号缺陷是糖尿病认知障碍背后的致病因素。方法:我们提供了一个关于糖尿病/前驱糖尿病和认知功能之间的接口的选择和当代出版物的叙述性回顾。结果:最近发表的研究表明,体育活动可以逆转大脑中的胰岛素抵抗,以及认知障碍和病理性食欲调节。药物干预,例如鼻用胰岛素、GLP-1受体激动剂、SGLT-2抑制剂或PPAR-γ激动剂也显示出有希望的结果。结论:优化生活方式因素(如体力活动),以及一些已经在临床上用于治疗糖尿病的药物,在改善糖尿病患者认知功能方面显示出良好的效果。对于大多数2型糖尿病患者进行诊断、治疗和随访的初级卫生保健来说,一项重要任务是提高对这些患者认知功能障碍的认识和早期发现,以优化风险因素控制。
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引用次数: 0
Differences in use of telemedicine integrated into traditional primary health care - a comparative observational study. 将远程医疗纳入传统初级卫生保健的使用差异——一项比较观察研究。
IF 1.9 3区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-06-01 Epub Date: 2025-02-06 DOI: 10.1080/02813432.2025.2457542
Pär Eriksson, Maria Randjelovic, Hans Thulesius, Tora Hammar, Stefan Lagrosen, Evalill Nilsson

Telemedicine in primary health care is expected to address many of the issues currently challenging service delivery. However, the impact and effect will depend on who will use the new technology.

Objective: The objective of the study was to investigate differences between users and non-users of telemedicine integrated into traditional office-based primary health care.

Methods: Quantitative registry-based population study in two regions in the southeast part of Sweden (n = 73,486), comparing users with non-users of telemedicine across the variables sex, age, socioeconomic status (SES), morbidity and health care seeking behaviour (HSB). Two study periods of six months were used (September 2019-February 2020 for Region Östergötland, and September 2021-February 2022 for Region Kalmar County) to collect user data. A reference period of 36 months (September 2016-August 2019) was used, to collect data on HSB.

Results: Users were more often women under the age of 60 and had higher morbidity (measured as resource utilisation) than non-users (p < .001). In contrast, no statistically significant differences were seen between the two groups regarding SES, measured as Care Need Index (CNI). Regarding HSB, a proxy measure (health record entries) showed more entries for users than non-users.

Conclusions: Our findings suggest that users are more likely to be women and below the age of 60. Likewise, users also tend to have a greater need for health care services compared to non-users, and they seek health care more often compared to non-users. No differences regarding SES were found.

初级卫生保健中的远程医疗预计将解决目前挑战服务提供的许多问题。然而,影响和效果将取决于谁将使用这项新技术。目的:本研究的目的是调查将远程医疗纳入传统办公室初级卫生保健的用户和非用户之间的差异。方法:在瑞典东南部的两个地区(n = 73,486)进行基于定量登记的人口研究,比较远程医疗用户和非用户在性别、年龄、社会经济地位(SES)、发病率和求医行为(HSB)等变量。使用两个为期六个月的研究期(Östergötland地区为2019年9月至2020年2月,卡尔玛县地区为2021年9月至2022年2月)收集用户数据。参考期为36个月(2016年9月- 2019年8月),用于收集HSB数据。结果:用户通常是60岁以下的女性,发病率(以资源利用率衡量)高于非用户(p结论:我们的研究结果表明,用户更有可能是60岁以下的女性。同样,与非使用者相比,使用者也往往对保健服务有更大的需求,与非使用者相比,他们寻求保健服务的频率更高。在SES方面没有发现差异。
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引用次数: 0
Systematic Coronary Risk Evaluation 2 (SCORE2), arterial stiffness, and subclinical coronary atherosclerosis in a population-based study. 系统性冠状动脉风险评估2 (SCORE2)、动脉硬度和亚临床冠状动脉粥样硬化在一项基于人群的研究中。
IF 1.9 3区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-06-01 Epub Date: 2025-01-24 DOI: 10.1080/02813432.2025.2456948
Susanna Strömberg, Andreas Stomby, Jan Engvall, Carl Johan Östgren

Aim: To investigate the association between Systematic Coronary Risk Evaluation 2 (SCORE2) and subclinical damage in two vascular beds: atherosclerosis in the coronary arteries and aortic arterial stiffness, in a large population-based cohort without cardiovascular disease or diabetes.

Methods: Design: A cross-sectional study based on Swedish CArdio Pulmonary bioImaging Study (SCAPIS) data. Study population: A population-based cohort of 3087 participants aged 50-64.

Outcome: Pulse Wave Velocity (PWV) was measured, and aortic arterial stiffness was defined as PWV≥ 10 m/s. Coronary artery calcium score (CACS) was determined by coronary computed tomography and clinically significant coronary calcification was defined as CACS > 100.

Results: The prevalence of arterial stiffness was 6.6% in the low-moderate SCORE2 risk group, 31.0% in the high-risk group, and 53.3% in the very high-risk group. The prevalence of coronary calcification was 4.5%, 18.5% 23.0%, respectively. There was a modest overlap between arterial stiffness and coronary calcification in all SCORE2 risk groups. When comparing the high SCORE2 risk group with the low-moderate risk group, the Odds ratio (OR) was 6.4, 95% confidence interval (CI 5.1-8.0) for arterial stiffness and 4.8 (CI 3.7-6.3) for coronary calcification. When comparing the very high SCORE2 risk group to the low-moderate group, the OR was 16.2 (CI 11.3-23.1) for arterial stiffness and 6.4 (CI 4.2-9.7) for coronary calcification.

Conclusion: Our study shows that high cardiovascular risk according to SCORE2 is associated with increased arterial stiffness and significant coronary calcification in a population without prevalent cardiovascular disease or diabetes. This knowledge can be useful in primary care, where SCORE2 is frequently used as a risk prediction tool. The modest overlap between arterial stiffness and coronary calcification suggests that CACS and PWV describe different types of vascular damage.

目的:在无心血管疾病或糖尿病的大型人群队列中,研究系统性冠状动脉风险评估2 (SCORE2)与两种血管床亚临床损害的关系:冠状动脉粥样硬化和主动脉硬化。方法:设计:基于瑞典心肺生物成像研究(SCAPIS)数据的横断面研究。研究人群:3087名年龄在50-64岁之间的人群为基础的队列。结果:测量脉搏波速度(Pulse Wave Velocity, PWV),以PWV≥10m /s定义主动脉僵硬度。冠状动脉计算机断层扫描测定冠状动脉钙化评分(CACS),将临床上明显的冠状动脉钙化定义为CACS bbb100。结果:低中度SCORE2危险组动脉硬化发生率为6.6%,高危组为31.0%,高危组为53.3%。冠状动脉钙化患病率分别为4.5%、18.5%、23.0%。在所有SCORE2危险组中,动脉僵硬和冠状动脉钙化之间存在适度的重叠。当比较高SCORE2风险组与中低风险组时,动脉僵硬的优势比(OR)为6.4,95%可信区间(CI 5.1-8.0),冠状动脉钙化的优势比(OR)为4.8 (CI 3.7-6.3)。当将非常高的SCORE2风险组与低中度风险组进行比较时,动脉僵硬的OR为16.2 (CI 11.3-23.1),冠状动脉钙化的OR为6.4 (CI 4.2-9.7)。结论:我们的研究表明,根据SCORE2,在没有流行心血管疾病或糖尿病的人群中,高心血管风险与动脉僵硬度增加和明显的冠状动脉钙化有关。这些知识在初级保健中是有用的,在初级保健中SCORE2经常被用作风险预测工具。动脉硬化和冠状动脉钙化之间的适度重叠表明CACS和PWV描述了不同类型的血管损伤。
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引用次数: 0
Evaluating general practitioners' focused lung ultrasound competence and findings in patients with suspected community-acquired pneumonia in general practice. 评估全科医生对疑似社区获得性肺炎患者的重点肺部超声能力和结果。
IF 1.9 3区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-06-01 Epub Date: 2024-12-30 DOI: 10.1080/02813432.2024.2447083
Julie Jepsen Strøm, Camilla Aakjær Andersen, Martin Bach Jensen, Janus Laust Thomsen, Christian B Laursen, Søren Helbo Skaarup, Hans Henrik Lawaetz Schultz, Malene Plejdrup Hansen

Objectives: To evaluate general practitioners' (GPs') ability to perform focused lung ultrasound (FLUS) following a training program and assess FLUS feasibility in general practice. Also, to describe FLUS findings and evaluate GPs' ability to interpret these in adults with acute lower respiratory tract infection (LRTI) when pneumonia is suspected and assess GPs' perception of FLUS impact.

Methods: Nine GPs, using point-of-care ultrasound, completed a FLUS training program. Adults (≥ 18 years) with acute cough (< 28 days) and at least one other symptom of acute LRTI, where the GP suspected pneumonia, were subsequently included. All patients received FLUS. The GPs reported FLUS findings, feasibility, and perception of FLUS impact. Recorded FLUS videos from all patients were reviewed by two specialists (Specialist Reference). The specialists assessed FLUS image quality. Agreements between the GPs and the Specialist Reference on FLUS findings were used to evaluate GPs' ability to interpret FLUS.

Results: Of 91 patients included, FLUS image quality was acceptable or higher in 84 patients (92.4%). FLUS proved feasible with only two scans not completed. The GPs reported FLUS pathological findings in 51.7% of patients in 78% agreement with the Specialist Reference and Cohen's kappa 0.56. Focal B-lines represented the most frequent pathological findings. The GPs perceived that FLUS impacted change in tentative diagnosis and/or plans for treatment and/or visitation in 29 (32.0%) of patients.

Conclusion: After the training, the GPs performed FLUS well. Interpretation of FLUS pathology presence was of moderate agreement. The GPs perceived that FLUS had impact on patient management.

Trial registration number: ClinicalTrials.gov NCT04711031.

目的:评估全科医生(gp)在培训计划后进行聚焦肺超声(FLUS)的能力,并评估FLUS在全科实践中的可行性。此外,描述流感的发现并评估全科医生在怀疑患有肺炎的成人急性下呼吸道感染(LRTI)患者中解释这些发现的能力,并评估全科医生对流感影响的感知。方法:9名全科医生,使用即时超声,完成了流感培训计划。随后纳入急性咳嗽(< 28天)和至少一种急性下呼吸道感染其他症状的成年人(≥18岁),其中全科医生怀疑为肺炎。所有患者都接受了流感治疗。gp报告了流感病毒的发现、可行性和流感病毒影响的看法。两名专家审查了所有患者录制的流感视频(专家参考)。专家们评估了FLUS的图像质量。全科医生和专家参考之间关于流感诊断结果的协议被用来评估全科医生解释流感的能力。结果:在纳入的91例患者中,84例(92.4%)患者的FLUS图像质量可接受或更高。fluus被证明是可行的,只有两次扫描未完成。全科医生报告了51.7%的患者的FLUS病理发现,78%与专科参考文献和Cohen的kappa 0.56一致。局灶b线是最常见的病理表现。全科医生认为流感影响了29名(32.0%)患者的初步诊断和/或治疗计划和/或探视计划的改变。结论:经过培训,全科医生的FLUS表现良好。对流感病理表现的解释是中度一致的。全科医生认为流感对病人管理有影响。试验注册号:ClinicalTrials.gov NCT04711031。
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引用次数: 0
Health-related quality of life, lifestyle habits and chronic pain in individuals with knee pain - a 2-year follow-up study. 与健康相关的生活质量、生活习惯和膝关节疼痛患者的慢性疼痛——一项为期2年的随访研究
IF 1.9 3区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-06-01 Epub Date: 2025-01-20 DOI: 10.1080/02813432.2025.2452916
Charlotte Sylwander, Emma Haglund, Ingrid Larsson, Maria L E Andersson

Introduction: Knee pain increases the risk of developing chronic widespread pain (CWP) and knee osteoarthritis (KOA). The prevalence of CWP and KOA has increased, and there is a need for early prevention. Therefore, the aim was to examine the associations of health-related quality of life (HRQoL) and lifestyle habits with chronic pain at a two-year follow-up in individuals with knee pain.

Methods: A two-year longitudinal cohort study including 251 individuals aged 30-60 years reporting knee pain at baseline. HRQoL was measured via the Short-Form General Health Survey (SF-36), and lifestyle habits included questions on overweight, physical activity, diet, alcohol and tobacco use. Pain was assessed with a pain mannequin. Differences in health status and lifestyle habits over time in groups with unchanged no chronic pain (NCP), transitioned to less and more pain, and unchanged CWP were analysed using Wilcoxon's, McNemar's and Friedman's tests. Multinominal regression analysis was performed to study associations with reporting chronic pain at follow-up.

Results: Reporting better HRQoL across various SF-36 concepts and normal weight at baseline was associated with reporting NCP after two years. A few changes were made regarding HRQoL and lifestyle habits over the course of two years, but an increase in general health was associated with transitioning to less pain.

Conclusions: During primary care visits for knee pain with a combination of overweight or lower HRQoL, individuals should receive comprehensive attention to prevent the development of CWP. Future studies should investigate the associations further.

膝关节疼痛增加发展为慢性广泛性疼痛(CWP)和膝关节骨关节炎(KOA)的风险。CWP和KOA的患病率有所增加,需要进行早期预防。因此,本研究的目的是研究与健康相关的生活质量(HRQoL)和生活习惯与慢性疼痛的关系,对患有膝关节疼痛的个体进行为期两年的随访。方法:一项为期两年的纵向队列研究,包括251名年龄在30-60岁之间的人,他们在基线时报告膝关节疼痛。HRQoL通过简短一般健康调查(SF-36)进行测量,生活习惯包括超重、体育活动、饮食、酒精和烟草使用等问题。用疼痛模型评估疼痛。采用Wilcoxon's、McNemar's和Friedman's测试分析无慢性疼痛(NCP)、疼痛程度和疼痛程度过渡以及CWP不变组的健康状况和生活习惯随时间的差异。采用多项回归分析研究随访时报告慢性疼痛的相关性。结果:两年后报告不同SF-36概念的较好HRQoL和基线正常体重与报告NCP相关。在两年的过程中,在HRQoL和生活习惯方面做出了一些改变,但总体健康状况的改善与向疼痛减轻的过渡有关。结论:在对伴有超重或HRQoL较低的膝关节疼痛进行初级保健就诊时,个人应得到全面关注,以预防CWP的发展。未来的研究应进一步调查这些关联。
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引用次数: 0
'You would rather not fill your body with pills'-patient perspectives on polypharmacy and medication reviews by pharmacists in general practice. “你宁愿不要用药片填满你的身体”——病人对综合用药的看法和药剂师在一般实践中的用药评论。
IF 1.9 3区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-06-01 Epub Date: 2025-01-13 DOI: 10.1080/02813432.2025.2451660
Josefine Graabæk Als, Janus Laust Thomsen, Sabrina Storgaard Sørensen, Søren Paaske Johnsen, Camilla Hoffmann Merrild

Introduction: Polypharmacy is widespread. The demographic shift toward older patients receiving multiple medications increases risk and drug-related problems in these patients.

Objective: To investigate patient perspectives on polypharmacy and the experienced effects of medication reviews by pharmacists in general practice.

Methods: Twenty-two semi-structured interviews with patients with polypharmacy (>5 medications) from 6 different general practice clinics in the North Denmark region. The interviewees were from the intervention arm of a randomized clinical trial and had received a medication review with a pharmacist in addition to the usual annual check-up in general practice. Participants were interviewed at baseline (no later than 2 weeks after the medication review) and again at follow-up (6 months after the medication review). The interviews were transcribed verbatim and thematically analyzed with an inductive approach.

Results: The patients' narratives show that they face many difficulties in their everyday lives, making it hard for them to live up to society's ideal of what it is to live a healthy life. The interviewees were generally positive toward the intervention and felt comfortable having a pharmacist conduct the medication review in their usual general practice clinic. Some interviewees gained more insight into their medication from the review.

Conclusion: Patient narratives give a comprehensive understanding of the challenges of polypharmacy. Having pharmacists conduct medication reviews in general practice could ensure more time and focus on patients and their medication management. The combined knowledge of physicians, nurses, and pharmacists regarding thorough polypharmacy management is recommended.

介绍:多药制是普遍存在的。人口结构向接受多种药物治疗的老年患者的转变增加了这些患者的风险和药物相关问题。目的:了解患者对综合用药的看法及全科药师对综合用药的点评效果。方法:对来自北丹麦地区6个不同全科诊所的22例使用多种药物(bbb50种药物)的患者进行半结构化访谈。受访者来自随机临床试验的干预组,除了常规的年度检查外,还接受了药剂师的药物审查。在基线时(不迟于药物评估后2周)和随访时(药物评估后6个月)对参与者进行访谈。访谈被逐字记录下来,并用归纳方法对主题进行分析。结果:患者的叙述表明,他们在日常生活中面临许多困难,使他们很难达到社会对健康生活的理想。受访者普遍对干预持积极态度,并对在他们通常的全科诊所由药剂师进行药物审查感到满意。一些受访者从评论中对他们的药物有了更多的了解。结论:患者的叙述对多药治疗的挑战有了全面的了解。让药剂师在全科实践中进行药物审查可以确保更多的时间和关注患者及其药物管理。建议医生、护士和药剂师在综合药房管理方面的综合知识。
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引用次数: 0
Considerations and experiences with healthcare-seeking during the first COVID-19 lockdown in Denmark. 在丹麦首次COVID-19封锁期间寻求医疗保健的考虑和经验。
IF 1.9 3区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-06-01 Epub Date: 2025-01-20 DOI: 10.1080/02813432.2025.2452924
Isabella Raasthøj Holst, Lisa Maria Sele Sætre, Gitte Bruun Lauridsen, Kirubakaran Balasubramaniam, Peter Haastrup, Sonja Wehberg, Dorte Ejg Jarbøl

Aim: To (1) examine considerations before and experiences with GP contact during the first COronaVIrus Disease 2019 (COVID-19) lockdown among Danish citizens; (2) analyse the associations with sex, age, chronic disease, and socioeconomic factors; and (3) explore changes in healthcare-seeking behaviour post-pandemic.

Method: A total of 100,000 Danes aged 20 years or older, randomly selected in the general population, were invited to participate in a survey examining considerations and experiences with healthcare seeking during the first COVID-19 lockdown. Data were collected in spring 2022 and linked to register data on socioeconomic factors. Descriptive statistics and multivariable logistic regression models were applied.

Results: Of the 27,369 eligible individuals, 18% reported a need to contact their GP. Being worried about burdening the healthcare system was most frequently reported (45%), followed by being in doubt about acceptable contact reasons (33%), and concern about infection (24%). Although 44% of those who needed to contact their GP found the digital solutions advantageous, individuals frequently found it difficult to discuss symptoms by telehealth (29%) and that they were examined less thoroughly. Generally, women, younger people, and individuals with lower socioeconomic status were more likely to be worried and report difficulties with contact to general practice. Some 86% of the respondents reported no changes in healthcare-seeking behaviour post-pandemic.

Conclusion: The results may assist in the organisation of healthcare in case of future lockdowns. Yet, the COVID-19 pandemic has only slightly affected the healthcare-seeking behaviour in the Danish general population.

目的:(1)研究丹麦公民在首次冠状病毒病2019 (COVID-19)封锁期间与全科医生接触之前的考虑因素和经验;(2)分析与性别、年龄、慢性病和社会经济因素的关系;(3)探讨大流行后求医行为的变化。方法:从普通人群中随机抽取10万名20岁及以上的丹麦人,参与一项调查,调查在首次COVID-19封锁期间就医的考虑和经验。数据于2022年春季收集,并与社会经济因素的登记数据相关联。采用描述性统计和多变量logistic回归模型。结果:在27,369名符合条件的个人中,18%的人报告需要联系他们的全科医生。最常见的报告是担心给医疗保健系统增加负担(45%),其次是怀疑可接受的接触原因(33%),以及担心感染(24%)。尽管需要联系全科医生的人中有44%认为数字解决方案是有利的,但个人经常发现很难通过远程医疗讨论症状(29%),而且他们的检查不太彻底。一般来说,女性、年轻人和社会经济地位较低的人更有可能担心,并报告与全科医生联系有困难。约86%的答复者报告大流行后寻求医疗保健的行为没有变化。结论:本研究结果可为今后疫情防控工作提供参考。然而,2019冠状病毒病大流行对丹麦普通人群的就医行为只产生了轻微影响。
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引用次数: 0
Patients' experiences with GLP1-RAs - a systematic review. GLP1-RAs患者的经历——一项系统综述。
IF 1.8 3区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-06-01 Epub Date: 2025-03-12 DOI: 10.1080/02813432.2025.2477141
Christoffer Kraul Ibsen, Marius Brostrøm Kousgaard, Sofie Olsen, Ann-Kathrin Lindahl Christiansen, Catharina Thiel Sandholdt, Rasmus Rørth, Gritt Overbeck

Background: Obesity is a complex condition and a recognized public health challenge. Previous treatment options were associated with high failure rates, but recent trials have shown that significant weight loss can be achieved with GLP1-RAs. However, little is known about the patient's experiences with GLP1-RAs.

Objectives: This paper systematically reviews research on patients' experience with GLP1-RAs.

Methods: A literature search in PubMed, PsycINFO, Embase and Sociological Abstracts included studies on adults' experiences with GLP1-RAs, regardless of methodology. Exclusions of studies: mental illness, pregnancy, former bariatric surgery, PCOS. Study quality and transparency were assessed according to design, using thematic analysis for synthesis.

Results: Nine studies, selected from 7,607 records, encompassed three qualitative studies (semi-structured interviews), three RCTs, two narrative reviews and one survey study. The analysis identified five key themes: (1) Patients are willing to accept adverse events, like gastrointestinal disorders, for successful weight loss, (2) Patients experience improved physical functioning, well-being, and active daily living as a result of weight loss, (3) Patients express diverse opinions and skills regarding the medication's usability, (4) Patients believe that the medication improves their ability to manage sweet cravings, (5) Gender seems to affect patients' experiences with the medication, with females reporting more benefits than males.

Conclusion: Despite a huge demand and usage of GLP1-RAs, qualitative research on patients' experiences is scarce. Further studies are crucial for understanding short and long-term patient experiences.

背景:肥胖是一种复杂的疾病,也是公认的公共卫生挑战。先前的治疗方案与高失败率相关,但最近的试验表明,GLP1-RAs可以实现显著的体重减轻。然而,对于GLP1-RAs患者的经历知之甚少。目的:系统回顾GLP1-RAs治疗的相关研究。方法:在PubMed、PsycINFO、Embase和社会学文摘中检索文献,包括成人GLP1-RAs经历的研究,无论方法如何。研究排除:精神疾病,怀孕,前减肥手术,多囊卵巢综合征。根据设计评估研究质量和透明度,使用主题分析进行综合。结果:从7607份记录中选择了9项研究,包括3项定性研究(半结构化访谈)、3项随机对照试验、2项叙述性综述和1项调查研究。分析确定了五个关键主题:(1)为了成功减肥,患者愿意接受胃肠道疾病等不良事件;(2)减肥后,患者的身体功能、幸福感和日常生活都有所改善;(3)患者对药物的可用性表达了不同的意见和技能;(4)患者认为药物提高了他们控制甜食渴望的能力;(5)性别似乎影响了患者的用药体验。女性比男性受益更多。结论:尽管GLP1-RAs的需求量和使用量很大,但对患者体验的定性研究却很少。进一步的研究对于了解患者的短期和长期经历至关重要。
{"title":"Patients' experiences with GLP1-RAs - a systematic review.","authors":"Christoffer Kraul Ibsen, Marius Brostrøm Kousgaard, Sofie Olsen, Ann-Kathrin Lindahl Christiansen, Catharina Thiel Sandholdt, Rasmus Rørth, Gritt Overbeck","doi":"10.1080/02813432.2025.2477141","DOIUrl":"10.1080/02813432.2025.2477141","url":null,"abstract":"<p><strong>Background: </strong>Obesity is a complex condition and a recognized public health challenge. Previous treatment options were associated with high failure rates, but recent trials have shown that significant weight loss can be achieved with GLP1-RAs. However, little is known about the patient's experiences with GLP1-RAs.</p><p><strong>Objectives: </strong>This paper systematically reviews research on patients' experience with GLP1-RAs.</p><p><strong>Methods: </strong>A literature search in PubMed, PsycINFO, Embase and Sociological Abstracts included studies on adults' experiences with GLP1-RAs, regardless of methodology. Exclusions of studies: mental illness, pregnancy, former bariatric surgery, PCOS. Study quality and transparency were assessed according to design, using thematic analysis for synthesis.</p><p><strong>Results: </strong>Nine studies, selected from 7,607 records, encompassed three qualitative studies (semi-structured interviews), three RCTs, two narrative reviews and one survey study. The analysis identified five key themes: (1) Patients are willing to accept adverse events, like gastrointestinal disorders, for successful weight loss, (2) Patients experience improved physical functioning, well-being, and active daily living as a result of weight loss, (3) Patients express diverse opinions and skills regarding the medication's usability, (4) Patients believe that the medication improves their ability to manage sweet cravings, (5) Gender seems to affect patients' experiences with the medication, with females reporting more benefits than males.</p><p><strong>Conclusion: </strong>Despite a huge demand and usage of GLP1-RAs, qualitative research on patients' experiences is scarce. Further studies are crucial for understanding short and long-term patient experiences.</p>","PeriodicalId":21521,"journal":{"name":"Scandinavian Journal of Primary Health Care","volume":" ","pages":"370-379"},"PeriodicalIF":1.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12090293/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143606330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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Scandinavian Journal of Primary Health Care
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