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Effect of Coenzyme Q10 on DNA Fragmentation, Membrane Integrity, and Sperm Chromatin Condensation after Thawing of Frozen Semen 辅酶Q10对冷冻精液解冻后DNA断裂、膜完整性和精子染色质凝聚的影响
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.52547/sjku.26.7.34
M. Rezaie, M. Rezaie, B. Nikkhoo, A. Allahveisi, Daem Raoshani
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引用次数: 0
Effect of Troxerutin on Oxidative Stress Induced by Myocardial Ischemia / Reperfusion in Diabetic Rats 曲希鲁汀对糖尿病大鼠心肌缺血/再灌注氧化应激的影响
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.52547/sjku.26.7.11
H. Ahmadi, Homiera Hatami Nemati, R. Badalzadeh
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引用次数: 0
Sonography evaluation of gallbladder ejection fraction and volume in diabetic patients: a case control study 超声评估糖尿病患者胆囊射血分数和体积:一项病例对照研究
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.52547/sjku.26.7.53
H. Bashiri, Farshad Sheikhesmaili
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引用次数: 0
Rare Actinobacteria and Their Potential Biotechnological Applications 稀有放线菌及其潜在的生物技术应用
Q4 Medicine Pub Date : 2022-01-01 DOI: 10.52547/sjku.26.7.108
Hamid Abedinlou, Y. Bahrami, S. Mohammadi, Elham Kakaie
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引用次数: 5
Design of an Internationalization Model for Service Businesses in Border Areas in Medical Tourism 边境地区医疗旅游服务企业国际化模式设计
Q4 Medicine Pub Date : 2021-12-01 DOI: 10.52547/sjku.26.6.24
Anvar Ebrahimi, Ali Badi zadeh, kambiz Heidar Zadeh Hanazaei
Background and Aim: Development of medical tourism can contribute to employment boom in border areas. This study aimed to design an internationalization model for service businesses in border areas in relation to medical tourism industry. Materials and Methods: The current study was performed by using a sequential explanatory mixed method. In qualitative stage, to identify principal components for internationalization of service businesses in border areas considering medical tourism, literature review and in-depth interview were carried out and to finalize the components, Delphi method was used. In quantitative stage we used exploratory factor analysis to evaluate the extracted model. Using SPSS and Smart PLS software, we used qualitative content analysis and structural equations for data analysis. Results: For the identification of the principal components, a total of 20 in-depth interviews were performed and, for finalization of the model, 388 people were entered into the study. Seven dimensions as the model dimensions along with sub-components were extracted. The results showed that all the structural, behavioral and environmental factors were effective in the processes (amount: 0.83 and t: 45.12) and the results (amount: 0.75 and t: 10.34). Also all dimensional processes can affect the results (amount: 0.87 and t: 12.67). It can be concluded that casual accuracy relationships existing in the studied model are confirmed and it is a suitable model. Conclusion: All the structural, behavioral and environmental factors can affect the results and processes. Also all dimensional processes can affect the results. The above mentioned model was confirmed. Therefore, to internationalize medical tourism, at first, the current status of the country’s border areas should be compared to that of the model. In order to move forward for internationalization, necessary actions based on a multi-year plan should be considered.
背景与目的:发展医疗旅游可以促进边境地区的就业繁荣。本研究旨在设计边境地区医疗旅游服务业的国际化模式。材料与方法:本研究采用顺序解释混合法。在定性阶段,通过文献回顾和深度访谈来确定边境地区医疗旅游服务企业国际化的主成分,并采用德尔菲法最终确定成分。定量阶段采用探索性因子分析对提取的模型进行评价。运用SPSS和Smart PLS软件,采用定性内容分析和结构方程对数据进行分析。结果:为了确定主成分,共进行了20次深度访谈,为了最终确定模型,共有388人参与了研究。提取了7个维度及其子组件作为模型维度。结果表明,结构因素、行为因素和环境因素对过程(量:0.83,t: 45.12)和结果(量:0.75,t: 10.34)均有效。此外,所有维度过程都会影响结果(amount: 0.87, t: 12.67)。结果表明,模型中存在的随机精度关系得到了证实,是一种合适的模型。结论:结构因素、行为因素和环境因素均可影响结果和过程。此外,所有维度过程都会影响结果。上述模型得到了验证。因此,要实现医疗旅游国际化,首先要将国家边境地区的现状与模式进行比较。为了推进国际化,应该考虑以多年计划为基础的必要行动。
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引用次数: 0
Effect of Taping Therapy on Primary Dysmenorrhea Severity and Premenstrual Syndrome in University Students 贴敷治疗对大学生原发性痛经严重程度及经前综合征的影响
Q4 Medicine Pub Date : 2021-12-01 DOI: 10.52547/sjku.26.6.124
S. Rabiepour, Seyran Khezri
Background and Aim: The aim of this study was to determine the effect of taping therapy on primary dysmenorrhea severity, premenstrual syndrome and its dimensions in Sardasht University students from 2018 to 2019. Materials and Methods: In this experimental study 50 female students with moderate to severe dysmenorrhea and mild to moderate premenstrual syndrome were selected randomly and placed into control (n = 25) and intervention (n = 25) groups by blocking method. The intervention group used tape; the control group did not use anything but were attended in a free training class session. The questionnaires used in this study included demographic and menstrual characteristics questionnaire, visual analog scale questionnaire, premenstrual syndrome checklist and Moos menstrual distress questionnaire. Data obtained from these questionnaires were analyzed using descriptive statistics and independent t-test, paired t-test, chi-square test and ANCOVA. Results: There was no statistically significant difference between the two groups in regard to the demographic characteristics (P <0.05). The mean scores of dysmenorrhea, menstrual distress questionnaires and its dimensions except for arousal, were not significantly different between the intervention and control groups before the intervention (P <0.05). Also, there was no significant difference between the groups in relation to the total scores of dysmenorrhea, menstrual distress questionnaires and its dimensions, except for severity of dysmenorrhea after the intervention (P<0.05). Results of ANCOVA after controlling the confounding variables, showed only a significant difference between the control and intervention groups in regard to the severity of dysmenorrhea (P <0.05). Conclusion: The results of this study showed that taping therapy can be used as an effective non-pharmacological method in the treatment of dysmenorrhea.
背景与目的:本研究旨在探讨贴敷治疗对2018 - 2019年萨尔达什特大学学生原发性痛经严重程度、经前综合征及其维度的影响。材料与方法:本实验随机选取中重度痛经、轻中度经前综合征女生50例,采用阻断法分为对照组(n = 25)和干预组(n = 25)。干预组使用胶带;对照组没有使用任何东西,而是参加了一个免费的培训班。本研究采用的问卷包括人口统计学和月经特征问卷、视觉模拟量表、经前综合征检查表和Moos月经困扰问卷。对问卷数据进行描述性统计、独立t检验、配对t检验、卡方检验和方差分析。结果:两组患者人口学特征比较,差异无统计学意义(P <0.05)。干预前,干预组与对照组在痛经、月经困扰问卷及其各维度(觉醒项除外)的平均得分均无显著差异(P <0.05)。除干预后痛经严重程度外,两组间痛经总分、痛经困扰问卷及其维度差异均无统计学意义(P<0.05)。控制混杂变量后的ANCOVA结果显示,对照组与干预组在痛经严重程度上仅有显著差异(P <0.05)。结论:本研究结果表明,贴敷疗法可作为一种有效的非药物治疗痛经的方法。
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引用次数: 0
particle pollution inside and outside of Tohid Hospital in Sanandaj and modeling of dispersion using Surfer software Sanandaj Tohid医院内外的颗粒污染以及使用Surfer软件对扩散进行建模
Q4 Medicine Pub Date : 2021-12-01 DOI: 10.52547/sjku.26.6.11
Ameneh Yousefzadeا, Saeed Dehestani Athar, E. Darvishi, Manuchehr Ahmadi Hedayati, Rasool Nasiri Kalmarzi, A. Maleki
Background and Aim: People spent most of their time indoors. Therfore, quality of indoor air ,especially in the therapeutic settings is of particular importance. This study aimed to determine the level of pollutants in indoor and outdoor air of Tohid Hospital in Sanandaj. Materials and Methods: In this cross-sectional descriptive study 120 indoor and outdoor air samples were collected by TES-5200 copper counterpart machine made by TES company in Taiwan. Particulate matter samples were collected from 9 wards and also 3 stations in every ward in the hospital. Also air samples were obtained from 3 selected stations outside the hospital. Samples were taken from the selected sites twice. The results were analyzed by Excel and SPSS software. Results: According to the results of this study, the highest and lowest concentrations of particulate matter (PM2.5, PM4, PM7, PM10) belonged to the emergency room and the operating room, respectively. The highest level of PM1 concentration was detected in the ICU ward. There was no significant relationship between temperature and particle concentration and also between moisture and particle concentration in the wards of the hospital. In regard to particulate matter, the emergency department was the most contaminated ward and the operating room had the best condition. Conclusion: The relationship between the concentrations of particles in the outdoor and indoor air indicated the penetration of these particles from outside into the hospital building. Also, outdoor air can affect indoor air quality.
背景与目的:人们大部分时间都在室内度过。因此,室内空气质量,特别是在治疗环境中尤为重要。本研究旨在确定Sanandaj Tohid医院室内和室外空气中的污染物水平。材料与方法:本研究采用台湾TES公司生产的TES-5200型铜对应机采集120份室内外空气样本。在医院9个病区和每个病区3个监测站采集颗粒物样本。此外,还从医院外选定的3个站点采集了空气样本。从选定的地点抽取了两次样本。采用Excel和SPSS软件对结果进行分析。结果:根据本研究结果,PM2.5、PM4、PM7、PM10浓度最高和最低的分别属于急诊室和手术室。ICU病房PM1浓度最高。医院病房温度与颗粒浓度、湿度与颗粒浓度之间无显著关系。在颗粒物污染方面,急诊科是污染最严重的病房,手术室的污染状况最好。结论:室外和室内空气中颗粒浓度的关系表明这些颗粒从室外进入医院建筑。此外,室外空气也会影响室内空气质量。
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引用次数: 0
Role of Clinical Examination in the Diagnosis of Breast Cancer 临床检查在乳腺癌诊断中的作用
Q4 Medicine Pub Date : 2021-12-01 DOI: 10.52547/sjku.26.6.1
H. Moaiery, Mojgan Nabatzade, E. Akbari, Boshra Zareei, Aziz Rasouli
Background and Aim: Breast cancer is the most common malignancy among women in the world. Timely use of appropriate diagnostic methods in the early stages of this cancer can reduce its consequences and mortality. Materials and Methods: 287 women with breast mass referring to the Breast Cancer Research Center affiliated to Shahid Beheshti University of Medical Sciences, Tehran (Iran) participated in this cross-sectional study. Demographic data, clinical manifestations and drug history were recorded. Clinical examinations were carried out by a qualified physician. Finally, the correspondence between the data obtained from the clinical examinations with the pathologic results was evaluated. Results: 287 women with breast cancer (age range: 22-84 year old) participated in the study. Mean and standard deviation (SD) of participants’ age was 47.71±11.62. Based on pathology results 64 subjects (22.30%) had benign and 223 (77.70%) had malignant lesions. 37 subjects (12.89%) had benign and 250 (87.11%) had malignant lesions on the basis of the clinical breast examination (CBE). Sensitivity and specificity of CBE were 98.21% and 51.56%, and also, positive predictive value (PPV) and negative predictive value (NPV) were 87.6% and 89.19% respectively. Younger women were less likely to have malignant breast mass compared to older women. Moreover, a significant difference was found between unemployed and employed women as well as between menopausal and non-menopausal women. Conclusion: The results of the present study showed that clinical examination by skilled physicians can still be an important, highly sensitive and reliable method for diagnosis of breast cancer, especially in the patients who had breastfed their infants for more than 24 to 72 months, and menopausal women or patients with more than 3 pregnancies.
背景与目的:乳腺癌是世界上女性中最常见的恶性肿瘤。在这种癌症的早期阶段及时使用适当的诊断方法可以减少其后果和死亡率。材料和方法:287名来自德黑兰(伊朗)Shahid Beheshti医学科学大学附属乳腺癌研究中心的乳腺肿块患者参与了本横断面研究。记录患者的人口学资料、临床表现及用药史。临床检查由一位合格的医生进行。最后,评估临床检查数据与病理结果之间的对应关系。结果:287名乳腺癌女性(年龄范围:22-84岁)参与了这项研究。年龄的均值和标准差(SD)为47.71±11.62。病理结果显示良性64例(22.30%),恶性223例(77.70%)。临床乳腺检查(CBE)良性病变37例(12.89%),恶性病变250例(87.11%)。CBE的敏感性为98.21%,特异性为51.56%,阳性预测值(PPV)和阴性预测值(NPV)分别为87.6%和89.19%。与年长女性相比,年轻女性患恶性乳房肿块的可能性较小。此外,失业妇女和就业妇女以及更年期妇女和非更年期妇女之间也存在显著差异。结论:本研究结果表明,熟练医师的临床检查仍然是诊断乳腺癌的重要、高灵敏度和可靠的方法,特别是对母乳喂养婴儿超过24 ~ 72个月的患者,以及绝经期妇女或怀孕3次以上的患者。
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引用次数: 0
Production of Egg Yolk Immunoglobulin (IgY) Against Recombinant LTB of Enterotoxigenic Escherichia coli (ETEC) and Evaluation of Its Protective Effect in Animal Model 抗肠产毒素大肠杆菌(ETEC)重组LTB的卵黄免疫球蛋白(IgY)的制备及其动物模型保护作用评价
Q4 Medicine Pub Date : 2021-12-01 DOI: 10.52547/sjku.26.6.107
Maryam Mafi, latif Mousavi gargari, S. Nazarian, fatemeh mohammad khani
Background and Aim: Enterotoxigenic Escherichia coli is one of the most common bacterial causes of diarrhea worldwide. One of the most important ETEC colonization factors is B subunit of the heat labile enterotoxin, which forms the connecting part of the toxin. In the present study, egg yolk immunoglobulin (IgY) against recombinant LTB protein was produced and its protective effect was evalutated in the animal model. Material and methods: Hens were injected intramuscularly with 100 μg of recombinant LTB protein. Antibody titers of the sera were estimated and the eggs were collected. IgYs were purified from egg yolk and the antibody titers were subsequently estimated by ELISA method. Effecacy of different concentrations of IgY against the effect of LT toxin on Y1 cells was also studied. In order to investigate the effect of IgY-treated bacteria on intestinal epithelial cells we used standard Ileal loop technique. Results: Induction of protein expression led to the production of recombinant LTB with molecular weight of about 14 kDa. Concentration of purified protein was 4.5mg/ml. Immunization of the hens induced serum antibody rise. IgY against LTB was purified from egg yolk at a concentration of 12mg/ml. 125 μg per ml of IgY against LTB prevented the effects of heat labile enterotoxin on Y1. In the Ileal loop test, 1.5 mg / ml of IgY neutralized the toxin effect of LTB on the intestine. Accumulation of fluid in the test loops decreased by 74.8% compared to that in the untreated control loops. Conclusion: The results obtained indicated that specific egg yolk immunoglobulin was effective against recombinant LTB protein and can be used as a preventive antibody to inhibit the heat labile enterotoxin function of ETEC bacteria.
背景与目的:产肠毒素大肠杆菌是世界范围内引起腹泻的最常见细菌之一。ETEC最重要的定殖因子之一是热不稳定肠毒素的B亚基,它构成了毒素的连接部分。本研究制备了抗重组LTB蛋白的卵黄免疫球蛋白(IgY),并在动物模型上评价了其保护作用。材料与方法:将重组LTB蛋白100 μg肌肉注射给鸡。测定血清抗体滴度,采集虫卵。从蛋黄中纯化IgYs,用ELISA法测定抗体滴度。研究了不同浓度IgY对LT毒素对Y1细胞的影响。为了研究igy处理的细菌对肠上皮细胞的影响,我们采用标准回肠环技术。结果:通过诱导蛋白表达,获得分子量约为14 kDa的重组LTB。纯化蛋白浓度为4.5mg/ml。免疫后蛋鸡血清抗体升高。从蛋黄中纯化抗LTB IgY,浓度为12mg/ml。125 μg / ml IgY抗LTB可抑制热不稳定肠毒素对Y1的影响。回肠环试验中,1.5 mg / ml IgY可中和LTB对肠道的毒素作用。与未经处理的控制回路相比,测试回路中的液体积聚减少了74.8%。结论:卵黄特异性免疫球蛋白对重组LTB蛋白有抑制作用,可作为抑制ETEC菌热不稳定肠毒素功能的预防性抗体。
{"title":"Production of Egg Yolk Immunoglobulin (IgY) Against Recombinant LTB of Enterotoxigenic Escherichia coli (ETEC) and Evaluation of Its Protective Effect in Animal Model","authors":"Maryam Mafi, latif Mousavi gargari, S. Nazarian, fatemeh mohammad khani","doi":"10.52547/sjku.26.6.107","DOIUrl":"https://doi.org/10.52547/sjku.26.6.107","url":null,"abstract":"Background and Aim: Enterotoxigenic Escherichia coli is one of the most common bacterial causes of diarrhea worldwide. One of the most important ETEC colonization factors is B subunit of the heat labile enterotoxin, which forms the connecting part of the toxin. In the present study, egg yolk immunoglobulin (IgY) against recombinant LTB protein was produced and its protective effect was evalutated in the animal model. Material and methods: Hens were injected intramuscularly with 100 μg of recombinant LTB protein. Antibody titers of the sera were estimated and the eggs were collected. IgYs were purified from egg yolk and the antibody titers were subsequently estimated by ELISA method. Effecacy of different concentrations of IgY against the effect of LT toxin on Y1 cells was also studied. In order to investigate the effect of IgY-treated bacteria on intestinal epithelial cells we used standard Ileal loop technique. Results: Induction of protein expression led to the production of recombinant LTB with molecular weight of about 14 kDa. Concentration of purified protein was 4.5mg/ml. Immunization of the hens induced serum antibody rise. IgY against LTB was purified from egg yolk at a concentration of 12mg/ml. 125 μg per ml of IgY against LTB prevented the effects of heat labile enterotoxin on Y1. In the Ileal loop test, 1.5 mg / ml of IgY neutralized the toxin effect of LTB on the intestine. Accumulation of fluid in the test loops decreased by 74.8% compared to that in the untreated control loops. Conclusion: The results obtained indicated that specific egg yolk immunoglobulin was effective against recombinant LTB protein and can be used as a preventive antibody to inhibit the heat labile enterotoxin function of ETEC bacteria.","PeriodicalId":21808,"journal":{"name":"Scientific Journal of Kurdistan University of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90533726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Futurology of universal health coverage in Iran: A letter to the editor 伊朗全民健康覆盖的未来学:致编辑的一封信
Q4 Medicine Pub Date : 2021-12-01 DOI: 10.52547/sjku.26.6.139
علی محمد مصدق راد, مهدیه حیدری
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引用次数: 0
期刊
Scientific Journal of Kurdistan University of Medical Sciences
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