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Microsurgery for anterior communicating artery aneurysms: One size does not fit all 前交通动脉瘤的显微外科治疗:一种方法不适合所有
Pub Date : 2022-01-01 DOI: 10.4103/jcvs.jcvs_22_22
Adesh Shrivastava, S. Nair, Rakesh Mishra
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引用次数: 0
Indocyanine green fluorescence video angiography – An indispensable tool for avoiding vascular complications during microsurgical clipping of ruptured intracranial aneurysms and improving surgical outcome: A preliminary study 吲哚菁绿荧光视频血管造影——显微手术切除颅内动脉瘤破裂时避免血管并发症和改善手术效果不可缺少的工具:初步研究
Pub Date : 2022-01-01 DOI: 10.4103/jcvs.jcvs_14_22
A. Acharya, Sarvpreet Singh Grewal
Background: The surgical complications in aneurysmal microsurgical clipping are attributable primarily to vascular compromise and retraction injury. The vascular complications almost 50% of these. ICG-VA gives us intraoperative real-time high definition functional imaging of the cerebrovascular tree, thereby allowing immediate quality assessment and control of aneurysm obliteration and parent vessel optimisation. Here we report our preliminary data of an ongoing series of patient study. Objective: This study aims at evaluating the role of ICG VA in avoiding vascular complications during microsurgical clipping of ruptured intracranial aneurysms and ascertaining normative data for ICG dye administration. Materials and Methods: The study aimed at determining the utility of microscope incorporated (Leica M530 OHX microscope) ICG VA in ruptured aneurysm surgery. We used ICG-VA in 17 patients of ruptured aneurysm with WFNS grade 1 and 2 as an adjunct to surgery. We studied multiple patient characteristics, intraoperative ICG peak flow and washout time of dye, and changes made in the operative decisions, and outcome of the surgeries. Results: ICG-VA helped in intraoperative decision making for 5 out of 17 patients. In one patient, inadequate clipping with residual neck was confirmed with ICG-VA and the clip was adjusted. In three patient's perforator/additional vessel compromise was found hence needed clip readjustment, whereas in two patients ICG-VA demonstrated residual filling of large neck sac and 2nd clip was applied in tandem. Conclusion: ICG VA is a conclusively simple adjunctive tool for the early detection and prevention of vascular compromise of multiple vessels and perforators during ruptured aneurysm surgery.
背景:显微手术夹闭动脉瘤的手术并发症主要是由于血管妥协和回缩损伤。其中血管并发症几乎占50%。ICG-VA为我们提供术中实时高清晰度脑血管树功能成像,从而可以立即进行质量评估和控制动脉瘤闭塞和母血管优化。在此,我们报告正在进行的一系列患者研究的初步数据。目的:本研究旨在评价ICG VA在颅内动脉瘤破裂显微手术夹闭中避免血管并发症的作用,并确定ICG染色给药的规范性数据。材料与方法:本研究旨在确定显微结合(徕卡M530 OHX显微镜)ICG VA在动脉瘤破裂手术中的应用价值。我们对17例WFNS为1级和2级的破裂动脉瘤患者采用ICG-VA作为辅助手术。我们研究了患者的多种特征,术中ICG峰值流量和染料冲洗时间,以及手术决策的变化和手术结果。结果:在17例患者中,有5例患者有ICG-VA辅助术中决策。在1例患者中,ICG-VA证实夹片不充分,颈部残留,并调整夹片。在3例患者中发现穿支/附加血管受损,因此需要重新调整夹子,而在2例患者中,ICG-VA显示大颈囊残留充盈,第2个夹子串联应用。结论:ICG VA是动脉瘤破裂手术中早期发现和预防多支血管及穿支血管受损的一种简单的辅助工具。
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引用次数: 1
Syndromic association of spinal arteriovenous malformations: CLOVES syndrome 脊髓动静脉畸形的综合征相关性:CLOVES综合征
Pub Date : 2022-01-01 DOI: 10.4103/jcvs.jcvs_21_22
M. Mahajan, Daljit Singh, H. Sahni, Sumit Bhandari, D. Vishwakarma
The study design was a case report of spinal cord arteriovenous malformation (SCAVM) with various associations. The objective of this study was to demonstrate the need to identify atypical clinical associations with spinal arteriovenous malformation and their staged management. A 19-year-old boy was diagnosed with SCAVM after paraplegia and bowel bladder disturbances. However, a complete diagnosis of SCAVM with its syndromic association helps to treat the patient in holistic way. The correct diagnosis of SCAVMs and their type is difficult. Complete diagnosis relies on radiological investigations as well as detailed examination. The early and complete diagnoses of SCAVMs are important because patients are likely to have better functional statuses after treatment if their pre-treatment deficits are relatively mild.
本研究设计是一份脊髓动静脉畸形(SCAVM)的病例报告。本研究的目的是证明需要识别非典型临床关联与脊柱动静脉畸形及其分阶段处理。一名19岁的男孩在截瘫和膀胱紊乱后被诊断为SCAVM。然而,对SCAVM及其综合征相关性的完整诊断有助于对患者进行整体治疗。scavm及其类型的正确诊断是困难的。完整的诊断依赖于放射学检查和详细的检查。scavm的早期和完整诊断是很重要的,因为如果患者治疗前的缺陷相对轻微,治疗后可能具有更好的功能状态。
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引用次数: 0
Optico-chiasmatic hypothalamic cavernomas - A report of three cases and review of literature 视交叉下丘脑海绵状瘤:附3例报告及文献复习
Pub Date : 2021-07-01 DOI: 10.4103/jcvs.jcvs_8_22
Roopesh Kumar, A. Karthikayan, Adhithyan Rajendran
Optochiasmatic hypothalamic cavernous malformations (CMs) are exceedingly rare lesions and can manifest with visual deficits of varying magnitudes. They also can result in sudden-onset visual loss due to apoplexy. Magnetic resonance imaging can delineate the lesions and differentiate it from other common lesions like glioma or craniopharyngioma. Preoperative visual assessment including perimetry and optical coherence tomogram has to be performed whenever possible to assess the degree of deficits and also for prognostication. Microsurgical excision improves the visual deficits in majority of instances as documented by earlier reports and has to be undertaken as an emergency in apoplexy. Various corridors can be used to reach the lesion including anterolateral, midline transbasal anterior interhemispheric approach, and transnasal endoscopic approaches. The aim should be to achieve a gross total excision with minimal manipulation of surrounding white matter tracts to improve the visual outcome. There is a limited role for stereotactic radiosurgery. In the present study, we report three cases of CMs involving optic chiasm and hypothalamus including a case of apoplexy managed by gross total microsurgical resection with good outcome and also review the relevant literature on the natural history and management strategies
视交叉下丘脑海绵状血管瘤是一种非常罕见的病变,可表现为不同程度的视觉缺陷。它们还可能导致中风引起的突发性视力丧失。磁共振成像可以描绘病变并将其与其他常见病变如胶质瘤或颅咽管瘤区分开来。术前视力评估,包括眼周检查和光学相干断层扫描,必须尽可能进行评估缺损程度和预测。显微外科手术切除在大多数情况下改善了早期报告所记载的视力缺陷,必须作为中风的紧急情况进行。可采用多种通道到达病灶,包括前外侧、中线经基底前半球间入路和经鼻内镜入路。目的是在对周围白质束进行最小操作的情况下实现总切除,以改善视觉效果。立体定向放射手术的作用有限。在本研究中,我们报告了3例涉及视交叉和下丘脑的CMs,其中包括1例中风患者,经显微外科手术切除,结果良好,并回顾了有关自然病史和治疗策略的相关文献
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引用次数: 1
Microsurgery of complex intracranial aneurysms 复杂颅内动脉瘤的显微外科治疗
Pub Date : 2021-07-01 DOI: 10.4103/jcvs.jcvs_6_22
B. Misra, Harshad R Purandare
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引用次数: 0
Outcome of microsurgical clipping of anterior communicating aneurysms: A single-centre experience 显微外科夹闭前交通动脉瘤的疗效:单中心经验
Pub Date : 2021-07-01 DOI: 10.4103/jcvs.jcvs_10_22
M. N. Kumar, R. Prasad, Senthil Kumar, A. Pravallika
Anterior communicating (ACOM) aneurysms are the most common intracranial aneurysms. About 30%–40% of ruptured intracranial aneurysms are ACOM aneurysms. Its complex structural and anatomical variability and its critical location pose a great challenge to the surgeon during microsurgical clipping. We share our experience in clipping these aneurysms and its outcome. The aim was to study the outcome following microsurgical clipping of ACOM artery aneurysm presenting with rupture and subarachnoid haemorrhage and to determine the factors which dictate the clinical outcome after 6 months. The study includes all cases of ruptured ACOM aneurysms who underwent microsurgical clipping between the period of 2016 and 2020. The medical records were analysed retrospectively and results were recorded. The study shows that the outcome of the patients depends on presenting World Federation of Neurological Surgeons grade, anterosuperiorly projecting aneurysms are at high risk for intraoperative rupture and complications such as lacunar infarcts are common with the usage of temporary clips.
前交通动脉瘤是最常见的颅内动脉瘤。约30%-40%的破裂颅内动脉瘤为ACOM动脉瘤。其复杂的结构和解剖变异性以及关键的位置对外科医生在显微手术中进行夹夹提出了很大的挑战。我们分享我们的经验,夹这些动脉瘤和它的结果。目的是研究显微手术夹闭出现破裂和蛛网膜下腔出血的ACOM动脉瘤后的结果,并确定决定6个月后临床结果的因素。该研究包括2016年至2020年期间接受显微手术切除的所有ACOM动脉瘤破裂病例。回顾性分析病历并记录结果。研究表明,患者的预后取决于世界神经外科医师联合会的分级,上向前突出的动脉瘤术中破裂的风险很高,使用临时夹夹时腔隙性梗死等并发症很常见。
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引用次数: 0
Do intra operative brain conditions during clipping for ruptured intra cranial aneurysms affect the outcome? Being devil's advocate 颅内动脉瘤破裂夹闭术中脑内状况是否影响预后?唱反调
Pub Date : 2021-07-01 DOI: 10.4103/jcvs.jcvs_11_22
Navneet Singla, K. Reddy, A. Aggarwal, R. Chhabra, H. Bhagat
Introduction: For a disease like aneurysmal subarachnoid haemorrhage (aSAH) which continues to have high morbidity and mortality, prognostication is imperative. This gives realistic goals to both the health-care worker and the patient. Unfavourable brain conditions during surgery like dural bulge, brain swelling, petechial haemorrhages, need for ventricular tap are conventionally thought to be harbingers of poor outcomes. But is it really so? Methods: Fifty-four consecutively operated patients of aSAH were studied. Clinical grade at admission (H and H, World Federation of Neurosurgical Societies (WFNS)), Dural bulge, brain swelling, petechial haemorrhages, need for ventricular tap, and brain pulsatility were studied for outcome parameters like Glasgow outcome scale (GOS) at 1 and 3 months and development of focal deficits. Results: H and H and WFNS grades had a significant correlation with GOS. We found that the need for augmentation duraplasty had a significant association with the outcome and appearance of focal deficits. However, unfavourable brain conditions like--dural bulge, brain swelling, petechial haemorrhages, need for ventricular tap, absence of brain pulsatility during surgery did not have a significant impact on the outcome. Conclusions: Clinical grading by far remains the best predictor of outcome. Intra-operative brain conditions did not have a bearing on the outcome. The mechanism by which poor grade patients exhibit poor outcomes remains elusive. At least in the present study, it was not by way of manifesting as unfavourable brain conditions. A word of caution--further large studies are required before definite conclusions can be drawn.
对于像动脉瘤性蛛网膜下腔出血(aSAH)这样的疾病,其发病率和死亡率仍然很高,预后是必要的。这给保健工作者和病人都提供了现实的目标。手术中不利的脑部状况,如硬脑膜膨出、脑肿胀、点状出血、需要心室穿刺等,通常被认为是不良结果的先兆。但真的是这样吗?方法:对54例连续手术的aSAH患者进行分析。入院时的临床分级(H和H级,世界神经外科学会联合会(WFNS))、硬脑膜膨出、脑肿胀、点状出血、需要心室穿刺和脑脉搏等结果参数,如1个月和3个月的格拉斯哥结果量表(GOS)和局灶性缺陷的发展。结果:H、H、WFNS评分与GOS有显著相关性。我们发现硬脑膜成形术的需要与局灶性缺陷的结果和外观有显著的关联。然而,诸如硬脑膜膨出、脑肿胀、点状出血、需要心室穿刺、手术中没有脑搏动等不利的脑部状况对结果没有显著影响。结论:到目前为止,临床分级仍然是预后的最佳预测指标。术中脑部状况对结果没有影响。低度评分患者表现出不良预后的机制仍然难以捉摸。至少在目前的研究中,它并没有表现为对大脑不利的状况。需要提醒的是,在得出明确的结论之前,还需要进一步的大规模研究。
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引用次数: 0
Statistical corner: Building own functions in R 统计角:在R中构建自己的函数
Pub Date : 2021-07-01 DOI: 10.4103/jcvs.jcvs_22_21
Mikko J. Pyysalo
Introduction: R is a programming language that can be used to efficiently solve statistical problems. Objectives: To demonstrate the method of building functions using R in statistical analysis and storing it for future use. Materials and Methods: A real world example of comparison of statistical values in aneurysm research with respect to its locations has been used to demonstrate how one might build a function using R. Results: Accurate results could be obtained and the function can be stored for later use. Conclusions: As the statistical tools required in research are recurrent, building functions in R and storing them for future use is highly recommended.
R是一种编程语言,可以用来有效地解决统计问题。目的:演示在统计分析中使用R构建函数并将其存储以备将来使用的方法。材料和方法:在动脉瘤研究中,一个关于动脉瘤位置的统计值比较的真实例子已经被用来演示如何使用r来建立一个函数。结果:可以获得准确的结果,并且该函数可以被存储以供以后使用。结论:由于研究中需要的统计工具是循环使用的,因此强烈建议在R中构建函数并将其存储以备将来使用。
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引用次数: 0
Thrombolysis beyond the time window in takayasu's arteritis: A challenging experience 在takayasu动脉炎的时间窗之外的溶栓:一个具有挑战性的经验
Pub Date : 2021-07-01 DOI: 10.4103/jcvs.jcvs_20_21
Madhavi Karri, Balakrishnan Ramasamy, E. Swamiappan, S. Perumal, K. Kannan
Takayasu's arteritis (TA) is chronic inflammatory vasculopathy preferentially affecting the aorta and its major branches. It is one of the potential causes of stroke in young adults. Here, we report a young female who presented to us with an acute-onset right hemiparesis with motor aphasia after 10 h of symptoms onset. Her National Institute of Health Stroke Scale (NIHSS) score at admission was 12. The stroke imaging showed acute infarct in the left middle cerebral artery territory with arterial spin labelling perfusion sequence showing diffusion perfusion mismatch with good penumbra. She underwent intravenous thrombolysis with tenecteplase, based on imaging findings and despite being out of window period. She had an excellent clinical recovery and was discharged with oral anticoagulant and azathioprine. After 3 months of stroke and recovery, follow-up was unremarkable with minimal residual deficits with an NIHSS score of 4 and Modified Rankin Scale of 1. Hence, appropriate early interventions in acute stroke in TA individuals are highly beneficial and timely considered for a good outcome and better quality of life.
高松动脉炎(Takayasu’s arteritis, TA)是一种慢性炎症性血管病变,主要累及主动脉及其主要分支。它是年轻人中风的潜在原因之一。在这里,我们报告了一位年轻女性,她在症状出现10小时后向我们提出了急性发作的右半瘫并运动失语。入院时,她的美国国立卫生研究院卒中量表(NIHSS)得分为12分。脑卒中成像显示左大脑中动脉急性梗死,动脉自旋标记灌注序列显示扩散灌注失配,半暗区良好。尽管处于窗期,但根据影像学表现,她接受了静脉溶栓治疗。患者临床恢复良好,出院时口服抗凝剂和硫唑嘌呤。脑卒中恢复3个月后,随访效果不显著,NIHSS评分为4分,修正Rankin量表为1分,剩余缺陷最小。因此,对TA患者的急性卒中进行适当的早期干预是非常有益和及时的,可以获得良好的预后和更好的生活质量。
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引用次数: 0
Post-Operative ischaemic stroke as a sequelae of unnoticed small internal carotid artery intimal flap 术后缺血性卒中作为未被注意的颈内动脉小内膜瓣的后遗症
Pub Date : 2021-07-01 DOI: 10.4103/jcvs.jcvs_5_22
Amit Sharma, A. Jagetia, A. Srivastava, Daljit Singh
The risk of stroke associated with aneurysm coiling can occur as a result of thromboembolic complications. The iatrogenic internal carotid artery (ICA) dissection can also lead to ischemic stroke. A 42-year-old patient was diagnosed with a left ICA paraclinoid aneurysm. The endovascular coil embolisation was done. The aneurysm was completely obliterated with preservation of parent artery and distal flow. In the post-operative period, the patient developed a left middle cerebral artery territory infarct. The patient underwent decompressive hemicraniectomy and check data structures and algorithms (DSA) showed ICA dissection with no distal flow. The retrospective examination of earlier DSA revealed a suspected small intimal flap which later progressed to complete dissection and resulted in the infarct. We are reporting this case intending to emphasize careful examination of angiogram and findings suggestive of even a small intimal flap of ICA must not be overlooked. It might progress to frank dissection, stenosis of ICA and even fatal ischaemic stroke.
由于血栓栓塞并发症,与动脉瘤缠绕相关的中风风险可能发生。医源性颈内动脉(ICA)剥离也可导致缺血性中风。一个42岁的病人被诊断为左ICA线旁动脉瘤。行血管内线圈栓塞术。动脉瘤被完全切除,保留了载动脉和远端血流。术后患者出现左侧大脑中动脉区域梗死。患者行半颅骨减压切除术并检查数据结构和算法(DSA)显示ICA夹层,无远端血流。早期DSA的回顾性检查显示一个可疑的小内膜皮瓣,后来发展为完全剥离并导致梗死。我们报告这个病例的目的是强调仔细的血管造影检查,即使是一个小的ICA内膜瓣的发现也不能忽视。它可能发展为明显的夹层,内腔动脉狭窄,甚至致命的缺血性中风。
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引用次数: 0
期刊
Journal of Cerebrovascular Sciences
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