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The association of bacterial infection with intracranial aneurysm disease 细菌感染与颅内动脉瘤疾病的关系
Pub Date : 2020-01-01 DOI: 10.4103/jcvs.jcvs_20_20
Mikko J. Pyysalo, T. Pessi, Joona Hallikainen, J. Frösen
The human body abounds in micro-organisms that maintain the vital balance of the internal ecosystem. Though it is well known that several benefit the human body while others are linked to disease, how the microbiota affects the pathology of intra-cranial aneurysms is an interesting arena that still requires exploration. Studies have suggested possible association between the excess of bacteria, such as those causing gingivitis, as well the deficit of bacteria, such as loss of gut flora due to antibiotics, to intracranial aneurysms and their subsequent behavior. The authors review existing literature on the subject and outline the scope for further research on the subject.
人体内有大量的微生物,它们维持着体内生态系统的重要平衡。虽然众所周知,有几种对人体有益,而另一些则与疾病有关,但微生物群如何影响颅内动脉瘤的病理是一个有趣的领域,仍需要探索。研究表明,细菌过量(如引起牙龈炎的细菌)和细菌不足(如抗生素导致的肠道菌群损失)与颅内动脉瘤及其后续行为之间可能存在关联。作者回顾了有关该主题的现有文献,并概述了该主题进一步研究的范围。
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引用次数: 0
A giant anterior inferior cerebellar artery aneurysm in the guise of a cerebellopontine angle tumour: A case report and review of literature 以桥小脑角肿瘤为伪装的巨大小脑前下动脉瘤一例报告及文献复习
Pub Date : 2020-01-01 DOI: 10.4103/jcvs.jcvs_3_20
Sumeet Narang, G. Manoharan, J. Dil, A. Raja
Giant intracranial aneurysms, and aneurysms in the posterior circulation of the brain, are each rare entity when considered separately. It is more uncommon to find both coexisting. Aneurysms usually present when they rupture and haemorrhage, and for one to present with non-haemorrhagic symptoms, is rarer. The authors present an unusual case of a giant aneurysm of the anterior inferior cerebellar artery masquerading as a cerebellopontine angle tumour with cerebellar signs. The patient was treated with a retromastoid suboccipital craniectomy and microsurgical clipping and excision, with excellent results. A PubMed search of existing literature was carried out and reviewed and has been discussed.
颅内巨动脉瘤和脑后循环动脉瘤,分别考虑时都是罕见的。两者共存的情况更为罕见。动脉瘤通常在破裂和出血时出现,而对于一个出现非出血症状的人来说,是罕见的。作者提出一个不寻常的情况下,巨大的动脉瘤小脑前下动脉伪装为小脑桥脑角肿瘤小脑体征。患者接受乳突后枕下颅骨切除术和显微外科夹持切除,效果良好。对现有文献进行了PubMed检索,并进行了审查和讨论。
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引用次数: 0
Long-term follow-up of large and giant intracranial aneurysms managed by endovascular techniques: Experience from a tertiary care neurosurgery institute in India 血管内技术治疗颅内大动脉瘤的长期随访:来自印度一家三级护理神经外科研究所的经验
Pub Date : 2020-01-01 DOI: 10.4103/jcvs.jcvs_18_20
Gautam Dutta, D. Mahajan, Daljit Singh, A. Jagetia, Hukum Singh, A. Srivastava
Introduction: We present our experience of managing large and giant intracranial aneurysms by conventional endovascular techniques. We discuss the long-term clinical and angiographic outcome of coiling of these aneurysms. Materials and Methods: We assessed a prospectively maintained database of patients with large and giant intracranial aneurysms managed by the endovascular techniques from January 2010 to December 2014. In 412 patients with 468 aneurysms managed during this period, 58 patients with 60 aneurysms were identified as either large or giant. Each patient's records were reviewed with regard to size, location and morphology of the aneurysms, Hunt and Hess grade, occlusion and coiling/recoiling rates. Clinical outcome was assessed using the modified Rankin Scale (mRS) score with score of 0–2 and 3–6 taken as favourable and unfavourable outcome, respectively. Results: Overall complication rate was 13.8%, and no intraprocedural death was seen. Angiographic and clinical follow-up was available for 49 patients with 49 aneurysms at an average of 28.7 months. Recanalisation rate was 26.5% in this study and of them 38.5% required retreatment. Favourable mRS score (0–2) was seen in 82.6% of ruptured aneurysms and 92.3% in unruptured aneurysms. Conclusion: Coiling of large and giant aneurysms is a safe and viable option with a very good clinical outcome in the long run. However, long-term clinical and angiographic follow-up is necessary as angiographic results immediately after the procedure may be deceptive.
简介:我们介绍了常规血管内技术治疗颅内大动脉瘤的经验。我们讨论这些动脉瘤卷曲的长期临床和血管造影结果。材料和方法:我们对2010年1月至2014年12月采用血管内技术治疗的颅内大动脉瘤患者的前瞻性数据库进行了评估。在这段时间内,412名患者的468个动脉瘤中,58名患者的60个动脉瘤被确定为大或巨。回顾每位患者的记录,包括动脉瘤的大小、位置和形态、Hunt和Hess分级、闭塞和卷曲/后坐率。临床结果采用改良Rankin量表(mRS)评分,0-2分为有利结果,3-6分为不利结果。结果:总并发症发生率为13.8%,无术中死亡病例。49例动脉瘤患者49个,平均随访28.7个月。本研究再通率为26.5%,其中38.5%需要再治疗。82.6%的破裂动脉瘤和92.3%的未破裂动脉瘤的mRS评分为0-2分。结论:大、巨动脉瘤卷取术是一种安全可行的治疗方法,长期疗效良好。然而,长期的临床和血管造影随访是必要的,因为手术后立即的血管造影结果可能具有欺骗性。
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引用次数: 0
Management strategies for cerebral arteriovenous malformation - An institutional experience 脑动静脉畸形的管理策略-一个机构经验
Pub Date : 2020-01-01 DOI: 10.4103/jcvs.jcvs_6_20
K. Sudhakar, A. Cheikh, Y. Yamada, Takao Teranishi, T. Kawase, Y. Kato
Background: Cerebral Arteriovenous Malformation represent a particularly challenging subset of lesions, given their overall low incidence and the high frequency with which some form of multimodality monitoring may be required for complete obliteration. Materials and Methods: We report retrospective analysis of 9 cases with unruptured cerebral arteriovenous malformation who got admitted in the Banbuntane Hotokokai Hospital, Fujita Health University, and Nagoya, Japan .from the year 2014 to 2017.surgical treatment was appropriate craniotomy and resection based on the location of the arteriovenous malformation with multimodality monitoring with Dual Image Video Angiography, Motor Evoked Potential, and FLOW 800. We studied the following factors: Sex, Age, Arteriovenous Malformation size, Location, occurrence of Intracranial Hemorrhage, Seizure type, Duration of Seizure history, Treatment modality, and Arteriovenous Malformation obliteration. We tested for statistical associations between these factors and seizure presentation and outcomes with Clinical follow-up. Outcome was compared with modified Rankin Scale Results: Out of 9 cases operated for intracranial arteriovenous malformation 5 patients were female and 4 were male. Age [ Mean 39.4 + 16.7] of the patients ranged from 20 to 66 , 5 patients were 25 - 40 and 2 were > 65 and < 25 each.6 patients were Spetzler - Martin Grade 2 ,1 patient was Spetzler - Martin Grade 4,Grade 3 and Grade 5. 3 patients were draining into superficial venous system and 2 patient were asymptomatic and incidentally diagnosed during screening procedure. There is no Mortality in this study.1 patient underwent Gamma Knife stereotactic radiosurgery. Conclusion: The increasing use of advance imaging techniques will increase the incidence of asymptomatic arteriovenous malformations. Non-ruptured arteriovenous malformation Spetzler Martin Grade 1 or Spetzler Martin Grade 2 have a good outcome for microsurgery [modified Rankin Scale and complete obliteration and there is better outcome with microsurgery.
背景:脑动静脉畸形是一种特别具有挑战性的病变子集,因为其总体发病率低,频率高,可能需要某种形式的多模式监测才能完全消除。材料与方法:回顾性分析2014年至2017年在日本名古屋的日本藤田卫生大学Banbuntane Hotokokai医院住院的9例未破裂的脑动静脉畸形。手术治疗是根据动静脉畸形的位置,在双像视频血管造影、运动诱发电位和FLOW 800多模态监测下进行适当的开颅和切除。我们研究了以下因素:性别,年龄,动静脉畸形大小,位置,颅内出血的发生,癫痫发作类型,癫痫发作史持续时间,治疗方式,动静脉畸形闭塞。我们通过临床随访检验了这些因素与癫痫发作表现和结果之间的统计学关联。结果:9例颅内动静脉畸形手术中,女性5例,男性4例。年龄[平均39.4 + 16.7],20 ~ 66岁,25 ~ 40岁5例,> 65、< 25岁各2例。6例患者为Spetzler - Martin 2级,1例为Spetzler - Martin 4级、3级和5级。3例患者进入浅静脉系统引流,2例无症状,在筛查过程中偶然发现。在这项研究中没有死亡率。1例患者行伽玛刀立体定向放射手术。结论:先进影像学技术的应用将增加无症状动静脉畸形的发生率。非破裂型动静脉畸形(Spetzler Martin Grade 1或Spetzler Martin Grade 2)显微手术(改良Rankin评分法和完全闭塞法)预后良好,显微手术预后更好。
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引用次数: 0
Musings about surgery for intra-cranial arterio-venous malformations 颅内动静脉畸形手术治疗的思考
Pub Date : 2020-01-01 DOI: 10.4103/jcvs.jcvs_15_20
A. Raja
Introduction: Neurosurgery has evolved with the times and as with all things with a rich history, there is much to be learnt from experience and much to be re-iterated in the present. Aims and objectives: To reinforce the key basic points in AVM surgery, for the benefit of all neurosurgeons operating on AVMs. Materials: Based on personal experience from over he author recollects integral points and principles of the surgical management of intra-cranial arterio-venous malformations (AVMs), highlighting the basic elements such as planning, exposure, equipment use, intra-operative identification, and safe approach, execution and hemostasis. Conclusion: The success of AVM surgery depends highly on methodical planning and precise execution.
导言:神经外科随着时代的发展而发展,就像所有具有丰富历史的事物一样,有很多东西需要从经验中学习,也有很多东西需要在现在重新迭代。目的和目的:强化动静脉畸形手术的关键基本点,为所有动静脉畸形手术的神经外科医生提供参考。资料:作者根据多年的个人经验,总结了颅内动静脉畸形(AVMs)手术治疗的要点和原则,强调了手术计划、手术暴露、设备使用、术中识别、安全入路、执行和止血等基本要素。结论:静脉动静脉畸形手术的成功与否,很大程度上取决于系统的计划和精确的执行。
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引用次数: 0
Arteriovenous fistulae of the neuraxis: An institutional experience 神经轴动静脉瘘:一个机构的经验
Pub Date : 2020-01-01 DOI: 10.4103/jcvs.jcvs_4_20
S. Ganapathy, S. Gopal, P. Pandey
Introduction: Arteriovenous fistulae (AVF) are rare lesions. Patients typically present with slowly progressive myelopathy that is often mistaken for degenerative cervical or lumbar stenosis. Cranial presentations are even more innocuous ranging from seizures to tinnitus. The purpose of this study is to present a series of cases to aid in the assessment, diagnosis and treatment of this unusual pathology. Case Series: We present 11 cases of AVFs treated at our centre over an 4-year period. Seventy percent of patients were male. The mean age of presentation was 62.6 years. The most common lesion was a dural AVF emanating from the craniovertebral junction with single feeder. All patients underwent either microsurgical correction or endovascular embolization as the primary procedure. Eight patients showed improvement following treatment as graded by the Nurick system. Two patients failed to improve. None of the patients worsened. One patient had a cortical venous thrombosis after embolization that resolved well with anticoagulants. Conclusion: The successful treatment of AVF requires a detailed understanding of clinical presentation and imaging findings to allow for precise treatment. Owing to the rarity of the condition, clinicians must continue to share their experiences to advance our knowledge.
摘要动静脉瘘是一种罕见的疾病。患者通常表现为缓慢进行性脊髓病,常被误认为退行性颈椎或腰椎管狭窄。颅脑表现甚至更无害,从癫痫发作到耳鸣。本研究的目的是提出一系列的病例,以帮助评估,诊断和治疗这种不寻常的病理。病例系列:我们报告了在我们中心治疗的4年期间的11例房颤。70%的患者是男性。平均发病年龄为62.6岁。最常见的病变是从颅椎交界处发出的硬脑膜AVF。所有患者均接受显微外科矫正或血管内栓塞作为主要手术。8名患者在接受Nurick系统分级治疗后表现出改善。两名患者没有好转。没有一个病人病情恶化。1例患者在栓塞后出现皮质静脉血栓形成,使用抗凝剂后解决良好。结论:成功治疗AVF需要详细了解临床表现和影像学表现,以便精确治疗。由于这种情况的罕见性,临床医生必须继续分享他们的经验,以提高我们的知识。
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引用次数: 0
A rare case of internal carotid artery trifurcation and an aneurysm associated with it 一个罕见的病例颈内动脉三岔和动脉瘤与它有关
Pub Date : 2020-01-01 DOI: 10.4103/jcvs.jcvs_21_20
Harsh Agrawal, J. Varghese, M. Balamurugan
Existing literature is devoid of data on true trifurcations of the internal carotid artery (ICA). The authors present a rare case of trifurcation of the ICA, discovered during the evaluation of a patient with subarachnoid haemorrhage, and discuss the surgical implications of the anomaly.
现有文献缺乏关于颈内动脉(ICA)真正三分岔的数据。作者提出了一个罕见的病例三岔的ICA,发现在评估患者蛛网膜下腔出血,并讨论异常的手术意义。
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引用次数: 0
From the editor's desk 从编辑的桌子上
Pub Date : 2020-01-01 DOI: 10.4103/jcvs.jcvs_12_20
J. Dil
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引用次数: 0
Acute neurovascular care in the COVID era: Safety and resilience COVID时代的急性神经血管护理:安全性和复原力
Pub Date : 2020-01-01 DOI: 10.4103/jcvs.jcvs_5_20
S. Paramasivam, Harihara Sudan, D. Babu, N. Kumar
Introduction: Since the outbreak of the coronavirus pandemic, much has changed in the protocol for management of healthcare setups and patients presenting with any illness including neurological and neurosurgical emergencies. Patients are themselves deterred from visiting a hospital in an emergency, and healthcare workers require stringent precautions and plans to prevent the spread of the virus to themselves and others, without compromising on the care that is to be provided. Aims and objectives: To outline the importance of identifying neurological emergencies requiring urgent intervention even in the time of a pandemic, and methods to effectively manage patients without compromising on safety and infection prevention measures. Materials: Guidelines reviewed from existing literature and retrospective analysis of management protocol and care delivered in a neurovascular unit during the COVID-19 pandemic.. Conclusion: Acute neurovascular care should not be compromised upon even during a pandemic, but neither should the safety of healthcare workers. Safety guidelines and protocols require strict adherence.
导言:自冠状病毒大流行爆发以来,医疗机构和包括神经和神经外科急诊在内的任何疾病患者的管理方案发生了很大变化。患者本身被阻止在紧急情况下去医院,卫生保健工作者需要严格的预防措施和计划,以防止病毒传播给自己和他人,同时不影响所提供的护理。目的和目标:概述即使在大流行期间也要确定需要紧急干预的神经紧急情况的重要性,以及在不影响安全和感染预防措施的情况下有效管理患者的方法。资料:根据现有文献审查指南,并对COVID-19大流行期间神经血管部门的管理方案和护理进行回顾性分析。结论:即使在大流行期间,急性神经血管护理也不应受到损害,但医护人员的安全也不应受到损害。安全指南和协议要求严格遵守。
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引用次数: 0
Stent-assisted aneurysm coiling of a complex A1–A2 aneurysm: A technically demanding but useful procedure in complex intracranial aneurysms 支架辅助的复杂A1-A2动脉瘤盘绕术:复杂颅内动脉瘤的一种技术要求高但有用的手术
Pub Date : 2020-01-01 DOI: 10.4103/jcvs.jcvs_2_20
S. Gopal, S. Ganapathy
Intracranial aneurysms are a subject of controversy. Anterior circulation aneurysms are usually considered surgical territory, yet endovascular prowess can affect good results with minimal morbidity and comparable long-term results. We present a complex anterior cerebral artery aneurysm that would require either a bypass or a complex vessel reconstructive procedure. Instead, we proceeded to perform a stent-assisted coiling trapping the coils inside the aneurysm through a covered stent, thereby ensuring vascular continuity and complete aneurysm control. A brief review of the literature is also added to put this report in perspective.
颅内动脉瘤是一个有争议的话题。前循环动脉瘤通常被认为是外科手术的领域,然而血管内的力量可以以最小的发病率和相当的长期效果影响良好的结果。我们提出了一个复杂的大脑前动脉瘤,需要搭桥或复杂的血管重建程序。取而代之的是,我们继续进行支架辅助盘绕术,通过覆盖支架将线圈困在动脉瘤内,从而确保血管的连续性并完全控制动脉瘤。对文献的简要回顾也被添加到这个报告的角度。
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引用次数: 0
期刊
Journal of Cerebrovascular Sciences
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