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Adenosine in facilitating aneurysm clipping: An institutional experience 腺苷促进动脉瘤夹闭:一个机构经验
Pub Date : 2021-07-01 DOI: 10.4103/jcvs.jcvs_3_22
G. Manoharan, R. Prasad, Senthil Kumar, K. Arvind
Introduction: Intracranial aneurysms are the one of most complicated conditions confronted by a neurosurgeon. Even though endovascular procedure is preferred, open surgery and clipping of the aneurysm still remains gold standard procedure for many aneurysms. Proximal control of the parent vessel remains one of the most critical steps in clipping the aneurysms and this can be achieved by various ways such as temporary clipping and transient cardiac standstill using adenosine. Temporary clipping is associated with complications such as infarct and injury to the vessel, whereas temporary hypotension using adenosine provides a way for successful clipping of the aneurysm. Here, we present our experience with adenosine in patients undergoing clipping of aneurysms in our institution between 2017 and 2020. Methodology: It is a retrospective cohort study conducted on patients undergoing craniotomy and clipping of aneurysms and in those where adenosine is not contraindicated. Patients are divided into Group A where adenosine is not used and Group B where adenosine is used. Results: In Group B, where adenosine is used, clipping was easier, with less incidence of intraoperative ruptures, less usage of Temporary clip (TC) and less incidence of infarct, reduce clipping time with no side effects. Conclusion: Adenosine-induced transient cardiac arrest and hypotension are a safe and effective method in facilitating aneurysm clipping.
颅内动脉瘤是神经外科医生面临的最复杂的疾病之一。尽管血管内手术是首选,开放手术和动脉瘤夹闭仍然是许多动脉瘤的金标准手术。近端控制母血管仍然是夹闭动脉瘤最关键的步骤之一,这可以通过多种方式实现,如使用腺苷进行临时夹闭和短暂性心脏停止。临时夹闭与梗塞和血管损伤等并发症有关,而使用腺苷临时降压为成功夹闭动脉瘤提供了一种方法。在这里,我们介绍了我们在2017年至2020年期间在我们机构接受动脉瘤夹闭的患者中使用腺苷的经验。方法:这是一项回顾性队列研究,对接受开颅手术和动脉瘤夹闭的患者以及无腺苷禁忌的患者进行研究。患者分为不使用腺苷的A组和使用腺苷的B组。结果:B组使用腺苷,夹夹更容易,术中破裂发生率更低,临时夹(TC)的使用更少,梗死发生率更低,夹夹时间缩短,无副作用。结论:腺苷诱导的短暂性心脏骤停和低血压是一种安全有效的动脉瘤夹闭方法。
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引用次数: 0
A concise operative atlas of microvascular decompression – Different intraoperative scenarios and technical nuances 微血管减压简明手术图谱-术中不同场景和技术差异
Pub Date : 2021-07-01 DOI: 10.4103/jcvs.jcvs_21_21
Roopesh Kumar, A. Karthikayan
Background: Trigeminal neuralgia is one of the most common facial pain syndromes. Although there are many postulated hypotheses explaining the pain, microvascular compression of the root entry zone (REZ) of the trigeminal nerve is commonly accepted to be the pathology for neuralgia. Various medical and surgical treatments are available to relieve the pain and microvascular decompression of the trigeminal nerve at the REZ is considered as the most successful modality and the gold standard. Methods: In this video atlas on operative nuances, we have described nine common scenarios that could be encountered during this surgery. Conclusion: Thorough knowledge of the different intraoperative scenarios is crucial for a complete microvascular decompression that translates into a good post-operative outcome.
背景:三叉神经痛是最常见的面部疼痛综合征之一。虽然有许多假设解释疼痛,微血管压迫的根进入区(REZ)的三叉神经是普遍接受的病理神经痛。有多种内科和外科治疗方法可用于减轻疼痛,在REZ对三叉神经进行微血管减压被认为是最成功的方式和金标准。方法:在这个关于手术细微差别的视频图集中,我们描述了手术中可能遇到的九种常见情况。结论:充分了解术中不同情况对于微血管完全减压和良好的术后预后至关重要。
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引用次数: 0
Clinical Significance of Serial Measurements of Interleukin-6 and High-Sensitivity C-Reactive Protein as Early Predictor of Poor Neurological Outcome in Aneurysmal Subarachnoid Haemorrhage 白细胞介素-6和高敏c反应蛋白系列检测作为动脉瘤性蛛网膜下腔出血神经预后不良的早期预测指标的临床意义
Pub Date : 2021-07-01 DOI: 10.4103/jcvs.jcvs_4_22
Amit Sharma, Ruhi Mamualiya, Rahul Inganal, Daljit Singh, B. Mahajan
Introduction: The inflammatory events are implicated in the pathophysiology of subarachnoid haemorrhage (SAH) and secondary brain injury. The goal of this study was to determine the role of interleukin-6 (IL-6) and high-sensitivity C-reactive protein (hsCRP) as an early predictor of the poor neurological outcome at 6 months in individuals with SAH. Methods: In this prospective, observational study of consecutive patients with aneurysmal SAH included over 1 year. Peak IL-6 and hsCRP were used as an indicator of the inflammatory response. Initial IL-6 and hs-CRP levels were collected within 12 h from admission and then for the next consecutive 7 days. The primary outcome was neurological status at 6-month follow-up assessed with the Modified Rankin Scale (0–6) with a score with or higher than 3 labelled as poor outcome. Logistic regression analyses were used to evaluate the associations between the peak serum IL-6 and hs-CRP levels and the neurological outcome. Results: The median peak levels of both markers were significantly higher in the poor outcome group on all 7 days. A significant correlation was seen between peak IL-6 and poor Hunt and Hess grade (P = 0.006), infarction (0.033) and systemic infection (0.03), whereas peak hsCRP had a correlation with rebleed (P = 0.017) and clipping (P = 0.032). Significant risk factors for the poor outcome were poor Hunt and Hess grade (P < 0.000) and high Fisher grades (P = 0.021) and peak IL-6 levels (P = 0.014) on regression analysis. Conclusion: The serial measurements of inflammatory markers IL-6 and hsCRP may be used to predict the neurological outcome in aSAH patients. The peak IL-6 levels correlated significantly with poor neurological outcome. Although hsCRP was elevated in patients with the poor outcome, it was statistically non-significant, suggesting a non-specific inflammatory stress response.
炎症事件与蛛网膜下腔出血(SAH)和继发性脑损伤的病理生理有关。本研究的目的是确定白细胞介素-6 (IL-6)和高敏c反应蛋白(hsCRP)作为SAH患者6个月时不良神经预后的早期预测因子的作用。方法:在这项前瞻性观察研究中,连续1年以上的动脉瘤性SAH患者。IL-6峰值和hsCRP作为炎症反应的指标。入院后12小时内采集初始IL-6和hs-CRP水平,然后连续7天采集。主要预后指标为6个月随访时的神经系统状况,采用改良兰金量表(Modified Rankin Scale, 0-6分)评估,评分大于或等于3分为不良预后。采用Logistic回归分析评估血清IL-6峰值和hs-CRP水平与神经预后之间的关系。结果:在所有7天中,两种标志物的中位峰值水平在不良结局组中均显著较高。IL-6峰值与Hunt和Hess评分差(P = 0.006)、梗死(0.033)和全身感染(0.03)有显著相关性,而hsCRP峰值与再出血(P = 0.017)和夹伤(P = 0.032)有显著相关性。不良预后的显著危险因素为Hunt和Hess评分差(P < 0.000)、Fisher评分高(P = 0.021)和IL-6峰值水平(P = 0.014)。结论:炎症标志物IL-6和hsCRP的系列测量可用于预测aSAH患者的神经预后。IL-6峰值水平与神经预后不良显著相关。虽然hsCRP在预后较差的患者中升高,但在统计学上不显著,提示非特异性炎症应激反应。
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引用次数: 0
Combined Sub-temporal and Pterional Exposure for Clipping of Posterior Cerebral Artery Aneurysm 颞下翼点联合暴露夹持大脑后动脉动脉瘤
Pub Date : 2021-07-01 DOI: 10.4103/jcvs.jcvs_1_22
G. Menon, A. Varsha, Vinod Kumar, Ajay Hegde
Posterior cerebral aneurysms are rare posterior circulation aneurysms. Clinical presentation can be varied from life-threatening subarachnoid hemorrhage to mass effect on adjacent structures. Due to their complex anatomical location, microsurgical clipping is not without challenges. Several approaches have been described based on the location of the aneurysm in relation to the segment of the posterior cerebral artery (PCA). We describe a combined approach for surgical clipping of a postcommunicating anterior segment PCA aneurysm.
脑后动脉瘤是一种罕见的后循环动脉瘤。临床表现可从危及生命的蛛网膜下腔出血到相邻结构的肿块效应。由于其复杂的解剖位置,显微手术夹并非没有挑战。根据动脉瘤与脑后动脉(PCA)段的关系,已经描述了几种方法。我们描述了一种联合入路手术夹闭交通后前段PCA动脉瘤。
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引用次数: 0
Spontaneous thrombosis of internal carotid artery with occlusion of giant cavernous carotid aneurysm and malignant hemispheric infarct – Cure or curse? 颈内动脉自发性血栓形成伴巨海绵状动脉瘤闭塞和恶性半球性梗死——治愈还是诅咒?
Pub Date : 2021-07-01 DOI: 10.4103/jcvs.jcvs_23_21
G. Menon, A. Pradhan, Ajay Hegde
Spontaneous thrombosis of giant intracranial aneurysm with parent artery occlusion is uncommon. We present an unusual case of a 28-year-old female who presented with a hemispheric infarct probably secondary to dissection of the cervical internal carotid artery (ICA). The cervical ICA occlusion simultaneously induced total thrombosis of pre-existing incidental giant cavernous ICA aneurysm. We discuss the various theories and probable mechanisms involved.
巨大颅内动脉瘤自发性血栓形成伴载动脉闭塞并不常见。我们提出一个不寻常的情况下,一位28岁的女性谁提出了一个半球梗死可能继发于颈内动脉剥离(ICA)。颈内动脉闭塞术同时引起原有的偶发性颈内动脉巨海绵状动脉瘤全血栓形成。我们讨论了各种理论和可能的机制。
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引用次数: 1
Torcular herophili dural arteriovenous fistula of the brain – Balloon-assisted flow-controlled embolisation with venous sinus preservation 脑圆形嗜herophili硬脑膜动静脉瘘-球囊辅助血流控制栓塞与静脉窦保存
Pub Date : 2021-07-01 DOI: 10.4103/jcvs.jcvs_9_22
S. Paramasivam, Kannah Elangovan
Dural arteriovenous fistulas (DAVF) are rare acquired vascular malformations of the brain with varied clinical presentations based on the location and pattern of venous drainage. Aggressive management of DAVF is predominantly endovascular with open surgical obliteration reserved for a few selected cases. DAVF around the trocular herophili are challenging as we need to preserve the superficial and deep venous channels for the normal drain drainage. We describe a case of complex DAVF centered around torcula herophili and left transverse sinus with complete obliteration of left sigmoid sinus and stenosis of the left transverse sigmoid sinus. The DAVF had retrograde venous drainage through the superficial and deep venous sinuses, cortical veins, competing with normal venous drainage of the brain with significant venous hypertension and cognitive impairment. Our goal was complete obliteration of all the feeders with preservation of the venous sinuses and reduction of venous hypertension to achieve cognitive improvement. Endovascular embolisation by transarterial route was done with flow control on the venous side using dimethyl sulfoxide compatible balloon. We have described the technical challenges and strategy to achieve complete obliteration of all the feeders around the sinus, with preservation of torcula using balloon inflation. Venous system flow was restored to the normal pattern and anti-coagulated for 24 h. Endovascular embolisation is the mainstay treatment for DAVF. To achieve cure, strategising the approach and extent of obliteration based on anatomy and venous drainage pattern of the brain is essential. Torcular DAVF pose a specific challenge, at it is the confluence of the superficial and deep venous system. Transvenous Balloon-assisted embolisation is a safe and effective method to achieve complete obliteration of DAVF with preservation of the venous sinuses.
硬脑膜动静脉瘘(DAVF)是一种罕见的脑部获得性血管畸形,其临床表现因静脉引流的位置和模式而异。DAVF的积极治疗主要是血管内手术,开放手术闭塞保留给少数选定的病例。由于我们需要保留浅静脉通道和深静脉通道以保持正常的引流,因此在嗜肾环周围的DAVF是具有挑战性的。我们报告一例复杂的以嗜黑环和左横窦为中心的左乙状窦完全闭塞和左乙状窦狭窄。DAVF通过浅静脉窦、深静脉窦、皮质静脉逆行静脉引流,与正常的脑静脉引流竞争,伴有明显的静脉高压和认知障碍。我们的目标是在保留静脉窦和减少静脉高压的情况下完全阻断所有的喂食器,以达到改善认知的目的。经动脉血管内栓塞,使用二甲亚砜相容球囊控制静脉侧血流。我们描述了技术上的挑战和策略,以实现窦周围所有喂食器的完全闭塞,并使用球囊充气保存环。静脉系统血流恢复到正常模式并抗凝24小时。血管内栓塞是DAVF的主要治疗方法。为了达到治愈的目的,根据解剖结构和脑静脉引流模式来确定闭塞的方法和范围是必不可少的。圆形DAVF提出了一个特殊的挑战,因为它是浅静脉系统和深静脉系统的交汇处。经静脉球囊辅助栓塞是一种安全有效的方法,可以在保留静脉窦的情况下实现DAVF的完全闭塞。
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引用次数: 0
Practicality of aneurysm clipping over coiling in semi-urban and rural India 在印度的半城市和农村地区,动脉瘤切开术的实用性
Pub Date : 2021-07-01 DOI: 10.4103/jcvs.jcvs_12_22
J. Dil
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引用次数: 0
Pseudo-hyperdense MCA sign: The value of comparing CT densities of vessels on both sides 伪MCA高密度征:比较两侧血管CT密度的价值
Pub Date : 2021-01-01 DOI: 10.4103/jcvs.jcvs_5_21
P. Krishnan
Hyperdense middle cerebral artery (MCA) sign is a well-recognised sign of stroke radiology. However, less often reported is the pseudo 'hyperdense MCA sign' that looks ominous and may confound the clinician into thinking that he is dealing with a case of ischaemic stroke. We report a 56-year-old male who nearly underwent thrombolysis due to this sign seen on initial computed tomography imaging and highlight the way to avoid this pitfall.
大脑中动脉(MCA)高密度征象是卒中放射学中公认的征象。然而,伪“MCA高密度征象”的报道较少,它看起来不太好,可能使临床医生认为他正在处理一个缺血性中风的病例。我们报告一位56岁的男性患者,由于在最初的计算机断层扫描成像中看到这个征象,几乎接受了血栓溶解,并强调了避免这个陷阱的方法。
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引用次数: 0
A giant spontaneous dural arteriovenous fistula of the spheno-parietal sinus clinically masquerading as carotico-cavernous fistula: A case report 蝶顶窦巨大自发性硬脑膜动静脉瘘临床伪装为颈海绵状瘘1例
Pub Date : 2021-01-01 DOI: 10.4103/jcvs.jcvs_9_21
D. Mahakul, Rahul Inganal, Daljit Singh
Dural arteriovenous fistulas (DAVF) are abnormal connections between the feeding arteries and veins within the dural leaflets and constitute 10%–15% of all intracranial arteriovenous malformations. DAVF draining into sphenoparietal sinus is a rare pathologic entity that is fed by the middle meningeal artery and is associated with a history of prior trauma. We report a unique case of DAVF of sphenoparietal sinus that had developed spontaneously. Being giant in morphology, it had eroded into the orbit and presented with proptosis, chemosis and restriction of eye movement. Although the clinical findings pointed towards caroticocavernous fistula, the real pathomorphology was unveiled by the six-vessel catheter angiography with selective catheterisation of smaller feeding vessels. All the feeding vessels were meticulously mapped out, and the fistulous connection was vividly identified and subsequently obliterated using detachable coils and n-butyl cyanoacrylate.
硬脑膜动静脉瘘(DAVF)是硬脑膜小叶内供血动脉和静脉之间的异常连接,占颅内动静脉畸形的10%-15%。DAVF流入蝶顶窦是一种罕见的病理实体,由脑膜中动脉供血,并与先前的创伤史有关。我们报告一个独特的病例DAVF的蝶顶窦已经自发发展。形态巨大,已侵蚀入眼眶,眼球突出、化脓、眼球运动受限。虽然临床表现指向颈海绵窦瘘,但真正的病理形态是通过六血管导管血管造影(选择性导管置入较小的喂养血管)揭示的。所有的喂养血管都被精心绘制出来,瘘连接被生动地识别出来,随后使用可拆卸线圈和氰基丙烯酸酯正丁酯清除。
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引用次数: 0
Surgical nuances of clip reconstruction of recurrent middle cerebral artery aneurysms: A technical note 复发性大脑中动脉瘤夹片重建的手术细节:技术注意事项
Pub Date : 2021-01-01 DOI: 10.4103/jcvs.jcvs_17_21
Aravind Sabesan, Y. Kato, T. Kawase, Yasuhiro Yamada, Riki Tanaka
Recurrence of an aneurysm is not frequently seen after microsurgical clipping. The exact incidence is varied among studies related to recurrent aneurysms from 0.02% to 0.52%. A 68-year-old male, diagnosed with unruptured left middle cerebral artery (MCA) aneurysm 8 years back, was treated by microsurgical clipping then. He was on periodic follow-up since. On yearly follow-up, in 2015, magnetic resonance imaging/magnetic resonance angiography showed small recurrent aneurysm. This was followed up with serial imaging, and the aneurysm slowly grew in size. 2 years after, he was found to have a recurrent aneurysm; in 2017, he was operated for the recurrent aneurysm with microsurgical clipping. Here, we report the technical difficulties and strategies to approach recurrent MCA aneurysm.
显微手术夹闭后动脉瘤复发并不常见。在与复发性动脉瘤相关的研究中,确切的发生率从0.02%到0.52%不等。68岁男性,8年前确诊为左大脑中动脉(MCA)动脉瘤未破裂,行显微手术夹持治疗。从那以后,他定期接受随访。在2015年的年度随访中,磁共振成像/磁共振血管造影显示小动脉瘤复发。随后进行了一系列成像,动脉瘤慢慢变大。2年后,他被发现有复发性动脉瘤;2017年,他接受了显微外科手术,治疗复发性动脉瘤。在此,我们报告处理复发性MCA动脉瘤的技术困难和策略。
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引用次数: 0
期刊
Journal of Cerebrovascular Sciences
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