Sleep and Biological Rhythms最新文献

[This corrects the article DOI: 10.1007/s41105-025-00618-4.].

There is no consensus on whether to use continuous positive airway pressure (CPAP) treatment for mild obstructive sleep apnea syndrome (OSAS). Our study aims to observe the efficacy and necessity of using CPAP treatment in mild OSAS patients complicated with subjective cognitive decline (SCD). From August 2021 to July 2022, patients with mild OSAS and SCD were randomized to the control group or the CPAP group, and followed up for 3 months. The primary results were evaluated using subjective cognitive decline questionnaire (SCD-Q), the Huashan version of the Auditory Verbal Learning Test (AVLT-H), and animal fluency test (AFT), which were tested at admission and three months after treatment, respectively. And plasma Aβ1-40 and Aβ1-42 levels were also measured at admission and 3 months after treatment. A total of 110 patients completed the final study, with 55 in the control group and 55 in the CPAP group. No significant differences in demographic data, Laboratory tests, AHI index, SCD-Q, AVLT-H, and AFT scores between the two groups before treatment. The SCD-Q score of patients in CPAP group significantly decreased after 3 months of treatment and was significantly lower than that of control group (P<0.05). And the immediate memory score of AVLT-H in the treatment group was significantly increased after 3 months of treatment (P < 0.05). The Aβ1-42/Aβ1-40 ratio in the treatment group significantly decreased after 3 months of treatment, and was significantly lower than that of control group (P<0.05). Furthermore, there was linear correlation between SCD-Q score and Aβ1-42/Aβ1-40 ratio in all patients after 3 months of treatment (P<0.001, r=0.584). Our findings suggested that CPAP treatment can significantly decrease the Aβ1-42/Aβ1-40 ratio, and improve SCD, which may play an important role in the prevention of dementia, but further research are warranted.

Supplementary information: The online version contains supplementary material available at 10.1007/s41105-025-00620-w.

The Pittsburgh sleep quality index (PSQI) is one of the most widely used instruments to assess sleep quality. This study aimed to translate the PSQI into Bangla (PSQI-BN) and evaluate its psychometric properties among Bangladeshi population. This cross-sectional study was conducted in two phases. In the first phase, the PSQI was translated into Bangla following standard guidelines. In the second phase, the psychometric properties of the PSQI-BN were evaluated, including content validity, construct validity (convergent and divergent), internal consistency, and test-retest reliability. An exploratory factor analysis was also conducted. A sample of 148 apparently healthy individuals were included in the study. The PSQI-BN demonstrated moderate internal consistency (Cronbach's α = 0.619) and strong test-retest reliability (Spearman's ρ = 0.842, p < 0.001). The PSQI-BN total score showed a moderate positive correlation (ρ = 0.369, p < 0.001) with the Insomnia Severity Index-Bangla, indicating convergent validity, and a weak positive correlation (ρ = 0.286, p < 0.001) with the Perceived Stress Scale, suggesting divergent validity. Exploratory factor analysis revealed a four-factor structure, representing onset and fragmentation, sleep sufficiency, subjective restoration, and medication-assisted sleep. The biplot analysis confirmed the representation of each component within the factor structure, with sleep duration, sleep latency, sleep disturbance, and sleep efficiency having the highest representation. This study provides initial evidence supporting the reliability and validity of the PSQI-BN as a measure of sleep quality in the Bangladeshi population. The availability of a culturally adapted and psychometrically evaluated Bangla version of the PSQI will facilitate high-quality sleep research and clinical applications in Bangladesh.

Ramadan fasting introduces significant disruptions to sleep and nutrition, posing potential challenges for athletes who must maintain both cognitive and physical performance. While fasting alone has been suggested to have minimal cognitive impact, sleep deprivation during Ramadan remains an understudied factor in athletic performance. This study aimed to investigate the independent and combined effects of sleep restriction and fasting on cognitive performance in elite athletes. A within-subject, repeated-measures design was employed, with 41 elite athletes completing three conditions: (1) Well-Rested Fed (WR-Fed), (2) Well-Rested Fasted (WR-Fast), and (3) Sleep-Restricted Fasting (SR-Fast). The WR-Fed condition was assessed before Ramadan under habitual sleep and eating patterns, while the Ramadan conditions (WR-Fast and SR-Fast) were conducted during the first week of fasting. Sleep duration was objectively tracked using Apple Watches, and cognitive performance was assessed using the Psychomotor Vigilance Test (PVT), Upper-Body Reaction Time, and Go/No-Go Test. A repeated-measures ANOVA was used to analyze cognitive performance across conditions. Athletes in the SR-Fast condition exhibited significantly slower reaction times, greater reaction time variability, and an increased number of lapses compared to both WR-Fed and WR-Fast conditions (p < .05). WR-Fast led to mild impairments in reaction time variability and lapses, the magnitude of these effects was considerably smaller than those induced by sleep restriction. These findings provide novel insights into the neurocognitive effects of Ramadan and underscore the need for tailored interventions to support athletic performance under combined sleep and nutritional stress.

REM sleep behavior disorder (RBD) frequently co-occurs with obstructive sleep apnea (OSA), with up to 90% of RBD patients having concurrent OSA. OSA-related sleep fragmentation may exacerbate RBD symptoms through disruption of REM sleep architecture. While continuous positive airway pressure (CPAP) is the gold standard for OSA treatment, its effects on RBD symptoms are not well characterized. This systematic review evaluated CPAP therapy effectiveness for improving RBD symptoms in patients with concurrent RBD and OSA. We conducted a systematic review in accordance with PRISMA guidelines, searching MEDLINE, EMBASE, and Cochrane databases from inception through July 2025. Studies were eligible if they evaluated the effect of CPAP on RBD symptoms in patients with both disorders, used validated diagnostic criteria, and reported relevant treatment outcomes. Study quality was assessed using the Newcastle-Ottawa Scale. Three observational studies comprising 377 patients met inclusion criteria. CPAP therapy was associated with variable improvement in RBD symptoms, with response rates ranging from 45.8% to 74.2%. Potential predictive factors for treatment success included an apnea-hypopnea electromyography (AH-EMG) activity ratio ≥ 15% (OR = 10.146, 95% CI: 1.2-83.3, p = 0.032) and a REM apnea-hypopnea index (AHI) ≥ 10 events per hour. A dose-response relationship was observed, with adherent CPAP users showing 35.0% reduction in dream enactment behaviors compared with 13.3% among non-users. Preliminary evidence suggests CPAP therapy may provide clinically meaningful improvement in RBD symptoms for patients with concurrent OSA. However, the limited evidence base consisting of only observational studies precludes definitive conclusions. The identified predictive factors and adherence-response relationship warrant further investigation through randomized controlled trials.

Supplementary information: The online version contains supplementary material available at 10.1007/s41105-025-00616-6.

[This corrects the article DOI: 10.1007/s41105-025-00612-w.].

Purpose: To clarify the relationship between electroencephalograms (EEGs) and video-identified behavioral signs of microsleep.

Methods: EEGs during each behavior were evaluated using two maintenance of wakefulness test (MWT) cases with whole-body video monitoring.

Results: In MWTs, 30.3% and 60.5% of the behavioral signs of microsleep corresponded to alpha waves and microsleep, respectively. We demonstrated that EEG frequency decelerated during behavioral signs of microsleep compared to that while awake. Slow eye movements on the electrooculogram preceded or coincided with behavioral signs of microsleep corresponding to EEG microsleep.

Conclusions: EEG frequency deceleration could be inferred from behavioral assessments based on whole-body video monitoring.

Supplementary information: The online version contains supplementary material available at 10.1007/s41105-025-00613-9.

The present study examined the extent to which overall sleep quality, resilience, and hardiness affect stress responses over the previous two to three days among Japanese university students. An online, anonymous questionnaire was administered, collecting demographic data and responses to the Japanese versions of the Pittsburgh Sleep Quality Index (PSQI), Resilience Scale for Students (RS-S), Hardiness Scale (HS), and Stress Response Scale-18 (SRS-18) scales. Four hierarchical linear multiple regression analyses were conducted using the SRS-18 total score and its subscales (Depression-Anxiety, Irritability-Anger, and Helplessness scores) as objective variables. Explanatory variables were the Global RS-S score, RS-S score, and HS score, with sex, age, and the survey period as confounding variables. In the analysis with the SRS-18 total score as the objective variable, the PSQI score (β = 0.28) and RS-S score (β = -0.28) both showed significant effects, whereas the HS score (β = -0.11) did not. Results remained stable after controlling for confounders. Similar results were obtained for the Depression-Anxiety and Irritability-Anger scores, but not for the Irritability-Anger score: PSQI (β = 0.18), RS-S (β = -0.19), HS (β = -0.06). Overall sleep quality affected short-term stress responses to a similar degree as resilience, particularly regarding Depression-Anxiety and Irritability-Anger.