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Rectal Spacer Reduces Gastrointestinal Side Effects of Radiation Post Radical Prostatectomy 直肠垫片可减少根治性前列腺切除术后放射治疗的胃肠道副作用
Pub Date : 2024-04-16 DOI: 10.3390/siuj5020020
Anne Hong, Damien Bolton, T. Phạm, D. Angus, David Pan, D. L. Joon, A. Tan, Kevin McMillan, Y. Chan, Paul Manohar, Joe Thomas, H. Ho, Peter Orio, Emily Holt, M. Cokelek, Nathan Lawrentschuk, F. Foroudi, Michael Chao
Objectives: Our objective was to assess the rate of complications and gastrointestinal adverse effects of rectal spacer insertion for salvage post prostatectomy radiation therapy. Methods: A retrospective observational study was performed. Between September 2018 and March 2022, 64 post-radical prostatectomy patients who were planned for salvage radiation therapy received a rectal spacer. The selected patients were those who had nerve-sparing prostatectomy with intrafascial or interfascial dissections (where Denonvillier’s fascia is retained). Radiation dose to the rectal wall and gastrointestinal symptoms were assessed. Symptoms were graded using the National Cancer Center Institute Common Terminology Criteria for Adverse Events v4.0 grading scheme. A total of 39 patients had pre-spacer planning computer tomography (CT) scans, and the rectal dose before and after the spacer insertion was calculated. Comparisons were made using the Student’s t-test, with a p-value < 0.05 representing statistical significance. Finally, clinicians were surveyed to rate the ease of the procedure using a 5-point Likert scale of 1 to 5 (1: very difficult, 2: difficult, 3: moderate, 4: easy, 5: very easy). Results: A total of 64 patients successfully underwent rectal spacer insertion. The mean age was 64.4 years (standard deviation: 5.7 years). After a median of 14 months’ (range 6 to 35) follow up, acute grade 1 and above gastrointestinal (GI) toxicities were seen in 28% of patients (grade 2 in 1.5%), and late grade 1 and above GI toxicities were seen in 12% of patients (grade 2 in 1.5%). Amongst the 39 patients with pre-spacer planning CT images, the volume of the rectum receiving 60%, 70%, 80%, 90%, and 100% of the prescribed radiation dose was reduced by 25.9%, 34.2%, 35.4%, 43.7%, and 61.7%, respectively. All dose reductions were statistically significant. The procedure was rated as “easy” or “very easy” to perform in 56% of cases. Conclusions: The insertion of a rectal spacer in selected patients undergoing PPRT is feasible and safe and significantly improves rectal wall radiation dosimetry in salvage post prostatectomy radiation therapy. It was accomplished in >95% of patients, increasing vesico-rectal separation from ‘immediate vicinity’ to 11 mm without any post-operative complications in experienced hands. In addition, it achieved significant reduction in rectal radiation doses, leading to low rates of acute and late grade 2 toxicity.
目的:我们的目的是评估前列腺切除术后放射治疗中插入直肠垫片的并发症发生率和胃肠道不良反应。方法: 我们进行了一项回顾性观察研究:我们进行了一项回顾性观察研究。2018年9月至2022年3月期间,64名前列腺根治术后患者计划接受挽救性放疗,并接受了直肠间隔器。所选患者均接受了筋膜内或筋膜间切除术(保留德农维利耶筋膜)的保神经前列腺切除术。对直肠壁的辐射剂量和胃肠道症状进行了评估。症状采用美国国家癌症中心研究所不良事件通用术语标准 v4.0 分级方案进行分级。共有 39 名患者接受了植入前计算机断层扫描(CT),并计算了植入前和植入后的直肠剂量。比较结果采用学生 t 检验,P 值小于 0.05 代表统计学意义显著。最后,对临床医生进行了调查,采用 1-5 级李克特 5 点量表(1:非常困难;2:困难;3:中等;4:容易;5:非常容易)对手术的难易程度进行评分。结果共有 64 名患者成功接受了直肠间隔器植入手术。平均年龄为 64.4 岁(标准差:5.7 岁)。经过中位 14 个月(6 至 35 个月)的随访,28% 的患者出现急性 1 级及以上胃肠道毒性反应(1.5% 出现 2 级),12% 的患者出现晚期 1 级及以上胃肠道毒性反应(1.5% 出现 2 级)。在 39 名有前间隔规划 CT 图像的患者中,接受 60%、70%、80%、90% 和 100% 规定辐射剂量的直肠体积分别减少了 25.9%、34.2%、35.4%、43.7% 和 61.7%。所有剂量的减少都具有显著的统计学意义。56%的病例认为手术 "容易 "或 "非常容易 "完成。结论在接受前列腺切除术后放射治疗的特定患者中插入直肠间隔器是可行和安全的,并能显著改善前列腺切除术后挽救性放射治疗中的直肠壁放射剂量测定。95%以上的患者都能做到这一点,经验丰富的医生可将膀胱直肠间距从 "邻近 "增加到 11 毫米,且不会出现任何术后并发症。此外,它还大大减少了直肠辐射剂量,从而降低了急性和晚期二级毒性的发生率。
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引用次数: 0
Role of Multiparametric Magnetic Resonance Imaging and Targeted Biopsy in the Detection of Clinically Significant Prostate Cancer in Patients with Suspicious Digital Rectal Examination 多参数磁共振成像和靶向活检在发现数字直肠指检可疑患者中具有临床意义的前列腺癌中的作用
Pub Date : 2024-04-16 DOI: 10.3390/siuj5020021
V. Ficarra, Alessandro Buttitta, M. Rossanese, A. Alibrandi, Giuseppina Anastasi, Alfredo Blandino, Antonio Ieni, M. Martini, G. Giannarini
Objectives: Few studies have examined the role of prostate MRI in patients with suspicious digital rectal examination (DRE) and/or PSA > 10 ng/mL. In a cohort of non-screened patients with suspicious DRE, we investigated the rate of avoidable prostate biopsies and potentially missed clinically significant prostate cancer (csPCa) with negative MRI, and the concordance between targeted biopsy (TBx) and systematic biopsy (SBx) in detecting csPCa with positive MRI. Methods: We retrospectively examined 199 biopsy-naïve patients with suspicious DRE who underwent prostate MRI before transperineal biopsy. Prostate Imaging—Reporting and Data System (PI-RADS) v2.1 ≥ 3 category of the index lesion defined a positive MRI. Combined TBx/SBx and SBx alone were performed for positive and negative MRI, respectively. An International Society of Urogenital Pathology Grade Group ≥ 2 defined csPCa. We calculated the csPCa detection rate of TBx, SBx, and combined TBx/SBx. The Cohen kappa statistic was used to measure the concordance between TBx and SBx. Results: Ninety-one (45.7%) csPCa cases were detected. MRI was positive in 153 (76.9%) patients. In the 46 patients with negative MRI, SBx detected 5 (10.9%) csPCa cases. Prostate biopsy could, thus, be avoided in 41/199 (20.6%) patients at the cost of missing 5/91 (5.5%) csPCa cases. The concordance between TBx and SBx in detecting csPCa with positive mpMRI was substantial (k = 0.70). Specifically, 6/86 (6.9%) csPCa cases were detected with TBx, and 17/86 (19.7%) with SBx alone. Concordance was almost perfect (k = 0.82) in patients with PSA > 10 ng/mL. Only 4/38 (10.5%) csPCa cases were missed by TBx, and only 1 (2.6%) csPCa case was identified by TBx alone. Conclusions: MRI in patients with suspicious DRE could avoid roughly 21% of unnecessary biopsies at the cost of missing approximately 6% of csPCa cases. Moreover, MRI and TBx complemented SBx in detecting csPCa in the subgroup with PSA > 10 ng/mL.
目的:很少有研究探讨前列腺磁共振成像在可疑数字直肠指诊(DRE)和/或PSA > 10 ng/mL患者中的作用。在一组未接受筛查的可疑 DRE 患者中,我们调查了 MRI 阴性时可避免的前列腺活检率和可能漏诊的有临床意义的前列腺癌(csPCa)率,以及靶向活检(TBx)和系统活检(SBx)在检测 MRI 阳性的 csPCa 时的一致性。方法:我们回顾性研究了 199 例未经活检的可疑 DRE 患者,这些患者在经会阴活检前接受了前列腺 MRI 检查。前列腺影像报告和数据系统(PI-RADS)v2.1 版≥ 3 级的指数病变定义为 MRI 阳性。对于 MRI 阳性和阴性,分别进行 TBx/SBx 联合术和单纯 SBx 术。国际泌尿生殖系统病理学学会分级组≥2级定义为csPCa。我们计算了 TBx、SBx 和联合 TBx/SBx 的 csPCa 检出率。Cohen kappa统计量用于衡量TBx和SBx之间的一致性。结果:共检测出 91 例(45.7%)csPCa。153例(76.9%)患者的磁共振成像呈阳性。在 46 例磁共振成像呈阴性的患者中,SBx 检测出 5 例(10.9%)csPCa。因此,41/199(20.6%)例患者可以避免前列腺活检,但却错过了 5/91 (5.5%)例 csPCa。TBx 和 SBx 在检测 mpMRI 阳性的 csPCa 方面具有很高的一致性(k = 0.70)。具体而言,6/86(6.9%)个 csPCa 病例是通过 TBx 检测到的,17/86(19.7%)个病例是仅通过 SBx 检测到的。PSA > 10 ng/mL 的患者几乎完全一致(k = 0.82)。仅有 4/38 例(10.5%)csPCa 病例因 TBx 而漏诊,仅有 1 例(2.6%)csPCa 病例因单独使用 TBx 而被发现。结论:对有可疑 DRE 的患者进行磁共振成像可避免约 21% 的不必要活检,但代价是错过了约 6% 的 csPCa 病例。此外,在 PSA > 10 ng/mL 的亚组中,MRI 和 TBx 对 SBx 检测 csPCa 起着互补作用。
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引用次数: 0
Dr. Samuel Henry (Harry) Harris (22 August 1881 to 25 December 1936) 塞缪尔-亨利(哈里)-哈里斯博士(1881 年 8 月 22 日至 1936 年 12 月 25 日)
Pub Date : 2024-04-12 DOI: 10.3390/siuj5020019
Darshan Sitharthan, Andrew Mitterdorfer
In the original article [...]
原文如下 [...]
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引用次数: 0
Can Artificial Intelligence Treat My Urinary Tract Infections?—Evaluation of Health Information Provided by OpenAI™ ChatGPT on Urinary Tract Infections 人工智能能否治疗我的尿路感染?--对 OpenAI™ ChatGPT 提供的尿路感染健康信息的评估
Pub Date : 2024-04-11 DOI: 10.3390/siuj5020018
K. Y. Zhuo, Paul Kim, J. Kovacic, Venu Chalasani, Krishan Rasiah, Stuart Menogue, Amanda Chung
Urinary tract infections (UTIs) are highly prevalent and have significant implications for patients. As internet-based health information becomes more relied upon, ChatGPT has emerged as a potential source of healthcare advice. In this study, ChatGPT-3.5 was subjected to 16 patient-like UTI queries, with its responses evaluated by a panel of urologists. ChatGPT can address general UTI questions and exhibits some reasoning capacity in specific contexts. Nevertheless, it lacks source verification, occasionally overlooks vital information, and struggles with contextual clinical advice. ChatGPT holds promise as a supplementary tool in the urologist’s toolkit, demanding further refinement and validation for optimal integration.
尿路感染(UTI)发病率很高,对患者有很大影响。随着人们越来越依赖基于互联网的健康信息,ChatGPT 已成为医疗保健建议的潜在来源。在这项研究中,ChatGPT-3.5 接受了 16 个类似 UTI 的病人询问,并由泌尿科专家小组对其回答进行了评估。ChatGPT 可以解决一般的 UTI 问题,并在特定情况下表现出一定的推理能力。不过,它缺乏来源验证,偶尔会忽略重要信息,并且在根据上下文提供临床建议方面存在困难。ChatGPT 有望成为泌尿科医生工具包中的辅助工具,但需要进一步完善和验证,以实现最佳整合。
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引用次数: 0
Beware of Bipolar Transurethral Resection of Prostate in Patients with Previously Inserted Metallic Prostate Stapling Devices 警惕曾植入金属前列腺缝合器的患者进行双极经尿道前列腺切除术
Pub Date : 2024-04-10 DOI: 10.3390/siuj5020017
Jianliang Liu, Nathan Lawrentschuk, Dixon T S Woon
Metallic prostate stapling (e.g., UroLift) is a minimally invasive treatment option for men with bladder outlet obstruction from benign prostatic hyperplasia (BPH). While it provides rapid relief and preserves sexual function, unexpected interactions with other medical devices can compromise surgical procedures. In this letter, we highlight five cases where stapled metallic implants resulted in damage to bipolar energy device during transurethral resection of the prostate (TURP) and stimulation of obturator nerve. Laser may also reflect off metallic prostate implants which can result in laser equipment malfunction. Monopolar TURP should be considered in patients with existing metallic prostate implants who need further transurethral surgery for obstructive BPH to prevent bipolar instrument damage and obturator kick.
金属前列腺缝合术(如 UroLift)是一种微创治疗方法,适用于因良性前列腺增生症(BPH)导致膀胱出口梗阻的男性。虽然它能迅速缓解症状并保留性功能,但与其他医疗设备的意外相互作用可能会影响手术过程。在这封信中,我们重点介绍了五例在经尿道前列腺切除术(TURP)和刺激闭孔神经的过程中,订书钉金属植入物导致双极能量装置受损的病例。激光还可能反射金属前列腺植入物,导致激光设备故障。对于已有金属前列腺植入物、需要进一步经尿道手术治疗阻塞性良性前列腺增生症的患者,应考虑采用单极前列腺切除术,以防止双极器械损坏和闭孔神经损伤。
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引用次数: 0
Smoking Cessation Tools in the Urological Context: Considering the Genitourinary Impacts of Smoking Cessation Tools 泌尿科背景下的戒烟工具:考虑戒烟工具对泌尿生殖系统的影响
Pub Date : 2024-04-09 DOI: 10.3390/siuj5020016
N. Bandara, Xuan Randy Zhou, Abdullah Alhamam, Peter C. Black, Marie-Pier St-Laurent
Electronic cigarette use is rising globally. Although it may represent a potential smoking cessation tool, amidst misinformation and social media promotion, there is a growing concern regarding the health risks associated with its usage. These risks include adverse effects on the genitourinary system. This commentary investigates the genitourinary effects of approved smoking cessation tools versus electronic cigarettes, urging urologists to prioritize established methods over electronic cigarettes due to their potential for multisystem toxicity and uncertain long-term health implications. Further research is warranted to evaluate comprehensively the genitourinary effects of these interventions.
电子香烟的使用在全球范围内呈上升趋势。虽然电子烟可能是一种潜在的戒烟工具,但在错误信息和社交媒体的宣传下,人们越来越关注使用电子烟带来的健康风险。这些风险包括对泌尿生殖系统的不良影响。这篇评论调查了已获批准的戒烟工具与电子香烟对泌尿生殖系统的影响,敦促泌尿科医生优先考虑成熟的戒烟方法,而不是电子香烟,因为电子香烟具有潜在的多系统毒性,对健康的长期影响也不确定。有必要开展进一步研究,以全面评估这些干预措施对泌尿生殖系统的影响。
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引用次数: 0
Is the Bulbar Urethral Stricture a Single and Uniform Disease? 球部尿道狭窄是一种单一且统一的疾病吗?
Pub Date : 2024-04-04 DOI: 10.3390/siuj5020014
Tadashi Tabei, A. Horiguchi, M. Shinchi, Y. Hirano, K. Ojima, Keiichi Ito, R. Azuma
Objectives: Proximal and distal bulbar urethral strictures (BUS) have different disease characteristics and require different treatment strategies despite being regarded as a single condition. To clarify the differences, we analyzed our database by distinguishing the two types of BUS. Methods: We retrospectively reviewed the data of 196 patients with BUS who underwent urethroplasty at the National Defense Medical College (Japan) between August 2004 and March 2022. We divided patients into proximal (group 1) or distal (group 2) groups based on the stricture segment and compared patient background and surgical techniques for each group. We assessed whether the stricture segment was an independent predictive factor for substitution urethroplasty selection using multivariate logistic regression analysis. The recurrence rates were calculated and compared using the Kaplan–Meier method and log-rank test, respectively. Results: Patients in group 1 had a less frequent non-obliterated lumen (73% vs. 94%, p = 0.020) and significantly shorter strictures (10 mm vs. 23 mm, p < 0.001) more frequently caused by external traumas (47% vs. 26%, p = 0.010) than those in group 2. Logistic regression analysis revealed that the stricture segment (distal) (p < 0.001), stricture length (≥20 mm) (p < 0.001), ≥2 prior transurethral procedures (p = 0.030), and a non-obliterated lumen (p = 0.020) were independent predictive factors for substitution urethroplasty. However, the recurrence rate (p = 0.18) did not significantly differ between the two groups. Conclusions: Proximal and distal BUS have substantially different anatomical characteristics and etiologies and require different reconstructive techniques.
目的:近端和远端球部尿道狭窄(BUS)具有不同的疾病特征,尽管被视为一种疾病,但需要不同的治疗策略。为了明确两者的区别,我们对数据库进行了分析,区分了两种类型的 BUS。方法我们回顾性审查了 2004 年 8 月至 2022 年 3 月期间在日本国防医学院接受尿道成形术的 196 例 BUS 患者的数据。我们根据狭窄段将患者分为近端组(第 1 组)和远端组(第 2 组),并比较了各组患者的背景和手术技术。我们使用多变量逻辑回归分析评估了狭窄段是否是替代尿道成形术选择的独立预测因素。复发率采用 Kaplan-Meier 法和对数秩检验进行计算和比较。结果显示与第 2 组相比,第 1 组患者的管腔不淤塞率较低(73% 对 94%,P = 0.020),狭窄长度明显较短(10 mm 对 23 mm,P < 0.001),更多是由外部创伤引起(47% 对 26%,P = 0.010)。逻辑回归分析表明,狭窄段(远端)(p < 0.001)、狭窄长度(≥20 毫米)(p < 0.001)、先前经尿道手术≥2 次(p = 0.030)和管腔不通畅(p = 0.020)是替代尿道成形术的独立预测因素。然而,两组患者的复发率(p = 0.18)并无显著差异。结论:近端和远端 BUS 的解剖特点和病因大不相同,需要不同的重建技术。
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引用次数: 0
The “Spiked Helmet Sign”, a Mimic of ST-Elevation Myocardial Infarction in Post-Nephrectomy Ileus 尖盔征 "是肾切除术后回肠梗死 ST 段抬高心肌梗死的模拟征象
Pub Date : 2024-04-04 DOI: 10.3390/siuj5020015
J. Wynn, Jonathan McCafferty, Robert Forsyth
There are many causes of ST-elevation on electrocardiogram (ECG). ECG changes in the setting of intra-abdominal pathology is a rare and under characterised and includes the “spiked helmet sign”. We report a rare case of the “spiked helmet sign” that presented with ST-elevation in the precordial leads due to post-operative ileus.
导致心电图(ECG)ST 段抬高的原因有很多。腹腔内病变引起的心电图变化非常罕见,而且特征不明显,其中包括 "尖盔征"。我们报告了一例罕见的 "尖盔征 "病例,该病例因术后回肠梗阻导致心前区导联出现 ST 段抬高。
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引用次数: 0
Robotic Precision vs. Human Dexterity—Benchtop Comparative Study of Free-Hand vs. Robotic-Assisted Puncture in Fluoroscopy-Guided Percutaneous Nephrolithotomy 机器人的精确性与人类的灵巧性--透视引导经皮肾镜取石术中徒手穿刺与机器人辅助穿刺的台式比较研究
Pub Date : 2024-02-19 DOI: 10.3390/siuj5010013
Jeffery Ze Kang Lim, C. C. Ann, A. Phyo, Kanesh Kumaran, Ahmad Nazran, S. Kuppusamy, Teng Aik Ong, W. Yeoh
Introduction: Percutaneous nephrolithotomy (PCNL) is the standard procedure for treating large kidney stones, especially those measuring over 20 mm or staghorn stones. Accurate placement of the tract into the renal collecting system of interest is crucial. Objective: To compare the free-hand puncture technique with robotic-assisted puncture during fluoroscopy-guided PCNL on a phantom kidney model in terms of efficiency and safety. A self-assessment of confidence levels after each puncture was recorded. Study Design: This prospective single-center benchtop study was conducted at the University Malaya Medical Centre (UMMC). Four urological residents participated and performed phantom punctures using both the free-hand bull’s eye technique and the automated needle targeting system with X-ray (ANT-X). Each resident performed a total of 60 punctures on the renal phantom models, with 30 punctures using the free-hand technique and 30 punctures using the ANT-X robotic-assisted system. Results: A total of 240 needle insertions were conducted, with 120 in the ANT-X group and 120 in the free-hand group. The success rate of needle insertions was 100% in both groups. However, the study revealed that the ANT-X group required, on average, an additional 51 s for needle puncture compared to the free-hand group (p < 0.001). In terms of fluoroscopic exposure, the ANT-X group exhibited significantly lower radiation exposure compared to the free-hand group (p < 0.001). Sub-analysis showed that puncture time remained consistent regardless of the technique used, but fluoroscopic screening time decreased with increasing participant experience. The ANT-X group also resulted in significantly lower radiation exposure during initial sessions compared to the free-hand technique. Surgeons’ self-assessment of confidence levels indicated a high level of confidence in needle puncture. Conclusions: Our benchtop study comparing the efficacy and safety between free-hand and ANT-X phantom punctures revealed comparable results. The needle puncture technique facilitated by the ANT-X system showed promising results in terms of reducing fluoroscopic exposure, albeit at the cost of longer operative times. This technology holds promise for novice surgeons who are in the early stages of their learning curve and might be useful for experienced surgeons looking to reduce radiation exposure.
导言:经皮肾镜取石术(PCNL)是治疗大块肾结石,尤其是超过 20 毫米的结石或鹿角状结石的标准手术。准确地将取石器置入相关的肾集合系统至关重要。目的比较在荧光透视引导下进行 PCNL 时,在假肾模型上采用徒手穿刺技术和机器人辅助穿刺技术的效率和安全性。记录每次穿刺后的信心水平自我评估。研究设计:这项前瞻性单中心台式研究在马来亚大学医学中心(UMMC)进行。四名泌尿科住院医师参与了这项研究,并使用自由手靶心技术和带 X 射线的自动针瞄准系统 (ANT-X) 进行了模型穿刺。每位住院医师在肾脏模型上共进行了 60 次穿刺,其中 30 次使用徒手穿刺技术,30 次使用 ANT-X 机器人辅助系统。结果共进行了 240 次穿刺,其中 ANT-X 组 120 次,徒手组 120 次。两组的插针成功率均为 100%。不过,研究显示,与徒手组相比,ANT-X 组的穿刺针穿刺时间平均延长了 51 秒(p < 0.001)。在透视暴露方面,ANT-X 组的辐射暴露明显低于徒手组(p < 0.001)。子分析表明,无论使用哪种技术,穿刺时间都保持一致,但透视筛查时间随着参与者经验的增加而减少。与徒手技术相比,ANT-X 组在初始疗程中的辐射量也明显较低。外科医生对信心水平的自我评估表明,他们对穿刺针穿刺有很高的信心。结论:我们的台式研究比较了徒手穿刺和 ANT-X 模拟穿刺的有效性和安全性,结果不相上下。ANT-X 系统辅助的穿刺针技术在减少透视暴露方面显示出良好的效果,尽管代价是手术时间延长。这项技术对于处于学习曲线早期阶段的外科医生来说是有希望的,对于希望减少辐射暴露的经验丰富的外科医生来说也是有用的。
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引用次数: 0
Ultrasound-Based Prognostic Anatomical Parameters for Post-Prostatectomy Incontinence: A Systematic Review 基于超声的前列腺切除术后尿失禁预后解剖参数:系统回顾
Pub Date : 2024-02-18 DOI: 10.3390/siuj5010012
Cecile T. Pham, Jordan E. Cohen, Manish I. Patel
Background: A number of assessment methods for the pelvic floor have been described. Male pelvic floor ultrasound is an accessible, noninvasive assessment tool. Objective: To evaluate current published literature on anatomical parameters on pre- and postoperative ultrasound imaging of the male pelvic floor and correlation with continence status following radical prostatectomy (RP). Methods: A comprehensive literature search was conducted using the PRISMA guidelines to identify publications up to November 2022. Exclusion criteria consisted of animal studies, non-English articles, case reports, reviews and abstracts or reports from conferences. A full-text review was performed on 12 papers using ultrasound to assess pelvic floor anatomy and correlation with continence status following RP. Results: A total of 18 anatomical parameters were evaluated using US. Membranous urethral length (MUL), striated urethral sphincter (SUS) morphology and activation were most commonly studied. Shorter pre- and postoperative MUL, decreased preoperative SUS thickness and vascularity, postoperative discontinuity of SUS muscle fibres and decreased SUS activation are associated with post-prostatectomy incontinence (PPI). There is a paucity of data comparing anatomical changes in men prior to and following RP. The benefits of transperineal ultrasound are that it is minimally invasive, accessible, provides dynamic imaging of all three striated muscle complexes simultaneously and includes a bony landmark to reference measures of pelvic floor muscle displacement. Conclusions: Ultrasound evaluation of the male pelvic floor is an evolving field as there is development in technology and understanding of pelvic floor anatomy. It is an accessible and dynamic imaging modality, which allows both morphological and functional assessment of pelvic floor anatomy and its role in PPI. MUL and SUS morphology and activation are associated with continence status following RP. Several other anatomical parameters that may predict PPI were identified. Current literature is limited by small, single-centre studies with heterogeneous cohorts and methodologies.
背景:盆底的评估方法有很多。男性盆底超声是一种方便、无创的评估工具。目的:评估目前已发表的有关男性盆底前后解剖参数的文献:评估目前已发表的关于男性盆底术前和术后超声成像解剖学参数以及与根治性前列腺切除术(RP)后尿失禁状况相关性的文献。方法:采用PRISMA指南进行了全面的文献检索,以确定截至2022年11月的出版物。排除标准包括动物研究、非英语文章、病例报告、综述和会议摘要或报告。对 12 篇使用超声波评估盆底解剖结构以及与 RP 术后尿失禁状况相关性的论文进行了全文综述。结果:共使用 US 评估了 18 个解剖参数。最常研究的是膜尿道长度(MUL)、横纹尿道括约肌(SUS)形态和激活情况。术前和术后 MUL 较短、术前 SUS 厚度和血管减少、术后 SUS 肌纤维中断和 SUS 活性降低与前列腺切除术后尿失禁(PPI)有关。比较男性在前列腺电切术前后的解剖学变化的数据很少。经会阴超声检查的优点是微创、方便、可同时对所有三块横纹肌复合体进行动态成像,并包含一个骨性地标,可作为盆底肌肉移位测量的参考。结论随着技术的发展和对盆底解剖的了解,男性盆底超声评估是一个不断发展的领域。它是一种便捷、动态的成像方式,可对盆底解剖结构及其在 PPI 中的作用进行形态和功能评估。MUL和SUS的形态和激活与RP术后的尿失禁状况有关。研究还发现了其他一些可预测 PPI 的解剖参数。目前的文献受到小型单中心研究的限制,这些研究的队列和方法不尽相同。
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引用次数: 0
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Société Internationale d’Urologie Journal
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