Pub Date : 2014-05-07DOI: 10.1109/MEPHOCO.2014.6866454
A. Garibbo, A. Palucci, R. Chirico
This paper deals with the presentation of the recent development of a stand-off laser Raman apparatus to monitor explosive traces dispersed on fabrics. The system has been designed to operate in compliance with the international eye-safe regulations and therefore to be installed, in the future, in public facilities check-points (e.g. mass transit check points). The particular high sensitivity reached in the detection of traces is due to the specific optical design and electro-optics components adopted. The sensor was successively, successfully integrated in a network of sensors (System of the Systems) and tested in a real environment (a Metro station in Paris).
{"title":"Raman scattering for explosive traces stand-off detection","authors":"A. Garibbo, A. Palucci, R. Chirico","doi":"10.1109/MEPHOCO.2014.6866454","DOIUrl":"https://doi.org/10.1109/MEPHOCO.2014.6866454","url":null,"abstract":"This paper deals with the presentation of the recent development of a stand-off laser Raman apparatus to monitor explosive traces dispersed on fabrics. The system has been designed to operate in compliance with the international eye-safe regulations and therefore to be installed, in the future, in public facilities check-points (e.g. mass transit check points). The particular high sensitivity reached in the detection of traces is due to the specific optical design and electro-optics components adopted. The sensor was successively, successfully integrated in a network of sensors (System of the Systems) and tested in a real environment (a Metro station in Paris).","PeriodicalId":219746,"journal":{"name":"2014 Third Mediterranean Photonics Conference","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115643962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2014-05-07DOI: 10.1109/MEPHOCO.2014.6866474
M. Baier, F. Soares, D. Melati, M. Achouche, D. Lanteri, F. Morichetti, A. Melloni, M. Moehrle, N. Grote
We present results on optical crosstalk in the photonic integration platform developed at Fraunhofer HHI. Two fundamental mechanisms are investigated: stray light generation at butt-joints and coupling between two passive waveguides. The latter can happen in two regimes: evanescently or radiatively, depending on the gap between the waveguides. Measurements show the amount of crosstalk that is to be expected on ASPICs. Moreover, means to reduce crosstalk levels that are compatible with the existing technology are demonstrated.
{"title":"Optical crosstalk on Rx/Tx photonic integration platform","authors":"M. Baier, F. Soares, D. Melati, M. Achouche, D. Lanteri, F. Morichetti, A. Melloni, M. Moehrle, N. Grote","doi":"10.1109/MEPHOCO.2014.6866474","DOIUrl":"https://doi.org/10.1109/MEPHOCO.2014.6866474","url":null,"abstract":"We present results on optical crosstalk in the photonic integration platform developed at Fraunhofer HHI. Two fundamental mechanisms are investigated: stray light generation at butt-joints and coupling between two passive waveguides. The latter can happen in two regimes: evanescently or radiatively, depending on the gap between the waveguides. Measurements show the amount of crosstalk that is to be expected on ASPICs. Moreover, means to reduce crosstalk levels that are compatible with the existing technology are demonstrated.","PeriodicalId":219746,"journal":{"name":"2014 Third Mediterranean Photonics Conference","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125319474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2014-05-07DOI: 10.1109/MEPHOCO.2014.6866466
M. Vanzi, G. Mura, G. Marcello
The non-unitary ideality factor of a MQW laser diode and its measurable threshold voltage are shown to be a puzzling question. The analysis is based on the predictions of the canonical rate equations, once they are translated into the device language, that replaces theoretical quantities as quasi-Fermi levels and carrier densities with measurable ones as voltage and currents. Trying the numerical fit of experimental curves, one is forced to go back to fundamentals of laser diode theory. The solution of the puzzle requires to reconsider points as fundamental as the meaning of locality of band-to-band transitions in quantum regions.
{"title":"Ideality factor and threshold voltage in laser diodes","authors":"M. Vanzi, G. Mura, G. Marcello","doi":"10.1109/MEPHOCO.2014.6866466","DOIUrl":"https://doi.org/10.1109/MEPHOCO.2014.6866466","url":null,"abstract":"The non-unitary ideality factor of a MQW laser diode and its measurable threshold voltage are shown to be a puzzling question. The analysis is based on the predictions of the canonical rate equations, once they are translated into the device language, that replaces theoretical quantities as quasi-Fermi levels and carrier densities with measurable ones as voltage and currents. Trying the numerical fit of experimental curves, one is forced to go back to fundamentals of laser diode theory. The solution of the puzzle requires to reconsider points as fundamental as the meaning of locality of band-to-band transitions in quantum regions.","PeriodicalId":219746,"journal":{"name":"2014 Third Mediterranean Photonics Conference","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125320738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2014-05-07DOI: 10.1109/MEPHOCO.2014.6866495
J. R. Fernandes, D. J. Passos, J. Xavier, J. Morais, O. Frazão
This work addresses the experimental work of characterization of wood (P. pinaster) bonded joints by means of pure mode I using the double cantilever beam (DCB) configuration test. The approach combines fracture mechanical testing with embedded fiber Bragg grating (FBG) sensors in the glue line. A method for the determination of the FBG reflection spectra shift based on the spectral geometric mean determination is used. The load-displacement (P-δ) curve and wavelength-displacement (λ-δ) curve are acquired and related to each other. An quantification of a global internal equivalent uniform strain applied to the FBG was then calculated.
{"title":"Initial studies of glued wood joints using FBG strain sensors","authors":"J. R. Fernandes, D. J. Passos, J. Xavier, J. Morais, O. Frazão","doi":"10.1109/MEPHOCO.2014.6866495","DOIUrl":"https://doi.org/10.1109/MEPHOCO.2014.6866495","url":null,"abstract":"This work addresses the experimental work of characterization of wood (P. pinaster) bonded joints by means of pure mode I using the double cantilever beam (DCB) configuration test. The approach combines fracture mechanical testing with embedded fiber Bragg grating (FBG) sensors in the glue line. A method for the determination of the FBG reflection spectra shift based on the spectral geometric mean determination is used. The load-displacement (P-δ) curve and wavelength-displacement (λ-δ) curve are acquired and related to each other. An quantification of a global internal equivalent uniform strain applied to the FBG was then calculated.","PeriodicalId":219746,"journal":{"name":"2014 Third Mediterranean Photonics Conference","volume":"327 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124609098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2014-05-07DOI: 10.1109/MEPHOCO.2014.6866464
G. Reed, G. Mashanovich, F. Gardes, D. Thomson, Y. Hu, J. Soler-Penadés, M. Nedeljkovic, A. Khokhar, P. Thomas, C. Littlejohns, A. Ahmed, S. Reynolds, R. Topley, C. Mitchell, S. Stankovic, P. Wilson, L. Ke, T. B. Ben Masaud, A. Tarazona, H. Chong
We discuss recent results in our work on Silicon Photonics. This includes both active and passive devices for a variety of applications. In particular we discuss work on wafer scale testing, modulators and drivers, device integration and mid-IR silicon photonics components. These devices are important both for established applications such as integrated transceivers for short reach interconnects, as well as emerging applications such as disposable sensors and mass market photonics.
{"title":"Silicon Photonic devices for the near- and the mid-infrared wavelength ranges","authors":"G. Reed, G. Mashanovich, F. Gardes, D. Thomson, Y. Hu, J. Soler-Penadés, M. Nedeljkovic, A. Khokhar, P. Thomas, C. Littlejohns, A. Ahmed, S. Reynolds, R. Topley, C. Mitchell, S. Stankovic, P. Wilson, L. Ke, T. B. Ben Masaud, A. Tarazona, H. Chong","doi":"10.1109/MEPHOCO.2014.6866464","DOIUrl":"https://doi.org/10.1109/MEPHOCO.2014.6866464","url":null,"abstract":"We discuss recent results in our work on Silicon Photonics. This includes both active and passive devices for a variety of applications. In particular we discuss work on wafer scale testing, modulators and drivers, device integration and mid-IR silicon photonics components. These devices are important both for established applications such as integrated transceivers for short reach interconnects, as well as emerging applications such as disposable sensors and mass market photonics.","PeriodicalId":219746,"journal":{"name":"2014 Third Mediterranean Photonics Conference","volume":"109 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117207229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2014-05-07DOI: 10.1109/MEPHOCO.2014.6866476
C. Rizza, E. Palange, A. Ciattoni
We investigate the electromagnetic response of a novel class of multi-layered metamaterials exhibiting one-dimensional mirror asymmetry. In the quasi-homogenized, we prove that the effect of mirror asymmetry yields a specific electromagnetic chiral response.
{"title":"Artificial electromagnetic chirality in multi-layered metamaterial structures","authors":"C. Rizza, E. Palange, A. Ciattoni","doi":"10.1109/MEPHOCO.2014.6866476","DOIUrl":"https://doi.org/10.1109/MEPHOCO.2014.6866476","url":null,"abstract":"We investigate the electromagnetic response of a novel class of multi-layered metamaterials exhibiting one-dimensional mirror asymmetry. In the quasi-homogenized, we prove that the effect of mirror asymmetry yields a specific electromagnetic chiral response.","PeriodicalId":219746,"journal":{"name":"2014 Third Mediterranean Photonics Conference","volume":"106 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123807914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2014-05-07DOI: 10.1109/MEPHOCO.2014.6866461
A. Iadicicco, M. Della Pietra, S. Campopiano
This work is devoted to a feasibility analysis of the use of Fiber Bragg Grating (FBG) sensing technology for real-time deformation monitoring of a gaseous tracking particle detector. Our attention is focused on a micromegas (an abbreviation for “micro mesh gaseous structure” (MM)), that is a micro pattern gas detector to be applied in Large Hadron Collider (LHC) at European Organization for Nuclear Research (CERN) in the ATLAS experiment. One mandatory issue for the correct operation of the MM detector is a precise monitoring of its panels' flatness/deformation. To this aim, FBG real-time sensing technology is proposed for its capability to meet important requirements in terms of radiation hardness and insensitivity to magnetic fields and to offer local strain detection with high sensitivity (resolution of 1 με). As a demonstrative target, in this work some FBG sensors have been integrated (surface attached) with a miniature MM detector support panel in order to investigate their potentialities/capabilities in detecting local strain and thus bending. The obtained experimental results confirm that FBG sensors, that tolerate high radiation, are able to monitor deformation and curvature in accord with high energy physics requirements.
本文研究了光纤布拉格光栅(FBG)传感技术用于气体跟踪粒子探测器实时变形监测的可行性分析。我们关注的是一种微型气体探测器(micro - megas，即“微网状气体结构”(micro mesh gas structure, MM)的缩写)，它是一种用于欧洲核子研究组织(CERN)大型强子对撞机(LHC) ATLAS实验的微型模式气体探测器。MM探测器正确操作的一个必要问题是精确监测其面板的平整度/变形。为此，提出了光纤光栅实时传感技术，因为它能够满足辐射硬度和对磁场不敏感的重要要求，并提供高灵敏度(分辨率为1 με)的局部应变检测。作为一个示范目标，在这项工作中，一些FBG传感器已经集成(表面附着)与微型MM探测器支撑面板，以研究它们在检测局部应变和弯曲方面的潜力/能力。实验结果表明，承受高辐射的光纤光栅传感器能够监测形变和曲率，符合高能物理要求。
{"title":"Fiber Bragg Grating strain sensors for tracking particle detector","authors":"A. Iadicicco, M. Della Pietra, S. Campopiano","doi":"10.1109/MEPHOCO.2014.6866461","DOIUrl":"https://doi.org/10.1109/MEPHOCO.2014.6866461","url":null,"abstract":"This work is devoted to a feasibility analysis of the use of Fiber Bragg Grating (FBG) sensing technology for real-time deformation monitoring of a gaseous tracking particle detector. Our attention is focused on a micromegas (an abbreviation for “micro mesh gaseous structure” (MM)), that is a micro pattern gas detector to be applied in Large Hadron Collider (LHC) at European Organization for Nuclear Research (CERN) in the ATLAS experiment. One mandatory issue for the correct operation of the MM detector is a precise monitoring of its panels' flatness/deformation. To this aim, FBG real-time sensing technology is proposed for its capability to meet important requirements in terms of radiation hardness and insensitivity to magnetic fields and to offer local strain detection with high sensitivity (resolution of 1 με). As a demonstrative target, in this work some FBG sensors have been integrated (surface attached) with a miniature MM detector support panel in order to investigate their potentialities/capabilities in detecting local strain and thus bending. The obtained experimental results confirm that FBG sensors, that tolerate high radiation, are able to monitor deformation and curvature in accord with high energy physics requirements.","PeriodicalId":219746,"journal":{"name":"2014 Third Mediterranean Photonics Conference","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128233830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2014-05-07DOI: 10.1109/MEPHOCO.2014.6866465
A. Bensoussan
From optoelectronics commercial systems through aerospace applications, new technologies based equipment must be designed taking into account reliability risks. Existing qualification standards and processes have been developed from field return “lessons learned”. The qualification methods have been built-up to take into account questions and concerns observed on previous well established processes. Is this approach applicable to new products and materials? How will new optoelectronic technologies, nanotechnologies, and new packaging techniques perform when tested under conditions defined in existing standards? Are the Aerospace and Military standards adequate to validate long term application and proof of reliability for the new devices? What is missing, and what is needed? Should we modify the methodology for qualifying new parts based on these innovative technologies? What is needed for implementing efficiently and just in time High Reliability application processes? Evolving methodology may be one solution but must be constructed based on results of experiments from FOAT (Failure Oriented Accelerated Testing) and QT (Qualification Testing) for new technologies. This presentation gives an overview of general issues of microelectronics when employed in harsh environments (electrical, optical, thermal, mechanical, radiation). Understanding the need, defining goals, accumulating field failure data, developing reliability models and educating our customers is a recommended approach to develop comprehensive FOAT and QT programs.
{"title":"Qualification and reliability standards for photonic component technologies","authors":"A. Bensoussan","doi":"10.1109/MEPHOCO.2014.6866465","DOIUrl":"https://doi.org/10.1109/MEPHOCO.2014.6866465","url":null,"abstract":"From optoelectronics commercial systems through aerospace applications, new technologies based equipment must be designed taking into account reliability risks. Existing qualification standards and processes have been developed from field return “lessons learned”. The qualification methods have been built-up to take into account questions and concerns observed on previous well established processes. Is this approach applicable to new products and materials? How will new optoelectronic technologies, nanotechnologies, and new packaging techniques perform when tested under conditions defined in existing standards? Are the Aerospace and Military standards adequate to validate long term application and proof of reliability for the new devices? What is missing, and what is needed? Should we modify the methodology for qualifying new parts based on these innovative technologies? What is needed for implementing efficiently and just in time High Reliability application processes? Evolving methodology may be one solution but must be constructed based on results of experiments from FOAT (Failure Oriented Accelerated Testing) and QT (Qualification Testing) for new technologies. This presentation gives an overview of general issues of microelectronics when employed in harsh environments (electrical, optical, thermal, mechanical, radiation). Understanding the need, defining goals, accumulating field failure data, developing reliability models and educating our customers is a recommended approach to develop comprehensive FOAT and QT programs.","PeriodicalId":219746,"journal":{"name":"2014 Third Mediterranean Photonics Conference","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130674933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2014-05-07DOI: 10.1109/MEPHOCO.2014.6866471
M. Grande, M. Vincenti, T. Stomeo, G. Bianco, D. de Ceglia, V. Petruzzelli, G. Bruno, M. de Vittorio, M. Scalora, A. D’orazio
We investigate the linear and nonlinear properties of a monolayer graphene embedded in a quarter-wave one-dimensional Photonic Crystal (1D-PhC) in terms of absorption and losses. In particular, we show that it is possible to achieve near-perfect narrow-band absorption when the monolayer graphene is sandwiched between two PhC mirrors with optimized pair number. The simulations reveal that the resonant wavelength and the total absorption frequency may be tuned by tilting the angle of incidence of the impinging source for both TE and TM polarizations. We also show that the losses related to the dielectric materials constituting the 1D-PhC can degrade the optical performance of the device. Preliminary fabrication tests reveal that the sputtering process does not lead to graphene structural damages affecting the material properties. Finally, by exploiting the large nonlinear response and the saturation effects of graphene monolayers we demonstrate how the structure can be dynamically change the structure from a perfect absorber to a mirror. These features make this device attractive for different applications ranging from tunable and saturable absorbers for short-pulse lasers, to graphene-based photodetectors.
{"title":"Absorption and losses in one-dimensional photonic crystal perfect absorber incorporating a monolayer graphene","authors":"M. Grande, M. Vincenti, T. Stomeo, G. Bianco, D. de Ceglia, V. Petruzzelli, G. Bruno, M. de Vittorio, M. Scalora, A. D’orazio","doi":"10.1109/MEPHOCO.2014.6866471","DOIUrl":"https://doi.org/10.1109/MEPHOCO.2014.6866471","url":null,"abstract":"We investigate the linear and nonlinear properties of a monolayer graphene embedded in a quarter-wave one-dimensional Photonic Crystal (1D-PhC) in terms of absorption and losses. In particular, we show that it is possible to achieve near-perfect narrow-band absorption when the monolayer graphene is sandwiched between two PhC mirrors with optimized pair number. The simulations reveal that the resonant wavelength and the total absorption frequency may be tuned by tilting the angle of incidence of the impinging source for both TE and TM polarizations. We also show that the losses related to the dielectric materials constituting the 1D-PhC can degrade the optical performance of the device. Preliminary fabrication tests reveal that the sputtering process does not lead to graphene structural damages affecting the material properties. Finally, by exploiting the large nonlinear response and the saturation effects of graphene monolayers we demonstrate how the structure can be dynamically change the structure from a perfect absorber to a mirror. These features make this device attractive for different applications ranging from tunable and saturable absorbers for short-pulse lasers, to graphene-based photodetectors.","PeriodicalId":219746,"journal":{"name":"2014 Third Mediterranean Photonics Conference","volume":"34 3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125992580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2014-05-07DOI: 10.1109/MEPHOCO.2014.6866462
B. Della Ventura, R. Funari, C. Altucci, R. Velotta
Photonic Immobilization Technique (PIT) is a novel approach to the functionalization of gold surface that results in antibodies spatially oriented with their variable part side-up. The effectiveness of PIT has been applied to the gold electrode of a Quartz-Crystal-Microbalance (QCM) for the detection of both heavy and light molecules. In the latter case we are able to immobilize the antibody against the parathion (a toxic pesticide with M≈300 Da) setting up a protocol to make the antigen heavier through the complexion with much heavier proteins (Bovine Serum Albumine, BSA). The whole analysis requires 10 minutes and a lower limit of detection (LOD) as low as 4 ppb in water is demonstrated. Given the versatility and robustness of QCM our technique could represent a breakthrough in the realization of easy-to-use, cost effectiveness immunosensors.
{"title":"UV-light-assisted functionalization of Quartz-Crystal-Microbalance","authors":"B. Della Ventura, R. Funari, C. Altucci, R. Velotta","doi":"10.1109/MEPHOCO.2014.6866462","DOIUrl":"https://doi.org/10.1109/MEPHOCO.2014.6866462","url":null,"abstract":"Photonic Immobilization Technique (PIT) is a novel approach to the functionalization of gold surface that results in antibodies spatially oriented with their variable part side-up. The effectiveness of PIT has been applied to the gold electrode of a Quartz-Crystal-Microbalance (QCM) for the detection of both heavy and light molecules. In the latter case we are able to immobilize the antibody against the parathion (a toxic pesticide with M≈300 Da) setting up a protocol to make the antigen heavier through the complexion with much heavier proteins (Bovine Serum Albumine, BSA). The whole analysis requires 10 minutes and a lower limit of detection (LOD) as low as 4 ppb in water is demonstrated. Given the versatility and robustness of QCM our technique could represent a breakthrough in the realization of easy-to-use, cost effectiveness immunosensors.","PeriodicalId":219746,"journal":{"name":"2014 Third Mediterranean Photonics Conference","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126123330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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