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Multiply robust estimation for average treatment effect among treated 对受治疗者的平均治疗效果进行稳健的乘法估计
IF 0.5 Q3 STATISTICS & PROBABILITY Pub Date : 2023-12-15 DOI: 10.1080/24754269.2023.2293554
Lu Wang, Peisong Han
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引用次数: 0
Communication-efficient distributed statistical inference on zero-inflated Poisson models 零膨胀泊松模型的高效通信分布统计推断
Q3 STATISTICS & PROBABILITY Pub Date : 2023-10-30 DOI: 10.1080/24754269.2023.2263721
Ran Wan, Yang Bai
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引用次数: 0
FragmGAN: generative adversarial nets for fragmentary data imputation and prediction FragmGAN:用于片段数据输入和预测的生成对抗网络
Q3 STATISTICS & PROBABILITY Pub Date : 2023-10-27 DOI: 10.1080/24754269.2023.2272554
Fang Fang, Shenliao Bao
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引用次数: 0
Log-rank and stratified log-rank tests Log-rank和分层Log-rank检验
Q3 STATISTICS & PROBABILITY Pub Date : 2023-10-05 DOI: 10.1080/24754269.2023.2263720
Ting Ye, Jun Shao, Yanyao Yi
In randomized clinical trials with right-censored time-to-event outcomes, the popular log-rank test without adjusting for baseline covariates is asymptotically valid for treatment effect under simple randomization of treatments but is too conservative under covariate-adaptive randomization. The stratified log-rank test, which adjusts baseline covariates in the test procedure by stratification, is asymptotically valid regardless of what treatment randomization is applied. In the literature, however, under simple randomization there is no affirmative conclusion about whether the stratified log-rank test is asymptotically more powerful than the unstratified log-rank test. In this article we show when the stratified and unstratified log-rank tests aim for the same null hypothesis and that, under simple randomization, the stratified log-rank test is asymptotically more powerful than the unstratified log-rank test in the region of alternative hypothesis that is specified by a Cox proportional hazards model. We also provide some discussion about why we do not have an affirmative conclusion in general.
在具有右审查事件发生时间结果的随机临床试验中,未调整基线协变量的流行对数秩检验在治疗的简单随机化下对治疗效果渐近有效,但在协变量自适应随机化下过于保守。分层对数秩检验通过分层来调整检验过程中的基线协变量,无论采用何种随机化治疗,该检验都是渐近有效的。然而,在文献中,在简单随机化的情况下,没有关于分层对数秩检验是否渐近地比非分层对数秩检验更有效的肯定结论。在本文中,我们展示了当分层和非分层log-rank检验针对相同的零假设时,在简单随机化下,分层log-rank检验在由Cox比例风险模型指定的可选假设区域内渐近地比非分层log-rank检验更强大。我们也提供了一些讨论,为什么我们没有一个肯定的结论一般。
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引用次数: 0
Autoregressive moving average model for matrix time series 矩阵时间序列的自回归移动平均模型
Q3 STATISTICS & PROBABILITY Pub Date : 2023-10-04 DOI: 10.1080/24754269.2023.2262360
Shujin Wu, Ping Bi
In the paper, the autoregressive moving average model for matrix time series (MARMA) is investigated. The properties of the MARMA model are investigated by using the conditional least square estimation, the conditional maximum likelihood estimation, the projection theorem in Hilbert space and the decomposition technique of time series, which include necessary and sufficient conditions for stationarity and invertibility, model parameter estimation, model testing and model forecasting.
研究了矩阵时间序列的自回归移动平均模型(MARMA)。利用条件最小二乘估计、条件极大似然估计、Hilbert空间投影定理和时间序列分解技术研究了MARMA模型的性质,包括平稳性和可逆性的充分必要条件、模型参数估计、模型检验和模型预测。
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引用次数: 0
Robust analyzes for longitudinal clinical trials with missing and non-normal continuous outcomes 对缺失和非正常连续结果的纵向临床试验进行稳健分析
Q3 STATISTICS & PROBABILITY Pub Date : 2023-09-26 DOI: 10.1080/24754269.2023.2261351
Siyi Liu, Yilong Zhang, Gregory T. Golm, Guanghan (Frank) Liu, Shu Yang
Missing data is unavoidable in longitudinal clinical trials, and outcomes are not always normally distributed. In the presence of outliers or heavy-tailed distributions, the conventional multiple imputation with the mixed model with repeated measures analysis of the average treatment effect (ATE) based on the multivariate normal assumption may produce bias and power loss. Control-based imputation (CBI) is an approach for evaluating the treatment effect under the assumption that participants in both the test and control groups with missing outcome data have a similar outcome profile as those with an identical history in the control group. We develop a robust framework to handle non-normal outcomes under CBI without imposing any parametric modeling assumptions. Under the proposed framework, sequential weighted robust regressions are applied to protect the constructed imputation model against non-normality in the covariates and the response variables. Accompanied by the subsequent mean imputation and robust model analysis, the resulting ATE estimator has good theoretical properties in terms of consistency and asymptotic normality. Moreover, our proposed method guarantees the analysis model robustness of the ATE estimation in the sense that its asymptotic results remain intact even when the analysis model is misspecified. The superiority of the proposed robust method is demonstrated by comprehensive simulation studies and an AIDS clinical trial data application.
在纵向临床试验中,数据缺失是不可避免的,而且结果并不总是正态分布的。在存在异常值或重尾分布的情况下,基于多元正态假设的混合模型和重复测量分析平均处理效果(ATE)的传统多重拟合可能会产生偏差和功率损失。基于对照的归算(control -based imputation, CBI)是一种评估治疗效果的方法,假设缺失结果数据的试验组和对照组的参与者与对照组中具有相同病史的参与者具有相似的结果概况。我们开发了一个鲁棒框架来处理CBI下的非正态结果,而不强加任何参数化建模假设。在该框架下,采用顺序加权鲁棒回归来保护构建的imputation模型免受协变量和响应变量的非正态性影响。伴随着随后的均值imputation和鲁棒模型分析,所得的ATE估计量在一致性和渐近正态性方面具有良好的理论性质。此外,我们提出的方法保证了分析模型的稳健性,即即使分析模型被错误指定,其渐近结果也保持完整。综合仿真研究和艾滋病临床试验数据的应用证明了所提出的鲁棒方法的优越性。
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引用次数: 1
Compression schemes for concept classes induced by three types of discrete undirected graphical models 由三种离散无向图形模型导出的概念类压缩方案
Q3 STATISTICS & PROBABILITY Pub Date : 2023-09-26 DOI: 10.1080/24754269.2023.2260046
Tingting Luo, Benchong Li
Sample compression schemes were first proposed by Littlestone and Warmuth in 1986. Undirected graphical model is a powerful tool for classification in statistical learning. In this paper, we consider labelled compression schemes for concept classes induced by discrete undirected graphical models. For the undirected graph of two vertices with no edge, where one vertex takes two values and the other vertex can take any finite number of values, we propose an algorithm to establish a labelled compression scheme of size VC dimension of associated concept class. Further, we extend the result to other two types of undirected graphical models and show the existence of labelled compression schemes of size VC dimension for induced concept classes. The work of this paper makes a step forward in solving sample compression problem for concept class induced by a general discrete undirected graphical model.
样本压缩方案最早是由Littlestone和Warmuth在1986年提出的。无向图模型是统计学习中分类的有力工具。本文考虑由离散无向图模型导出的概念类的标记压缩方案。针对无边的两个顶点无向图,其中一个顶点取两个值,另一个顶点取任意有限个值,提出了一种建立相关概念类的大小为VC维的标记压缩方案的算法。进一步,我们将结果推广到其他两种类型的无向图形模型,并证明了归纳概念类存在大小为VC维的标记压缩方案。本文的工作在解决由一般离散无向图模型引起的概念类的样本压缩问题上迈出了一步。
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引用次数: 0
Bayesian-inspired minimum contamination designs under a double-pair conditional effect model 双对条件效应模型下贝叶斯启发的最小污染设计
IF 0.5 Q3 STATISTICS & PROBABILITY Pub Date : 2023-08-30 DOI: 10.1080/24754269.2023.2250237
Ming-Chung Chang
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引用次数: 0
The study on systemic risk of rural finance based on macro–micro big data and machine learning 基于宏观-微观大数据和机器学习的农村金融系统性风险研究
IF 0.5 Q3 STATISTICS & PROBABILITY Pub Date : 2023-08-06 DOI: 10.1080/24754269.2023.2238975
Wanling Zhou, Sulin Pang, Zhiliang He
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引用次数: 0
Single-arm phase II three-outcome designs with handling of over-running/under-running 单臂II期三结局设计,处理过跑/过跑
IF 0.5 Q3 STATISTICS & PROBABILITY Pub Date : 2023-06-28 DOI: 10.1080/24754269.2023.2189348
W. Guo, Jianan Hui, Bob Zhong
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引用次数: 0
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