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Is there an Association between Side Effects of AstraZeneca, Sputnik, Covaxin and Sinopharm COVID-19 vaccines and Breakthrough Infections? 阿斯利康、Sputnik、Covaxin和国药新冠疫苗的副作用与突破性感染之间是否存在关联?
Pub Date : 2022-06-15 DOI: 10.18502/tbsrj.v4i2.9662
A. Abdollahi, I. Naseh, F. Kalroozi, M. H. Kazemi-Galougahi, M. Nezamzadeh, Mehran Frouzanian, Maryam Feyzollahi, Mojtaba Yousefi Zoshk
Introduction: Safe and efficacious vaccines against severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), would contribute to contain the COVID-19 pandemic. In this study, we examined this question that if there is an association between the incidence of side effects and the COVID-19 breakthrough infections. Material and Methods: This descriptive-analytical cross-sectional study was conducted for two months from June 22 to August 22, 2021. The study method was complete enumeration and 1474 healthcare workers who were medical staff of seven hospitals in Tehran and were vaccinated with one of the AstraZeneca, Covaxin, Sputnik V, and Sinopharm vaccines. Two main questions of this questionnaire were the occurrence or non-occurrence of any side effects after receiving the vaccines and the presence or absence of COVID-19 infection after vaccination. Results: According to the results obtained, in recipients vaccinated with Sinopharm vaccine, the group that reported at least one side effects after receiving the vaccine had a significantly higher COVID-19 infection than the group reported no side effects after vaccination (P<0.001) (RR=4.55). Also in whole sample study Participants who have reported one or more side effect after COVID-19 vaccination, had 3.7 times higher risk of breakthrough infection than others (P<0.001); However Among those vaccinated with AstraZeneca, Covaxin and Sputnik vaccines, no significant difference was observed between the groups with and without side effects after vaccination in terms of later COVID-19 infection. Conclusion: It seems that participants who have reported one or more side effect after COVID-19 vaccination, had times higher risk of breakthrough infection than others.
安全有效的严重急性呼吸综合征冠状病毒2 (SARS‐CoV‐2)疫苗将有助于控制COVID-19大流行。在这项研究中,我们研究了这样一个问题,即副作用的发生率与COVID-19突破性感染之间是否存在关联。材料和方法:本描述性分析横断面研究于2021年6月22日至8月22日进行,为期两个月。研究方法是对德黑兰7家医院的1474名医务人员进行完全枚举,接种了阿斯利康、科瓦新、Sputnik V和国药五种疫苗中的一种。该问卷的两个主要问题是接种疫苗后发生或不发生任何副作用以及接种疫苗后是否存在COVID-19感染。结果:结果显示,在接种国药疫苗的人群中,接种疫苗后至少有一种不良反应的人群感染COVID-19的比例明显高于接种疫苗后无不良反应的人群(P<0.001) (RR=4.55)。同样在全样本研究中,在COVID-19疫苗接种后报告一种或多种副作用的参与者,突破感染的风险是其他人的3.7倍(P<0.001);而在接种阿斯利康、Covaxin和Sputnik疫苗的人群中,接种后有副作用组和无副作用组之间的后续COVID-19感染无显著差异。结论:在COVID-19疫苗接种后报告了一种或多种副作用的参与者,其突破性感染的风险似乎是其他人的两倍。
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引用次数: 1
Effects of Adherence to the Principles of Professional Ethics on Nursing Performance: A Narrative Review Study 坚持职业道德原则对护理绩效的影响:一项叙述性回顾研究
Pub Date : 2022-06-15 DOI: 10.18502/tbsrj.v4i2.9664
Samira Golchin Mehr, Elahe Azami, Mahsa Kamali, H. Jafari
Introduction: Since the identification of priorities in planning can be decisive in reducing moral stress, this study aimed to review the impact of adherence to the principles of professional ethics on nursing performance reported in previous studies. Material and Methods: The search strategy in the present review was to screen the relevant studies published from the inception until 2020 on databases of PubMed/Medline, Web of science, CINAHL, Google Scholar, Magiran and SID, the results of which led to the extraction of 1785 related articles. After deleting duplicates and reviewing searched articles by researchers based on relevance, 27 articles were included in the study, 16 of which were excluded due to inaccessibility to the original articles and also writing in languages other than English and Persian. Eventually, 11 articles enrolled in the final analysis. Results: The studies emphasized four basic principles, including ''The effect of training on the development of ethical decision-making'', ''Understanding personnel and their response to ethical considerations'', ''Moral reasoning levels of personnel'', and ''Factors affecting the ethical decision- making of personnel''. Responsibility, improving the quality of patient care, and respect for the patient were the most important principles of professional ethics in nursing, whose full observance had been resulted in the reporting of favorable outcomes in studies. Conclusion: It seems that establishing a peaceful work environment can be effective in promoting adherence to professional ethics in various dimensions by nurses and in reporting misconduct in the workplace.
导言:由于确定计划中的优先事项对减少道德压力具有决定性作用,本研究旨在回顾以往研究中报道的遵守职业道德原则对护理绩效的影响。材料和方法:本综述的检索策略是筛选PubMed/Medline、Web of science、CINAHL、Google Scholar、Magiran和SID等数据库中自成立至2020年发表的相关研究,提取相关文章1785篇。在删除重复文章并根据相关性对研究人员搜索的文章进行审查后,27篇文章被纳入研究,其中16篇文章因无法获取原始文章以及使用英语和波斯语以外的语言而被排除在外。最终,11篇文章入选最终分析。结果:研究强调了“培训对伦理决策发展的影响”、“了解人员及其对伦理考虑的反应”、“人员的道德推理水平”和“影响人员伦理决策的因素”四个基本原则。责任、提高患者护理质量和尊重患者是护理职业道德最重要的原则,充分遵守这些原则导致了研究中良好结果的报告。结论:建立一个和平的工作环境似乎可以有效地促进护士在各个方面遵守职业道德,并报告工作场所的不当行为。
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引用次数: 0
Employing People to accompany the Patient to reduce Anxiety in the Operating Room 在手术室中雇人陪护,减少病人的焦虑
Pub Date : 2022-02-22 DOI: 10.18502/tbsrj.v4i1.8804
Seyyed Muhammad Mahdi Mahdavinoor, M. Rafiei
The article's abstract is not available.
这篇文章的摘要没有。
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引用次数: 0
Evaluation of Golden Proportion in Maxillary Anterior Teeth in Students of Mazandaran University of Medical Sciences in 2020 -2021 马赞达兰医科大学2020 -2021年度学生上颌前牙黄金比例评估
Pub Date : 2022-02-21 DOI: 10.18502/tbsrj.v4i1.8770
Kosar Dadgar, Mohammad Ebrahimisaravi, T. Molania, Jamshid Yazdani Charati, Nadia Jafari
Introduction: Some dentists use the golden ratio to balance the dimensions of the teeth and create a harmonious transverse ratio when reconstructing the maxillary anterior teeth. The aim of this study was to evaluate the presence of golden ratio in the visible width of maxillary anterior teeth in students of Mazandaran University of Medical Sciences. Material and Methods: In this cross-sectional descriptive-analytical study, 100 students (average age of 22 years) were selected from Mazandaran University of Medical Sciences whose anterior maxillary teeth met the inclusion criteria. Photographs of the teeth in normal position of head and social smile were taken from a distance of 30 cm. The apparent width of teeth was measured with a digital ruler. Kolmogorov-Smirnov test was used to evaluate the normal distribution of data, independent t-test was used to compare the width of anterior teeth and t-1 test was used to evaluate the golden ratio in transverse ratio of teeth. Data were analyzed using SPSS 24 software. Results: Measurements showed that the visible width of maxillary anterior teeth on the right and left as well as between men and women was not significantly different. Golden ratio was only established between the visible width of the right lateral to the right central teeth (P<0.05). Conclusion: The golden ratio was not established between any of the teeth, except for the right central to the right lateral. Therefore, the golden ratio cannot be a permanent criterion for the reconstruction of maxillary anterior teeth.
一些牙医在重建上颌前牙时,利用黄金比例来平衡牙齿的尺寸,创造一个和谐的横向比例。本研究的目的是评估马赞达兰医科大学学生上颌前牙可见宽度是否存在黄金分割。材料与方法:在本横断面描述性分析研究中,选取了100名上颌前牙符合纳入标准的Mazandaran医科大学学生(平均年龄22岁)。在30厘米的距离上拍摄正常头部位置和社交微笑的牙齿照片。用数字尺测量牙齿的表观宽度。采用Kolmogorov-Smirnov检验评价数据的正态分布,采用独立t检验比较前牙宽度,采用t-1检验评价牙横比中的黄金比例。数据分析采用SPSS 24软件。结果:测量结果显示,男女上下上颌前牙的可见宽度无明显差异。仅右侧中牙与右侧侧牙可见宽度之间存在黄金比例(P<0.05)。结论:除右中牙与右外侧牙外,其余牙间均未形成黄金分割比例。因此,黄金比例不能作为上颌前牙重建的永久标准。
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引用次数: 0
A Review on the Co-infection of HIV and Parasitic Diseases HIV与寄生虫病合并感染研究进展
Pub Date : 2022-02-21 DOI: 10.18502/tbsrj.v4i1.8775
H. Mohammadi, Mahdi Shooraj, Y. Ehteshaminia, S. Mahdavi
Introduction: The human immunodeficiency virus (HIV) and its associated disease, acquired immunodeficiency syndrome (AIDS), have become a global epidemic today. Approximately, 38 million people worldwide who are living with HIV are exposed to a variety of opportunistic infections. Opportunistic infections, continue to be a major cause of death among HIV-positive people. The high prevalence of specific opportunistic parasites among HIV-positive individuals is well known. These types of parasitic infections occur in HIV-positive individuals with more severe symptoms which are difficult to treatment. Material and Methods: In this study, the databases of PubMed, Scopus, SID, Magiran, Web of Science, IranDoc and Google Scholar were searched and articles related to the title from 2002 to 2021 were reviewed. Results: Toxoplasmic encephalitis is the most common cause of focal brain lesions due to opportunistic infections complicating the course of AIDS. In tropical countries, the pathophysiological, clinical, and epidemiological interactions between HIV and pathogenic organisms such as malaria are a major public health concern. About 11.2% of people living with HIV also have Cryptosporidium. Visceral leishmaniasis can accelerate the progression of the disease in HIV-positive individuals and leads to AIDS. Conclusion: Due to the resistance of Co-infection of HIV and parasitic diseases to treatment, the best solution seems to be HIV prevention, medical and health care for HIV-positive individuals. HIV prevention strategies include screening, use of protective equipment during sexual intercourse, non-use of shared syringes, treatment as prevention, post-exposure prevention and pre-virus prevention.
导读:人类免疫缺陷病毒(HIV)及其相关疾病,获得性免疫缺陷综合症(AIDS),今天已经成为一种全球性流行病。全世界约有3800万艾滋病毒感染者面临各种机会性感染。机会性感染仍然是艾滋病毒阳性者死亡的一个主要原因。艾滋病毒阳性个体中特定机会性寄生虫的高流行率是众所周知的。这些类型的寄生虫感染发生在艾滋病毒阳性个体中,症状较严重,难以治疗。材料与方法:检索PubMed、Scopus、SID、Magiran、Web of Science、IranDoc、b谷歌Scholar等数据库,检索2002 - 2021年与该题目相关的文章。结果:弓形虫性脑炎是艾滋病并发机会性感染引起局灶性脑损伤的最常见原因。在热带国家,艾滋病毒与疟疾等致病生物之间的病理生理、临床和流行病学相互作用是一个主要的公共卫生问题。约11.2%的艾滋病毒感染者同时携带隐孢子虫。内脏利什曼病可加速艾滋病毒阳性个体的疾病进展,并导致艾滋病。结论:由于HIV和寄生虫病合并感染对治疗的耐药性,对HIV阳性个体进行HIV预防和医疗保健似乎是最佳的解决方案。艾滋病毒预防战略包括筛查、在性交时使用防护设备、不使用共用注射器、治疗预防、接触后预防和病毒前预防。
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引用次数: 0
Prevalence of Acute Pancreatitis in Hospitalized Children with Renal Disease: A Five-Year Study 住院肾病患儿急性胰腺炎患病率:一项为期五年的研究
Pub Date : 2022-02-21 DOI: 10.18502/tbsrj.v4i1.8774
Seyed Massoud Mir Moeini, M. Sadeghian, Shahin Habibzadeh
Introduction: The aim of this study was to evaluate the characteristics and prognosis of acute pancreatitis in children with kidney disease in Ali Asghar Hospital between 2016 and 2020. Material and Methods: In this retrospective cross-sectional descriptive study, children with kidney disease who developed acute pancreatitis between 2016 and 2020 were studied. All patients with kidney disease who were hospitalized in the kidney ward of Ali Asghar Hospital were retrospectively evaluated and patients with acute pancreatitis were included in the study. Data analysis was performed using SPSS statistical software version 26 and for quantitative variables mean and standard deviation and for qualitative variables absolute frequency and percentage were recorded. Results: Finally, 12 patients with kidney disease who had acute pancreatitis. The mean age of the 12 participants was 9.05 ± 4.27 years. The mean duration of kidney disease was 5.7 ± 3.52 years. Four patients (33.3%) had a history of pre-pancreatitis infection. Three patients (25%) had nephrotic syndrome. Seven patients (58.3%) had ESRD. Nine patients (75%) were on dialysis. Conclusion: During the five-year period, only 12 cases of acute pancreatitis with a history of kidney disease were observed, none of which had a positive family history, and eventually all survived. Three-quarters of the cases also received dialysis treatment, and all cases presented with a clinical presentation of abdominal pain at first.
前言:本研究的目的是评估2016 - 2020年Ali Asghar医院肾病患儿急性胰腺炎的特点和预后。材料和方法:在这项回顾性横断面描述性研究中,研究了2016年至2020年间发生急性胰腺炎的肾脏疾病儿童。回顾性评估所有在Ali Asghar医院肾脏病房住院的肾脏疾病患者,并将急性胰腺炎患者纳入研究。采用SPSS统计软件26进行数据分析,定量变量记录均值和标准差,定性变量记录绝对频率和绝对百分比。结果:12例肾脏疾病合并急性胰腺炎。12名参与者的平均年龄为9.05±4.27岁。肾脏疾病的平均病程为5.7±3.52年。4例患者(33.3%)有胰腺炎前感染史。3例(25%)患者有肾病综合征。7例(58.3%)发生ESRD。9例(75%)患者接受透析治疗。结论:5年期间,仅观察到12例合并肾脏疾病史的急性胰腺炎患者,均无阳性家族史,最终全部存活。四分之三的病例也接受了透析治疗,所有病例的临床表现均为腹痛。
{"title":"Prevalence of Acute Pancreatitis in Hospitalized Children with Renal Disease: A Five-Year Study","authors":"Seyed Massoud Mir Moeini, M. Sadeghian, Shahin Habibzadeh","doi":"10.18502/tbsrj.v4i1.8774","DOIUrl":"https://doi.org/10.18502/tbsrj.v4i1.8774","url":null,"abstract":"Introduction: The aim of this study was to evaluate the characteristics and prognosis of acute pancreatitis in children with kidney disease in Ali Asghar Hospital between 2016 and 2020. \u0000Material and Methods: In this retrospective cross-sectional descriptive study, children with kidney disease who developed acute pancreatitis between 2016 and 2020 were studied. All patients with kidney disease who were hospitalized in the kidney ward of Ali Asghar Hospital were retrospectively evaluated and patients with acute pancreatitis were included in the study. Data analysis was performed using SPSS statistical software version 26 and for quantitative variables mean and standard deviation and for qualitative variables absolute frequency and percentage were recorded. \u0000Results: Finally, 12 patients with kidney disease who had acute pancreatitis. The mean age of the 12 participants was 9.05 ± 4.27 years. The mean duration of kidney disease was 5.7 ± 3.52 years. Four patients (33.3%) had a history of pre-pancreatitis infection. Three patients (25%) had nephrotic syndrome. Seven patients (58.3%) had ESRD. Nine patients (75%) were on dialysis. \u0000Conclusion: During the five-year period, only 12 cases of acute pancreatitis with a history of kidney disease were observed, none of which had a positive family history, and eventually all survived. Three-quarters of the cases also received dialysis treatment, and all cases presented with a clinical presentation of abdominal pain at first.","PeriodicalId":22117,"journal":{"name":"Tabari Biomedical Student Research Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88071396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of a Formulation of Vanishing Cream Containing Wheat Germ Oil with Safe Preservation, and Measurement of Antioxidants in the Cream by a Rapid Method 一种安全保存的小麦胚芽油消失乳膏配方的研制及其抗氧化剂的快速测定
Pub Date : 2022-02-21 DOI: 10.18502/tbsrj.v4i1.8773
Seyed Morteza Robatjazi, Narges Goodarzi, H. Ettehadi, Samira Samadieh, M. Zeinoddini
Introduction: Wheat germ is a by-product of the wheat mill and contains 10 to 15% of the oil. The use of wheat germ oil in cosmetics is because this oil contains ceramide that prevents skin aging and can preserve the skin. Material and Methods: A vanishing oil in water (O/W) cream based on wheat germ oil was made and formulated. The antioxidants of the cream were extracted, and the best extraction conditions were obtained by the Taguchi method. Four factors of temperature, time, 2,2-diphenyl-1-picrylhydrazyl (DPPH), and round per minute (RPM) were investigated at three levels. To maintain consumer health, carcinogenic preservatives such as parabens were removed from the formulation, and a new composition of methylpropanediol, capryl glycol, and phenylpropanoldiol (OMP) was used in the formulation. At microbial testing, two standard strains of Staphylococcus aureus and Pseudomonas aeruginosa were selected as representative of gram-positive and gram-negative bacteria. The stability of the antioxidants of wheat germ oil in the cream structure was studied.  Results: In the extraction of the antioxidants from the cream structure, the highest impact was related to the DPPH factor (78%) and temperature (14%), respectively. A growth inhibition zone of 24mm diameter was observed for S. aureus and 16mm for P. aeruginosa. The wheat germ oil cream was completely stable at 37°C after 30 days. Conclusion: A vanishing herbal cream was formulated base on OMP composition with a very good antimicrobial activity. A rapid extraction and measurement method of the cream antioxidants was established and optimized based on DPPH.
小麦胚芽是小麦加工的副产品,含有10 - 15%的油。在化妆品中使用小麦胚芽油是因为这种油含有神经酰胺,可以防止皮肤老化,并能保护皮肤。材料与方法:以小麦胚芽油为主要原料,研制了水消油乳膏。采用田口法提取乳脂中的抗氧化剂,获得最佳提取条件。对温度、时间、2,2-二苯基-1-吡啶酰肼(DPPH)和每分钟转数(RPM)四个因素进行了三个水平的研究。为了维护消费者健康,从配方中去除了对羟基苯甲酸酯等致癌防腐剂,并在配方中使用了甲基丙二醇、卡普二醇和苯基丙二醇(OMP)的新组合物。在微生物检测中,选择金黄色葡萄球菌和铜绿假单胞菌两株标准菌株作为革兰氏阳性菌和革兰氏阴性菌的代表。研究了小麦胚芽油抗氧化剂在乳霜结构中的稳定性。结果:乳膏结构中抗氧化剂的提取受DPPH因子(78%)和温度(14%)的影响最大。金黄色葡萄球菌生长抑制区直径为24mm,铜绿假单胞菌生长抑制区直径为16mm。小麦胚芽油乳膏在37℃下放置30天后完全稳定。结论:制备了一种具有良好抗菌活性的中药消隐乳膏。建立了一种基于DPPH的乳膏抗氧化剂快速提取测定方法,并对其进行了优化。
{"title":"Development of a Formulation of Vanishing Cream Containing Wheat Germ Oil with Safe Preservation, and Measurement of Antioxidants in the Cream by a Rapid Method","authors":"Seyed Morteza Robatjazi, Narges Goodarzi, H. Ettehadi, Samira Samadieh, M. Zeinoddini","doi":"10.18502/tbsrj.v4i1.8773","DOIUrl":"https://doi.org/10.18502/tbsrj.v4i1.8773","url":null,"abstract":"Introduction: Wheat germ is a by-product of the wheat mill and contains 10 to 15% of the oil. The use of wheat germ oil in cosmetics is because this oil contains ceramide that prevents skin aging and can preserve the skin. \u0000Material and Methods: A vanishing oil in water (O/W) cream based on wheat germ oil was made and formulated. The antioxidants of the cream were extracted, and the best extraction conditions were obtained by the Taguchi method. Four factors of temperature, time, 2,2-diphenyl-1-picrylhydrazyl (DPPH), and round per minute (RPM) were investigated at three levels. To maintain consumer health, carcinogenic preservatives such as parabens were removed from the formulation, and a new composition of methylpropanediol, capryl glycol, and phenylpropanoldiol (OMP) was used in the formulation. At microbial testing, two standard strains of Staphylococcus aureus and Pseudomonas aeruginosa were selected as representative of gram-positive and gram-negative bacteria. The stability of the antioxidants of wheat germ oil in the cream structure was studied. \u0000 Results: In the extraction of the antioxidants from the cream structure, the highest impact was related to the DPPH factor (78%) and temperature (14%), respectively. A growth inhibition zone of 24mm diameter was observed for S. aureus and 16mm for P. aeruginosa. The wheat germ oil cream was completely stable at 37°C after 30 days. \u0000Conclusion: A vanishing herbal cream was formulated base on OMP composition with a very good antimicrobial activity. A rapid extraction and measurement method of the cream antioxidants was established and optimized based on DPPH.","PeriodicalId":22117,"journal":{"name":"Tabari Biomedical Student Research Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77112388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Uterocutaneous Fistula due to Uncontrolled Diabetes: A Case Report 未控制糖尿病所致子宫皮瘘1例
Pub Date : 2022-02-21 DOI: 10.18502/tbsrj.v4i1.8771
M. Zanganeh, M. Zanganeh, Mehran Moslemi Aghili, Zahra Jarayedi
Uterocutaneous fistula is a rare complication. Here we report a 31-year-old pregnant woman with a history of cesarean section and diabetes who came to our clinic with labor pains and reduced fetal mobility. Nine days after the cesarean section, she referred to us again with a complaint of bloody discharge in the surgical wound. With further examination, uterocutaneous fistula was diagnosed in this patient and due to infection at the surgical wound and inside the fistula, antibiotic treatment was put on the agenda. This report shows the importance of the cause, diagnosis, and management of this complication.
子宫皮瘘是一种罕见的并发症。这里我们报告一位31岁的孕妇,她有剖宫产和糖尿病的病史,她以阵痛和胎儿活动能力降低来到我们的诊所。剖宫产9天后,她再次来找我们,主诉手术伤口出血。经进一步检查,该患者被诊断为子宫皮瘘,由于手术伤口和瘘内感染,抗生素治疗被提上日程。本报告显示了这种并发症的病因、诊断和治疗的重要性。
{"title":"Uterocutaneous Fistula due to Uncontrolled Diabetes: A Case Report","authors":"M. Zanganeh, M. Zanganeh, Mehran Moslemi Aghili, Zahra Jarayedi","doi":"10.18502/tbsrj.v4i1.8771","DOIUrl":"https://doi.org/10.18502/tbsrj.v4i1.8771","url":null,"abstract":"Uterocutaneous fistula is a rare complication. Here we report a 31-year-old pregnant woman with a history of cesarean section and diabetes who came to our clinic with labor pains and reduced fetal mobility. Nine days after the cesarean section, she referred to us again with a complaint of bloody discharge in the surgical wound. With further examination, uterocutaneous fistula was diagnosed in this patient and due to infection at the surgical wound and inside the fistula, antibiotic treatment was put on the agenda. This report shows the importance of the cause, diagnosis, and management of this complication.","PeriodicalId":22117,"journal":{"name":"Tabari Biomedical Student Research Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85299790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of the Relationship between Vitamin D Deficiency and Atherogenic Factors in Diabetic Patients with Metabolic Syndrome 糖尿病代谢综合征患者维生素D缺乏与动脉粥样硬化因素关系的评价
Pub Date : 2021-11-23 DOI: 10.18502/tbsrj.v3i4.7794
Leila Akbarbaglu, Elham Nozari Mirarkolaei, Massoumeh Hotelchi, Abbas Khonakdar-Tarsi, Mahboobeh Ghanbari, Parisa Mohamadi
Introduction: Metabolic syndrome includes a range of disorders that increase the risk of cardiovascular disease and diabetes mellitus. In this study, we examined the serum level of vitamin D3 in diabetic individuals with metabolic syndrome compared with non-diabetic individuals without metabolic syndrome and the association of serum vitamin D3 levels with metabolic syndrome and atherogenic factor (LDL/HDL). Material and Methods: In a case-control study, we included 110 women with metabolic syndrome according to ATP III criteria and 127 healthy women as a control group. Serum concentration of total cholesterol, LDL-C, FBS, HDL-C and serum triglyceride determined by enzymatic method and colorimetric and, serum level 25-(OH) vitamin D determined by ELISA. Results: It was found that the two healthy and metabolic groups were significantly different in terms of total cholesterol levels, LDL and triglyceride levels, HDL, VLDL, FBS, atherogenic index (LDL/HDL) and vitamin D levels (p<0.05). All participants in the control group and the patient and the whole study population were divided into two categories of insufficient and sufficient based on their measured serum concentrations of 25-(OH) vitamin D. There was a significant difference between the group with insufficient levels of vitamin D in comparison with the group with sufficient levels of vitamin D in terms of total cholesterol, LDL and triglyceride levels, HDL, VLDL, FBS and atherogenic index (LDL/HDL) (p=0.000). Conclusion: The present results showed that there is a significant relationship between level 25-(OH) D and atherogenic index (LDL/HDL) and the incidence of metabolic syndrome.
导言:代谢综合征包括一系列可增加心血管疾病和糖尿病风险的疾病。在这项研究中,我们检测了伴有代谢综合征的糖尿病患者与无代谢综合征的非糖尿病患者的血清维生素D3水平,以及血清维生素D3水平与代谢综合征和动脉粥样硬化因子(LDL/HDL)的关系。材料和方法:在一项病例对照研究中,我们纳入了110名根据ATP III标准患有代谢综合征的女性和127名健康女性作为对照组。酶法和比色法测定血清总胆固醇、LDL-C、FBS、HDL-C和血清甘油三酯浓度,ELISA法测定血清25-(OH)维生素D水平。结果:健康组和代谢组在总胆固醇水平、LDL和甘油三酯水平、HDL、VLDL、FBS、动脉粥样硬化指数(LDL/HDL)和维生素D水平上均有显著差异(p<0.05)。根据血清中25-(OH)维生素D的浓度,将对照组、患者和整个研究人群分为维生素D不足组和维生素D充足组。维生素D不足组与维生素D充足组在总胆固醇、LDL和甘油三酯水平、HDL、VLDL、FBS和动脉粥样硬化指数(LDL/HDL)方面存在显著差异(p=0.000)。结论:25-(OH) D水平与动脉粥样硬化指数(LDL/HDL)及代谢综合征发生率之间存在显著相关性。
{"title":"Evaluation of the Relationship between Vitamin D Deficiency and Atherogenic Factors in Diabetic Patients with Metabolic Syndrome","authors":"Leila Akbarbaglu, Elham Nozari Mirarkolaei, Massoumeh Hotelchi, Abbas Khonakdar-Tarsi, Mahboobeh Ghanbari, Parisa Mohamadi","doi":"10.18502/tbsrj.v3i4.7794","DOIUrl":"https://doi.org/10.18502/tbsrj.v3i4.7794","url":null,"abstract":"Introduction: Metabolic syndrome includes a range of disorders that increase the risk of cardiovascular disease and diabetes mellitus. In this study, we examined the serum level of vitamin D3 in diabetic individuals with metabolic syndrome compared with non-diabetic individuals without metabolic syndrome and the association of serum vitamin D3 levels with metabolic syndrome and atherogenic factor (LDL/HDL). \u0000Material and Methods: In a case-control study, we included 110 women with metabolic syndrome according to ATP III criteria and 127 healthy women as a control group. Serum concentration of total cholesterol, LDL-C, FBS, HDL-C and serum triglyceride determined by enzymatic method and colorimetric and, serum level 25-(OH) vitamin D determined by ELISA. \u0000Results: It was found that the two healthy and metabolic groups were significantly different in terms of total cholesterol levels, LDL and triglyceride levels, HDL, VLDL, FBS, atherogenic index (LDL/HDL) and vitamin D levels (p<0.05). All participants in the control group and the patient and the whole study population were divided into two categories of insufficient and sufficient based on their measured serum concentrations of 25-(OH) vitamin D. There was a significant difference between the group with insufficient levels of vitamin D in comparison with the group with sufficient levels of vitamin D in terms of total cholesterol, LDL and triglyceride levels, HDL, VLDL, FBS and atherogenic index (LDL/HDL) (p=0.000). \u0000Conclusion: The present results showed that there is a significant relationship between level 25-(OH) D and atherogenic index (LDL/HDL) and the incidence of metabolic syndrome.","PeriodicalId":22117,"journal":{"name":"Tabari Biomedical Student Research Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89113935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Seroepidemiological Study of Hepatitis A in Medical Students of Mazandaran University of Medical Sciences in 2019 马赞达兰医科大学2019年医学生甲型肝炎血清流行病学研究
Pub Date : 2021-11-23 DOI: 10.18502/tbsrj.v3i4.7795
Saman Shirazinia, N. Shayan, Negin Ghiyasi Moghaddam, Nima Ameli, S. Alian, L. Davoodi
Introduction: Hepatitis A (HA) is a common infectious disease caused by the HA virus that primarily affects the liver. We need to determine the safety status and infection rate in the community. Therefore, we decided to study the Seroepidemiological of HA in medical students of Mazandaran University of Medical Sciences in 2019.Material and Methods: This was a cross-sectional descriptive-analytical study prospectively examining anti-HAV antibodies in medical students of Mazandaran University of Medical Sciences in 2019. Patient demographic data, laboratory results of anti-HAV IgG and vaccination history were recorded. Four cc of blood were drawn from each student for the anti-HAV IgG test and after the test was performed. Data were analyzed using SPSS 24 software.Results: One hundred and fifty-five students were interviewed. The mean age (standard deviation) of the students in this study was 23.81 (1.47) years. Ninety-nine (63.9%) of the students were male. Therefore, it was caused by previous infection with HAV and 120 (77.4%) cases were considered susceptible individuals whose serum anti-HAV IgG was negative. This was not seen to be statistically significant (P=0.754). According to the test, 77.4% of the predictions were correct. None of the variables of sex, age, history of underlying disease, place of residence, and history of travel had a significant effect on the incidence and positivity of anti-HAV IgG.Conclusion: This study showed that the incidence of anti-HAV IgG was positive in 22.6% of the students, which is much lower than previous studies. This may be due to the higher level of health in this segment of the population.
简介:甲型肝炎(HA)是一种由HA病毒引起的常见传染病,主要影响肝脏。我们需要确定社区的安全状况和感染率。因此,我们决定对2019年马赞达兰医科大学医学生HA的血清流行病学进行研究。材料和方法:这是一项横断面描述性分析研究,前瞻性地检测了Mazandaran医科大学2019年医学生的抗hav抗体。记录患者人口统计学资料、实验室抗甲肝IgG检测结果和疫苗接种史。从每个学生身上抽取4毫升血液进行抗甲型肝炎IgG检测,并在检测完成后进行检测。数据分析采用SPSS 24软件。结果:共访谈155名学生。本研究学生的平均年龄(标准差)为23.81(1.47)岁。男生99人(63.9%)。血清抗-HAV IgG阴性120例(77.4%)为易感人群。这在统计学上没有显著性(P=0.754)。根据测试,77.4%的预测是正确的。性别、年龄、基础疾病史、居住地、旅行史等变量对抗- hav IgG的发生率和阳性率均无显著影响。结论:本研究显示,22.6%的学生抗- hav IgG阳性,明显低于以往的研究。这可能是由于这部分人口的健康水平较高。
{"title":"Seroepidemiological Study of Hepatitis A in Medical Students of Mazandaran University of Medical Sciences in 2019","authors":"Saman Shirazinia, N. Shayan, Negin Ghiyasi Moghaddam, Nima Ameli, S. Alian, L. Davoodi","doi":"10.18502/tbsrj.v3i4.7795","DOIUrl":"https://doi.org/10.18502/tbsrj.v3i4.7795","url":null,"abstract":"Introduction: Hepatitis A (HA) is a common infectious disease caused by the HA virus that primarily affects the liver. We need to determine the safety status and infection rate in the community. Therefore, we decided to study the Seroepidemiological of HA in medical students of Mazandaran University of Medical Sciences in 2019.Material and Methods: This was a cross-sectional descriptive-analytical study prospectively examining anti-HAV antibodies in medical students of Mazandaran University of Medical Sciences in 2019. Patient demographic data, laboratory results of anti-HAV IgG and vaccination history were recorded. Four cc of blood were drawn from each student for the anti-HAV IgG test and after the test was performed. Data were analyzed using SPSS 24 software.Results: One hundred and fifty-five students were interviewed. The mean age (standard deviation) of the students in this study was 23.81 (1.47) years. Ninety-nine (63.9%) of the students were male. Therefore, it was caused by previous infection with HAV and 120 (77.4%) cases were considered susceptible individuals whose serum anti-HAV IgG was negative. This was not seen to be statistically significant (P=0.754). According to the test, 77.4% of the predictions were correct. None of the variables of sex, age, history of underlying disease, place of residence, and history of travel had a significant effect on the incidence and positivity of anti-HAV IgG.Conclusion: This study showed that the incidence of anti-HAV IgG was positive in 22.6% of the students, which is much lower than previous studies. This may be due to the higher level of health in this segment of the population.","PeriodicalId":22117,"journal":{"name":"Tabari Biomedical Student Research Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77734340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Tabari Biomedical Student Research Journal
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