Pub Date : 2023-05-31DOI: 10.32598/tbsrj.v5i1.10524
Farnaz Soltani, Esmaeil Rezazadeh Bazaz, F. Mashhadi, Mohammad Taha Saadati Rad, Hannah Humphries, Z. Ghaffari, M. Ayyasi
Introduction: Vitiligo is an autoimmune disease that is caused by the destruction of melanocytes and is appeared as depigmented patches on skin and mucosa. There have been various reports of serum Vitamin D levels in patients with vitiligo. The present study aimed to Evaluation of serum Vitamin D levels in patients with vitiligo. Material and Methods: A case-control study was performed on 138 samples among people referring to Sabzevar Vasei clinic in the period of 2018-2019. The research units meeting the inclusion criteria were selected using convenience sampling and then divided into two group case and control (69 patients and 69 healthy people). After obtaining informed consent and completing the checklist of demographic characteristics, blood samples were taken from both groups and serum levels of Vitamin D in both groups were evaluated and compared. Data were analyzed using SPSS 20 via the independent t-test, chi-square test, Mann-Whitney test, Spearman correlation at a significance level of less than 0.01. Results: In total, 131 participants completed the study; the two groups did not differ significantly in terms of age nor gender. At the end of the study, the mean of serum levels of Vitamin D in was significantly lower in the patients with vitiligo than in the people without vitiligo (P <0.001). Conclusion: The results showed that serum Vitamin D levels in patients with vitiligo are lower than in those who do not have vitiligo. Therefore, it is recommended to measure the serum level of Vitamin D in these patients and if it is low, a treatment regimen should begin for these patients.
{"title":"Evaluation of Serum Levels of Vitamin D in Patients with Vitiligo: A Case-Control Study","authors":"Farnaz Soltani, Esmaeil Rezazadeh Bazaz, F. Mashhadi, Mohammad Taha Saadati Rad, Hannah Humphries, Z. Ghaffari, M. Ayyasi","doi":"10.32598/tbsrj.v5i1.10524","DOIUrl":"https://doi.org/10.32598/tbsrj.v5i1.10524","url":null,"abstract":"Introduction: Vitiligo is an autoimmune disease that is caused by the destruction of melanocytes and is appeared as depigmented patches on skin and mucosa. There have been various reports of serum Vitamin D levels in patients with vitiligo. The present study aimed to Evaluation of serum Vitamin D levels in patients with vitiligo. Material and Methods: A case-control study was performed on 138 samples among people referring to Sabzevar Vasei clinic in the period of 2018-2019. The research units meeting the inclusion criteria were selected using convenience sampling and then divided into two group case and control (69 patients and 69 healthy people). After obtaining informed consent and completing the checklist of demographic characteristics, blood samples were taken from both groups and serum levels of Vitamin D in both groups were evaluated and compared. Data were analyzed using SPSS 20 via the independent t-test, chi-square test, Mann-Whitney test, Spearman correlation at a significance level of less than 0.01. Results: In total, 131 participants completed the study; the two groups did not differ significantly in terms of age nor gender. At the end of the study, the mean of serum levels of Vitamin D in was significantly lower in the patients with vitiligo than in the people without vitiligo (P <0.001). Conclusion: The results showed that serum Vitamin D levels in patients with vitiligo are lower than in those who do not have vitiligo. Therefore, it is recommended to measure the serum level of Vitamin D in these patients and if it is low, a treatment regimen should begin for these patients.","PeriodicalId":22117,"journal":{"name":"Tabari Biomedical Student Research Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88902564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-31DOI: 10.32598/tbsrj.v5i1.10526
N. Hoshyari, A. Mesgarani, M. Moosazadeh, Arash Alimirzaei, Fateme DoostMohammad
Introduction: Dental health professionals and patients are at high risk of COVID-19 exposure due to blood and saliva droplets generated during dental procedures. People’s adherence for infection control is affected by their knowledge, attitudes, and practices towards COVID-19. Considering that dental practice is one of the most dangerous professions in terms of exposure to the disease, this study examines the knowledge and attitudes of dentists regarding COVID-19 in north of Iran. Material and Methods: This descriptive study was based on questionnaires that were distributed among dentists in north of Iran. Demographic characteristics, knowledge of participants about COVID-19 and infection control measures and their attitudes were evaluated. The effect of pandemic on dentists’ life and quality of dental services were also investigated. Results: Totally, 125 dentists completed the questionnaire (99 general dentists and 26 specialists). The majority of participants (n=84, 67.2%) did not perform unnecessary dental procedures during the pandemic, and 114 (91.2%) of them changed their working hours. The most of contributors (N=207, 86%) focus on preventive care, not perform unnecessary treatments and reduce the treatment sessions at the lowest possible. Conclusion: The present study concluded that majority of the participants had good knowledge and positive attitude regarding dental care and related preventive measures in the pandemic period. Although, it is suggested that dental health professionals continue to strengthen knowledge and improve attitude by health training programs.
{"title":"Evaluation of Dentists' Knowledge and Attitude towards COVID-19 in Sari in 2021","authors":"N. Hoshyari, A. Mesgarani, M. Moosazadeh, Arash Alimirzaei, Fateme DoostMohammad","doi":"10.32598/tbsrj.v5i1.10526","DOIUrl":"https://doi.org/10.32598/tbsrj.v5i1.10526","url":null,"abstract":"Introduction: Dental health professionals and patients are at high risk of COVID-19 exposure due to blood and saliva droplets generated during dental procedures. People’s adherence for infection control is affected by their knowledge, attitudes, and practices towards COVID-19. Considering that dental practice is one of the most dangerous professions in terms of exposure to the disease, this study examines the knowledge and attitudes of dentists regarding COVID-19 in north of Iran. Material and Methods: This descriptive study was based on questionnaires that were distributed among dentists in north of Iran. Demographic characteristics, knowledge of participants about COVID-19 and infection control measures and their attitudes were evaluated. The effect of pandemic on dentists’ life and quality of dental services were also investigated. Results: Totally, 125 dentists completed the questionnaire (99 general dentists and 26 specialists). The majority of participants (n=84, 67.2%) did not perform unnecessary dental procedures during the pandemic, and 114 (91.2%) of them changed their working hours. The most of contributors (N=207, 86%) focus on preventive care, not perform unnecessary treatments and reduce the treatment sessions at the lowest possible. Conclusion: The present study concluded that majority of the participants had good knowledge and positive attitude regarding dental care and related preventive measures in the pandemic period. Although, it is suggested that dental health professionals continue to strengthen knowledge and improve attitude by health training programs.","PeriodicalId":22117,"journal":{"name":"Tabari Biomedical Student Research Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82672124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-31DOI: 10.32598/tbsrj.v5i1.10529
H. Jafarpour, Nazanin Reisi, Farzad Zeynali, Ali Anjam, Ahmad Tajallikhah
Introduction: Herpes zoster, which is infected with varicella zoster virus (VZV), is a neurological infection and an immunodeficiency syndrome. Most patients who contact physicians complain of itchy and sometimes painful skin rashes. Herpes zoster, also known as "shingles," results from the reactivation of VZV in the dorsal ganglia. Most skin patches occur on the hands or abdomen; rashes on the feet are rare. We aimed to report Herpes zoster presentation in the foot. Case Presentation: A 47-year-old male patient presented to private practice with a rash, itching, and pain in the left lower extremity for 3 days. He was diagnosed with herpes zoster and symptoms were relieved by the administration of acyclovir five times daily for one week. The patient was advised to use Calamine lotion, a cool bath, and a cold compress to relieve the pain and itching. On his next visit to the office, the rash on the left lower extremity disappeared after using the prescriptions and methods. Conclusion: Considering that the prevalence of herpes zoster in the hands and feet is very low and only 7 cases have been reported in the world. This case was reported for the first time in Iran. Knowing the presentation of the disease and getting to know the patients' complaints can help in timely diagnosis and control.
{"title":"Atypical Presentation of Herpes Zoster: A Clinical Case Report","authors":"H. Jafarpour, Nazanin Reisi, Farzad Zeynali, Ali Anjam, Ahmad Tajallikhah","doi":"10.32598/tbsrj.v5i1.10529","DOIUrl":"https://doi.org/10.32598/tbsrj.v5i1.10529","url":null,"abstract":"Introduction: Herpes zoster, which is infected with varicella zoster virus (VZV), is a neurological infection and an immunodeficiency syndrome. Most patients who contact physicians complain of itchy and sometimes painful skin rashes. Herpes zoster, also known as \"shingles,\" results from the reactivation of VZV in the dorsal ganglia. Most skin patches occur on the hands or abdomen; rashes on the feet are rare. We aimed to report Herpes zoster presentation in the foot. Case Presentation: A 47-year-old male patient presented to private practice with a rash, itching, and pain in the left lower extremity for 3 days. He was diagnosed with herpes zoster and symptoms were relieved by the administration of acyclovir five times daily for one week. The patient was advised to use Calamine lotion, a cool bath, and a cold compress to relieve the pain and itching. On his next visit to the office, the rash on the left lower extremity disappeared after using the prescriptions and methods. Conclusion: Considering that the prevalence of herpes zoster in the hands and feet is very low and only 7 cases have been reported in the world. This case was reported for the first time in Iran. Knowing the presentation of the disease and getting to know the patients' complaints can help in timely diagnosis and control.","PeriodicalId":22117,"journal":{"name":"Tabari Biomedical Student Research Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76179541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-11DOI: 10.32598/tbsrj.v4i4.10518
T. Molania
Introduction: Due to the importance of e-learning in universities, this study was conducted to assess the readiness of faculties, to evaluate each of the e-learning infrastructures, and to assess the needs of virtual education development in Mazandaran University of Medical Sciences (MAZUMS) in 2020-21. Material and Methods: This cross-sectional descriptive study was conducted among 124 professors from 9 faculties of MAZUMS. The data collection tool in this study included 3 questionnaires which were filled by the participants. Data collection was done by the help of employees in each faculty. Collected data were entered into SPSS20 software for statistical analysis. Results: The readiness assessment score in the field of e-learning development was almost appropriate based on the participants’ views. Among the studied areas, the highest and lowest scores were related to the areas of faculty members’ readiness and financial readiness, respectively. The highest and lowest number of faculty members, equipment and physical resources were in the Sari Medical School and Behshahr Nursing and Midwifery School, respectively. Conclusion: The deputies and officials of the education development offices of each faculty had a good attitude towards the development of virtual education. In order to develop virtual education in each faculty, short-term and long-term planning based on the faculty's capacities, allocating the required resources, and empowering more students in the field of virtual education seems necessary.
{"title":"Virtual Education Infrastructures in Mazandaran University of Medical Sciences during COVID-19 Pandemic","authors":"T. Molania","doi":"10.32598/tbsrj.v4i4.10518","DOIUrl":"https://doi.org/10.32598/tbsrj.v4i4.10518","url":null,"abstract":"Introduction: Due to the importance of e-learning in universities, this study was conducted to assess the readiness of faculties, to evaluate each of the e-learning infrastructures, and to assess the needs of virtual education development in Mazandaran University of Medical Sciences (MAZUMS) in 2020-21. Material and Methods: This cross-sectional descriptive study was conducted among 124 professors from 9 faculties of MAZUMS. The data collection tool in this study included 3 questionnaires which were filled by the participants. Data collection was done by the help of employees in each faculty. Collected data were entered into SPSS20 software for statistical analysis. Results: The readiness assessment score in the field of e-learning development was almost appropriate based on the participants’ views. Among the studied areas, the highest and lowest scores were related to the areas of faculty members’ readiness and financial readiness, respectively. The highest and lowest number of faculty members, equipment and physical resources were in the Sari Medical School and Behshahr Nursing and Midwifery School, respectively. Conclusion: The deputies and officials of the education development offices of each faculty had a good attitude towards the development of virtual education. In order to develop virtual education in each faculty, short-term and long-term planning based on the faculty's capacities, allocating the required resources, and empowering more students in the field of virtual education seems necessary.","PeriodicalId":22117,"journal":{"name":"Tabari Biomedical Student Research Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75558320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-11DOI: 10.32598/tbsrj.v4i4.10520
Mahdi Shooraj, Maryam Al-sadat Mousavi Zade, S. Mahdavi
Introduction: Malaria is one of the most common chief health problems all over the world and pharmacotherapy is the common treatment for this disease. Additionally, mankind is blessed with varied range of herbal plants for several ailments which are useful for malaria treatment. The purpose of this investigation is to review the existing studies on the effectiveness of herbal plants in treatment of malaria. Material and Methods: In this study, related articles were reviewed based on keywords and phrases such as antimalarial drugs, herbal plants, treatment in PubMed, Google Scholar, IranDoc and SID (Scientific Information Database) databases from 2003 to 2022. Results: The findings revealed that the main problem associated with medical treatment is emergence of drug resistance which leads to treatment failure in significant cases and results in the antimalarials’ ineffective drugs. Therefore, the chief available alternative since ancient times is medicinal plants all over the world. The review revealed that more than 2000 medicinal plant species from different families were traditionally used in the treatment of malaria and most of them confirmed antimalarial activities. Conclusion: It looks critical to take an effective action for developing a perfect malaria vaccine which would work properly by activating the immune system to destroy all the parasites. The current investigation is useful for researchers and pharmaco-therapists.
疟疾是世界上最常见的主要健康问题之一,药物治疗是这种疾病的常用治疗方法。此外,人类有幸拥有各种各样的草药植物,用于治疗几种疾病,这些植物对治疗疟疾很有用。本调查的目的是回顾现有的草药治疗疟疾的有效性的研究。材料与方法:本研究基于PubMed、Google Scholar、IranDoc和SID (Scientific Information Database)数据库中2003 - 2022年的抗疟药物、草药、治疗等关键词和短语进行综述。结果:与药物治疗相关的主要问题是耐药性的出现,导致大量病例治疗失败,导致抗疟药物无效。因此,自古以来,世界各地的主要可用替代品是药用植物。综述发现,来自不同科的2000多种药用植物传统上用于治疗疟疾,其中大多数已证实具有抗疟疾活性。结论:目前迫切需要采取有效措施,开发出一种能够激活免疫系统、有效消灭疟原虫的疟疾疫苗。目前的研究对研究人员和药物治疗师很有帮助。
{"title":"A Review on Herbal Treatments of Malaria","authors":"Mahdi Shooraj, Maryam Al-sadat Mousavi Zade, S. Mahdavi","doi":"10.32598/tbsrj.v4i4.10520","DOIUrl":"https://doi.org/10.32598/tbsrj.v4i4.10520","url":null,"abstract":"Introduction: Malaria is one of the most common chief health problems all over the world and pharmacotherapy is the common treatment for this disease. Additionally, mankind is blessed with varied range of herbal plants for several ailments which are useful for malaria treatment. The purpose of this investigation is to review the existing studies on the effectiveness of herbal plants in treatment of malaria. Material and Methods: In this study, related articles were reviewed based on keywords and phrases such as antimalarial drugs, herbal plants, treatment in PubMed, Google Scholar, IranDoc and SID (Scientific Information Database) databases from 2003 to 2022. Results: The findings revealed that the main problem associated with medical treatment is emergence of drug resistance which leads to treatment failure in significant cases and results in the antimalarials’ ineffective drugs. Therefore, the chief available alternative since ancient times is medicinal plants all over the world. The review revealed that more than 2000 medicinal plant species from different families were traditionally used in the treatment of malaria and most of them confirmed antimalarial activities. Conclusion: It looks critical to take an effective action for developing a perfect malaria vaccine which would work properly by activating the immune system to destroy all the parasites. The current investigation is useful for researchers and pharmaco-therapists.","PeriodicalId":22117,"journal":{"name":"Tabari Biomedical Student Research Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76965165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-11DOI: 10.32598/tbsrj.v4i4.10519
Marzieh Zamaniyan, Atefeh Esmati, S. Peyvandi, M. Moosazadeh, Seyedeh Fatemeh Kalantari, Maesommeh Hamedi, Mohammad Zahedi
Introduction: Husband artificial intrauterine insemination (IUI) is a standard method of assisted reproduction for patients with mild male infertility, anovulation, endometriosis, and unknown infertility. In this study, we evaluated the effect of luteal phase support on the success rate of IUI cycles with vaginal micronized progesterone compared to the control. Material and Methods: This retrospective cohort study included 94 infertile women referring to two infertility centers in Sari, Iran, from 2015 to 2021. In these women, Clomiphene citrate or Letrozole was used, follicular monitoring continued, and human Gonadotropin was added based on ultra-sonographic findings. Intramuscular HCG was added when one or two follicles were to 17 mm. IUI was done 36 hours later, and micronized vaginal progesterone 400mg once daily was added on the day after insemination (n=114). IUI outcomes were evaluated with a serum Beta-HCG test and vaginal ultrasound two and five weeks later. Pregnant women were followed up until the end of the pregnancy. Data were analyzed with SPSS25 and STATA14 software. Results: Progesterone consumption had no significant relationship with pregnancy rates but a significant correlation with the number of antral follicles. Pregnancy occurrence was significantly associated with patient satisfaction, FSH, and AMH levels but not correlated with the duration and kinds of infertility. Conclusion: Vaginal micronized progesterone as luteal phase support is not effective in increasing pregnancy occurrences in IUI cycles like IVF cycles, but patients’ satisfaction may be increased among women impregnated undergoing IUI and progesterone support.
{"title":"Does luteal Phase Support with Vaginal Micronized Progesterone Effect on Pregnancy Rates in Intrauterine Insemination (IUI) Cycles in Two Infertility Center During Six-Year Follow-up?","authors":"Marzieh Zamaniyan, Atefeh Esmati, S. Peyvandi, M. Moosazadeh, Seyedeh Fatemeh Kalantari, Maesommeh Hamedi, Mohammad Zahedi","doi":"10.32598/tbsrj.v4i4.10519","DOIUrl":"https://doi.org/10.32598/tbsrj.v4i4.10519","url":null,"abstract":"Introduction: Husband artificial intrauterine insemination (IUI) is a standard method of assisted reproduction for patients with mild male infertility, anovulation, endometriosis, and unknown infertility. In this study, we evaluated the effect of luteal phase support on the success rate of IUI cycles with vaginal micronized progesterone compared to the control. Material and Methods: This retrospective cohort study included 94 infertile women referring to two infertility centers in Sari, Iran, from 2015 to 2021. In these women, Clomiphene citrate or Letrozole was used, follicular monitoring continued, and human Gonadotropin was added based on ultra-sonographic findings. Intramuscular HCG was added when one or two follicles were to 17 mm. IUI was done 36 hours later, and micronized vaginal progesterone 400mg once daily was added on the day after insemination (n=114). IUI outcomes were evaluated with a serum Beta-HCG test and vaginal ultrasound two and five weeks later. Pregnant women were followed up until the end of the pregnancy. Data were analyzed with SPSS25 and STATA14 software. Results: Progesterone consumption had no significant relationship with pregnancy rates but a significant correlation with the number of antral follicles. Pregnancy occurrence was significantly associated with patient satisfaction, FSH, and AMH levels but not correlated with the duration and kinds of infertility. Conclusion: Vaginal micronized progesterone as luteal phase support is not effective in increasing pregnancy occurrences in IUI cycles like IVF cycles, but patients’ satisfaction may be increased among women impregnated undergoing IUI and progesterone support.","PeriodicalId":22117,"journal":{"name":"Tabari Biomedical Student Research Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87321565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-11DOI: 10.32598/tbsrj.v4i4.10522
Z. Karimi, M. Shokrzadeh, A. Abbasi, V. Sharifi
A Simple and fast QuEChERS method has been applied for extraction of imidacloprid from human biological samples. Imidacloprid the was extracted from blood and liver of a deceased body admitted to the legal Medicine of Mazandaran. Factors affecting the extraction procedure such as type of the organic solvent and its volume, amount of salt, amount of sorbent, and pH were examined and optimized for the maximum recovery. The appropriate condition for extraction of imidacloprid was as follows: sample pH=5, 3mL of acetonitrile, 0.1 g of NaCl, and 0.4 g of MgSO4. The maximum recovery of imidacloprid at these conditions was 96%. The LOD and LOQ were 0.02 and 0.06 ppm, respectively. Finally, the blood and liver samples were extracted under the appropriate condition and determined using HPLC which is equipped with a photodiode array detector. The amounts of Imidacloprid in blood and liver samples were 11 and 1.8 ppm, respectively.
{"title":"Extraction of Imidacloprid from Human Biological Samples Using the QuEChERS Method and Its Determination by High-Performance Liquid Chromatography","authors":"Z. Karimi, M. Shokrzadeh, A. Abbasi, V. Sharifi","doi":"10.32598/tbsrj.v4i4.10522","DOIUrl":"https://doi.org/10.32598/tbsrj.v4i4.10522","url":null,"abstract":"A Simple and fast QuEChERS method has been applied for extraction of imidacloprid from human biological samples. Imidacloprid the was extracted from blood and liver of a deceased body admitted to the legal Medicine of Mazandaran. Factors affecting the extraction procedure such as type of the organic solvent and its volume, amount of salt, amount of sorbent, and pH were examined and optimized for the maximum recovery. The appropriate condition for extraction of imidacloprid was as follows: sample pH=5, 3mL of acetonitrile, 0.1 g of NaCl, and 0.4 g of MgSO4. The maximum recovery of imidacloprid at these conditions was 96%. The LOD and LOQ were 0.02 and 0.06 ppm, respectively. Finally, the blood and liver samples were extracted under the appropriate condition and determined using HPLC which is equipped with a photodiode array detector. The amounts of Imidacloprid in blood and liver samples were 11 and 1.8 ppm, respectively.","PeriodicalId":22117,"journal":{"name":"Tabari Biomedical Student Research Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77551736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-11DOI: 10.32598/tbsrj.v4i4.10517
M. Javdani, Farid Shahbandari, Ehsan Soleymanijadian, M. Hashemnia, A. Barzegar
Introduction: Nowadays non-alcoholic fatty liver disease (NAFAD) is considered as a serious problem in human societies. Recently, the possibility of an association between endometriosis and NAFAD has been considered. This study was designed to evaluate some general inflammation parameters and hepatic lesions during and after experimental endometriosis. Material and Methods: In 20 female rats, the endometriosis model was induced by suturing parts of the uterine horn wall to the mesenteric gut. After four weeks, the rats in group I were euthanized and endometriosis cysts and some fragments of their liver were used for histopathological evaluation. At the same time, endometrial cysts were surgically removed in the rats of group II and they were kept for four weeks later. In addition, hematobiochemical evaluation was performed. In group II, similar evaluative investigations were performed 8 weeks after experimental surgery. Results: Significant increase in triglyceride, LDL, AST, ALP, ALT and estrogen parameters was observed in this study (P˂0.05), Whereas, total WBC count, lymphocyte, PCV and HDL level decreased significantly (P˂0.05). In histopathological evaluation, induction of endometriosis was confirmed at the microscopic level, but no evidence of fatty liver or hepatic inflammation was found. Conclusion: Despite notable changes in some hematobiochemical factors in rats with experimental endometriosis, there was no evidence of fatty liver and hepatic inflammation. Therefore, there may be no association between endometriosis and non-alcoholic fatty liver disease.
{"title":"Induction of Experimental Endometriosis in Rat: Evaluation of Systemic Inflammatory Response and Liver Tissue Changes","authors":"M. Javdani, Farid Shahbandari, Ehsan Soleymanijadian, M. Hashemnia, A. Barzegar","doi":"10.32598/tbsrj.v4i4.10517","DOIUrl":"https://doi.org/10.32598/tbsrj.v4i4.10517","url":null,"abstract":"Introduction: Nowadays non-alcoholic fatty liver disease (NAFAD) is considered as a serious problem in human societies. Recently, the possibility of an association between endometriosis and NAFAD has been considered. This study was designed to evaluate some general inflammation parameters and hepatic lesions during and after experimental endometriosis. Material and Methods: In 20 female rats, the endometriosis model was induced by suturing parts of the uterine horn wall to the mesenteric gut. After four weeks, the rats in group I were euthanized and endometriosis cysts and some fragments of their liver were used for histopathological evaluation. At the same time, endometrial cysts were surgically removed in the rats of group II and they were kept for four weeks later. In addition, hematobiochemical evaluation was performed. In group II, similar evaluative investigations were performed 8 weeks after experimental surgery. Results: Significant increase in triglyceride, LDL, AST, ALP, ALT and estrogen parameters was observed in this study (P˂0.05), Whereas, total WBC count, lymphocyte, PCV and HDL level decreased significantly (P˂0.05). In histopathological evaluation, induction of endometriosis was confirmed at the microscopic level, but no evidence of fatty liver or hepatic inflammation was found. Conclusion: Despite notable changes in some hematobiochemical factors in rats with experimental endometriosis, there was no evidence of fatty liver and hepatic inflammation. Therefore, there may be no association between endometriosis and non-alcoholic fatty liver disease.","PeriodicalId":22117,"journal":{"name":"Tabari Biomedical Student Research Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82906833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-11DOI: 10.32598/tbsrj.v4i4.10521
Zeinab Hamzehgardashi, Z. Keshavarz, M. Fakhri, M. Nasiri, Seyedeh Zeynab Hoseinnezhad, Leila Shasti
Introduction: HPV is one of the most common sexually transmitted infections. The Gardasil vaccine can act as a prophylactic against the virus. Since parents are very important in adolescents 'decisions, this study is a review of interventions affecting parents' knowledge and attitudes about HPV vaccine through a systematic review method. Material and Methods: This study was conducted in 2022 with steps, designing a study question, identifying related studies from 2005 to 2022. Selecting studies out of 818 studies, 10 articles were selected to announce the results and then the data were classified. The relevant search was performed in the available databases. The keywords were selected based on the mesh according to the text. Results: A total of 10 experimental and quasi-experimental studies were reviewed. The results of these studies were divided into four categories according to the type of intervention and the statistical population in the intervention group located in each study: face-to-face group education, virtual group education, community-based education, and intervention based on health belief model. Eight studies were conducted in the face-to-face and virtual group education category. In the community-based education category, the interventions were performed virtually and there is a study. The other category, which was related to the health belief model, also changed the knowledge and attitude of parents. Conclusion: The results showed that interventions for parents are effective in vaccination and changes in knowledge and attitude. Therefore, it is recommended that different methods of educational intervention be used to encourage parents to get the HPV vaccine for their adolescents.
{"title":"A Systematic Review on Interventions Affecting Parents' Knowledge and Attitudes about HPV Vaccine","authors":"Zeinab Hamzehgardashi, Z. Keshavarz, M. Fakhri, M. Nasiri, Seyedeh Zeynab Hoseinnezhad, Leila Shasti","doi":"10.32598/tbsrj.v4i4.10521","DOIUrl":"https://doi.org/10.32598/tbsrj.v4i4.10521","url":null,"abstract":"Introduction: HPV is one of the most common sexually transmitted infections. The Gardasil vaccine can act as a prophylactic against the virus. Since parents are very important in adolescents 'decisions, this study is a review of interventions affecting parents' knowledge and attitudes about HPV vaccine through a systematic review method. Material and Methods: This study was conducted in 2022 with steps, designing a study question, identifying related studies from 2005 to 2022. Selecting studies out of 818 studies, 10 articles were selected to announce the results and then the data were classified. The relevant search was performed in the available databases. The keywords were selected based on the mesh according to the text. Results: A total of 10 experimental and quasi-experimental studies were reviewed. The results of these studies were divided into four categories according to the type of intervention and the statistical population in the intervention group located in each study: face-to-face group education, virtual group education, community-based education, and intervention based on health belief model. Eight studies were conducted in the face-to-face and virtual group education category. In the community-based education category, the interventions were performed virtually and there is a study. The other category, which was related to the health belief model, also changed the knowledge and attitude of parents. Conclusion: The results showed that interventions for parents are effective in vaccination and changes in knowledge and attitude. Therefore, it is recommended that different methods of educational intervention be used to encourage parents to get the HPV vaccine for their adolescents.","PeriodicalId":22117,"journal":{"name":"Tabari Biomedical Student Research Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86854399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-04DOI: 10.18502/tbsrj.v4i3.10513
F. Araghian Mojarad, H. Salehiniya, L. Davoodi, Masoumeh Ghasemian, Nahid Nazari, Abolfazl Ebrahimzadeh, Kobra Abdi
Introduction: Telephone follow-up is known for sharing information, providing health education, diagnosing complications quickly, managing symptoms, and providing quality aftercare services. The aim of this study was to investigate the effect of patient education and telephone follow-up on self-care and self-efficacy as well as readmission rate of heart patients with COVID-19. Material and Methods: In this interventional study, 64 heart patients with COVID-19 admitted to a training center in northern Iran during the period from June 1 to September 22, in 2020 were intervened. Data collection tools included demographic and clinical questionnaires, Scherer self-care and self-efficacy questionnaires. After completing the questionnaires and teaching self-care about corona disease and heart disease to patients during six sessions over the phone (10-20 minutes), the researcher again completed the self-care and self-efficacy questionnaires on the fourteenth day. For data analysis, paired t-test and independent t-test were used using SPSS software version 21. Results: The mean age of participants was 59.53±15.32. The results showed that the mean score of self- care after the intervention had a significant increase (P<0.001), so that the mean score of self- care before the intervention was 54 and after the intervention was 60.14, the mean score of self-efficacies after the intervention increased which is not statistically significant. Conclusion: Education and follow-up of heart patients with COVID-19 is associated with increased self-care in patients every day. Therefore, follow-up programs, especially telephone follow-up, are recommended to improve the health status of patients.
{"title":"Evaluation of the Effect of Patient Education and Telephone Follow-Up on Self-Care, Self-Efficacy, and Admission Rate of Heart Patients with COVID-19","authors":"F. Araghian Mojarad, H. Salehiniya, L. Davoodi, Masoumeh Ghasemian, Nahid Nazari, Abolfazl Ebrahimzadeh, Kobra Abdi","doi":"10.18502/tbsrj.v4i3.10513","DOIUrl":"https://doi.org/10.18502/tbsrj.v4i3.10513","url":null,"abstract":"Introduction: Telephone follow-up is known for sharing information, providing health education, diagnosing complications quickly, managing symptoms, and providing quality aftercare services. The aim of this study was to investigate the effect of patient education and telephone follow-up on self-care and self-efficacy as well as readmission rate of heart patients with COVID-19. \u0000Material and Methods: In this interventional study, 64 heart patients with COVID-19 admitted to a training center in northern Iran during the period from June 1 to September 22, in 2020 were intervened. Data collection tools included demographic and clinical questionnaires, Scherer self-care and self-efficacy questionnaires. After completing the questionnaires and teaching self-care about corona disease and heart disease to patients during six sessions over the phone (10-20 minutes), the researcher again completed the self-care and self-efficacy questionnaires on the fourteenth day. For data analysis, paired t-test and independent t-test were used using SPSS software version 21. \u0000Results: The mean age of participants was 59.53±15.32. The results showed that the mean score of self- care after the intervention had a significant increase (P<0.001), so that the mean score of self- care before the intervention was 54 and after the intervention was 60.14, the mean score of self-efficacies after the intervention increased which is not statistically significant. \u0000Conclusion: Education and follow-up of heart patients with COVID-19 is associated with increased self-care in patients every day. Therefore, follow-up programs, especially telephone follow-up, are recommended to improve the health status of patients.","PeriodicalId":22117,"journal":{"name":"Tabari Biomedical Student Research Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80100503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}