Pub Date : 2018-01-01DOI: 10.4172/2161-0932.1000483
Wu Hr, Allybocusa Za, Ma Xy, Shibata Hr
Wua HR1, Allybocusa ZA1*, Maa XY2 and Shib HR2 1Center of Genetics and Prenatal Diagnosis, China 2Department of Gynecology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan province, China *Corresponding author: Allybocusa ZA, Center of Genetics and Prenatal Diagnosis, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan province, China, Tel: 0086-66913236; E-mail: qh_wu77@163.com
{"title":"First Reported Cases of Robinow-Sorauf Syndrome in a Three-Generation Family in China, a Mutation c.395G>C of TWIST1 Gene as Identified by Next Generation Sequencing","authors":"Wu Hr, Allybocusa Za, Ma Xy, Shibata Hr","doi":"10.4172/2161-0932.1000483","DOIUrl":"https://doi.org/10.4172/2161-0932.1000483","url":null,"abstract":"Wua HR1, Allybocusa ZA1*, Maa XY2 and Shib HR2 1Center of Genetics and Prenatal Diagnosis, China 2Department of Gynecology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan province, China *Corresponding author: Allybocusa ZA, Center of Genetics and Prenatal Diagnosis, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan province, China, Tel: 0086-66913236; E-mail: qh_wu77@163.com","PeriodicalId":22164,"journal":{"name":"Surgery, gynecology & obstetrics","volume":"29 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72428285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.4172/2161-0932.1000487
S. Hassanpour, S. Karami
Preeclampsia is a pregnancy-related disorder and considered as one of the major reasons of infants and mothers death in developed nations. HELLP disorder is a problem related to childbirth that usually happens in women with intense preeclampsia and associated with different features, including hemolysis, elevated liver enzymes, and low platelet count. Due to normal hepatic markers during pregnancy, our purpose is to examine these factors in pregnant women and their association with disorders such as preeclampsia and HELLP syndrome. This case-control study included 99 Iranian pregnant women that were divided into two group including preeclamptic and normotensive pregnant women. Samples were collected from Ahvaz city. We measured liver enzymes activity (ALT, AST, and ALP), total bilirubin and direct bilirubin and blood platelets by calorimeter methods in both groups. The results showed that there was no significant difference in the platelet level in both groups. However, we found a significant difference in the serum level of ALT, AST, ALP and total bilirubin between two groups (p<0.05), while the result related to direct bilirubin was not significant at the end of the study. The outcomes related to this study show that hepatic biomarkers in pregnant women with preeclampsia was higher than normal pregnant women, therefore, we can predict more likely to develop HELLP syndrome in pregnant women with preeclampsia.
{"title":"Evaluation of Hepatic Biomarkers in Pregnant Women with Preeclampsia","authors":"S. Hassanpour, S. Karami","doi":"10.4172/2161-0932.1000487","DOIUrl":"https://doi.org/10.4172/2161-0932.1000487","url":null,"abstract":"Preeclampsia is a pregnancy-related disorder and considered as one of the major reasons of infants and mothers death in developed nations. HELLP disorder is a problem related to childbirth that usually happens in women with intense preeclampsia and associated with different features, including hemolysis, elevated liver enzymes, and low platelet count. Due to normal hepatic markers during pregnancy, our purpose is to examine these factors in pregnant women and their association with disorders such as preeclampsia and HELLP syndrome. This case-control study included 99 Iranian pregnant women that were divided into two group including preeclamptic and normotensive pregnant women. Samples were collected from Ahvaz city. We measured liver enzymes activity (ALT, AST, and ALP), total bilirubin and direct bilirubin and blood platelets by calorimeter methods in both groups. The results showed that there was no significant difference in the platelet level in both groups. However, we found a significant difference in the serum level of ALT, AST, ALP and total bilirubin between two groups (p<0.05), while the result related to direct bilirubin was not significant at the end of the study. The outcomes related to this study show that hepatic biomarkers in pregnant women with preeclampsia was higher than normal pregnant women, therefore, we can predict more likely to develop HELLP syndrome in pregnant women with preeclampsia.","PeriodicalId":22164,"journal":{"name":"Surgery, gynecology & obstetrics","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87454334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.4172/2161-0932.1000477
R. A. Khan
{"title":"Premarital Health and Social Issues … Suffering in Silence?","authors":"R. A. Khan","doi":"10.4172/2161-0932.1000477","DOIUrl":"https://doi.org/10.4172/2161-0932.1000477","url":null,"abstract":"","PeriodicalId":22164,"journal":{"name":"Surgery, gynecology & obstetrics","volume":"27 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75805317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.4172/2161-0932.1000480
A. Birhane, getaneh Haile, G. Abera
{"title":"Assessing Knowledge and Practice of Emergency Contraception among Female Students of Ayder Preparatory School Mekelle City, Tigray, Ethiopia","authors":"A. Birhane, getaneh Haile, G. Abera","doi":"10.4172/2161-0932.1000480","DOIUrl":"https://doi.org/10.4172/2161-0932.1000480","url":null,"abstract":"","PeriodicalId":22164,"journal":{"name":"Surgery, gynecology & obstetrics","volume":"118 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81401194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.4172/2161-0932.1000478
A. Abdou, Hossam M Abdelnaby
Objective: To compare efficacy and complications of open surgical versus laparoscopic Burch colposuspension for treatment of urodynamic stress urinary incontinence and to demonstrate the presumed advantages of laparoscopic approach. Study design: Prospective randomized trial. Methods: One hundred and four patients with urodynamic stress urinary incontinence were randomly divided into two groups; 52 patients in each.GroupA had open surgical Burch colposuspension and group B had laparoscopic Burch colposuspension. Results: There were no significant differences between both groups regarding one hour pad-test and patient satisfaction during follow up at 1, 6 and 12 months. Operative time in group B was significanly higher than group A (94±6.4 and 52.2±4.3 min, respectively). However, group B had lower pain score and shorter hospital stay than group A. There were no significant differences between both groups as regard intra operative and postoperative complications. Conclusion: Laparoscopic Burch colposuspension is a better approach than open surgical Burch in terms of hospital stay, post-operative pain and recovery, but it needs long learning curve and has longer operative time.
{"title":"Burch Colposuspension for Treatment of Urodynamic Stress Urinary Incontinence; Laparoscopic versus Open Surgical Approach. A Randomized Controlled Trial","authors":"A. Abdou, Hossam M Abdelnaby","doi":"10.4172/2161-0932.1000478","DOIUrl":"https://doi.org/10.4172/2161-0932.1000478","url":null,"abstract":"Objective: To compare efficacy and complications of open surgical versus laparoscopic Burch colposuspension for treatment of urodynamic stress urinary incontinence and to demonstrate the presumed advantages of laparoscopic approach. Study design: Prospective randomized trial. Methods: One hundred and four patients with urodynamic stress urinary incontinence were randomly divided into two groups; 52 patients in each.GroupA had open surgical Burch colposuspension and group B had laparoscopic Burch colposuspension. Results: There were no significant differences between both groups regarding one hour pad-test and patient satisfaction during follow up at 1, 6 and 12 months. Operative time in group B was significanly higher than group A (94±6.4 and 52.2±4.3 min, respectively). However, group B had lower pain score and shorter hospital stay than group A. There were no significant differences between both groups as regard intra operative and postoperative complications. Conclusion: Laparoscopic Burch colposuspension is a better approach than open surgical Burch in terms of hospital stay, post-operative pain and recovery, but it needs long learning curve and has longer operative time.","PeriodicalId":22164,"journal":{"name":"Surgery, gynecology & obstetrics","volume":"124 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77352048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.4172/2161-0932.1000479
S. P. Pérez, Judith Jurado Seguer, L. S. Azuara, J. C. Pueyo, J. L. Juanós, Antonio Payà Panadés
Background: Multiple factors have been associated with an increased risk of fetuses with increased nuchal translucency. The aim of this study was to determine the relationship between chromosomal abnormalities and increased nuchal translucency and also to assess the incremental yield of genomic microarray over conventional karyotyping in these fetuses. Methods: Prospective observational study of fetuses with increased nuchal translucency (≥ p 99th percentile) between 11 and 14 weeks of gestation diagnosed between 2013 and 2017 in our hospital. We performed a descriptive analysis of the mean, the interval and the standard deviation for continuous variables and an analysis of absolute frequency and percentages for the categorical variables. Results: Among 102 enrolled pregnant women, the incidence of increased nuchal translucency was 1%. We diagnosed 9.3% of pathological results by arrays, but 3 cases (4.6%) were diagnosed by conventional karyotype too. Incremental yield of chromosomal microarray analysis over karyotyping was 6.5%. Conclusion: The use of chromosomal microarray analysis provided a 6.5% incremental yield of detecting copy number variations in fetuses with increased translucency and normal karyotype. Prenatal array should be part of the usual study in these cases, especially if there is ultrasound malformations associated.
{"title":"Contribution of Chromosomal Microarray Analysis in fetuses with Increased Nuchal Translucency: A Prospective Observational Study","authors":"S. P. Pérez, Judith Jurado Seguer, L. S. Azuara, J. C. Pueyo, J. L. Juanós, Antonio Payà Panadés","doi":"10.4172/2161-0932.1000479","DOIUrl":"https://doi.org/10.4172/2161-0932.1000479","url":null,"abstract":"Background: Multiple factors have been associated with an increased risk of fetuses with increased nuchal translucency. The aim of this study was to determine the relationship between chromosomal abnormalities and increased nuchal translucency and also to assess the incremental yield of genomic microarray over conventional karyotyping in these fetuses. Methods: Prospective observational study of fetuses with increased nuchal translucency (≥ p 99th percentile) between 11 and 14 weeks of gestation diagnosed between 2013 and 2017 in our hospital. We performed a descriptive analysis of the mean, the interval and the standard deviation for continuous variables and an analysis of absolute frequency and percentages for the categorical variables. Results: Among 102 enrolled pregnant women, the incidence of increased nuchal translucency was 1%. We diagnosed 9.3% of pathological results by arrays, but 3 cases (4.6%) were diagnosed by conventional karyotype too. Incremental yield of chromosomal microarray analysis over karyotyping was 6.5%. Conclusion: The use of chromosomal microarray analysis provided a 6.5% incremental yield of detecting copy number variations in fetuses with increased translucency and normal karyotype. Prenatal array should be part of the usual study in these cases, especially if there is ultrasound malformations associated.","PeriodicalId":22164,"journal":{"name":"Surgery, gynecology & obstetrics","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91223384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.4172/2161-0932.1000491
Jyoti Kanchanalak
Amniocentesis is an outpatient procedure with an aim to obtain the amniotic fluid for various purposes most commonly for prenatal chromosomal diagnosis and infection screen, lung maturity and Rh incompatibility. It has been under constant evolution since 1959 by Experts. Procedure advanced from blind procedure to ultrasound guided. I have used it diligently in various obstetrics cases which saved time and helped in compiling to a planned care. If used it will definitely help obstetricians achieve very motive safe mother and child. Objective: It’s a compliment to the clinician in a critical situation with the addition to other modalities including Ultrasound.
{"title":"Novel Role of Amniocentesis-Prenatal Utility","authors":"Jyoti Kanchanalak","doi":"10.4172/2161-0932.1000491","DOIUrl":"https://doi.org/10.4172/2161-0932.1000491","url":null,"abstract":"Amniocentesis is an outpatient procedure with an aim to obtain the amniotic fluid for various purposes most commonly for prenatal chromosomal diagnosis and infection screen, lung maturity and Rh incompatibility. It has been under constant evolution since 1959 by Experts. Procedure advanced from blind procedure to ultrasound guided. I have used it diligently in various obstetrics cases which saved time and helped in compiling to a planned care. If used it will definitely help obstetricians achieve very motive safe mother and child. Objective: It’s a compliment to the clinician in a critical situation with the addition to other modalities including Ultrasound.","PeriodicalId":22164,"journal":{"name":"Surgery, gynecology & obstetrics","volume":"35 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79040663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.4172/2161-0932.1000474
Hossam M Abdelnaby, Hussin M Abdeldayem, E. F. Gerbash, M. Harira, M. Lashin, A. Abdou
Objective: The aim of this study is to compare the efficacy of single- and double-balloon catheters for the induction of labor among women with an unripe cervix. Study design: This prospective randomize interventional study was performed in emergency department of Obstetrics and Gynecology, Zagazig University and ELGALAA maternity hospitals during the period from 6/2017 till 2/2018. In this study (180 patients) who fulfill inclusion and exclusion criteria were enrolled and were divided into two main groups; single and double balloon group. Each group included equal number of prim gravida and multigravida. Result Of 180 pregnant women recruited in this study 160 continued till the end of the study. Pain encountered by using visual analogue scale during the catheter insertion the mean pain perception during catheter insertion was 3.3 ± 2.3 in the Foley catheter group and 3.1 ± 2.47 in the Cook catheter group. In the Foley catheter group there were significantly more spontaneous expulsions of the balloon compared with the Cook balloon group. In the Foley catheter group 82.2% of them delivered vaginally and 17.8% delivered by caesarean section. In cook catheter group 80% of them delivered vaginally and 18% delivered by caesarean section. Regarding maternal complications There were 4 cases of postpartum hemorrhage (PPH), 3 of them were atonic PPH, and only one case with traumatic PPH due to cervical tear in the Cook catheter group and in foley catheter group there were 3 cases of postpartum hemorrhage all of them atonic postpartum. Conclusion: There is significant difference between the two groups regarding Bishop Score after the balloon catheter expulsion or removal and it was significantly higher in the Cook cervical ripening balloon group, but only in the nulliparous group. Putting in mind that the Foley catheter is cheaper than double balloon catheter and at least as effective as Cook catheter or even better, it is recommended to use Foley catheter in induction of labor instead of double balloon catheter.
{"title":"Comparative Study for Labor Induction with the Foley Catheter and Double Balloon (cook) Catheter in Women with Unfavorable Cervix","authors":"Hossam M Abdelnaby, Hussin M Abdeldayem, E. F. Gerbash, M. Harira, M. Lashin, A. Abdou","doi":"10.4172/2161-0932.1000474","DOIUrl":"https://doi.org/10.4172/2161-0932.1000474","url":null,"abstract":"Objective: The aim of this study is to compare the efficacy of single- and double-balloon catheters for the induction of labor among women with an unripe cervix. Study design: This prospective randomize interventional study was performed in emergency department of Obstetrics and Gynecology, Zagazig University and ELGALAA maternity hospitals during the period from 6/2017 till 2/2018. In this study (180 patients) who fulfill inclusion and exclusion criteria were enrolled and were divided into two main groups; single and double balloon group. Each group included equal number of prim gravida and multigravida. Result Of 180 pregnant women recruited in this study 160 continued till the end of the study. Pain encountered by using visual analogue scale during the catheter insertion the mean pain perception during catheter insertion was 3.3 ± 2.3 in the Foley catheter group and 3.1 ± 2.47 in the Cook catheter group. In the Foley catheter group there were significantly more spontaneous expulsions of the balloon compared with the Cook balloon group. In the Foley catheter group 82.2% of them delivered vaginally and 17.8% delivered by caesarean section. In cook catheter group 80% of them delivered vaginally and 18% delivered by caesarean section. Regarding maternal complications There were 4 cases of postpartum hemorrhage (PPH), 3 of them were atonic PPH, and only one case with traumatic PPH due to cervical tear in the Cook catheter group and in foley catheter group there were 3 cases of postpartum hemorrhage all of them atonic postpartum. Conclusion: There is significant difference between the two groups regarding Bishop Score after the balloon catheter expulsion or removal and it was significantly higher in the Cook cervical ripening balloon group, but only in the nulliparous group. Putting in mind that the Foley catheter is cheaper than double balloon catheter and at least as effective as Cook catheter or even better, it is recommended to use Foley catheter in induction of labor instead of double balloon catheter.","PeriodicalId":22164,"journal":{"name":"Surgery, gynecology & obstetrics","volume":"26 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77418012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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